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{"project":"events-check-again","denotations":[{"id":"T23765","span":{"begin":27,"end":33},"obj":"Positive_regulation"},{"id":"T23766","span":{"begin":34,"end":39},"obj":"Protein"},{"id":"T23767","span":{"begin":40,"end":50},"obj":"Gene_expression"},{"id":"T23768","span":{"begin":106,"end":109},"obj":"Protein"},{"id":"T23769","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T23770","span":{"begin":131,"end":136},"obj":"Protein"},{"id":"T23771","span":{"begin":210,"end":215},"obj":"Protein"},{"id":"T23772","span":{"begin":386,"end":389},"obj":"Protein"},{"id":"T23773","span":{"begin":390,"end":394},"obj":"Protein"},{"id":"T23774","span":{"begin":396,"end":401},"obj":"Protein"},{"id":"T23775","span":{"begin":411,"end":415},"obj":"Protein"}],"relations":[{"id":"R17831","pred":"themeOf","subj":"T23766","obj":"T23767"},{"id":"R17832","pred":"themeOf","subj":"T23767","obj":"T23765"}],"attributes":[{"id":"M497","pred":"Negation","subj":"T23765","obj":"true"}],"text":"Figure 1 Th2 Cells Cannot Induce FOXP3 Expression\n(A) Human T cells were activated with plate-bound anti-CD3/CD28 with or without TGF-β as indicated on the x-axis of (B). Cells were harvested after 5 days and FOXP3 mRNA was quantified by real-time PCR. Bars show the mean ± SD of 4 independent experiments.\n(B) In vitro differentiated Th1, Th2, or iTreg cells were activated with anti-CD3/CD28, TGF-β, or anti-IL-4 as indicated. The phenotype of these cells was confirmed by FACS and proliferation analysis (Figure S1). Bars show the mean ± SD of four independent experiments. "}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T23721","span":{"begin":101,"end":109},"obj":"Protein"},{"id":"T23722","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T23723","span":{"begin":131,"end":136},"obj":"Protein"},{"id":"T23724","span":{"begin":210,"end":220},"obj":"Protein"},{"id":"T23725","span":{"begin":381,"end":389},"obj":"Protein"},{"id":"T23726","span":{"begin":390,"end":394},"obj":"Protein"},{"id":"T23727","span":{"begin":396,"end":401},"obj":"Protein"},{"id":"T23728","span":{"begin":406,"end":415},"obj":"Protein"}],"text":"Figure 1 Th2 Cells Cannot Induce FOXP3 Expression\n(A) Human T cells were activated with plate-bound anti-CD3/CD28 with or without TGF-β as indicated on the x-axis of (B). Cells were harvested after 5 days and FOXP3 mRNA was quantified by real-time PCR. Bars show the mean ± SD of 4 independent experiments.\n(B) In vitro differentiated Th1, Th2, or iTreg cells were activated with anti-CD3/CD28, TGF-β, or anti-IL-4 as indicated. The phenotype of these cells was confirmed by FACS and proliferation analysis (Figure S1). Bars show the mean ± SD of four independent experiments. "}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T23452","span":{"begin":210,"end":215},"obj":"Protein"},{"id":"T23453","span":{"begin":386,"end":389},"obj":"Protein"},{"id":"T23454","span":{"begin":390,"end":394},"obj":"Protein"},{"id":"T23455","span":{"begin":396,"end":401},"obj":"Protein"},{"id":"T23456","span":{"begin":411,"end":415},"obj":"Protein"},{"id":"T23446","span":{"begin":27,"end":33},"obj":"Positive_regulation"},{"id":"T23447","span":{"begin":34,"end":39},"obj":"Protein"},{"id":"T23448","span":{"begin":40,"end":50},"obj":"Gene_expression"},{"id":"T23449","span":{"begin":106,"end":109},"obj":"Protein"},{"id":"T23450","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T23451","span":{"begin":131,"end":136},"obj":"Protein"}],"relations":[{"id":"R17593","pred":"themeOf","subj":"T23447","obj":"T23448"},{"id":"R17594","pred":"themeOf","subj":"T23448","obj":"T23446"}],"attributes":[{"id":"M492","pred":"Negation","subj":"T23446","obj":"true"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Figure 1 Th2 Cells Cannot Induce FOXP3 Expression\n(A) Human T cells were activated with plate-bound anti-CD3/CD28 with or without TGF-β as indicated on the x-axis of (B). Cells were harvested after 5 days and FOXP3 mRNA was quantified by real-time PCR. Bars show the mean ± SD of 4 independent experiments.