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PMC:2664230 / 18501-18908 JSONTXT

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bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation
T8300 273-284 Negative_regulation denotes attenuation
T8301 288-293 Protein denotes TNF-α
T8302 294-304 Gene_expression denotes production
T8303 347-356 Positive_regulation denotes following
T8304 377-388 Regulation denotes independent true
R6789 T8300 T8303 themeOf attenuation,following
R6790 T8300 T8304 themeOf attenuation,independent
R6791 T8301 T8302 themeOf TNF-α,production
R6792 T8302 T8300 themeOf production,attenuation

2_test

Id Subject Object Predicate Lexical cue
18568240-12829247-22101125 212-213 12829247 denotes 6
18568240-15044179-22101125 212-213 15044179 denotes 6
18568240-15221855-22101125 212-213 15221855 denotes 6

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T8639 0-4 DT denotes This
T8640 5-12 JJ denotes classic
T8641 13-20 NN denotes pathway
T8642 21-24 VBZ denotes has
T8643 25-29 VBN denotes been
T8644 30-40 VBN denotes challenged
T8645 41-43 IN denotes as
T8646 44-47 DT denotes the
T8647 48-52 JJ denotes sole
T8648 53-62 NN denotes mechanism
T8649 63-71 VBN denotes involved
T8650 72-74 IN denotes in
T8651 75-78 DT denotes the
T8652 79-89 NN denotes modulation
T8653 90-92 IN denotes of
T8654 93-105 NN denotes inflammation
T8655 106-108 IN denotes by
T8656 109-123 JJ denotes cAMP-enhancing
T8657 124-129 NNS denotes drugs
T8658 129-130 , denotes ,
T8659 131-134 CC denotes and
T8660 135-146 JJ denotes alternative
T8661 147-157 NNS denotes mechanisms
T8662 158-167 VBG denotes involving
T8663 168-183 JJ denotes PKA-independent
T8664 184-192 NNS denotes pathways
T8665 193-197 VBP denotes have
T8666 198-202 VBN denotes been
T8667 203-211 VBN denotes proposed
T8668 211-213 CD denotes .6
T8669 214-215 CD denotes 8
T8670 216-218 IN denotes In
T8671 219-223 DT denotes this
T8672 224-230 NN denotes series
T8673 231-233 IN denotes of
T8674 234-245 NNS denotes experiments
T8675 245-246 , denotes ,
T8676 247-249 PRP denotes we
T8677 250-258 VBD denotes observed
T8678 259-260 DT denotes a
T8679 261-272 JJ denotes significant
T8680 273-284 NN denotes attenuation
T8681 285-287 IN denotes of
T8682 288-293 JJ denotes TNF-α
T8683 294-304 NN denotes production
T8684 305-307 IN denotes in
T8685 308-322 JJ denotes LPS-stimulated
T8686 323-328 JJ denotes human
T8687 329-340 NN denotes mononuclear
T8688 341-346 NNS denotes cells
T8689 347-356 VBG denotes following
T8690 357-360 NNP denotes PTX
T8691 361-375 NN denotes administration
T8692 375-376 , denotes ,
T8693 377-388 JJ denotes independent
T8694 389-391 IN denotes of
T8695 392-395 NNP denotes PKA
T8696 396-406 NN denotes activation
T8697 406-407 . denotes .
R7060 T8639 T8641 det This,pathway
R7061 T8640 T8641 amod classic,pathway
R7062 T8641 T8644 nsubjpass pathway,challenged
R7063 T8642 T8644 aux has,challenged
R7064 T8643 T8644 auxpass been,challenged
R7065 T8644 T8644 ROOT challenged,challenged
R7066 T8645 T8644 prep as,challenged
R7067 T8646 T8648 det the,mechanism
R7068 T8647 T8648 amod sole,mechanism
R7069 T8648 T8645 pobj mechanism,as
R7070 T8649 T8648 acl involved,mechanism
R7071 T8650 T8649 prep in,involved
R7072 T8651 T8652 det the,modulation
R7073 T8652 T8650 pobj modulation,in
R7074 T8653 T8652 prep of,modulation
R7075 T8654 T8653 pobj inflammation,of
R7076 T8655 T8649 agent by,involved
R7077 T8656 T8657 amod cAMP-enhancing,drugs
R7078 T8657 T8655 pobj drugs,by
R7079 T8658 T8657 punct ",",drugs
R7080 T8659 T8657 cc and,drugs
R7081 T8660 T8661 amod alternative,mechanisms
R7082 T8661 T8657 conj mechanisms,drugs
R7083 T8662 T8661 acl involving,mechanisms
R7084 T8663 T8664 amod PKA-independent,pathways
R7085 T8664 T8662 dobj pathways,involving
R7086 T8665 T8667 aux have,proposed
R7087 T8666 T8667 auxpass been,proposed
R7088 T8667 T8644 conj proposed,challenged
R7089 T8668 T8667 dobj .6,proposed
R7090 T8669 T8667 prep 8,proposed
R7091 T8670 T8677 prep In,observed
R7092 T8671 T8672 det this,series
R7093 T8672 T8670 pobj series,In
R7094 T8673 T8672 prep of,series
R7095 T8674 T8673 pobj experiments,of
R7096 T8675 T8677 punct ",",observed
R7097 T8676 T8677 nsubj we,observed
R7098 T8677 T8677 ROOT observed,observed
R7099 T8678 T8680 det a,attenuation
R7100 T8679 T8680 amod significant,attenuation
R7101 T8680 T8677 dobj attenuation,observed
R7102 T8681 T8680 prep of,attenuation
R7103 T8682 T8683 amod TNF-α,production
R7104 T8683 T8681 pobj production,of
R7105 T8684 T8683 prep in,production
R7106 T8685 T8688 amod LPS-stimulated,cells
R7107 T8686 T8688 amod human,cells
R7108 T8687 T8688 compound mononuclear,cells
R7109 T8688 T8684 pobj cells,in
R7110 T8689 T8688 acl following,cells
R7111 T8690 T8691 compound PTX,administration
R7112 T8691 T8689 dobj administration,following
R7113 T8692 T8691 punct ",",administration
R7114 T8693 T8691 amod independent,administration
R7115 T8694 T8693 prep of,independent
R7116 T8695 T8696 compound PKA,activation
R7117 T8696 T8694 pobj activation,of
R7118 T8697 T8677 punct .,observed

