PMC:2664230 / 24572-24738
Annnotations
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T8369 | 80-93 | Negative_regulation | denotes | downregulates | |
T8370 | 94-99 | Protein | denotes | TNF-α | |
T8371 | 100-110 | Gene_expression | denotes | production | |
T8372 | 144-155 | Regulation | denotes | independent | true |
R6828 | T8369 | T8372 | themeOf | downregulates,independent | |
R6829 | T8370 | T8371 | themeOf | TNF-α,production | |
R6830 | T8371 | T8369 | themeOf | production,downregulates |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9621 | 0-2 | IN | denotes | In |
T9622 | 3-10 | NN | denotes | summary |
T9623 | 10-11 | , | denotes | , |
T9624 | 12-14 | PRP | denotes | we |
T9625 | 15-19 | VBP | denotes | have |
T9626 | 20-32 | VBN | denotes | demonstrated |
T9627 | 33-37 | IN | denotes | that |
T9628 | 38-41 | NNP | denotes | PDE |
T9629 | 42-52 | NN | denotes | inhibition |
T9630 | 53-55 | IN | denotes | of |
T9631 | 56-61 | JJ | denotes | human |
T9632 | 62-73 | NN | denotes | mononuclear |
T9633 | 74-79 | NNS | denotes | cells |
T9634 | 80-93 | VBZ | denotes | downregulates |
T9635 | 94-99 | JJ | denotes | TNF-α |
T9636 | 100-110 | NN | denotes | production |
T9637 | 110-111 | , | denotes | , |
T9638 | 112-114 | IN | denotes | at |
T9639 | 115-120 | JJS | denotes | least |
T9640 | 121-123 | IN | denotes | in |
T9641 | 124-128 | NN | denotes | part |
T9642 | 128-129 | , | denotes | , |
T9643 | 130-137 | IN | denotes | through |
T9644 | 138-139 | DT | denotes | a |
T9645 | 140-155 | JJ | denotes | PKA-independent |
T9646 | 156-165 | NN | denotes | mechanism |
T9647 | 165-166 | . | denotes | . |
R8042 | T9621 | T9626 | prep | In,demonstrated |
R8043 | T9622 | T9621 | pobj | summary,In |
R8044 | T9623 | T9626 | punct | ",",demonstrated |
R8045 | T9624 | T9626 | nsubj | we,demonstrated |
R8046 | T9625 | T9626 | aux | have,demonstrated |
R8047 | T9626 | T9626 | ROOT | demonstrated,demonstrated |
R8048 | T9627 | T9634 | mark | that,downregulates |
R8049 | T9628 | T9629 | compound | PDE,inhibition |
R8050 | T9629 | T9634 | nsubj | inhibition,downregulates |
R8051 | T9630 | T9629 | prep | of,inhibition |
R8052 | T9631 | T9633 | amod | human,cells |
R8053 | T9632 | T9633 | compound | mononuclear,cells |
R8054 | T9633 | T9630 | pobj | cells,of |
R8055 | T9634 | T9626 | ccomp | downregulates,demonstrated |
R8056 | T9635 | T9636 | compound | TNF-α,production |
R8057 | T9636 | T9634 | dobj | production,downregulates |
R8058 | T9637 | T9643 | punct | ",",through |
R8059 | T9638 | T9639 | advmod | at,least |
R8060 | T9639 | T9640 | advmod | least,in |
R8061 | T9640 | T9643 | prep | in,through |
R8062 | T9641 | T9640 | pobj | part,in |
R8063 | T9642 | T9643 | punct | ",",through |
R8064 | T9643 | T9634 | prep | through,downregulates |
R8065 | T9644 | T9646 | det | a,mechanism |
R8066 | T9645 | T9646 | amod | PKA-independent,mechanism |
R8067 | T9646 | T9643 | pobj | mechanism,through |
R8068 | T9647 | T9626 | punct | .,demonstrated |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9876 | 38-41 | http://purl.obolibrary.org/obo/GO_0004114 | denotes | PDE |
T9881 | 94-110 | http://purl.obolibrary.org/obo/GO_0032680 | denotes | TNF-α production |
T9887 | 94-110 | http://purl.obolibrary.org/obo/GO_0032640 | denotes | TNF-α production |
T9903 | 140-143 | http://purl.obolibrary.org/obo/GO_0004691 | denotes | PKA |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10032 | 38-41 | http://purl.obolibrary.org/obo/GO_0004114 | denotes | PDE |
T10044 | 140-143 | http://purl.obolibrary.org/obo/GO_0004691 | denotes | PKA |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10068 | 74-79 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10080 | 140-143 | http://purl.obolibrary.org/obo/GO_0005952 | denotes | PKA |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8408 | 0-166 | Sentence | denotes | In summary, we have demonstrated that PDE inhibition of human mononuclear cells downregulates TNF-α production, at least in part, through a PKA-independent mechanism. |
T164 | 0-166 | Sentence | denotes | In summary, we have demonstrated that PDE inhibition of human mononuclear cells downregulates TNF-α production, at least in part, through a PKA-independent mechanism. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T10652 | 80-93 | Negative_regulation | denotes | downregulates | |
T10653 | 94-99 | Protein | denotes | TNF-α | |
T10654 | 100-110 | Gene_expression | denotes | production | |
T10655 | 144-155 | Regulation | denotes | independent | true |
R8515 | T10652 | T10655 | themeOf | downregulates,independent | |
R8516 | T10653 | T10654 | themeOf | TNF-α,production | |
R8517 | T10654 | T10652 | themeOf | production,downregulates |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10295 | 38-41 | Protein | denotes | PDE |
T10296 | 94-99 | Protein | denotes | TNF-α |
T10297 | 140-143 | Protein | denotes | PKA |
T10298 | 42-52 | Negative_regulation | denotes | inhibition |
T10299 | 100-110 | Gene_expression | denotes | production |
T10300 | 80-93 | Negative_regulation | denotes | downregulates |
R8312 | T10295 | T10298 | themeOf | PDE,inhibition |
R8315 | T10296 | T10299 | themeOf | TNF-α,production |
R8316 | T10298 | T10300 | causeOf | inhibition,downregulates |
R8318 | T10299 | T10300 | themeOf | production,downregulates |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9810 | 94-97 | P01375 | denotes | TNF |
T9811 | 94-99 | P01375 | denotes | TNF-α |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8268 | 80-93 | Positive_regulation | denotes | downregulates |
T8269 | 94-99 | Protein | denotes | TNF-α |
T8270 | 100-110 | Gene_expression | denotes | production |
R6770 | T8269 | T8270 | themeOf | TNF-α,production |
R6771 | T8270 | T8268 | themeOf | production,downregulates |