PMC:2222968 / 23457-27615 JSON TXT

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2_test

Id	Subject	Object	Predicate	Lexical cue
18162042-16517728-84705024	303-305	16517728	denotes	24
18162042-16517728-84705025	527-529	16517728	denotes	24
18162042-8083467-84705026	684-686	8083467	denotes	25
18162042-7654359-84705027	687-689	7654359	denotes	26
T17011	303-305	16517728	denotes	24
T99449	527-529	16517728	denotes	24
T74593	684-686	8083467	denotes	25
T43549	687-689	7654359	denotes	26

pmc-enju-pas

Id	Subject	Object	Predicate	Lexical cue
T11599	0-5	NN	denotes	GATA3
T11600	6-15	VB	denotes	Represses
T11601	16-19	DT	denotes	the
T11602	20-25	NN	denotes	FOXP3
T11603	26-34	NN	denotes	Promoter
T11604	35-37	TO	denotes	To
T11605	38-49	VB	denotes	investigate
T11606	50-53	DT	denotes	the
T11607	54-63	JJ	denotes	molecular
T11608	64-73	NN	denotes	mechanism
T11609	74-76	IN	denotes	of
T11610	77-91	JJ	denotes	GATA3-mediated
T11611	92-102	NN	denotes	repression
T11612	103-105	IN	denotes	of
T11613	106-111	JJ	denotes	human
T11614	112-117	NN	denotes	FOXP3
T11615	117-118	-COMMA-	denotes	,
T11616	119-122	DT	denotes	the
T11617	123-128	JJ	denotes	human
T11618	129-134	NN	denotes	FOXP3
T11619	135-143	NN	denotes	promoter
T11620	144-147	VB	denotes	was
T11621	148-155	VB	denotes	studied
T11622	156-159	CC	denotes	and
T11623	160-161	DT	denotes	a
T11624	162-173	JJ	denotes	palindromic
T11625	174-181	NN	denotes	binding
T11626	182-186	NN	denotes	site
T11627	187-190	IN	denotes	for
T11628	191-196	NN	denotes	GATA3
T11629	197-200	VB	denotes	was
T11630	201-211	VB	denotes	discovered
T11631	213-216	DT	denotes	The
T11632	217-229	JJ	denotes	GATA-binding
T11633	230-234	NN	denotes	site
T11634	235-237	VB	denotes	is
T11635	238-245	JJ	denotes	located
T11636	246-249	CD	denotes	303
T11637	250-252	NN	denotes	bp
T11638	253-261	RB	denotes	upstream
T11639	262-266	IN	denotes	from
T11640	267-270	DT	denotes	the
T11641	271-284	NN	denotes	transcription
T11642	285-290	NN	denotes	start
T11643	291-295	NN	denotes	site
T11644	296-297	-LRB-	denotes	(
T11645	297-300	NN	denotes	TSS
T11646	300-301	-RRB-	denotes	)
T11647	302-303	-LRB-	denotes	[
T11648	303-305	CD	denotes	24
T11649	305-306	-RRB-	denotes	]
T11650	308-312	DT	denotes	This
T11651	313-317	NN	denotes	site
T11652	318-320	VB	denotes	is
T11653	321-327	RB	denotes	highly
T11654	328-337	VB	denotes	conserved
T11655	338-345	IN	denotes	between
T11656	346-352	NN	denotes	humans
T11657	352-353	-COMMA-	denotes	,
T11658	354-358	NN	denotes	mice
T11659	358-359	-COMMA-	denotes	,
T11660	360-363	CC	denotes	and
T11661	364-368	NN	denotes	rats
T11662	369-370	-LRB-	denotes	(
T11663	370-376	NN	denotes	Figure
T11664	377-379	NN	denotes	S4
T11665	379-380	-RRB-	denotes	)
T11666	381-384	CC	denotes	and
T11667	385-388	MD	denotes	may
T11668	389-398	RB	denotes	therefore
T11669	399-403	VB	denotes	play
T11670	404-406	DT	denotes	an
T11671	407-416	JJ	denotes	important
T11672	417-421	NN	denotes	role
T11673	422-424	IN	denotes	in
T11674	425-430	NN	denotes	FOXP3
T11675	431-441	NN	denotes	regulation
T11676	443-446	DT	denotes	The
T11677	447-457	JJ	denotes	functional
T11678	458-467	NN	denotes	relevance
T11679	468-470	IN	denotes	of
T11680	471-475	DT	denotes	this
T11681	476-480	NN	denotes	site
T11682	481-484	VB	denotes	was
T11683	485-492	VB	denotes	studied
T11684	493-498	VB	denotes	using
T11685	499-500	DT	denotes	a
T11686	501-515	NN	denotes	FOXP3-promoter
T11687	516-525	NN	denotes	construct
T11688	526-527	-LRB-	denotes	[
T11689	527-529	CD	denotes	24
T11690	529-530	-RRB-	denotes	]
T11691	532-534	PRP	denotes	We
T11692	535-546	VB	denotes	transfected
T11693	547-552	JJ	denotes	human
T11694	553-560	JJ	denotes	primary
T11695	561-565	JJ	denotes	CD4+
T11696	566-567	NN	denotes	T
T11697	568-573	NN	denotes	cells
T11698	573-574	-COMMA-	denotes	,
T11699	575-577	FW	denotes	in
T11700	578-583	FW	denotes	vitro
T11701	584-598	VB	denotes	differentiated
T11702	599-602	NN	denotes	Th2
T11703	603-608	NN	denotes	cells
T11704	608-609	-COMMA-	denotes	,
T11705	610-613	CC	denotes	and
T11706	614-620	NN	denotes	Jurkat
T11707	621-626	NN	denotes	cells
T11708	627-628	-LRB-	denotes	(
T11709	628-634	NN	denotes	Jurkat
T11710	635-640	NN	denotes	cells
T11711	641-644	VB	denotes	are
T11712	645-650	VB	denotes	known
T11713	651-653	TO	denotes	to
T11714	654-668	RB	denotes	constitutively
T11715	669-676	VB	denotes	express
T11716	677-682	NN	denotes	GATA3
T11717	683-684	-LRB-	denotes	[
T11718	684-689	CD	denotes	25,26
T11719	689-690	-RRB-	denotes	]
T11720	690-691	-RRB-	denotes	)
T11721	691-692	-COMMA-	denotes	,
T11722	693-696	CC	denotes	and
T11723	697-699	PRP	denotes	we
T11724	700-708	VB	denotes	measured
T11725	709-714	NN	denotes	FOXP3
T11726	715-723	NN	denotes	promoter
T11727	724-732	NN	denotes	activity
T11728	734-737	DT	denotes	The
T11729	738-746	NN	denotes	promoter
T11730	747-750	VB	denotes	was
T11731	751-754	RB	denotes	not
T11732	755-761	JJ	denotes	active
T11733	762-764	IN	denotes	in
T11734	765-768	DT	denotes	the
T11735	769-785	JJ	denotes	GATA3-expressing
T11736	786-790	NN	denotes	cell
T11737	791-795	NN	denotes	line
T11738	796-802	NN	denotes	Jurkat
T11739	803-805	CC	denotes	or
T11740	806-808	IN	denotes	in
T11741	809-812	DT	denotes	the
T11742	813-815	IN	denotes	in
T11743	816-836	JJ	denotes	vitro-differentiated
T11744	837-840	NN	denotes	Th2
T11745	841-846	NN	denotes	cells
T11746	846-847	-COMMA-	denotes	,
T11747	848-855	IN	denotes	whereas
T11748	856-859	DT	denotes	the
T11749	860-869	NN	denotes	construct
T11750	870-873	VB	denotes	was
T11751	874-880	JJ	denotes	active
T11752	881-883	IN	denotes	in
T11753	884-887	DT	denotes	the
T11754	888-891	NN	denotes	CD4
T11755	892-897	NN	denotes	cells
T11756	897-898	-COMMA-	denotes	,
T11757	899-904	WDT	denotes	which
T11758	905-912	VB	denotes	express
T11759	913-914	DT	denotes	a
T11760	915-920	JJ	denotes	lower
T11761	921-927	NN	denotes	amount
T11762	928-930	IN	denotes	of
T11763	931-936	NN	denotes	GATA3
T11764	937-938	-LRB-	denotes	(
T11765	938-944	NN	denotes	Figure
T11766	945-947	NN	denotes	8A
T11767	947-948	-RRB-	denotes	)
T11768	950-964	NN	denotes	Overexpression
T11769	965-967	IN	denotes	of
T11770	968-973	NN	denotes	GATA3
T11771	974-976	IN	denotes	in
T11772	977-982	JJ	denotes	naive
T11773	983-984	NN	denotes	T
T11774	985-990	NN	denotes	cells
T11775	991-1001	VB	denotes	diminished
T11776	1002-1012	NN	denotes	luciferase
T11777	1013-1021	NN	denotes	activity
T11778	1022-1024	IN	denotes	of
T11779	1025-1028	DT	denotes	the
T11780	1029-1034	NN	denotes	FOXP3
T11781	1035-1043	NN	denotes	promoter
T11782	1044-1052	VB	denotes	compared
T11783	1053-1057	IN	denotes	with
T11784	1058-1061	DT	denotes	the
T11785	1062-1069	NN	denotes	control
T11786	1070-1076	NN	denotes	vector
T11787	1077-1078	-LRB-	denotes	(
T11788	1078-1084	NN	denotes	Figure
T11789	1085-1087	NN	denotes	8B
T11790	1087-1088	-RRB-	denotes	)
T11791	1090-1092	TO	denotes	To
T11792	1093-1100	RB	denotes	further
T11793	1101-1108	VB	denotes	address
T11794	1109-1112	DT	denotes	the
T11795	1113-1121	NN	denotes	function
T11796	1122-1124	IN	denotes	of
T11797	1125-1128	DT	denotes	the
T11798	1129-1134	NN	denotes	GATA3
T11799	1135-1139	NN	denotes	site
T11800	1139-1140	-COMMA-	denotes	,
T11801	1141-1143	PRP	denotes	we
T11802	1144-1152	VB	denotes	inserted
T11803	1153-1154	DT	denotes	a
T11804	1155-1168	JJ	denotes	site-specific
T11805	1169-1177	NN	denotes	mutation
T11806	1178-1186	VB	denotes	deleting
T11807	1187-1190	DT	denotes	the
T11808	1191-1204	JJ	denotes	GATA3-binding
T11809	1205-1209	NN	denotes	site
T11810	1211-1215	DT	denotes	This
T11811	1216-1224	NN	denotes	mutation
T11812	1225-1234	VB	denotes	increased
T11813	1235-1245	NN	denotes	luciferase
T11814	1246-1254	NN	denotes	activity
T11815	1255-1257	IN	denotes	by
T11816	1258-1264	RB	denotes	3-fold
T11817	1265-1267	IN	denotes	in
T11818	1268-1274	NN	denotes	memory
T11819	1275-1286	JJ	denotes	CD4+CD45RO+
T11820	1287-1288	NN	denotes	T
T11821	1289-1294	NN	denotes	cells
T11822	1294-1295	-COMMA-	denotes	,
T11823	1296-1303	IN	denotes	whereas
T11824	1304-1306	DT	denotes	no
T11825	1307-1317	NN	denotes	difference
T11826	1318-1321	VB	denotes	was
T11827	1322-1330	VB	denotes	observed
T11828	1331-1333	IN	denotes	in
T11829	1334-1339	JJ	denotes	naive
T11830	1340-1341	-LRB-	denotes	(
T11831	1341-1347	NN	denotes	GATA3–
T11832	1347-1348	-RRB-	denotes	)
T11833	1349-1360	JJ	denotes	CD4+CD45RA+
T11834	1361-1362	NN	denotes	T
T11835	1363-1368	NN	denotes	cells
T11836	1368-1369	-COMMA-	denotes	,
T11837	1370-1379	VB	denotes	revealing
T11838	1380-1381	DT	denotes	a
T11839	1382-1391	NN	denotes	repressor
T11840	1392-1400	NN	denotes	activity
T11841	1401-1403	IN	denotes	of
T11842	1404-1409	NN	denotes	GATA3
T11843	1410-1412	IN	denotes	on
T11844	1413-1416	DT	denotes	the
T11845	1417-1422	NN	denotes	FOXP3
T11846	1423-1431	NN	denotes	promoter
T11847	1432-1433	-LRB-	denotes	(
T11848	1433-1439	NN	denotes	Figure
T11849	1440-1442	NN	denotes	8C
T11850	1442-1443	-RRB-	denotes	)
T11851	1445-1456	RB	denotes	Furthermore
T11852	1457-1462	NN	denotes	GATA3
T11853	1463-1468	VB	denotes	binds
T11854	1469-1477	RB	denotes	directly
T11855	1478-1480	TO	denotes	to
T11856	1481-1484	DT	denotes	the
T11857	1485-1490	NN	denotes	FOXP3
T11858	1491-1499	NN	denotes	promoter
T11859	1500-1502	IN	denotes	as
T11860	1503-1515	VB	denotes	investigated
T11861	1516-1518	IN	denotes	by
T11862	1519-1528	JJ	denotes	pull-down
T11863	1529-1534	NN	denotes	assay
T11864	1536-1539	NN	denotes	HEK
T11865	1540-1545	NN	denotes	cells
T11866	1546-1550	VB	denotes	were
T11867	1551-1562	RB	denotes	transiently
T11868	1563-1574	VB	denotes	transfected
T11869	1575-1579	IN	denotes	with
T11870	1580-1585	NN	denotes	GATA3
T11871	1586-1588	CC	denotes	or
T11872	1589-1590	DT	denotes	a
T11873	1591-1598	NN	denotes	control
T11874	1599-1605	NN	denotes	vector
T11875	1605-1606	-COMMA-	denotes	,
T11876	1607-1610	CC	denotes	and
T11877	1611-1621	VB	denotes	increasing
T11878	1622-1629	NN	denotes	amounts
T11879	1630-1632	IN	denotes	of
T11880	1633-1640	NN	denotes	lysates
T11881	1641-1645	VB	denotes	were
T11882	1646-1655	VB	denotes	incubated
T11883	1656-1660	IN	denotes	with
T11884	1661-1677	NN	denotes	oligonucleotides
T11885	1678-1688	VB	denotes	containing
T11886	1689-1692	DT	denotes	the
T11887	1693-1698	NN	denotes	GATA3
T11888	1699-1703	NN	denotes	site
T11889	1704-1706	IN	denotes	of
T11890	1707-1710	DT	denotes	the
T11891	1711-1716	NN	denotes	FOXP3
T11892	1717-1725	NN	denotes	promoter
T11893	1726-1728	CC	denotes	or
T11894	1729-1730	DT	denotes	a
T11895	1731-1738	NN	denotes	control
T11896	1739-1754	NN	denotes	oligonucleotide
T11897	1755-1759	IN	denotes	with
T11898	1760-1761	DT	denotes	a
T11899	1762-1769	VB	denotes	mutated
T11900	1770-1783	JJ	denotes	GATA3-binding
T11901	1784-1788	NN	denotes	site
T11902	1790-1795	IN	denotes	After
T11903	1796-1799	DT	denotes	the
T11904	1800-1809	NN	denotes	pull-down
T11905	1809-1810	-COMMA-	denotes	,
T11906	1811-1816	NN	denotes	GATA3
T11907	1817-1824	NN	denotes	binding
T11908	1825-1828	VB	denotes	was
T11909	1829-1837	VB	denotes	detected
T11910	1838-1840	IN	denotes	by
T11911	1841-1848	JJ	denotes	Western
T11912	1849-1853	NN	denotes	blot
T11913	1855-1864	RB	denotes	Similarly
T11914	1864-1865	-COMMA-	denotes	,
T11915	1866-1882	JJ	denotes	GATA3-expressing
T11916	1883-1886	NN	denotes	Th2
T11917	1887-1892	NN	denotes	cells
T11918	1893-1896	CC	denotes	and
T11919	1897-1902	NN	denotes	iTreg
T11920	1903-1908	NN	denotes	cells
T11921	1909-1913	VB	denotes	were
T11922	1914-1923	VB	denotes	subjected
T11923	1924-1926	TO	denotes	to
T11924	1927-1931	DT	denotes	this
T11925	1932-1940	NN	denotes	approach
T11926	1942-1946	RB	denotes	Only
T11927	1947-1950	NN	denotes	HEK
T11928	1951-1956	NN	denotes	cells
T11929	1957-1971	VB	denotes	overexpressing
T11930	1972-1977	NN	denotes	GATA3
T11931	1978-1981	CC	denotes	and
T11932	1982-1985	NN	denotes	Th2
T11933	1986-1991	NN	denotes	cells
T11934	1992-1998	VB	denotes	showed
T11935	1999-2012	JJ	denotes	GATA3-binding
T11936	2013-2021	NN	denotes	activity
T11937	2022-2023	-LRB-	denotes	(
T11938	2023-2029	NN	denotes	Figure
T11939	2030-2032	NN	denotes	8D
T11940	2033-2036	CC	denotes	and
T11941	2037-2039	NN	denotes	8E
T11942	2039-2040	-RRB-	denotes	)
T11943	2042-2047	DT	denotes	These
T11944	2048-2059	NN	denotes	experiments
T11945	2060-2072	VB	denotes	demonstrated
T11946	2073-2077	IN	denotes	that
T11947	2078-2083	NN	denotes	GATA3
T11948	2084-2089	VB	denotes	binds
T11949	2090-2093	DT	denotes	the
T11950	2094-2105	JJ	denotes	palindromic
T11951	2106-2111	NN	denotes	FOXP3
T11952	2112-2120	NN	denotes	promoter
T11953	2122-2124	TO	denotes	To
T11954	2125-2129	VB	denotes	gain
T11955	2130-2138	NN	denotes	insights
T11956	2139-2143	IN	denotes	into
T11957	2144-2147	DT	denotes	the
T11958	2148-2150	FW	denotes	in
T11959	2151-2155	FW	denotes	vivo
T11960	2156-2165	NN	denotes	situation
T11961	2165-2166	-COMMA-	denotes	,
T11962	2167-2169	PRP	denotes	we
T11963	2170-2179	VB	denotes	performed
T11964	2180-2181	DT	denotes	a
T11965	2182-2191	NN	denotes	chromatin
T11966	2192-2211	NN	denotes	immunoprecipitation
T11967	2212-2213	-LRB-	denotes	(
T11968	2213-2217	NN	denotes	ChIP
T11969	2217-2218	-RRB-	denotes	)
T11970	2219-2224	VB	denotes	using
T11971	2225-2227	DT	denotes	an
T11972	2228-2238	JJ	denotes	anti-GATA3
T11973	2239-2247	NN	denotes	antibody
T11974	2248-2251	CC	denotes	and
T11975	2252-2258	VB	denotes	showed
T11976	2259-2263	IN	denotes	that
T11977	2264-2269	NN	denotes	GATA3
T11978	2270-2275	VB	denotes	binds
T11979	2276-2278	TO	denotes	to
T11980	2279-2282	DT	denotes	the
T11981	2283-2288	NN	denotes	FOXP3
T11982	2289-2297	NN	denotes	promoter
T11983	2298-2304	NN	denotes	region
T11984	2305-2307	IN	denotes	in
T11985	2308-2311	NN	denotes	Th2
T11986	2312-2317	NN	denotes	cells
T11987	2317-2318	-COMMA-	denotes	,
T11988	2319-2322	CC	denotes	but
T11989	2323-2326	RB	denotes	not
T11990	2327-2329	IN	denotes	in
T11991	2330-2335	NN	denotes	iTreg
T11992	2336-2341	NN	denotes	cells
T11993	2342-2343	-LRB-	denotes	(
T11994	2343-2349	NN	denotes	Figure
T11995	2350-2352	NN	denotes	7F
T11996	2352-2353	-RRB-	denotes	)
T11997	2355-2360	VB	denotes	Taken
T11998	2361-2369	RB	denotes	together
T11999	2370-2375	DT	denotes	these
T12000	2376-2380	NN	denotes	data
T12001	2381-2392	VB	denotes	demonstrate
T12002	2393-2397	IN	denotes	that
T12003	2398-2401	DT	denotes	the
T12004	2402-2415	NN	denotes	GATA3-binding
T12005	2416-2418	TO	denotes	to
T12006	2419-2422	DT	denotes	the
T12007	2423-2428	NN	denotes	FOXP3
T12008	2429-2437	NN	denotes	promoter
T12009	2438-2440	VB	denotes	is
T12010	2441-2451	VB	denotes	repressing
T12011	2452-2457	NN	denotes	FOXP3
T12012	2458-2468	NN	denotes	expression
T26944	2480-2485	NN	denotes	GATA3
T26945	2486-2495	VB	denotes	Represses
T26946	2496-2499	DT	denotes	the
T26947	2500-2505	JJ	denotes	Human
T26948	2506-2511	NN	denotes	FOXP3
T26949	2512-2520	NN	denotes	Promoter
T26950	2521-2522	-LRB-	denotes	(
T26951	2522-2523	NN	denotes	A
T26952	2523-2524	-RRB-	denotes	)
T26953	2525-2531	NN	denotes	Jurkat
T26954	2531-2532	-COMMA-	denotes	,
T26955	2533-2536	NN	denotes	Th2
T26956	2537-2542	NN	denotes	cells
T26957	2542-2543	-COMMA-	denotes	,
T26958	2544-2547	CC	denotes	and
T26959	2548-2553	JJ	denotes	human
T26960	2554-2561	JJ	denotes	primary
T26961	2562-2565	NN	denotes	CD4
T26962	2566-2571	NN	denotes	cells
T26963	2572-2576	VB	denotes	were
T26964	2577-2588	VB	denotes	transfected
T26965	2589-2593	IN	denotes	with
T26966	2594-2596	DT	denotes	an
T26967	2597-2602	JJ	denotes	empty
T26968	2603-2609	NN	denotes	vector
T26969	2610-2611	-LRB-	denotes	(
T26970	2611-2615	NN	denotes	pGL3
T26971	2616-2621	JJ	denotes	basic
T26972	2621-2622	-RRB-	denotes	)
T26973	2623-2625	CC	denotes	or
T26974	2626-2627	DT	denotes	a
T26975	2628-2634	NN	denotes	vector
T26976	2635-2645	VB	denotes	containing
T26977	2646-2649	DT	denotes	the
T26978	2650-2658	JJ	denotes	putative
T26979	2659-2664	NN	denotes	FOXP3
T26980	2665-2673	NN	denotes	promoter
T26981	2674-2680	NN	denotes	region
T26982	2681-2686	VB	denotes	fused
T26983	2687-2689	TO	denotes	to
T26984	2690-2693	DT	denotes	the
T26985	2694-2704	NN	denotes	luciferase
T26986	2705-2713	NN	denotes	reporter
T26987	2714-2718	NN	denotes	gene
T26988	2720-2724	NN	denotes	Bars
T26989	2725-2729	VB	denotes	show
T26990	2730-2733	DT	denotes	the
T26991	2734-2738	JJ	denotes	mean
T26992	2739-2740	JJ	denotes	±
T26993	2741-2743	NN	denotes	SD
T26994	2744-2746	IN	denotes	of
T26995	2747-2756	JJ	denotes	arbitrary
T26996	2757-2762	JJ	denotes	light
T26997	2763-2768	NN	denotes	units
T26998	2769-2779	VB	denotes	normalized
T26999	2780-2783	IN	denotes	for
T27000	2784-2791	NN	denotes	renilla
T27001	2792-2802	NN	denotes	luciferase
T27002	2803-2805	IN	denotes	of
T27003	2806-2810	CD	denotes	four
T27004	2811-2822	JJ	denotes	independent
T27005	2823-2834	NN	denotes	experiments
T27006	2834-2835	-COLON-	denotes	;
T27007	2836-2843	NN	denotes	samples
T27008	2844-2848	VB	denotes	were
T27009	2849-2857	VB	denotes	measured
T27010	2858-2860	IN	denotes	in
T27011	2861-2872	NN	denotes	triplicates
T27012	2874-2875	-LRB-	denotes	(
T27013	2875-2876	NN	denotes	B
T27014	2876-2877	-RRB-	denotes	)
T27015	2878-2883	JJ	denotes	Naive
T27016	2884-2887	NN	denotes	CD4
T27017	2888-2889	NN	denotes	T
T27018	2890-2895	NN	denotes	cells
T27019	2896-2900	VB	denotes	were
T27020	2901-2912	VB	denotes	transfected
T27021	2913-2917	IN	denotes	with
T27022	2918-2921	DT	denotes	the
T27023	2922-2927	NN	denotes	FOXP3
T27024	2928-2936	NN	denotes	promoter
T27025	2937-2945	NN	denotes	reporter
T27026	2946-2955	NN	denotes	construct
T27027	2956-2964	RB	denotes	together
T27028	2965-2969	IN	denotes	with
T27029	2970-2971	DT	denotes	a
T27030	2972-2977	NN	denotes	GATA3
