PMC:2667511 / 7035-7805 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2667511","sourcedb":"PMC","sourceid":"2667511","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2667511","text":"The main aim of this work is to discover patterns, in the form of association rules, that characterize interaction sites in different PPI types. An important advantage of using such a classification approach is the interpretability of the final predictive model based on the analysis of the discovered set of rules. We give a detailed interpretation of discovered association rules in order to find common and specific patterns which are biologically significant and can be used to distinguish one PPI type from others. Here we focus on the prediction of four different PPI types (i.e. transient Enzyme inhibitor/Non Enzyme inhibitor and permanent homo/hetero obligomers), trying to gain more specific insights into the characterization of diverse kinds of interactions.","tracks":[]}