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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2726282","sourcedb":"PMC","sourceid":"2726282","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2726282","text":"In bacteria, coupling of gene expression with external conditions is achieved through two molecular functions: (i) binding of transcription factors (TFs) at specific sites in the genome and (ii) recognition of a relevant effector signal or metabolite.1,2 Typically, these functions are performed by different domains of a single polypeptide, but there are also cases where two interacting proteins are responsible for these functions, as in two-component systems.3","tracks":[{"project":"2_test","denotations":[{"id":"18599074-16311037-62517910","span":{"begin":253,"end":254},"obj":"16311037"},{"id":"18599074-15680762-62517911","span":{"begin":463,"end":464},"obj":"15680762"}],"attributes":[{"subj":"18599074-16311037-62517910","pred":"source","obj":"2_test"},{"subj":"18599074-15680762-62517911","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#b3ec93","default":true}]}]}}