T27031	2978-2988	NN	denotes	expression
T27032	2989-2995	NN	denotes	vector
T27033	2996-2998	CC	denotes	or
T27034	2999-3001	DT	denotes	an
T27035	3002-3007	JJ	denotes	empty
T27036	3008-3014	NN	denotes	vector
T27037	3016-3020	NN	denotes	Bars
T27038	3021-3025	VB	denotes	show
T27039	3026-3029	DT	denotes	the
T27040	3030-3034	JJ	denotes	mean
T27041	3035-3036	JJ	denotes	±
T27042	3037-3039	NN	denotes	SD
T27043	3040-3042	IN	denotes	of
T27044	3043-3048	CD	denotes	three
T27045	3049-3060	JJ	denotes	independent
T27046	3061-3072	NN	denotes	experiments
T27047	3074-3075	-LRB-	denotes	(
T27048	3075-3076	NN	denotes	C
T27049	3076-3077	-RRB-	denotes	)
T27050	3078-3083	JJ	denotes	Naive
T27051	3084-3085	-LRB-	denotes	(
T27052	3085-3089	JJ	denotes	left
T27053	3090-3095	NN	denotes	panel
T27054	3095-3096	-RRB-	denotes	)
T27055	3097-3099	CC	denotes	or
T27056	3100-3106	NN	denotes	memory
T27057	3107-3108	-LRB-	denotes	(
T27058	3108-3113	JJ	denotes	right
T27059	3114-3119	NN	denotes	panel
T27060	3119-3120	-RRB-	denotes	)
T27061	3121-3124	NN	denotes	CD4
T27062	3125-3126	NN	denotes	T
T27063	3127-3132	NN	denotes	cells
T27064	3133-3137	VB	denotes	were
T27065	3138-3149	VB	denotes	transfected
T27066	3150-3154	IN	denotes	with
T27067	3155-3164	JJ	denotes	wild-type
T27068	3165-3167	CC	denotes	or
T27069	3168-3169	DT	denotes	a
T27070	3170-3175	NN	denotes	GATA3
T27071	3176-3183	VB	denotes	mutated
T27072	3184-3193	NN	denotes	511-FOXP3
T27073	3194-3202	NN	denotes	promoter
T27074	3203-3211	NN	denotes	reporter
T27075	3212-3221	NN	denotes	construct
T27076	3222-3225	CC	denotes	and
T27077	3226-3235	VB	denotes	activated
T27078	3236-3240	IN	denotes	with
T27079	3241-3244	NN	denotes	PMA
T27080	3245-3248	CC	denotes	and
T27081	3249-3258	NN	denotes	ionomycin
T27082	3260-3264	NN	denotes	Bars
T27083	3265-3269	VB	denotes	show
T27084	3270-3273	DT	denotes	the
T27085	3274-3278	JJ	denotes	mean
T27086	3279-3280	JJ	denotes	±
T27087	3281-3283	NN	denotes	SD
T27088	3284-3286	IN	denotes	of
T27089	3287-3296	JJ	denotes	arbitrary
T27090	3297-3302	JJ	denotes	light
T27091	3303-3308	NN	denotes	units
T27092	3309-3319	VB	denotes	normalized
T27093	3320-3323	IN	denotes	for
T27094	3324-3331	NN	denotes	renilla
T27095	3332-3342	NN	denotes	luciferase
T27096	3343-3345	IN	denotes	of
T27097	3346-3351	CD	denotes	eight
T27098	3352-3363	JJ	denotes	independent
T27099	3364-3375	NN	denotes	experiments
T27100	3375-3376	-COLON-	denotes	;
T27101	3377-3384	NN	denotes	samples
T27102	3385-3389	VB	denotes	were
T27103	3390-3398	VB	denotes	measured
T27104	3399-3401	IN	denotes	in
T27105	3402-3413	NN	denotes	triplicates
T27106	3415-3416	-LRB-	denotes	(
T27107	3416-3417	NN	denotes	D
T27108	3417-3418	-RRB-	denotes	)
T27109	3419-3426	JJ	denotes	Nuclear
T27110	3427-3435	NN	denotes	extracts
T27111	3436-3440	VB	denotes	were
T27112	3441-3449	VB	denotes	prepared
T27113	3450-3454	IN	denotes	from
T27114	3455-3458	NN	denotes	HEK
T27115	3459-3464	NN	denotes	cells
T27116	3465-3476	VB	denotes	transfected
T27117	3477-3481	IN	denotes	with
T27118	3482-3487	NN	denotes	GATA3
T27119	3488-3490	CC	denotes	or
T27120	3491-3493	DT	denotes	an
T27121	3494-3499	JJ	denotes	empty
T27122	3500-3506	NN	denotes	vector
T27123	3506-3507	-COMMA-	denotes	,
T27124	3508-3509	-LRB-	denotes	(
T27125	3509-3510	NN	denotes	E
T27126	3510-3511	-RRB-	denotes	)
T27127	3512-3515	NN	denotes	Th1
T27128	3515-3516	-COMMA-	denotes	,
T27129	3517-3520	NN	denotes	Th2
T27130	3520-3521	-COMMA-	denotes	,
T27131	3522-3524	CC	denotes	or
T27132	3525-3530	NN	denotes	iTreg
T27133	3531-3536	NN	denotes	cells
T27134	3537-3540	CC	denotes	and
T27135	3541-3548	NN	denotes	binding
T27136	3549-3556	NN	denotes	factors
T27137	3557-3569	VB	denotes	precipitated
T27138	3570-3575	VB	denotes	using
T27139	3576-3588	VB	denotes	biotinylated
T27140	3589-3605	NN	denotes	oligonucleotides
T27141	3607-3610	DT	denotes	The
T27142	3611-3641	NN	denotes	oligonucleotides–transcription
T27143	3642-3648	NN	denotes	factor
T27144	3649-3658	NN	denotes	complexes
T27145	3659-3663	VB	denotes	were
T27146	3664-3673	VB	denotes	separated
T27147	3674-3676	IN	denotes	on
T27148	3677-3678	DT	denotes	a
T27149	3679-3687	NN	denotes	SDS-PAGE
T27150	3688-3691	NN	denotes	gel
T27151	3693-3696	DT	denotes	The
T27152	3697-3704	NN	denotes	amounts
T27153	3705-3707	IN	denotes	of
T27154	3708-3713	NN	denotes	GATA3
T27155	3714-3721	NN	denotes	protein
T27156	3722-3724	IN	denotes	in
T27157	3725-3728	DT	denotes	the
T27158	3729-3741	NN	denotes	precipitates
T27159	3742-3746	VB	denotes	were
T27160	3747-3755	VB	denotes	assessed
T27161	3756-3758	IN	denotes	by
T27162	3759-3773	NN	denotes	immunoblotting
T27163	3774-3778	IN	denotes	with
T27164	3779-3789	JJ	denotes	anti-GATA3
T27165	3790-3793	NN	denotes	mAb
T27166	3795-3800	JJ	denotes	Total
T27167	3801-3808	JJ	denotes	nuclear
T27168	3809-3817	NN	denotes	extracts
T27169	3818-3822	VB	denotes	were
T27170	3823-3827	RB	denotes	also
T27171	3828-3831	VB	denotes	run
T27172	3832-3834	IN	denotes	as
T27173	3835-3843	NN	denotes	controls
T27174	3845-3849	NN	denotes	Data
T27175	3850-3853	VB	denotes	are
T27176	3854-3868	JJ	denotes	representative
T27177	3869-3871	IN	denotes	of
T27178	3872-3877	CD	denotes	three
T27179	3878-3887	JJ	denotes	different
T27180	3888-3899	NN	denotes	experiments
T27181	3901-3902	-LRB-	denotes	(
T27182	3902-3903	NN	denotes	F
T27183	3903-3904	-RRB-	denotes	)
T27184	3905-3910	NN	denotes	iTreg
T27185	3911-3913	CC	denotes	or
T27186	3914-3917	NN	denotes	Th2
T27187	3918-3923	NN	denotes	cells
T27188	3924-3928	VB	denotes	were
T27189	3929-3937	VB	denotes	analyzed
T27190	3938-3940	IN	denotes	by
T27191	3941-3945	NN	denotes	ChIP
T27192	3946-3949	IN	denotes	for
T27193	3950-3955	NN	denotes	GATA3
T27194	3956-3963	NN	denotes	binding
T27195	3964-3966	TO	denotes	to
T27196	3967-3970	DT	denotes	the
T27197	3971-3976	NN	denotes	FOXP3
T27198	3977-3985	NN	denotes	promoter
T27199	3987-3990	DT	denotes	The
T27200	3991-3998	NN	denotes	“input”
T27201	3999-4009	VB	denotes	represents
T27202	4010-4013	NN	denotes	PCR
T27203	4014-4027	NN	denotes	amplification
T27204	4028-4030	IN	denotes	of
T27205	4031-4034	DT	denotes	the
T27206	4035-4040	JJ	denotes	total
T27207	4041-4047	NN	denotes	sample
T27208	4047-4048	-COMMA-	denotes	,
T27209	4049-4054	WDT	denotes	which
T27210	4055-4058	VB	denotes	was
T27211	4059-4062	RB	denotes	not
T27212	4063-4072	VB	denotes	subjected
T27213	4073-4075	TO	denotes	to
T27214	4076-4079	DT	denotes	any
T27215	4080-4093	NN	denotes	precipitation
T27216	4095-4102	NN	denotes	Results
T27217	4103-4106	VB	denotes	are
T27218	4107-4121	JJ	denotes	representative
T27219	4122-4124	IN	denotes	of
T27220	4125-4130	CD	denotes	three
T27221	4131-4142	JJ	denotes	independent
T27222	4143-4154	NN	denotes	experiments
R8620	T11599	T11600	arg1Of	GATA3,Represses
R8621	T11603	T11600	arg2Of	Promoter,Represses
R8622	T11603	T11601	arg1Of	Promoter,the
R8623	T11603	T11602	arg1Of	Promoter,FOXP3
R8624	T11605	T11604	arg1Of	investigate,To
R8625	T11608	T11605	arg2Of	mechanism,investigate
R8626	T11608	T11606	arg1Of	mechanism,the
R8627	T11608	T11607	arg1Of	mechanism,molecular
R8628	T11608	T11609	arg1Of	mechanism,of
R8629	T11611	T11609	arg2Of	repression,of
R8630	T11611	T11610	arg1Of	repression,GATA3-mediated
R8631	T11611	T11612	arg1Of	repression,of
R8632	T11614	T11612	arg2Of	FOXP3,of
R8633	T11614	T11613	arg1Of	FOXP3,human
R8634	T11619	T11616	arg1Of	promoter,the
R8635	T11619	T11617	arg1Of	promoter,human
R8636	T11619	T11618	arg1Of	promoter,FOXP3
R8637	T11619	T11620	arg1Of	promoter,was
R8638	T11619	T11621	arg2Of	promoter,studied
R8639	T11621	T11620	arg2Of	studied,was
R8640	T11621	T11622	arg1Of	studied,and
R8641	T11622	T11604	modOf	and,To
R8642	T11622	T11615	arg1Of	and,","
R8643	T11626	T11623	arg1Of	site,a
R8644	T11626	T11624	arg1Of	site,palindromic
R8645	T11626	T11625	arg1Of	site,binding
R8646	T11626	T11627	arg1Of	site,for
R8647	T11626	T11629	arg1Of	site,was
R8648	T11626	T11630	arg2Of	site,discovered
R8649	T11628	T11627	arg2Of	GATA3,for
R8650	T11630	T11622	arg2Of	discovered,and
R8651	T11630	T11629	arg2Of	discovered,was
R8652	T11633	T11631	arg1Of	site,The
R8653	T11633	T11632	arg1Of	site,GATA-binding
R8654	T11633	T11634	arg1Of	site,is
R8655	T11633	T11635	arg1Of	site,located
R8656	T11634	T11647	arg1Of	is,[
R8657	T11635	T11634	arg2Of	located,is
R8658	T11635	T11638	arg1Of	located,upstream
R8659	T11637	T11636	arg1Of	bp,303
R8660	T11638	T11637	arg1Of	upstream,bp
R8661	T11638	T11639	arg1Of	upstream,from
R8662	T11643	T11639	arg2Of	site,from
R8663	T11643	T11640	arg1Of	site,the
R8664	T11643	T11641	arg1Of	site,transcription
R8665	T11643	T11642	arg1Of	site,start
R8666	T11643	T11644	arg1Of	site,(
R8667	T11645	T11644	arg2Of	TSS,(
R8668	T11646	T11644	arg3Of	),(
R8669	T11648	T11647	arg2Of	24,[
R8670	T11649	T11647	arg3Of	],[
R8671	T11651	T11650	arg1Of	site,This
R8672	T11651	T11652	arg1Of	site,is
R8673	T11651	T11654	arg2Of	site,conserved
R8674	T11651	T11667	arg1Of	site,may
R8675	T11651	T11669	arg1Of	site,play
R8676	T11654	T11652	arg2Of	conserved,is
R8677	T11654	T11653	arg1Of	conserved,highly
R8678	T11654	T11655	arg1Of	conserved,between
R8679	T11654	T11666	arg1Of	conserved,and
R8680	T11656	T11657	arg1Of	humans,","
R8681	T11657	T11660	arg1Of	",",and
R8682	T11658	T11657	arg2Of	mice,","
R8683	T11660	T11655	arg2Of	and,between
R8684	T11660	T11659	arg1Of	and,","
R8685	T11661	T11660	arg2Of	rats,and
R8686	T11661	T11662	arg1Of	rats,(
R8687	T11664	T11662	arg2Of	S4,(
R8688	T11664	T11663	arg1Of	S4,Figure
R8689	T11665	T11662	arg3Of	),(
R8690	T11669	T11666	arg2Of	play,and
R8691	T11669	T11667	arg2Of	play,may
R8692	T11669	T11668	arg1Of	play,therefore
R8693	T11669	T11673	arg1Of	play,in
R8694	T11672	T11669	arg2Of	role,play
R8695	T11672	T11670	arg1Of	role,an
R8696	T11672	T11671	arg1Of	role,important
R8697	T11675	T11673	arg2Of	regulation,in
R8698	T11675	T11674	arg1Of	regulation,FOXP3
R8699	T11678	T11676	arg1Of	relevance,The
R8700	T11678	T11677	arg1Of	relevance,functional
R8701	T11678	T11679	arg1Of	relevance,of
R8702	T11678	T11682	arg1Of	relevance,was
R8703	T11678	T11683	arg2Of	relevance,studied
R8704	T11681	T11679	arg2Of	site,of
R8705	T11681	T11680	arg1Of	site,this
R8706	T11683	T11682	arg2Of	studied,was
R8707	T11684	T11683	arg3Of	using,studied
R8708	T11684	T11688	arg1Of	using,[
R8709	T11687	T11684	arg2Of	construct,using
R8710	T11687	T11685	arg1Of	construct,a
R8711	T11687	T11686	arg1Of	construct,FOXP3-promoter
R8712	T11689	T11688	arg2Of	24,[
R8713	T11690	T11688	arg3Of	],[
R8714	T11691	T11692	arg1Of	We,transfected
R8715	T11692	T11722	arg1Of	transfected,and
R8716	T11697	T11693	arg1Of	cells,human
R8717	T11697	T11694	arg1Of	cells,primary
R8718	T11697	T11695	arg1Of	cells,CD4+
R8719	T11697	T11696	arg1Of	cells,T
R8720	T11697	T11698	arg1Of	cells,","
R8721	T11698	T11705	arg1Of	",",and
R8722	T11700	T11699	arg1Of	vitro,in
R8723	T11703	T11698	arg2Of	cells,","
R8724	T11703	T11700	arg1Of	cells,vitro
R8725	T11703	T11701	arg2Of	cells,differentiated
R8726	T11703	T11702	arg1Of	cells,Th2
R8727	T11705	T11692	arg2Of	and,transfected
R8728	T11705	T11704	arg1Of	and,","
R8729	T11707	T11705	arg2Of	cells,and
R8730	T11707	T11706	arg1Of	cells,Jurkat
R8731	T11707	T11708	arg1Of	cells,(
R8732	T11710	T11709	arg1Of	cells,Jurkat
R8733	T11710	T11711	arg1Of	cells,are
R8734	T11710	T11712	arg2Of	cells,known
R8735	T11710	T11715	arg1Of	cells,express
R8736	T11712	T11708	arg2Of	known,(
R8737	T11712	T11711	arg2Of	known,are
R8738	T11715	T11712	arg3Of	express,known
R8739	T11715	T11713	arg1Of	express,to
R8740	T11715	T11714	arg1Of	express,constitutively
R8741	T11715	T11717	arg1Of	express,[
R8742	T11716	T11715	arg2Of	GATA3,express
R8743	T11718	T11717	arg2Of	"25,26",[
R8744	T11719	T11717	arg3Of	],[
R8745	T11720	T11708	arg3Of	),(
R8746	T11722	T11721	arg1Of	and,","
R8747	T11723	T11724	arg1Of	we,measured
R8748	T11724	T11722	arg2Of	measured,and
R8749	T11727	T11724	arg2Of	activity,measured
R8750	T11727	T11725	arg1Of	activity,FOXP3
R8751	T11727	T11726	arg1Of	activity,promoter
R8752	T11729	T11728	arg1Of	promoter,The
R8753	T11729	T11730	arg1Of	promoter,was
R8754	T11729	T11732	arg1Of	promoter,active
R8755	T11730	T11731	arg1Of	was,not
R8756	T11730	T11733	arg1Of	was,in
R8757	T11730	T11740	arg1Of	was,in
R8758	T11730	T11747	arg1Of	was,whereas
R8759	T11732	T11730	arg2Of	active,was
R8760	T11733	T11739	arg1Of	in,or
R8761	T11738	T11733	arg2Of	Jurkat,in
R8762	T11738	T11734	arg1Of	Jurkat,the
R8763	T11738	T11735	arg1Of	Jurkat,GATA3-expressing
R8764	T11738	T11736	arg1Of	Jurkat,cell
R8765	T11738	T11737	arg1Of	Jurkat,line
R8766	T11740	T11739	arg2Of	in,or
R8767	T11742	T11741	arg1Of	in,the
R8768	T11745	T11740	arg2Of	cells,in
R8769	T11745	T11742	arg1Of	cells,in
R8770	T11745	T11743	arg1Of	cells,vitro-differentiated
R8771	T11745	T11744	arg1Of	cells,Th2
R8772	T11747	T11746	arg1Of	whereas,","
R8773	T11749	T11748	arg1Of	construct,the
R8774	T11749	T11750	arg1Of	construct,was
R8775	T11749	T11751	arg1Of	construct,active
R8776	T11750	T11747	arg2Of	was,whereas
R8777	T11751	T11750	arg2Of	active,was
R8778	T11751	T11752	arg1Of	active,in
R8779	T11755	T11752	arg2Of	cells,in
R8780	T11755	T11753	arg1Of	cells,the
R8781	T11755	T11754	arg1Of	cells,CD4
R8782	T11755	T11756	arg1Of	cells,","
R8783	T11755	T11757	arg1Of	cells,which
R8784	T11755	T11758	arg1Of	cells,express
R8785	T11761	T11758	arg2Of	amount,express
R8786	T11761	T11759	arg1Of	amount,a
R8787	T11761	T11760	arg1Of	amount,lower
R8788	T11761	T11762	arg1Of	amount,of
R8789	T11763	T11762	arg2Of	GATA3,of
R8790	T11763	T11764	arg1Of	GATA3,(
R8791	T11766	T11764	arg2Of	8A,(
R8792	T11766	T11765	arg1Of	8A,Figure
R8793	T11767	T11764	arg3Of	),(
R8794	T11768	T11769	arg1Of	Overexpression,of
R8795	T11768	T11771	arg1Of	Overexpression,in
R8796	T11768	T11775	arg1Of	Overexpression,diminished
R8797	T11770	T11769	arg2Of	GATA3,of
R8798	T11774	T11771	arg2Of	cells,in
R8799	T11774	T11772	arg1Of	cells,naive
R8800	T11774	T11773	arg1Of	cells,T
R8801	T11775	T11782	arg1Of	diminished,compared
R8802	T11777	T11775	arg2Of	activity,diminished
R8803	T11777	T11776	arg1Of	activity,luciferase
R8804	T11777	T11778	arg1Of	activity,of
R8805	T11781	T11778	arg2Of	promoter,of
R8806	T11781	T11779	arg1Of	promoter,the
R8807	T11781	T11780	arg1Of	promoter,FOXP3
R8808	T11783	T11782	arg2Of	with,compared
R8809	T11786	T11783	arg2Of	vector,with
R8810	T11786	T11784	arg1Of	vector,the
R8811	T11786	T11785	arg1Of	vector,control
R8812	T11786	T11787	arg1Of	vector,(
R8813	T11789	T11787	arg2Of	8B,(
R8814	T11789	T11788	arg1Of	8B,Figure
R8815	T11790	T11787	arg3Of	),(
R8816	T11793	T11791	arg1Of	address,To
R8817	T11793	T11792	arg1Of	address,further
R8818	T11795	T11793	arg2Of	function,address
R8819	T11795	T11794	arg1Of	function,the
R8820	T11795	T11796	arg1Of	function,of
R8821	T11799	T11796	arg2Of	site,of
R8822	T11799	T11797	arg1Of	site,the
R8823	T11799	T11798	arg1Of	site,GATA3
R8824	T11801	T11793	arg1Of	we,address
R8825	T11801	T11802	arg1Of	we,inserted
R8826	T11802	T11791	modOf	inserted,To
R8827	T11802	T11800	arg1Of	inserted,","
R8828	T11805	T11802	arg2Of	mutation,inserted
R8829	T11805	T11803	arg1Of	mutation,a
R8830	T11805	T11804	arg1Of	mutation,site-specific
R8831	T11805	T11806	arg1Of	mutation,deleting
R8832	T11809	T11806	arg2Of	site,deleting
R8833	T11809	T11807	arg1Of	site,the
R8834	T11809	T11808	arg1Of	site,GATA3-binding
R8835	T11811	T11810	arg1Of	mutation,This
R8836	T11811	T11812	arg1Of	mutation,increased
R8837	T11812	T11815	arg1Of	increased,by
R8838	T11812	T11817	arg1Of	increased,in
R8839	T11812	T11822	arg1Of	increased,","
R8840	T11812	T11823	arg1Of	increased,whereas
R8841	T11814	T11812	arg2Of	activity,increased
R8842	T11814	T11813	arg1Of	activity,luciferase
R8843	T11816	T11815	arg2Of	3-fold,by
R8844	T11821	T11817	arg2Of	cells,in
R8845	T11821	T11818	arg1Of	cells,memory
R8846	T11821	T11819	arg1Of	cells,CD4+CD45RO+
R8847	T11821	T11820	arg1Of	cells,T
R8848	T11825	T11824	arg1Of	difference,no
R8849	T11825	T11826	arg1Of	difference,was
R8850	T11825	T11827	arg2Of	difference,observed
R8851	T11827	T11823	arg2Of	observed,whereas
R8852	T11827	T11826	arg2Of	observed,was
R8853	T11827	T11828	arg1Of	observed,in
R8854	T11827	T11836	arg1Of	observed,","
R8855	T11827	T11837	modOf	observed,revealing
R8856	T11831	T11830	arg2Of	GATA3–,(
R8857	T11832	T11830	arg3Of	),(
R8858	T11835	T11828	arg2Of	cells,in
R8859	T11835	T11829	arg1Of	cells,naive
R8860	T11835	T11830	arg1Of	cells,(
R8861	T11835	T11833	arg1Of	cells,CD4+CD45RA+
R8862	T11835	T11834	arg1Of	cells,T
R8863	T11840	T11837	arg2Of	activity,revealing
R8864	T11840	T11838	arg1Of	activity,a
R8865	T11840	T11839	arg1Of	activity,repressor
R8866	T11840	T11841	arg1Of	activity,of
R8867	T11840	T11843	arg1Of	activity,on
R8868	T11842	T11841	arg2Of	GATA3,of
R8869	T11846	T11843	arg2Of	promoter,on
R8870	T11846	T11844	arg1Of	promoter,the
R8871	T11846	T11845	arg1Of	promoter,FOXP3
R8872	T11846	T11847	arg1Of	promoter,(
R8873	T11849	T11847	arg2Of	8C,(
R8874	T11849	T11848	arg1Of	8C,Figure
R8875	T11850	T11847	arg3Of	),(
R8876	T11852	T11853	arg1Of	GATA3,binds
R8877	T11853	T11851	arg1Of	binds,Furthermore
R8878	T11853	T11854	arg1Of	binds,directly
R8879	T11853	T11855	arg1Of	binds,to
R8880	T11853	T11859	arg1Of	binds,as
R8881	T11858	T11855	arg2Of	promoter,to
R8882	T11858	T11856	arg1Of	promoter,the
R8883	T11858	T11857	arg1Of	promoter,FOXP3
R8884	T11860	T11859	arg2Of	investigated,as
R8885	T11863	T11860	arg1Of	assay,investigated
R8886	T11863	T11861	arg2Of	assay,by
R8887	T11863	T11862	arg1Of	assay,pull-down
R8888	T11865	T11864	arg1Of	cells,HEK
R8889	T11865	T11866	arg1Of	cells,were
R8890	T11865	T11868	arg2Of	cells,transfected
R8891	T11868	T11866	arg2Of	transfected,were
R8892	T11868	T11867	arg1Of	transfected,transiently
R8893	T11868	T11869	arg1Of	transfected,with
