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PMC:2626671 / 2264-2761 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T1686 0-12 RB denotes Nevertheless
T1687 12-13 -COMMA- denotes ,
T1688 14-17 DT denotes the
T1689 18-26 JJ denotes specific
T1690 27-32 NN denotes roles
T1691 33-35 IN denotes of
T1692 36-41 NN denotes T-bet
T1693 42-45 CC denotes and
T1694 46-51 NN denotes Eomes
T1695 52-54 IN denotes in
T1696 55-61 JJ denotes clonal
T1697 62-71 NN denotes expansion
T1698 72-75 CC denotes and
T1699 76-79 NN denotes CTL
T1700 80-95 NN denotes differentiation
T1701 96-100 VB denotes have
T1702 101-104 RB denotes not
T1703 105-108 RB denotes yet
T1704 109-113 VB denotes been
T1705 114-122 VB denotes resolved
T1706 122-123 -COLON- denotes :
T1707 124-126 IN denotes in
T1708 127-137 JJ denotes particular
T1709 137-138 -COMMA- denotes ,
T1710 139-141 PRP denotes it
T1711 142-144 VB denotes is
T1712 145-148 RB denotes not
T1713 149-154 VB denotes known
T1714 155-162 IN denotes whether
T1715 163-168 DT denotes these
T1716 169-182 NN denotes transcription
T1717 183-190 NN denotes factors
T1718 191-199 VB denotes function
T1719 200-211 RB denotes redundantly
T1720 212-214 TO denotes to
T1721 215-222 VB denotes control
T1722 223-231 NN denotes effector
T1723 232-238 NN denotes CD8+ T
T1724 239-243 NN denotes cell
T1725 244-259 NN denotes differentiation
T1726 259-260 -COMMA- denotes ,
T1727 261-264 CC denotes and
T1728 265-272 IN denotes whether
T1729 273-277 PRP denotes they
T1730 278-280 VB denotes do
T1731 281-283 RB denotes so
T1732 284-292 RB denotes directly
T1733 293-295 IN denotes by
T1734 296-305 VB denotes targeting
T1735 306-314 JJ denotes specific
T1736 315-323 NN denotes effector
T1737 324-332 NN denotes cytokine
T1738 333-336 CC denotes and
T1739 337-346 JJ denotes cytolytic
T1740 347-358 NN denotes genes. Runx
T1741 359-367 NN denotes proteins
T1742 367-368 -COMMA- denotes ,
T1743 369-370 DT denotes a
T1744 371-377 NN denotes family
T1745 378-380 IN denotes of
T1746 381-386 CD denotes three
T1747 387-398 JJ denotes DNA-binding
T1748 399-412 NN denotes transcription
T1749 413-420 NN denotes factors
T1750 420-421 -COMMA- denotes ,
T1751 422-429 NN denotes control
T1752 430-439 NN denotes thymocyte
T1753 440-455 NN denotes differentiation
T1754 456-459 CC denotes and
T1755 460-463 DT denotes the
T1756 464-471 NN denotes CD4/CD8
T1757 472-479 NN denotes lineage
T1758 480-488 NN denotes decision
T1759 489-490 -LRB- denotes (
T1760 490-495 CD denotes 10–13
T1761 495-496 -RRB- denotes )
R1343 T1705 T1686 arg1Of resolved,Nevertheless
R1353 T1705 T1687 arg1Of resolved,","
R1354 T1705 T1701 arg2Of resolved,have
R1359 T1705 T1702 arg1Of resolved,not
R1360 T1705 T1703 arg1Of resolved,yet
R1361 T1705 T1704 arg2Of resolved,been
