PMC:2222968 / 20242-23455
Annnotations
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
18162042-9846495-84705020 | 359-360 | 9846495 | denotes | 2 |
18162042-12648458-84705021 | 361-363 | 12648458 | denotes | 21 |
18162042-11441076-84705022 | 1527-1529 | 11441076 | denotes | 22 |
18162042-9335507-84705023 | 2114-2116 | 9335507 | denotes | 23 |
T32923 | 359-360 | 9846495 | denotes | 2 |
T97991 | 361-363 | 12648458 | denotes | 21 |
T7965 | 1527-1529 | 11441076 | denotes | 22 |
T9118 | 2114-2116 | 9335507 | denotes | 23 |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9866 | 0-5 | NN | denotes | GATA3 |
T9867 | 6-8 | VB | denotes | Is |
T9868 | 9-10 | DT | denotes | a |
T9869 | 11-19 | JJ | denotes | Negative |
T9870 | 20-29 | NN | denotes | Regulator |
T9871 | 30-32 | IN | denotes | of |
T9872 | 33-38 | NN | denotes | FOXP3 |
T9873 | 39-49 | NN | denotes | Expression |
T9874 | 50-55 | NN | denotes | FOXP3 |
T9875 | 56-66 | NN | denotes | expression |
T9876 | 67-76 | VB | denotes | decreased |
T9877 | 77-81 | RB | denotes | once |
T9878 | 82-87 | NN | denotes | GATA3 |
T9879 | 88-98 | NN | denotes | expression |
T9880 | 99-101 | VB | denotes | is |
T9881 | 102-106 | JJ | denotes | high |
T9882 | 106-107 | -COLON- | denotes | ; |
T9883 | 108-117 | RB | denotes | therefore |
T9884 | 117-118 | -COMMA- | denotes | , |
T9885 | 119-121 | PRP | denotes | we |
T9886 | 122-134 | VB | denotes | hypothesized |
T9887 | 135-136 | DT | denotes | a |
T9888 | 137-146 | JJ | denotes | potential |
T9889 | 147-151 | NN | denotes | role |
T9890 | 152-155 | IN | denotes | for |
T9891 | 156-161 | NN | denotes | GATA3 |
T9892 | 162-164 | IN | denotes | in |
T9893 | 165-175 | VB | denotes | repressing |
T9894 | 176-181 | NN | denotes | FOXP3 |
T9895 | 183-190 | IN | denotes | Besides |
T9896 | 191-198 | NN | denotes | GATA3′s |
T9897 | 199-209 | JJ | denotes | well-known |
T9898 | 210-218 | JJ | denotes | positive |
T9899 | 219-225 | NN | denotes | effect |
T9900 | 226-228 | IN | denotes | on |
T9901 | 229-233 | NN | denotes | gene |
T9902 | 234-244 | NN | denotes | regulation |
T9903 | 244-245 | -COMMA- | denotes | , |
T9904 | 246-253 | NN | denotes | GATA3′s |
T9905 | 254-264 | JJ | denotes | repressive |
T9906 | 265-277 | NN | denotes | capabilities |
T9907 | 278-282 | VB | denotes | were |
T9908 | 283-293 | RB | denotes | previously |
T9909 | 294-299 | VB | denotes | shown |
T9910 | 300-302 | TO | denotes | to |
T9911 | 303-311 | VB | denotes | restrict |
T9912 | 312-315 | NN | denotes | Th1 |
T9913 | 316-326 | NN | denotes | commitment |
T9914 | 327-329 | IN | denotes | by |
T9915 | 330-340 | VB | denotes | inhibiting |
T9916 | 341-346 | NN | denotes | STAT4 |
T9917 | 347-357 | NN | denotes | expression |
T9918 | 358-359 | -LRB- | denotes | [ |
T9919 | 359-363 | CD | denotes | 2,21 |
T9920 | 363-364 | -RRB- | denotes | ] |
T9921 | 364-365 | -COMMA- | denotes | , |
T9922 | 366-369 | CC | denotes | and |
T9923 | 370-379 | RB | denotes | therefore |