R8894	T11868	T11876	arg1Of	transfected,and
R8895	T11870	T11871	arg1Of	GATA3,or
R8896	T11871	T11869	arg2Of	or,with
R8897	T11874	T11871	arg2Of	vector,or
R8898	T11874	T11872	arg1Of	vector,a
R8899	T11874	T11873	arg1Of	vector,control
R8900	T11876	T11875	arg1Of	and,","
R8901	T11878	T11877	arg1Of	amounts,increasing
R8902	T11878	T11879	arg1Of	amounts,of
R8903	T11878	T11881	arg1Of	amounts,were
R8904	T11878	T11882	arg2Of	amounts,incubated
R8905	T11880	T11879	arg2Of	lysates,of
R8906	T11882	T11876	arg2Of	incubated,and
R8907	T11882	T11881	arg2Of	incubated,were
R8908	T11882	T11883	arg1Of	incubated,with
R8909	T11884	T11883	arg2Of	oligonucleotides,with
R8910	T11884	T11885	arg1Of	oligonucleotides,containing
R8911	T11888	T11886	arg1Of	site,the
R8912	T11888	T11887	arg1Of	site,GATA3
R8913	T11888	T11889	arg1Of	site,of
R8914	T11888	T11893	arg1Of	site,or
R8915	T11892	T11889	arg2Of	promoter,of
R8916	T11892	T11890	arg1Of	promoter,the
R8917	T11892	T11891	arg1Of	promoter,FOXP3
R8918	T11893	T11885	arg2Of	or,containing
R8919	T11896	T11893	arg2Of	oligonucleotide,or
R8920	T11896	T11894	arg1Of	oligonucleotide,a
R8921	T11896	T11895	arg1Of	oligonucleotide,control
R8922	T11896	T11897	arg1Of	oligonucleotide,with
R8923	T11901	T11897	arg2Of	site,with
R8924	T11901	T11898	arg1Of	site,a
R8925	T11901	T11899	arg2Of	site,mutated
R8926	T11901	T11900	arg1Of	site,GATA3-binding
R8927	T11904	T11902	arg2Of	pull-down,After
R8928	T11904	T11903	arg1Of	pull-down,the
R8929	T11907	T11906	arg1Of	binding,GATA3
R8930	T11907	T11908	arg1Of	binding,was
R8931	T11907	T11909	arg2Of	binding,detected
R8932	T11909	T11902	arg1Of	detected,After
R8933	T11909	T11905	arg1Of	detected,","
R8934	T11909	T11908	arg2Of	detected,was
R8935	T11912	T11909	arg1Of	blot,detected
R8936	T11912	T11910	arg2Of	blot,by
R8937	T11912	T11911	arg1Of	blot,Western
R8938	T11917	T11915	arg1Of	cells,GATA3-expressing
R8939	T11917	T11916	arg1Of	cells,Th2
R8940	T11917	T11918	arg1Of	cells,and
R8941	T11918	T11921	arg1Of	and,were
R8942	T11918	T11922	arg2Of	and,subjected
R8943	T11920	T11918	arg2Of	cells,and
R8944	T11920	T11919	arg1Of	cells,iTreg
R8945	T11922	T11913	arg1Of	subjected,Similarly
R8946	T11922	T11914	arg1Of	subjected,","
R8947	T11922	T11921	arg2Of	subjected,were
R8948	T11922	T11923	arg1Of	subjected,to
R8949	T11925	T11923	arg2Of	approach,to
R8950	T11925	T11924	arg1Of	approach,this
R8951	T11928	T11926	arg1Of	cells,Only
R8952	T11928	T11927	arg1Of	cells,HEK
R8953	T11928	T11929	arg1Of	cells,overexpressing
R8954	T11928	T11934	arg1Of	cells,showed
R8955	T11930	T11931	arg1Of	GATA3,and
R8956	T11932	T11931	arg2Of	Th2,and
R8957	T11933	T11929	arg2Of	cells,overexpressing
R8958	T11933	T11930	arg1Of	cells,GATA3
R8959	T11933	T11932	arg1Of	cells,Th2
R8960	T11936	T11934	arg2Of	activity,showed
R8961	T11936	T11935	arg1Of	activity,GATA3-binding
R8962	T11936	T11937	arg1Of	activity,(
R8963	T11939	T11938	arg1Of	8D,Figure
R8964	T11939	T11940	arg1Of	8D,and
R8965	T11940	T11937	arg2Of	and,(
R8966	T11941	T11940	arg2Of	8E,and
R8967	T11942	T11937	arg3Of	),(
R8968	T11944	T11943	arg1Of	experiments,These
R8969	T11944	T11945	arg1Of	experiments,demonstrated
R8970	T11947	T11948	arg1Of	GATA3,binds
R8971	T11948	T11945	arg2Of	binds,demonstrated
R8972	T11948	T11946	arg1Of	binds,that
R8973	T11952	T11948	arg2Of	promoter,binds
R8974	T11952	T11949	arg1Of	promoter,the
R8975	T11952	T11950	arg1Of	promoter,palindromic
R8976	T11952	T11951	arg1Of	promoter,FOXP3
R8977	T11954	T11953	arg1Of	gain,To
R8978	T11955	T11954	arg2Of	insights,gain
R8979	T11955	T11956	arg1Of	insights,into
R8980	T11959	T11958	arg1Of	vivo,in
R8981	T11960	T11956	arg2Of	situation,into
R8982	T11960	T11957	arg1Of	situation,the
R8983	T11960	T11959	arg1Of	situation,vivo
R8984	T11962	T11954	arg1Of	we,gain
R8985	T11962	T11963	arg1Of	we,performed
R8986	T11962	T11970	arg1Of	we,using
R8987	T11962	T11975	arg1Of	we,showed
R8988	T11963	T11970	modOf	performed,using
R8989	T11963	T11974	arg1Of	performed,and
R8990	T11966	T11963	arg2Of	immunoprecipitation,performed
R8991	T11966	T11964	arg1Of	immunoprecipitation,a
R8992	T11966	T11965	arg1Of	immunoprecipitation,chromatin
R8993	T11966	T11967	arg1Of	immunoprecipitation,(
R8994	T11968	T11967	arg2Of	ChIP,(
R8995	T11969	T11967	arg3Of	),(
R8996	T11973	T11970	arg2Of	antibody,using
R8997	T11973	T11971	arg1Of	antibody,an
R8998	T11973	T11972	arg1Of	antibody,anti-GATA3
R8999	T11974	T11953	modOf	and,To
R9000	T11974	T11961	arg1Of	and,","
R9001	T11975	T11974	arg2Of	showed,and
R9002	T11977	T11978	arg1Of	GATA3,binds
R9003	T11978	T11975	arg2Of	binds,showed
R9004	T11978	T11976	arg1Of	binds,that
R9005	T11978	T11979	arg1Of	binds,to
R9006	T11978	T11990	arg1Of	binds,in
R9007	T11979	T11988	arg1Of	to,but
R9008	T11983	T11979	arg2Of	region,to
R9009	T11983	T11980	arg1Of	region,the
R9010	T11983	T11981	arg1Of	region,FOXP3
R9011	T11983	T11982	arg1Of	region,promoter
R9012	T11983	T11984	arg1Of	region,in
R9013	T11986	T11984	arg2Of	cells,in
R9014	T11986	T11985	arg1Of	cells,Th2
R9015	T11988	T11987	arg1Of	but,","
R9016	T11990	T11988	arg2Of	in,but
R9017	T11990	T11989	arg1Of	in,not
R9018	T11992	T11990	arg2Of	cells,in
R9019	T11992	T11991	arg1Of	cells,iTreg
R9020	T11992	T11993	arg1Of	cells,(
R9021	T11995	T11993	arg2Of	7F,(
R9022	T11995	T11994	arg1Of	7F,Figure
R9023	T11996	T11993	arg3Of	),(
R9024	T11997	T11998	arg1Of	Taken,together
R9025	T12000	T11999	arg1Of	data,these
R9026	T12000	T12001	arg1Of	data,demonstrate
R9027	T12001	T11997	modOf	demonstrate,Taken
R9028	T12004	T12003	arg1Of	GATA3-binding,the
R9029	T12004	T12005	arg1Of	GATA3-binding,to
R9030	T12004	T12009	arg1Of	GATA3-binding,is
R9031	T12004	T12010	arg1Of	GATA3-binding,repressing
R9032	T12008	T12005	arg2Of	promoter,to
R9033	T12008	T12006	arg1Of	promoter,the
R9034	T12008	T12007	arg1Of	promoter,FOXP3
R9035	T12010	T12001	arg2Of	repressing,demonstrate
R9036	T12010	T12002	arg1Of	repressing,that
R9037	T12010	T12009	arg2Of	repressing,is
R9038	T12012	T12010	arg2Of	expression,repressing
R9039	T12012	T12011	arg1Of	expression,FOXP3
R19818	T26944	T26945	arg1Of	GATA3,Represses
R19822	T26949	T26945	arg2Of	Promoter,Represses
R19827	T26954	T26958	arg1Of	",",and
R19829	T26956	T26955	arg1Of	cells,Th2
R19830	T26958	T26957	arg1Of	and,","
R19831	T26958	T26963	arg1Of	and,were
R19832	T26958	T26964	arg2Of	and,transfected
R19833	T26962	T26958	arg2Of	cells,and
R19834	T26962	T26959	arg1Of	cells,human
R19835	T26962	T26960	arg1Of	cells,primary
R19836	T26962	T26961	arg1Of	cells,CD4
R19837	T26964	T26963	arg2Of	transfected,were
R19838	T26964	T26965	arg1Of	transfected,with
R19839	T26971	T26970	arg1Of	basic,pGL3
R19840	T26974	T26972	arg1Of	a,)
R19841	T26974	T26973	arg1Of	a,or
R19842	T26975	T26965	arg2Of	vector,with
R19843	T26975	T26966	arg1Of	vector,an
R19844	T26975	T26967	arg1Of	vector,empty
R19845	T26975	T26968	arg1Of	vector,vector
R19846	T26975	T26969	arg1Of	vector,(
R19847	T26975	T26971	arg1Of	vector,basic
R19848	T26975	T26974	arg1Of	vector,a
R19849	T26975	T26976	arg1Of	vector,containing
R19850	T26981	T26976	arg2Of	region,containing
R19851	T26981	T26977	arg1Of	region,the
R19852	T26981	T26978	arg1Of	region,putative
R19853	T26981	T26979	arg1Of	region,FOXP3
R19854	T26981	T26980	arg1Of	region,promoter
R19855	T26981	T26982	arg2Of	region,fused
R19856	T26982	T26983	arg1Of	fused,to
R19857	T26987	T26983	arg2Of	gene,to
R19858	T26987	T26984	arg1Of	gene,the
R19859	T26987	T26985	arg1Of	gene,luciferase
R19860	T26987	T26986	arg1Of	gene,reporter
R19861	T26988	T26989	arg1Of	Bars,show
R19862	T26989	T27006	arg1Of	show,;
R19863	T26993	T26989	arg2Of	SD,show
R19864	T26993	T26990	arg1Of	SD,the
R19865	T26993	T26991	arg1Of	SD,mean
R19866	T26993	T26992	arg1Of	SD,±
R19867	T26993	T26994	arg1Of	SD,of
R19868	T26997	T26994	arg2Of	units,of
R19869	T26997	T26995	arg1Of	units,arbitrary
R19870	T26997	T26996	arg1Of	units,light
R19871	T26997	T26998	arg2Of	units,normalized
R19872	T26998	T26999	arg1Of	normalized,for
R19873	T27001	T26999	arg2Of	luciferase,for
R19874	T27001	T27000	arg1Of	luciferase,renilla
R19875	T27001	T27002	arg1Of	luciferase,of
R19876	T27005	T27002	arg2Of	experiments,of
R19877	T27005	T27003	arg1Of	experiments,four
R19878	T27005	T27004	arg1Of	experiments,independent
R19879	T27007	T27008	arg1Of	samples,were
R19880	T27007	T27009	arg2Of	samples,measured
R19881	T27009	T27006	arg2Of	measured,;
R19882	T27009	T27008	arg2Of	measured,were
R19883	T27009	T27010	arg1Of	measured,in
R19884	T27011	T27010	arg2Of	triplicates,in
R19885	T27013	T27012	arg2Of	B,(
R19886	T27014	T27012	arg3Of	),(
R19887	T27018	T27012	arg1Of	cells,(
R19888	T27018	T27015	arg1Of	cells,Naive
R19889	T27018	T27016	arg1Of	cells,CD4
R19890	T27018	T27017	arg1Of	cells,T
R19891	T27018	T27019	arg1Of	cells,were
R19892	T27018	T27020	arg2Of	cells,transfected
R19893	T27020	T27019	arg2Of	transfected,were
R19894	T27020	T27021	arg1Of	transfected,with
R19895	T27026	T27022	arg1Of	construct,the
R19896	T27026	T27023	arg1Of	construct,FOXP3
R19897	T27026	T27024	arg1Of	construct,promoter
R19898	T27026	T27025	arg1Of	construct,reporter
R19899	T27026	T27028	arg1Of	construct,with
R19900	T27028	T27021	arg2Of	with,with
R19901	T27028	T27027	arg1Of	with,together
R19902	T27032	T27029	arg1Of	vector,a
R19903	T27032	T27030	arg1Of	vector,GATA3
R19904	T27032	T27031	arg1Of	vector,expression
R19905	T27032	T27033	arg1Of	vector,or
R19906	T27033	T27028	arg2Of	or,with
R19907	T27036	T27033	arg2Of	vector,or
R19908	T27036	T27034	arg1Of	vector,an
R19909	T27036	T27035	arg1Of	vector,empty
R19910	T27037	T27038	arg1Of	Bars,show
R19911	T27042	T27038	arg2Of	SD,show
R19912	T27042	T27039	arg1Of	SD,the
R19913	T27042	T27040	arg1Of	SD,mean
R19914	T27042	T27041	arg1Of	SD,±
R19915	T27042	T27043	arg1Of	SD,of
R19916	T27046	T27043	arg2Of	experiments,of
R19917	T27046	T27044	arg1Of	experiments,three
R19918	T27046	T27045	arg1Of	experiments,independent
R19919	T27048	T27047	arg2Of	C,(
R19920	T27049	T27047	arg3Of	),(
R19921	T27053	T27047	arg1Of	panel,(
R19922	T27053	T27050	arg1Of	panel,Naive
R19923	T27053	T27051	arg2Of	panel,(
R19924	T27053	T27052	arg1Of	panel,left
R19925	T27053	T27055	arg1Of	panel,or
R19926	T27054	T27051	arg3Of	),(
R19927	T27056	T27055	arg2Of	memory,or
R19928	T27056	T27057	arg1Of	memory,(
R19929	T27059	T27057	arg2Of	panel,(
R19930	T27059	T27058	arg1Of	panel,right
R19931	T27060	T27057	arg3Of	),(
R19932	T27063	T27051	arg1Of	cells,(
R19933	T27063	T27056	arg1Of	cells,memory
R19934	T27063	T27061	arg1Of	cells,CD4
R19935	T27063	T27062	arg1Of	cells,T
R19936	T27063	T27064	arg1Of	cells,were
R19937	T27063	T27065	arg2Of	cells,transfected
R19938	T27063	T27077	arg2Of	cells,activated
R19939	T27065	T27066	arg1Of	transfected,with
R19940	T27065	T27076	arg1Of	transfected,and
R19941	T27067	T27068	arg1Of	wild-type,or
R19942	T27068	T27066	arg2Of	or,with
R19943	T27071	T27070	arg1Of	mutated,GATA3
R19944	T27075	T27068	arg2Of	construct,or
R19945	T27075	T27069	arg1Of	construct,a
R19946	T27075	T27071	arg1Of	construct,mutated
R19947	T27075	T27072	arg1Of	construct,511-FOXP3
R19948	T27075	T27073	arg1Of	construct,promoter
R19949	T27075	T27074	arg1Of	construct,reporter
R19950	T27076	T27064	arg2Of	and,were
R19951	T27077	T27076	arg2Of	activated,and
R19952	T27077	T27078	arg1Of	activated,with
R19953	T27079	T27080	arg1Of	PMA,and
R19954	T27080	T27078	arg2Of	and,with
R19955	T27081	T27080	arg2Of	ionomycin,and
R19956	T27082	T27083	arg1Of	Bars,show
R19957	T27083	T27100	arg1Of	show,;
R19958	T27087	T27083	arg2Of	SD,show
R19959	T27087	T27084	arg1Of	SD,the
R19960	T27087	T27085	arg1Of	SD,mean
R19961	T27087	T27086	arg1Of	SD,±
R19962	T27087	T27088	arg1Of	SD,of
R19963	T27091	T27088	arg2Of	units,of
R19964	T27091	T27089	arg1Of	units,arbitrary
R19965	T27091	T27090	arg1Of	units,light
R19966	T27091	T27092	arg2Of	units,normalized
R19967	T27092	T27093	arg1Of	normalized,for
R19968	T27095	T27093	arg2Of	luciferase,for
R19969	T27095	T27094	arg1Of	luciferase,renilla
R19970	T27095	T27096	arg1Of	luciferase,of
R19971	T27099	T27096	arg2Of	experiments,of
R19972	T27099	T27097	arg1Of	experiments,eight
R19973	T27099	T27098	arg1Of	experiments,independent
R19974	T27101	T27102	arg1Of	samples,were
R19975	T27101	T27103	arg2Of	samples,measured
R19976	T27103	T27100	arg2Of	measured,;
R19977	T27103	T27102	arg2Of	measured,were
R19978	T27103	T27104	arg1Of	measured,in
R19979	T27105	T27104	arg2Of	triplicates,in
R19980	T27107	T27106	arg2Of	D,(
R19981	T27108	T27106	arg3Of	),(
R19982	T27110	T27106	arg1Of	extracts,(
R19983	T27110	T27109	arg1Of	extracts,Nuclear
R19984	T27110	T27111	arg1Of	extracts,were
R19985	T27110	T27112	arg2Of	extracts,prepared
R19986	T27112	T27111	arg2Of	prepared,were
R19987	T27112	T27113	arg1Of	prepared,from
R19988	T27115	T27113	arg2Of	cells,from
R19989	T27115	T27114	arg1Of	cells,HEK
R19990	T27115	T27116	arg2Of	cells,transfected
R19991	T27116	T27117	arg1Of	transfected,with
R19992	T27118	T27119	arg1Of	GATA3,or
R19993	T27119	T27117	arg2Of	or,with
R19994	T27122	T27119	arg2Of	vector,or
R19995	T27122	T27120	arg1Of	vector,an
R19996	T27122	T27121	arg1Of	vector,empty
R19997	T27125	T27124	arg2Of	E,(
R19998	T27126	T27124	arg3Of	),(
R19999	T27127	T27128	arg1Of	Th1,","
R20000	T27128	T27131	arg1Of	",",or
R20001	T27129	T27128	arg2Of	Th2,","
R20002	T27131	T27130	arg1Of	or,","
R20003	T27132	T27131	arg2Of	iTreg,or
R20004	T27133	T27134	arg1Of	cells,and
R20005	T27134	T27124	arg1Of	and,(
R20006	T27134	T27127	arg1Of	and,Th1
R20007	T27134	T27129	arg1Of	and,Th2
R20008	T27134	T27132	arg1Of	and,iTreg
R20009	T27134	T27137	arg1Of	and,precipitated
R20010	T27136	T27134	arg2Of	factors,and
R20011	T27136	T27135	arg1Of	factors,binding
R20012	T27137	T27111	modOf	precipitated,were
R20013	T27137	T27123	arg1Of	precipitated,","
R20014	T27138	T27137	arg2Of	using,precipitated
R20015	T27140	T27138	arg2Of	oligonucleotides,using
R20016	T27140	T27139	arg2Of	oligonucleotides,biotinylated
R20017	T27144	T27141	arg1Of	complexes,The
R20018	T27144	T27142	arg1Of	complexes,oligonucleotides–transcription
R20019	T27144	T27143	arg1Of	complexes,factor
R20020	T27144	T27145	arg1Of	complexes,were
R20021	T27144	T27146	arg2Of	complexes,separated
R20022	T27146	T27145	arg2Of	separated,were
R20023	T27146	T27147	arg1Of	separated,on
R20024	T27150	T27147	arg2Of	gel,on
R20025	T27150	T27148	arg1Of	gel,a
R20026	T27150	T27149	arg1Of	gel,SDS-PAGE
R20027	T27152	T27151	arg1Of	amounts,The
R20028	T27152	T27153	arg1Of	amounts,of
R20029	T27152	T27156	arg1Of	amounts,in
R20030	T27152	T27159	arg1Of	amounts,were
R20031	T27152	T27160	arg2Of	amounts,assessed
R20032	T27155	T27153	arg2Of	protein,of
R20033	T27155	T27154	arg1Of	protein,GATA3
R20034	T27158	T27156	arg2Of	precipitates,in
R20035	T27158	T27157	arg1Of	precipitates,the
R20036	T27160	T27159	arg2Of	assessed,were
R20037	T27162	T27160	arg1Of	immunoblotting,assessed
R20038	T27162	T27161	arg2Of	immunoblotting,by
R20039	T27162	T27163	arg1Of	immunoblotting,with
R20040	T27165	T27163	arg2Of	mAb,with
R20041	T27165	T27164	arg1Of	mAb,anti-GATA3
R20042	T27168	T27166	arg1Of	extracts,Total
R20043	T27168	T27167	arg1Of	extracts,nuclear
R20044	T27168	T27169	arg1Of	extracts,were
R20045	T27168	T27171	arg2Of	extracts,run
R20046	T27171	T27169	arg2Of	run,were
R20047	T27171	T27170	arg1Of	run,also
R20048	T27171	T27172	arg1Of	run,as
R20049	T27173	T27172	arg2Of	controls,as
R20050	T27174	T27175	arg1Of	Data,are
R20051	T27174	T27176	arg1Of	Data,representative
R20052	T27176	T27175	arg2Of	representative,are
R20053	T27176	T27177	arg1Of	representative,of
R20054	T27180	T27177	arg2Of	experiments,of
R20055	T27180	T27178	arg1Of	experiments,three
R20056	T27180	T27179	arg1Of	experiments,different
R20057	T27182	T27181	arg2Of	F,(
R20058	T27183	T27181	arg3Of	),(
R20059	T27184	T27185	arg1Of	iTreg,or
R20060	T27186	T27185	arg2Of	Th2,or
R20061	T27187	T27181	arg1Of	cells,(
R20062	T27187	T27184	arg1Of	cells,iTreg
R20063	T27187	T27186	arg1Of	cells,Th2
R20064	T27187	T27188	arg1Of	cells,were
R20065	T27187	T27189	arg2Of	cells,analyzed
R20066	T27189	T27188	arg2Of	analyzed,were
R20067	T27191	T27189	arg1Of	ChIP,analyzed
R20068	T27191	T27190	arg2Of	ChIP,by
R20069	T27191	T27192	arg1Of	ChIP,for
R20070	T27194	T27192	arg2Of	binding,for
R20071	T27194	T27193	arg1Of	binding,GATA3
R20072	T27194	T27195	arg1Of	binding,to
R20073	T27198	T27195	arg2Of	promoter,to
R20074	T27198	T27196	arg1Of	promoter,the
R20075	T27198	T27197	arg1Of	promoter,FOXP3
R20076	T27200	T27199	arg1Of	“input”,The
R20077	T27200	T27201	arg1Of	“input”,represents
R20078	T27203	T27201	arg2Of	amplification,represents
R20079	T27203	T27202	arg1Of	amplification,PCR
R20080	T27203	T27204	arg1Of	amplification,of
R20081	T27207	T27204	arg2Of	sample,of
R20082	T27207	T27205	arg1Of	sample,the
R20083	T27207	T27206	arg1Of	sample,total
R20084	T27207	T27208	arg1Of	sample,","
R20085	T27207	T27209	arg1Of	sample,which
R20086	T27207	T27210	arg1Of	sample,was
R20087	T27207	T27212	arg2Of	sample,subjected
R20088	T27212	T27210	arg2Of	subjected,was
R20089	T27212	T27211	arg1Of	subjected,not
R20090	T27212	T27213	arg1Of	subjected,to
R20091	T27215	T27213	arg2Of	precipitation,to
R20092	T27215	T27214	arg1Of	precipitation,any
R20093	T27216	T27217	arg1Of	Results,are
R20094	T27216	T27218	arg1Of	Results,representative
R20095	T27218	T27217	arg2Of	representative,are
R20096	T27218	T27219	arg1Of	representative,of
R20097	T27222	T27219	arg2Of	experiments,of
R20098	T27222	T27220	arg1Of	experiments,three
R20099	T27222	T27221	arg1Of	experiments,independent
R19819	T26949	T26946	arg1Of	Promoter,the
R19820	T26949	T26947	arg1Of	Promoter,Human
R19821	T26949	T26948	arg1Of	Promoter,FOXP3
R19823	T26951	T26950	arg2Of	A,(
R19824	T26952	T26950	arg3Of	),(
R19825	T26953	T26950	arg1Of	Jurkat,(
R19826	T26953	T26954	arg1Of	Jurkat,","
R19828	T26956	T26954	arg2Of	cells,","

