
PMC:2674207 / 34386-34744
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11327 | 0-9 | NN | denotes | Treatment |
T11328 | 10-14 | IN | denotes | with |
T11329 | 15-17 | NN | denotes | FP |
T11330 | 18-20 | FW | denotes | ex |
T11331 | 21-25 | FW | denotes | vivo |
T11332 | 26-38 | VB | denotes | demonstrated |
T11333 | 39-40 | DT | denotes | a |
T11334 | 41-64 | JJ | denotes | concentration-dependent |
T11335 | 65-73 | NN | denotes | decrease |
T11336 | 74-76 | IN | denotes | in |
T11337 | 77-80 | DT | denotes | the |
T11338 | 81-87 | JJ | denotes | direct |
T11339 | 88-99 | NN | denotes | interaction |
T11340 | 100-107 | IN | denotes | between |
T11341 | 108-122 | NN | denotes | phospho-GATA-3 |
T11342 | 123-126 | CC | denotes | and |
T11343 | 127-137 | NN | denotes | importin-α |
T11344 | 138-140 | IN | denotes | in |
T11345 | 141-146 | NN | denotes | PBMCs |
T11346 | 147-151 | IN | denotes | from |
T11347 | 152-160 | NN | denotes | patients |
T11348 | 161-165 | IN | denotes | with |
T11349 | 166-172 | NN | denotes | asthma |
T11350 | 173-174 | -LRB- | denotes | ( |
T11351 | 174-180 | NN | denotes | Figure |
T11352 | 181-183 | NN | denotes | 6A |
T11353 | 184-187 | CC | denotes | and |
T11354 | 188-190 | NN | denotes | 6B |
T11355 | 190-191 | -RRB- | denotes | ) |
T11356 | 191-192 | -COMMA- | denotes | , |
T11357 | 193-198 | WDT | denotes | which |
T11358 | 199-202 | VB | denotes | was |
T11359 | 203-216 | RB | denotes | significantly |
T11360 | 217-226 | VB | denotes | inhibited |
T11361 | 227-229 | IN | denotes | at |
T11362 | 230-235 | CD | denotes | 10−12 |
T11363 | 236-237 | NN | denotes | M |
T11364 | 238-240 | NN | denotes | FP |
T11365 | 241-242 | -LRB- | denotes | ( |
T11366 | 242-243 | NN | denotes | p |
T11367 | 243-244 | JJ | denotes | < |
T11368 | 244-249 | CD | denotes | 0.001 |
T11369 | 249-250 | -COMMA- | denotes | , |
T11370 | 251-256 | NN | denotes | ANOVA |
T11371 | 257-260 | CC | denotes | and |
T11372 | 261-273 | NNP | denotes | Newman-Keuls |
T11373 | 274-278 | NN | denotes | test |
T11374 | 278-279 | -RRB- | denotes | ) |
T11375 | 280-283 | CC | denotes | and |
T11376 | 284-294 | RB | denotes | completely |
T11377 | 295-305 | VB | denotes | attenuated |
T11378 | 306-308 | IN | denotes | by |
T11379 | 309-313 | CD | denotes | 10−8 |
T11380 | 314-315 | NN | denotes | M |
T11381 | 316-318 | NN | denotes | FP |
T11382 | 319-320 | -LRB- | denotes | ( |
T11383 | 320-321 | NN | denotes | p |
T11384 | 321-322 | JJ | denotes | < |
T11385 | 322-327 | CD | denotes | 0.001 |
T11386 | 327-328 | -COMMA- | denotes | , |
T11387 | 329-334 | NN | denotes | ANOVA |
T11388 | 335-338 | CC | denotes | and |
T11389 | 339-351 | NNP | denotes | Newman-Keuls |
T11390 | 352-356 | NN | denotes | test |
T11391 | 356-357 | -RRB- | denotes | ) |
R9662 | T11327 | T11328 | arg1Of | Treatment,with |
R9663 | T11327 | T11332 | arg1Of | Treatment,demonstrated |
R9664 | T11329 | T11328 | arg2Of | FP,with |
R9665 | T11329 | T11331 | arg1Of | FP,vivo |
R9666 | T11331 | T11330 | arg1Of | vivo,ex |
R9667 | T11335 | T11332 | arg2Of | decrease,demonstrated |
R9668 | T11335 | T11333 | arg1Of | decrease,a |
R9669 | T11335 | T11334 | arg1Of | decrease,concentration-dependent |
R9670 | T11335 | T11336 | arg1Of | decrease,in |
