PMC:2222968 / 30146-30458 JSONTXT

Annnotations TAB JSON ListView MergeView

    pmc-enju-pas

    {"project":"pmc-enju-pas","denotations":[{"id":"T14137","span":{"begin":0,"end":3},"obj":"CC"},{"id":"T14138","span":{"begin":4,"end":9},"obj":"IN"},{"id":"T14139","span":{"begin":10,"end":11},"obj":"DT"},{"id":"T14140","span":{"begin":12,"end":23},"obj":"NN"},{"id":"T14141","span":{"begin":24,"end":26},"obj":"IN"},{"id":"T14142","span":{"begin":27,"end":32},"obj":"NN"},{"id":"T14143","span":{"begin":33,"end":36},"obj":"CC"},{"id":"T14144","span":{"begin":37,"end":42},"obj":"NN"},{"id":"T14145","span":{"begin":43,"end":48},"obj":"NN"},{"id":"T14146","span":{"begin":49,"end":51},"obj":"VB"},{"id":"T14147","span":{"begin":52,"end":61},"obj":"RB"},{"id":"T14148","span":{"begin":62,"end":65},"obj":"RB"},{"id":"T14149","span":{"begin":66,"end":74},"obj":"JJ"},{"id":"T14150","span":{"begin":74,"end":75},"obj":"-COMMA-"},{"id":"T14151","span":{"begin":76,"end":83},"obj":"IN"},{"id":"T14152","span":{"begin":84,"end":89},"obj":"NN"},{"id":"T14153","span":{"begin":90,"end":95},"obj":"NN"},{"id":"T14154","span":{"begin":96,"end":100},"obj":"RB"},{"id":"T14155","span":{"begin":101,"end":112},"obj":"RB"},{"id":"T14156","span":{"begin":113,"end":120},"obj":"VB"},{"id":"T14157","span":{"begin":121,"end":125},"obj":"NN"},{"id":"T14158","span":{"begin":126,"end":131},"obj":"IN"},{"id":"T14159","span":{"begin":132,"end":142},"obj":"NN"},{"id":"T14160","span":{"begin":142,"end":143},"obj":"-COMMA-"},{"id":"T14161","span":{"begin":144,"end":146},"obj":"PRP"},{"id":"T14162","span":{"begin":147,"end":150},"obj":"MD"},{"id":"T14163","span":{"begin":150,"end":153},"obj":"RB"},{"id":"T14164","span":{"begin":154,"end":161},"obj":"VB"},{"id":"T14165","span":{"begin":162,"end":166},"obj":"DT"},{"id":"T14166","span":{"begin":167,"end":171},"obj":"NN"},{"id":"T14167","span":{"begin":172,"end":175},"obj":"MD"},{"id":"T14168","span":{"begin":176,"end":180},"obj":"RB"},{"id":"T14169","span":{"begin":181,"end":188},"obj":"VB"},{"id":"T14170","span":{"begin":189,"end":194},"obj":"NN"},{"id":"T14171","span":{"begin":195,"end":205},"obj":"NN"},{"id":"T14172","span":{"begin":206,"end":208},"obj":"IN"},{"id":"T14173","span":{"begin":209,"end":214},"obj":"NN"},{"id":"T14174","span":{"begin":215,"end":220},"obj":"NN"},{"id":"T14175","span":{"begin":221,"end":223},"obj":"FW"},{"id":"T14176","span":{"begin":224,"end":228},"obj":"FW"},{"id":"T14177","span":{"begin":229,"end":231},"obj":"CC"},{"id":"T14178","span":{"begin":232,"end":236},"obj":"IN"},{"id":"T14179","span":{"begin":237,"end":247},"obj":"JJ"},{"id":"T14180","span":{"begin":248,"end":255},"obj":"NN"},{"id":"T14181","span":{"begin":256,"end":259},"obj":"MD"},{"id":"T14182","span":{"begin":260,"end":270},"obj":"VB"},{"id":"T14183","span":{"begin":271,"end":273},"obj":"TO"},{"id":"T14184","span":{"begin":274,"end":277},"obj":"DT"},{"id":"T14185","span":{"begin":278,"end":286},"obj":"VB"},{"id":"T14186","span":{"begin":287,"end":291},"obj":"NN"},{"id":"T14187","span":{"begin":292,"end":294},"obj":"IN"},{"id":"T14188","span":{"begin":295,"end":300},"obj":"NN"},