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2_test

Id Subject Object Predicate Lexical cue
19436703-12876556-86274493 180-182 12876556 denotes 32
19436703-17277157-86274494 440-442 17277157 denotes 12
19436703-11140432-86274495 782-784 11140432 denotes 37
T38523 180-182 12876556 denotes 32
T73484 440-442 17277157 denotes 12
T58090 782-784 11140432 denotes 37

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T8245 0-3 DT denotes The
T8246 4-10 NN denotes Effect
T8247 11-13 IN denotes of
T8248 14-29 NN denotes Corticosteroids
T8249 30-32 IN denotes on
T8250 33-39 NN denotes GATA-3
T8251 40-47 JJ denotes Nuclear
T8252 48-61 NN denotes Translocation
T8253 62-65 CC denotes and
T8254 66-70 NN denotes IL-4
T8255 71-75 NN denotes mRNA
T8256 76-91 NN denotes Corticosteroids
T8257 92-95 VB denotes are
T8258 96-105 JJ denotes effective
T8259 106-108 IN denotes in
T8260 109-119 VB denotes inhibiting
T8261 120-136 JJ denotes GATA-3-regulated
T8262 137-141 NN denotes IL-4
T8263 142-146 NN denotes gene
T8264 147-157 NN denotes expression
T8265 158-160 FW denotes in
T8266 161-166 FW denotes vitro
T8267 167-170 CC denotes and
T8268 171-173 FW denotes in
T8269 174-178 FW denotes vivo
T8270 179-180 -LRB- denotes [
T8271 180-182 CD denotes 32
T8272 182-183 -RRB- denotes ]
T8273 185-187 PRP denotes We
T8274 188-197 RB denotes therefore
T8275 198-210 VB denotes investigated
T8276 211-218 IN denotes whether
T8277 219-234 NN denotes corticosteroids
T8278 235-241 VB denotes affect
T8279 242-266 JJ denotes anti-CD3/CD28–stimulated
T8280 267-274 JJ denotes nuclear
T8281 275-281 NN denotes import
T8282 282-284 IN denotes of
T8283 285-291 NN denotes GATA-3
T8284 293-304 NN denotes Stimulation
T8285 305-307 IN denotes of
T8286 308-313 NN denotes cells
T8287 314-318 IN denotes with
T8288 319-332 NN denotes anti-CD3/CD28
T8289 333-341 VB denotes resulted
T8290 342-344 IN denotes in
T8291 345-346 DT denotes a
T8292 347-352 JJ denotes rapid
T8293 353-372 JJ denotes cytoplasmic/nuclear
T8294 373-379 NN denotes GATA-3
T8295 380-393 NN denotes translocation
T8296 394-395 -LRB- denotes (
T8297 395-401 NN denotes Figure
T8298 402-404 NN denotes 1A
T8299 404-405 -RRB- denotes )
T8300 405-406 -COMMA- denotes ,
T8301 407-417 VB denotes confirming
T8302 418-421 PRP-DOLLAR- denotes our
T8303 422-430 JJ denotes previous
T8304 431-438 NN denotes results
T8305 439-440 -LRB- denotes [
T8306 440-442 CD denotes 12
T8307 442-443 -RRB- denotes ]
T8308 445-447 PRP denotes We
T8309 448-452 RB denotes also
T8310 453-462 VB denotes confirmed
T8311 463-464 DT denotes a
T8312 465-470 JJ denotes clear
T8313 471-481 NN denotes separation
T8314 482-484 IN denotes of
T8315 485-492 JJ denotes nuclear
T8316 493-496 CC denotes and
T8317 497-506 JJ denotes cytosolic
T8318 507-516 NN denotes fractions
T8319 517-519 IN denotes as
T8320 520-529 VB denotes indicated
T8321 530-532 IN denotes by
T8322 533-540 NN denotes histone
T8323 541-543 NN denotes H1
T8324 544-547 CC denotes and
T8325 548-553 NN denotes MEK-1
T8326 554-561 NN denotes markers
T8327 562-563 -LRB- denotes (
T8328 563-569 NN denotes Figure
T8329 570-572 NN denotes 1B
T8330 572-573 -RRB- denotes )
T8331 575-578 DT denotes The
T8332 579-585 JJ denotes potent
T8333 586-593 JJ denotes topical
T8334 594-608 NN denotes corticosteroid
T8335 609-611 NN denotes FP
T8336 612-618 VB denotes caused
T8337 619-628 JJ denotes sustained
T8338 629-633 NN denotes loss
T8339 634-636 IN denotes of
T8340 637-644 JJ denotes nuclear
T8341 645-651 NN denotes GATA-3
T8342 652-662 NN denotes expression
T8343 663-666 CC denotes and
T8344 667-678 JJ denotes cytoplasmic
T8345 679-688 NN denotes retention
T8346 689-691 IN denotes of
T8347 692-698 NN denotes GATA-3
T8348 699-701 IN denotes at
T8349 702-716 NN denotes concentrations
T8350 717-724 VB denotes ranging
T8351 725-729 IN denotes from
T8352 730-735 CD denotes 10−12
T8353 736-738 TO denotes to
T8354 739-743 CD denotes 10−8
T8355 744-745 NN denotes M
T8356 745-746 -COMMA- denotes ,
T8357 747-752 WDT denotes which
T8358 753-758 VB denotes cover
T8359 759-762 DT denotes the
T8360 763-774 JJ denotes therapeutic
T8361 775-780 NN denotes range
T8362 781-782 -LRB- denotes [
T8363 782-784 CD denotes 37
T8364 784-785 -RRB- denotes ]
T8365 787-791 DT denotes This
T8366 792-798 NN denotes effect
T8367 799-802 VB denotes was
T8368 803-817 NN denotes concentration-
T8369 818-821 CC denotes and
T8370 822-836 JJ denotes time-dependent
T8371 836-837 -COMMA- denotes ,
T8372 838-842 IN denotes with
T8373 843-844 DT denotes a
T8374 845-849 JJ denotes peak
T8375 850-856 NN denotes effect
T8376 857-859 IN denotes of
T8377 860-869 RB denotes 11.6-fold
T8378 870-872 IN denotes at
T8379 873-875 CD denotes 30
T8380 876-879 NN denotes min
T8381 880-882 IN denotes at
T8382 883-884 DT denotes a
T8383 885-898 NN denotes concentration
T8384 899-901 IN denotes of
T8385 902-906 CD denotes 10−8
T8386 907-908 NN denotes M
T8387 909-910 -LRB- denotes (
T8388 910-916 NN denotes Figure
T8389 917-919 NN denotes 1C
T8390 919-920 -RRB- denotes )
T8391 921-924 CC denotes and
T8392 925-928 VB denotes was
T8393 929-939 VB denotes associated
T8394 940-944 IN denotes with
T8395 945-951 JJ denotes marked
T8396 952-962 NN denotes reductions
T8397 963-965 IN denotes in
T8398 966-990 JJ denotes anti-CD3/CD28–stimulated
T8399 991-995 NN denotes IL-4
T8400 996-999 CC denotes and
T8401 1000-1004 NN denotes IL-5
T8402 1005-1009 NN denotes mRNA
T8403 1010-1020 NN denotes expression
T8404 1021-1022 -LRB- denotes (
T8405 1022-1028 NN denotes Figure
T8406 1029-1031 NN denotes 1D
T8407 1031-1032 -RRB- denotes )
T8408 1033-1036 CC denotes and
T8409 1037-1038 DT denotes a
T8410 1039-1043 NN denotes loss
T8411 1044-1046 IN denotes of
T8412 1047-1053 NN denotes GATA-3
T8413 1054-1061 NN denotes binding
T8414 1062-1064 TO denotes to
T8415 1065-1068 DT denotes the
T8416 1069-1075 JJ denotes native
T8417 1076-1080 NN denotes IL-5
T8418 1081-1089 NN denotes promoter
T8419 1090-1091 -LRB- denotes (
T8420 1091-1097 NN denotes Figure
T8421 1098-1100 NN denotes 1E
T8422 1100-1101 -RRB- denotes )
T16038 1147-1158 NN denotes Fluticasone
T16039 1159-1169 NN denotes propionate
T16040 1170-1184 VB denotes down-regulates
T16041 1185-1188 NN denotes Th2
T16042 1189-1197 NN denotes cytokine
T16043 1198-1202 NN denotes gene
T16044 1203-1213 NN denotes expression
T16045 1214-1217 CC denotes and
T16046 1218-1226 VB denotes inhibits
T16047 1227-1233 NN denotes GATA-3
T16048 1234-1241 JJ denotes nuclear
T16049 1242-1248 NN denotes import
T16050 1250-1251 -LRB- denotes (
T16051 1251-1252 NN denotes A
T16052 1252-1253 -RRB- denotes )
T16053 1254-1267 JJ denotes Anti-CD3/CD28
T16054 1268-1277 NN denotes treatment
T16055 1278-1280 IN denotes of
T16056 1281-1287 NN denotes HuT-78
T16057 1288-1293 NN denotes cells
T16058 1294-1301 VB denotes results
T16059 1302-1304 IN denotes in
T16060 1305-1318 NN denotes translocation
T16061 1319-1321 IN denotes of
T16062 1322-1328 NN denotes GATA-3
T16063 1329-1333 IN denotes from
T16064 1334-1337 DT denotes the
T16065 1338-1347 NN denotes cytoplasm
T16066 1348-1350 TO denotes to
T16067 1351-1354 DT denotes the
T16068 1355-1362 NN denotes nucleus
T16069 1363-1369 IN denotes within
T16070 1370-1372 CD denotes 30
T16071 1373-1377 NN denotes min.
T16072 1378-1379 -LRB- denotes (
T16073 1379-1380 NN denotes B
T16074 1380-1381 -RRB- denotes )
T16075 1382-1389 NN denotes Histone
T16076 1390-1392 NN denotes H1
T16077 1393-1396 CC denotes and
T16078 1397-1402 NN denotes MEK-1
T16079 1403-1407 VB denotes were
T16080 1408-1412 VB denotes used
T16081 1413-1415 TO denotes to
T16082 1416-1423 VB denotes confirm
T16083 1424-1432 JJ denotes distinct
T16084 1433-1443 NN denotes separation
T16085 1444-1446 IN denotes of
T16086 1447-1458 JJ denotes cytoplasmic
T16087 1459-1462 CC denotes and
T16088 1463-1470 JJ denotes nuclear
T16089 1471-1479 NN denotes extracts
T16090 1480-1482 IN denotes in
T16091 1483-1488 CD denotes three
T16092 1489-1497 JJ denotes separate
T16093 1498-1510 NN denotes experiments.
T16094 1511-1512 -LRB- denotes (
T16095 1512-1513 NN denotes C
T16096 1513-1514 -RRB- denotes )
T16097 1515-1522 JJ denotes Western
T16098 1523-1527 NN denotes blot
T16099 1528-1536 NN denotes analysis
T16100 1537-1539 IN denotes of
T16101 1540-1550 JJ denotes FP-treated
T16102 1551-1557 NN denotes HuT-78
T16103 1558-1563 NN denotes cells
T16104 1564-1576 VB denotes demonstrated
T16105 1577-1585 JJ denotes impaired
T16106 1586-1593 JJ denotes nuclear
T16107 1594-1606 NN denotes localization
T16108 1607-1609 IN denotes of
T16109 1610-1616 NN denotes GATA-3
T16110 1617-1624 VB denotes induced
T16111 1625-1627 IN denotes by
T16112 1628-1641 JJ denotes anti-CD3/CD28
T16113 1642-1656 NN denotes co-stimulation
T16114 1657-1659 IN denotes in
T16115 1660-1661 DT denotes a
T16116 1662-1667 NN denotes time-
T16117 1668-1669 -LRB- denotes (
T16118 1669-1671 IN denotes at
T16119 1672-1676 CD denotes 10−8
T16120 1677-1678 NN denotes M
T16121 1679-1681 NN denotes FP
T16122 1681-1682 -RRB- denotes )
T16123 1683-1686 CC denotes and
T16124 1687-1701 NN denotes concentration-
T16125 1702-1703 -LRB- denotes (
T16126 1703-1705 IN denotes at
T16127 1706-1708 CD denotes 60
T16128 1709-1712 NN denotes min
T16129 1713-1718 IN denotes after
T16130 1719-1730 NN denotes stimulation
T16131 1730-1731 -RRB- denotes )
T16132 1732-1741 JJ denotes dependent
T16133 1742-1748 NN denotes manner
T16134 1750-1755 NN denotes Cells
T16135 1756-1760 VB denotes were
T16136 1761-1771 VB denotes pretreated
T16137 1772-1776 IN denotes with
T16138 1777-1779 NN denotes FP
T16139 1780-1783 IN denotes for
T16140 1784-1786 CD denotes 30
T16141 1787-1790 NN denotes min
T16142 1791-1796 JJ denotes prior
T16143 1797-1799 TO denotes to
T16144 1800-1811 NN denotes stimulation
T16145 1813-1817 NN denotes MEK1
T16146 1818-1821 CC denotes and
T16147 1822-1829 NN denotes histone
T16148 1830-1832 NN denotes H1
T16149 1833-1837 VB denotes were
T16150 1838-1842 VB denotes used
T16151 1843-1845 TO denotes to
T16152 1846-1857 VB denotes demonstrate
T16153 1858-1863 JJ denotes equal
T16154 1864-1875 JJ denotes cytoplasmic
T16155 1876-1879 CC denotes and
T16156 1880-1887 JJ denotes nuclear
T16157 1888-1895 NN denotes loading
T16158 1896-1908 RB denotes respectively
T16159 1910-1917 NN denotes Results
T16160 1918-1921 VB denotes are
T16161 1922-1931 VB denotes presented
T16162 1932-1943 RB denotes graphically
T16163 1944-1949 IN denotes below
T16164 1950-1952 IN denotes as
T16165 1953-1961 NN denotes mean±SEM
T16166 1962-1964 IN denotes of
T16167 1965-1967 IN denotes at
T16168 1968-1973 JJ denotes least
T16169 1974-1979 CD denotes three
T16170 1980-1991 JJ denotes independent
T16171 1992-2004 NN denotes experiments.
T16172 2005-2008 SYM denotes ***
T16173 2009-2010 NN denotes p
T16174 2010-2011 SYM denotes <
T16175 2011-2016 CD denotes 0.001
T16176 2017-2025 VB denotes compared
T16177 2026-2028 TO denotes to
T16178 2029-2035 NN denotes t = 0.
T16179 2036-2037 -LRB- denotes (
T16180 2037-2038 NN denotes D
T16181 2038-2039 -RRB- denotes )
T16182 2040-2046 NN denotes RT-PCR
T16183 2047-2054 VB denotes showing
T16184 2055-2059 IN denotes that
T16185 2060-2062 NN denotes FP
T16186 2063-2071 VB denotes inhibits
T16187 2072-2076 NN denotes IL-4
T16188 2077-2080 CC denotes and
T16189 2081-2085 NN denotes IL-5
T16190 2086-2090 NN denotes mRNA
T16191 2091-2101 NN denotes expression
T16192 2102-2104 IN denotes in
T16193 2105-2126 JJ denotes CD3/CD28-costimulated
T16194 2127-2132 NN denotes cells
T16195 2134-2139 NN denotes GAPDH
T16196 2140-2143 VB denotes was
T16197 2144-2148 VB denotes used
T16198 2149-2151 IN denotes as
T16199 2152-2153 DT denotes a
T16200 2154-2161 NN denotes loading
T16201 2162-2169 NN denotes control
T16202 2171-2176 JJ denotes Lower
T16203 2177-2183 NN denotes panels
T16204 2184-2188 VB denotes show
T16205 2189-2198 JJ denotes graphical
T16206 2199-2207 NN denotes analysis
T16207 2208-2210 IN denotes of
T16208 2211-2218 NN denotes results
T16209 2219-2228 VB denotes presented
T16210 2229-2231 IN denotes as
T16211 2232-2240 NN denotes mean±SEM
T16212 2241-2243 IN denotes of
T16213 2244-2246 IN denotes at
T16214 2247-2252 JJ denotes least
T16215 2253-2258 CD denotes three
T16216 2259-2270 JJ denotes independent
T16217 2271-2283 NN denotes experiments.
T16218 2284-2285 -SHARP- denotes #
T16219 2285-2286 -SHARP- denotes #
T16220 2286-2287 -SHARP- denotes #
T16221 2009-2010 NN denotes p
T16222 2010-2011 SYM denotes <
T16223 2011-2016 CD denotes 0.001
T16224 2017-2025 VB denotes compared
T16225 2026-2028 TO denotes to
T16226 2308-2315 NN denotes control
T16227 2315-2316 -COMMA- denotes ,
T16228 2317-2321 NN denotes ***p
T16229 2321-2322 SYM denotes <
T16230 2322-2327 CD denotes 0.001
T16231 2328-2336 VB denotes compared
T16232 2337-2339 TO denotes to
T16233 2340-2365 JJ denotes anti-CD3/CD28–stimulated.
T16234 2366-2367 -LRB- denotes (
T16235 2367-2368 NN denotes E
T16236 2368-2369 -RRB- denotes )
T16237 2370-2372 NN denotes FP
T16238 2373-2374 -LRB- denotes (
T16239 2374-2376 CD denotes 10
T16240 2377-2379 NN denotes nM
T16241 2379-2380 -RRB- denotes )
T16242 2381-2388 VB denotes reduces
T16243 2389-2392 DT denotes the
T16244 2393-2400 NN denotes ability
T16245 2401-2403 IN denotes of
T16246 2404-2428 JJ denotes anti-CD3/CD28-stimulated
T16247 2429-2435 NN denotes GATA-3
T16248 2436-2438 TO denotes to
T16249 2439-2448 VB denotes associate
T16250 2449-2453 IN denotes with
T16251 2454-2457 DT denotes the
T16252 2458-2464 JJ denotes native
T16253 2465-2469 NN denotes IL-5
T16254 2470-2478 NN denotes promoter
T16255 2479-2481 CD denotes 60
T16256 2482-2485 NN denotes min
T16257 2486-2491 IN denotes after
T16258 2492-2503 NN denotes stimulation
T16259 2505-2509 NN denotes Data
T16260 2510-2513 VB denotes are
T16261 2514-2518 RB denotes also
T16262 2519-2524 VB denotes shown
T16263 2525-2536 RB denotes graphically
T16264 2537-2539 IN denotes as
T16265 2540-2548 NN denotes mean±SEM
T16266 2549-2551 IN denotes of
T16267 2552-2557 CD denotes three
T16268 2558-2569 JJ denotes independent
T16269 2570-2581 NN denotes experiments
T16270 2583-2586 DT denotes All
T16271 2587-2591 NN denotes data
T16272 2592-2596 VB denotes were
T16273 2597-2605 VB denotes analysed
T16274 2606-2608 IN denotes by
T16275 2609-2614 NN denotes ANOVA
T16276 2615-2623 VB denotes followed
T16277 2624-2626 IN denotes by
T16278 2627-2639 NN denotes Newman-Keuls
T16279 2640-2649 JJ denotes post-test
T17018 2009-2010 NN denotes p
T17019 2010-2011 SYM denotes <
T17020 2011-2016 CD denotes 0.001
T17021 2017-2025 VB denotes compared
T17022 2026-2028 TO denotes to
T17023 2308-2315 NN denotes control
T17024 2315-2316 -COMMA- denotes ,
T17025 2317-2321 NN denotes ***p
T17026 2321-2322 SYM denotes <
T17027 2322-2327 CD denotes 0.001
T17028 2328-2336 VB denotes compared
T17029 2337-2339 TO denotes to
T17743 2009-2010 NN denotes p
T17744 2010-2011 SYM denotes <
T17745 2011-2016 CD denotes 0.001
T17746 2017-2025 VB denotes compared
T17747 2026-2028 TO denotes to
T17748 2308-2315 NN denotes control
T17749 2315-2316 -COMMA- denotes ,
T17750 2317-2321 NN denotes ***p
T17751 2321-2322 SYM denotes <
T17752 2322-2327 CD denotes 0.001
T17753 2328-2336 VB denotes compared
T17754 2337-2339 TO denotes to
T18776 2320-2321 NN denotes p
T18777 2321-2322 SYM denotes <
T18778 2322-2327 CD denotes 0.001
T18779 2328-2336 VB denotes compared
T18780 2337-2339 TO denotes to
T18781 2340-2364 JJ denotes anti-CD3/CD28–stimulated
R7117 T8246 T8245 arg1Of Effect,The
R7118 T8246 T8247 arg1Of Effect,of
R7119 T8246 T8249 arg1Of Effect,on
R7120 T8248 T8247 arg2Of Corticosteroids,of
R7121 T8252 T8250 arg1Of Translocation,GATA-3
R7122 T8252 T8251 arg1Of Translocation,Nuclear
R7123 T8252 T8253 arg1Of Translocation,and
R7124 T8253 T8249 arg2Of and,on
R7125 T8255 T8253 arg2Of mRNA,and
R7126 T8255 T8254 arg1Of mRNA,IL-4
R7127 T8256 T8257 arg1Of Corticosteroids,are
R7128 T8256 T8258 arg1Of Corticosteroids,effective
R7129 T8258 T8257 arg2Of effective,are
R7130 T8258 T8259 arg1Of effective,in
R7131 T8260 T8259 arg2Of inhibiting,in
R7132 T8260 T8270 arg1Of inhibiting,[
R7133 T8264 T8260 arg2Of expression,inhibiting
R7134 T8264 T8261 arg1Of expression,GATA-3-regulated
R7135 T8264 T8262 arg1Of expression,IL-4
R7136 T8264 T8263 arg1Of expression,gene
R7137 T8264 T8266 arg1Of expression,vitro
R7138 T8264 T8269 arg1Of expression,vivo
R7139 T8266 T8265 arg1Of vitro,in
R7140 T8266 T8267 arg1Of vitro,and
R7141 T8269 T8267 arg2Of vivo,and
