PMC:2724631 / 5014-5558 JSONTXT

{"project":"2_test","denotations":[{"id":"19290482-14804124-63243930","span":{"begin":387,"end":388},"obj":"14804124"},{"id":"19290482-15995830-63243931","span":{"begin":540,"end":542},"obj":"15995830"}],"text":"The dissemination of parenchymal glial tumors into the leptomeninges has been recognized since the early twentieth century [8]. PDLG by contrast is a rare condition in which a glioma primarily involves the leptomeningeal space without obvious extension into the central nervous system parenchyma. The tumors likely arise from heterotopic nests of glial tissue in the subarachnoid space [9]. Patients with PDLG can present with a variety of clinical symptoms, but the most common presenting symptoms are due to raised intracranial pressure [10]."}