PMC:2678986 / 18300-18857
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2678986","sourcedb":"PMC","sourceid":"2678986","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2678986","text":"MRPs are known to co-transport drugs with glucuronide, glutathione or sulphate. Amongst the nine members of this transporter family (MRP1–9), the first five (MRP-1, MRP-2, MRP-3, MRP-4 and MRP-5) are frequently associated with the efflux of therapeutic agents. MRP-1, MRP-2 and MRP-3, transport hydrophilic anionic compounds, large molecules and peptidomimetics (Dallas et al., 2006); however, both MRP-4 and MRP-5 transport small polar compounds such as nucleosides, cyclic nucleotides and nucleoside analogs (Schuetz et al., 1999; Wijnholds et al., 2000).","tracks":[{"project":"2_test","denotations":[{"id":"19176219-16714484-99578312","span":{"begin":378,"end":382},"obj":"16714484"},{"id":"19176219-16714484-99578312","span":{"begin":378,"end":382},"obj":"16714484"},{"id":"19176219-10470083-99578313","span":{"begin":527,"end":531},"obj":"10470083"},{"id":"19176219-10470083-99578313","span":{"begin":527,"end":531},"obj":"10470083"},{"id":"19176219-10840050-99578314","span":{"begin":551,"end":555},"obj":"10840050"},{"id":"19176219-10840050-99578314","span":{"begin":551,"end":555},"obj":"10840050"},{"id":"19176219-16714484-3576955","span":{"begin":378,"end":382},"obj":"16714484"},{"id":"19176219-16714484-3576955","span":{"begin":378,"end":382},"obj":"16714484"},{"id":"19176219-10470083-3576956","span":{"begin":551,"end":555},"obj":"10470083"},{"id":"19176219-10470083-3576956","span":{"begin":551,"end":555},"obj":"10470083"},{"id":"19176219-10840050-3576956","span":{"begin":551,"end":555},"obj":"10840050"},{"id":"19176219-10840050-3576956","span":{"begin":551,"end":555},"obj":"10840050"}],"attributes":[{"subj":"19176219-16714484-99578312","pred":"source","obj":"2_test"},{"subj":"19176219-16714484-99578312","pred":"source","obj":"2_test"},{"subj":"19176219-10470083-99578313","pred":"source","obj":"2_test"},{"subj":"19176219-10470083-99578313","pred":"source","obj":"2_test"},{"subj":"19176219-10840050-99578314","pred":"source","obj":"2_test"},{"subj":"19176219-10840050-99578314","pred":"source","obj":"2_test"},{"subj":"19176219-16714484-3576955","pred":"source","obj":"2_test"},{"subj":"19176219-16714484-3576955","pred":"source","obj":"2_test"},{"subj":"19176219-10470083-3576956","pred":"source","obj":"2_test"},{"subj":"19176219-10470083-3576956","pred":"source","obj":"2_test"},{"subj":"19176219-10840050-3576956","pred":"source","obj":"2_test"},{"subj":"19176219-10840050-3576956","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ecc993","default":true}]}]}}