bionlp-st-ge-2016-coref

Id	Subject	Object	Predicate	Lexical cue
T12013	308-317	Anaphor	denotes	This site
T12014	217-234	Antecedent	denotes	GATA-binding site
T12015	856-869	Anaphor	denotes	the construct
T12016	715-723	Antecedent	denotes	promoter
R9040	T12013	T12014	boundBy	This site,GATA-binding site
R9041	T12015	T12016	boundBy	the construct,promoter

bionlp-st-ge-2016-spacy-parsed

Id	Subject	Object	Predicate	Lexical cue
T12080	0-5	CD	denotes	GATA3
T12081	6-15	NNPS	denotes	Represses
T12082	16-19	DT	denotes	the
T12083	20-25	NNP	denotes	FOXP3
T12084	26-34	NNP	denotes	Promoter
T12085	35-37	TO	denotes	To
T12086	38-49	VB	denotes	investigate
T12087	50-53	DT	denotes	the
T12088	54-63	JJ	denotes	molecular
T12089	64-73	NN	denotes	mechanism
T12090	74-76	IN	denotes	of
T12091	77-91	JJ	denotes	GATA3-mediated
T12092	92-102	NN	denotes	repression
T12093	103-105	IN	denotes	of
T12094	106-111	JJ	denotes	human
T12095	112-117	NNP	denotes	FOXP3
T12096	117-118	,	denotes	,
T12097	119-122	DT	denotes	the
T12098	123-128	JJ	denotes	human
T12099	129-134	CD	denotes	FOXP3
T12100	135-143	NN	denotes	promoter
T12101	144-147	VBD	denotes	was
T12102	148-155	VBN	denotes	studied
T12103	156-159	CC	denotes	and
T12104	160-161	DT	denotes	a
T12105	162-173	JJ	denotes	palindromic
T12106	174-181	JJ	denotes	binding
T12107	182-186	NN	denotes	site
T12108	187-190	IN	denotes	for
T12109	191-196	NNP	denotes	GATA3
T12110	197-200	VBD	denotes	was
T12111	201-211	VBN	denotes	discovered
T12112	211-212	.	denotes	.
T12113	213-216	DT	denotes	The
T12114	217-229	JJ	denotes	GATA-binding
T12115	230-234	NN	denotes	site
T12116	235-237	VBZ	denotes	is
T12117	238-245	VBN	denotes	located
T12118	246-249	CD	denotes	303
T12119	250-252	NN	denotes	bp
T12120	253-261	RB	denotes	upstream
T12121	262-266	IN	denotes	from
T12122	267-270	DT	denotes	the
T12123	271-284	NN	denotes	transcription
T12124	285-290	VB	denotes	start
T12125	291-295	NN	denotes	site
T12126	296-297	-LRB-	denotes	(
T12127	297-300	NNP	denotes	TSS
T12128	300-301	-RRB-	denotes	)
T12129	302-303	NNP	denotes	[
T12130	303-305	CD	denotes	24
T12131	305-306	NNP	denotes	]
T12132	306-307	.	denotes	.
T12133	308-312	DT	denotes	This
T12134	313-317	NN	denotes	site
T12135	318-320	VBZ	denotes	is
T12136	321-327	RB	denotes	highly
T12137	328-337	VBN	denotes	conserved
T12138	338-345	IN	denotes	between
T12139	346-352	NNS	denotes	humans
T12140	352-353	,	denotes	,
T12141	354-358	NNS	denotes	mice
T12142	358-359	,	denotes	,
T12143	360-363	CC	denotes	and
T12144	364-368	NNS	denotes	rats
T12145	369-370	-LRB-	denotes	(
T12146	370-376	NN	denotes	Figure
T12147	377-379	CD	denotes	S4
T12148	379-380	-RRB-	denotes	)
T12149	381-384	CC	denotes	and
T12150	385-388	MD	denotes	may
T12151	389-398	RB	denotes	therefore
T12152	399-403	VB	denotes	play
T12153	404-406	DT	denotes	an
T12154	407-416	JJ	denotes	important
T12155	417-421	NN	denotes	role
T12156	422-424	IN	denotes	in
T12157	425-430	CD	denotes	FOXP3
T12158	431-441	NN	denotes	regulation
T12159	441-442	.	denotes	.
T12160	443-446	DT	denotes	The
T12161	447-457	JJ	denotes	functional
T12162	458-467	NN	denotes	relevance
T12163	468-470	IN	denotes	of
T12164	471-475	DT	denotes	this
T12165	476-480	NN	denotes	site
T12166	481-484	VBD	denotes	was
T12167	485-492	VBN	denotes	studied
T12168	493-498	VBG	denotes	using
T12169	499-500	DT	denotes	a
T12170	501-515	NN	denotes	FOXP3-promoter
T12171	516-525	VB	denotes	construct
T12172	526-527	NNP	denotes	[
T12173	527-529	CD	denotes	24
T12174	529-530	NNP	denotes	]
T12175	530-531	.	denotes	.
T12176	532-534	PRP	denotes	We
T12177	535-546	VBD	denotes	transfected
T12178	547-552	JJ	denotes	human
T12179	553-560	JJ	denotes	primary
T12180	561-564	NNP	denotes	CD4
T12181	564-565	CD	denotes	+
T12182	566-567	NNP	denotes	T
T12183	568-573	NNS	denotes	cells
T12184	573-574	,	denotes	,
T12185	575-577	IN	denotes	in
T12186	578-583	NN	denotes	vitro
T12187	584-598	VBD	denotes	differentiated
T12188	599-602	JJ	denotes	Th2
T12189	603-608	NNS	denotes	cells
T12190	608-609	,	denotes	,
T12191	610-613	CC	denotes	and
T12192	614-620	NNP	denotes	Jurkat
T12193	621-626	NNS	denotes	cells
T12194	627-628	-LRB-	denotes	(
T12195	628-634	NNP	denotes	Jurkat
T12196	635-640	NNS	denotes	cells
T12197	641-644	VBP	denotes	are
T12198	645-650	VBN	denotes	known
T12199	651-653	TO	denotes	to
T12200	654-668	RB	denotes	constitutively
T12201	669-676	VB	denotes	express
T12202	677-682	NNP	denotes	GATA3
T12203	683-684	NNP	denotes	[
T12204	684-689	CD	denotes	25,26
T12205	689-690	NNP	denotes	]
T12206	690-691	-RRB-	denotes	)
T12207	691-692	,	denotes	,
T12208	693-696	CC	denotes	and
T12209	697-699	PRP	denotes	we
T12210	700-708	VBD	denotes	measured
T12211	709-714	CD	denotes	FOXP3
T12212	715-723	NN	denotes	promoter
T12213	724-732	NN	denotes	activity
T12214	732-733	.	denotes	.
T12215	734-737	DT	denotes	The
T12216	738-746	NN	denotes	promoter
T12217	747-750	VBD	denotes	was
T12218	751-754	RB	denotes	not
T12219	755-761	JJ	denotes	active
T12220	762-764	IN	denotes	in
T12221	765-768	DT	denotes	the
T12222	769-785	JJ	denotes	GATA3-expressing
T12223	786-790	NN	denotes	cell
T12224	791-795	NN	denotes	line
T12225	796-802	NNP	denotes	Jurkat
T12226	803-805	CC	denotes	or
T12227	806-808	IN	denotes	in
T12228	809-812	DT	denotes	the
T12229	813-815	IN	denotes	in
T12230	816-836	JJ	denotes	vitro-differentiated
T12231	837-840	JJ	denotes	Th2
T12232	841-846	NNS	denotes	cells
T12233	846-847	,	denotes	,
T12234	848-855	IN	denotes	whereas
T12235	856-859	DT	denotes	the
T12236	860-869	VBP	denotes	construct
T12237	870-873	VBD	denotes	was
T12238	874-880	JJ	denotes	active
T12239	881-883	IN	denotes	in
T12240	884-887	DT	denotes	the
T12241	888-891	NNP	denotes	CD4
T12242	892-897	NNS	denotes	cells
T12243	897-898	,	denotes	,
T12244	899-904	WDT	denotes	which
T12245	905-912	VBP	denotes	express
T12246	913-914	DT	denotes	a
T12247	915-920	JJR	denotes	lower
T12248	921-927	NN	denotes	amount
T12249	928-930	IN	denotes	of
T12250	931-936	NNP	denotes	GATA3
T12251	937-938	-LRB-	denotes	(
T12252	938-944	NNP	denotes	Figure
T12253	945-947	NNP	denotes	8A
T12254	947-948	-RRB-	denotes	)
T12255	948-949	.	denotes	.
T12256	950-964	NNP	denotes	Overexpression
T12257	965-967	IN	denotes	of
T12258	968-973	NNP	denotes	GATA3
T12259	974-976	IN	denotes	in
T12260	977-982	JJ	denotes	naive
T12261	983-984	NNP	denotes	T
T12262	985-990	NNS	denotes	cells
T12263	991-1001	VBD	denotes	diminished
T12264	1002-1012	NN	denotes	luciferase
T12265	1013-1021	NN	denotes	activity
T12266	1022-1024	IN	denotes	of
T12267	1025-1028	DT	denotes	the
T12268	1029-1034	CD	denotes	FOXP3
T12269	1035-1043	NN	denotes	promoter
T12270	1044-1052	VBN	denotes	compared
T12271	1053-1057	IN	denotes	with
T12272	1058-1061	DT	denotes	the
T12273	1062-1069	NN	denotes	control
T12274	1070-1076	NN	denotes	vector
T12275	1077-1078	-LRB-	denotes	(
T12276	1078-1084	NN	denotes	Figure
T12277	1085-1087	NN	denotes	8B
T12278	1087-1088	-RRB-	denotes	)
T12279	1088-1089	.	denotes	.
T12280	1090-1092	TO	denotes	To
T12281	1093-1100	RBR	denotes	further
T12282	1101-1108	VB	denotes	address
T12283	1109-1112	DT	denotes	the
T12284	1113-1121	NN	denotes	function
T12285	1122-1124	IN	denotes	of
T12286	1125-1128	DT	denotes	the
T12287	1129-1134	NNP	denotes	GATA3
T12288	1135-1139	NN	denotes	site
T12289	1139-1140	,	denotes	,
T12290	1141-1143	PRP	denotes	we
T12291	1144-1152	VBD	denotes	inserted
T12292	1153-1154	DT	denotes	a
T12293	1155-1168	JJ	denotes	site-specific
T12294	1169-1177	NN	denotes	mutation
T12295	1178-1186	VBG	denotes	deleting
T12296	1187-1190	DT	denotes	the
T12297	1191-1204	JJ	denotes	GATA3-binding
T12298	1205-1209	NN	denotes	site
T12299	1209-1210	.	denotes	.
T12300	1211-1215	DT	denotes	This
T12301	1216-1224	NN	denotes	mutation
T12302	1225-1234	VBD	denotes	increased
T12303	1235-1245	NN	denotes	luciferase
T12304	1246-1254	NN	denotes	activity
T12305	1255-1257	IN	denotes	by
T12306	1258-1264	JJ	denotes	3-fold
T12307	1265-1267	IN	denotes	in
T12308	1268-1274	NN	denotes	memory
T12309	1275-1278	NNP	denotes	CD4
T12310	1278-1279	NNP	denotes	+
T12311	1279-1285	NNP	denotes	CD45RO
T12312	1285-1286	VBD	denotes	+
T12313	1287-1288	NNP	denotes	T
T12314	1289-1294	NNS	denotes	cells
T12315	1294-1295	,	denotes	,
T12316	1296-1303	IN	denotes	whereas
T12317	1304-1306	DT	denotes	no
T12318	1307-1317	NN	denotes	difference
T12319	1318-1321	VBD	denotes	was
T12320	1322-1330	VBN	denotes	observed
T12321	1331-1333	IN	denotes	in
T12322	1334-1339	JJ	denotes	naive
T12323	1340-1341	-LRB-	denotes	(
T12324	1341-1346	CD	denotes	GATA3
T12325	1347-1348	-RRB-	denotes	)
T12326	1349-1352	CD	denotes	CD4
T12327	1352-1353	CD	denotes	+
T12328	1353-1359	NNP	denotes	CD45RA
T12329	1359-1360	CD	denotes	+
T12330	1361-1362	NNP	denotes	T
T12331	1363-1368	NNS	denotes	cells
T12332	1368-1369	,	denotes	,
T12333	1370-1379	VBG	denotes	revealing
T12334	1380-1381	DT	denotes	a
T12335	1382-1391	NN	denotes	repressor
T12336	1392-1400	NN	denotes	activity
T12337	1401-1403	IN	denotes	of
T12338	1404-1409	NNP	denotes	GATA3
T12339	1410-1412	IN	denotes	on
T12340	1413-1416	DT	denotes	the
T12341	1417-1422	CD	denotes	FOXP3
T12342	1423-1431	NN	denotes	promoter
T12343	1432-1433	-LRB-	denotes	(
T12344	1433-1439	NN	denotes	Figure
T12345	1440-1442	NN	denotes	8C
T12346	1442-1443	-RRB-	denotes	)
T12347	1443-1444	.	denotes	.
T12348	1445-1456	RB	denotes	Furthermore
T12349	1457-1462	JJ	denotes	GATA3
T12350	1463-1468	NNS	denotes	binds
T12351	1469-1477	RB	denotes	directly
T12352	1478-1480	TO	denotes	to
T12353	1481-1484	DT	denotes	the
T12354	1485-1490	CD	denotes	FOXP3
T12355	1491-1499	NN	denotes	promoter
T12356	1500-1502	IN	denotes	as
T12357	1503-1515	VBN	denotes	investigated
T12358	1516-1518	IN	denotes	by
T12359	1519-1528	JJ	denotes	pull-down
T12360	1529-1534	NN	denotes	assay
T12361	1534-1535	.	denotes	.
T12362	1536-1539	NNP	denotes	HEK
T12363	1540-1545	NNS	denotes	cells
T12364	1546-1550	VBD	denotes	were
T12365	1551-1562	RB	denotes	transiently
T12366	1563-1574	VBN	denotes	transfected
T12367	1575-1579	IN	denotes	with
T12368	1580-1585	CD	denotes	GATA3
T12369	1586-1588	CC	denotes	or
T12370	1589-1590	DT	denotes	a
T12371	1591-1598	NN	denotes	control
T12372	1599-1605	NN	denotes	vector
T12373	1605-1606	,	denotes	,
T12374	1607-1610	CC	denotes	and
T12375	1611-1621	VBG	denotes	increasing
T12376	1622-1629	NNS	denotes	amounts
T12377	1630-1632	IN	denotes	of
T12378	1633-1640	NNS	denotes	lysates
T12379	1641-1645	VBD	denotes	were
T12380	1646-1655	VBN	denotes	incubated
T12381	1656-1660	IN	denotes	with
T12382	1661-1677	NNS	denotes	oligonucleotides
T12383	1678-1688	VBG	denotes	containing
T12384	1689-1692	DT	denotes	the
T12385	1693-1698	NNP	denotes	GATA3
T12386	1699-1703	NN	denotes	site
T12387	1704-1706	IN	denotes	of
T12388	1707-1710	DT	denotes	the
T12389	1711-1716	CD	denotes	FOXP3
T12390	1717-1725	NN	denotes	promoter
T12391	1726-1728	CC	denotes	or
T12392	1729-1730	DT	denotes	a
T12393	1731-1738	NN	denotes	control
T12394	1739-1754	NN	denotes	oligonucleotide
T12395	1755-1759	IN	denotes	with
T12396	1760-1761	DT	denotes	a
T12397	1762-1769	VBN	denotes	mutated
T12398	1770-1783	JJ	denotes	GATA3-binding
T12399	1784-1788	NN	denotes	site
T12400	1788-1789	.	denotes	.
T12401	1790-1795	IN	denotes	After
T12402	1796-1799	DT	denotes	the
T12403	1800-1809	JJ	denotes	pull-down
T12404	1809-1810	,	denotes	,
T12405	1811-1816	JJ	denotes	GATA3
T12406	1817-1824	JJ	denotes	binding
T12407	1825-1828	VBD	denotes	was
T12408	1829-1837	VBN	denotes	detected
T12409	1838-1840	IN	denotes	by
T12410	1841-1848	JJ	denotes	Western
T12411	1849-1853	NN	denotes	blot
T12412	1853-1854	.	denotes	.
T12413	1855-1864	RB	denotes	Similarly
T12414	1864-1865	,	denotes	,
T12415	1866-1882	JJ	denotes	GATA3-expressing
T12416	1883-1886	JJ	denotes	Th2
T12417	1887-1892	NNS	denotes	cells
T12418	1893-1896	CC	denotes	and
T12419	1897-1902	NNP	denotes	iTreg
T12420	1903-1908	NNS	denotes	cells
T12421	1909-1913	VBD	denotes	were
T12422	1914-1923	VBN	denotes	subjected
T12423	1924-1926	TO	denotes	to
T12424	1927-1931	DT	denotes	this
T12425	1932-1940	NN	denotes	approach
T12426	1940-1941	.	denotes	.
T12427	1942-1946	RB	denotes	Only
T12428	1947-1950	NNP	denotes	HEK
T12429	1951-1956	NNS	denotes	cells
T12430	1957-1971	VBG	denotes	overexpressing
T12431	1972-1977	NNP	denotes	GATA3
T12432	1978-1981	CC	denotes	and
T12433	1982-1985	NNP	denotes	Th2
T12434	1986-1991	NNS	denotes	cells
T12435	1992-1998	VBD	denotes	showed
T12436	1999-2012	JJ	denotes	GATA3-binding
T12437	2013-2021	NN	denotes	activity
T12438	2022-2023	-LRB-	denotes	(
T12439	2023-2029	NN	denotes	Figure
T12440	2030-2032	CD	denotes	8D
T12441	2033-2036	CC	denotes	and
T12442	2037-2039	CD	denotes	8E
T12443	2039-2040	-RRB-	denotes	)
T12444	2040-2041	.	denotes	.
T12445	2042-2047	DT	denotes	These
T12446	2048-2059	NNS	denotes	experiments
T12447	2060-2072	VBD	denotes	demonstrated
T12448	2073-2077	IN	denotes	that
T12449	2078-2083	NNP	denotes	GATA3
T12450	2084-2089	VBZ	denotes	binds
T12451	2090-2093	DT	denotes	the
T12452	2094-2105	JJ	denotes	palindromic
T12453	2106-2111	CD	denotes	FOXP3
T12454	2112-2120	NN	denotes	promoter
T12455	2120-2121	.	denotes	.
T12456	2122-2124	TO	denotes	To
T12457	2125-2129	VB	denotes	gain
T12458	2130-2138	NNS	denotes	insights
T12459	2139-2143	IN	denotes	into
T12460	2144-2147	DT	denotes	the
T12461	2148-2150	IN	denotes	in
T12462	2151-2155	NN	denotes	vivo
T12463	2156-2165	NN	denotes	situation
T12464	2165-2166	,	denotes	,
T12465	2167-2169	PRP	denotes	we
T12466	2170-2179	VBD	denotes	performed
T12467	2180-2181	DT	denotes	a
T12468	2182-2191	NN	denotes	chromatin
T12469	2192-2211	NN	denotes	immunoprecipitation
T12470	2212-2213	-LRB-	denotes	(
T12471	2213-2217	NNP	denotes	ChIP
T12472	2217-2218	-RRB-	denotes	)
T12473	2219-2224	VBG	denotes	using
T12474	2225-2227	DT	denotes	an
T12475	2228-2238	JJ	denotes	anti-GATA3
T12476	2239-2247	NN	denotes	antibody
T12477	2248-2251	CC	denotes	and
T12478	2252-2258	VBD	denotes	showed
T12479	2259-2263	IN	denotes	that
T12480	2264-2269	CD	denotes	GATA3
T12481	2270-2275	NNS	denotes	binds
T12482	2276-2278	TO	denotes	to
T12483	2279-2282	DT	denotes	the
T12484	2283-2288	CD	denotes	FOXP3
T12485	2289-2297	NN	denotes	promoter
T12486	2298-2304	NN	denotes	region
T12487	2305-2307	IN	denotes	in
T12488	2308-2311	JJ	denotes	Th2
T12489	2312-2317	NNS	denotes	cells
T12490	2317-2318	,	denotes	,
T12491	2319-2322	CC	denotes	but
T12492	2323-2326	RB	denotes	not
T12493	2327-2329	IN	denotes	in
T12494	2330-2335	NNP	denotes	iTreg
T12495	2336-2341	NNS	denotes	cells
T12496	2342-2343	-LRB-	denotes	(
T12497	2343-2349	NN	denotes	Figure
T12498	2350-2352	CD	denotes	7F
T12499	2352-2353	-RRB-	denotes	)
T12500	2353-2354	.	denotes	.
T12501	2355-2360	VBN	denotes	Taken
T12502	2361-2369	RB	denotes	together
T12503	2370-2375	DT	denotes	these
T12504	2376-2380	NNS	denotes	data
T12505	2381-2392	VBP	denotes	demonstrate
T12506	2393-2397	IN	denotes	that
T12507	2398-2401	DT	denotes	the
T12508	2402-2415	NN	denotes	GATA3-binding
T12509	2416-2418	TO	denotes	to
T12510	2419-2422	DT	denotes	the
T12511	2423-2428	CD	denotes	FOXP3
T12512	2429-2437	NN	denotes	promoter
T12513	2438-2440	VBZ	denotes	is
T12514	2441-2451	VBG	denotes	repressing
T12515	2452-2457	CD	denotes	FOXP3
T12516	2458-2468	NN	denotes	expression
T12517	2468-2469	.	denotes	.
T27256	2480-2485	CD	denotes	GATA3
T27257	2486-2495	NNPS	denotes	Represses
T27258	2496-2499	DT	denotes	the
T27259	2500-2505	NNP	denotes	Human
T27260	2506-2511	NNP	denotes	FOXP3
T27261	2512-2520	NNP	denotes	Promoter
T27262	2521-2522	-LRB-	denotes	(
T27263	2522-2523	NNP	denotes	A
T27264	2523-2524	-RRB-	denotes	)
T27265	2525-2531	NNP	denotes	Jurkat
T27266	2531-2532	,	denotes	,
T27267	2533-2536	NNP	denotes	Th2
T27268	2537-2542	NNS	denotes	cells
T27269	2542-2543	,	denotes	,
T27270	2544-2547	CC	denotes	and
T27271	2548-2553	JJ	denotes	human
T27272	2554-2561	JJ	denotes	primary
T27273	2562-2565	NNP	denotes	CD4
T27274	2566-2571	NNS	denotes	cells
T27275	2572-2576	VBD	denotes	were
T27276	2577-2588	VBN	denotes	transfected
T27277	2589-2593	IN	denotes	with
T27278	2594-2596	DT	denotes	an
T27279	2597-2602	JJ	denotes	empty
T27280	2603-2609	NN	denotes	vector
T27281	2610-2611	-LRB-	denotes	(
T27282	2611-2615	JJ	denotes	pGL3
T27283	2616-2621	JJ	denotes	basic
T27284	2621-2622	-RRB-	denotes	)
T27285	2623-2625	CC	denotes	or
T27286	2626-2627	DT	denotes	a
T27287	2628-2634	NN	denotes	vector
T27288	2635-2645	VBG	denotes	containing
T27289	2646-2649	DT	denotes	the
T27290	2650-2658	JJ	denotes	putative
T27291	2659-2664	CD	denotes	FOXP3
T27292	2665-2673	NN	denotes	promoter
T27293	2674-2680	NN	denotes	region
T27294	2681-2686	VBD	denotes	fused
T27295	2687-2689	TO	denotes	to
T27296	2690-2693	DT	denotes	the
T27297	2694-2704	NN	denotes	luciferase
T27298	2705-2713	NN	denotes	reporter
T27299	2714-2718	NN	denotes	gene
T27300	2718-2719	.	denotes	.
T27301	2720-2724	NNS	denotes	Bars
T27302	2725-2729	VBP	denotes	show
T27303	2730-2733	DT	denotes	the
T27304	2734-2738	JJ	denotes	mean
T27305	2739-2740	NN	denotes	±
T27306	2741-2743	NNP	denotes	SD
T27307	2744-2746	IN	denotes	of
T27308	2747-2756	JJ	denotes	arbitrary
T27309	2757-2762	JJ	denotes	light
T27310	2763-2768	NNS	denotes	units
T27311	2769-2779	VBN	denotes	normalized
T27312	2780-2783	IN	denotes	for
T27313	2784-2791	NN	denotes	renilla
T27314	2792-2802	NN	denotes	luciferase
T27315	2803-2805	IN	denotes	of
T27316	2806-2810	CD	denotes	four
T27317	2811-2822	JJ	denotes	independent
T27318	2823-2834	NNS	denotes	experiments
T27319	2834-2835	:	denotes	;
T27320	2836-2843	NNS	denotes	samples
T27321	2844-2848	VBD	denotes	were
T27322	2849-2857	VBN	denotes	measured
T27323	2858-2860	IN	denotes	in
T27324	2861-2872	NNS	denotes	triplicates
T27325	2872-2873	.	denotes	.
T27326	2874-2875	-LRB-	denotes	(
T27327	2875-2876	NNP	denotes	B
T27328	2876-2877	-RRB-	denotes	)
T27329	2878-2883	NNP	denotes	Naive
T27330	2884-2887	NNP	denotes	CD4
T27331	2888-2889	NNP	denotes	T
T27332	2890-2895	NNS	denotes	cells
T27333	2896-2900	VBD	denotes	were
T27334	2901-2912	VBN	denotes	transfected
T27335	2913-2917	IN	denotes	with
T27336	2918-2921	DT	denotes	the
T27337	2922-2927	CD	denotes	FOXP3
T27338	2928-2936	NN	denotes	promoter
T27339	2937-2945	NN	denotes	reporter
T27340	2946-2955	VB	denotes	construct
T27341	2956-2964	RB	denotes	together
T27342	2965-2969	IN	denotes	with
T27343	2970-2971	DT	denotes	a
T27344	2972-2977	JJ	denotes	GATA3
T27345	2978-2988	NN	denotes	expression
T27346	2989-2995	NN	denotes	vector
T27347	2996-2998	CC	denotes	or
T27348	2999-3001	DT	denotes	an
T27349	3002-3007	JJ	denotes	empty
T27350	3008-3014	NN	denotes	vector
T27351	3014-3015	.	denotes	.
T27352	3016-3020	NNS	denotes	Bars
T27353	3021-3025	VBP	denotes	show
T27354	3026-3029	DT	denotes	the
T27355	3030-3034	JJ	denotes	mean
T27356	3035-3036	NN	denotes	±
T27357	3037-3039	NNP	denotes	SD
T27358	3040-3042	IN	denotes	of
T27359	3043-3048	CD	denotes	three
T27360	3049-3060	JJ	denotes	independent
T27361	3061-3072	NNS	denotes	experiments
T27362	3072-3073	.	denotes	.
T27363	3074-3075	-LRB-	denotes	(
T27364	3075-3076	NNP	denotes	C
T27365	3076-3077	-RRB-	denotes	)
T27366	3078-3083	NNP	denotes	Naive
T27367	3084-3085	-LRB-	denotes	(
T27368	3085-3089	VBN	denotes	left
T27369	3090-3095	NN	denotes	panel
T27370	3095-3096	-RRB-	denotes	)
T27371	3097-3099	CC	denotes	or
T27372	3100-3106	NN	denotes	memory
T27373	3107-3108	-LRB-	denotes	(
T27374	3108-3113	JJ	denotes	right
T27375	3114-3119	NN	denotes	panel
T27376	3119-3120	-RRB-	denotes	)
T27377	3121-3124	CD	denotes	CD4
T27378	3125-3126	NNP	denotes	T
T27379	3127-3132	NNS	denotes	cells
T27380	3133-3137	VBD	denotes	were
T27381	3138-3149	VBN	denotes	transfected
T27382	3150-3154	IN	denotes	with
T27383	3155-3164	JJ	denotes	wild-type
T27384	3165-3167	CC	denotes	or
T27385	3168-3169	DT	denotes	a
T27386	3170-3175	NNP	denotes	GATA3
T27387	3176-3183	VBD	denotes	mutated
T27388	3184-3193	JJ	denotes	511-FOXP3
T27389	3194-3202	NN	denotes	promoter
T27390	3203-3211	NN	denotes	reporter
T27391	3212-3221	VB	denotes	construct
T27392	3222-3225	CC	denotes	and
T27393	3226-3235	VBN	denotes	activated
T27394	3236-3240	IN	denotes	with
T27395	3241-3244	NNP	denotes	PMA
T27396	3245-3248	CC	denotes	and
T27397	3249-3258	NN	denotes	ionomycin
T27398	3258-3259	.	denotes	.
T27399	3260-3264	NNS	denotes	Bars
T27400	3265-3269	VBP	denotes	show
T27401	3270-3273	DT	denotes	the
T27402	3274-3278	JJ	denotes	mean
T27403	3279-3280	NN	denotes	±
T27404	3281-3283	NNP	denotes	SD
T27405	3284-3286	IN	denotes	of
T27406	3287-3296	JJ	denotes	arbitrary
T27407	3297-3302	JJ	denotes	light
T27408	3303-3308	NNS	denotes	units
T27409	3309-3319	VBN	denotes	normalized
T27410	3320-3323	IN	denotes	for
T27411	3324-3331	NN	denotes	renilla
T27412	3332-3342	NN	denotes	luciferase
T27413	3343-3345	IN	denotes	of
T27414	3346-3351	CD	denotes	eight
T27415	3352-3363	JJ	denotes	independent
T27416	3364-3375	NNS	denotes	experiments
T27417	3375-3376	:	denotes	;
T27418	3377-3384	NNS	denotes	samples
T27419	3385-3389	VBD	denotes	were
T27420	3390-3398	VBN	denotes	measured
T27421	3399-3401	IN	denotes	in
T27422	3402-3413	NNS	denotes	triplicates
T27423	3413-3414	.	denotes	.
T27424	3415-3416	-LRB-	denotes	(
T27425	3416-3417	NNP	denotes	D
T27426	3417-3418	-RRB-	denotes	)
T27427	3419-3426	NNP	denotes	Nuclear
T27428	3427-3435	NNS	denotes	extracts
T27429	3436-3440	VBD	denotes	were
T27430	3441-3449	VBN	denotes	prepared
T27431	3450-3454	IN	denotes	from
T27432	3455-3458	NNP	denotes	HEK
T27433	3459-3464	NNS	denotes	cells
T27434	3465-3476	VBN	denotes	transfected
T27435	3477-3481	IN	denotes	with
T27436	3482-3487	CD	denotes	GATA3
T27437	3488-3490	CC	denotes	or
T27438	3491-3493	DT	denotes	an
T27439	3494-3499	JJ	denotes	empty
T27440	3500-3506	NN	denotes	vector
T27441	3506-3507	,	denotes	,
T27442	3508-3509	-LRB-	denotes	(
T27443	3509-3510	NNP	denotes	E
T27444	3510-3511	-RRB-	denotes	)
T27445	3512-3515	NNP	denotes	Th1
T27446	3515-3516	,	denotes	,
T27447	3517-3520	NNP	denotes	Th2
T27448	3520-3521	,	denotes	,
T27449	3522-3524	CC	denotes	or
T27450	3525-3530	NNP	denotes	iTreg
T27451	3531-3536	NNS	denotes	cells
T27452	3537-3540	CC	denotes	and
T27453	3541-3548	JJ	denotes	binding
T27454	3549-3556	NNS	denotes	factors
T27455	3557-3569	VBD	denotes	precipitated
T27456	3570-3575	VBG	denotes	using
T27457	3576-3588	JJ	denotes	biotinylated
T27458	3589-3605	NNS	denotes	oligonucleotides
T27459	3605-3606	.	denotes	.
T27460	3607-3610	DT	denotes	The
T27461	3611-3627	NNS	denotes	oligonucleotides
T27462	3628-3641	NN	denotes	transcription
T27463	3642-3648	NN	denotes	factor
T27475	3708-3713	NNP	denotes	GATA3
T27476	3714-3721	NN	denotes	protein
T27477	3722-3724	IN	denotes	in
T27478	3725-3728	DT	denotes	the
T27479	3729-3741	NNS	denotes	precipitates
T27480	3742-3746	VBD	denotes	were
T27481	3747-3755	VBN	denotes	assessed
T27482	3756-3758	IN	denotes	by
T27483	3759-3773	VBG	denotes	immunoblotting
T27484	3774-3778	IN	denotes	with
T27485	3779-3789	JJ	denotes	anti-GATA3
T27486	3790-3793	NNP	denotes	mAb
T27487	3793-3794	.	denotes	.
T27488	3795-3800	JJ	denotes	Total
T27489	3801-3808	JJ	denotes	nuclear
T27490	3809-3817	NNS	denotes	extracts
T27491	3818-3822	VBD	denotes	were
T27492	3823-3827	RB	denotes	also
T27493	3828-3831	VBN	denotes	run
T27494	3832-3834	IN	denotes	as
T27495	3835-3843	NNS	denotes	controls
T27496	3843-3844	.	denotes	.
T27497	3845-3849	NNS	denotes	Data
T27498	3850-3853	VBP	denotes	are
T27499	3854-3868	NN	denotes	representative
T27500	3869-3871	IN	denotes	of
T27501	3872-3877	CD	denotes	three
T27502	3878-3887	JJ	denotes	different
T27503	3888-3899	NNS	denotes	experiments
T27504	3899-3900	.	denotes	.
T27505	3901-3902	-LRB-	denotes	(
T27506	3902-3903	NN	denotes	F
T27507	3903-3904	-RRB-	denotes	)
T27508	3905-3910	NN	denotes	iTreg
T27509	3911-3913	CC	denotes	or
T27510	3914-3917	JJ	denotes	Th2
T27511	3918-3923	NNS	denotes	cells
T27512	3924-3928	VBD	denotes	were
T27513	3929-3937	VBN	denotes	analyzed
T27514	3938-3940	IN	denotes	by
T27515	3941-3945	NNP	denotes	ChIP
T27516	3946-3949	IN	denotes	for
T27517	3950-3955	NNP	denotes	GATA3
T27518	3956-3963	JJ	denotes	binding
T27519	3964-3966	TO	denotes	to
T27520	3967-3970	DT	denotes	the
T27521	3971-3976	CD	denotes	FOXP3
T27522	3977-3985	NN	denotes	promoter
T27523	3985-3986	.	denotes	.
T27524	3987-3990	DT	denotes	The
T27525	3992-3997	NN	denotes	input
T27526	3999-4009	VBZ	denotes	represents
T27527	4010-4013	NNP	denotes	PCR
T27528	4014-4027	NN	denotes	amplification
T27529	4028-4030	IN	denotes	of
T27530	4031-4034	DT	denotes	the
T27531	4035-4040	JJ	denotes	total
T27532	4041-4047	NN	denotes	sample
T27533	4047-4048	,	denotes	,
T27534	4049-4054	WDT	denotes	which
T27535	4055-4058	VBD	denotes	was
T27536	4059-4062	RB	denotes	not
T27537	4063-4072	VBN	denotes	subjected
T27538	4073-4075	TO	denotes	to
T27539	4076-4079	DT	denotes	any
T27540	4080-4093	NN	denotes	precipitation
T27541	4093-4094	.	denotes	.
T27542	4095-4102	NNS	denotes	Results
T27543	4103-4106	VBP	denotes	are
T27544	4107-4121	NN	denotes	representative
T27545	4122-4124	IN	denotes	of
T27546	4125-4130	CD	denotes	three
T27547	4131-4142	JJ	denotes	independent
T27548	4143-4154	NNS	denotes	experiments
T27549	4154-4155	.	denotes	.
T27464	3649-3658	NNS	denotes	complexes
T27465	3659-3663	VBD	denotes	were
T27466	3664-3673	VBN	denotes	separated
T27467	3674-3676	IN	denotes	on
T27468	3677-3678	DT	denotes	a
T27469	3679-3687	NNP	denotes	SDS-PAGE
T27470	3688-3691	NN	denotes	gel
T27471	3691-3692	.	denotes	.
T27472	3693-3696	DT	denotes	The
T27473	3697-3704	NNS	denotes	amounts
T27474	3705-3707	IN	denotes	of
R9042	T12080	T12081	nummod	GATA3,Represses
R9043	T12081	T12084	compound	Represses,Promoter
R9044	T12082	T12083	det	the,FOXP3
R9045	T12083	T12084	compound	FOXP3,Promoter
R9046	T12084	T12086	nsubj	Promoter,investigate
R9047	T12085	T12086	aux	To,investigate
R9048	T12086	T12086	ROOT	investigate,investigate
R9049	T12087	T12089	det	the,mechanism
R9050	T12088	T12089	amod	molecular,mechanism
R9051	T12089	T12086	dobj	mechanism,investigate
R9052	T12090	T12089	prep	of,mechanism
R9053	T12091	T12092	amod	GATA3-mediated,repression
R9054	T12092	T12090	pobj	repression,of
R9055	T12093	T12092	prep	of,repression
R9056	T12094	T12095	compound	human,FOXP3
R9057	T12095	T12093	pobj	FOXP3,of
R9058	T12096	T12102	punct	",",studied
R9059	T12097	T12100	det	the,promoter
R9060	T12098	T12100	amod	human,promoter
R9061	T12099	T12100	nummod	FOXP3,promoter
R9062	T12100	T12102	nsubjpass	promoter,studied
R9063	T12101	T12102	auxpass	was,studied
R9064	T12102	T12086	conj	studied,investigate
R9065	T12103	T12102	cc	and,studied
R9066	T12104	T12107	det	a,site
R9067	T12105	T12107	amod	palindromic,site
R9068	T12106	T12107	amod	binding,site
R9069	T12107	T12111	nsubjpass	site,discovered
R9070	T12108	T12107	prep	for,site
R9071	T12109	T12108	pobj	GATA3,for
R9072	T12110	T12111	auxpass	was,discovered
R9073	T12111	T12102	conj	discovered,studied
R9074	T12112	T12102	punct	.,studied
R9075	T12113	T12115	det	The,site
R9076	T12114	T12115	amod	GATA-binding,site
R9077	T12115	T12117	nsubjpass	site,located
R9078	T12116	T12117	auxpass	is,located
R9079	T12117	T12117	ROOT	located,located
R9080	T12118	T12120	nummod	303,upstream
R9081	T12119	T12120	compound	bp,upstream
R9082	T12120	T12117	advmod	upstream,located
R9083	T12121	T12120	prep	from,upstream
R9084	T12122	T12123	det	the,transcription
R9085	T12123	T12121	pobj	transcription,from
R9086	T12124	T12125	compound	start,site
R9087	T12125	T12131	nmod	site,]
R9088	T12126	T12127	punct	(,TSS
R9089	T12127	T12125	appos	TSS,site