R9671 | T11339 | T11336 | arg2Of | interaction,in |
R9672 | T11339 | T11337 | arg1Of | interaction,the |
R9673 | T11339 | T11338 | arg1Of | interaction,direct |
R9674 | T11339 | T11340 | arg1Of | interaction,between |
R9675 | T11341 | T11342 | arg1Of | phospho-GATA-3,and |
R9676 | T11342 | T11340 | arg2Of | and,between |
R9677 | T11342 | T11344 | arg1Of | and,in |
R9678 | T11342 | T11356 | arg1Of | and,"," |
R9679 | T11342 | T11357 | arg1Of | and,which |
R9680 | T11342 | T11358 | arg1Of | and,was |
R9681 | T11342 | T11360 | arg2Of | and,inhibited |
R9682 | T11342 | T11377 | arg2Of | and,attenuated |
R9683 | T11343 | T11342 | arg2Of | importin-α,and |
R9684 | T11345 | T11344 | arg2Of | PBMCs,in |
R9685 | T11345 | T11346 | arg1Of | PBMCs,from |
R9686 | T11347 | T11346 | arg2Of | patients,from |
R9687 | T11347 | T11348 | arg1Of | patients,with |
R9688 | T11347 | T11350 | arg1Of | patients,( |
R9689 | T11349 | T11348 | arg2Of | asthma,with |
R9690 | T11352 | T11351 | arg1Of | 6A,Figure |
R9691 | T11352 | T11353 | arg1Of | 6A,and |
R9692 | T11353 | T11350 | arg2Of | and,( |
R9693 | T11354 | T11353 | arg2Of | 6B,and |
R9694 | T11355 | T11350 | arg3Of | ),( |
R9695 | T11360 | T11361 | arg1Of | inhibited,at |
R9696 | T11360 | T11375 | arg1Of | inhibited,and |
R9697 | T11362 | T11363 | arg1Of | 10−12,M |
R9698 | T11364 | T11361 | arg2Of | FP,at |
R9699 | T11364 | T11362 | arg1Of | FP,10−12 |
R9700 | T11364 | T11365 | arg1Of | FP,( |
R9701 | T11366 | T11365 | arg2Of | p,( |
R9702 | T11366 | T11367 | arg1Of | p,< |
R9703 | T11366 | T11369 | arg1Of | p,"," |
R9704 | T11367 | T11368 | arg1Of | <,0.001 |
R9705 | T11370 | T11371 | arg1Of | ANOVA,and |
R9706 | T11371 | T11369 | arg2Of | and,"," |
R9707 | T11373 | T11371 | arg2Of | test,and |
R9708 | T11373 | T11372 | arg1Of | test,Newman-Keuls |
R9709 | T11374 | T11365 | arg3Of | ),( |
R9710 | T11375 | T11358 | arg2Of | and,was |
R9711 | T11375 | T11359 | arg1Of | and,significantly |
R9712 | T11377 | T11375 | arg2Of | attenuated,and |
R9713 | T11377 | T11376 | arg1Of | attenuated,completely |
R9714 | T11379 | T11380 | arg1Of | 10−8,M |
R9715 | T11381 | T11377 | arg1Of | FP,attenuated |
R9716 | T11381 | T11378 | arg2Of | FP,by |
R9717 | T11381 | T11379 | arg1Of | FP,10−8 |
R9718 | T11381 | T11382 | arg1Of | FP,( |
R9719 | T11383 | T11382 | arg2Of | p,( |
R9720 | T11383 | T11384 | arg1Of | p,< |
R9721 | T11383 | T11386 | arg1Of | p,"," |
R9722 | T11384 | T11385 | arg1Of | <,0.001 |
R9723 | T11387 | T11388 | arg1Of | ANOVA,and |
R9724 | T11388 | T11386 | arg2Of | and,"," |
R9725 | T11390 | T11388 | arg2Of | test,and |
R9726 | T11390 | T11389 | arg1Of | test,Newman-Keuls |
R9727 | T11391 | T11382 | arg3Of | ),( |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11940 | 0-9 | NNP | denotes | Treatment |
T11941 | 10-14 | IN | denotes | with |
T11942 | 15-17 | NNP | denotes | FP |
T11943 | 18-20 | FW | denotes | ex |
T11944 | 21-25 | FW | denotes | vivo |
T11945 | 26-38 | VBD | denotes | demonstrated |
T11946 | 39-40 | DT | denotes | a |
T11947 | 41-64 | JJ | denotes | concentration-dependent |
T11948 | 65-73 | NN | denotes | decrease |
T11949 | 74-76 | IN | denotes | in |
T11950 | 77-80 | DT | denotes | the |
T11951 | 81-87 | JJ | denotes | direct |
T11952 | 88-99 | NN | denotes | interaction |