{"id":"T14189","span":{"begin":301,"end":311},"obj":"NN"}],"relations":[{"id":"R10530","pred":"arg1Of","subj":"T14140","obj":"T14139"},{"id":"R10531","pred":"arg1Of","subj":"T14140","obj":"T14141"},{"id":"R10532","pred":"arg1Of","subj":"T14140","obj":"T14146"},{"id":"R10533","pred":"arg1Of","subj":"T14140","obj":"T14149"},{"id":"R10534","pred":"arg1Of","subj":"T14142","obj":"T14143"},{"id":"R10535","pred":"arg2Of","subj":"T14144","obj":"T14143"},{"id":"R10536","pred":"arg2Of","subj":"T14145","obj":"T14141"},{"id":"R10537","pred":"arg1Of","subj":"T14145","obj":"T14142"},{"id":"R10538","pred":"arg1Of","subj":"T14145","obj":"T14144"},{"id":"R10539","pred":"arg2Of","subj":"T14146","obj":"T14138"},{"id":"R10540","pred":"arg1Of","subj":"T14146","obj":"T14147"},{"id":"R10541","pred":"arg1Of","subj":"T14146","obj":"T14148"},{"id":"R10542","pred":"arg1Of","subj":"T14146","obj":"T14150"},{"id":"R10543","pred":"arg1Of","subj":"T14146","obj":"T14151"},{"id":"R10544","pred":"arg2Of","subj":"T14149","obj":"T14146"},{"id":"R10545","pred":"arg1Of","subj":"T14153","obj":"T14152"},{"id":"R10546","pred":"arg1Of","subj":"T14153","obj":"T14156"},{"id":"R10547","pred":"arg2Of","subj":"T14156","obj":"T14151"},{"id":"R10548","pred":"arg1Of","subj":"T14156","obj":"T14154"},{"id":"R10549","pred":"arg1Of","subj":"T14156","obj":"T14155"},{"id":"R10550","pred":"arg1Of","subj":"T14156","obj":"T14158"},{"id":"R10551","pred":"arg2Of","subj":"T14157","obj":"T14156"},{"id":"R10552","pred":"arg2Of","subj":"T14159","obj":"T14158"},{"id":"R10553","pred":"arg2Of","subj":"T14159","obj":"T14164"},{"id":"R10554","pred":"arg1Of","subj":"T14161","obj":"T14162"},{"id":"R10555","pred":"arg1Of","subj":"T14161","obj":"T14164"},{"id":"R10556","pred":"arg1Of","subj":"T14164","obj":"T14160"},{"id":"R10557","pred":"arg2Of","subj":"T14164","obj":"T14162"},{"id":"R10558","pred":"arg1Of","subj":"T14164","obj":"T14163"},{"id":"R10559","pred":"arg1Of","subj":"T14166","obj":"T14167"},{"id":"R10560","pred":"arg1Of","subj":"T14166","obj":"T14169"},{"id":"R10561","pred":"arg1Of","subj":"T14169","obj":"T14165"},{"id":"R10562","pred":"arg2Of","subj":"T14169","obj":"T14167"},{"id":"R10563","pred":"arg1Of","subj":"T14169","obj":"T14168"},{"id":"R10564","pred":"arg1Of","subj":"T14169","obj":"T14176"},{"id":"R10565","pred":"arg1Of","subj":"T14169","obj":"T14177"},{"id":"R10566","pred":"arg2Of","subj":"T14171","obj":"T14169"},{"id":"R10567","pred":"arg1Of","subj":"T14171","obj":"T14170"},{"id":"R10568","pred":"arg1Of","subj":"T14171","obj":"T14172"},{"id":"R10569","pred":"arg2Of","subj":"T14174","obj":"T14172"},{"id":"R10570","pred":"arg1Of","subj":"T14174","obj":"T14173"},{"id":"R10571","pred":"arg1Of","subj":"T14176","obj":"T14175"},{"id":"R10572","pred":"arg1Of","subj":"T14177","obj":"T14181"},{"id":"R10573","pred":"arg1Of","subj":"T14177","obj":"T14182"},{"id":"R10574","pred":"arg2Of","subj":"T14178","obj":"T14177"},{"id":"R10575","pred":"arg2Of","subj":"T14180","obj":"T14178"},{"id":"R10576","pred":"arg1Of","subj":"T14180","obj":"T14179"},{"id":"R10577","pred":"arg1Of","subj":"T14182","obj":"T14137"},{"id":"R10578","pred":"arg1Of","