T9924 | 380-385 | NN | denotes | GATA3 |
T9925 | 386-394 | VB | denotes | prevents |
T9926 | 395-410 | NN | denotes | differentiation |
T9927 | 411-415 | IN | denotes | into |
T9928 | 416-419 | NN | denotes | Th1 |
T9929 | 420-425 | NN | denotes | cells |
T9930 | 427-429 | TO | denotes | To |
T9931 | 430-441 | VB | denotes | investigate |
T9932 | 442-449 | IN | denotes | whether |
T9933 | 450-455 | NN | denotes | GATA3 |
T9934 | 456-459 | MD | denotes | can |
T9935 | 460-468 | RB | denotes | directly |
T9936 | 469-476 | VB | denotes | inhibit |
T9937 | 477-482 | NN | denotes | FOXP3 |
T9938 | 483-492 | NN | denotes | induction |
T9939 | 492-493 | -COMMA- | denotes | , |
T9940 | 494-496 | PRP | denotes | we |
T9941 | 497-507 | VB | denotes | transduced |
T9942 | 508-513 | NN | denotes | GATA3 |
T9943 | 514-516 | CC | denotes | or |
T9944 | 517-518 | DT | denotes | a |
T9945 | 519-528 | VB | denotes | truncated |
T9946 | 529-534 | NN | denotes | GATA3 |
T9947 | 535-542 | VB | denotes | lacking |
T9948 | 543-546 | DT | denotes | the |
T9949 | 547-558 | JJ | denotes | DNA-binding |
T9950 | 559-565 | NN | denotes | domain |
T9951 | 566-568 | IN | denotes | in |
T9952 | 569-574 | JJ | denotes | human |
T9953 | 575-582 | JJ | denotes | primary |
T9954 | 583-594 | JJ | denotes | CD4+CD45RA+ |
T9955 | 595-596 | NN | denotes | T |
T9956 | 597-602 | NN | denotes | cells |
T9957 | 603-608 | VB | denotes | using |
T9958 | 609-610 | DT | denotes | a |
T9959 | 611-620 | JJ | denotes | TAT-fused |
T9960 | 620-621 | -COMMA- | denotes | , |
T9961 | 622-635 | RB | denotes | recombinantly |
T9962 | 636-645 | VB | denotes | expressed |
T9963 | 646-651 | NN | denotes | GATA3 |
T9964 | 653-658 | IN | denotes | After |
T9965 | 659-671 | NN | denotes | transduction |
T9966 | 671-672 | -COMMA- | denotes | , |
T9967 | 673-676 | DT | denotes | the |
T9968 | 677-682 | NN | denotes | cells |
T9969 | 683-687 | VB | denotes | were |
T9970 | 688-697 | VB | denotes | activated |
T9971 | 698-702 | IN | denotes | with |
T9972 | 703-710 | JJ | denotes | soluble |
T9973 | 711-724 | NN | denotes | anti-CD3/CD28 |
T9974 | 725-727 | IN | denotes | in |
T9975 | 728-731 | DT | denotes | the |
T9976 | 732-740 | NN | denotes | presence |
T9977 | 741-743 | CC | denotes | or |
T9978 | 744-751 | NN | denotes | absence |
T9979 | 752-754 | IN | denotes | of |
T9980 | 755-760 | NN | denotes | TGF-β |
T9981 | 762-771 | NN | denotes | TAT-GATA3 |
T9982 | 772-775 | VB | denotes | was |
T9983 | 776-788 | RB | denotes | successfully |
T9984 | 789-799 | VB | denotes | transduced |
T9985 | 800-802 | IN | denotes | in |
T9986 | 803-804 | DT | denotes | a |
T9987 | 805-816 | JJ | denotes | homogeneous |
T9988 | 817-820 | CC | denotes | and |
T9989 | 821-835 | JJ | denotes | dose-dependent |
T9990 | 836-842 | NN | denotes | manner |
T9991 | 843-847 | IN | denotes | into |
T9992 | 848-853 | JJ | denotes | human |
T9993 | 854-858 | JJ | denotes | CD4+ |
T9994 | 859-860 | NN | denotes | T |