R9090	T12128	T12125	punct	),site
R9091	T12129	T12131	nmod	[,]
R9092	T12130	T12131	nummod	24,]
R9093	T12131	T12117	npadvmod	],located
R9094	T12132	T12117	punct	.,located
R9095	T12133	T12134	det	This,site
R9096	T12134	T12137	nsubjpass	site,conserved
R9097	T12135	T12137	auxpass	is,conserved
R9098	T12136	T12137	advmod	highly,conserved
R9099	T12137	T12137	ROOT	conserved,conserved
R9100	T12138	T12137	prep	between,conserved
R9101	T12139	T12138	pobj	humans,between
R9102	T12140	T12139	punct	",",humans
R9103	T12141	T12139	conj	mice,humans
R9104	T12142	T12137	punct	",",conserved
R9105	T12143	T12137	cc	and,conserved
R9106	T12144	T12137	conj	rats,conserved
R9107	T12145	T12146	punct	(,Figure
R9108	T12146	T12144	appos	Figure,rats
R9109	T12147	T12146	nummod	S4,Figure
R9110	T12148	T12144	punct	),rats
R9111	T12149	T12137	cc	and,conserved
R9112	T12150	T12152	aux	may,play
R9113	T12151	T12152	advmod	therefore,play
R9114	T12152	T12137	conj	play,conserved
R9115	T12153	T12155	det	an,role
R9116	T12154	T12155	amod	important,role
R9117	T12155	T12152	dobj	role,play
R9118	T12156	T12152	prep	in,play
R9119	T12157	T12158	amod	FOXP3,regulation
R9120	T12158	T12156	pobj	regulation,in
R9121	T12159	T12137	punct	.,conserved
R9122	T12160	T12162	det	The,relevance
R9123	T12161	T12162	amod	functional,relevance
R9124	T12162	T12167	nsubjpass	relevance,studied
R9125	T12163	T12162	prep	of,relevance
R9126	T12164	T12165	det	this,site
R9127	T12165	T12163	pobj	site,of
R9128	T12166	T12167	auxpass	was,studied
R9129	T12167	T12167	ROOT	studied,studied
R9130	T12168	T12167	advcl	using,studied
R9131	T12169	T12170	det	a,FOXP3-promoter
R9132	T12170	T12171	nsubj	FOXP3-promoter,construct
R9133	T12171	T12168	xcomp	construct,using
R9134	T12172	T12174	nmod	[,]
R9135	T12173	T12174	nummod	24,]
R9136	T12174	T12171	dobj	],construct
R9137	T12175	T12167	punct	.,studied
R9138	T12176	T12177	nsubj	We,transfected
R9139	T12177	T12177	ROOT	transfected,transfected
R9140	T12178	T12183	amod	human,cells
R9141	T12179	T12183	amod	primary,cells
R9142	T12180	T12183	compound	CD4,cells
R9143	T12181	T12183	nummod	+,cells
R9144	T12182	T12183	compound	T,cells
R9145	T12183	T12177	dobj	cells,transfected
R9146	T12184	T12177	punct	",",transfected
R9147	T12185	T12177	prep	in,transfected
R9148	T12186	T12189	amod	vitro,cells
R9149	T12187	T12189	amod	differentiated,cells
R9150	T12188	T12189	amod	Th2,cells
R9151	T12189	T12185	pobj	cells,in
R9152	T12190	T12177	punct	",",transfected
R9153	T12191	T12177	cc	and,transfected
R9154	T12192	T12193	compound	Jurkat,cells
R9155	T12193	T12177	conj	cells,transfected
R9156	T12194	T12198	punct	(,known
R9157	T12195	T12196	compound	Jurkat,cells
R9158	T12196	T12198	nsubjpass	cells,known
R9159	T12197	T12198	auxpass	are,known
R9160	T12198	T12193	relcl	known,cells
R9161	T12199	T12201	aux	to,express
R9162	T12200	T12201	advmod	constitutively,express
R9163	T12201	T12198	xcomp	express,known
R9164	T12202	T12203	compound	GATA3,[
R9165	T12203	T12201	dobj	[,express
R9166	T12204	T12205	nummod	"25,26",]
R9167	T12205	T12203	appos	],[
R9168	T12206	T12203	punct	),[
R9169	T12207	T12198	punct	",",known
R9170	T12208	T12177	cc	and,transfected
R9171	T12209	T12210	nsubj	we,measured
R9172	T12210	T12177	conj	measured,transfected
R9173	T12211	T12213	nummod	FOXP3,activity
R9174	T12212	T12213	compound	promoter,activity
R9175	T12213	T12210	dobj	activity,measured
R9176	T12214	T12210	punct	.,measured
R9177	T12215	T12216	det	The,promoter
R9178	T12216	T12217	nsubj	promoter,was
R9179	T12217	T12217	ROOT	was,was
R9180	T12218	T12217	neg	not,was
R9181	T12219	T12217	acomp	active,was
R9182	T12220	T12219	prep	in,active
R9183	T12221	T12224	det	the,line
R9184	T12222	T12223	compound	GATA3-expressing,cell
R9185	T12223	T12224	compound	cell,line
R9186	T12224	T12220	pobj	line,in
R9187	T12225	T12224	appos	Jurkat,line
R9188	T12226	T12220	cc	or,in
R9189	T12227	T12220	conj	in,in
R9190	T12228	T12229	det	the,in
R9191	T12229	T12227	pobj	in,in
R9192	T12230	T12232	amod	vitro-differentiated,cells
R9193	T12231	T12232	amod	Th2,cells
R9194	T12232	T12229	pobj	cells,in
R9195	T12233	T12217	punct	",",was
R9196	T12234	T12237	mark	whereas,was
R9197	T12235	T12236	det	the,construct
R9198	T12236	T12237	nsubj	construct,was
R9199	T12237	T12217	advcl	was,was
R9200	T12238	T12237	acomp	active,was
R9201	T12239	T12238	prep	in,active
R9202	T12240	T12242	det	the,cells
R9203	T12241	T12242	compound	CD4,cells
R9204	T12242	T12239	pobj	cells,in
R9205	T12243	T12237	punct	",",was
R9206	T12244	T12245	nsubj	which,express
R9207	T12245	T12217	conj	express,was
R9208	T12246	T12248	det	a,amount
R9209	T12247	T12248	amod	lower,amount
R9210	T12248	T12245	dobj	amount,express
R9211	T12249	T12248	prep	of,amount
R9212	T12250	T12249	pobj	GATA3,of
R9213	T12251	T12253	punct	(,8A
R9214	T12252	T12253	compound	Figure,8A
R9215	T12253	T12250	appos	8A,GATA3
R9216	T12254	T12253	punct	),8A
R9217	T12255	T12217	punct	.,was
R9218	T12256	T12263	nsubj	Overexpression,diminished
R9219	T12257	T12256	prep	of,Overexpression
R9220	T12258	T12257	pobj	GATA3,of
R9221	T12259	T12256	prep	in,Overexpression
R9222	T12260	T12262	amod	naive,cells
R9223	T12261	T12262	compound	T,cells
R9224	T12262	T12259	pobj	cells,in
R9225	T12263	T12263	ROOT	diminished,diminished
R9226	T12264	T12265	compound	luciferase,activity
R9227	T12265	T12263	dobj	activity,diminished
R9228	T12266	T12265	prep	of,activity
R9229	T12267	T12269	det	the,promoter
R9230	T12268	T12269	nummod	FOXP3,promoter
R9231	T12269	T12266	pobj	promoter,of
R9232	T12270	T12263	prep	compared,diminished
R9233	T12271	T12270	prep	with,compared
R9234	T12272	T12274	det	the,vector
R9235	T12273	T12274	compound	control,vector
R9236	T12274	T12271	pobj	vector,with
R9237	T12275	T12277	punct	(,8B
R9238	T12276	T12277	compound	Figure,8B
R9239	T12277	T12274	appos	8B,vector
R9240	T12278	T12277	punct	),8B
R9241	T12279	T12263	punct	.,diminished
R9242	T12280	T12282	aux	To,address
R9243	T12281	T12282	advmod	further,address
R9244	T12282	T12291	advcl	address,inserted
R9245	T12283	T12284	det	the,function
R9246	T12284	T12282	dobj	function,address
R9247	T12285	T12284	prep	of,function
R9248	T12286	T12288	det	the,site
R9249	T12287	T12288	compound	GATA3,site
R9250	T12288	T12285	pobj	site,of
R9251	T12289	T12291	punct	",",inserted
R9252	T12290	T12291	nsubj	we,inserted
R9253	T12291	T12291	ROOT	inserted,inserted
R9254	T12292	T12294	det	a,mutation
R9255	T12293	T12294	amod	site-specific,mutation
R9256	T12294	T12291	dobj	mutation,inserted
R9257	T12295	T12294	acl	deleting,mutation
R9258	T12296	T12298	det	the,site
R9259	T12297	T12298	amod	GATA3-binding,site
R9260	T12298	T12295	dobj	site,deleting
R9261	T12299	T12291	punct	.,inserted
R9262	T12300	T12301	det	This,mutation
R9263	T12301	T12302	nsubj	mutation,increased
R9264	T12302	T12302	ROOT	increased,increased
R9265	T12303	T12304	compound	luciferase,activity
R9266	T12304	T12302	dobj	activity,increased
R9267	T12305	T12304	prep	by,activity
R9268	T12306	T12305	pobj	3-fold,by
R9269	T12307	T12306	prep	in,3-fold
R9270	T12308	T12307	pobj	memory,in
R9271	T12309	T12311	compound	CD4,CD45RO
R9272	T12310	T12311	compound	+,CD45RO
R9273	T12311	T12312	nsubj	CD45RO,+
R9274	T12312	T12302	conj	+,increased
R9275	T12313	T12314	compound	T,cells
R9276	T12314	T12312	dobj	cells,+
R9277	T12315	T12312	punct	",",+
R9278	T12316	T12320	mark	whereas,observed
R9279	T12317	T12318	det	no,difference
R9280	T12318	T12320	nsubjpass	difference,observed
R9281	T12319	T12320	auxpass	was,observed
R9282	T12320	T12312	advcl	observed,+
R9283	T12321	T12320	prep	in,observed
R9284	T12322	T12331	amod	naive,cells
R9285	T12323	T12331	punct	(,cells
R9286	T12324	T12331	nummod	GATA3,cells
R9287	T12325	T12324	punct	),GATA3
R9288	T12326	T12331	nummod	CD4,cells
R9289	T12327	T12331	nummod	+,cells
R9290	T12328	T12331	nmod	CD45RA,cells
R9291	T12329	T12331	nummod	+,cells
R9292	T12330	T12331	compound	T,cells
R9293	T12331	T12321	pobj	cells,in
R9294	T12332	T12320	punct	",",observed
R9295	T12333	T12320	advcl	revealing,observed
R9296	T12334	T12336	det	a,activity
R9297	T12335	T12336	compound	repressor,activity
R9298	T12336	T12333	dobj	activity,revealing
R9299	T12337	T12336	prep	of,activity
R9300	T12338	T12337	pobj	GATA3,of
R9301	T12339	T12333	prep	on,revealing
R9302	T12340	T12342	det	the,promoter
R9303	T12341	T12342	nummod	FOXP3,promoter
R9304	T12342	T12339	pobj	promoter,on
R9305	T12343	T12345	punct	(,8C
R9306	T12344	T12345	compound	Figure,8C
R9307	T12345	T12342	appos	8C,promoter
R9308	T12346	T12345	punct	),8C
R9309	T12347	T12302	punct	.,increased
R9310	T12348	T12350	advmod	Furthermore,binds
R9311	T12349	T12350	amod	GATA3,binds
R9312	T12350	T12350	ROOT	binds,binds
R9313	T12351	T12352	advmod	directly,to
R9314	T12352	T12350	prep	to,binds
R9315	T12353	T12355	det	the,promoter
R9316	T12354	T12355	nummod	FOXP3,promoter
R9317	T12355	T12352	pobj	promoter,to
R9318	T12356	T12357	mark	as,investigated
R9319	T12357	T12350	advcl	investigated,binds
R9320	T12358	T12357	agent	by,investigated
R9321	T12359	T12360	amod	pull-down,assay
R9322	T12360	T12358	pobj	assay,by
R9323	T12361	T12350	punct	.,binds
R9324	T12362	T12363	compound	HEK,cells
R9325	T12363	T12366	nsubjpass	cells,transfected
R9326	T12364	T12366	auxpass	were,transfected
R9327	T12365	T12366	advmod	transiently,transfected
R9328	T12366	T12366	ROOT	transfected,transfected
R9329	T12367	T12380	mark	with,incubated
R9330	T12368	T12380	nsubjpass	GATA3,incubated
R9331	T12369	T12368	cc	or,GATA3
R9332	T12370	T12372	det	a,vector
R9333	T12371	T12372	compound	control,vector
R9334	T12372	T12368	conj	vector,GATA3
R9335	T12373	T12372	punct	",",vector
R9336	T12374	T12372	cc	and,vector
R9337	T12375	T12372	conj	increasing,vector
R9338	T12376	T12375	dobj	amounts,increasing
R9339	T12377	T12376	prep	of,amounts
R9340	T12378	T12377	pobj	lysates,of
R9341	T12379	T12380	auxpass	were,incubated
R9342	T12380	T12366	advcl	incubated,transfected
R9343	T12381	T12380	prep	with,incubated
R9344	T12382	T12381	pobj	oligonucleotides,with
R9345	T12383	T12382	acl	containing,oligonucleotides
R9346	T12384	T12386	det	the,site
R9347	T12385	T12386	compound	GATA3,site
R9348	T12386	T12383	dobj	site,containing
R9349	T12387	T12386	prep	of,site
R9350	T12388	T12390	det	the,promoter
R9351	T12389	T12390	nummod	FOXP3,promoter
R9352	T12390	T12387	pobj	promoter,of
R9353	T12391	T12390	cc	or,promoter
R9354	T12392	T12394	det	a,oligonucleotide
R9355	T12393	T12394	compound	control,oligonucleotide
R9356	T12394	T12390	conj	oligonucleotide,promoter
R9357	T12395	T12394	prep	with,oligonucleotide
R9358	T12396	T12399	det	a,site
R9359	T12397	T12399	amod	mutated,site
R9360	T12398	T12399	amod	GATA3-binding,site
R9361	T12399	T12395	pobj	site,with
R9362	T12400	T12366	punct	.,transfected
R9363	T12401	T12408	mark	After,detected
R9364	T12402	T12408	det	the,detected
R9365	T12403	T12408	amod	pull-down,detected
R9366	T12404	T12408	punct	",",detected
R9367	T12405	T12406	amod	GATA3,binding
R9368	T12406	T12408	nsubjpass	binding,detected
R9369	T12407	T12408	auxpass	was,detected
R9370	T12408	T12408	ROOT	detected,detected
R9371	T12409	T12408	agent	by,detected
R9372	T12410	T12411	amod	Western,blot
R9373	T12411	T12409	pobj	blot,by
R9374	T12412	T12408	punct	.,detected
R9375	T12413	T12422	advmod	Similarly,subjected
R9376	T12414	T12422	punct	",",subjected
R9377	T12415	T12417	amod	GATA3-expressing,cells
R9378	T12416	T12417	amod	Th2,cells
R9379	T12417	T12422	nsubjpass	cells,subjected
R9380	T12418	T12417	cc	and,cells
R9381	T12419	T12420	compound	iTreg,cells
R9382	T12420	T12417	conj	cells,cells
R9383	T12421	T12422	auxpass	were,subjected
R9384	T12422	T12422	ROOT	subjected,subjected
R9385	T12423	T12422	prep	to,subjected
R9386	T12424	T12425	det	this,approach
R9387	T12425	T12423	pobj	approach,to
R9388	T12426	T12422	punct	.,subjected
R9389	T12427	T12428	advmod	Only,HEK
R9390	T12428	T12429	compound	HEK,cells
R9391	T12429	T12435	nsubj	cells,showed
R9392	T12430	T12429	acl	overexpressing,cells
R9393	T12431	T12434	nmod	GATA3,cells
R9394	T12432	T12431	cc	and,GATA3
R9395	T12433	T12431	conj	Th2,GATA3
R9396	T12434	T12430	dobj	cells,overexpressing
R9397	T12435	T12435	ROOT	showed,showed
R9398	T12436	T12437	amod	GATA3-binding,activity
R9399	T12437	T12435	dobj	activity,showed
R9400	T12438	T12439	punct	(,Figure
R9401	T12439	T12437	appos	Figure,activity
R9402	T12440	T12439	nummod	8D,Figure
R9403	T12441	T12439	cc	and,Figure
R9404	T12442	T12439	conj	8E,Figure
R9405	T12443	T12437	punct	),activity
R9406	T12444	T12435	punct	.,showed
R9407	T12445	T12446	det	These,experiments
R9408	T12446	T12447	nsubj	experiments,demonstrated
R9409	T12447	T12447	ROOT	demonstrated,demonstrated
R9410	T12448	T12450	mark	that,binds
R9411	T12449	T12450	nsubj	GATA3,binds
R9412	T12450	T12447	ccomp	binds,demonstrated
R9413	T12451	T12454	det	the,promoter
R9414	T12452	T12454	amod	palindromic,promoter
R9415	T12453	T12454	nummod	FOXP3,promoter
R9416	T12454	T12450	dobj	promoter,binds
R9417	T12455	T12447	punct	.,demonstrated
R9418	T12456	T12457	aux	To,gain
R9419	T12457	T12466	advcl	gain,performed
R9420	T12458	T12457	dobj	insights,gain
R9421	T12459	T12458	prep	into,insights
R9422	T12460	T12466	dep	the,performed
R9423	T12461	T12466	prep	in,performed
R9424	T12462	T12463	compound	vivo,situation
R9425	T12463	T12461	pobj	situation,in
R9426	T12464	T12466	punct	",",performed
R9427	T12465	T12466	nsubj	we,performed
R9428	T12466	T12466	ROOT	performed,performed
R9429	T12467	T12469	det	a,immunoprecipitation
R9430	T12468	T12469	compound	chromatin,immunoprecipitation
R9431	T12469	T12466	dobj	immunoprecipitation,performed
R9432	T12470	T12469	punct	(,immunoprecipitation
R9433	T12471	T12469	appos	ChIP,immunoprecipitation
R9434	T12472	T12469	punct	),immunoprecipitation
R9435	T12473	T12466	advcl	using,performed
R9436	T12474	T12476	det	an,antibody
R9437	T12475	T12476	amod	anti-GATA3,antibody
R9438	T12476	T12473	dobj	antibody,using
R9439	T12477	T12466	cc	and,performed
R9440	T12478	T12466	conj	showed,performed
R9441	T12479	T12478	dobj	that,showed
R9442	T12480	T12481	nummod	GATA3,binds
R9443	T12481	T12479	nsubj	binds,that
R9444	T12482	T12481	prep	to,binds
R9445	T12483	T12486	det	the,region
R9446	T12484	T12486	nummod	FOXP3,region
R9447	T12485	T12486	compound	promoter,region
R9448	T12486	T12482	pobj	region,to
R9449	T12487	T12481	prep	in,binds
R9450	T12488	T12489	amod	Th2,cells
R9451	T12489	T12487	pobj	cells,in
R9452	T12490	T12481	punct	",",binds
R9453	T12491	T12481	cc	but,binds
R9454	T12492	T12493	neg	not,in
R9455	T12493	T12497	prep	in,Figure
R9456	T12494	T12495	compound	iTreg,cells
R9457	T12495	T12493	pobj	cells,in
R9458	T12496	T12497	punct	(,Figure
R9459	T12497	T12481	appos	Figure,binds
R9460	T12498	T12497	nummod	7F,Figure
R9461	T12499	T12497	punct	),Figure
R9462	T12500	T12466	punct	.,performed
R9463	T12501	T12505	advcl	Taken,demonstrate
R9464	T12502	T12501	advmod	together,Taken
R9465	T12503	T12504	det	these,data
R9466	T12504	T12505	nsubj	data,demonstrate
R9467	T12505	T12505	ROOT	demonstrate,demonstrate
R9468	T12506	T12514	mark	that,repressing
R9469	T12507	T12508	det	the,GATA3-binding
R9470	T12508	T12514	nsubj	GATA3-binding,repressing
R9471	T12509	T12508	prep	to,GATA3-binding
R9472	T12510	T12512	det	the,promoter
R9473	T12511	T12512	nummod	FOXP3,promoter
R9474	T12512	T12509	pobj	promoter,to
R9475	T12513	T12514	aux	is,repressing
R9476	T12514	T12505	ccomp	repressing,demonstrate
R9477	T12515	T12516	nummod	FOXP3,expression
R9478	T12516	T12514	dobj	expression,repressing
R9479	T12517	T12505	punct	.,demonstrate
R20134	T27290	T27293	amod	putative,region
R20135	T27291	T27293	nummod	FOXP3,region
R20136	T27292	T27293	compound	promoter,region
R20137	T27293	T27288	dobj	region,containing
R20138	T27294	T27276	conj	fused,transfected
R20139	T27295	T27294	prep	to,fused
R20140	T27296	T27299	det	the,gene
R20141	T27297	T27299	amod	luciferase,gene
R20142	T27298	T27299	compound	reporter,gene
R20143	T27299	T27295	pobj	gene,to
R20144	T27300	T27276	punct	.,transfected
R20145	T27301	T27302	nsubj	Bars,show
R20146	T27302	T27302	ROOT	show,show
R20147	T27303	T27306	det	the,SD
R20148	T27304	T27306	amod	mean,SD
R20149	T27305	T27306	compound	±,SD
R20150	T27306	T27302	dobj	SD,show
R20151	T27307	T27306	prep	of,SD
R20152	T27308	T27310	amod	arbitrary,units
R20153	T27309	T27310	amod	light,units
R20154	T27310	T27307	pobj	units,of
R20155	T27311	T27310	acl	normalized,units
R20156	T27312	T27311	prep	for,normalized
R20157	T27313	T27314	compound	renilla,luciferase
R20158	T27314	T27312	pobj	luciferase,for
R20159	T27315	T27314	prep	of,luciferase
R20160	T27316	T27318	nummod	four,experiments
R20161	T27317	T27318	amod	independent,experiments
R20162	T27318	T27315	pobj	experiments,of
R20163	T27319	T27322	punct	;,measured
R20164	T27320	T27322	nsubjpass	samples,measured
R20165	T27321	T27322	auxpass	were,measured
R20166	T27322	T27302	ccomp	measured,show
R20167	T27323	T27322	prep	in,measured
R20168	T27324	T27323	pobj	triplicates,in
R20169	T27325	T27302	punct	.,show
R20170	T27326	T27327	punct	(,B
R20171	T27327	T27327	ROOT	B,B
R20172	T27328	T27327	punct	),B
R20173	T27329	T27332	compound	Naive,cells
R20174	T27330	T27331	compound	CD4,T
R20175	T27331	T27332	compound	T,cells
R20176	T27332	T27334	nsubjpass	cells,transfected
R20177	T27333	T27334	auxpass	were,transfected
R20201	T27357	T27353	dobj	SD,show
R20202	T27358	T27357	prep	of,SD
R20203	T27359	T27361	nummod	three,experiments
R20204	T27360	T27361	amod	independent,experiments
R20205	T27361	T27358	pobj	experiments,of
R20206	T27362	T27353	punct	.,show
R20207	T27363	T27366	punct	(,Naive
R20208	T27364	T27366	nmod	C,Naive
R20209	T27365	T27366	punct	),Naive
R20210	T27366	T27381	nsubjpass	Naive,transfected
R20211	T27367	T27368	punct	(,left
R20212	T27368	T27369	amod	left,panel
R20213	T27369	T27366	appos	panel,Naive
R20214	T27370	T27369	punct	),panel
R20215	T27371	T27369	cc	or,panel
R20216	T27372	T27369	conj	memory,panel
R20217	T27373	T27375	punct	(,panel
R20218	T27374	T27375	amod	right,panel
R20219	T27375	T27369	appos	panel,panel
R20220	T27376	T27369	punct	),panel
R20221	T27377	T27379	nummod	CD4,cells
R20222	T27378	T27379	compound	T,cells
R20223	T27379	T27381	nsubjpass	cells,transfected
R20224	T27380	T27381	auxpass	were,transfected
R20225	T27381	T27381	ROOT	transfected,transfected
R20226	T27382	T27381	prep	with,transfected
R20227	T27383	T27382	pobj	wild-type,with
R20228	T27384	T27383	cc	or,wild-type
R20229	T27385	T27386	det	a,GATA3
R20230	T27386	T27387	nsubj	GATA3,mutated
R20231	T27387	T27387	ROOT	mutated,mutated
R20232	T27388	T27390	amod	511-FOXP3,reporter
R20233	T27389	T27390	compound	promoter,reporter
R20234	T27390	T27391	compound	reporter,construct
R20235	T27391	T27387	dobj	construct,mutated
R20236	T27392	T27387	cc	and,mutated
R20237	T27393	T27387	conj	activated,mutated
R20238	T27394	T27393	prep	with,activated
R20239	T27395	T27394	pobj	PMA,with
R20240	T27396	T27395	cc	and,PMA
R20241	T27397	T27395	conj	ionomycin,PMA
R20242	T27398	T27387	punct	.,mutated
R20243	T27399	T27400	nsubj	Bars,show
R20244	T27400	T27400	ROOT	show,show
R20245	T27401	T27404	det	the,SD
R20246	T27402	T27404	amod	mean,SD
R20247	T27403	T27404	compound	±,SD
R20248	T27404	T27400	dobj	SD,show
R20249	T27405	T27404	prep	of,SD
R20250	T27406	T27408	amod	arbitrary,units
R20251	T27407	T27408	amod	light,units
R20252	T27408	T27405	pobj	units,of
R20253	T27409	T27408	acl	normalized,units
R20254	T27410	T27409	prep	for,normalized
R20255	T27411	T27412	compound	renilla,luciferase
R20256	T27412	T27410	pobj	luciferase,for
R20257	T27413	T27412	prep	of,luciferase
R20258	T27414	T27416	nummod	eight,experiments
R20259	T27415	T27416	amod	independent,experiments
R20260	T27416	T27413	pobj	experiments,of
R20261	T27417	T27420	punct	;,measured
R20262	T27418	T27420	nsubjpass	samples,measured
R20263	T27419	T27420	auxpass	were,measured
R20264	T27420	T27400	ccomp	measured,show
R20265	T27421	T27420	prep	in,measured
R20266	T27422	T27421	pobj	triplicates,in
R20267	T27423	T27400	punct	.,show
R20268	T27424	T27425	punct	(,D
R20269	T27425	T27425	ROOT	D,D
R20270	T27426	T27425	punct	),D
R20271	T27427	T27428	compound	Nuclear,extracts
R20272	T27428	T27430	nsubjpass	extracts,prepared
R20273	T27429	T27430	auxpass	were,prepared
R20274	T27430	T27430	ROOT	prepared,prepared
R20275	T27431	T27430	prep	from,prepared
R20276	T27432	T27433	compound	HEK,cells
R20277	T27433	T27431	pobj	cells,from
R20278	T27434	T27430	conj	transfected,prepared
R20279	T27435	T27434	prep	with,transfected
R20280	T27436	T27451	nummod	GATA3,cells
R20281	T27437	T27436	cc	or,GATA3
R20282	T27438	T27440	det	an,vector
R20283	T27439	T27440	amod	empty,vector
R20284	T27440	T27436	conj	vector,GATA3
R20285	T27441	T27436	punct	",",GATA3
R20286	T27442	T27445	punct	(,Th1
R20287	T27443	T27445	nmod	E,Th1
R20288	T27444	T27445	punct	),Th1
R20289	T27445	T27451	nmod	Th1,cells
R20290	T27446	T27445	punct	",",Th1
R20291	T27447	T27445	conj	Th2,Th1
R20292	T27448	T27447	punct	",",Th2
R20293	T27449	T27447	cc	or,Th2
R20294	T27450	T27447	conj	iTreg,Th2
R20295	T27451	T27435	pobj	cells,with
R20296	T27452	T27451	cc	and,cells
R20297	T27453	T27454	amod	binding,factors
R20298	T27454	T27451	conj	factors,cells
R20299	T27455	T27430	conj	precipitated,prepared
R20300	T27456	T27455	xcomp	using,precipitated
R20301	T27457	T27458	amod	biotinylated,oligonucleotides
R20302	T27458	T27456	dobj	oligonucleotides,using
R20303	T27459	T27430	punct	.,prepared
R20304	T27460	T27461	det	The,oligonucleotides
R20305	T27461	T27466	nsubjpass	oligonucleotides,separated
R20306	T27462	T27463	compound	transcription,factor
R20307	T27463	T27464	compound	factor,complexes
R20308	T27464	T27466	nsubjpass	complexes,separated
R20309	T27465	T27466	auxpass	were,separated
R20310	T27466	T27466	ROOT	separated,separated
R20311	T27467	T27466	prep	on,separated
R20312	T27468	T27470	det	a,gel
R20313	T27469	T27470	compound	SDS-PAGE,gel
R20314	T27470	T27467	pobj	gel,on
R20315	T27471	T27466	punct	.,separated
R20316	T27472	T27473	det	The,amounts
R20317	T27473	T27481	nsubjpass	amounts,assessed
R20318	T27474	T27473	prep	of,amounts
R20319	T27475	T27476	compound	GATA3,protein
R20320	T27476	T27474	pobj	protein,of
R20321	T27477	T27473	prep	in,amounts
R20322	T27478	T27479	det	the,precipitates
R20323	T27479	T27477	pobj	precipitates,in
R20324	T27480	T27481	auxpass	were,assessed
R20325	T27481	T27481	ROOT	assessed,assessed
R20326	T27482	T27481	agent	by,assessed
R20327	T27483	T27482	pcomp	immunoblotting,by
R20328	T27484	T27483	prep	with,immunoblotting
R20329	T27485	T27486	compound	anti-GATA3,mAb
R20330	T27486	T27484	pobj	mAb,with
R20331	T27487	T27481	punct	.,assessed
R20332	T27488	T27490	amod	Total,extracts
R20333	T27489	T27490	amod	nuclear,extracts
R20334	T27490	T27493	nsubjpass	extracts,run
R20335	T27491	T27493	auxpass	were,run
R20336	T27492	T27493	advmod	also,run
R20337	T27493	T27493	ROOT	run,run
R20338	T27494	T27493	prep	as,run
R20339	T27495	T27494	pobj	controls,as
R20340	T27496	T27493	punct	.,run
R20341	T27497	T27498	nsubj	Data,are
R20342	T27498	T27498	ROOT	are,are
R20343	T27499	T27498	attr	representative,are
R20344	T27500	T27499	prep	of,representative
R20345	T27501	T27503	nummod	three,experiments
R20346	T27502	T27503	amod	different,experiments
R20347	T27503	T27500	pobj	experiments,of
R20348	T27504	T27498	punct	.,are
R20349	T27505	T27513	punct	(,analyzed
R20350	T27506	T27508	nmod	F,iTreg
R20351	T27507	T27506	punct	),F
R20352	T27508	T27513	nsubjpass	iTreg,analyzed
R20353	T27509	T27508	cc	or,iTreg
R20354	T27510	T27511	amod	Th2,cells
R20355	T27511	T27508	conj	cells,iTreg
R20356	T27512	T27513	auxpass	were,analyzed
R20357	T27513	T27513	ROOT	analyzed,analyzed
R20358	T27514	T27513	agent	by,analyzed
R20359	T27515	T27514	pobj	ChIP,by
R20360	T27516	T27513	prep	for,analyzed
R20361	T27517	T27516	pobj	GATA3,for
R20362	T27518	T27513	oprd	binding,analyzed
R20363	T27519	T27518	prep	to,binding
R20364	T27520	T27522	det	the,promoter
R20365	T27521	T27522	nummod	FOXP3,promoter
R20386	T27542	T27543	nsubj	Results,are
R20387	T27543	T27543	ROOT	are,are
R20388	T27544	T27543	attr	representative,are
R20389	T27545	T27544	prep	of,representative
R20390	T27546	T27548	nummod	three,experiments
R20391	T27547	T27548	amod	independent,experiments
R20392	T27548	T27545	pobj	experiments,of
R20393	T27549	T27543	punct	.,are
R20131	T27287	T27280	conj	vector,vector
R20132	T27288	T27287	acl	containing,vector
R20133	T27289	T27293	det	the,region
R20178	T27334	T27334	ROOT	transfected,transfected
R20179	T27335	T27334	prep	with,transfected
R20180	T27336	T27339	det	the,reporter
R20181	T27337	T27339	nummod	FOXP3,reporter
R20182	T27338	T27339	compound	promoter,reporter
R20183	T27339	T27335	pobj	reporter,with
R20184	T27340	T27334	advcl	construct,transfected
R20185	T27341	T27340	advmod	together,construct
R20186	T27342	T27340	prep	with,construct
R20187	T27343	T27346	det	a,vector
R20188	T27344	T27346	amod	GATA3,vector
R20189	T27345	T27346	compound	expression,vector
R20190	T27346	T27342	pobj	vector,with
R20191	T27347	T27346	cc	or,vector
R20192	T27348	T27350	det	an,vector
R20193	T27349	T27350	amod	empty,vector
R20194	T27350	T27346	conj	vector,vector
R20195	T27351	T27334	punct	.,transfected
R20196	T27352	T27353	nsubj	Bars,show
R20197	T27353	T27353	ROOT	show,show
R20198	T27354	T27357	det	the,SD
R20199	T27355	T27357	amod	mean,SD
R20200	T27356	T27357	compound	±,SD
R20100	T27256	T27257	nummod	GATA3,Represses
R20101	T27257	T27265	nmod	Represses,Jurkat
R20102	T27258	T27260	det	the,FOXP3
R20103	T27259	T27260	compound	Human,FOXP3
R20104	T27260	T27265	nmod	FOXP3,Jurkat
R20105	T27261	T27265	nmod	Promoter,Jurkat
R20106	T27262	T27263	punct	(,A
R20107	T27263	T27261	ccomp	A,Promoter
R20108	T27264	T27265	punct	),Jurkat
R20109	T27265	T27268	nmod	Jurkat,cells
R20110	T27266	T27265	punct	",",Jurkat
R20111	T27267	T27268	compound	Th2,cells
R20112	T27268	T27276	nsubjpass	cells,transfected
R20113	T27269	T27268	punct	",",cells
R20114	T27270	T27268	cc	and,cells
R20115	T27271	T27274	amod	human,cells
R20116	T27272	T27274	amod	primary,cells
R20117	T27273	T27274	compound	CD4,cells
R20118	T27274	T27268	conj	cells,cells
R20119	T27275	T27276	auxpass	were,transfected
R20120	T27276	T27276	ROOT	transfected,transfected
R20121	T27277	T27276	prep	with,transfected
R20122	T27278	T27280	det	an,vector
R20123	T27279	T27280	amod	empty,vector
R20124	T27280	T27277	pobj	vector,with
R20125	T27281	T27283	punct	(,basic
R20126	T27282	T27283	compound	pGL3,basic
R20127	T27283	T27280	appos	basic,vector
R20128	T27284	T27283	punct	),basic
R20129	T27285	T27280	cc	or,vector
R20130	T27286	T27287	det	a,vector
R20366	T27522	T27519	pobj	promoter,to
R20367	T27523	T27513	punct	.,analyzed
R20368	T27524	T27526	dobj	The,represents
R20369	T27525	T27526	nsubj	input,represents
R20370	T27526	T27526	ROOT	represents,represents
R20371	T27527	T27528	compound	PCR,amplification
R20372	T27528	T27526	dobj	amplification,represents
R20373	T27529	T27528	prep	of,amplification
R20374	T27530	T27532	det	the,sample
R20375	T27531	T27532	amod	total,sample
R20376	T27532	T27529	pobj	sample,of
R20377	T27533	T27532	punct	",",sample
R20378	T27534	T27537	nsubjpass	which,subjected
R20379	T27535	T27537	auxpass	was,subjected
R20380	T27536	T27537	neg	not,subjected
R20381	T27537	T27532	relcl	subjected,sample
R20382	T27538	T27537	prep	to,subjected
R20383	T27539	T27540	det	any,precipitation
R20384	T27540	T27538	pobj	precipitation,to
R20385	T27541	T27526	punct	.,represents