subj":"T14182","obj":"T14138"},{"id":"R10579","pred":"arg2Of","subj":"T14182","obj":"T14181"},{"id":"R10580","pred":"arg1Of","subj":"T14182","obj":"T14183"},{"id":"R10581","pred":"arg1Of","subj":"T14182","obj":"T14187"},{"id":"R10582","pred":"arg2Of","subj":"T14186","obj":"T14183"},{"id":"R10583","pred":"arg1Of","subj":"T14186","obj":"T14184"},{"id":"R10584","pred":"arg2Of","subj":"T14186","obj":"T14185"},{"id":"R10585","pred":"arg2Of","subj":"T14189","obj":"T14187"},{"id":"R10586","pred":"arg1Of","subj":"T14189","obj":"T14188"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    bionlp-st-ge-2016-spacy-parsed

    {"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T15603","span":{"begin":0,"end":3},"obj":"CC"},{"id":"T15604","span":{"begin":4,"end":9},"obj":"IN"},{"id":"T15605","span":{"begin":10,"end":11},"obj":"DT"},{"id":"T15606","span":{"begin":12,"end":23},"obj":"NN"},{"id":"T15607","span":{"begin":24,"end":26},"obj":"IN"},{"id":"T15608","span":{"begin":27,"end":32},"obj":"NNP"},{"id":"T15609","span":{"begin":33,"end":36},"obj":"CC"},{"id":"T15610","span":{"begin":37,"end":42},"obj":"NNP"},{"id":"T15611","span":{"begin":43,"end":48},"obj":"NNS"},{"id":"T15612","span":{"begin":49,"end":51},"obj":"VBZ"},{"id":"T15613","span":{"begin":52,"end":61},"obj":"RB"},{"id":"T15614","span":{"begin":62,"end":65},"obj":"RB"},{"id":"T15615","span":{"begin":66,"end":74},"obj":"JJ"},{"id":"T15616","span":{"begin":74,"end":75},"obj":","},{"id":"T15617","span":{"begin":76,"end":83},"obj":"IN"},{"id":"T15618","span":{"begin":84,"end":89},"obj":"NNP"},{"id":"T15619","span":{"begin":90,"end":95},"obj":"NNS"},{"id":"T15620","span":{"begin":96,"end":100},"obj":"RB"},{"id":"T15621","span":{"begin":101,"end":112},"obj":"RB"},{"id":"T15622","span":{"begin":113,"end":120},"obj":"JJ"},{"id":"T15623","span":{"begin":121,"end":125},"obj":"NNS"},{"id":"T15624","span":{"begin":126,"end":131},"obj":"IN"},{"id":"T15625","span":{"begin":132,"end":142},"obj":"NN"},{"id":"T15626","span":{"begin":142,"end":143},"obj":","},{"id":"T15627","span":{"begin":144,"end":146},"obj":"PRP"},{"id":"T15628","span":{"begin":147,"end":150},"obj":"MD"},{"id":"T15629","span":{"begin":150,"end":153},"obj":"RB"},{"id":"T15630","span":{"begin":154,"end":161},"obj":"VB"},{"id":"T15631","span":{"begin":162,"end":166},"obj":"DT"},{"id":"T15632","span":{"begin":167,"end":171},"obj":"NN"},{"id":"T15633","span":{"begin":172,"end":175},"obj":"MD"},{"id":"T15634","span":{"begin":176,"end":180},"obj":"RB"},{"id":"T15635","span":{"begin":181,"end":188},"obj":"VB"},{"id":"T15636","span":{"begin":189,"end":194},"obj":"JJ"},{"id":"T15637","span":{"begin":195,"end":205},"obj":"NN"},{"id":"T15638","span":{"begin":206,"end":208},"obj":"IN"},{"id":"T15639","span":{"begin":209,"end":214},"obj":"NNP"},{"id":"T15640","span":{"begin":215,"end":220},"obj":"NNS"},{"id":"T15641","span":{"begin":221,"end":223},"obj":"IN"},{"id":"T15642","span":{"begin":224,"end":228},"obj":"NN"},{"id":"T15643","span":{"begin":229,"end":231},"obj":"CC"},{"id":"T15644","span":{"begin":232,"end":236},"obj":"IN"},{"id":"T15645","span":{"begin":237,"end":247},"