PMC:2700745 / 13010-13670 JSONTXT

{"project":"2_test","denotations":[{"id":"19176218-18665776-100518320","span":{"begin":179,"end":183},"obj":"18665776"},{"id":"19176218-18665776-100518320","span":{"begin":179,"end":183},"obj":"18665776"},{"id":"19176218-18617994-3579173","span":{"begin":516,"end":520},"obj":"18617994"},{"id":"19176218-18617994-3579173","span":{"begin":516,"end":520},"obj":"18617994"},{"id":"19176218-18665776-100518321","span":{"begin":654,"end":658},"obj":"18665776"},{"id":"19176218-18665776-100518321","span":{"begin":654,"end":658},"obj":"18665776"},{"id":"T91297","span":{"begin":516,"end":520},"obj":"18617994"},{"id":"T49758","span":{"begin":516,"end":520},"obj":"18617994"}],"text":"Because influenza A viruses frequently adapt to efficient transmission among pigs, these animals have occasionally been used as a model for testing vaccines (van der Laan et al., 2008). Signs of illness include fever, loss of appetite, labored breathing and coughing. However, the animals rarely die from the disease unless virus is directly inoculated into the trachea, in which case they exhibit signs of pneumonia. Pigs have been found to have low susceptibility to recently emerged H5N1 strains (Lipatov et al., 2008). To date, the main use of the pig has been in the development of vaccines against swine influenza (reviewed by van der Laan et al., 2008)."}