R7142 T8269 T8268 arg1Of vivo,in
R7143 T8271 T8270 arg2Of 32,[
R7144 T8272 T8270 arg3Of ],[
R7145 T8273 T8275 arg1Of We,investigated
R7146 T8275 T8274 arg1Of investigated,therefore
R7147 T8277 T8278 arg1Of corticosteroids,affect
R7148 T8278 T8275 arg2Of affect,investigated
R7149 T8278 T8276 arg1Of affect,whether
R7150 T8281 T8278 arg2Of import,affect
R7151 T8281 T8279 arg1Of import,anti-CD3/CD28–stimulated
R7152 T8281 T8280 arg1Of import,nuclear
R7153 T8281 T8282 arg1Of import,of
R7154 T8283 T8282 arg2Of GATA-3,of
R7155 T8284 T8285 arg1Of Stimulation,of
R7156 T8284 T8287 arg1Of Stimulation,with
R7157 T8284 T8289 arg1Of Stimulation,resulted
R7158 T8286 T8285 arg2Of cells,of
R7159 T8288 T8287 arg2Of anti-CD3/CD28,with
R7160 T8289 T8290 arg1Of resulted,in
R7161 T8289 T8300 arg1Of resulted,","
R7162 T8289 T8301 modOf resulted,confirming
R7163 T8289 T8305 arg1Of resulted,[
R7164 T8295 T8290 arg2Of translocation,in
R7165 T8295 T8291 arg1Of translocation,a
R7166 T8295 T8292 arg1Of translocation,rapid
R7167 T8295 T8293 arg1Of translocation,cytoplasmic/nuclear
R7168 T8295 T8294 arg1Of translocation,GATA-3
R7169 T8295 T8296 arg1Of translocation,(
R7170 T8298 T8296 arg2Of 1A,(
R7171 T8298 T8297 arg1Of 1A,Figure
R7172 T8299 T8296 arg3Of ),(
R7173 T8304 T8301 arg2Of results,confirming
R7174 T8304 T8302 arg1Of results,our
R7175 T8304 T8303 arg1Of results,previous
R7176 T8306 T8305 arg2Of 12,[
R7177 T8307 T8305 arg3Of ],[
R7178 T8308 T8310 arg1Of We,confirmed
R7179 T8310 T8309 arg1Of confirmed,also
R7180 T8310 T8319 arg1Of confirmed,as
R7181 T8313 T8310 arg2Of separation,confirmed
R7182 T8313 T8311 arg1Of separation,a
R7183 T8313 T8312 arg1Of separation,clear
R7184 T8313 T8314 arg1Of separation,of
R7185 T8315 T8316 arg1Of nuclear,and
R7186 T8317 T8316 arg2Of cytosolic,and
R7187 T8318 T8314 arg2Of fractions,of
R7188 T8318 T8315 arg1Of fractions,nuclear
R7189 T8318 T8317 arg1Of fractions,cytosolic
R7190 T8320 T8319 arg2Of indicated,as
R7191 T8323 T8322 arg1Of H1,histone
R7192 T8323 T8324 arg1Of H1,and
R7193 T8324 T8320 arg1Of and,indicated
R7194 T8324 T8321 arg2Of and,by
R7195 T8326 T8324 arg2Of markers,and
R7196 T8326 T8325 arg1Of markers,MEK-1
R7197 T8326 T8327 arg1Of markers,(
R7198 T8329 T8327 arg2Of 1B,(
R7199 T8329 T8328 arg1Of 1B,Figure
R7200 T8330 T8327 arg3Of ),(
R7201 T8335 T8331 arg1Of FP,The
R7202 T8335 T8332 arg1Of FP,potent
R7203 T8335 T8333 arg1Of FP,topical
R7204 T8335 T8334 arg1Of FP,corticosteroid
R7205 T8335 T8336 arg1Of FP,caused
R7206 T8338 T8336 arg2Of loss,caused
R7207 T8338 T8337 arg1Of loss,sustained
R7208 T8338 T8339 arg1Of loss,of
R7209 T8342 T8340 arg1Of expression,nuclear
R7210 T8342 T8341 arg1Of expression,GATA-3
R7211 T8342 T8343 arg1Of expression,and
R7212 T8343 T8339 arg2Of and,of
R7213 T8343 T8348 arg1Of and,at
R7214 T8345 T8343 arg2Of retention,and
R7215 T8345 T8344 arg1Of retention,cytoplasmic
R7216 T8345 T8346 arg1Of retention,of
R7217 T8347 T8346 arg2Of GATA-3,of
R7218 T8349 T8348 arg2Of concentrations,at
R7219 T8349 T8350 arg1Of concentrations,ranging
R7220 T8350 T8351 arg1Of ranging,from
R7221 T8352 T8353 arg1Of 10−12,to
R7222 T8354 T8353 arg2Of 10−8,to
R7223 T8355 T8351 arg2Of M,from
R7224 T8355 T8352 arg1Of M,10−12
R7225 T8355 T8356 arg1Of M,","
R7226 T8355 T8357 arg1Of M,which
R7227 T8355 T8358 arg1Of M,cover
R7228 T8361 T8358 arg2Of range,cover
R7229 T8361 T8359 arg1Of range,the
R7230 T8361 T8360 arg1Of range,therapeutic
R7231 T8361 T8362 arg1Of range,[
R7232 T8363 T8362 arg2Of 37,[
R7233 T8364 T8362 arg3Of ],[
R7234 T8366 T8365 arg1Of effect,This
R7235 T8366 T8367 arg1Of effect,was
R7236 T8366 T8368 arg1Of effect,concentration-
R7237 T8366 T8370 arg1Of effect,time-dependent
R7238 T8366 T8392 arg1Of effect,was
R7239 T8366 T8393 arg2Of effect,associated
R7240 T8367 T8371 arg1Of was,","
R7241 T8367 T8372 arg1Of was,with
R7242 T8367 T8391 arg1Of was,and
R7243 T8368 T8369 arg1Of concentration-,and
R7244 T8369 T8367 arg2Of and,was
R7245 T8370 T8369 arg2Of time-dependent,and
R7246 T8375 T8372 arg2Of effect,with
R7247 T8375 T8373 arg1Of effect,a
R7248 T8375 T8374 arg1Of effect,peak
R7249 T8375 T8376 arg1Of effect,of
R7250 T8375 T8381 arg1Of effect,at
R7251 T8379 T8377 arg1Of 30,11.6-fold
R7252 T8379 T8378 arg1Of 30,at
R7253 T8380 T8376 arg2Of min,of
R7254 T8380 T8379 arg1Of min,30
R7255 T8383 T8381 arg2Of concentration,at
R7256 T8383 T8382 arg1Of concentration,a
R7257 T8383 T8384 arg1Of concentration,of
R7258 T8386 T8384 arg2Of M,of
R7259 T8386 T8385 arg1Of M,10−8
R7260 T8386 T8387 arg1Of M,(
R7261 T8389 T8387 arg2Of 1C,(
R7262 T8389 T8388 arg1Of 1C,Figure
R7263 T8390 T8387 arg3Of ),(
R7264 T8393 T8391 arg2Of associated,and
R7265 T8393 T8392 arg2Of associated,was
R7266 T8393 T8394 arg1Of associated,with
R7267 T8396 T8394 arg2Of reductions,with
R7268 T8396 T8395 arg1Of reductions,marked
R7269 T8396 T8397 arg1Of reductions,in
R7270 T8399 T8400 arg1Of IL-4,and
R7271 T8401 T8400 arg2Of IL-5,and
R7272 T8403 T8398 arg1Of expression,anti-CD3/CD28–stimulated
R7273 T8403 T8399 arg1Of expression,IL-4
R7274 T8403 T8401 arg1Of expression,IL-5
R7275 T8403 T8402 arg1Of expression,mRNA
R7276 T8403 T8404 arg1Of expression,(
R7277 T8403 T8408 arg1Of expression,and
R7278 T8406 T8404 arg2Of 1D,(
R7279 T8406 T8405 arg1Of 1D,Figure
R7280 T8407 T8404 arg3Of ),(
R7281 T8408 T8397 arg2Of and,in
R7282 T8410 T8408 arg2Of loss,and
R7283 T8410 T8409 arg1Of loss,a
R7284 T8410 T8411 arg1Of loss,of
R7285 T8410 T8414 arg1Of loss,to
R7286 T8413 T8411 arg2Of binding,of
R7287 T8413 T8412 arg1Of binding,GATA-3
R7288 T8418 T8414 arg2Of promoter,to
R7289 T8418 T8415 arg1Of promoter,the
R7290 T8418 T8416 arg1Of promoter,native
R7291 T8418 T8417 arg1Of promoter,IL-5
R7292 T8418 T8419 arg1Of promoter,(
R7293 T8421 T8419 arg2Of 1E,(
R7294 T8421 T8420 arg1Of 1E,Figure
R7295 T8422 T8419 arg3Of ),(
R13756 T16039 T16038 arg1Of propionate,Fluticasone
R13757 T16039 T16040 arg1Of propionate,down-regulates
R13758 T16039 T16046 arg1Of propionate,inhibits
R13759 T16040 T16045 arg1Of down-regulates,and
R13760 T16044 T16040 arg2Of expression,down-regulates
R13761 T16044 T16041 arg1Of expression,Th2
R13762 T16044 T16042 arg1Of expression,cytokine
R13763 T16044 T16043 arg1Of expression,gene
R13764 T16046 T16045 arg2Of inhibits,and
R13765 T16049 T16046 arg2Of import,inhibits
R13766 T16049 T16047 arg1Of import,GATA-3
R13767 T16049 T16048 arg1Of import,nuclear
R13768 T16051 T16050 arg2Of A,(
R13769 T16052 T16050 arg3Of ),(
R13770 T16054 T16050 arg1Of treatment,(
R13771 T16054 T16053 arg1Of treatment,Anti-CD3/CD28
R13772 T16054 T16055 arg1Of treatment,of
R13773 T16054 T16058 arg1Of treatment,results
R13774 T16057 T16055 arg2Of cells,of
R13775 T16057 T16056 arg1Of cells,HuT-78
R13776 T16058 T16059 arg1Of results,in
R13777 T16058 T16066 arg1Of results,to
R13778 T16058 T16069 arg1Of results,within
R13779 T16058 T16077 arg1Of results,and
R13780 T16060 T16059 arg2Of translocation,in
R13781 T16060 T16061 arg1Of translocation,of
R13782 T16062 T16061 arg2Of GATA-3,of
R13783 T16062 T16063 arg1Of GATA-3,from
R13784 T16065 T16063 arg2Of cytoplasm,from
R13785 T16065 T16064 arg1Of cytoplasm,the
R13786 T16068 T16066 arg2Of nucleus,to
R13787 T16068 T16067 arg1Of nucleus,the
R13788 T16071 T16070 arg1Of min.,30
R13789 T16071 T16072 arg1Of min.,(
R13790 T16073 T16072 arg2Of B,(
R13791 T16074 T16072 arg3Of ),(
R13792 T16076 T16069 arg2Of H1,within
R13793 T16076 T16071 arg1Of H1,min.
R13794 T16076 T16075 arg1Of H1,Histone
R13795 T16078 T16079 arg1Of MEK-1,were
R13796 T16078 T16080 arg2Of MEK-1,used
R13797 T16080 T16077 arg2Of used,and
R13798 T16080 T16079 arg2Of used,were
R13799 T16082 T16080 arg3Of confirm,used
R13800 T16082 T16081 arg1Of confirm,to
R13801 T16084 T16082 arg2Of separation,confirm
R13802 T16084 T16083 arg1Of separation,distinct
R13803 T16084 T16085 arg1Of separation,of
R13804 T16084 T16090 arg1Of separation,in
R13805 T16084 T16104 modOf separation,demonstrated
R13806 T16086 T16087 arg1Of cytoplasmic,and
R13807 T16088 T16087 arg2Of nuclear,and
R13808 T16089 T16085 arg2Of extracts,of
R13809 T16089 T16086 arg1Of extracts,cytoplasmic
R13810 T16089 T16088 arg1Of extracts,nuclear
R13811 T16093 T16090 arg2Of experiments.,in
R13812 T16093 T16091 arg1Of experiments.,three
R13813 T16093 T16092 arg1Of experiments.,separate
R13814 T16093 T16094 arg1Of experiments.,(
R13815 T16095 T16094 arg2Of C,(
R13816 T16096 T16094 arg3Of ),(
R13817 T16099 T16097 arg1Of analysis,Western
R13818 T16099 T16098 arg1Of analysis,blot
R13819 T16099 T16100 arg1Of analysis,of
R13820 T16099 T16104 arg1Of analysis,demonstrated
R13821 T16103 T16100 arg2Of cells,of
R13822 T16103 T16101 arg1Of cells,FP-treated
R13823 T16103 T16102 arg1Of cells,HuT-78
R13824 T16106 T16105 arg1Of nuclear,impaired
R13825 T16107 T16104 arg2Of localization,demonstrated
R13826 T16107 T16106 arg1Of localization,nuclear
R13827 T16107 T16108 arg1Of localization,of
R13828 T16109 T16108 arg2Of GATA-3,of
R13829 T16109 T16110 arg2Of GATA-3,induced
R13830 T16113 T16112 arg1Of co-stimulation,anti-CD3/CD28
R13831 T16113 T16114 arg1Of co-stimulation,in
R13832 T16113 T16123 arg1Of co-stimulation,and
R13833 T16116 T16114 arg2Of time-,in
R13834 T16116 T16115 arg1Of time-,a
R13835 T16116 T16117 arg1Of time-,(
R13836 T16118 T16117 arg2Of at,(
R13837 T16119 T16120 arg1Of 10−8,M
R13838 T16121 T16118 arg2Of FP,at
R13839 T16121 T16119 arg1Of FP,10−8
R13840 T16122 T16117 arg3Of ),(
R13841 T16123 T16110 arg1Of and,induced
R13842 T16123 T16111 arg2Of and,by
R13843 T16124 T16125 arg1Of concentration-,(
R13844 T16126 T16125 arg2Of at,(
R13845 T16128 T16126 arg2Of min,at
R13846 T16128 T16127 arg1Of min,60
R13847 T16128 T16129 arg1Of min,after
R13848 T16130 T16129 arg2Of stimulation,after
R13849 T16131 T16125 arg3Of ),(
R13850 T16133 T16123 arg2Of manner,and
R13851 T16133 T16124 arg1Of manner,concentration-
R13852 T16133 T16132 arg1Of manner,dependent
R13853 T16134 T16135 arg1Of Cells,were
R13854 T16134 T16136 arg2Of Cells,pretreated
R13855 T16136 T16135 arg2Of pretreated,were
R13856 T16136 T16137 arg1Of pretreated,with
R13857 T16138 T16137 arg2Of FP,with
R13858 T16138 T16139 arg1Of FP,for
R13859 T16141 T16139 arg2Of min,for
R13860 T16141 T16140 arg1Of min,30
R13861 T16141 T16142 arg1Of min,prior
R13862 T16142 T16143 arg1Of prior,to
R13863 T16144 T16143 arg2Of stimulation,to
R13864 T16145 T16146 arg1Of MEK1,and
R13865 T16146 T16149 arg1Of and,were
R13866 T16146 T16150 arg2Of and,used
R13867 T16148 T16146 arg2Of H1,and
R13868 T16148 T16147 arg1Of H1,histone
R13869 T16150 T16149 arg2Of used,were
R13870 T16152 T16150 arg3Of demonstrate,used
R13871 T16152 T16151 arg1Of demonstrate,to
R13872 T16152 T16158 arg1Of demonstrate,respectively
R13873 T16154 T16155 arg1Of cytoplasmic,and
R13874 T16156 T16155 arg2Of nuclear,and
R13875 T16157 T16152 arg2Of loading,demonstrate
R13876 T16157 T16153 arg1Of loading,equal
R13877 T16157 T16154 arg1Of loading,cytoplasmic
R13878 T16157 T16156 arg1Of loading,nuclear
R13879 T16159 T16160 arg1Of Results,are
R13880 T16159 T16161 arg2Of Results,presented
R13881 T16161 T16160 arg2Of presented,are
R13882 T16161 T16163 arg1Of presented,below
R13883 T16161 T16164 arg1Of presented,as
R13884 T16161 T16176 arg1Of presented,compared
R13885 T16163 T16162 arg1Of below,graphically
R13886 T16165 T16164 arg2Of mean±SEM,as
R13887 T16165 T16166 arg1Of mean±SEM,of
R13888 T16169 T16167 arg1Of three,at
R13889 T16169 T16168 arg1Of three,least
R13890 T16171 T16166 arg2Of experiments.,of
R13891 T16171 T16169 arg1Of experiments.,three
R13892 T16171 T16170 arg1Of experiments.,independent
R13893 T16173 T16164 arg3Of p,as
R13894 T16173 T16172 arg1Of p,***
R13895 T16173 T16174 arg1Of p,<
R13896 T16175 T16161 arg3Of 0.001,presented
R13897 T16177 T16176 arg2Of to,compared
R13898 T16180 T16179 arg2Of D,(
R13899 T16181 T16179 arg3Of ),(
R13900 T16182 T16177 arg2Of RT-PCR,to
R13901 T16182 T16178 arg1Of RT-PCR,t = 0.
R13902 T16182 T16179 arg1Of RT-PCR,(
R13903 T16182 T16183 arg1Of RT-PCR,showing
R13904 T16185 T16186 arg1Of FP,inhibits
R13905 T16186 T16183 arg2Of inhibits,showing
R13906 T16186 T16184 arg1Of inhibits,that
R13907 T16187 T16188 arg1Of IL-4,and
R13908 T16189 T16188 arg2Of IL-5,and
R13909 T16191 T16186 arg2Of expression,inhibits
R13910 T16191 T16187 arg1Of expression,IL-4
R13911 T16191 T16189 arg1Of expression,IL-5
R13912 T16191 T16190 arg1Of expression,mRNA
R13913 T16191 T16192 arg1Of expression,in
R13914 T16194 T16192 arg2Of cells,in
R13915 T16194 T16193 arg1Of cells,CD3/CD28-costimulated
R13916 T16195 T16196 arg1Of GAPDH,was
R13917 T16195 T16197 arg2Of GAPDH,used
R13918 T16197 T16196 arg2Of used,was
R13919 T16197 T16198 arg1Of used,as
R13920 T16201 T16198 arg2Of control,as
R13921 T16201 T16199 arg1Of control,a
R13922 T16201 T16200 arg1Of control,loading
R13923 T16203 T16202 arg1Of panels,Lower
R13924 T16203 T16204 arg1Of panels,show
R13925 T16203 T16228 arg1Of panels,***p
R13926 T16204 T16227 arg1Of show,","
R13927 T16204 T16228 modOf show,***p
R13928 T16206 T16204 arg2Of analysis,show
R13929 T16206 T16205 arg1Of analysis,graphical
R13930 T16206 T16207 arg1Of analysis,of
R13931 T16208 T16207 arg2Of results,of
R13932 T16208 T16209 arg2Of results,presented
R13933 T16209 T16210 arg1Of presented,as
R13934 T16211 T16210 arg2Of mean±SEM,as
R13935 T16211 T16212 arg1Of mean±SEM,of
R13936 T16215 T16213 arg1Of three,at
R13937 T16215 T16214 arg1Of three,least
R13938 T16217 T16215 arg1Of experiments.,three
R13939 T16217 T16216 arg1Of experiments.,independent
R13940 T16221 T16217 arg1Of p,experiments.
R13941 T16221 T16218 arg1Of p,#
R13942 T16221 T16219 arg1Of p,#
R13943 T16221 T16220 arg1Of p,#
R13944 T16221 T16222 arg1Of p,<
R13945 T16223 T16212 arg2Of 0.001,of
R13946 T16223 T16221 arg1Of 0.001,p
R13947 T16223 T16224 arg1Of 0.001,compared
R13948 T16225 T16224 arg2Of to,compared
R13949 T16226 T16225 arg2Of control,to
R13950 T16230 T16231 arg1Of 0.001,compared
R13951 T16232 T16231 arg2Of to,compared
R13952 T16233 T16232 arg2Of anti-CD3/CD28–stimulated.,to
R13953 T16233 T16234 arg1Of anti-CD3/CD28–stimulated.,(
R13954 T16235 T16234 arg2Of E,(
R13955 T16236 T16234 arg3Of ),(
R13956 T16237 T16229 arg1Of FP,<
R13957 T16237 T16230 arg1Of FP,0.001
R13958 T16237 T16238 arg1Of FP,(
R13959 T16237 T16242 arg1Of FP,reduces
R13960 T16240 T16238 arg2Of nM,(
R13961 T16240 T16239 arg1Of nM,10
R13962 T16241 T16238 arg3Of ),(
R13963 T16242 T16228 arg2Of reduces,***p
R13964 T16244 T16242 arg2Of ability,reduces
R13965 T16244 T16243 arg1Of ability,the
R13966 T16244 T16245 arg1Of ability,of
R13967 T16244 T16248 modOf ability,to
R13968 T16247 T16245 arg2Of GATA-3,of
R13969 T16247 T16246 arg1Of GATA-3,anti-CD3/CD28-stimulated
R13970 T16249 T16248 arg1Of associate,to
R13971 T16249 T16250 arg1Of associate,with
R13972 T16256 T16250 arg2Of min,with
R13973 T16256 T16251 arg1Of min,the
R13974 T16256 T16252 arg1Of min,native
R13975 T16256 T16253 arg1Of min,IL-5
R13976 T16256 T16254 arg1Of min,promoter
R13977 T16256 T16255 arg1Of min,60
R13978 T16256 T16257 arg1Of min,after
R13979 T16258 T16257 arg2Of stimulation,after
R13980 T16259 T16260 arg1Of Data,are
R13981 T16259 T16262 arg2Of Data,shown
R13982 T16262 T16260 arg2Of shown,are
R13983 T16262 T16261 arg1Of shown,also
R13984 T16262 T16263 arg1Of shown,graphically
R13985 T16262 T16264 arg1Of shown,as
R13986 T16265 T16264 arg2Of mean±SEM,as
R13987 T16265 T16266 arg1Of mean±SEM,of
R13988 T16269 T16266 arg2Of experiments,of
R13989 T16269 T16267 arg1Of experiments,three
R13990 T16269 T16268 arg1Of experiments,independent
R13991 T16271 T16270 arg1Of data,All
R13992 T16271 T16272 arg1Of data,were
R13993 T16271 T16273 arg2Of data,analysed
R13994 T16273 T16272 arg2Of analysed,were
R13995 T16275 T16273 arg1Of ANOVA,analysed
R13996 T16275 T16274 arg2Of ANOVA,by
R13997 T16275 T16276 arg2Of ANOVA,followed
R13998 T16278 T16276 arg1Of Newman-Keuls,followed
R13999 T16278 T16277 arg2Of Newman-Keuls,by
R14000 T16278 T16279 arg1Of Newman-Keuls,post-test
R14602 T17018 T17019 arg1Of p,<
R14603 T17020 T17018 arg1Of 0.001,p
R14604 T17022 T17021 arg2Of to,compared
R14605 T17023 T17022 arg2Of control,to
R14606 T17027 T17028 arg1Of 0.001,compared
R14607 T17029 T17028 arg2Of to,compared
R15227 T17745 T17744 arg1Of 0.001,<
R15228 T17745 T17746 arg1Of 0.001,compared
R15229 T17747 T17746 arg2Of to,compared
R15230 T17748 T17747 arg2Of control,to
R15231 T17750 T17749 arg1Of ***p,","
R15232 T17752 T17753 arg1Of 0.001,compared
R15233 T17754 T17753 arg2Of to,compared
R16033 T18777 T18778 arg1Of <,0.001
R16034 T18777 T18779 arg1Of <,compared
R16035 T18780 T18779 arg2Of to,compared