obj":"JJ"},{"id":"T15646","span":{"begin":248,"end":255},"obj":"NNS"},{"id":"T15647","span":{"begin":256,"end":259},"obj":"MD"},{"id":"T15648","span":{"begin":260,"end":270},"obj":"VB"},{"id":"T15649","span":{"begin":271,"end":273},"obj":"TO"},{"id":"T15650","span":{"begin":274,"end":277},"obj":"DT"},{"id":"T15651","span":{"begin":278,"end":286},"obj":"JJ"},{"id":"T15652","span":{"begin":287,"end":291},"obj":"NN"},{"id":"T15653","span":{"begin":292,"end":294},"obj":"IN"},{"id":"T15654","span":{"begin":295,"end":300},"obj":"JJ"},{"id":"T15655","span":{"begin":301,"end":311},"obj":"NN"},{"id":"T15656","span":{"begin":311,"end":312},"obj":"."}],"relations":[{"id":"R12053","pred":"cc","subj":"T15603","obj":"T15630"},{"id":"R12054","pred":"prep","subj":"T15604","obj":"T15630"},{"id":"R11791","pred":"det","subj":"T15605","obj":"T15606"},{"id":"R11793","pred":"pobj","subj":"T15606","obj":"T15604"},{"id":"R11795","pred":"prep","subj":"T15607","obj":"T15606"},{"id":"R11796","pred":"nmod","subj":"T15608","obj":"T15611"},{"id":"R11797","pred":"cc","subj":"T15609","obj":"T15608"},{"id":"R11799","pred":"conj","subj":"T15610","obj":"T15608"},{"id":"R11800","pred":"pobj","subj":"T15611","obj":"T15607"},{"id":"R11801","pred":"advcl","subj":"T15612","obj":"T15630"},{"id":"R11802","pred":"advmod","subj":"T15613","obj":"T15612"},{"id":"R11804","pred":"neg","subj":"T15614","obj":"T15612"},{"id":"R11806","pred":"acomp","subj":"T15615","obj":"T15612"},{"id":"R11807","pred":"punct","subj":"T15616","obj":"T15612"},{"id":"R11809","pred":"mark","subj":"T15617","obj":"T15622"},{"id":"R11810","pred":"compound","subj":"T15618","obj":"T15619"},{"id":"R11811","pred":"nsubj","subj":"T15619","obj":"T15622"},{"id":"R11813","pred":"advmod","subj":"T15620","obj":"T15621"},{"id":"R11814","pred":"advmod","subj":"T15621","obj":"T15622"},{"id":"R11815","pred":"advcl","subj":"T15622","obj":"T15630"},{"id":"R11816","pred":"dobj","subj":"T15623","obj":"T15622"},{"id":"R11817","pred":"prep","subj":"T15624","obj":"T15622"},{"id":"R11818","pred":"pobj","subj":"T15625","obj":"T15624"},{"id":"R11820","pred":"punct","subj":"T15626","obj":"T15630"},{"id":"R11821","pred":"nsubj","subj":"T15627","obj":"T15630"},{"id":"R11822","pred":"aux","subj":"T15628","obj":"T15630"},{"id":"R11824","pred":"neg","subj":"T15629","obj":"T15630"},{"id":"R11825","pred":"ROOT","subj":"T15630","obj":"T15630"},{"id":"R11826","pred":"mark","subj":"T15631","obj":"T15635"},{"id":"R11828","pred":"nsubj","subj":"T15632","obj":"T15635"},{"id":"R11829","pred":"aux","subj":"T15633","obj":"T15635"},{"id":"R11831","pred":"advmod","subj":"T15634","obj":"T15635"},{"id":"R11832","pred":"ccomp","subj":"T15635","obj":"T15630"},{"id":"R11833","pred":"amod","subj":"T15636","obj":"T15637"},{"id":"R11834","pred":"dobj","subj":"T15637","obj":"T15635"},{"id":"R11835","pred":"prep","subj":"T15638","obj":"T15635"},{"id":"R11837","pred":"compound","subj":"T15639","obj":"T15640"},{"id":"R11838","pred":"pobj","subj":"T15640","obj":"T15638"},{"id":"R11839","pred":"prep","subj":"T15641","obj":"T15640"},{"id":"R11841","pred":"pobj","subj":"T15642","obj":"T15641"},{"id":"R