R1362 T1705 T1706 arg1Of resolved,:
R1366 T1708 T1707 arg2Of particular,in
R1370 T1710 T1711 arg1Of it,is
R1376 T1710 T1713 arg2Of it,known
R1377 T1713 T1706 arg2Of known,:
R1384 T1713 T1707 arg1Of known,in
R1385 T1713 T1709 arg1Of known,","
R1389 T1713 T1711 arg2Of known,is
R1390 T1713 T1712 arg1Of known,not
R1391 T1717 T1715 arg1Of factors,these
R1409 T1717 T1716 arg1Of factors,transcription
R1410 T1717 T1718 arg1Of factors,function
R1413 T1717 T1721 arg1Of factors,control
R1414 T1718 T1714 arg1Of function,whether
R1419 T1718 T1719 arg1Of function,redundantly
R1422 T1718 T1720 modOf function,to
R1424 T1718 T1727 arg1Of function,and
R1426 T1721 T1720 arg1Of control,to
R1432 T1725 T1721 arg2Of differentiation,control
R1442 T1725 T1722 arg1Of differentiation,effector
R1444 T1725 T1723 arg1Of differentiation,CD8+ T
R1445 T1725 T1724 arg1Of differentiation,cell
R1446 T1727 T1713 arg3Of and,known
R1447 T1690 T1688 arg1Of roles,the
R1448 T1690 T1689 arg1Of roles,specific
R1449 T1690 T1691 arg1Of roles,of
R1450 T1690 T1695 arg1Of roles,in
R1451 T1690 T1701 arg1Of roles,have
R1452 T1690 T1704 arg1Of roles,been
R1453 T1690 T1705 arg2Of roles,resolved
R1454 T1692 T1693 arg1Of T-bet,and
R1455 T1693 T1691 arg2Of and,of
R1456 T1694 T1693 arg2Of Eomes,and
R1457 T1727 T1726 arg1Of and,","
R1458 T1697 T1696 arg1Of expansion,clonal
R1459 T1697 T1698 arg1Of expansion,and
R1460 T1728 T1727 arg2Of whether,and
R1461 T1698 T1695 arg2Of and,in
R1462 T1700 T1698 arg2Of differentiation,and
R1463 T1729 T1730 arg1Of they,do
R1464 T1700 T1699 arg1Of differentiation,CTL
R1465 T1730 T1728 arg2Of do,whether
R1466 T1730 T1731 arg1Of do,so
R1467 T1730 T1732 arg1Of do,directly
R1468 T1730 T1733 arg1Of do,by
R1469 T1734 T1733 arg2Of targeting,by
R1470 T1737 T1735 arg1Of cytokine,specific
R1477 T1737 T1736 arg1Of cytokine,effector
R1478 T1737 T1738 arg1Of cytokine,and
R1480 T1738 T1734 arg2Of and,targeting
R1483 T1738 T1742 arg1Of and,","
R1488 T1738 T1750 arg1Of and,","
R1491 T1741 T1738 arg2Of proteins,and
R1497 T1741 T1739 arg1Of proteins,cytolytic
R1504 T1741 T1740 arg1Of proteins,"genes. Runx"
R1505 T1744 T1742 arg2Of family,","
R1509 T1744 T1743 arg1Of family,a
R1510 T1744 T1745 arg1Of family,of
R1511 T1749 T1745 arg2Of factors,of
R1527 T1749 T1746 arg1Of factors,three
R1529 T1749 T1747 arg1Of factors,DNA-binding
R1530 T1749 T1748 arg1Of factors,transcription
R1532 T1753 T1751 arg1Of differentiation,control
R1537 T1753 T1752 arg1Of differentiation,thymocyte
R1542 T1753 T1754 arg1Of differentiation,and
R1544 T1754 T1750 arg2Of and,","
R1547 T1758 T1754 arg2Of decision,and
R1553 T1758 T1755 arg1Of decision,the
R1554 T1758 T1756 arg1Of decision,CD4/CD8
R1555 T1758 T1757 arg1Of decision,lineage
R1560 T1758 T1759 arg1Of decision,(
R1563 T1760 T1759 arg2Of 10–13,(
R1566 T1761 T1759 arg3Of ),(

