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PMC:2674207 / 2181-3455 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T20 0-10 Sentence denotes Background
T21 11-98 Sentence denotes The immune system protects the human body from viruses, bacteria, parasites, and fungi.
T22 99-374 Sentence denotes When one of these foreign invaders enters the body, immune system cells called T lymphocytes recognize specific molecules on the invader's surface and release chemical messengers (cytokines) that recruit and activate other types of immune cell, which then attack the invader.
T23 375-606 Sentence denotes Sometimes, however, the immune system responds to a normally harmless material (for example, house-dust mites or grass pollen; scientists call these materials allergens) and triggers an allergic disease such as asthma or hay fever.
T24 607-793 Sentence denotes Contact with an allergen activates a type of T lymphocyte called a T helper-2 (Th2) cell that subsequently makes (expresses) three cytokines called interleukin-4 (IL-4), IL-5, and IL-13.
T25 794-899 Sentence denotes These cytokines ultimately cause inflammation (swelling) of the part of the body exposed to the allergen.
T26 900-1032 Sentence denotes Corticosteroids, which suppress the expression of cytokines by Th2 cells, are often used to treat inflammation in allergic diseases.
T27 1033-1274 Sentence denotes Other treatments for these common conditions—about 50 million people in the US have an allergic disease—include minimizing exposure to allergens and diminishing the response of the immune system to allergens by using various immunotherapies.