T11953 | 100-107 | IN | denotes | between |
T11954 | 108-122 | JJ | denotes | phospho-GATA-3 |
T11955 | 123-126 | CC | denotes | and |
T11956 | 127-137 | JJ | denotes | importin-α |
T11957 | 138-140 | IN | denotes | in |
T11958 | 141-146 | NNS | denotes | PBMCs |
T11959 | 147-151 | IN | denotes | from |
T11960 | 152-160 | NNS | denotes | patients |
T11961 | 161-165 | IN | denotes | with |
T11962 | 166-172 | NN | denotes | asthma |
T11963 | 173-174 | -LRB- | denotes | ( |
T11964 | 174-180 | NN | denotes | Figure |
T11965 | 181-183 | NN | denotes | 6A |
T11966 | 184-187 | CC | denotes | and |
T11967 | 188-190 | NN | denotes | 6B |
T11968 | 190-191 | -RRB- | denotes | ) |
T11969 | 191-192 | , | denotes | , |
T11970 | 193-198 | WDT | denotes | which |
T11971 | 199-202 | VBD | denotes | was |
T11972 | 203-216 | RB | denotes | significantly |
T11973 | 217-226 | VBN | denotes | inhibited |
T11974 | 227-229 | IN | denotes | at |
T11975 | 230-232 | CD | denotes | 10 |
T11976 | 232-233 | CD | denotes | − |
T11977 | 233-235 | CD | denotes | 12 |
T11978 | 236-237 | NNP | denotes | M |
T11979 | 238-240 | NNP | denotes | FP |
T11980 | 241-242 | -LRB- | denotes | ( |
T11981 | 242-243 | FW | denotes | p |
T11982 | 243-244 | FW | denotes | < |
T11983 | 244-249 | CD | denotes | 0.001 |
T11984 | 249-250 | , | denotes | , |
T11985 | 251-256 | NNP | denotes | ANOVA |
T11986 | 257-260 | CC | denotes | and |
T11987 | 261-273 | NNP | denotes | Newman-Keuls |
T11988 | 274-278 | NN | denotes | test |
T11989 | 278-279 | -RRB- | denotes | ) |
T11990 | 280-283 | CC | denotes | and |
T11991 | 284-294 | RB | denotes | completely |
T11992 | 295-305 | VBN | denotes | attenuated |
T11993 | 306-308 | IN | denotes | by |
T11994 | 309-311 | CD | denotes | 10 |
T11995 | 311-312 | NN | denotes | − |
T11996 | 312-313 | CD | denotes | 8 |
T11997 | 314-315 | NNP | denotes | M |
T11998 | 316-318 | NNP | denotes | FP |
T11999 | 319-320 | -LRB- | denotes | ( |
T12000 | 320-321 | FW | denotes | p |
T12001 | 321-322 | FW | denotes | < |
T12002 | 322-327 | CD | denotes | 0.001 |
T12003 | 327-328 | , | denotes | , |
T12004 | 329-334 | NNP | denotes | ANOVA |
T12005 | 335-338 | CC | denotes | and |
T12006 | 339-351 | NNP | denotes | Newman-Keuls |
T12007 | 352-356 | NN | denotes | test |
T12008 | 356-357 | -RRB- | denotes | ) |
T12009 | 357-358 | . | denotes | . |
R10256 | T11943 | T11944 | nmod | ex,vivo |
R10257 | T11944 | T11945 | nsubj | vivo,demonstrated |
R10258 | T11945 | T11945 | ROOT | demonstrated,demonstrated |
R10259 | T11946 | T11948 | det | a,decrease |
R10260 | T11947 | T11948 | amod | concentration-dependent,decrease |
R10261 | T11948 | T11945 | dobj | decrease,demonstrated |
R10262 | T11949 | T11948 | prep | in,decrease |
R10263 | T11950 | T11952 | det | the,interaction |
R10264 | T11951 | T11952 | amod | direct,interaction |
R10265 | T11952 | T11949 | pobj | interaction,in |
R10266 | T11953 | T11952 | prep | between,interaction |
R10267 | T11954 | T11953 | pobj | phospho-GATA-3,between |
R10268 | T11955 | T11954 | cc | and,phospho-GATA-3 |
R10269 | T11956 | T11954 | conj | importin-α,phospho-GATA-3 |
R10270 | T11957 | T11956 | prep | in,importin-α |
R10271 | T11958 | T11957 | pobj | PBMCs,in |
R10272 | T11959 | T11954 | prep | from,phospho-GATA-3 |
