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PMC:2674207 / 112-956 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T165 1-8 NN denotes Disease
T166 343-353 NN denotes Background
T167 354-360 NN denotes GATA-3
T168 361-366 VB denotes plays
T169 367-368 DT denotes a
T170 369-377 JJ denotes critical
T171 378-382 NN denotes role
T172 383-385 IN denotes in
T173 386-396 VB denotes regulating
T174 397-400 DT denotes the
T175 401-411 NN denotes expression
T176 412-414 IN denotes of
T177 415-418 DT denotes the
T178 419-428 NN denotes cytokines
T179 429-440 NN denotes interleukin
T180 441-442 -LRB- denotes (
T181 442-444 NN denotes IL
T182 444-445 -RRB- denotes )
T183 445-447 CD denotes -4
T184 447-448 -COMMA- denotes ,
T185 449-453 NN denotes IL-5
T186 453-454 -COMMA- denotes ,
T187 455-458 CC denotes and
T188 459-464 NN denotes IL-13
T189 465-469 IN denotes from
T190 470-471 NN denotes T
T191 472-480 NN denotes helper-2
T192 481-482 -LRB- denotes (
T193 482-485 NN denotes Th2
T194 485-486 -RRB- denotes )
T195 487-492 NN denotes cells
T196 493-496 CC denotes and
T197 497-506 RB denotes therefore
T198 507-509 VB denotes is
T199 510-511 DT denotes a
T200 512-515 JJ denotes key
T201 516-524 NN denotes mediator
T202 525-527 IN denotes of
T203 528-536 JJ denotes allergic
T204 537-545 NN denotes diseases
T205 547-562 NN denotes Corticosteroids
T206 563-566 VB denotes are
T207 567-573 RB denotes highly
T208 574-583 JJ denotes effective
T209 584-586 IN denotes in
T210 587-598 VB denotes suppressing
T211 599-607 JJ denotes allergic
T212 608-620 NN denotes inflammation
T213 620-621 -COMMA- denotes ,
T214 622-625 CC denotes but
T215 626-631 PRP-DOLLAR- denotes their
T216 632-639 NN denotes effects
T217 640-642 IN denotes on
T218 643-649 NN denotes GATA-3
T219 650-653 VB denotes are
T220 654-661 JJ denotes unknown
T221 663-665 PRP denotes We
T222 666-678 VB denotes investigated
T223 679-682 DT denotes the
T224 683-689 NN denotes effect
T225 690-692 IN denotes of
T226 693-696 DT denotes the
T227 697-711 NN denotes corticosteroid
T228 712-723 NN denotes fluticasone
T229 724-734 NN denotes propionate
T230 735-737 IN denotes on
T231 738-744 NN denotes GATA-3
T232 745-755 NN denotes regulation
T233 756-758 IN denotes in
T234 759-764 JJ denotes human
T235 765-778 NN denotes T-lymphocytes
T236 779-781 FW denotes in
T237 782-787 FW denotes vitro
T238 788-791 CC denotes and
T239 792-794 FW denotes in
T240 795-799 FW denotes vivo
T241 802-809 NN denotes Methods
T242 810-813 CC denotes and
T243 814-822 NN denotes Findings
T244 823-825 IN denotes In
T245 826-827 DT denotes a
T246 828-829 NN denotes T
T247 830-840 NN denotes lymphocyte
R115 T167 T168 arg1Of GATA-3,plays
R116 T167 T173 arg1Of GATA-3,regulating
R117 T167 T198 arg1Of GATA-3,is
R118 T168 T172 arg1Of plays,in
R119 T168 T196 arg1Of plays,and
R120 T171 T168 arg2Of role,plays
R121 T171 T169 arg1Of role,a
R122 T171 T170 arg1Of role,critical
R123 T173 T172 arg2Of regulating,in
R124 T175 T173 arg2Of expression,regulating
R125 T175 T174 arg1Of expression,the
R126 T175 T176 arg1Of expression,of
R127 T175 T189 arg1Of expression,from
R128 T178 T177 arg1Of cytokines,the
R129 T179 T180 arg1Of interleukin,(
R130 T179 T183 arg1Of interleukin,-4
R131 T179 T184 arg1Of interleukin,","
R132 T181 T180 arg2Of IL,(
R133 T182 T180 arg3Of ),(
R134 T184 T187 arg1Of ",",and
R135 T185 T184 arg2Of IL-5,","
R136 T187 T176 arg2Of and,of
R137 T187 T178 arg1Of and,cytokines
R138 T187 T186 arg1Of and,","
R139 T188 T187 arg2Of IL-13,and
R140 T193 T192 arg2Of Th2,(
R141 T194 T192 arg3Of ),(
R142 T195 T189 arg2Of cells,from
R143 T195 T190 arg1Of cells,T
R144 T195 T191 arg1Of cells,helper-2
R145 T195 T192 arg1Of cells,(
R146 T198 T196 arg2Of is,and
R147 T198 T197 arg1Of is,therefore
R148 T201 T198 arg2Of mediator,is
R149 T201 T199 arg1Of mediator,a
R150 T201 T200 arg1Of mediator,key
R151 T201 T202 arg1Of mediator,of
R152 T204 T202 arg2Of diseases,of
R153 T204 T203 arg1Of diseases,allergic
R154 T205 T206 arg1Of Corticosteroids,are
R155 T205 T208 arg1Of Corticosteroids,effective
R156 T206 T214 arg1Of are,but
R157 T208 T206 arg2Of effective,are
R158 T208 T207 arg1Of effective,highly
R159 T208 T209 arg1Of effective,in
R160 T210 T209 arg2Of suppressing,in
R161 T212 T210 arg2Of inflammation,suppressing
R162 T212 T211 arg1Of inflammation,allergic
R163 T214 T213 arg1Of but,","
R164 T216 T215 arg1Of effects,their
R165 T216 T217 arg1Of effects,on
R166 T216 T219 arg1Of effects,are
R167 T216 T220 arg1Of effects,unknown
R168 T218 T217 arg2Of GATA-3,on
R169 T219 T214 arg2Of are,but
R170 T220 T219 arg2Of unknown,are
R171 T221 T222 arg1Of We,investigated
R172 T222 T237 arg1Of investigated,vitro
R173 T222 T240 arg1Of investigated,vivo
R174 T224 T222 arg2Of effect,investigated
R175 T224 T223 arg1Of effect,the
R176 T224 T225 arg1Of effect,of
R177 T224 T230 arg1Of effect,on
R178 T229 T225 arg2Of propionate,of
R179 T229 T226 arg1Of propionate,the
R180 T229 T227 arg1Of propionate,corticosteroid
R181 T229 T228 arg1Of propionate,fluticasone
R182 T232 T230 arg2Of regulation,on
R183 T232 T231 arg1Of regulation,GATA-3
R184 T232 T233 arg1Of regulation,in
R185 T235 T233 arg2Of T-lymphocytes,in
R186 T235 T234 arg1Of T-lymphocytes,human
R187 T237 T236 arg1Of vitro,in
R188 T237 T238 arg1Of vitro,and
R189 T240 T238 arg2Of vivo,and
R190 T240 T239 arg1Of vivo,in
R191 T241 T242 arg1Of Methods,and
R192 T243 T242 arg2Of Findings,and

