PMC:2726282 / 25121-25545 JSONTXT

{"project":"2_test","denotations":[{"id":"18599074-18421347-62517948","span":{"begin":172,"end":174},"obj":"18421347"}],"text":"As shown in a recent study, the E. coli cross-regulatory network appears to be robust enough to tolerate the rewiring between members high and low in the network hierarchy.66 This study also indicates that the allosteric signals are the mandatory input elements for network function. Thus, TFs present in a condition different from the natural one(s) would have limited activity due to the absence of their effector signals."}