GO-BP

Id	Subject	Object	Predicate	Lexical cue
T11586	271-284	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T11587	431-441	http://purl.obolibrary.org/obo/GO_0065007	denotes	regulation
T11588	1002-1021	http://purl.obolibrary.org/obo/GO_0045289	denotes	luciferase activity
T11589	1235-1254	http://purl.obolibrary.org/obo/GO_0045289	denotes	luciferase activity
T11590	1002-1021	http://purl.obolibrary.org/obo/GO_0047077	denotes	luciferase activity
T11591	1235-1254	http://purl.obolibrary.org/obo/GO_0047077	denotes	luciferase activity
T11592	1002-1021	http://purl.obolibrary.org/obo/GO_0047712	denotes	luciferase activity
T11593	1235-1254	http://purl.obolibrary.org/obo/GO_0047712	denotes	luciferase activity
T11594	1002-1021	http://purl.obolibrary.org/obo/GO_0050248	denotes	luciferase activity
T11595	1235-1254	http://purl.obolibrary.org/obo/GO_0050248	denotes	luciferase activity
T11596	1002-1021	http://purl.obolibrary.org/obo/GO_0050397	denotes	luciferase activity
T11597	1235-1254	http://purl.obolibrary.org/obo/GO_0050397	denotes	luciferase activity
T11598	1268-1274	http://purl.obolibrary.org/obo/GO_0007613	denotes	memory
T26942	3100-3106	http://purl.obolibrary.org/obo/GO_0007613	denotes	memory
T26943	3628-3641	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription

GO-MF

Id	Subject	Object	Predicate	Lexical cue
T12586	174-181	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T12587	222-229	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T12588	1197-1204	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T12589	1776-1783	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T12590	1817-1824	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T12591	2005-2012	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T12592	2408-2415	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T12593	1002-1021	http://purl.obolibrary.org/obo/GO_0045289	denotes	luciferase activity
T12594	1235-1254	http://purl.obolibrary.org/obo/GO_0045289	denotes	luciferase activity
T12595	1002-1021	http://purl.obolibrary.org/obo/GO_0047077	denotes	luciferase activity
T12596	1235-1254	http://purl.obolibrary.org/obo/GO_0047077	denotes	luciferase activity
T12597	1002-1021	http://purl.obolibrary.org/obo/GO_0047712	denotes	luciferase activity
T12598	1235-1254	http://purl.obolibrary.org/obo/GO_0047712	denotes	luciferase activity
T12599	1002-1021	http://purl.obolibrary.org/obo/GO_0050248	denotes	luciferase activity
T12600	1235-1254	http://purl.obolibrary.org/obo/GO_0050248	denotes	luciferase activity
T12601	1002-1021	http://purl.obolibrary.org/obo/GO_0050397	denotes	luciferase activity
T12602	1235-1254	http://purl.obolibrary.org/obo/GO_0050397	denotes	luciferase activity
T12603	2239-2247	http://purl.obolibrary.org/obo/GO_0003823	denotes	antibody
T27574	3541-3548	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T27575	3956-3963	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding

GO-CC

Id	Subject	Object	Predicate	Lexical cue
T12604	568-573	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12605	603-608	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12606	621-626	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12607	635-640	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12608	841-846	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12609	892-897	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12610	985-990	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12611	1289-1294	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12612	1363-1368	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12613	1540-1545	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12614	1887-1892	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12615	1903-1908	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12616	1951-1956	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12617	1986-1991	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12618	2312-2317	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12619	2336-2341	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T12620	2182-2191	http://purl.obolibrary.org/obo/GO_0000785	denotes	chromatin
T12621	2239-2247	http://purl.obolibrary.org/obo/GO_0019815	denotes	antibody
T12622	2239-2247	http://purl.obolibrary.org/obo/GO_0042571	denotes	antibody
T27576	2537-2542	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T27577	2566-2571	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T27578	2890-2895	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T27579	3127-3132	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T27580	3459-3464	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T27581	3531-3536	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T27582	3918-3923	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells

sentences

Id	Subject	Object	Predicate	Lexical cue
T11568	0-34	Sentence	denotes	GATA3 Represses the FOXP3 Promoter
T11569	35-212	Sentence	denotes	To investigate the molecular mechanism of GATA3-mediated repression of human FOXP3, the human FOXP3 promoter was studied and a palindromic binding site for GATA3 was discovered.
T11570	213-307	Sentence	denotes	The GATA-binding site is located 303 bp upstream from the transcription start site (TSS) [24].
T11571	308-442	Sentence	denotes	This site is highly conserved between humans, mice, and rats (Figure S4) and may therefore play an important role in FOXP3 regulation.
T11572	443-531	Sentence	denotes	The functional relevance of this site was studied using a FOXP3-promoter construct [24].
T11573	532-733	Sentence	denotes	We transfected human primary CD4+ T cells, in vitro differentiated Th2 cells, and Jurkat cells (Jurkat cells are known to constitutively express GATA3 [25,26]), and we measured FOXP3 promoter activity.
T11574	734-949	Sentence	denotes	The promoter was not active in the GATA3-expressing cell line Jurkat or in the in vitro-differentiated Th2 cells, whereas the construct was active in the CD4 cells, which express a lower amount of GATA3 (Figure 8A).
T11575	950-1089	Sentence	denotes	Overexpression of GATA3 in naive T cells diminished luciferase activity of the FOXP3 promoter compared with the control vector (Figure 8B).
T11576	1090-1210	Sentence	denotes	To further address the function of the GATA3 site, we inserted a site-specific mutation deleting the GATA3-binding site.
T11577	1211-1444	Sentence	denotes	This mutation increased luciferase activity by 3-fold in memory CD4+CD45RO+ T cells, whereas no difference was observed in naive (GATA3–) CD4+CD45RA+ T cells, revealing a repressor activity of GATA3 on the FOXP3 promoter (Figure 8C).
T11578	1445-1535	Sentence	denotes	Furthermore GATA3 binds directly to the FOXP3 promoter as investigated by pull-down assay.
T11579	1536-1789	Sentence	denotes	HEK cells were transiently transfected with GATA3 or a control vector, and increasing amounts of lysates were incubated with oligonucleotides containing the GATA3 site of the FOXP3 promoter or a control oligonucleotide with a mutated GATA3-binding site.
T11580	1790-1854	Sentence	denotes	After the pull-down, GATA3 binding was detected by Western blot.
T11581	1855-1941	Sentence	denotes	Similarly, GATA3-expressing Th2 cells and iTreg cells were subjected to this approach.
T11582	1942-2041	Sentence	denotes	Only HEK cells overexpressing GATA3 and Th2 cells showed GATA3-binding activity (Figure 8D and 8E).
T11583	2042-2121	Sentence	denotes	These experiments demonstrated that GATA3 binds the palindromic FOXP3 promoter.
T11584	2122-2354	Sentence	denotes	To gain insights into the in vivo situation, we performed a chromatin immunoprecipitation (ChIP) using an anti-GATA3 antibody and showed that GATA3 binds to the FOXP3 promoter region in Th2 cells, but not in iTreg cells (Figure 7F).
T11585	2355-2469	Sentence	denotes	Taken together these data demonstrate that the GATA3-binding to the FOXP3 promoter is repressing FOXP3 expression.
T26927	2480-2520	Sentence	denotes	GATA3 Represses the Human FOXP3 Promoter
T26928	2521-2719	Sentence	denotes	(A) Jurkat, Th2 cells, and human primary CD4 cells were transfected with an empty vector (pGL3 basic) or a vector containing the putative FOXP3 promoter region fused to the luciferase reporter gene.
T26929	2720-2873	Sentence	denotes	Bars show the mean ± SD of arbitrary light units normalized for renilla luciferase of four independent experiments; samples were measured in triplicates.
T26930	2874-3015	Sentence	denotes	(B) Naive CD4 T cells were transfected with the FOXP3 promoter reporter construct together with a GATA3 expression vector or an empty vector.
T26931	3016-3073	Sentence	denotes	Bars show the mean ± SD of three independent experiments.
T26932	3074-3259	Sentence	denotes	(C) Naive (left panel) or memory (right panel) CD4 T cells were transfected with wild-type or a GATA3 mutated 511-FOXP3 promoter reporter construct and activated with PMA and ionomycin.
T26933	3260-3414	Sentence	denotes	Bars show the mean ± SD of arbitrary light units normalized for renilla luciferase of eight independent experiments; samples were measured in triplicates.
T26934	3415-3606	Sentence	denotes	(D) Nuclear extracts were prepared from HEK cells transfected with GATA3 or an empty vector, (E) Th1, Th2, or iTreg cells and binding factors precipitated using biotinylated oligonucleotides.
T26935	3607-3692	Sentence	denotes	The oligonucleotides–transcription factor complexes were separated on a SDS-PAGE gel.
T26936	3693-3794	Sentence	denotes	The amounts of GATA3 protein in the precipitates were assessed by immunoblotting with anti-GATA3 mAb.
T26937	3795-3844	Sentence	denotes	Total nuclear extracts were also run as controls.
T26938	3845-3900	Sentence	denotes	Data are representative of three different experiments.
T26939	3901-3986	Sentence	denotes	(F) iTreg or Th2 cells were analyzed by ChIP for GATA3 binding to the FOXP3 promoter.
T26940	3987-4094	Sentence	denotes	The “input” represents PCR amplification of the total sample, which was not subjected to any precipitation.
T26941	4095-4155	Sentence	denotes	Results are representative of three independent experiments.
T176	0-34	Sentence	denotes	GATA3 Represses the FOXP3 Promoter
T177	35-212	Sentence	denotes	To investigate the molecular mechanism of GATA3-mediated repression of human FOXP3, the human FOXP3 promoter was studied and a palindromic binding site for GATA3 was discovered.
T178	213-307	Sentence	denotes	The GATA-binding site is located 303 bp upstream from the transcription start site (TSS) [24].
T179	308-442	Sentence	denotes	This site is highly conserved between humans, mice, and rats (Figure S4) and may therefore play an important role in FOXP3 regulation.
T180	443-531	Sentence	denotes	The functional relevance of this site was studied using a FOXP3-promoter construct [24].
T181	532-733	Sentence	denotes	We transfected human primary CD4+ T cells, in vitro differentiated Th2 cells, and Jurkat cells (Jurkat cells are known to constitutively express GATA3 [25,26]), and we measured FOXP3 promoter activity.
T182	734-949	Sentence	denotes	The promoter was not active in the GATA3-expressing cell line Jurkat or in the in vitro-differentiated Th2 cells, whereas the construct was active in the CD4 cells, which express a lower amount of GATA3 (Figure 8A).
T183	950-1089	Sentence	denotes	Overexpression of GATA3 in naive T cells diminished luciferase activity of the FOXP3 promoter compared with the control vector (Figure 8B).
T184	1090-1210	Sentence	denotes	To further address the function of the GATA3 site, we inserted a site-specific mutation deleting the GATA3-binding site.
T185	1211-1444	Sentence	denotes	This mutation increased luciferase activity by 3-fold in memory CD4+CD45RO+ T cells, whereas no difference was observed in naive (GATA3–) CD4+CD45RA+ T cells, revealing a repressor activity of GATA3 on the FOXP3 promoter (Figure 8C).
T186	1445-1535	Sentence	denotes	Furthermore GATA3 binds directly to the FOXP3 promoter as investigated by pull-down assay.
T187	1536-1789	Sentence	denotes	HEK cells were transiently transfected with GATA3 or a control vector, and increasing amounts of lysates were incubated with oligonucleotides containing the GATA3 site of the FOXP3 promoter or a control oligonucleotide with a mutated GATA3-binding site.
T188	1790-1854	Sentence	denotes	After the pull-down, GATA3 binding was detected by Western blot.
T189	1855-1941	Sentence	denotes	Similarly, GATA3-expressing Th2 cells and iTreg cells were subjected to this approach.
T190	1942-2041	Sentence	denotes	Only HEK cells overexpressing GATA3 and Th2 cells showed GATA3-binding activity (Figure 8D and 8E).
T191	2042-2121	Sentence	denotes	These experiments demonstrated that GATA3 binds the palindromic FOXP3 promoter.
T192	2122-2354	Sentence	denotes	To gain insights into the in vivo situation, we performed a chromatin immunoprecipitation (ChIP) using an anti-GATA3 antibody and showed that GATA3 binds to the FOXP3 promoter region in Th2 cells, but not in iTreg cells (Figure 7F).
T193	2355-2469	Sentence	denotes	Taken together these data demonstrate that the GATA3-binding to the FOXP3 promoter is repressing FOXP3 expression.
T194	2470-2520	Sentence	denotes	Figure 8 GATA3 Represses the Human FOXP3 Promoter
T195	2521-2719	Sentence	denotes	(A) Jurkat, Th2 cells, and human primary CD4 cells were transfected with an empty vector (pGL3 basic) or a vector containing the putative FOXP3 promoter region fused to the luciferase reporter gene.
T196	2720-2873	Sentence	denotes	Bars show the mean ± SD of arbitrary light units normalized for renilla luciferase of four independent experiments; samples were measured in triplicates.
T197	2874-3015	Sentence	denotes	(B) Naive CD4 T cells were transfected with the FOXP3 promoter reporter construct together with a GATA3 expression vector or an empty vector.
T198	3016-3073	Sentence	denotes	Bars show the mean ± SD of three independent experiments.
T199	3074-3259	Sentence	denotes	(C) Naive (left panel) or memory (right panel) CD4 T cells were transfected with wild-type or a GATA3 mutated 511-FOXP3 promoter reporter construct and activated with PMA and ionomycin.
T200	3260-3414	Sentence	denotes	Bars show the mean ± SD of arbitrary light units normalized for renilla luciferase of eight independent experiments; samples were measured in triplicates.
T201	3415-3606	Sentence	denotes	(D) Nuclear extracts were prepared from HEK cells transfected with GATA3 or an empty vector, (E) Th1, Th2, or iTreg cells and binding factors precipitated using biotinylated oligonucleotides.
T202	3607-3692	Sentence	denotes	The oligonucleotides–transcription factor complexes were separated on a SDS-PAGE gel.
T203	3693-3794	Sentence	denotes	The amounts of GATA3 protein in the precipitates were assessed by immunoblotting with anti-GATA3 mAb.
T204	3795-3844	Sentence	denotes	Total nuclear extracts were also run as controls.
T205	3845-3900	Sentence	denotes	Data are representative of three different experiments.
T206	3901-3986	Sentence	denotes	(F) iTreg or Th2 cells were analyzed by ChIP for GATA3 binding to the FOXP3 promoter.
T207	3987-4094	Sentence	denotes	The “input” represents PCR amplification of the total sample, which was not subjected to any precipitation.
T208	4095-4155	Sentence	denotes	Results are representative of three independent experiments.

events-check-again

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T12887	0-5	Protein	denotes	GATA3
T12888	6-15	Negative_regulation	denotes	Represses
T12889	20-25	Protein	denotes	FOXP3
T12890	26-34	Entity	denotes	Promoter
T12891	77-82	Protein	denotes	GATA3
T12892	92-102	Negative_regulation	denotes	repression		true
T12893	112-117	Protein	denotes	FOXP3
T12894	129-134	Protein	denotes	FOXP3
T12895	191-196	Protein	denotes	GATA3
T12896	217-234	Entity	denotes	GATA-binding site
T12897	399-421	Regulation	denotes	play an important role		true
T12898	425-430	Protein	denotes	FOXP3
T12899	431-441	Regulation	denotes	regulation
T12900	501-506	Protein	denotes	FOXP3
T12901	561-564	Protein	denotes	CD4
T12902	669-676	Gene_expression	denotes	express
T12903	677-682	Protein	denotes	GATA3
T12904	709-714	Protein	denotes	FOXP3
T12905	715-723	Entity	denotes	promoter
T12906	769-774	Protein	denotes	GATA3
T12907	775-785	Gene_expression	denotes	expressing
T12908	874-880	Positive_regulation	denotes	active
T12909	888-891	Protein	denotes	CD4
T12910	905-912	Gene_expression	denotes	express	true
T12911	931-936	Protein	denotes	GATA3
T12912	950-964	Positive_regulation	denotes	Overexpression
T12913	968-973	Protein	denotes	GATA3
T12914	1029-1034	Protein	denotes	FOXP3
T12915	1178-1186	Negative_regulation	denotes	deleting
T12916	1191-1209	Entity	denotes	GATA3-binding site
T12917	1275-1278	Protein	denotes	CD4
T12918	1279-1285	Protein	denotes	CD45RO
T12919	1341-1346	Protein	denotes	GATA3
T12920	1349-1352	Protein	denotes	CD4
T12921	1353-1359	Protein	denotes	CD45RA
T12922	1382-1391	Negative_regulation	denotes	repressor
T12923	1404-1409	Protein	denotes	GATA3
T12924	1417-1422	Protein	denotes	FOXP3
T12925	1423-1431	Entity	denotes	promoter
T12926	1457-1462	Protein	denotes	GATA3
T12927	1463-1468	Binding	denotes	binds
T12928	1485-1490	Protein	denotes	FOXP3
T12929	1491-1499	Entity	denotes	promoter
T12930	1580-1585	Protein	denotes	GATA3
T12931	1711-1716	Protein	denotes	FOXP3
T12932	1811-1816	Protein	denotes	GATA3
T12933	1817-1824	Binding	denotes	binding		true
T12934	1866-1871	Protein	denotes	GATA3
T12935	1872-1882	Gene_expression	denotes	expressing
T12936	1957-1971	Gene_expression	denotes	overexpressing
T12937	1972-1977	Protein	denotes	GATA3
T12938	1999-2004	Protein	denotes	GATA3
T12939	2005-2012	Binding	denotes	binding
T12940	2078-2083	Protein	denotes	GATA3
T12941	2084-2089	Binding	denotes	binds
T12942	2106-2111	Protein	denotes	FOXP3
T12943	2112-2120	Entity	denotes	promoter
T12944	2233-2238	Protein	denotes	GATA3
T12945	2264-2269	Protein	denotes	GATA3
T12946	2270-2275	Binding	denotes	binds
T12947	2283-2288	Protein	denotes	FOXP3
T12948	2289-2304	Entity	denotes	promoter region
T12949	2402-2407	Protein	denotes	GATA3
T12950	2408-2415	Binding	denotes	binding
T12951	2423-2428	Protein	denotes	FOXP3
T12952	2441-2451	Negative_regulation	denotes	repressing
T12953	2452-2457	Protein	denotes	FOXP3
T12954	2458-2468	Gene_expression	denotes	expression
T27678	2480-2485	Protein	denotes	GATA3
T27679	2486-2495	Negative_regulation	denotes	Represses
T27680	2506-2511	Protein	denotes	FOXP3
T27681	2512-2520	Entity	denotes	Promoter
T27682	2562-2565	Protein	denotes	CD4
T27683	2659-2664	Protein	denotes	FOXP3
T27684	2694-2704	Protein	denotes	luciferase
T27685	2792-2802	Protein	denotes	luciferase
T27686	2884-2887	Protein	denotes	CD4
T27687	2922-2927	Protein	denotes	FOXP3
T27688	2972-2977	Protein	denotes	GATA3
T27689	2978-2988	Gene_expression	denotes	expression
T27690	3121-3124	Protein	denotes	CD4
T27691	3170-3175	Protein	denotes	GATA3
T27692	3188-3193	Protein	denotes	FOXP3
T27693	3332-3342	Protein	denotes	luciferase
T27694	3482-3487	Protein	denotes	GATA3
T27695	3697-3704	Gene_expression	denotes	amounts		true
T27696	3708-3713	Protein	denotes	GATA3
T27697	3784-3789	Protein	denotes	GATA3
T27698	3950-3955	Protein	denotes	GATA3
T27699	3956-3963	Binding	denotes	binding		true
T27700	3971-3976	Protein	denotes	FOXP3
T27701	3977-3985	Entity	denotes	promoter
R9656	T12887	T12888	causeOf	GATA3,Represses
R9657	T12890	T12888	themeOf	Promoter,Represses
R9658	T12890	T12889	partOf	Promoter,FOXP3
R9659	T12891	T12892	causeOf	GATA3,repression
R9660	T12893	T12892	themeOf	FOXP3,repression
R9661	T12896	T12897	causeOf	GATA-binding site,play an important role
R9662	T12896	T12894	partOf	GATA-binding site,FOXP3
R9663	T12898	T12899	themeOf	FOXP3,regulation
R9664	T12899	T12897	themeOf	regulation,play an important role
R9665	T12903	T12902	themeOf	GATA3,express
R9666	T12905	T12908	themeOf	promoter,active
R9667	T12905	T12904	partOf	promoter,FOXP3
R9668	T12906	T12907	themeOf	GATA3,expressing
R9669	T12910	T12908	causeOf	express,active
R9670	T12911	T12910	themeOf	GATA3,express
R9671	T12913	T12912	themeOf	GATA3,Overexpression
R9672	T12916	T12915	themeOf	GATA3-binding site,deleting
R9673	T12916	T12914	partOf	GATA3-binding site,FOXP3
R9674	T12923	T12922	causeOf	GATA3,repressor
R9675	T12925	T12922	themeOf	promoter,repressor
R9676	T12925	T12924	partOf	promoter,FOXP3
R9677	T12926	T12927	themeOf	GATA3,binds
R9678	T12929	T12927	themeOf	promoter,binds
R9679	T12929	T12928	partOf	promoter,FOXP3
R9680	T12932	T12933	themeOf	GATA3,binding
R9681	T12934	T12935	themeOf	GATA3,expressing
R9682	T12937	T12936	themeOf	GATA3,overexpressing
R9683	T12938	T12939	themeOf	GATA3,binding
R9684	T12940	T12941	themeOf	GATA3,binds
R9685	T12943	T12941	themeOf	promoter,binds
R9686	T12943	T12942	partOf	promoter,FOXP3
R9687	T12945	T12946	themeOf	GATA3,binds
R9688	T12948	T12946	themeOf	promoter region,binds
R9689	T12948	T12947	partOf	promoter region,FOXP3
R9690	T12949	T12950	themeOf	GATA3,binding
R9691	T12950	T12952	causeOf	binding,repressing
R9692	T12951	T12950	themeOf	FOXP3,binding
R9693	T12953	T12954	themeOf	FOXP3,expression
R9694	T12954	T12952	themeOf	expression,repressing
R20432	T27678	T27679	causeOf	GATA3,Represses
R20433	T27681	T27679	themeOf	Promoter,Represses
R20434	T27681	T27680	partOf	Promoter,FOXP3
R20435	T27688	T27689	themeOf	GATA3,expression
R20436	T27696	T27695	themeOf	GATA3,amounts
R20437	T27698	T27699	themeOf	GATA3,binding
R20438	T27701	T27699	themeOf	promoter,binding
R20439	T27701	T27700	partOf	promoter,FOXP3