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T426 415-428 Anaphor denotes the cytokines
T427 429-447 Antecedent denotes interleukin (IL)-4
T428 449-453 Antecedent denotes IL-5
T429 459-464 Antecedent denotes IL-13
R768 T426 T427 boundBy the cytokines,interleukin (IL)-4
R777 T426 T428 boundBy the cytokines,IL-5
R778 T426 T429 boundBy the cytokines,IL-13

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T477 383-385 IN denotes in
T478 386-396 VBG denotes regulating
T479 397-400 DT denotes the
T480 401-411 NN denotes expression
T481 412-414 IN denotes of
T482 415-418 DT denotes the
T483 419-428 NNS denotes cytokines
T484 429-440 VBP denotes interleukin
T485 441-442 -LRB- denotes (
T486 442-444 NNP denotes IL
T487 444-445 -RRB- denotes )
T488 445-447 CD denotes -4
T489 447-448 , denotes ,
T490 449-453 NN denotes IL-5
T491 453-454 , denotes ,
T492 455-458 CC denotes and
T493 459-464 NN denotes IL-13
T494 465-469 IN denotes from
T495 470-471 NNP denotes T
T496 472-480 JJ denotes helper-2
T497 481-482 -LRB- denotes (
T498 482-485 JJ denotes Th2
T499 485-486 -RRB- denotes )
T500 487-492 NNS denotes cells
T501 493-496 CC denotes and
T502 497-506 RB denotes therefore
T503 507-509 VBZ denotes is
T504 510-511 DT denotes a
T505 512-515 JJ denotes key
T506 516-524 NN denotes mediator
T507 525-527 IN denotes of
T508 528-536 JJ denotes allergic
T509 537-545 NNS denotes diseases
T510 545-546 . denotes .
T511 547-562 NNS denotes Corticosteroids
T512 563-566 VBP denotes are
T513 567-573 RB denotes highly
T514 574-583 JJ denotes effective
T515 584-586 IN denotes in
T516 587-598 VBG denotes suppressing
T517 599-607 JJ denotes allergic
T518 608-620 NN denotes inflammation
T519 620-621 , denotes ,
T520 622-625 CC denotes but
T521 626-631 PRP$ denotes their
T522 632-639 NNS denotes effects
T523 640-642 IN denotes on
T524 643-649 NN denotes GATA-3
T525 650-653 VBP denotes are
T526 654-661 JJ denotes unknown
T527 661-662 . denotes .
T528 663-665 PRP denotes We
T529 666-678 VBD denotes investigated
T530 679-682 DT denotes the
T531 683-689 NN denotes effect
T532 690-692 IN denotes of
T533 693-696 DT denotes the
T534 697-711 JJ denotes corticosteroid
T535 712-723 NN denotes fluticasone
T536 724-734 NN denotes propionate
T537 735-737 IN denotes on
T538 738-744 JJ denotes GATA-3
T539 745-755 NN denotes regulation
T540 756-758 IN denotes in
T541 759-764 JJ denotes human
T542 765-778 NNS denotes T-lymphocytes
T543 779-781 IN denotes in
T544 782-787 NN denotes vitro
T545 788-791 CC denotes and
T546 792-794 IN denotes in
T547 795-799 NN denotes vivo
T548 799-800 . denotes .
T549 802-809 NNS denotes Methods
T550 810-813 CC denotes and
T551 814-822 NNS denotes Findings
T552 823-825 IN denotes In
T553 826-827 DT denotes a
T554 828-829 NNP denotes T
T555 830-840 NN denotes lymphocyte
T470 1-8 NNP denotes Disease
T471 343-353 NNP denotes Background