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T8451 0-3 DT denotes The
T8452 4-10 NN denotes Effect
T8453 11-13 IN denotes of
T8454 14-29 NNS denotes Corticosteroids
T8455 30-32 IN denotes on
T8456 33-39 NNP denotes GATA-3
T8457 40-47 NNP denotes Nuclear
T8458 48-61 NNP denotes Translocation
T8459 62-65 CC denotes and
T8460 66-70 NN denotes IL-4
T8461 71-75 NNP denotes mRNA
T8462 76-91 NNP denotes Corticosteroids
T8463 92-95 VBP denotes are
T8464 96-105 JJ denotes effective
T8465 106-108 IN denotes in
T8466 109-119 VBG denotes inhibiting
T8467 120-136 JJ denotes GATA-3-regulated
T8468 137-141 NN denotes IL-4
T8469 142-146 NN denotes gene
T8470 147-157 NN denotes expression
T8471 158-160 IN denotes in
T8472 161-166 NN denotes vitro
T8473 167-170 CC denotes and
T8474 171-173 IN denotes in
T8475 174-178 NN denotes vivo
T8476 179-180 NNP denotes [
T8477 180-182 CD denotes 32
T8478 182-183 NNP denotes ]
T8479 183-184 . denotes .
T8480 185-187 PRP denotes We
T8481 188-197 RB denotes therefore
T8482 198-210 VBD denotes investigated
T8483 211-218 IN denotes whether
T8484 219-234 NNS denotes corticosteroids
T8485 235-241 VBP denotes affect
T8486 242-250 JJ denotes anti-CD3
T8487 250-251 NN denotes /
T8488 251-255 CD denotes CD28
T8489 256-266 VBD denotes stimulated
T8490 267-274 JJ denotes nuclear
T8491 275-281 NN denotes import
T8492 282-284 IN denotes of
T8493 285-291 NN denotes GATA-3
T8494 291-292 . denotes .
T8495 293-304 NN denotes Stimulation
T8496 305-307 IN denotes of
T8497 308-313 NNS denotes cells
T8498 314-318 IN denotes with
T8499 319-327 JJ denotes anti-CD3
T8500 327-328 NN denotes /
T8501 328-332 CD denotes CD28
T8502 333-341 VBD denotes resulted
T8503 342-344 IN denotes in
T8504 345-346 DT denotes a
T8505 347-352 JJ denotes rapid
T8506 353-372 NN denotes cytoplasmic/nuclear
T8507 373-379 NN denotes GATA-3
T8508 380-393 NN denotes translocation
T8509 394-395 -LRB- denotes (
T8510 395-401 NN denotes Figure
T8511 402-404 CD denotes 1A
T8512 404-405 -RRB- denotes )
T8513 405-406 , denotes ,
T8514 407-417 VBG denotes confirming
T8515 418-421 PRP$ denotes our
T8516 422-430 JJ denotes previous
T8517 431-438 NNS denotes results
T8518 439-440 NNP denotes [
T8519 440-442 CD denotes 12
T8520 442-443 NNP denotes ]
T8521 443-444 . denotes .
T8522 445-447 PRP denotes We
T8523 448-452 RB denotes also
T8524 453-462 VBD denotes confirmed
T8525 463-464 DT denotes a
T8526 465-470 JJ denotes clear
T8527 471-481 NN denotes separation
T8528 482-484 IN denotes of
T8529 485-492 JJ denotes nuclear
T8530 493-496 CC denotes and
T8531 497-506 JJ denotes cytosolic
T8532 507-516 NNS denotes fractions
T8533 517-519 IN denotes as
T8534 520-529 VBN denotes indicated
T8535 530-532 IN denotes by
T8536 533-540 NN denotes histone
T8537 541-543 CD denotes H1
T8538 544-547 CC denotes and
T8539 548-553 CD denotes MEK-1
T8540 554-561 NNS denotes markers
T8541 562-563 -LRB- denotes (
T8542 563-569 NN denotes Figure
T8543 570-572 NN denotes 1B
T8544 572-573 -RRB- denotes )
T8545 573-574 . denotes .
T8546 575-578 DT denotes The
T8547 579-585 JJ denotes potent
T8548 586-593 JJ denotes topical
T8549 594-608 JJ denotes corticosteroid
T8550 609-611 NN denotes FP
T8551 612-618 VBD denotes caused
T8552 619-628 JJ denotes sustained
T8553 629-633 NN denotes loss
T8554 634-636 IN denotes of
T8555 637-644 JJ denotes nuclear
T8556 645-651 JJ denotes GATA-3
T8557 652-662 NN denotes expression
T8558 663-666 CC denotes and
T8559 667-678 JJ denotes cytoplasmic
T8560 679-688 NN denotes retention
T8561 689-691 IN denotes of
T8562 692-698 NN denotes GATA-3
T8563 699-701 IN denotes at
T8564 702-716 NNS denotes concentrations
T8565 717-724 VBG denotes ranging
T8566 725-729 IN denotes from
T8567 730-732 CD denotes 10
T8568 732-733 CD denotes −
T8569 733-735 CD denotes 12
T8570 736-738 TO denotes to
T8571 739-741 CD denotes 10
T8572 741-742 CD denotes −
T8573 742-743 CD denotes 8
T8574 744-745 NNP denotes M
T8575 745-746 , denotes ,
T8576 747-752 WDT denotes which
T8577 753-758 VBP denotes cover
T8578 759-762 DT denotes the
T8579 763-774 JJ denotes therapeutic
T8580 775-780 NN denotes range
T8581 781-782 NNP denotes [
T8582 782-784 CD denotes 37
T8583 784-785 NNP denotes ]
T8584 785-786 . denotes .
T8585 787-791 DT denotes This
T8586 792-798 NN denotes effect
T8587 799-802 VBD denotes was
T8588 803-816 NN denotes concentration
T8589 816-817 : denotes -
T8590 818-821 CC denotes and
T8591 822-836 JJ denotes time-dependent
T8592 836-837 , denotes ,
T8593 838-842 IN denotes with
T8594 843-844 DT denotes a
T8595 845-849 JJ denotes peak
T8596 850-856 NN denotes effect
T8597 857-859 IN denotes of
T8598 860-869 JJ denotes 11.6-fold
T8599 870-872 IN denotes at
T8600 873-875 CD denotes 30
T8601 876-879 NN denotes min
T8602 880-882 IN denotes at
T8603 883-884 DT denotes a
T8604 885-898 NN denotes concentration
T8605 899-901 IN denotes of
T8606 902-904 CD denotes 10
T8607 904-905 NN denotes −
T8608 905-906 CD denotes 8
T8609 907-908 NNP denotes M
T8610 909-910 -LRB- denotes (
T8611 910-916 NNP denotes Figure
T8612 917-919 NNP denotes 1C
T8613 919-920 -RRB- denotes )
T8614 921-924 CC denotes and
T8615 925-928 VBD denotes was
T8616 929-939 VBN denotes associated
T8617 940-944 IN denotes with
T8618 945-951 JJ denotes marked
T8619 952-962 NNS denotes reductions
T8620 963-965 IN denotes in
T8621 966-974 JJ denotes anti-CD3
T8622 974-975 NN denotes /
T8623 975-979 CD denotes CD28
T8624 980-990 VBD denotes stimulated
T8625 991-995 NN denotes IL-4
T8626 996-999 CC denotes and
T8627 1000-1004 NN denotes IL-5
T8628 1005-1009 NNP denotes mRNA
T8629 1010-1020 NN denotes expression
T8630 1021-1022 -LRB- denotes (
T8631 1022-1028 NN denotes Figure
T8632 1029-1031 CD denotes 1D
T8633 1031-1032 -RRB- denotes )
T8634 1033-1036 CC denotes and
T8635 1037-1038 DT denotes a
T8636 1039-1043 NN denotes loss
T8637 1044-1046 IN denotes of
T8638 1047-1053 JJ denotes GATA-3
T8639 1054-1061 JJ denotes binding
T8640 1062-1064 TO denotes to
T8641 1065-1068 DT denotes the
T8642 1069-1075 JJ denotes native
T8643 1076-1080 NN denotes IL-5
T8644 1081-1089 NN denotes promoter
T8645 1090-1091 -LRB- denotes (
T8646 1091-1097 NN denotes Figure
T8647 1098-1100 CD denotes 1E
T8648 1100-1101 -RRB- denotes )
T8649 1101-1102 . denotes .
T16315 1147-1158 NNP denotes Fluticasone
T16316 1159-1169 JJ denotes propionate
T16317 1170-1184 NNS denotes down-regulates
T16318 1185-1188 JJ denotes Th2
T16319 1189-1197 NN denotes cytokine
T16320 1198-1202 NN denotes gene
T16321 1203-1213 NN denotes expression
T16322 1214-1217 CC denotes and
T16323 1218-1226 NNS denotes inhibits
T16324 1227-1233 JJ denotes GATA-3
T16325 1234-1241 JJ denotes nuclear
T16326 1242-1248 NN denotes import
T16327 1248-1249 . denotes .
T16328 1250-1251 -LRB- denotes (
T16329 1251-1252 NNP denotes A
T16330 1252-1253 -RRB- denotes )
T16331 1254-1262 JJ denotes Anti-CD3
T16332 1262-1263 NN denotes /
T16333 1263-1267 CD denotes CD28
T16334 1268-1277 NN denotes treatment
T16335 1278-1280 IN denotes of
T16336 1281-1287 JJ denotes HuT-78
T16337 1288-1293 NNS denotes cells
T16338 1294-1301 NNS denotes results
T16339 1302-1304 IN denotes in
T16340 1305-1318 NN denotes translocation
T16341 1319-1321 IN denotes of
T16342 1322-1328 NN denotes GATA-3
T16343 1329-1333 IN denotes from
T16344 1334-1337 DT denotes the
T16345 1338-1347 NN denotes cytoplasm
T16346 1348-1350 TO denotes to
T16347 1351-1354 DT denotes the
T16348 1355-1362 NN denotes nucleus
T16349 1363-1369 IN denotes within
T16350 1370-1372 CD denotes 30
T16351 1373-1376 NN denotes min
T16352 1376-1377 . denotes .
T16353 1378-1379 -LRB- denotes (
T16354 1379-1380 NNP denotes B
T16355 1380-1381 -RRB- denotes )
T16356 1382-1389 NNP denotes Histone
T16357 1390-1392 NNP denotes H1
T16358 1393-1396 CC denotes and
T16359 1397-1402 NNP denotes MEK-1
T16360 1403-1407 VBD denotes were
T16361 1408-1412 VBN denotes used
T16362 1413-1415 TO denotes to
T16363 1416-1423 VB denotes confirm
T16364 1424-1432 JJ denotes distinct
T16365 1433-1443 NN denotes separation
T16366 1444-1446 IN denotes of
T16367 1447-1458 JJ denotes cytoplasmic
T16368 1459-1462 CC denotes and
T16369 1463-1470 JJ denotes nuclear
T16370 1471-1479 NNS denotes extracts
T16371 1480-1482 IN denotes in
T16372 1483-1488 CD denotes three
T16373 1489-1497 JJ denotes separate
T16374 1498-1509 NNS denotes experiments
T16375 1509-1510 . denotes .
T16376 1511-1512 -LRB- denotes (
T16377 1512-1513 $ denotes C
T16378 1513-1514 -RRB- denotes )
T16379 1515-1522 JJ denotes Western
T16380 1523-1527 NN denotes blot
T16381 1528-1536 NN denotes analysis
T16382 1537-1539 IN denotes of
T16383 1540-1550 JJ denotes FP-treated
T16384 1551-1557 JJ denotes HuT-78
T16385 1558-1563 NNS denotes cells
T16386 1564-1576 VBD denotes demonstrated
T16387 1577-1585 VBN denotes impaired
T16388 1586-1593 JJ denotes nuclear
T16389 1594-1606 NN denotes localization
T16390 1607-1609 IN denotes of
T16391 1610-1616 JJ denotes GATA-3
T16392 1617-1624 VBN denotes induced
T16393 1625-1627 IN denotes by
T16394 1628-1636 JJ denotes anti-CD3
T16395 1636-1637 NN denotes /
T16396 1637-1641 CD denotes CD28
T16397 1642-1656 NN denotes co-stimulation
T16398 1657-1659 IN denotes in
T16399 1660-1661 DT denotes a
T16400 1662-1666 NN denotes time
T16401 1666-1667 : denotes -
T16402 1668-1669 -LRB- denotes (
T16403 1669-1671 IN denotes at
T16404 1672-1674 CD denotes 10
T16405 1674-1675 NN denotes −
T16406 1675-1676 CD denotes 8
T16407 1677-1678 NNP denotes M
T16408 1679-1681 NNP denotes FP
T16409 1681-1682 -RRB- denotes )
T16410 1683-1686 CC denotes and
T16411 1687-1700 NN denotes concentration
T16412 1700-1701 : denotes -
T16413 1702-1703 -LRB- denotes (
T16414 1703-1705 IN denotes at
T16415 1706-1708 CD denotes 60
T16416 1709-1712 NN denotes min
T16417 1713-1718 IN denotes after
T16418 1719-1730 NN denotes stimulation
T16419 1730-1731 -RRB- denotes )
T16420 1732-1741 JJ denotes dependent
T16421 1742-1748 NN denotes manner
T16422 1748-1749 . denotes .
T16423 1750-1755 NNS denotes Cells
T16424 1756-1760 VBD denotes were
T16425 1761-1771 VBN denotes pretreated
T16426 1772-1776 IN denotes with
T16427 1777-1779 NNP denotes FP
T16428 1780-1783 IN denotes for
T16429 1784-1786 CD denotes 30
T16430 1787-1790 NN denotes min
T16431 1791-1796 RB denotes prior
T16432 1797-1799 TO denotes to
T16433 1800-1811 NN denotes stimulation
T16434 1811-1812 . denotes .
T16435 1813-1817 CD denotes MEK1
T16436 1818-1821 CC denotes and
T16437 1822-1829 VB denotes histone
T16438 1830-1832 CD denotes H1
T16439 1833-1837 VBD denotes were
T16440 1838-1842 VBN denotes used
T16441 1843-1845 TO denotes to
T16442 1846-1857 VB denotes demonstrate
T16443 1858-1863 JJ denotes equal
T16444 1864-1875 JJ denotes cytoplasmic
T16445 1876-1879 CC denotes and
T16446 1880-1887 JJ denotes nuclear
T16447 1888-1895 VBG denotes loading
T16448 1896-1908 RB denotes respectively
T16449 1908-1909 . denotes .
T16450 1910-1917 NNS denotes Results
T16451 1918-1921 VBP denotes are
T16452 1922-1931 VBN denotes presented
T16453 1932-1943 RB denotes graphically
T16454 1944-1949 IN denotes below
T16455 1950-1952 IN denotes as
T16456 1953-1957 JJ denotes mean
T16457 1957-1958 NN denotes ±
T16458 1958-1961 NNP denotes SEM
T16459 1962-1964 IN denotes of
T16460 1965-1967 IN denotes at
T16461 1968-1973 JJS denotes least
T16462 1974-1979 CD denotes three
T16463 1980-1991 JJ denotes independent
T16464 1992-2003 NNS denotes experiments
T16465 2003-2004 . denotes .
T16466 2005-2008 FW denotes ***
T16467 2009-2010 FW denotes p
T16468 2010-2011 FW denotes <
T16469 2011-2016 CD denotes 0.001
T16470 2017-2025 VBN denotes compared
T16471 2026-2028 TO denotes to
T16472 2029-2030 VB denotes t
T16473 2031-2032 SYM denotes =
T16474 2033-2034 CD denotes 0
T16475 2034-2035 . denotes .
T16476 2036-2037 -LRB- denotes (
T16477 2037-2038 NNP denotes D
T16478 2038-2039 -RRB- denotes )
T16479 2040-2046 NNP denotes RT-PCR
T16480 2047-2054 VBG denotes showing
T16481 2055-2059 IN denotes that
T16482 2060-2062 NNP denotes FP
T16483 2063-2071 VBZ denotes inhibits
T16484 2072-2076 NN denotes IL-4
T16485 2077-2080 CC denotes and
T16486 2081-2085 NN denotes IL-5
T16487 2086-2090 NNP denotes mRNA
