PMC:2675008 / 7517-11389
Annnotations
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Group differences analysed using Kruskal–Wallis nonparametric ANOVA and Mann–Whitney U test\nControl group elective caesarean (n = 26) Total fluids given until birth Kruskal–Wallis P value Mann–Whitney P value\nFluid group 1 \u003c1000 ml (n = 113) Fluid group 2 1000–2500 ml (n = 87) Fluid group 3 \u003e2500 ml (n = 61)\nMedian Q1–Q3 Median Q1–Q3 Median Q1–Q3 Median Q1–Q3\nMother\nAge 32 27–35 31 28–34 30 27–33 30 26–33 0.117\nWeight before pregnancy (kg) 67 58–78 66 59–73 67 60–77 66 60–77 0.750\nBody mass index before pregnancy 26.2 22.6–28.1 23.7 21.0–25.5 24.1 21.5–27.9 23.9 22.1–27.1 0.066\nWeight at term (kg) 83 72–89 79 71–89 80 74–90 83 74–91 0.399\nWeight increase 12 10–18 13 11–16 14 10–17 15 11–19 0.466\nGestational weeks 38.5 38.3–38.7 39.7 39.0–40.6 40.0 39.1–40.9 40.3 39.6–41.0 0.087\nCervical dilatation at admission (cm) — — 5.0 4.0–7.0 4.0 3.0–4.0 3.0 2.0–4.0 \u003c0.001 \u003c0.001\nDuration of labour (hours) — — 1.6 0.9–3.0 5.9 4.3–8.9 12.2 9.8–14.7 \u003c0.001 \u003c0.001\nDuration second stage (hours) — — 0.2 0.1–0.5 0.5 0.2–1.0 0.6 0.4–1.0 \u003c0.001 \u003c0.001\nOral fluids (ml/hour) 0 0–0 185 79–316 196 136–305 196 154–263 0.429\nIntravenous fluid (ml/hour) Not measured Not measured 0 0–0 52 3–102 94 53–144 \u003c0.001 \u003c0.001\nTotal fluid (ml/hour) Not measured Not measured 194 100–325 291 201–362 314 260–360 \u003c0.001 \u003c0.001\nTotal fluid (ml) Not measured Not measured 400 200–575 1680 1355–2050 3570 2925–4355 —\nOxytocin (ml) — — 0 0–0 50 0–166 200 100–400 \u003c0.001 \u003c0.001\nOxytocin (units) — — 0.0 0.0–0.0 1.0 0.0–3.3 4.0 2.0–8.0 \u003c0.001 \u003c0.001\nOxytocin (maximum rate mU/minute)* — — 10 5–20 20 10–30 40 20–60 \u003c0.001 \u003c0.001\nDuration epidural (hours) — — 1.7 1.7–1.7 4.3 2.9–6.1 8.8 6.8–10.6 —\nOsmolality at baseline (mOsm/kg) 279 277–281 280 277–282 280 276–282 279 277–281 0.501\nOsmolality postpartum (mOsm/kg) 280 277–282 282 279–284 277 276–281 274 272–277 \u003c0.001 \u003c0.001**\nNa at baseline (mmol/l) 137 136–138 137 136–137 136 135–137 136 135–138 0.238\nNa postpartum (mmol/l) 137 137–138 136 135–137 135 133–136 133 130–135 \u003c0.001 \u003c0.001**\nNa change (mmol/l) 0.0 −1.0 to 1.0 0.0 −1.0 to 1.0 −2.0 −3.0 to −1.0 −3.0 −5.0 to −1.0 \u003c0.001 \u003c0.001**\nGlucose at baseline (mmol/l) 5.0 4.5–5.5 5.1 4.7–5.8 5.2 4.9–5.9 5.3 4.8–6.2 0.133\nGlucose postpartum (mmol/l) 4.8 4.2–5.1 6.7 5.9–7.9 7.7 6.5–9.4 7.8 6.9–9.4 \u003c0.001 \u003c0.001**\nUmbilical cord\nArterial BE −2.0 −3.0 to −1.0 −4.0 −6.0 to −3.0 −5.0 −7.0 to −3.0 −6.0 −9.0 to −3.0 \u003c0.001 0.006**\nArterial pH 7.27 7.24–7.29 7.26 7.22–7.31 7.24 7.19–7.29 7.24 7.17–7.29 0.042 0.014***\nArterial Na (mmol/l) 139 138–140 139 137–140 137 136–139 136 134–138 \u003c0.001 \u003c0.001**\nArterial–venous Na difference (mmol/l) 1.0 0.0–1.0 1.0 0.0–2.0 1.0 0.0–2.0 1.0 0.0–2.0 0.736\nArterial glucose (mmol/l) 3.4 3.0–3.7 4.2 3.6–5.0 5.2 4.2–6.1 5.4 4.7–6.6 \u003c0.001 \u003c0.001**\nInfant\nBirthweight (g) 3415 3120–3790 3535 3305–3850 3670 3360–4160 3805 3580–4040 0.001 0.001**\nAll group differences are compared with Kruskal–Wallis nonparametric analysis of variance (ANOVA). When significant differences are found, Mann–Whitney U test is performed to analyse differences between fluid groups 1 and 3.\n* Including only subjects who received oxytocin. Maximum rate mU/minute: maximum rate of oxytocin infusion during first stage of labour.\n** Differences between control group elective caesarean and fluid group 3: P \u003c 0.001 (Mann–Whitney) (additional significant test).\n*** Difference between control group elective caesarean and fluid group 3: P = 0.14 (Mann–Whitney) (additional significant 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