T472 354-360 NNP denotes GATA-3
T473 361-366 VBZ denotes plays
T474 367-368 DT denotes a
T475 369-377 JJ denotes critical
T476 378-382 NN denotes role
R374 T484 T488 nmod interleukin,-4
R375 T477 T476 prep in,role
R376 T478 T477 pcomp regulating,in
R377 T479 T480 det the,expression
R378 T480 T478 dobj expression,regulating
R379 T485 T484 punct (,interleukin
R380 T481 T480 prep of,expression
R381 T482 T483 det the,cytokines
R382 T483 T481 pobj cytokines,of
R383 T486 T484 appos IL,interleukin
R384 T487 T484 punct ),interleukin
R385 T488 T473 npadvmod -4,plays
R386 T489 T488 punct ",",-4
R387 T490 T488 conj IL-5,-4
R436 T516 T515 pcomp suppressing,in
R444 T517 T518 amod allergic,inflammation
R448 T518 T516 dobj inflammation,suppressing
R452 T519 T512 punct ",",are
R456 T520 T512 cc but,are
R463 T521 T522 poss their,effects
R467 T522 T525 nsubj effects,are
R471 T523 T522 prep on,effects
R474 T524 T523 pobj GATA-3,on
R479 T525 T512 conj are,are
R482 T526 T525 acomp unknown,are
R483 T527 T525 punct .,are
R484 T528 T529 nsubj We,investigated
R485 T529 T529 ROOT investigated,investigated
R487 T530 T531 det the,effect
R488 T531 T529 dobj effect,investigated
R489 T532 T531 prep of,effect
R490 T533 T536 det the,propionate
R491 T534 T536 amod corticosteroid,propionate
R493 T535 T536 compound fluticasone,propionate
R494 T536 T532 pobj propionate,of
R495 T537 T536 prep on,propionate
R496 T538 T539 amod GATA-3,regulation
R497 T539 T537 pobj regulation,on
R498 T540 T539 prep in,regulation
R500 T541 T542 amod human,T-lymphocytes
R501 T542 T540 pobj T-lymphocytes,in
R502 T543 T539 prep in,regulation
R503 T544 T543 pobj vitro,in
R504 T545 T543 cc and,in
R506 T546 T543 conj in,in
R508 T547 T546 pobj vivo,in
R511 T548 T529 punct .,investigated
R512 T549 T549 ROOT Methods,Methods
R514 T550 T549 cc and,Methods
R518 T551 T549 conj Findings,Methods
R795 T470 T472 compound Disease,GATA-3
R796 T471 T472 compound Background,GATA-3
R797 T472 T473 nsubj GATA-3,plays
R798 T473 T473 ROOT plays,plays
R799 T474 T476 det a,role
R800 T475 T476 amod critical,role
R801 T476 T473 dobj role,plays
R388 T491 T490 punct ",",IL-5
R389 T492 T490 cc and,IL-5
R390 T493 T490 conj IL-13,IL-5
R391 T494 T490 prep from,IL-5
R392 T495 T496 compound T,helper-2
R393 T496 T494 pobj helper-2,from
R394 T497 T496 punct (,helper-2
R395 T498 T496 appos Th2,helper-2
R396 T499 T496 punct ),helper-2
R397 T500 T494 pobj cells,from
R399 T501 T473 cc and,plays
R402 T502 T503 advmod therefore,is
R406 T503 T473 conj is,plays
R407 T504 T506 det a,mediator
R408 T505 T506 amod key,mediator
R409 T506 T503 attr mediator,is
R410 T507 T506 prep of,mediator
R411 T508 T509 amod allergic,diseases
R412 T509 T507 pobj diseases,of
R413 T510 T473 punct .,plays
R417 T511 T512 nsubj Corticosteroids,are
R420 T512 T512 ROOT are,are
R424 T513 T514 advmod highly,effective
R427 T514 T512 acomp effective,are
R431 T515 T514 prep in,effective