T16488 2091-2101 NN denotes expression
T16489 2102-2104 IN denotes in
T16490 2105-2126 JJ denotes CD3/CD28-costimulated
T16491 2127-2132 NNS denotes cells
T16492 2132-2133 . denotes .
T16493 2134-2139 NNP denotes GAPDH
T16494 2140-2143 VBD denotes was
T16495 2144-2148 VBN denotes used
T16496 2149-2151 IN denotes as
T16497 2152-2153 DT denotes a
T16498 2154-2161 VBG denotes loading
T16499 2162-2169 NN denotes control
T16500 2169-2170 . denotes .
T16501 2171-2176 JJR denotes Lower
T16502 2177-2183 NNS denotes panels
T16503 2184-2188 VBP denotes show
T16504 2189-2198 JJ denotes graphical
T16505 2199-2207 NN denotes analysis
T16506 2208-2210 IN denotes of
T16507 2211-2218 NNS denotes results
T16508 2219-2228 VBN denotes presented
T16509 2229-2231 IN denotes as
T16510 2232-2236 JJ denotes mean
T16511 2236-2237 NN denotes ±
T16512 2237-2240 NNP denotes SEM
T16513 2241-2243 IN denotes of
T16514 2244-2246 IN denotes at
T16515 2247-2252 JJS denotes least
T16516 2253-2258 CD denotes three
T16517 2259-2270 JJ denotes independent
T16518 2271-2282 NNS denotes experiments
T16519 2282-2283 . denotes .
T16520 2284-2287 FW denotes ###
T16521 2009-2010 FW denotes p
T16522 2010-2011 FW denotes <
T16523 2011-2016 CD denotes 0.001
T16524 2017-2025 VBN denotes compared
T16525 2026-2028 TO denotes to
T16526 2308-2315 VB denotes control
T16527 2315-2316 , denotes ,
T16528 2317-2320 FW denotes ***
T16529 2320-2321 FW denotes p
T16530 2321-2322 FW denotes <
T16531 2322-2327 CD denotes 0.001
T16532 2328-2336 VBN denotes compared
T16533 2337-2339 TO denotes to
T16534 2340-2348 JJ denotes anti-CD3
T16535 2348-2349 NN denotes /
T16536 2349-2353 CD denotes CD28
T16537 2354-2364 VBN denotes stimulated
T16538 2364-2365 . denotes .
T16539 2366-2367 -LRB- denotes (
T16540 2367-2368 NNP denotes E
T16541 2368-2369 -RRB- denotes )
T16542 2370-2372 NNP denotes FP
T16543 2373-2374 -LRB- denotes (
T16544 2374-2376 CD denotes 10
T16545 2377-2379 NNP denotes nM
T16546 2379-2380 -RRB- denotes )
T16547 2381-2388 VBZ denotes reduces
T16548 2389-2392 DT denotes the
T16549 2393-2400 NN denotes ability
T16550 2401-2403 IN denotes of
T16551 2404-2412 JJ denotes anti-CD3
T16552 2412-2413 NN denotes /
T16553 2413-2428 JJ denotes CD28-stimulated
T16554 2429-2435 NN denotes GATA-3
T16555 2436-2438 TO denotes to
T16556 2439-2448 VB denotes associate
T16557 2449-2453 IN denotes with
T16558 2454-2457 DT denotes the
T16559 2458-2464 JJ denotes native
T16560 2465-2469 NN denotes IL-5
T16561 2470-2478 NN denotes promoter
T16562 2479-2481 CD denotes 60
T16563 2482-2485 NN denotes min
T16564 2486-2491 IN denotes after
T16565 2492-2503 NN denotes stimulation
T16566 2503-2504 . denotes .
T16567 2505-2509 NNS denotes Data
T16568 2510-2513 VBP denotes are
T16569 2514-2518 RB denotes also
T16570 2519-2524 VBN denotes shown
T16571 2525-2536 RB denotes graphically
T16572 2537-2539 IN denotes as
T16573 2540-2544 JJ denotes mean
T16574 2544-2545 NN denotes ±
T16575 2545-2548 NNP denotes SEM
T16576 2549-2551 IN denotes of
T16577 2552-2557 CD denotes three
T16578 2558-2569 JJ denotes independent
T16579 2570-2581 NNS denotes experiments
T16580 2581-2582 . denotes .
T16581 2583-2586 DT denotes All
T16582 2587-2591 NNS denotes data
T16583 2592-2596 VBD denotes were
T16584 2597-2605 VBN denotes analysed
T16585 2606-2608 IN denotes by
T16586 2609-2614 NNP denotes ANOVA
T16587 2615-2623 VBD denotes followed
T16588 2624-2626 IN denotes by
T16589 2627-2639 NNP denotes Newman-Keuls
T16590 2640-2649 JJS denotes post-test
T16591 2649-2650 . denotes .
T17324 2009-2010 FW denotes p
T17325 2010-2011 FW denotes <
T17326 2011-2016 CD denotes 0.001
T17327 2017-2025 VBN denotes compared
T17328 2026-2028 TO denotes to
T17329 2308-2315 VB denotes control
T17330 2315-2316 , denotes ,
T17331 2317-2320 FW denotes ***
T17332 2320-2321 FW denotes p
T17333 2321-2322 FW denotes <
T17334 2322-2327 CD denotes 0.001
T17335 2328-2336 VBN denotes compared
T17336 2337-2339 TO denotes to
T18004 2009-2010 FW denotes p
T18005 2010-2011 FW denotes <
T18006 2011-2016 CD denotes 0.001
T18007 2017-2025 VBN denotes compared
T18008 2026-2028 TO denotes to
T18009 2308-2315 VB denotes control
T18010 2315-2316 , denotes ,
T18011 2317-2320 FW denotes ***
T18012 2320-2321 FW denotes p
T18013 2321-2322 FW denotes <
T18014 2322-2327 CD denotes 0.001
T18015 2328-2336 VBN denotes compared
T18016 2337-2339 TO denotes to
T18994 2320-2321 FW denotes p
T18995 2321-2322 FW denotes <
T18996 2322-2327 CD denotes 0.001
T18997 2328-2336 VBN denotes compared
T18998 2337-2339 TO denotes to
T18999 2340-2348 JJ denotes anti-CD3
T19000 2348-2349 NN denotes /
T19001 2349-2353 CD denotes CD28
T19002 2354-2364 VBD denotes stimulated
R7296 T8451 T8452 det The,Effect
R7297 T8452 T8463 nsubj Effect,are
R7298 T8453 T8452 prep of,Effect
R7299 T8454 T8453 pobj Corticosteroids,of
R7300 T8455 T8452 prep on,Effect
R7301 T8456 T8458 compound GATA-3,Translocation
R7302 T8457 T8458 compound Nuclear,Translocation
R7303 T8458 T8455 pobj Translocation,on
R7304 T8459 T8458 cc and,Translocation
R7305 T8460 T8462 compound IL-4,Corticosteroids
R7306 T8461 T8462 compound mRNA,Corticosteroids
R7307 T8462 T8458 conj Corticosteroids,Translocation
R7308 T8463 T8463 ROOT are,are
R7309 T8464 T8463 acomp effective,are
R7310 T8465 T8464 prep in,effective
R7311 T8466 T8465 pcomp inhibiting,in
R7312 T8467 T8470 amod GATA-3-regulated,expression
R7313 T8468 T8469 compound IL-4,gene
R7314 T8469 T8470 compound gene,expression
R7315 T8470 T8466 dobj expression,inhibiting
R7316 T8471 T8466 prep in,inhibiting
R7317 T8472 T8471 pobj vitro,in
R7318 T8473 T8471 cc and,in
R7319 T8474 T8471 conj in,in
R7320 T8475 T8474 pobj vivo,in
R7321 T8476 T8478 nmod [,]
R7322 T8477 T8478 nummod 32,]
R7323 T8478 T8463 attr ],are
R7324 T8479 T8463 punct .,are
R7325 T8480 T8482 nsubj We,investigated
R7326 T8481 T8482 advmod therefore,investigated
R7327 T8482 T8482 ROOT investigated,investigated
R7328 T8483 T8485 mark whether,affect
R7329 T8484 T8485 nsubj corticosteroids,affect
R7347 T8502 T8502 ROOT resulted,resulted
R7348 T8503 T8502 prep in,resulted
R7349 T8504 T8508 det a,translocation
R7350 T8505 T8508 amod rapid,translocation
R7351 T8506 T8508 nmod cytoplasmic/nuclear,translocation
R7352 T8507 T8508 compound GATA-3,translocation
R7353 T8508 T8503 pobj translocation,in
R7354 T8509 T8510 punct (,Figure
R7355 T8510 T8511 nmod Figure,1A
R7356 T8511 T8508 appos 1A,translocation
R7357 T8512 T8508 punct ),translocation
R7358 T8513 T8502 punct ",",resulted
R7359 T8514 T8502 advcl confirming,resulted
R7360 T8515 T8517 poss our,results
R7361 T8516 T8517 amod previous,results
R7362 T8517 T8514 dobj results,confirming
R7363 T8518 T8520 nmod [,]
R7364 T8519 T8520 nummod 12,]
R7365 T8520 T8517 appos ],results
R7366 T8521 T8502 punct .,resulted
R7367 T8522 T8524 nsubj We,confirmed
R7368 T8523 T8524 advmod also,confirmed
R7369 T8524 T8524 ROOT confirmed,confirmed
R7370 T8525 T8527 det a,separation
R7371 T8526 T8527 amod clear,separation
R7372 T8527 T8524 dobj separation,confirmed
R7373 T8528 T8527 prep of,separation
R7374 T8529 T8532 amod nuclear,fractions
R7375 T8530 T8529 cc and,nuclear
R7376 T8531 T8529 conj cytosolic,nuclear
R7377 T8532 T8528 pobj fractions,of
R7378 T8533 T8534 mark as,indicated
R7379 T8534 T8527 advcl indicated,separation
R7380 T8535 T8534 agent by,indicated
R7381 T8536 T8535 pobj histone,by
R7382 T8537 T8536 nummod H1,histone
R7383 T8538 T8536 cc and,histone
R7384 T8539 T8540 nummod MEK-1,markers
R7385 T8540 T8536 conj markers,histone
R7386 T8541 T8543 punct (,1B
R7387 T8542 T8543 compound Figure,1B
R7388 T8543 T8540 appos 1B,markers
R7389 T8544 T8543 punct ),1B
R7390 T8545 T8524 punct .,confirmed
R7391 T8546 T8550 det The,FP
R7392 T8547 T8550 amod potent,FP
R7393 T8548 T8550 amod topical,FP
R7394 T8549 T8550 amod corticosteroid,FP
R7395 T8550 T8551 nsubj FP,caused
R7396 T8551 T8551 ROOT caused,caused
R7397 T8552 T8553 amod sustained,loss
R7398 T8553 T8551 dobj loss,caused
R7399 T8554 T8553 prep of,loss
R7400 T8555 T8557 amod nuclear,expression
R7401 T8556 T8557 amod GATA-3,expression
R7402 T8557 T8554 pobj expression,of
R7403 T8558 T8557 cc and,expression
R7404 T8559 T8560 amod cytoplasmic,retention
R7405 T8560 T8557 conj retention,expression
R7406 T8561 T8557 prep of,expression
R7407 T8562 T8561 pobj GATA-3,of
R7408 T8563 T8553 prep at,loss
R7409 T8564 T8563 pobj concentrations,at
R7410 T8565 T8564 acl ranging,concentrations
R7411 T8566 T8565 prep from,ranging
R7412 T8567 T8568 nummod 10,−
R7413 T8568 T8566 pobj −,from
R7414 T8569 T8571 quantmod 12,10
R7415 T8570 T8571 quantmod to,10
R7416 T8571 T8572 nummod 10,−
R7417 T8572 T8574 nummod −,M
R7418 T8573 T8574 nummod 8,M
R7419 T8574 T8566 pobj M,from
R7420 T8575 T8574 punct ",",M
R7421 T8576 T8577 nsubj which,cover
R7422 T8577 T8574 relcl cover,M
R7423 T8578 T8580 det the,range
R7424 T8579 T8580 amod therapeutic,range
R7425 T8580 T8577 dobj range,cover
R7426 T8581 T8583 nmod [,]
R7427 T8582 T8583 nummod 37,]
R7428 T8583 T8580 appos ],range
R7429 T8584 T8551 punct .,caused
R7430 T8585 T8586 det This,effect
R7431 T8586 T8587 nsubj effect,was
R7432 T8587 T8587 ROOT was,was
R7433 T8588 T8587 attr concentration,was
R7434 T8589 T8588 punct -,concentration
R7435 T8590 T8588 cc and,concentration
R7436 T8591 T8588 conj time-dependent,concentration
R7437 T8592 T8587 punct ",",was
R7438 T8593 T8587 prep with,was
R7439 T8594 T8596 det a,effect
R7440 T8595 T8596 amod peak,effect
R7441 T8596 T8593 pobj effect,with
R7442 T8597 T8596 prep of,effect
R7443 T8598 T8597 pobj 11.6-fold,of
R7444 T8599 T8596 prep at,effect
R7445 T8600 T8601 nummod 30,min
R7446 T8601 T8599 pobj min,at
R7447 T8602 T8601 prep at,min
R7448 T8603 T8604 det a,concentration
R7449 T8604 T8602 pobj concentration,at
R7450 T8605 T8604 prep of,concentration
R7451 T8606 T8608 quantmod 10,8
R7452 T8607 T8608 quantmod −,8
R7453 T8608 T8605 pobj 8,of
R7454 T8609 T8608 quantmod M,8
R7455 T8610 T8612 punct (,1C
R7456 T8611 T8612 compound Figure,1C
R7457 T8612 T8609 appos 1C,M
R7458 T8613 T8612 punct ),1C
R7459 T8614 T8587 cc and,was
R7460 T8615 T8616 auxpass was,associated
R7461 T8616 T8624 parataxis associated,stimulated
R7462 T8617 T8616 prep with,associated
R7463 T8618 T8619 amod marked,reductions
R7464 T8619 T8617 pobj reductions,with
R7465 T8620 T8619 prep in,reductions
R7466 T8621 T8622 amod anti-CD3,/
R7467 T8622 T8620 pobj /,in
R7468 T8623 T8622 nummod CD28,/
R7469 T8624 T8587 conj stimulated,was
R7470 T8625 T8624 dobj IL-4,stimulated
R7471 T8626 T8625 cc and,IL-4
R7472 T8627 T8625 conj IL-5,IL-4
R7473 T8628 T8629 compound mRNA,expression
R7474 T8629 T8625 conj expression,IL-4
R7475 T8630 T8631 punct (,Figure
R7476 T8631 T8629 appos Figure,expression
R7477 T8632 T8631 nummod 1D,Figure
R7478 T8633 T8631 punct ),Figure
R7479 T8634 T8631 cc and,Figure
R7480 T8635 T8636 det a,loss
R7481 T8636 T8625 appos loss,IL-4
R7487 T8642 T8644 amod native,promoter
R14001 T16315 T16317 nmod Fluticasone,down-regulates
R14002 T16316 T16317 amod propionate,down-regulates
R14003 T16317 T16317 ROOT down-regulates,down-regulates
R14004 T16318 T16321 nmod Th2,expression
R14005 T16319 T16321 compound cytokine,expression
R14006 T16320 T16321 compound gene,expression
R14007 T16321 T16317 dobj expression,down-regulates
R14008 T16322 T16321 cc and,expression
R14009 T16323 T16317 conj inhibits,down-regulates
R14010 T16324 T16326 nmod GATA-3,import
R14011 T16325 T16326 amod nuclear,import
R14012 T16326 T16323 dobj import,inhibits
R14013 T16327 T16323 punct .,inhibits
R14014 T16328 T16329 punct (,A
R14015 T16329 T16329 ROOT A,A
R14016 T16330 T16329 punct ),A
R14017 T16331 T16334 amod Anti-CD3,treatment
R14018 T16332 T16334 nmod /,treatment
R14019 T16333 T16334 nummod CD28,treatment
R14020 T16334 T16334 ROOT treatment,treatment
R14021 T16335 T16334 prep of,treatment
R14022 T16336 T16337 amod HuT-78,cells
R14023 T16337 T16338 compound cells,results
R14024 T16338 T16335 pobj results,of
R14025 T16339 T16338 prep in,results
R14026 T16340 T16339 pobj translocation,in
R14027 T16341 T16340 prep of,translocation
R14028 T16342 T16341 pobj GATA-3,of
R14029 T16343 T16334 prep from,treatment