\n(B) In vitro differentiated Th1, Th2, or iTreg cells were activated with anti-CD3/CD28, TGF-β, or anti-IL-4 as indicated. The phenotype of these cells was confirmed by FACS and proliferation analysis (Figure S1). Bars show the mean ± SD of four independent experiments. "}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T23569","span":{"begin":34,"end":39},"obj":"Q9BZS1"},{"id":"T23570","span":{"begin":106,"end":109},"obj":"P04234"},{"id":"T23571","span":{"begin":106,"end":109},"obj":"P20963"},{"id":"T23572","span":{"begin":106,"end":109},"obj":"P09693"},{"id":"T23573","span":{"begin":106,"end":109},"obj":"P07766"},{"id":"T23574","span":{"begin":110,"end":114},"obj":"P10747"},{"id":"T23575","span":{"begin":131,"end":136},"obj":"P01137"},{"id":"T23576","span":{"begin":210,"end":215},"obj":"Q9BZS1"},{"id":"T23577","span":{"begin":386,"end":389},"obj":"P09693"},{"id":"T23578","span":{"begin":386,"end":389},"obj":"P20963"},{"id":"T23579","span":{"begin":386,"end":389},"obj":"P07766"},{"id":"T23580","span":{"begin":386,"end":389},"obj":"P04234"},{"id":"T23581","span":{"begin":390,"end":394},"obj":"P10747"},{"id":"T23582","span":{"begin":396,"end":401},"obj":"P01137"},{"id":"T23583","span":{"begin":411,"end":415},"obj":"P05112"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Figure 1 Th2 Cells Cannot Induce FOXP3 Expression\n(A) Human T cells were activated with plate-bound anti-CD3/CD28 with or without TGF-β as indicated on the x-axis of (B). Cells were harvested after 5 days and FOXP3 mRNA was quantified by real-time PCR. Bars show the mean ± SD of 4 independent experiments.\n(B) In vitro differentiated Th1, Th2, or iTreg cells were activated with anti-CD3/CD28, TGF-β, or anti-IL-4 as indicated. The phenotype of these cells was confirmed by FACS and proliferation analysis (Figure S1). Bars show the mean ± SD of four independent experiments. "}

{"project":"test2","denotations":[{"id":"T23439","span":{"begin":27,"end":33},"obj":"Positive_regulation"},{"id":"T23440","span":{"begin":34,"end":39},"obj":"Protein"},{"id":"T23441","span":{"begin":40,"end":50},"obj":"Gene_expression"},{"id":"T23442","span":{"begin":106,"end":109},"obj":"Protein"},{"id":"T23443","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T23444","span":{"begin":131,"end":136},"obj":"Protein"},{"id":"T23445","span":{"begin":210,"end":215},"obj":"Protein"}],"relations":[{"id":"R17591","pred":"themeOf","subj":"T23440","obj":"T23441"},{"id":"R17592","pred":"themeOf","subj":"T23441","obj":"T23439"}],"attributes":[{"id":"M491","pred":"Negation","subj":"T23439","obj":"true"}],"text":"Figure 1 Th2 Cells Cannot Induce FOXP3 Expression\n(A) Human T cells were activated with plate-bound anti-CD3/CD28 with or without TGF-β as indicated on the x-axis of (B). Cells were harvested after 5 days and FOXP3 mRNA was quantified by real-time PCR. Bars show the mean ± SD of 4 independent experiments.\n(B) In vitro differentiated Th1, Th2, or iTreg cells were activated with anti-CD3/CD28, TGF-β, or anti-IL-4 as indicated. The phenotype of these cells was confirmed by FACS and proliferation analysis (Figure S1). Bars show the mean ± SD of four independent experiments. "}