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T1995 273-277 Anaphor denotes they
T1996 36-41 Antecedent denotes T-bet
T1997 46-51 Antecedent denotes Eomes
R1717 T1995 T1996 boundBy they,T-bet
R1725 T1995 T1997 boundBy they,Eomes

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T1074 0-12 RB denotes Nevertheless
T1075 12-13 , denotes ,
T1076 14-17 DT denotes the
T1077 18-26 JJ denotes specific
T1078 27-32 NNS denotes roles
T1079 33-35 IN denotes of
T1080 36-41 NN denotes T-bet
T1081 42-45 CC denotes and
T1082 46-51 NNS denotes Eomes
T1083 52-54 IN denotes in
T1084 55-61 JJ denotes clonal
T1085 62-71 NN denotes expansion
T1086 72-75 CC denotes and
T1087 76-79 NNP denotes CTL
T1088 80-95 NN denotes differentiation
T1089 96-100 VBP denotes have
T1090 101-104 RB denotes not
T1091 105-108 RB denotes yet
T1092 109-113 VBN denotes been
T1093 114-122 VBN denotes resolved
T1094 122-123 : denotes :
T1095 124-126 IN denotes in
T1096 127-137 JJ denotes particular
T1097 137-138 , denotes ,
T1098 139-141 PRP denotes it
T1099 142-144 VBZ denotes is
T1100 145-148 RB denotes not
T1101 149-154 VBN denotes known
T1102 155-162 IN denotes whether
T1103 163-168 DT denotes these
T1104 169-182 NN denotes transcription
T1105 183-190 NNS denotes factors
T1106 191-199 VBP denotes function
T1107 200-211 RB denotes redundantly
T1108 212-214 TO denotes to
T1109 215-222 VB denotes control
T1110 223-231 JJ denotes effector
T1111 232-235 NNP denotes CD8
T1112 235-236 CD denotes +
T1113 237-238 NNP denotes T
T1114 239-243 NN denotes cell
T1115 244-259 NN denotes differentiation
T1116 259-260 , denotes ,
T1117 261-264 CC denotes and
T1118 265-272 IN denotes whether
T1119 273-277 PRP denotes they
T1120 278-280 VBP denotes do
T1121 281-283 RB denotes so
T1122 284-292 RB denotes directly
T1123 293-295 IN denotes by
T1124 296-305 VBG denotes targeting
T1125 306-314 JJ denotes specific
T1126 315-323 NN denotes effector
T1127 324-332 NN denotes cytokine
T1128 333-336 CC denotes and
T1129 337-346 JJ denotes cytolytic
T1130 347-358 NNP denotes genes. Runx
T1131 359-367 NNS denotes proteins
T1132 367-368 , denotes ,
T1133 369-370 DT denotes a
T1134 371-377 NN denotes family
T1135 378-380 IN denotes of
T1136 381-386 CD denotes three
T1137 387-398 JJ denotes DNA-binding
T1138 399-412 NN denotes transcription
T1139 413-420 NNS denotes factors
T1140 420-421 , denotes ,
T1141 422-429 NN denotes control
T1142 430-439 NN denotes thymocyte
T1143 440-455 NN denotes differentiation
T1144 456-459 CC denotes and
T1145 460-463 DT denotes the
T1146 464-471 NNP denotes CD4/CD8
T1147 472-479 NN denotes lineage
T1148 480-488 NN denotes decision
T1149 489-490 -LRB- denotes (
T1150 490-492 CD denotes 10
T1151 493-495 CD denotes 13
T1152 495-496 -RRB- denotes )
T1153 496-497 . denotes .
R840 T1074 T1093 advmod Nevertheless,resolved
R841 T1075 T1093 punct ",",resolved
R842 T1076 T1078 det the,roles