R14030 T16344 T16345 det the,cytoplasm
R14031 T16345 T16343 pobj cytoplasm,from
R14032 T16346 T16334 prep to,treatment
R14033 T16347 T16348 det the,nucleus
R14034 T16348 T16346 pobj nucleus,to
R14035 T16349 T16334 prep within,treatment
R14036 T16350 T16351 nummod 30,min
R14037 T16351 T16349 pobj min,within
R14038 T16352 T16334 punct .,treatment
R14039 T16353 T16361 punct (,used
R14040 T16354 T16361 nsubjpass B,used
R14041 T16355 T16354 punct ),B
R14042 T16356 T16357 compound Histone,H1
R14043 T16357 T16354 appos H1,B
R14044 T16358 T16357 cc and,H1
R14045 T16359 T16357 conj MEK-1,H1
R14046 T16360 T16361 auxpass were,used
R14047 T16361 T16361 ROOT used,used
R14048 T16362 T16363 aux to,confirm
R14049 T16363 T16361 xcomp confirm,used
R14050 T16364 T16365 amod distinct,separation
R14051 T16365 T16363 dobj separation,confirm
R14052 T16366 T16365 prep of,separation
R14053 T16367 T16370 amod cytoplasmic,extracts
R14054 T16368 T16367 cc and,cytoplasmic
R14055 T16369 T16367 conj nuclear,cytoplasmic
R14056 T16370 T16366 pobj extracts,of
R14057 T16371 T16363 prep in,confirm
R14058 T16372 T16374 nummod three,experiments
R14059 T16373 T16374 amod separate,experiments
R14060 T16374 T16371 pobj experiments,in
R14061 T16375 T16361 punct .,used
R14062 T16376 T16377 punct (,C
R14063 T16377 T16381 nmod C,analysis
R14064 T16378 T16377 punct ),C
R14065 T16379 T16381 amod Western,analysis
R14066 T16380 T16381 compound blot,analysis
R14067 T16381 T16386 nsubj analysis,demonstrated
R14068 T16382 T16381 prep of,analysis
R14069 T16383 T16385 amod FP-treated,cells
R14070 T16384 T16385 amod HuT-78,cells
R14071 T16385 T16382 pobj cells,of
R14072 T16386 T16386 ROOT demonstrated,demonstrated
R14073 T16387 T16389 amod impaired,localization
R14074 T16388 T16389 amod nuclear,localization
R14075 T16389 T16386 dobj localization,demonstrated
R14076 T16390 T16389 prep of,localization
R14077 T16391 T16390 pobj GATA-3,of
R14078 T16392 T16389 acl induced,localization
R14079 T16393 T16392 agent by,induced
R14080 T16394 T16397 amod anti-CD3,co-stimulation
R14081 T16395 T16397 nmod /,co-stimulation
R14082 T16396 T16397 nummod CD28,co-stimulation
R14083 T16397 T16393 pobj co-stimulation,by
R14084 T16398 T16392 prep in,induced
R14085 T16399 T16400 det a,time
R14086 T16400 T16398 pobj time,in
R14087 T16401 T16389 punct -,localization
R14088 T16402 T16389 punct (,localization
R14089 T16403 T16389 prep at,localization
R14090 T16404 T16405 nummod 10,−
R14091 T16405 T16408 nmod −,FP
R14092 T16406 T16408 nummod 8,FP
R14093 T16407 T16408 compound M,FP
R14094 T16408 T16403 pobj FP,at
R14095 T16409 T16389 punct ),localization
R14096 T16410 T16389 cc and,localization
R14097 T16411 T16389 conj concentration,localization
R14098 T16412 T16389 punct -,localization
R14099 T16413 T16389 punct (,localization
R14100 T16414 T16386 prep at,demonstrated
R14101 T16415 T16416 nummod 60,min
R14102 T16416 T16414 pobj min,at
R14103 T16417 T16416 prep after,min
R14104 T16418 T16417 pobj stimulation,after
R14105 T16419 T16386 punct ),demonstrated
R14106 T16420 T16421 amod dependent,manner
R14107 T16421 T16421 ROOT manner,manner
R14108 T16422 T16421 punct .,manner
R14109 T16423 T16425 nsubjpass Cells,pretreated
R14110 T16424 T16425 auxpass were,pretreated
R14111 T16425 T16425 ROOT pretreated,pretreated
R14112 T16426 T16425 prep with,pretreated
R14113 T16427 T16426 pobj FP,with
R14114 T16428 T16425 prep for,pretreated
R14115 T16429 T16430 nummod 30,min
R14116 T16430 T16428 pobj min,for
R14117 T16431 T16425 advmod prior,pretreated
R14118 T16432 T16431 prep to,prior
R14119 T16433 T16432 pobj stimulation,to
R14120 T16434 T16425 punct .,pretreated
R14121 T16435 T16440 nsubjpass MEK1,used
R14122 T16436 T16435 cc and,MEK1
R14123 T16437 T16438 compound histone,H1
R14124 T16438 T16435 conj H1,MEK1
R14125 T16439 T16440 auxpass were,used
R14126 T16440 T16440 ROOT used,used
R14127 T16441 T16442 aux to,demonstrate
R14128 T16442 T16440 xcomp demonstrate,used
R14129 T16443 T16444 amod equal,cytoplasmic
R14130 T16444 T16442 dobj cytoplasmic,demonstrate
R14131 T16445 T16444 cc and,cytoplasmic
R14132 T16446 T16444 conj nuclear,cytoplasmic
R14133 T16447 T16442 advcl loading,demonstrate
R14134 T16448 T16447 advmod respectively,loading
R14135 T16449 T16440 punct .,used
R14136 T16450 T16452 nsubjpass Results,presented
R14137 T16451 T16452 auxpass are,presented
R14138 T16452 T16452 ROOT presented,presented
R14139 T16453 T16454 advmod graphically,below
R14140 T16454 T16452 prep below,presented
R14141 T16455 T16452 prep as,presented
R14142 T16456 T16458 amod mean,SEM
R14143 T16457 T16458 compound ±,SEM
R14144 T16458 T16455 pobj SEM,as
R14145 T16459 T16458 prep of,SEM
R14146 T16460 T16461 advmod at,least
R14147 T16461 T16462 advmod least,three
R14148 T16462 T16464 nummod three,experiments
R14149 T16463 T16464 amod independent,experiments
R14150 T16464 T16459 pobj experiments,of
R14151 T16465 T16452 punct .,presented
R14152 T16466 T16468 compound ***,<
R14153 T16467 T16468 compound p,<
R14154 T16468 T16470 nsubj <,compared
R14155 T16469 T16468 nummod 0.001,<
R14156 T16470 T16470 ROOT compared,compared
R14157 T16471 T16470 prep to,compared
R14158 T16472 T16471 pobj t,to
R14159 T16473 T16474 punct =,0
R14160 T16474 T16472 prep 0,t
R14161 T16475 T16470 punct .,compared
R14162 T16476 T16479 punct (,RT-PCR
R14163 T16477 T16479 nmod D,RT-PCR
R14164 T16478 T16479 punct ),RT-PCR
R14165 T16479 T16479 ROOT RT-PCR,RT-PCR
R14166 T16480 T16479 acl showing,RT-PCR
R14167 T16481 T16483 mark that,inhibits
R14168 T16482 T16483 nsubj FP,inhibits
R14169 T16483 T16480 ccomp inhibits,showing
R14170 T16484 T16488 nmod IL-4,expression
R14171 T16485 T16484 cc and,IL-4
R14172 T16486 T16484 conj IL-5,IL-4
R14173 T16487 T16488 compound mRNA,expression
R14174 T16488 T16483 dobj expression,inhibits
R14175 T16489 T16488 prep in,expression
R14176 T16490 T16491 amod CD3/CD28-costimulated,cells
R14177 T16491 T16489 pobj cells,in
R14178 T16492 T16479 punct .,RT-PCR
R14179 T16493 T16495 nsubjpass GAPDH,used
R14180 T16494 T16495 auxpass was,used
R14181 T16495 T16495 ROOT used,used
R14182 T16496 T16495 prep as,used
R14183 T16497 T16499 det a,control
R14184 T16498 T16499 compound loading,control
R14185 T16499 T16496 pobj control,as
R14186 T16500 T16495 punct .,used
R14187 T16501 T16502 amod Lower,panels
R14188 T16502 T16503 nsubj panels,show
R14189 T16503 T16503 ROOT show,show
R14190 T16504 T16505 amod graphical,analysis
R14191 T16505 T16503 dobj analysis,show
R14192 T16506 T16505 prep of,analysis
R14193 T16507 T16506 pobj results,of
R14194 T16508 T16507 acl presented,results
R14196 T16510 T16512 amod mean,SEM
R14197 T16511 T16512 compound ±,SEM
R14198 T16512 T16509 pobj SEM,as
R14199 T16513 T16512 prep of,SEM
R14200 T16514 T16515 advmod at,least
R14201 T16515 T16516 advmod least,three
R14202 T16516 T16518 nummod three,experiments
R14203 T16517 T16518 amod independent,experiments
R14204 T16518 T16513 pobj experiments,of
R14205 T16519 T16503 punct .,show
R14206 T16520 T16522 dep ###,<
R14207 T16521 T16522 nmod p,<
R14208 T16522 T16522 ROOT <,<
R14209 T16523 T16532 nsubj 0.001,compared
R14210 T16524 T16532 prep compared,compared
R14211 T16525 T16526 aux to,control
R14212 T16526 T16524 xcomp control,compared
R14213 T16527 T16532 punct ",",compared
R14214 T16528 T16531 nmod ***,0.001
R14215 T16529 T16531 nmod p,0.001
R14216 T16530 T16531 nmod <,0.001
R14217 T16531 T16532 nsubj 0.001,compared
R14218 T16532 T16532 ROOT compared,compared
R14219 T16533 T16532 prep to,compared
R14220 T16534 T16535 compound anti-CD3,/
R14221 T16535 T16536 compound /,CD28
R14222 T16536 T16533 pobj CD28,to
R14223 T16537 T16536 acl stimulated,CD28
R14224 T16538 T16532 punct .,compared
R14225 T16539 T16542 punct (,FP
R14226 T16540 T16542 nmod E,FP
R14227 T16541 T16542 punct ),FP
R14228 T16542 T16547 nsubj FP,reduces
R14229 T16543 T16545 punct (,nM
R14230 T16544 T16545 nummod 10,nM
R14231 T16545 T16542 appos nM,FP
R14232 T16546 T16542 punct ),FP
R14233 T16547 T16547 ROOT reduces,reduces
R14234 T16548 T16549 det the,ability
R14235 T16549 T16547 dobj ability,reduces
R14236 T16550 T16549 prep of,ability
R14237 T16551 T16554 amod anti-CD3,GATA-3
R14238 T16552 T16554 nmod /,GATA-3
R14239 T16553 T16554 amod CD28-stimulated,GATA-3
R14240 T16554 T16550 pobj GATA-3,of
R14241 T16555 T16556 aux to,associate
R14242 T16556 T16549 acl associate,ability
R14243 T16557 T16556 prep with,associate
R14244 T16558 T16561 det the,promoter
R14245 T16559 T16561 amod native,promoter
R14246 T16560 T16561 compound IL-5,promoter
R14247 T16561 T16557 pobj promoter,with
R14248 T16562 T16563 nummod 60,min
R14249 T16563 T16561 appos min,promoter
R14250 T16564 T16563 prep after,min
R14251 T16565 T16564 pobj stimulation,after
R14252 T16566 T16547 punct .,reduces
R14253 T16567 T16570 nsubjpass Data,shown
R14254 T16568 T16570 auxpass are,shown
R14255 T16569 T16570 advmod also,shown
R14256 T16570 T16570 ROOT shown,shown
R14257 T16571 T16570 advmod graphically,shown
R14258 T16572 T16570 prep as,shown
R14259 T16573 T16575 amod mean,SEM
R14260 T16574 T16575 compound ±,SEM
R14261 T16575 T16572 pobj SEM,as
R14262 T16576 T16575 prep of,SEM
R14263 T16577 T16579 nummod three,experiments
R14264 T16578 T16579 amod independent,experiments
R14265 T16579 T16576 pobj experiments,of
R14266 T16580 T16570 punct .,shown
R14267 T16581 T16582 det All,data
R14268 T16582 T16584 nsubjpass data,analysed
R14269 T16583 T16584 auxpass were,analysed
R14270 T16584 T16584 ROOT analysed,analysed
R14271 T16585 T16584 agent by,analysed
R14272 T16586 T16585 pobj ANOVA,by
R14273 T16587 T16584 acl followed,analysed
R14274 T16588 T16587 agent by,followed
R14275 T16589 T16588 pobj Newman-Keuls,by
R14276 T16590 T16590 ROOT post-test,post-test
R14277 T16591 T16584 punct .,analysed
R14886 T17324 T17325 compound p,<
R14887 T17325 T17325 ROOT <,<
R14888 T17326 T17326 ROOT 0.001,0.001
R14889 T17327 T17335 prep compared,compared
R14890 T17328 T17329 aux to,control
R14891 T17329 T17327 xcomp control,compared
R14892 T17330 T17333 punct ",",<
R14893 T17331 T17333 nmod ***,<
R14894 T17332 T17333 nmod p,<
R14895 T17333 T17334 nmod <,0.001
R14896 T17334 T17335 npadvmod 0.001,compared
R14897 T17335 T17326 prep compared,0.001
R14898 T17336 T17335 prep to,compared
R15452 T18004 T18005 compound p,<
R15453 T18005 T18005 ROOT <,<
R15454 T18006 T18015 nsubj 0.001,compared
R15455 T18007 T18015 prep compared,compared
R15456 T18008 T18009 aux to,control
R15457 T18009 T18007 xcomp control,compared
R15458 T18010 T18015 punct ",",compared
R15459 T18011 T18013 nmod ***,<
R15460 T18012 T18013 nmod p,<
R15461 T18013 T18014 nmod <,0.001
R15462 T18014 T18015 nsubj 0.001,compared
R15463 T18015 T18015 ROOT compared,compared
R15464 T18016 T18015 prep to,compared
R16224 T18994 T18995 nmod p,<
R16225 T18995 T18996 nmod <,0.001
R16226 T18996 T18997 nsubj 0.001,compared
R16227 T18997 T18997 ROOT compared,compared
R16228 T18998 T18997 prep to,compared
R7330 T8485 T8482 ccomp affect,investigated
R7331 T8486 T8487 compound anti-CD3,/
R7332 T8487 T8485 dobj /,affect
R7333 T8488 T8487 nummod CD28,/
R7334 T8489 T8482 dep stimulated,investigated
R7335 T8490 T8491 amod nuclear,import
R7336 T8491 T8489 dobj import,stimulated
R7337 T8492 T8491 prep of,import
R7338 T8493 T8492 pobj GATA-3,of
R7339 T8494 T8482 punct .,investigated
R7340 T8495 T8502 nsubj Stimulation,resulted
R7341 T8496 T8495 prep of,Stimulation
R7342 T8497 T8496 pobj cells,of
R7343 T8498 T8497 prep with,cells
R7344 T8499 T8500 compound anti-CD3,/
R7345 T8500 T8498 pobj /,with
R7346 T8501 T8500 nummod CD28,/
R7482 T8637 T8636 prep of,loss
R7483 T8638 T8639 amod GATA-3,binding
R7484 T8639 T8636 amod binding,loss
R7485 T8640 T8639 prep to,binding
R7486 T8641 T8644 det the,promoter
R7488 T8643 T8644 compound IL-5,promoter
R7489 T8644 T8640 pobj promoter,to
R7490 T8645 T8646 punct (,Figure
R7491 T8646 T8644 appos Figure,promoter
R7492 T8647 T8646 nummod 1E,Figure
R7493 T8648 T8646 punct ),Figure
R7494 T8649 T8587 punct .,was
R14195 T16509 T16508 prep as,presented
R16229 T18999 T19002 dep anti-CD3,stimulated
R16230 T19000 T18999 dobj /,anti-CD3
R16231 T19001 T19000 nummod CD28,/
R16232 T19002 T18998 pcomp stimulated,to

