PMC:2728246 / 2155-2803 JSONTXT

{"project":"2_test","denotations":[{"id":"19652920-9665181-56190893","span":{"begin":172,"end":176},"obj":"9665181"},{"id":"19652920-11438724-56190894","span":{"begin":190,"end":194},"obj":"11438724"},{"id":"19652920-16973882-56190895","span":{"begin":234,"end":238},"obj":"16973882"},{"id":"19652920-16637639-56190896","span":{"begin":253,"end":257},"obj":"16637639"},{"id":"19652920-16456078-56190897","span":{"begin":272,"end":276},"obj":"16456078"},{"id":"19652920-18097416-56190898","span":{"begin":278,"end":282},"obj":"18097416"},{"id":"19652920-18026087-56190899","span":{"begin":307,"end":311},"obj":"18026087"},{"id":"19652920-19361439-56190900","span":{"begin":328,"end":332},"obj":"19361439"},{"id":"19652920-2690953-56190901","span":{"begin":602,"end":606},"obj":"2690953"},{"id":"19652920-8973171-56190902","span":{"begin":622,"end":626},"obj":"8973171"},{"id":"19652920-11462813-56190903","span":{"begin":642,"end":646},"obj":"11462813"}],"text":"Over the past decades NMR has been used to great success to collect abundant experimental evidence describing the role of internal dynamics in protein or RNA function (Kay 1998; Wang et al. 2001; Shajani and Varani 2005; Boehr et al. 2006; Brath et al. 2006; Zhang et al. 2006, 2007; Henzler-Wildman et al. 2007; Brath and Akke 2009). Initial studies based on backbone amide relaxation and relaxation dispersion methods have elucidated motional processes in the protein backbone occurring on the fast time scale (\u003cτc, ns) as well as the slower time window associated with chemical exchange (Kay et al. 1989; Mandel et al. 1996; Palmer et al. 2001)."}