GO-BP

Id Subject Object Predicate Lexical cue
T757 608-620 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T758 745-755 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation

GO-MF

Id Subject Object Predicate Lexical cue
T770 442-447 http://purl.obolibrary.org/obo/GO_0005136 denotes IL)-4
T771 449-453 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T772 459-464 http://purl.obolibrary.org/obo/GO_0005144 denotes IL-13

GO-CC

Id Subject Object Predicate Lexical cue
T778 487-492 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T136 343-353 Sentence denotes Background
T137 354-546 Sentence denotes GATA-3 plays a critical role in regulating the expression of the cytokines interleukin (IL)-4, IL-5, and IL-13 from T helper-2 (Th2) cells and therefore is a key mediator of allergic diseases.
T138 547-662 Sentence denotes Corticosteroids are highly effective in suppressing allergic inflammation, but their effects on GATA-3 are unknown.
T139 663-800 Sentence denotes We investigated the effect of the corticosteroid fluticasone propionate on GATA-3 regulation in human T-lymphocytes in vitro and in vivo.
T140 802-822 Sentence denotes Methods and Findings
T3 50-215 Sentence denotes Peter Barnes and colleagues show that corticosteroids have a potent inhibitory effect on GATA-3 via two interacting mechanisms that suppress Th2 cytokine expression.
T4 216-332 Sentence denotes This novel mechanism of corticosteroid action may help explain the efficacy of corticosteroids in allergic diseases.
T5 334-342 Sentence denotes Abstract
T6 343-353 Sentence denotes Background
T7 354-546 Sentence denotes GATA-3 plays a critical role in regulating the expression of the cytokines interleukin (IL)-4, IL-5, and IL-13 from T helper-2 (Th2) cells and therefore is a key mediator of allergic diseases.
T8 547-662 Sentence denotes Corticosteroids are highly effective in suppressing allergic inflammation, but their effects on GATA-3 are unknown.
T9 663-800 Sentence denotes We investigated the effect of the corticosteroid fluticasone propionate on GATA-3 regulation in human T-lymphocytes in vitro and in vivo.
T10 802-822 Sentence denotes Methods and Findings