GO-BP

Id Subject Object Predicate Lexical cue
T8657 142-157 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T8658 267-281 http://purl.obolibrary.org/obo/GO_0051170 denotes nuclear import
T8659 679-688 http://purl.obolibrary.org/obo/GO_0051235 denotes retention
T16601 1198-1213 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T16602 1234-1248 http://purl.obolibrary.org/obo/GO_0051170 denotes nuclear import
T16603 1594-1606 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T16604 1813-1817 http://purl.obolibrary.org/obo/GO_0004708 denotes MEK1
T16605 2040-2042 http://purl.obolibrary.org/obo/GO_0003964 denotes RT

GO-MF

Id Subject Object Predicate Lexical cue
T8660 66-70 http://purl.obolibrary.org/obo/GO_0005136 denotes IL-4
T8661 137-141 http://purl.obolibrary.org/obo/GO_0005136 denotes IL-4
T8662 991-995 http://purl.obolibrary.org/obo/GO_0005136 denotes IL-4
T8663 1000-1004 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T8664 1076-1080 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T8665 1054-1061 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T16606 1813-1817 http://purl.obolibrary.org/obo/GO_0004708 denotes MEK1
T16607 2040-2042 http://purl.obolibrary.org/obo/GO_0003964 denotes RT
T16608 2072-2076 http://purl.obolibrary.org/obo/GO_0005136 denotes IL-4
T16609 2081-2085 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T16610 2465-2469 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5

GO-CC

Id Subject Object Predicate Lexical cue
T8666 308-313 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16614 1338-1347 http://purl.obolibrary.org/obo/GO_0005737 denotes cytoplasm
T16615 1355-1362 http://purl.obolibrary.org/obo/GO_0005634 denotes nucleus
T16611 1288-1293 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16612 1558-1563 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16613 2127-2132 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T8238 0-75 Sentence denotes The Effect of Corticosteroids on GATA-3 Nuclear Translocation and IL-4 mRNA
T8239 76-184 Sentence denotes Corticosteroids are effective in inhibiting GATA-3-regulated IL-4 gene expression in vitro and in vivo [32].
T8240 185-292 Sentence denotes We therefore investigated whether corticosteroids affect anti-CD3/CD28–stimulated nuclear import of GATA-3.
T8241 293-444 Sentence denotes Stimulation of cells with anti-CD3/CD28 resulted in a rapid cytoplasmic/nuclear GATA-3 translocation (Figure 1A), confirming our previous results [12].
T8242 445-574 Sentence denotes We also confirmed a clear separation of nuclear and cytosolic fractions as indicated by histone H1 and MEK-1 markers (Figure 1B).
T8243 575-786 Sentence denotes The potent topical corticosteroid FP caused sustained loss of nuclear GATA-3 expression and cytoplasmic retention of GATA-3 at concentrations ranging from 10−12 to 10−8 M, which cover the therapeutic range [37].
T8244 787-1102 Sentence denotes This effect was concentration- and time-dependent, with a peak effect of 11.6-fold at 30 min at a concentration of 10−8 M (Figure 1C) and was associated with marked reductions in anti-CD3/CD28–stimulated IL-4 and IL-5 mRNA expression (Figure 1D) and a loss of GATA-3 binding to the native IL-5 promoter (Figure 1E).
T16029 1147-1249 Sentence denotes Fluticasone propionate down-regulates Th2 cytokine gene expression and inhibits GATA-3 nuclear import.
T16030 1250-1749 Sentence denotes (A) Anti-CD3/CD28 treatment of HuT-78 cells results in translocation of GATA-3 from the cytoplasm to the nucleus within 30 min. (B) Histone H1 and MEK-1 were used to confirm distinct separation of cytoplasmic and nuclear extracts in three separate experiments. (C) Western blot analysis of FP-treated HuT-78 cells demonstrated impaired nuclear localization of GATA-3 induced by anti-CD3/CD28 co-stimulation in a time- (at 10−8 M FP) and concentration- (at 60 min after stimulation) dependent manner.
T16031 1750-1812 Sentence denotes Cells were pretreated with FP for 30 min prior to stimulation.
T16032 1813-1909 Sentence denotes MEK1 and histone H1 were used to demonstrate equal cytoplasmic and nuclear loading respectively.
T16033 1910-2133 Sentence denotes Results are presented graphically below as mean±SEM of at least three independent experiments. *** p<0.001 compared to t = 0. (D) RT-PCR showing that FP inhibits IL-4 and IL-5 mRNA expression in CD3/CD28-costimulated cells.
T16034 2134-2170 Sentence denotes GAPDH was used as a loading control.
T16035 2171-2504 Sentence denotes Lower panels show graphical analysis of results presented as mean±SEM of at least three independent experiments. ### p<0.001 compared to control, ***p<0.001 compared to anti-CD3/CD28–stimulated. (E) FP (10 nM) reduces the ability of anti-CD3/CD28-stimulated GATA-3 to associate with the native IL-5 promoter 60 min after stimulation.
T16036 2505-2582 Sentence denotes Data are also shown graphically as mean±SEM of three independent experiments.
T16037 2583-2650 Sentence denotes All data were analysed by ANOVA followed by Newman-Keuls post-test.
T167 0-75 Sentence denotes The Effect of Corticosteroids on GATA-3 Nuclear Translocation and IL-4 mRNA
T168 76-184 Sentence denotes Corticosteroids are effective in inhibiting GATA-3-regulated IL-4 gene expression in vitro and in vivo [32].
T169 185-292 Sentence denotes We therefore investigated whether corticosteroids affect anti-CD3/CD28–stimulated nuclear import of GATA-3.
T170 293-444 Sentence denotes Stimulation of cells with anti-CD3/CD28 resulted in a rapid cytoplasmic/nuclear GATA-3 translocation (Figure 1A), confirming our previous results [12].
T171 445-574 Sentence denotes We also confirmed a clear separation of nuclear and cytosolic fractions as indicated by histone H1 and MEK-1 markers (Figure 1B).
T172 575-786 Sentence denotes The potent topical corticosteroid FP caused sustained loss of nuclear GATA-3 expression and cytoplasmic retention of GATA-3 at concentrations ranging from 10−12 to 10−8 M, which cover the therapeutic range [37].
T173 787-1102 Sentence denotes This effect was concentration- and time-dependent, with a peak effect of 11.6-fold at 30 min at a concentration of 10−8 M (Figure 1C) and was associated with marked reductions in anti-CD3/CD28–stimulated IL-4 and IL-5 mRNA expression (Figure 1D) and a loss of GATA-3 binding to the native IL-5 promoter (Figure 1E).
T174 1103-1249 Sentence denotes 10.1371/journal.pmed.1000076.g001 Figure 1 Fluticasone propionate down-regulates Th2 cytokine gene expression and inhibits GATA-3 nuclear import.
T175 1250-1749 Sentence denotes (A) Anti-CD3/CD28 treatment of HuT-78 cells results in translocation of GATA-3 from the cytoplasm to the nucleus within 30 min. (B) Histone H1 and MEK-1 were used to confirm distinct separation of cytoplasmic and nuclear extracts in three separate experiments. (C) Western blot analysis of FP-treated HuT-78 cells demonstrated impaired nuclear localization of GATA-3 induced by anti-CD3/CD28 co-stimulation in a time- (at 10−8 M FP) and concentration- (at 60 min after stimulation) dependent manner.
T176 1750-1812 Sentence denotes Cells were pretreated with FP for 30 min prior to stimulation.
T177 1813-1909 Sentence denotes MEK1 and histone H1 were used to demonstrate equal cytoplasmic and nuclear loading respectively.
T178 1910-2133 Sentence denotes Results are presented graphically below as mean±SEM of at least three independent experiments. *** p<0.001 compared to t = 0. (D) RT-PCR showing that FP inhibits IL-4 and IL-5 mRNA expression in CD3/CD28-costimulated cells.
T179 2134-2170 Sentence denotes GAPDH was used as a loading control.
T180 2171-2504 Sentence denotes Lower panels show graphical analysis of results presented as mean±SEM of at least three independent experiments. ### p<0.001 compared to control, ***p<0.001 compared to anti-CD3/CD28–stimulated. (E) FP (10 nM) reduces the ability of anti-CD3/CD28-stimulated GATA-3 to associate with the native IL-5 promoter 60 min after stimulation.
T181 2505-2582 Sentence denotes Data are also shown graphically as mean±SEM of three independent experiments.
T182 2583-2650 Sentence denotes All data were analysed by ANOVA followed by Newman-Keuls post-test.