R10273 | T11960 | T11959 | pobj | patients,from |
R10274 | T11961 | T11960 | prep | with,patients |
R10275 | T11962 | T11965 | compound | asthma,6A |
R10276 | T11963 | T11964 | punct | (,Figure |
R10277 | T11964 | T11965 | compound | Figure,6A |
R10278 | T11965 | T11961 | pobj | 6A,with |
R10279 | T11966 | T11965 | cc | and,6A |
R10280 | T11967 | T11965 | conj | 6B,6A |
R10281 | T11968 | T11967 | punct | ),6B |
R10282 | T11969 | T11965 | punct | ",",6A |
R10283 | T11970 | T11973 | nsubjpass | which,inhibited |
R10284 | T11971 | T11973 | auxpass | was,inhibited |
R10285 | T11972 | T11973 | advmod | significantly,inhibited |
R10286 | T11973 | T11960 | relcl | inhibited,patients |
R10287 | T11974 | T11973 | prep | at,inhibited |
R10288 | T11975 | T11979 | nummod | 10,FP |
R10289 | T11976 | T11979 | nummod | −,FP |
R10290 | T11977 | T11979 | nummod | 12,FP |
R10291 | T11978 | T11979 | compound | M,FP |
R10292 | T11979 | T11974 | pobj | FP,at |
R10293 | T11980 | T11979 | punct | (,FP |
R10294 | T11981 | T11982 | nmod | p,< |
R10295 | T11982 | T11983 | nmod | <,0.001 |
R10296 | T11983 | T11979 | appos | 0.001,FP |
R10297 | T11984 | T11983 | punct | ",",0.001 |
R10298 | T11985 | T11983 | conj | ANOVA,0.001 |
R10299 | T11986 | T11985 | cc | and,ANOVA |
R10300 | T11987 | T11988 | compound | Newman-Keuls,test |
R10301 | T11988 | T11985 | conj | test,ANOVA |
R10302 | T11989 | T11988 | punct | ),test |
R10303 | T11990 | T11973 | cc | and,inhibited |
R10304 | T11991 | T11992 | advmod | completely,attenuated |
R10305 | T11992 | T11973 | conj | attenuated,inhibited |
R10306 | T11993 | T11992 | prep | by,attenuated |
R10307 | T11994 | T11998 | nummod | 10,FP |
R10308 | T11995 | T11996 | quantmod | −,8 |
R10309 | T11996 | T11998 | nummod | 8,FP |
R10310 | T11997 | T11998 | compound | M,FP |
R10311 | T11998 | T12001 | nmod | FP,< |
R10312 | T11999 | T12001 | punct | (,< |
R10313 | T12000 | T12001 | nmod | p,< |
R10314 | T12001 | T11993 | pobj | <,by |
R10315 | T12002 | T12001 | appos | 0.001,< |
R10316 | T12003 | T12001 | punct | ",",< |
R10317 | T12004 | T12001 | conj | ANOVA,< |
R10318 | T12005 | T12004 | cc | and,ANOVA |
R10319 | T12006 | T12007 | compound | Newman-Keuls,test |
R10320 | T12007 | T12004 | conj | test,ANOVA |
R10321 | T12008 | T12001 | punct | ),< |
R10322 | T12009 | T11945 | punct | .,demonstrated |
R10254 | T11941 | T11940 | prep | with,Treatment |
R10255 | T11942 | T11944 | compound | FP,vivo |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11292 | 0-358 | Sentence | denotes | Treatment with FP ex vivo demonstrated a concentration-dependent decrease in the direct interaction between phospho-GATA-3 and importin-α in PBMCs from patients with asthma (Figure 6A and 6B), which was significantly inhibited at 10−12 M FP (p<0.001, ANOVA and Newman-Keuls test) and completely attenuated by 10−8 M FP (p<0.001, ANOVA and Newman-Keuls test). |
T233 | 0-358 | Sentence | denotes | Treatment with FP ex vivo demonstrated a concentration-dependent decrease in the direct interaction between phospho-GATA-3 and importin-α in PBMCs from patients with asthma (Figure 6A and 6B), which was significantly inhibited at 10−12 M FP (p<0.001, ANOVA and Newman-Keuls test) and completely attenuated by 10−8 M FP (p<0.001, ANOVA and Newman-Keuls test). |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12585 | 166-172 | http://purl.bioontology.org/ontology/ICD10/J45.9 | denotes | asthma |