events-check-again

Id Subject Object Predicate Lexical cue
T879 354-360 Protein denotes GATA-3
T880 386-396 Regulation denotes regulating
T881 386-396 Regulation denotes regulating
T882 386-396 Regulation denotes regulating
T883 401-411 Gene_expression denotes expression
T884 401-411 Gene_expression denotes expression
T885 401-411 Gene_expression denotes expression
T886 429-447 Protein denotes interleukin (IL)-4
T887 449-453 Protein denotes IL-5
T888 459-464 Protein denotes IL-13
T889 643-649 Protein denotes GATA-3
T890 683-689 Regulation denotes effect
T891 738-744 Protein denotes GATA-3
T892 745-755 Regulation denotes regulation
R684 T884 T882 themeOf expression,regulating
R686 T885 T881 themeOf expression,regulating
R688 T886 T884 themeOf interleukin (IL)-4,expression
R689 T887 T883 themeOf IL-5,expression
R690 T888 T885 themeOf IL-13,expression
R692 T891 T892 themeOf GATA-3,regulation
R694 T892 T890 themeOf regulation,effect
R760 T879 T882 causeOf GATA-3,regulating
R762 T879 T880 causeOf GATA-3,regulating
R763 T879 T881 causeOf GATA-3,regulating
R766 T883 T880 themeOf expression,regulating

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T923 354-360 Protein denotes GATA-3
T924 429-453 Protein denotes interleukin (IL)-4, IL-5
T925 401-411 Gene_expression denotes expression
T926 386-396 Regulation denotes regulating
T927 643-649 Protein denotes GATA-3
T928 632-639 Regulation denotes effects
T929 738-744 Protein denotes GATA-3
T930 745-755 Regulation denotes regulation
T931 683-689 Regulation denotes effect
R739 T923 T926 causeOf GATA-3,regulating
R740 T924 T925 themeOf "interleukin (IL)-4, IL-5",expression
R742 T925 T926 themeOf expression,regulating
R743 T927 T928 themeOf GATA-3,effects
R744 T929 T930 themeOf GATA-3,regulation
R745 T930 T931 themeOf regulation,effect

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue
T96 386-396 Regulation denotes regulating
T97 386-396 Regulation denotes regulating
T98 386-396 Regulation denotes regulating
T99 401-411 Gene_expression denotes expression
T100 401-411 Gene_expression denotes expression
T101 401-411 Gene_expression denotes expression
T102 429-447 Protein denotes interleukin (IL)-4
T103 449-453 Protein denotes IL-5
T104 459-464 Protein denotes IL-13
T105 643-649 Protein denotes GATA-3
T106 683-689 Regulation denotes effect
T107 738-744 Protein denotes GATA-3
T108 745-755 Regulation denotes regulation
T95 354-360 Protein denotes GATA-3
R71 T99 T96 themeOf expression,regulating
R72 T100 T98 themeOf expression,regulating
R74 T102 T100 themeOf interleukin (IL)-4,expression
R774 T95 T98 causeOf GATA-3,regulating
R775 T95 T96 causeOf GATA-3,regulating
R73 T101 T97 themeOf expression,regulating
R75 T103 T99 themeOf IL-5,expression
R76 T104 T101 themeOf IL-13,expression
R77 T107 T108 themeOf GATA-3,regulation
R78 T108 T106 themeOf regulation,effect
R776 T95 T97 causeOf GATA-3,regulating

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T431 354-360 P23771 denotes GATA-3
T432 449-453 P05113 denotes IL-5
T433 459-464 P35225 denotes IL-13
T434 643-649 P23771 denotes GATA-3
T435 738-744 P23771 denotes GATA-3

test2

Id Subject Object Predicate Lexical cue
T52 354-360 Protein denotes GATA-3
T53 378-382 Regulation denotes role
T54 386-396 Regulation denotes regulating
T55 401-411 Gene_expression denotes expression
T56 429-447 Protein denotes interleukin (IL)-4
T57 449-453 Protein denotes IL-5
T58 459-464 Protein denotes IL-13
T59 632-639 Regulation denotes effects
T60 643-649 Protein denotes GATA-3
T61 738-744 Protein denotes GATA-3
T62 745-755 Regulation denotes regulation
R42 T52 T54 causeOf GATA-3,regulating
R43 T52 T53 causeOf GATA-3,role
R44 T55 T54 themeOf expression,regulating
R45 T56 T55 themeOf interleukin (IL)-4,expression
R46 T57 T55 themeOf IL-5,expression
R47 T58 T55 themeOf IL-13,expression
R48 T60 T59 themeOf GATA-3,effects
R49 T61 T62 themeOf GATA-3,regulation