events-check-again

Id Subject Object Predicate Lexical cue Speculation
T8795 4-10 Regulation denotes Effect
T8796 4-10 Regulation denotes Effect
T8797 33-39 Protein denotes GATA-3
T8798 40-47 Entity denotes Nuclear
T8799 48-61 Localization denotes Translocation
T8800 66-70 Protein denotes IL-4
T8801 96-105 Regulation denotes effective
T8802 109-119 Negative_regulation denotes inhibiting
T8803 120-126 Protein denotes GATA-3
T8804 127-136 Regulation denotes regulated
T8805 137-141 Protein denotes IL-4
T8806 147-157 Gene_expression denotes expression
T8807 235-241 Regulation denotes affect true
T8808 256-266 Positive_regulation denotes stimulated
T8809 267-274 Entity denotes nuclear
T8810 275-281 Localization denotes import
T8811 285-291 Protein denotes GATA-3
T8812 333-341 Positive_regulation denotes resulted
T8813 365-372 Entity denotes nuclear
T8814 373-379 Protein denotes GATA-3
T8815 380-393 Localization denotes translocation
T8816 548-553 Protein denotes MEK-1
T8817 612-618 Positive_regulation denotes caused
T8818 612-618 Positive_regulation denotes caused
T8819 629-633 Negative_regulation denotes loss
T8820 637-644 Entity denotes nuclear
T8821 645-651 Protein denotes GATA-3
T8822 652-662 Localization denotes expression
T8823 667-678 Entity denotes cytoplasmic
T8824 679-688 Localization denotes retention
T8825 692-698 Protein denotes GATA-3
T8826 787-798 Regulation denotes This effect
T8827 787-798 Regulation denotes This effect
T8828 787-798 Regulation denotes This effect
T8829 827-836 Regulation denotes dependent
T8830 827-836 Regulation denotes dependent
T8831 827-836 Regulation denotes dependent
T8832 929-939 Regulation denotes associated
T8833 929-939 Regulation denotes associated
T8834 929-939 Regulation denotes associated
T8835 952-962 Negative_regulation denotes reductions
T8836 952-962 Negative_regulation denotes reductions
T8837 980-990 Positive_regulation denotes stimulated
T8838 980-990 Positive_regulation denotes stimulated
T8839 991-995 Protein denotes IL-4
T8840 1000-1004 Protein denotes IL-5
T8841 1005-1020 Transcription denotes mRNA expression
T8842 1005-1020 Transcription denotes mRNA expression
T8843 1039-1043 Negative_regulation denotes loss
T8844 1047-1053 Protein denotes GATA-3
T8845 1054-1061 Binding denotes binding
T8846 1076-1080 Protein denotes IL-5
T8847 1081-1089 Entity denotes promoter
T16674 1218-1226 Negative_regulation denotes inhibits
T16675 1227-1233 Protein denotes GATA-3
T16676 1234-1241 Entity denotes nuclear
T16677 1242-1248 Localization denotes import
T16678 1305-1318 Localization denotes translocation
T16679 1322-1328 Protein denotes GATA-3
T16680 1355-1362 Entity denotes nucleus
T16681 1397-1402 Protein denotes MEK-1
T16682 1586-1593 Entity denotes nuclear
T16683 1594-1606 Localization denotes localization
T16684 1610-1616 Protein denotes GATA-3
T16685 1617-1624 Positive_regulation denotes induced
T16686 1813-1817 Protein denotes MEK1
T16687 2063-2071 Negative_regulation denotes inhibits
T16688 2063-2071 Negative_regulation denotes inhibits
T16689 2072-2076 Protein denotes IL-4
T16690 2081-2085 Protein denotes IL-5
T16691 2086-2101 Transcription denotes mRNA expression
T16692 2086-2101 Transcription denotes mRNA expression
T16693 2105-2108 Protein denotes CD3
T16694 2109-2113 Protein denotes CD28
T16695 2114-2126 Regulation denotes costimulated
T16696 2114-2126 Regulation denotes costimulated
T16697 2381-2388 Negative_regulation denotes reduces
T16698 2418-2428 Positive_regulation denotes stimulated
T16699 2429-2435 Protein denotes GATA-3
T16700 2439-2448 Binding denotes associate
T16701 2465-2469 Protein denotes IL-5
T16702 2470-2478 Entity denotes promoter
R7591 T8797 T8799 themeOf GATA-3,Translocation
R7592 T8798 T8799 locationOf Nuclear,Translocation
R7593 T8799 T8795 themeOf Translocation,Effect
R7594 T8800 T8796 themeOf IL-4,Effect
R7595 T8802 T8801 themeOf inhibiting,effective
R7596 T8803 T8804 causeOf GATA-3,regulated
R7597 T8804 T8802 themeOf regulated,inhibiting
R7598 T8805 T8806 themeOf IL-4,expression
R7599 T8806 T8804 themeOf expression,regulated
R7600 T8808 T8807 themeOf stimulated,affect
R7601 T8809 T8810 locationOf nuclear,import
R7602 T8810 T8808 themeOf import,stimulated
R7603 T8811 T8810 themeOf GATA-3,import
R7604 T8813 T8815 locationOf nuclear,translocation
R7605 T8814 T8815 themeOf GATA-3,translocation
R7606 T8815 T8812 themeOf translocation,resulted
R7607 T8819 T8818 themeOf loss,caused
R7608 T8820 T8822 locationOf nuclear,expression
R7609 T8821 T8822 themeOf GATA-3,expression
R7610 T8822 T8819 themeOf expression,loss
R7611 T8823 T8824 locationOf cytoplasmic,retention
R7612 T8824 T8817 themeOf retention,caused
R7613 T8825 T8824 themeOf GATA-3,retention
R7614 T8826 T8831 themeOf This effect,dependent
R7615 T8827 T8830 themeOf This effect,dependent
R7616 T8828 T8829 themeOf This effect,dependent
R7617 T8832 T8827 themeOf associated,This effect
R7618 T8833 T8828 themeOf associated,This effect
R7619 T8834 T8826 themeOf associated,This effect
R7620 T8835 T8834 themeOf reductions,associated
R7621 T8836 T8832 themeOf reductions,associated
R7622 T8837 T8835 themeOf stimulated,reductions
R7623 T8838 T8836 themeOf stimulated,reductions
R7624 T8839 T8842 themeOf IL-4,mRNA expression
R7625 T8840 T8841 themeOf IL-5,mRNA expression
R7626 T8841 T8838 themeOf mRNA expression,stimulated
R7627 T8842 T8837 themeOf mRNA expression,stimulated
R7628 T8843 T8833 themeOf loss,associated
R7629 T8844 T8845 themeOf GATA-3,binding
R7630 T8845 T8843 themeOf binding,loss
R7631 T8847 T8845 themeOf promoter,binding
R7632 T8847 T8846 partOf promoter,IL-5
R14316 T16675 T16677 themeOf GATA-3,import
R14317 T16676 T16677 locationOf nuclear,import
R14318 T16677 T16674 themeOf import,inhibits
R14319 T16679 T16678 themeOf GATA-3,translocation
R14320 T16680 T16678 locationOf nucleus,translocation
R14321 T16682 T16683 locationOf nuclear,localization
R14322 T16683 T16685 themeOf localization,induced
R14323 T16684 T16683 themeOf GATA-3,localization
R14324 T16689 T16691 themeOf IL-4,mRNA expression
R14325 T16690 T16692 themeOf IL-5,mRNA expression
R14326 T16691 T16688 themeOf mRNA expression,inhibits
R14327 T16692 T16687 themeOf mRNA expression,inhibits
R14328 T16693 T16696 themeOf CD3,costimulated
R14329 T16694 T16695 themeOf CD28,costimulated
R14330 T16699 T16700 themeOf GATA-3,associate
R14331 T16699 T16698 themeOf GATA-3,stimulated
R14332 T16700 T16697 themeOf associate,reduces
R14333 T16702 T16700 themeOf promoter,associate
R14334 T16702 T16701 partOf promoter,IL-5

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T8773 33-61 Protein denotes GATA-3 Nuclear Translocation
T8774 66-75 Protein denotes IL-4 mRNA
T8775 4-10 Regulation denotes Effect
T8776 4-10 Regulation denotes Effect
T8777 120-146 Protein denotes GATA-3-regulated IL-4 gene
T8778 147-157 Gene_expression denotes expression
T8779 109-119 Negative_regulation denotes inhibiting
T8780 242-250 Protein denotes anti-CD3
T8781 251-255 Protein denotes CD28
T8782 285-291 Protein denotes GATA-3
T8783 267-274 Entity denotes nuclear
T8784 275-281 Localization denotes import
T8785 275-281 Localization denotes import
T8786 235-241 Regulation denotes affect
T8787 235-241 Regulation denotes affect
T8788 324-327 Protein denotes CD3
T8789 328-332 Protein denotes CD28
T8790 533-543 Protein denotes histone H1
T8791 548-553 Protein denotes MEK-1
T8792 692-698 Protein denotes GATA-3
T8793 679-688 Localization denotes retention
T8794 629-633 Negative_regulation denotes loss
T8848 971-974 Protein denotes CD3
T8849 975-979 Protein denotes CD28
T8850 991-995 Protein denotes IL-4
T8851 1000-1009 Protein denotes IL-5 mRNA
T8852 1047-1053 Protein denotes GATA-3
T8853 1076-1089 Protein denotes IL-5 promoter
T8854 1010-1020 Gene_expression denotes expression
T8855 1010-1020 Gene_expression denotes expression
T8856 1039-1043 Negative_regulation denotes loss
T8857 1054-1061 Binding denotes binding
T8858 1054-1061 Binding denotes binding
T8859 952-962 Negative_regulation denotes reductions
T8860 952-962 Negative_regulation denotes reductions
T8861 980-990 Positive_regulation denotes stimulated
T8862 980-990 Positive_regulation denotes stimulated
T8863 1039-1043 Negative_regulation denotes loss
T8864 1039-1043 Negative_regulation denotes loss
T16703 1259-1262 Protein denotes CD3
T16704 1263-1267 Protein denotes CD28
T16705 1322-1328 Protein denotes GATA-3
T16706 1355-1362 Entity denotes nucleus
T16707 1305-1318 Localization denotes translocation
T16708 1382-1392 Protein denotes Histone H1
T16709 1397-1402 Protein denotes MEK-1
T16710 1610-1616 Protein denotes GATA-3
T16711 1628-1636 Protein denotes anti-CD3
T16712 1637-1641 Protein denotes CD28
T16713 1586-1593 Entity denotes nuclear
T16714 1594-1606 Localization denotes localization
T16715 1617-1624 Positive_regulation denotes induced
T16716 1577-1585 Negative_regulation denotes impaired
T16717 1813-1817 Protein denotes MEK1
T16718 1822-1832 Protein denotes histone H1
T16719 2060-2062 Protein denotes FP
T16720 2072-2076 Protein denotes IL-4
T16721 2081-2090 Protein denotes IL-5 mRNA
T16722 2105-2108 Protein denotes CD3
T16723 2109-2113 Protein denotes CD28
T16724 2091-2101 Gene_expression denotes expression
T16725 2091-2101 Gene_expression denotes expression
T16726 2063-2071 Negative_regulation denotes inhibits
T16727 2063-2071 Negative_regulation denotes inhibits
T16728 2134-2139 Protein denotes GAPDH
T16729 2345-2348 Protein denotes CD3
T16730 2349-2353 Protein denotes CD28
T16731 2409-2412 Protein denotes CD3
T16732 2413-2417 Protein denotes CD28
T16733 2429-2435 Protein denotes GATA-3
T16734 2465-2485 Protein denotes IL-5 promoter 60 min
T16735 2418-2428 Positive_regulation denotes stimulated
T16736 2439-2448 Binding denotes associate
T16737 2381-2388 Negative_regulation denotes reduces
T16738 2609-2614 Protein denotes ANOVA
T19211 2345-2348 Protein denotes CD3
T19212 2349-2353 Protein denotes CD28
R7579 T8773 T8775 themeOf GATA-3 Nuclear Translocation,Effect
R7580 T8774 T8776 themeOf IL-4 mRNA,Effect
R7581 T8777 T8778 themeOf GATA-3-regulated IL-4 gene,expression
R7582 T8778 T8779 themeOf expression,inhibiting
R7583 T8780 T8784 themeOf anti-CD3,import
R7584 T8782 T8785 themeOf GATA-3,import
R7585 T8783 T8784 locationOf nuclear,import
R7586 T8783 T8785 locationOf nuclear,import
R7587 T8784 T8786 themeOf import,affect
R7588 T8785 T8787 themeOf import,affect
R7589 T8792 T8793 themeOf GATA-3,retention
R7590 T8793 T8794 themeOf retention,loss
R7633 T8849 T8861 causeOf CD28,stimulated
R7634 T8849 T8862 causeOf CD28,stimulated
R7635 T8850 T8854 themeOf IL-4,expression
R7636 T8851 T8855 themeOf IL-5 mRNA,expression
R7637 T8852 T8856 themeOf GATA-3,loss
R7638 T8852 T8857 themeOf GATA-3,binding
R7639 T8852 T8858 themeOf GATA-3,binding
R7640 T8853 T8858 themeOf IL-5 promoter,binding
R7641 T8854 T8859 themeOf expression,reductions
R7642 T8854 T8861 themeOf expression,stimulated
R7643 T8855 T8860 themeOf expression,reductions
R7644 T8855 T8862 themeOf expression,stimulated
R7645 T8857 T8863 themeOf binding,loss
R7646 T8858 T8864 themeOf binding,loss
R14335 T16705 T16707 themeOf GATA-3,translocation
R14336 T16706 T16707 locationOf nucleus,translocation
R14337 T16710 T16714 themeOf GATA-3,localization
R14338 T16713 T16714 locationOf nuclear,localization
R14339 T16714 T16715 themeOf localization,induced
R14340 T16714 T16716 themeOf localization,impaired
R14341 T16719 T16726 causeOf FP,inhibits
R14342 T16719 T16727 causeOf FP,inhibits
R14343 T16720 T16724 themeOf IL-4,expression
R14344 T16721 T16725 themeOf IL-5 mRNA,expression
R14345 T16724 T16726 themeOf expression,inhibits
R14346 T16725 T16727 themeOf expression,inhibits
R14347 T16732 T16735 causeOf CD28,stimulated
R14348 T16733 T16735 themeOf GATA-3,stimulated
R14349 T16733 T16736 themeOf GATA-3,associate
R14350 T16734 T16736 themeOf IL-5 promoter 60 min,associate
R14351 T16735 T16737 themeOf stimulated,reduces