11842","pred":"cc","subj":"T15643","obj":"T15635"},{"id":"R11843","pred":"mark","subj":"T15644","obj":"T15648"},{"id":"R11844","pred":"amod","subj":"T15645","obj":"T15646"},{"id":"R11847","pred":"nsubj","subj":"T15646","obj":"T15648"},{"id":"R11848","pred":"aux","subj":"T15647","obj":"T15648"},{"id":"R11850","pred":"conj","subj":"T15648","obj":"T15635"},{"id":"R11851","pred":"prep","subj":"T15649","obj":"T15648"},{"id":"R11852","pred":"det","subj":"T15650","obj":"T15652"},{"id":"R11853","pred":"amod","subj":"T15651","obj":"T15652"},{"id":"R11855","pred":"pobj","subj":"T15652","obj":"T15649"},{"id":"R11858","pred":"prep","subj":"T15653","obj":"T15652"},{"id":"R11859","pred":"amod","subj":"T15654","obj":"T15655"},{"id":"R11861","pred":"pobj","subj":"T15655","obj":"T15653"},{"id":"R11862","pred":"punct","subj":"T15656","obj":"T15630"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T16693","span":{"begin":167,"end":171},"obj":"http://purl.obolibrary.org/obo/GO_0005136"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T16730","span":{"begin":43,"end":48},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T16731","span":{"begin":90,"end":95},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T16732","span":{"begin":215,"end":220},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    sentences

    {"project":"sentences","denotations":[{"id":"T13448","span":{"begin":0,"end":312},"obj":"Sentence"},{"id":"T225","span":{"begin":0,"end":312},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    events-check-again

    {"project":"events-check-again","denotations":[{"id":"T17410","span":{"begin":113,"end":120},"obj":"Gene_expression"},{"id":"T17411","span":{"begin":121,"end":125},"obj":"Protein"},{"id":"T17412","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T17413","span":{"begin":181,"end":188},"obj":"Negative_regulation"},{"id":"T17414","span":{"begin":189,"end":194},"obj":"Protein"},{"id":"T17415","span":{"begin":195,"end":205},"obj":"Gene_expression"},{"id":"T17416","span":{"begin":260,"end":270},"obj":"Positive_regulation"},{"id":"T17417","span":{"begin":287,"end":291},"obj":"Negative_regulation"},{"id":"T17418","span":{"begin":295,"end":300},"obj":"Protein"},{"id":"T17419","span":{"begin":301,"end":311},"obj":"Gene_expression"}],"relations":[{"id":"R13215","pred":"causeOf","subj":"T17410","obj":"T17413"},{"id":"R13216","pred":"themeOf","subj":"T17411","obj":"T17410"},{"id":"R13217","pred":"themeOf","subj":"T17414","obj":"T17415"},{"id":"R13219","pred":"themeOf","subj":"T17415","obj":"T17413"},{"id":"R13220","pred":"themeOf","subj":"T17417","obj":"T17416"},{"id":"R13222","pred":"themeOf","subj":"T17418","obj":"T17419"},{"id":"R13223","pred":"themeOf","subj":"T17419","obj":"T17417"}],"attributes":[{"id":"M413","pred":"Speculation","subj":"T17416","obj":"true"},{"id":"M412","pred":"Speculation","subj":"T17413","obj":"true"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    bionlp-st-ge-2016-reference