GO-BP

Id Subject Object Predicate Lexical cue
T9871 93-105 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T9879 288-304 http://purl.obolibrary.org/obo/GO_0032680 denotes TNF-α production
T9885 288-304 http://purl.obolibrary.org/obo/GO_0032640 denotes TNF-α production
T9896 168-171 http://purl.obolibrary.org/obo/GO_0004691 denotes PKA
T9897 392-395 http://purl.obolibrary.org/obo/GO_0004691 denotes PKA

GO-MF

Id Subject Object Predicate Lexical cue
T10037 168-171 http://purl.obolibrary.org/obo/GO_0004691 denotes PKA
T10038 392-395 http://purl.obolibrary.org/obo/GO_0004691 denotes PKA

GO-CC

Id Subject Object Predicate Lexical cue
T10063 341-346 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T10073 168-171 http://purl.obolibrary.org/obo/GO_0005952 denotes PKA
T10074 392-395 http://purl.obolibrary.org/obo/GO_0005952 denotes PKA

sentences

Id Subject Object Predicate Lexical cue
T8381 0-407 Sentence denotes This classic pathway has been challenged as the sole mechanism involved in the modulation of inflammation by cAMP-enhancing drugs, and alternative mechanisms involving PKA-independent pathways have been proposed.6–8 In this series of experiments, we observed a significant attenuation of TNF-α production in LPS-stimulated human mononuclear cells following PTX administration, independent of PKA activation.
T137 0-407 Sentence denotes This classic pathway has been challenged as the sole mechanism involved in the modulation of inflammation by cAMP-enhancing drugs, and alternative mechanisms involving PKA-independent pathways have been proposed.6–8 In this series of experiments, we observed a significant attenuation of TNF-α production in LPS-stimulated human mononuclear cells following PTX administration, independent of PKA activation.

events-check-again

Id Subject Object Predicate Lexical cue Negation
T10107 273-284 Negative_regulation denotes attenuation
T10108 288-293 Protein denotes TNF-α
T10585 294-304 Gene_expression denotes production
T10586 347-356 Positive_regulation denotes following
T10587 377-388 Regulation denotes independent true
R8198 T10107 T10586 themeOf attenuation,following
R8199 T10107 T10587 themeOf attenuation,independent
R8200 T10108 T10585 themeOf TNF-α,production
R8432 T10585 T10107 themeOf production,attenuation

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T10137 168-171 Protein denotes PKA
T10138 288-293 Protein denotes TNF-α
T10139 392-395 Protein denotes PKA
T10140 294-304 Gene_expression denotes production
T10141 396-406 Positive_regulation denotes activation
T10142 273-284 Negative_regulation denotes attenuation
R8220 T10138 T10140 themeOf TNF-α,production
R8221 T10139 T10141 themeOf PKA,activation
R8222 T10140 T10142 themeOf production,attenuation

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T9721 288-291 P01375 denotes TNF
T9722 288-293 P01375 denotes TNF-α

test2

Id Subject Object Predicate Lexical cue
T8198 273-284 Negative_regulation denotes attenuation
T8199 288-293 Protein denotes TNF-α
T8200 294-304 Gene_expression denotes production
R6727 T8199 T8200 themeOf TNF-α,production
R6728 T8200 T8198 themeOf production,attenuation