PMC:2667511 / 9313-10113 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2667511","sourcedb":"PMC","sourceid":"2667511","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2667511","text":"Definition of interface and dom-face\nAn interface is a set of interacting atoms whose Solvent Accessible Surface Area (SASA) is decreased by \u003e 1 Å2 upon the formation of a complex [4]. The SASA for each atom was calculated using MSMS [26] with a probe sphere of radius 1.5 Å. Given a pair of interacting proteins, we define a set of interacting atoms for a single protomer as a face. An interface comprises a pair of interacting faces. We define the set of atoms comprising the face of a single domain as a dom-face. In order to calculate dom-faces, the interfaces extracted from complexes are mapped onto ranges of SCOP 1.65 domain definitions [23]. A total of 354 SCOP domains were extracted related to form the 147 protein complexes considered in our study of the different PPI types, see Table 1.","divisions":[{"label":"title","span":{"begin":0,"end":36}}],"tracks":[{"project":"2_test","denotations":[{"id":"19173748-9299342-8336753","span":{"begin":181,"end":182},"obj":"9299342"},{"id":"19173748-8906967-8336754","span":{"begin":235,"end":237},"obj":"8906967"},{"id":"19173748-14681400-8336755","span":{"begin":646,"end":648},"obj":"14681400"}],"attributes":[{"subj":"19173748-9299342-8336753","pred":"source","obj":"2_test"},{"subj":"19173748-8906967-8336754","pred":"source","obj":"2_test"},{"subj":"19173748-14681400-8336755","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ece993","default":true}]}]}}