T12587 | 166-172 | http://purl.bioontology.org/ontology/ICD10/J45 | denotes | asthma |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12735 | 55-64 | Regulation | denotes | dependent |
T12736 | 65-73 | Negative_regulation | denotes | decrease |
T12737 | 88-99 | Binding | denotes | interaction |
T12738 | 108-115 | Phosphorylation | denotes | phospho |
T12739 | 116-122 | Protein | denotes | GATA-3 |
T12740 | 217-226 | Negative_regulation | denotes | inhibited |
T12741 | 295-305 | Negative_regulation | denotes | attenuated |
R10970 | T12736 | T12735 | themeOf | decrease,dependent |
R10971 | T12737 | T12736 | themeOf | interaction,decrease |
R10972 | T12737 | T12740 | themeOf | interaction,inhibited |
R10973 | T12737 | T12741 | themeOf | interaction,attenuated |
R10974 | T12739 | T12737 | themeOf | GATA-3,interaction |
R10975 | T12739 | T12738 | themeOf | GATA-3,phospho |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12798 | 108-122 | Protein | denotes | phospho-GATA-3 |
T12799 | 127-137 | Protein | denotes | importin-α |
T12800 | 88-99 | Binding | denotes | interaction |
T12801 | 65-73 | Negative_regulation | denotes | decrease |
R11016 | T12798 | T12800 | themeOf | phospho-GATA-3,interaction |
R11017 | T12799 | T12800 | themeOf | importin-α,interaction |
R11018 | T12800 | T12801 | themeOf | interaction,decrease |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11228 | 55-64 | Regulation | denotes | dependent |
T11229 | 65-73 | Negative_regulation | denotes | decrease |
T11230 | 88-99 | Binding | denotes | interaction |
T11231 | 108-115 | Phosphorylation | denotes | phospho |
T11232 | 116-122 | Protein | denotes | GATA-3 |
T11233 | 217-226 | Negative_regulation | denotes | inhibited |
T11234 | 295-305 | Negative_regulation | denotes | attenuated |
R9599 | T11229 | T11228 | themeOf | decrease,dependent |
R9600 | T11230 | T11229 | themeOf | interaction,decrease |
R9601 | T11230 | T11233 | themeOf | interaction,inhibited |
R9602 | T11230 | T11234 | themeOf | interaction,attenuated |
R9603 | T11232 | T11230 | themeOf | GATA-3,interaction |
R9604 | T11232 | T11231 | themeOf | GATA-3,phospho |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11897 | 116-122 | P23771 | denotes | GATA-3 |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11164 | 55-64 | Regulation | denotes | dependent |
T11165 | 65-73 | Negative_regulation | denotes | decrease |
T11166 | 88-99 | Binding | denotes | interaction |
T11167 | 108-115 | Phosphorylation | denotes | phospho |
T11168 | 116-122 | Protein | denotes | GATA-3 |
T11169 | 217-226 | Negative_regulation | denotes | inhibited |
T11170 | 295-305 | Negative_regulation | denotes | attenuated |
R9551 | T11166 | T11165 | themeOf | interaction,decrease |
R9552 | T11166 | T11170 | themeOf | interaction,attenuated |
R9553 | T11166 | T11169 | themeOf | interaction,inhibited |
R9554 | T11167 | T11170 | themeOf | phospho,attenuated |
R9555 | T11167 | T11169 | themeOf | phospho,inhibited |
R9556 | T11168 | T11166 | themeOf | GATA-3,interaction |
R9557 | T11168 | T11167 | themeOf | GATA-3,phospho |