    {"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T13522","span":{"begin":113,"end":120},"obj":"Gene_expression"},{"id":"T13523","span":{"begin":181,"end":188},"obj":"Negative_regulation"},{"id":"T13524","span":{"begin":195,"end":205},"obj":"Gene_expression"},{"id":"T13525","span":{"begin":260,"end":270},"obj":"Positive_regulation"},{"id":"T13526","span":{"begin":287,"end":291},"obj":"Negative_regulation"},{"id":"T13527","span":{"begin":301,"end":311},"obj":"Gene_expression"},{"id":"T13640","span":{"begin":121,"end":125},"obj":"Protein"},{"id":"T13641","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T13642","span":{"begin":189,"end":194},"obj":"Protein"},{"id":"T13643","span":{"begin":295,"end":300},"obj":"Protein"}],"relations":[{"id":"R9966","pred":"causeOf","subj":"T13522","obj":"T13523"},{"id":"R9967","pred":"themeOf","subj":"T13524","obj":"T13523"},{"id":"R9968","pred":"themeOf","subj":"T13526","obj":"T13525"},{"id":"R9969","pred":"themeOf","subj":"T13527","obj":"T13526"},{"id":"R10044","pred":"themeOf","subj":"T13640","obj":"T13522"},{"id":"R10045","pred":"themeOf","subj":"T13642","obj":"T13524"},{"id":"R10046","pred":"themeOf","subj":"T13643","obj":"T13527"}],"attributes":[{"id":"M363","pred":"Speculation","subj":"T13523","obj":"true"},{"id":"M364","pred":"Speculation","subj":"T13525","obj":"true"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T15018","span":{"begin":121,"end":125},"obj":"P01589"},{"id":"T15019","span":{"begin":167,"end":171},"obj":"P05112"},{"id":"T15020","span":{"begin":189,"end":194},"obj":"Q9BZS1"},{"id":"T15021","span":{"begin":295,"end":300},"obj":"Q9BZS1"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}

    test2

    {"project":"test2","denotations":[{"id":"T13289","span":{"begin":113,"end":120},"obj":"Gene_expression"},{"id":"T13290","span":{"begin":121,"end":125},"obj":"Protein"},{"id":"T13291","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T13292","span":{"begin":181,"end":188},"obj":"Negative_regulation"},{"id":"T13293","span":{"begin":189,"end":194},"obj":"Protein"},{"id":"T13294","span":{"begin":195,"end":205},"obj":"Gene_expression"},{"id":"T13295","span":{"begin":260,"end":270},"obj":"Positive_regulation"},{"id":"T13296","span":{"begin":287,"end":291},"obj":"Negative_regulation"},{"id":"T13297","span":{"begin":295,"end":300},"obj":"Protein"},{"id":"T13298","span":{"begin":301,"end":311},"obj":"Gene_expression"}],"relations":[{"id":"R9886","pred":"causeOf","subj":"T13289","obj":"T13292"},{"id":"R9887","pred":"themeOf","subj":"T13290","obj":"T13289"},{"id":"R9888","pred":"causeOf","subj":"T13291","obj":"T13292"},{"id":"R9889","pred":"themeOf","subj":"T13293","obj":"T13294"},{"id":"R9890","pred":"themeOf","subj":"T13294","obj":"T13292"},{"id":"R9891","pred":"themeOf","subj":"T13297","obj":"T13298"},{"id":"R9892","pred":"themeOf","subj":"T13298","obj":"T13296"}],"attributes":[{"id":"M357","pred":"Negation","subj":"T13295","obj":"true"}],"text":"But since a distinction of nTreg and iTreg cells is currently not possible, because iTreg cells also transiently express CD25 after activation, we cannot exclude that IL-4 may also inhibit Foxp3 expression in nTreg cells in vivo or that additional effects may contribute to the observed drop in Foxp3 expression."}