R843 T1077 T1078 amod specific,roles
R844 T1078 T1093 nsubj roles,resolved
R845 T1079 T1078 prep of,roles
R846 T1080 T1079 pobj T-bet,of
R847 T1081 T1080 cc and,T-bet
R848 T1082 T1080 conj Eomes,T-bet
R849 T1083 T1082 prep in,Eomes
R850 T1084 T1085 amod clonal,expansion
R851 T1085 T1083 pobj expansion,in
R852 T1086 T1085 cc and,expansion
R853 T1087 T1088 compound CTL,differentiation
R854 T1088 T1085 conj differentiation,expansion
R855 T1089 T1093 aux have,resolved
R856 T1090 T1093 neg not,resolved
R857 T1091 T1093 advmod yet,resolved
R858 T1092 T1093 auxpass been,resolved
R859 T1093 T1101 ccomp resolved,known
R860 T1094 T1101 punct :,known
R861 T1095 T1101 prep in,known
R862 T1096 T1095 amod particular,in
R863 T1097 T1101 punct ",",known
R864 T1098 T1101 nsubjpass it,known
R865 T1099 T1101 auxpass is,known
R866 T1100 T1101 neg not,known
R867 T1101 T1101 ROOT known,known
R868 T1102 T1106 mark whether,function
R869 T1103 T1105 det these,factors
R870 T1104 T1105 compound transcription,factors
R871 T1105 T1106 nsubj factors,function
R872 T1106 T1101 ccomp function,known
R873 T1107 T1106 advmod redundantly,function
R874 T1108 T1109 aux to,control
R875 T1109 T1106 xcomp control,function
R876 T1110 T1115 amod effector,differentiation
R877 T1111 T1115 nmod CD8,differentiation
R878 T1112 T1115 nummod +,differentiation
R879 T1113 T1114 compound T,cell
R880 T1114 T1115 compound cell,differentiation
R881 T1115 T1109 dobj differentiation,control
R882 T1116 T1106 punct ",",function
R883 T1117 T1106 cc and,function
R884 T1118 T1120 mark whether,do
R885 T1119 T1120 nsubj they,do
R886 T1120 T1106 conj do,function
R887 T1121 T1122 advmod so,directly
R888 T1122 T1120 advmod directly,do
R889 T1123 T1120 prep by,do
R890 T1124 T1123 pcomp targeting,by
R891 T1125 T1127 amod specific,cytokine
R892 T1126 T1127 compound effector,cytokine
R893 T1127 T1124 dobj cytokine,targeting
R894 T1128 T1127 cc and,cytokine
R895 T1129 T1131 amod cytolytic,proteins
R896 T1130 T1131 compound "genes. Runx",proteins
R897 T1131 T1127 conj proteins,cytokine
R898 T1132 T1131 punct ",",proteins
R899 T1133 T1134 det a,family
R900 T1134 T1131 conj family,proteins
R901 T1135 T1134 prep of,family
R902 T1136 T1139 nummod three,factors
R903 T1137 T1139 amod DNA-binding,factors
R904 T1138 T1139 compound transcription,factors
R905 T1139 T1135 pobj factors,of
R906 T1140 T1139 punct ",",factors
R907 T1141 T1143 compound control,differentiation
R908 T1142 T1143 compound thymocyte,differentiation
R909 T1143 T1139 appos differentiation,factors
R910 T1144 T1143 cc and,differentiation
R911 T1145 T1148 det the,decision
R912 T1146 T1148 compound CD4/CD8,decision
R913 T1147 T1148 compound lineage,decision
R914 T1148 T1143 conj decision,differentiation
R915 T1149 T1151 punct (,13
R916 T1150 T1151 nummod 10,13
R917 T1151 T1148 appos 13,decision
R918 T1152 T1139 punct ),factors
R919 T1153 T1101 punct .,known