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Speculation
T8186 4-10 Regulation denotes Effect
T8187 33-39 Protein denotes GATA-3
T8188 40-47 Entity denotes Nuclear
T8189 48-61 Localization denotes Translocation
T8190 66-70 Protein denotes IL-4
T8191 96-105 Regulation denotes effective
T8192 109-119 Negative_regulation denotes inhibiting
T8193 120-126 Protein denotes GATA-3
T8194 127-136 Regulation denotes regulated
T8195 137-141 Protein denotes IL-4
T8196 147-157 Gene_expression denotes expression
T8197 235-241 Regulation denotes affect true
T8198 256-266 Positive_regulation denotes stimulated
T8199 267-274 Entity denotes nuclear
T8200 275-281 Localization denotes import
T8201 285-291 Protein denotes GATA-3
T8202 333-341 Positive_regulation denotes resulted
T8203 365-372 Entity denotes nuclear
T8204 373-379 Protein denotes GATA-3
T8205 380-393 Localization denotes translocation
T8206 548-553 Protein denotes MEK-1
T8207 612-618 Positive_regulation denotes caused
T8208 612-618 Positive_regulation denotes caused
T8209 629-633 Negative_regulation denotes loss
T8210 637-644 Entity denotes nuclear
T8211 645-651 Protein denotes GATA-3
T8212 652-662 Localization denotes expression
T8213 667-678 Entity denotes cytoplasmic
T8214 679-688 Localization denotes retention
T8215 692-698 Protein denotes GATA-3
T8216 787-798 Regulation denotes This effect
T8217 787-798 Regulation denotes This effect
T8218 787-798 Regulation denotes This effect
T8219 827-836 Regulation denotes dependent
T8220 827-836 Regulation denotes dependent
T8221 827-836 Regulation denotes dependent
T8222 929-939 Regulation denotes associated
T8223 929-939 Regulation denotes associated
T8224 929-939 Regulation denotes associated
T8225 952-962 Negative_regulation denotes reductions
T8226 952-962 Negative_regulation denotes reductions
T8227 980-990 Positive_regulation denotes stimulated
T8228 980-990 Positive_regulation denotes stimulated
T8229 991-995 Protein denotes IL-4
T8230 1000-1004 Protein denotes IL-5
T8231 1005-1020 Transcription denotes mRNA expression
T8232 1005-1020 Transcription denotes mRNA expression
T8233 1039-1043 Negative_regulation denotes loss
T8234 1047-1053 Protein denotes GATA-3
T8235 1054-1061 Binding denotes binding
T8236 1076-1080 Protein denotes IL-5
T8237 1081-1089 Entity denotes promoter
T16000 1218-1226 Negative_regulation denotes inhibits
T16001 1227-1233 Protein denotes GATA-3
T16002 1234-1241 Entity denotes nuclear
T16003 1242-1248 Localization denotes import
T16004 1305-1318 Localization denotes translocation
T16005 1322-1328 Protein denotes GATA-3
T16006 1355-1362 Entity denotes nucleus
T16007 1397-1402 Protein denotes MEK-1
T16008 1586-1593 Entity denotes nuclear
T16009 1594-1606 Localization denotes localization
T16010 1610-1616 Protein denotes GATA-3
T16011 1617-1624 Positive_regulation denotes induced
T16012 1813-1817 Protein denotes MEK1
T16013 2063-2071 Negative_regulation denotes inhibits
T16014 2063-2071 Negative_regulation denotes inhibits
T16015 2072-2076 Protein denotes IL-4
T16016 2081-2085 Protein denotes IL-5
T16017 2086-2101 Transcription denotes mRNA expression
T16018 2086-2101 Transcription denotes mRNA expression
T16019 2105-2108 Protein denotes CD3
T16020 2109-2113 Protein denotes CD28
T16021 2114-2126 Regulation denotes costimulated
T16022 2114-2126 Regulation denotes costimulated
T16023 2381-2388 Negative_regulation denotes reduces
T16024 2418-2428 Positive_regulation denotes stimulated
T16025 2429-2435 Protein denotes GATA-3
T16026 2439-2448 Binding denotes associate
T16027 2465-2469 Protein denotes IL-5
T16028 2470-2478 Entity denotes promoter
T8185 4-10 Regulation denotes Effect
R7090 T8205 T8202 themeOf translocation,resulted
R7091 T8209 T8208 themeOf loss,caused
R7092 T8210 T8212 locationOf nuclear,expression
R7093 T8211 T8212 themeOf GATA-3,expression
R7094 T8212 T8209 themeOf expression,loss
R7095 T8213 T8214 locationOf cytoplasmic,retention
R7096 T8214 T8207 themeOf retention,caused
R7097 T8215 T8214 themeOf GATA-3,retention
R7098 T8216 T8221 themeOf This effect,dependent
R7099 T8217 T8220 themeOf This effect,dependent
R7100 T8218 T8219 themeOf This effect,dependent
R7101 T8222 T8217 themeOf associated,This effect
R7102 T8223 T8218 themeOf associated,This effect
R7103 T8224 T8216 themeOf associated,This effect
R7104 T8225 T8224 themeOf reductions,associated
R7105 T8226 T8222 themeOf reductions,associated
R7106 T8227 T8225 themeOf stimulated,reductions
R7107 T8228 T8226 themeOf stimulated,reductions
R7108 T8229 T8232 themeOf IL-4,mRNA expression
R7109 T8230 T8231 themeOf IL-5,mRNA expression
R7110 T8231 T8228 themeOf mRNA expression,stimulated
R7111 T8232 T8227 themeOf mRNA expression,stimulated
R7112 T8233 T8223 themeOf loss,associated
R7113 T8234 T8235 themeOf GATA-3,binding
R7114 T8235 T8233 themeOf binding,loss
R7115 T8237 T8235 themeOf promoter,binding
R7116 T8237 T8236 partOf promoter,IL-5
R13739 T16003 T16000 themeOf import,inhibits
R13737 T16001 T16003 themeOf GATA-3,import
R13738 T16002 T16003 locationOf nuclear,import
R13740 T16005 T16004 themeOf GATA-3,translocation
R13741 T16006 T16004 locationOf nucleus,translocation
R13742 T16008 T16009 locationOf nuclear,localization
R13743 T16009 T16011 themeOf localization,induced
R13744 T16010 T16009 themeOf GATA-3,localization
R13745 T16015 T16017 themeOf IL-4,mRNA expression
R13746 T16016 T16018 themeOf IL-5,mRNA expression
R13747 T16017 T16014 themeOf mRNA expression,inhibits
R13748 T16018 T16013 themeOf mRNA expression,inhibits
R13749 T16019 T16022 themeOf CD3,costimulated
R13750 T16020 T16021 themeOf CD28,costimulated
R13751 T16025 T16026 themeOf GATA-3,associate
R13752 T16025 T16024 themeOf GATA-3,stimulated
R13753 T16026 T16023 themeOf associate,reduces
R13754 T16028 T16026 themeOf promoter,associate
R13755 T16028 T16027 partOf promoter,IL-5
R7075 T8187 T8189 themeOf GATA-3,Translocation
R7076 T8188 T8189 locationOf Nuclear,Translocation
R7077 T8189 T8185 themeOf Translocation,Effect
R7078 T8190 T8186 themeOf IL-4,Effect
R7079 T8192 T8191 themeOf inhibiting,effective
R7080 T8193 T8194 causeOf GATA-3,regulated
R7081 T8194 T8192 themeOf regulated,inhibiting
R7082 T8195 T8196 themeOf IL-4,expression
R7083 T8196 T8194 themeOf expression,regulated
R7084 T8198 T8197 themeOf stimulated,affect
R7085 T8199 T8200 locationOf nuclear,import
R7086 T8200 T8198 themeOf import,stimulated
R7087 T8201 T8200 themeOf GATA-3,import
R7088 T8203 T8205 locationOf nuclear,translocation
R7089 T8204 T8205 themeOf GATA-3,translocation

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T8423 33-39 P23771 denotes GATA-3
T8424 66-70 P05112 denotes IL-4
T8425 120-126 P23771 denotes GATA-3
T8426 137-141 P05112 denotes IL-4
T8427 247-250 P04234 denotes CD3
T8428 247-250 P20963 denotes CD3
T8429 247-250 P07766 denotes CD3
T8430 247-250 P09693 denotes CD3
T8431 251-255 P10747 denotes CD28
T8432 285-291 P23771 denotes GATA-3
T8433 324-327 P04234 denotes CD3
T8434 324-327 P20963 denotes CD3
T8435 324-327 P07766 denotes CD3
T8436 324-327 P09693 denotes CD3
T8437 328-332 P10747 denotes CD28
T8438 373-379 P23771 denotes GATA-3
T8439 548-553 Q02750 denotes MEK-1
T8440 645-651 P23771 denotes GATA-3
T8441 692-698 P23771 denotes GATA-3
T8442 971-974 P20963 denotes CD3
T8443 971-974 P09693 denotes CD3
T8444 971-974 P07766 denotes CD3
T8445 971-974 P04234 denotes CD3
T8446 975-979 P10747 denotes CD28
T8447 991-995 P05112 denotes IL-4
T8448 1000-1004 P05113 denotes IL-5
T8449 1047-1053 P23771 denotes GATA-3
T8450 1076-1080 P05113 denotes IL-5
T16280 1227-1233 P23771 denotes GATA-3
T16281 1259-1262 P09693 denotes CD3
T16282 1259-1262 P20963 denotes CD3
T16283 1259-1262 P04234 denotes CD3
T16284 1259-1262 P07766 denotes CD3
T16285 1263-1267 P10747 denotes CD28
T16286 1322-1328 P23771 denotes GATA-3
T16287 1397-1402 Q02750 denotes MEK-1
T16288 1610-1616 P23771 denotes GATA-3
T16289 1633-1636 P04234 denotes CD3
T16290 1633-1636 P20963 denotes CD3
T16291 1633-1636 P07766 denotes CD3
T16292 1633-1636 P09693 denotes CD3
T16293 1637-1641 P10747 denotes CD28
T16294 1813-1817 Q02750 denotes MEK1
T16295 2072-2076 P05112 denotes IL-4
T16296 2081-2085 P05113 denotes IL-5
T16297 2105-2108 P09693 denotes CD3
T16298 2105-2108 P04234 denotes CD3
T16299 2105-2108 P07766 denotes CD3
T16300 2105-2108 P20963 denotes CD3
T16301 2109-2113 P10747 denotes CD28
T16302 2134-2139 P04406 denotes GAPDH
T16303 2345-2348 P04234 denotes CD3
T16304 2345-2348 P20963 denotes CD3
T16305 2345-2348 P07766 denotes CD3
T16306 2345-2348 P09693 denotes CD3
T16307 2349-2353 P10747 denotes CD28
T16308 2409-2412 P09693 denotes CD3
T16309 2409-2412 P20963 denotes CD3
T16310 2409-2412 P04234 denotes CD3
T16311 2409-2412 P07766 denotes CD3
T16312 2413-2417 P10747 denotes CD28
T16313 2429-2435 P23771 denotes GATA-3
T16314 2465-2469 P05113 denotes IL-5
T18905 2345-2348 P20963 denotes CD3
T18906 2345-2348 P09693 denotes CD3
T18907 2345-2348 P07766 denotes CD3
T18908 2345-2348 P04234 denotes CD3
T18909 2349-2353 P10747 denotes CD28

test2

Id Subject Object Predicate Lexical cue Speculation
T8147 4-10 Regulation denotes Effect
T8148 33-39 Protein denotes GATA-3
T8149 40-47 Entity denotes Nuclear
T8150 48-61 Localization denotes Translocation
T8151 66-70 Protein denotes IL-4
T8152 109-119 Negative_regulation denotes inhibiting
T8153 120-126 Protein denotes GATA-3
T8154 127-136 Regulation denotes regulated true
T8155 137-141 Protein denotes IL-4
T8156 147-157 Gene_expression denotes expression
T8157 235-241 Regulation denotes affect
T8158 256-266 Positive_regulation denotes stimulated
T8159 267-274 Entity denotes nuclear
T8160 275-281 Localization denotes import
T8161 285-291 Protein denotes GATA-3
T8162 333-341 Positive_regulation denotes resulted
T8163 365-372 Entity denotes nuclear
T8164 373-379 Protein denotes GATA-3
T8165 380-393 Localization denotes translocation
T8166 548-553 Protein denotes MEK-1
T8167 619-628 Positive_regulation denotes sustained
T8168 629-633 Negative_regulation denotes loss
T8169 637-644 Entity denotes nuclear
T8170 645-651 Protein denotes GATA-3
T8171 652-662 Gene_expression denotes expression
T8172 667-678 Entity denotes cytoplasmic
T8173 679-688 Localization denotes retention
T8174 692-698 Protein denotes GATA-3
T8175 952-962 Negative_regulation denotes reductions
T8176 980-990 Positive_regulation denotes stimulated
T8177 991-995 Protein denotes IL-4
T8178 1000-1004 Protein denotes IL-5
T8179 1005-1020 Transcription denotes mRNA expression
T8180 1039-1043 Negative_regulation denotes loss
T8181 1047-1053 Protein denotes GATA-3
T8182 1054-1061 Binding denotes binding
T8183 1076-1080 Protein denotes IL-5
T8184 1081-1089 Entity denotes promoter
T15975 1218-1226 Negative_regulation denotes inhibits
T15976 1227-1233 Protein denotes GATA-3
T15977 1234-1241 Entity denotes nuclear
T15978 1242-1248 Localization denotes import
T15979 1305-1318 Localization denotes translocation
T15980 1322-1328 Protein denotes GATA-3
T15981 1355-1362 Entity denotes nucleus
T15982 1397-1402 Protein denotes MEK-1
T15983 1577-1585 Negative_regulation denotes impaired
T15984 1586-1593 Entity denotes nuclear
T15985 1594-1606 Localization denotes localization
T15986 1610-1616 Protein denotes GATA-3
T15987 1617-1624 Positive_regulation denotes induced
T15988 1813-1817 Protein denotes MEK1
T15989 2063-2071 Negative_regulation denotes inhibits
T15990 2072-2076 Protein denotes IL-4
T15991 2081-2085 Protein denotes IL-5
T15992 2086-2101 Transcription denotes mRNA expression
T15993 2105-2108 Protein denotes CD3
T15994 2109-2113 Protein denotes CD28
T15995 2381-2388 Negative_regulation denotes reduces
T15996 2418-2428 Positive_regulation denotes stimulated
T15997 2429-2435 Protein denotes GATA-3
T15998 2439-2448 Binding denotes associate
T15999 2465-2469 Protein denotes IL-5
R7047 T8148 T8150 themeOf GATA-3,Translocation
R7048 T8149 T8150 locationOf Nuclear,Translocation
R7049 T8150 T8147 themeOf Translocation,Effect
R7050 T8151 T8147 themeOf IL-4,Effect
R7051 T8153 T8154 causeOf GATA-3,regulated
R7052 T8154 T8152 themeOf regulated,inhibiting
R7053 T8155 T8156 themeOf IL-4,expression
R7054 T8156 T8154 themeOf expression,regulated
R7055 T8159 T8160 locationOf nuclear,import
R7056 T8160 T8158 themeOf import,stimulated
R7057 T8161 T8160 themeOf GATA-3,import
R7058 T8163 T8165 locationOf nuclear,translocation
R7059 T8164 T8165 themeOf GATA-3,translocation
R7060 T8165 T8162 themeOf translocation,resulted
R7061 T8168 T8167 themeOf loss,sustained
R7062 T8169 T8171 locationOf nuclear,expression
R7063 T8170 T8171 themeOf GATA-3,expression
R7064 T8171 T8168 themeOf expression,loss
R7065 T8172 T8173 locationOf cytoplasmic,retention
R7066 T8173 T8168 themeOf retention,loss
R7067 T8174 T8173 themeOf GATA-3,retention
R7068 T8177 T8179 themeOf IL-4,mRNA expression
R7069 T8178 T8179 themeOf IL-5,mRNA expression
R7070 T8179 T8176 themeOf mRNA expression,stimulated
R7071 T8181 T8182 themeOf GATA-3,binding
R7072 T8182 T8180 themeOf binding,loss
R7073 T8184 T8182 themeOf promoter,binding
R7074 T8184 T8183 partOf promoter,IL-5
R13720 T15976 T15978 themeOf GATA-3,import
R13721 T15977 T15978 locationOf nuclear,import
R13722 T15978 T15975 themeOf import,inhibits
R13723 T15980 T15979 themeOf GATA-3,translocation
R13724 T15981 T15979 locationOf nucleus,translocation
R13725 T15984 T15985 locationOf nuclear,localization
R13726 T15985 T15983 themeOf localization,impaired
R13727 T15985 T15987 themeOf localization,induced
R13728 T15986 T15985 themeOf GATA-3,localization
R13729 T15987 T15983 themeOf induced,impaired
R13730 T15990 T15992 themeOf IL-4,mRNA expression
R13731 T15991 T15992 themeOf IL-5,mRNA expression
R13732 T15992 T15989 themeOf mRNA expression,inhibits
R13733 T15996 T15995 themeOf stimulated,reduces
R13734 T15997 T15998 themeOf GATA-3,associate
R13735 T15997 T15996 themeOf GATA-3,stimulated
R13736 T15998 T15995 themeOf associate,reduces