bionlp-st-ge-2016-reference-tees

Id	Subject	Object	Predicate	Lexical cue
T12645	950-964	Positive_regulation	denotes	Overexpression
T12646	1013-1021	Positive_regulation	denotes	activity
T12647	1013-1021	Positive_regulation	denotes	activity
T12648	991-1001	Negative_regulation	denotes	diminished
T12649	991-1001	Negative_regulation	denotes	diminished
T12650	1129-1139	Protein	denotes	GATA3 site
T12651	1191-1209	Protein	denotes	GATA3-binding site
T12652	1235-1245	Protein	denotes	luciferase
T12653	1275-1278	Protein	denotes	CD4
T12654	1279-1285	Protein	denotes	CD45RO
T12655	1349-1352	Protein	denotes	CD4
T12656	1353-1359	Protein	denotes	CD45RA
T12657	1404-1409	Protein	denotes	GATA3
T12658	1417-1431	Protein	denotes	FOXP3 promoter
T12659	1225-1234	Positive_regulation	denotes	increased
T12660	1457-1462	Protein	denotes	GATA3
T12661	1485-1499	Protein	denotes	FOXP3 promoter
T12662	1463-1468	Binding	denotes	binds
T12663	1463-1468	Binding	denotes	binds
T12664	1580-1585	Protein	denotes	GATA3
T12665	1693-1703	Protein	denotes	GATA3 site
T12666	1711-1725	Protein	denotes	FOXP3 promoter
T12667	1770-1788	Protein	denotes	GATA3-binding site
T12668	1678-1688	Negative_regulation	denotes	containing
T12669	1811-1816	Protein	denotes	GATA3
T12670	1817-1824	Binding	denotes	binding
T12671	1866-1871	Protein	denotes	GATA3
T12672	1872-1882	Gene_expression	denotes	expressing
T12673	1972-1977	Protein	denotes	GATA3
T12674	1999-2004	Protein	denotes	GATA3
T12675	1957-1971	Gene_expression	denotes	overexpressing
T12676	2005-2012	Binding	denotes	binding
T12677	2078-2083	Protein	denotes	GATA3
T12678	2106-2120	Protein	denotes	FOXP3 promoter
T12679	2084-2089	Binding	denotes	binds
T12680	2084-2089	Binding	denotes	binds
T12681	2228-2247	Protein	denotes	anti-GATA3 antibody
T12682	2264-2269	Protein	denotes	GATA3
T12683	2283-2297	Protein	denotes	FOXP3 promoter
T12684	2298-2304	Entity	denotes	region
T12685	2270-2275	Binding	denotes	binds
T12686	2402-2407	Protein	denotes	GATA3
T12687	2423-2437	Protein	denotes	FOXP3 promoter
T12688	2452-2457	Protein	denotes	FOXP3
T12689	2408-2415	Binding	denotes	binding
T12690	2458-2468	Gene_expression	denotes	expression
T12691	2441-2451	Negative_regulation	denotes	repressing
T27583	2480-2485	Protein	denotes	GATA3
T27584	2500-2520	Protein	denotes	Human FOXP3 Promoter
T27585	2486-2495	Negative_regulation	denotes	Represses
T27586	2562-2565	Protein	denotes	CD4
T27587	2659-2673	Protein	denotes	FOXP3 promoter
T27588	2694-2718	Protein	denotes	luciferase reporter gene
T27589	2784-2802	Protein	denotes	renilla luciferase
T27590	2884-2889	Protein	denotes	CD4 T
T27591	2922-2936	Protein	denotes	FOXP3 promoter
T27592	2972-2977	Protein	denotes	GATA3
T27593	2978-2988	Gene_expression	denotes	expression
T27594	3121-3126	Protein	denotes	CD4 T
T27595	3170-3221	Protein	denotes	GATA3 mutated 511-FOXP3 promoter reporter construct
T27596	3324-3342	Protein	denotes	renilla luciferase
T27597	3482-3487	Protein	denotes	GATA3
T27598	3708-3721	Protein	denotes	GATA3 protein
T27599	3779-3793	Protein	denotes	anti-GATA3 mAb
T27600	3697-3704	Gene_expression	denotes	amounts
T27601	3941-3945	Protein	denotes	ChIP
T27602	3950-3955	Protein	denotes	GATA3
T27603	3971-3985	Protein	denotes	FOXP3 promoter
T27604	3956-3963	Binding	denotes	binding
T27605	3956-3963	Binding	denotes	binding
T12623	0-5	Protein	denotes	GATA3
T12624	20-34	Protein	denotes	FOXP3 Promoter
T12625	6-15	Negative_regulation	denotes	Represses
T12626	77-82	Protein	denotes	GATA3
T12627	106-117	Protein	denotes	human FOXP3
T12628	123-143	Protein	denotes	human FOXP3 promoter
T12629	191-196	Protein	denotes	GATA3
T12630	92-102	Negative_regulation	denotes	repression
T12631	425-430	Protein	denotes	FOXP3
T12632	431-441	Regulation	denotes	regulation
T12633	417-421	Regulation	denotes	role
T12634	501-506	Protein	denotes	FOXP3
T12635	561-565	Protein	denotes	CD4+
T12636	709-723	Protein	denotes	FOXP3 promoter
T12637	769-774	Protein	denotes	GATA3
T12638	888-891	Protein	denotes	CD4
T12639	931-936	Protein	denotes	GATA3
T12640	775-785	Gene_expression	denotes	expressing
T12641	905-912	Gene_expression	denotes	express
T12642	968-973	Protein	denotes	GATA3
T12643	1002-1012	Protein	denotes	luciferase
T12644	1029-1043	Protein	denotes	FOXP3 promoter
R9543	T12677	T12679	themeOf	GATA3,binds
R9544	T12677	T12680	themeOf	GATA3,binds
R9545	T12678	T12680	themeOf	FOXP3 promoter,binds
R9546	T12682	T12685	themeOf	GATA3,binds
R9547	T12683	T12685	themeOf	FOXP3 promoter,binds
R9548	T12683	T12684	partOf	FOXP3 promoter,region
R9549	T12684	T12685	Site	region,binds
R9550	T12686	T12689	themeOf	GATA3,binding
R9551	T12687	T12689	themeOf	FOXP3 promoter,binding
R9552	T12688	T12690	themeOf	FOXP3,expression
R9553	T12689	T12691	causeOf	binding,repressing
R9554	T12690	T12691	themeOf	expression,repressing
R20402	T27583	T27585	causeOf	GATA3,Represses
R20403	T27584	T27585	themeOf	Human FOXP3 Promoter,Represses
R20404	T27592	T27593	themeOf	GATA3,expression
R20405	T27598	T27600	themeOf	GATA3 protein,amounts
R20406	T27602	T27604	themeOf	GATA3,binding
R20407	T27602	T27605	themeOf	GATA3,binding
R20408	T27603	T27605	themeOf	FOXP3 promoter,binding
R9519	T12623	T12625	causeOf	GATA3,Represses
R9520	T12624	T12625	themeOf	FOXP3 Promoter,Represses
R9521	T12626	T12630	causeOf	GATA3,repression
R9522	T12627	T12630	themeOf	human FOXP3,repression
R9523	T12631	T12632	themeOf	FOXP3,regulation
R9524	T12632	T12633	themeOf	regulation,role
R9525	T12637	T12640	themeOf	GATA3,expressing
R9526	T12639	T12641	themeOf	GATA3,express
R9527	T12642	T12645	themeOf	GATA3,Overexpression
R9528	T12643	T12646	themeOf	luciferase,activity
R9529	T12644	T12647	themeOf	FOXP3 promoter,activity
R9530	T12645	T12648	causeOf	Overexpression,diminished
R9531	T12645	T12649	causeOf	Overexpression,diminished
R9532	T12646	T12648	themeOf	activity,diminished
R9533	T12647	T12649	themeOf	activity,diminished
R9534	T12652	T12659	themeOf	luciferase,increased
R9535	T12660	T12662	themeOf	GATA3,binds
R9536	T12660	T12663	themeOf	GATA3,binds
R9537	T12661	T12663	themeOf	FOXP3 promoter,binds
R9538	T12665	T12668	themeOf	GATA3 site,containing
R9539	T12669	T12670	themeOf	GATA3,binding
R9540	T12671	T12672	themeOf	GATA3,expressing
R9541	T12673	T12675	themeOf	GATA3,overexpressing
R9542	T12674	T12676	themeOf	GATA3,binding

bionlp-st-ge-2016-reference

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T11552	2005-2012	Binding	denotes	binding
T11553	2078-2083	Protein	denotes	GATA3
T11554	2084-2089	Binding	denotes	binds
T11555	2106-2111	Protein	denotes	FOXP3
T11556	2112-2120	Entity	denotes	promoter
T11557	2233-2238	Protein	denotes	GATA3
T11558	2264-2269	Protein	denotes	GATA3
T11559	2270-2275	Binding	denotes	binds
T11560	2283-2288	Protein	denotes	FOXP3
T11561	2289-2304	Entity	denotes	promoter region
T11562	2402-2407	Protein	denotes	GATA3
T11563	2408-2415	Binding	denotes	binding
T11564	2423-2428	Protein	denotes	FOXP3
T11565	2441-2451	Negative_regulation	denotes	repressing
T11566	2452-2457	Protein	denotes	FOXP3
T11567	2458-2468	Gene_expression	denotes	expression
T11550	1972-1977	Protein	denotes	GATA3
T11500	0-5	Protein	denotes	GATA3
T11501	6-15	Negative_regulation	denotes	Represses
T11502	20-25	Protein	denotes	FOXP3
T11503	26-34	Entity	denotes	Promoter
T11504	77-82	Protein	denotes	GATA3
T11505	92-102	Negative_regulation	denotes	repression		true
T11506	112-117	Protein	denotes	FOXP3
T11507	129-134	Protein	denotes	FOXP3
T11508	191-196	Protein	denotes	GATA3
T11509	217-234	Entity	denotes	GATA-binding site
T11510	399-421	Regulation	denotes	play an important role		true
T11511	425-430	Protein	denotes	FOXP3
T11512	431-441	Regulation	denotes	regulation
T11513	501-506	Protein	denotes	FOXP3
T11514	561-564	Protein	denotes	CD4
T11515	669-676	Gene_expression	denotes	express
T11516	677-682	Protein	denotes	GATA3
T11517	709-714	Protein	denotes	FOXP3
T11518	715-723	Entity	denotes	promoter
T11519	769-774	Protein	denotes	GATA3
T11520	775-785	Gene_expression	denotes	expressing
T11521	874-880	Positive_regulation	denotes	active
T11522	888-891	Protein	denotes	CD4
T11523	905-912	Gene_expression	denotes	express	true
T11524	931-936	Protein	denotes	GATA3
T11525	950-964	Positive_regulation	denotes	Overexpression
T11526	968-973	Protein	denotes	GATA3
T11527	1029-1034	Protein	denotes	FOXP3
T11528	1178-1186	Negative_regulation	denotes	deleting
T11529	1191-1209	Entity	denotes	GATA3-binding site
T11530	1275-1278	Protein	denotes	CD4
T11531	1279-1285	Protein	denotes	CD45RO
T11532	1341-1346	Protein	denotes	GATA3
T11533	1349-1352	Protein	denotes	CD4
T11534	1353-1359	Protein	denotes	CD45RA
T11535	1382-1391	Negative_regulation	denotes	repressor
T11536	1404-1409	Protein	denotes	GATA3
T11537	1417-1422	Protein	denotes	FOXP3
T11538	1423-1431	Entity	denotes	promoter
T11539	1457-1462	Protein	denotes	GATA3
T11540	1463-1468	Binding	denotes	binds
T11541	1485-1490	Protein	denotes	FOXP3
T11542	1491-1499	Entity	denotes	promoter
T11543	1580-1585	Protein	denotes	GATA3
T11544	1711-1716	Protein	denotes	FOXP3
T11545	1811-1816	Protein	denotes	GATA3
T11546	1817-1824	Binding	denotes	binding		true
T11547	1866-1871	Protein	denotes	GATA3
T11548	1872-1882	Gene_expression	denotes	expressing
T11549	1957-1971	Gene_expression	denotes	overexpressing
T11551	1999-2004	Protein	denotes	GATA3
T26903	2480-2485	Protein	denotes	GATA3
T26904	2486-2495	Negative_regulation	denotes	Represses
T26905	2506-2511	Protein	denotes	FOXP3
T26906	2512-2520	Entity	denotes	Promoter
T26907	2562-2565	Protein	denotes	CD4
T26908	2659-2664	Protein	denotes	FOXP3
T26909	2694-2704	Protein	denotes	luciferase
T26910	2792-2802	Protein	denotes	luciferase
T26911	2884-2887	Protein	denotes	CD4
T26912	2922-2927	Protein	denotes	FOXP3
T26913	2972-2977	Protein	denotes	GATA3
T26914	2978-2988	Gene_expression	denotes	expression
T26915	3121-3124	Protein	denotes	CD4
T26916	3170-3175	Protein	denotes	GATA3
T26917	3188-3193	Protein	denotes	FOXP3
T26918	3332-3342	Protein	denotes	luciferase
T26919	3482-3487	Protein	denotes	GATA3
T26920	3697-3704	Gene_expression	denotes	amounts		true
T26921	3708-3713	Protein	denotes	GATA3
T26922	3784-3789	Protein	denotes	GATA3
T26923	3950-3955	Protein	denotes	GATA3
T26924	3956-3963	Binding	denotes	binding		true
T26925	3971-3976	Protein	denotes	FOXP3
T26926	3977-3985	Entity	denotes	promoter
R8606	T11547	T11548	themeOf	GATA3,expressing
R8607	T11550	T11549	themeOf	GATA3,overexpressing
R8608	T11551	T11552	themeOf	GATA3,binding
R8609	T11553	T11554	themeOf	GATA3,binds
R8610	T11556	T11554	themeOf	promoter,binds
R8611	T11556	T11555	partOf	promoter,FOXP3
R8612	T11558	T11559	themeOf	GATA3,binds
R8613	T11561	T11559	themeOf	promoter region,binds
R8614	T11561	T11560	partOf	promoter region,FOXP3
R8615	T11562	T11563	themeOf	GATA3,binding
R8616	T11563	T11565	causeOf	binding,repressing
R8617	T11564	T11563	themeOf	FOXP3,binding
R8618	T11566	T11567	themeOf	FOXP3,expression
R8619	T11567	T11565	themeOf	expression,repressing
R19810	T26903	T26904	causeOf	GATA3,Represses
R19811	T26906	T26904	themeOf	Promoter,Represses
R19812	T26906	T26905	partOf	Promoter,FOXP3
R19813	T26913	T26914	themeOf	GATA3,expression
R19814	T26921	T26920	themeOf	GATA3,amounts
R19815	T26923	T26924	themeOf	GATA3,binding
R19816	T26926	T26924	themeOf	promoter,binding
R19817	T26926	T26925	partOf	promoter,FOXP3
R8581	T11500	T11501	causeOf	GATA3,Represses
R8582	T11503	T11501	themeOf	Promoter,Represses
R8583	T11503	T11502	partOf	Promoter,FOXP3
R8584	T11504	T11505	causeOf	GATA3,repression
R8585	T11506	T11505	themeOf	FOXP3,repression
R8586	T11509	T11510	causeOf	GATA-binding site,play an important role
R8587	T11509	T11507	partOf	GATA-binding site,FOXP3
R8588	T11511	T11512	themeOf	FOXP3,regulation
R8589	T11512	T11510	themeOf	regulation,play an important role
R8590	T11516	T11515	themeOf	GATA3,express
R8591	T11518	T11521	themeOf	promoter,active
R8592	T11518	T11517	partOf	promoter,FOXP3
R8593	T11519	T11520	themeOf	GATA3,expressing
R8594	T11523	T11521	causeOf	express,active
R8595	T11524	T11523	themeOf	GATA3,express
R8596	T11526	T11525	themeOf	GATA3,Overexpression
R8597	T11529	T11528	themeOf	GATA3-binding site,deleting
R8598	T11529	T11527	partOf	GATA3-binding site,FOXP3
R8599	T11536	T11535	causeOf	GATA3,repressor
R8600	T11538	T11535	themeOf	promoter,repressor
R8601	T11538	T11537	partOf	promoter,FOXP3
R8602	T11539	T11540	themeOf	GATA3,binds
R8603	T11542	T11540	themeOf	promoter,binds
R8604	T11542	T11541	partOf	promoter,FOXP3
R8605	T11545	T11546	themeOf	GATA3,binding

bionlp-st-ge-2016-uniprot

Id	Subject	Object	Predicate	Lexical cue
T12017	0-5	P23771	denotes	GATA3
T12018	20-25	Q9BZS1	denotes	FOXP3
T12019	77-82	P23771	denotes	GATA3
T12020	112-117	Q9BZS1	denotes	FOXP3
T12021	129-134	Q9BZS1	denotes	FOXP3
T12022	191-196	P23771	denotes	GATA3
T12023	425-430	Q9BZS1	denotes	FOXP3
T12024	501-506	Q9BZS1	denotes	FOXP3
T12025	561-564	P01730	denotes	CD4
T12026	677-682	P23771	denotes	GATA3
T12027	709-714	Q9BZS1	denotes	FOXP3
T12028	769-774	P23771	denotes	GATA3
T12029	888-891	P01730	denotes	CD4
T12030	931-936	P23771	denotes	GATA3
T12031	968-973	P23771	denotes	GATA3
T12032	1002-1012	P08659	denotes	luciferase
T12033	1029-1034	Q9BZS1	denotes	FOXP3
T12034	1129-1134	P23771	denotes	GATA3
T12035	1191-1196	P23771	denotes	GATA3
T12036	1235-1245	P08659	denotes	luciferase
T12037	1275-1278	P01730	denotes	CD4
T12038	1279-1285	P08575	denotes	CD45RO
T12039	1341-1346	P23771	denotes	GATA3
T12040	1349-1352	P01730	denotes	CD4
T12041	1353-1359	P08575	denotes	CD45RA
T12042	1404-1409	P23771	denotes	GATA3
T12043	1417-1422	Q9BZS1	denotes	FOXP3
T12044	1457-1462	P23771	denotes	GATA3
T12045	1485-1490	Q9BZS1	denotes	FOXP3
T12046	1580-1585	P23771	denotes	GATA3
T12047	1693-1698	P23771	denotes	GATA3
T12048	1711-1716	Q9BZS1	denotes	FOXP3
T12049	1770-1775	P23771	denotes	GATA3
T12050	1811-1816	P23771	denotes	GATA3
T12051	1866-1871	P23771	denotes	GATA3
T12052	1972-1977	P23771	denotes	GATA3
T12053	1999-2004	P23771	denotes	GATA3
T12054	2078-2083	P23771	denotes	GATA3
T12055	2106-2111	Q9BZS1	denotes	FOXP3
T12056	2233-2238	P23771	denotes	GATA3
T12057	2264-2269	P23771	denotes	GATA3
T12058	2283-2288	Q9BZS1	denotes	FOXP3
T12059	2402-2407	P23771	denotes	GATA3
T12060	2423-2428	Q9BZS1	denotes	FOXP3
T12061	2452-2457	Q9BZS1	denotes	FOXP3
T27223	2480-2485	P23771	denotes	GATA3
T27224	2506-2511	Q9BZS1	denotes	FOXP3
T27225	2562-2565	P01730	denotes	CD4
T27226	2659-2664	Q9BZS1	denotes	FOXP3
T27227	2694-2704	P08659	denotes	luciferase
T27228	2792-2802	P08659	denotes	luciferase
T27229	2884-2887	P01730	denotes	CD4
T27230	2922-2927	Q9BZS1	denotes	FOXP3
T27231	2972-2977	P23771	denotes	GATA3
T27232	3121-3124	P01730	denotes	CD4
T27233	3170-3175	P23771	denotes	GATA3
T27234	3188-3193	Q9BZS1	denotes	FOXP3
T27235	3332-3342	P08659	denotes	luciferase
T27236	3482-3487	P23771	denotes	GATA3
T27237	3708-3713	P23771	denotes	GATA3
T27238	3784-3789	P23771	denotes	GATA3
T27239	3950-3955	P23771	denotes	GATA3
T27240	3971-3976	Q9BZS1	denotes	FOXP3

test2

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T11427	0-5	Protein	denotes	GATA3
T11428	6-15	Negative_regulation	denotes	Represses		true
T11429	20-25	Protein	denotes	FOXP3		true
T11430	26-34	Entity	denotes	Promoter
T11431	77-82	Protein	denotes	GATA3
T11432	83-91	Positive_regulation	denotes	mediated
T11433	92-102	Negative_regulation	denotes	repression
T11434	112-117	Protein	denotes	FOXP3	true
T11435	129-134	Protein	denotes	FOXP3
T11436	135-143	Entity	denotes	promoter
T11437	191-196	Protein	denotes	GATA3
T11438	221-229	Entity	denotes	-binding
T11439	417-421	Regulation	denotes	role		true
T11440	425-430	Protein	denotes	FOXP3
T11441	431-441	Regulation	denotes	regulation
T11442	501-506	Protein	denotes	FOXP3
T11443	561-564	Protein	denotes	CD4
T11444	669-676	Gene_expression	denotes	express
T11445	677-682	Protein	denotes	GATA3
T11446	709-714	Protein	denotes	FOXP3
T11447	715-723	Entity	denotes	promoter
T11448	769-774	Protein	denotes	GATA3
T11449	775-785	Gene_expression	denotes	expressing
T11450	888-891	Protein	denotes	CD4
T11451	905-912	Gene_expression	denotes	express
T11452	931-936	Protein	denotes	GATA3
T11453	950-964	Positive_regulation	denotes	Overexpression
T11454	968-973	Protein	denotes	GATA3
T11455	991-1001	Negative_regulation	denotes	diminished
T11456	1029-1034	Protein	denotes	FOXP3
T11457	1035-1043	Entity	denotes	promoter
T11458	1178-1186	Negative_regulation	denotes	deleting
T11459	1196-1209	Entity	denotes	-binding site
T11460	1225-1234	Positive_regulation	denotes	increased
T11461	1275-1278	Protein	denotes	CD4
T11462	1279-1285	Protein	denotes	CD45RO
T11463	1341-1346	Protein	denotes	GATA3
T11464	1349-1352	Protein	denotes	CD4
T11465	1353-1359	Protein	denotes	CD45RA
T11466	1404-1409	Protein	denotes	GATA3
T11467	1417-1422	Protein	denotes	FOXP3
T11468	1423-1431	Entity	denotes	promoter
T11469	1457-1462	Protein	denotes	GATA3
T11470	1463-1468	Binding	denotes	binds
T11471	1485-1490	Protein	denotes	FOXP3
T11472	1491-1499	Entity	denotes	promoter
T11473	1580-1585	Protein	denotes	GATA3
T11474	1711-1716	Protein	denotes	FOXP3
T11475	1811-1816	Protein	denotes	GATA3
T11476	1817-1824	Binding	denotes	binding
T11477	1866-1871	Protein	denotes	GATA3
T11478	1872-1882	Gene_expression	denotes	expressing
T11479	1957-1971	Gene_expression	denotes	overexpressing
T11480	1972-1977	Protein	denotes	GATA3
T11481	1999-2004	Protein	denotes	GATA3
T11482	2005-2012	Binding	denotes	binding
T11483	2078-2083	Protein	denotes	GATA3
T11484	2084-2089	Binding	denotes	binds
T11485	2106-2111	Protein	denotes	FOXP3
T11486	2112-2120	Entity	denotes	promoter
T11487	2233-2238	Protein	denotes	GATA3
T11488	2264-2269	Protein	denotes	GATA3
T11489	2270-2275	Binding	denotes	binds
T11490	2283-2288	Protein	denotes	FOXP3
T11491	2289-2297	Entity	denotes	promoter
T11492	2298-2304	Entity	denotes	region
T11493	2402-2407	Protein	denotes	GATA3
T11494	2408-2415	Binding	denotes	binding
T11495	2423-2428	Protein	denotes	FOXP3
T11496	2429-2437	Entity	denotes	promoter
T11497	2441-2451	Negative_regulation	denotes	repressing
T11498	2452-2457	Protein	denotes	FOXP3
T11499	2458-2468	Gene_expression	denotes	expression
T26880	2480-2485	Protein	denotes	GATA3
T26881	2486-2495	Negative_regulation	denotes	Represses
T26882	2506-2511	Protein	denotes	FOXP3		true
T26883	2512-2520	Entity	denotes	Promoter		true
T26884	2562-2565	Protein	denotes	CD4
T26885	2659-2664	Protein	denotes	FOXP3
T26886	2694-2704	Protein	denotes	luciferase
T26887	2792-2802	Protein	denotes	luciferase
T26888	2884-2887	Protein	denotes	CD4
T26889	2922-2927	Protein	denotes	FOXP3
T26890	2972-2977	Protein	denotes	GATA3
T26891	2978-2988	Gene_expression	denotes	expression
T26892	3121-3124	Protein	denotes	CD4
T26893	3170-3175	Protein	denotes	GATA3
T26894	3188-3193	Protein	denotes	FOXP3
T26895	3332-3342	Protein	denotes	luciferase
T26896	3482-3487	Protein	denotes	GATA3
T26897	3708-3713	Protein	denotes	GATA3
T26898	3784-3789	Protein	denotes	GATA3
T26899	3950-3955	Protein	denotes	GATA3
T26900	3956-3963	Binding	denotes	binding
T26901	3971-3976	Protein	denotes	FOXP3
T26902	3977-3985	Entity	denotes	promoter
R8544	T11427	T11428	causeOf	GATA3,Represses
R8545	T11430	T11429	partOf	Promoter,FOXP3
R8546	T11430	T11428	themeOf	Promoter,Represses
R8547	T11431	T11433	causeOf	GATA3,repression
R8548	T11431	T11432	causeOf	GATA3,mediated
R8549	T11433	T11432	themeOf	repression,mediated
R8550	T11434	T11433	themeOf	FOXP3,repression
R8551	T11436	T11433	themeOf	promoter,repression
R8552	T11436	T11435	partOf	promoter,FOXP3
R8553	T11440	T11441	themeOf	FOXP3,regulation
R8554	T11445	T11444	themeOf	GATA3,express
R8555	T11447	T11446	partOf	promoter,FOXP3
R8556	T11448	T11449	themeOf	GATA3,expressing
R8557	T11452	T11451	themeOf	GATA3,express
R8558	T11454	T11453	themeOf	GATA3,Overexpression
R8559	T11457	T11456	partOf	promoter,FOXP3
R8560	T11459	T11458	themeOf	-binding site,deleting
R8561	T11468	T11467	partOf	promoter,FOXP3
R8562	T11469	T11470	themeOf	GATA3,binds
R8563	T11472	T11470	themeOf	promoter,binds
R8564	T11472	T11471	partOf	promoter,FOXP3
R8565	T11475	T11476	themeOf	GATA3,binding
R8566	T11477	T11478	themeOf	GATA3,expressing
R8567	T11480	T11479	themeOf	GATA3,overexpressing
R8568	T11481	T11482	themeOf	GATA3,binding
R8569	T11483	T11484	themeOf	GATA3,binds
R8570	T11486	T11484	themeOf	promoter,binds
R8571	T11486	T11485	partOf	promoter,FOXP3
R8572	T11488	T11489	themeOf	GATA3,binds
R8573	T11491	T11490	partOf	promoter,FOXP3
R8574	T11491	T11489	themeOf	promoter,binds
R8575	T11493	T11494	themeOf	GATA3,binding
R8576	T11494	T11497	causeOf	binding,repressing
R8577	T11496	T11494	themeOf	promoter,binding
R8578	T11496	T11495	partOf	promoter,FOXP3
R8579	T11498	T11499	themeOf	FOXP3,expression
R8580	T11499	T11497	themeOf	expression,repressing
R19803	T26880	T26881	causeOf	GATA3,Represses
R19804	T26883	T26881	themeOf	Promoter,Represses
R19805	T26883	T26882	partOf	Promoter,FOXP3
R19806	T26890	T26891	themeOf	GATA3,expression
R19807	T26899	T26900	themeOf	GATA3,binding
R19808	T26902	T26900	themeOf	promoter,binding
R19809	T26902	T26901	partOf	promoter,FOXP3

PMC:2222968 / 23457-27615 JSONTXT

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PMC:2222968 / 23457-27615 JSON TXT