GO-BP

Id Subject Object Predicate Lexical cue
T825 430-455 http://purl.obolibrary.org/obo/GO_0033077 denotes thymocyte differentiation
T862 237-259 http://purl.obolibrary.org/obo/GO_0043379 denotes T cell differentiation
T865 239-259 http://purl.obolibrary.org/obo/GO_0030154 denotes cell differentiation
T873 169-182 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T874 399-412 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T844 237-259 http://purl.obolibrary.org/obo/GO_0002572 denotes T cell differentiation
T847 237-259 http://purl.obolibrary.org/obo/GO_0045580 denotes T cell differentiation
T850 237-259 http://purl.obolibrary.org/obo/GO_0001865 denotes T cell differentiation
T853 237-259 http://purl.obolibrary.org/obo/GO_0030217 denotes T cell differentiation
T856 237-259 http://purl.obolibrary.org/obo/GO_0042093 denotes T cell differentiation
T859 237-259 http://purl.obolibrary.org/obo/GO_0045066 denotes T cell differentiation

GO-MF

Id Subject Object Predicate Lexical cue
T2073 387-398 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA-binding
T2074 391-398 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T2075 391-420 http://purl.obolibrary.org/obo/GO_0008134 denotes binding transcription factors
T2076 391-420 http://purl.obolibrary.org/obo/GO_0033613 denotes binding transcription factors
T2077 391-420 http://purl.obolibrary.org/obo/GO_0043425 denotes binding transcription factors
T2078 391-420 http://purl.obolibrary.org/obo/GO_0070491 denotes binding transcription factors

sentences

Id Subject Object Predicate Lexical cue
T833 0-497 Sentence denotes Nevertheless, the specific roles of T-bet and Eomes in clonal expansion and CTL differentiation have not yet been resolved: in particular, it is not known whether these transcription factors function redundantly to control effector CD8+ T cell differentiation, and whether they do so directly by targeting specific effector cytokine and cytolytic genes. Runx proteins, a family of three DNA-binding transcription factors, control thymocyte differentiation and the CD4/CD8 lineage decision (10–13).
T15 0-353 Sentence denotes Nevertheless, the specific roles of T-bet and Eomes in clonal expansion and CTL differentiation have not yet been resolved: in particular, it is not known whether these transcription factors function redundantly to control effector CD8+ T cell differentiation, and whether they do so directly by targeting specific effector cytokine and cytolytic genes.
T16 354-497 Sentence denotes Runx proteins, a family of three DNA-binding transcription factors, control thymocyte differentiation and the CD4/CD8 lineage decision (10–13).

events-check-again

Id Subject Object Predicate Lexical cue
T2578 36-41 Protein denotes T-bet
T2579 46-51 Protein denotes Eomes
T2580 232-235 Protein denotes CD8
T2581 296-305 Binding denotes targeting
T2582 296-305 Binding denotes targeting
T2583 464-467 Protein denotes CD4
T2584 468-471 Protein denotes CD8
R2013 T2578 T2581 themeOf T-bet,targeting
R2014 T2579 T2582 themeOf Eomes,targeting

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue
T1442 296-305 Binding denotes targeting
T1443 296-305 Binding denotes targeting
T1451 36-41 Protein denotes T-bet
T1452 46-51 Protein denotes Eomes
T1453 232-235 Protein denotes CD8
T1454 464-467 Protein denotes CD4
T1456 468-471 Protein denotes CD8
R1186 T1451 T1442 themeOf T-bet,targeting
R1187 T1452 T1443 themeOf Eomes,targeting

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T2013 36-41 Q9UL17 denotes T-bet
T2014 46-51 O95936 denotes Eomes
T2015 232-235 P10966 denotes CD8
T2016 232-235 P01732 denotes CD8
T2017 354-358 Q01196 denotes Runx
T2018 354-358 Q13761 denotes Runx
T2019 354-358 Q13950 denotes Runx
T2020 464-467 P01730 denotes CD4
T2021 468-471 P10966 denotes CD8
T2022 468-471 P01732 denotes CD8

test2

Id Subject Object Predicate Lexical cue
T762 36-41 Protein denotes T-bet
T763 46-51 Protein denotes Eomes
T764 232-235 Protein denotes CD8
T765 464-467 Protein denotes CD4
T766 468-471 Protein denotes CD8