T9995 | 861-866 | NN | denotes | cells |
T9996 | 867-868 | -LRB- | denotes | ( |
T9997 | 868-874 | NNP | denotes | Figure |
T9998 | 875-877 | NNP | denotes | 7A |
T9999 | 877-878 | -COMMA- | denotes | , |
T10000 | 879-884 | JJ | denotes | upper |
T10001 | 885-890 | NN | denotes | panel |
T10002 | 890-891 | -RRB- | denotes | ) |
T10003 | 893-902 | NN | denotes | TAT-GATA3 |
T10004 | 903-910 | VB | denotes | reduced |
T10005 | 911-916 | NN | denotes | FOXP3 |
T10006 | 917-927 | NN | denotes | expression |
T10007 | 928-930 | IN | denotes | in |
T10008 | 931-932 | DT | denotes | a |
T10009 | 933-947 | JJ | denotes | dose-dependent |
T10010 | 948-954 | NN | denotes | manner |
T10011 | 954-955 | -COMMA- | denotes | , |
T10012 | 956-963 | IN | denotes | whereas |
T10013 | 964-965 | DT | denotes | a |
T10014 | 966-977 | JJ | denotes | DNA-binding |
T10015 | 978-984 | NN | denotes | domain |
T10016 | 985-994 | VB | denotes | truncated |
T10017 | 995-1002 | NN | denotes | version |
T10018 | 1003-1004 | -LRB- | denotes | ( |
T10019 | 1004-1018 | NN | denotes | TAT-ΔDBD-GATA3 |
T10020 | 1018-1019 | -RRB- | denotes | ) |
T10021 | 1020-1023 | VB | denotes | did |
T10022 | 1024-1027 | RB | denotes | not |
T10023 | 1028-1034 | VB | denotes | affect |
T10024 | 1035-1040 | NN | denotes | FOXP3 |
T10025 | 1041-1051 | NN | denotes | expression |
T10026 | 1052-1054 | IN | denotes | as |
T10027 | 1055-1063 | VB | denotes | compared |
T10028 | 1064-1068 | IN | denotes | with |
T10029 | 1069-1079 | NN | denotes | expression |
T10030 | 1080-1082 | IN | denotes | in |
T10031 | 1083-1095 | JJ | denotes | untransduced |
T10032 | 1096-1101 | NN | denotes | cells |
T10033 | 1102-1103 | -LRB- | denotes | ( |
T10034 | 1103-1109 | NN | denotes | Figure |
T10035 | 1110-1112 | NN | denotes | 7A |
T10036 | 1112-1113 | -RRB- | denotes | ) |
T10037 | 1115-1117 | IN | denotes | In |
T10038 | 1118-1126 | NN | denotes | addition |
T10039 | 1126-1127 | -COMMA- | denotes | , |
T10040 | 1128-1130 | PRP | denotes | we |
T10041 | 1131-1139 | VB | denotes | analyzed |
T10042 | 1140-1143 | DT | denotes | the |
T10043 | 1144-1154 | JJ | denotes | inhibitory |
T10044 | 1155-1161 | NN | denotes | effect |
T10045 | 1162-1164 | IN | denotes | of |
T10046 | 1165-1170 | NN | denotes | GATA3 |
T10047 | 1171-1173 | IN | denotes | on |
T10048 | 1174-1179 | NN | denotes | FOXP3 |
T10049 | 1180-1182 | IN | denotes | in |
T10050 | 1183-1193 | JJ | denotes | transgenic |
T10051 | 1194-1201 | NN | denotes | DO11.10 |
T10052 | 1202-1206 | NN | denotes | mice |
T10053 | 1206-1207 | -COMMA- | denotes | , |
T10054 | 1208-1222 | RB | denotes | constitutively |
T10055 | 1223-1237 | VB | denotes | overexpressing |
T10056 | 1238-1243 | NN | denotes | GATA3 |
T10057 | 1244-1249 | IN | denotes | under |
T10058 | 1250-1253 | DT | denotes | the |
T10059 | 1254-1261 | NN | denotes | control |
T10060 | 1262-1264 | IN | denotes | of |
T10061 | 1265-1268 | DT | denotes | the |
T10062 | 1269-1272 | NN | denotes | CD2 |
T10063 | 1273-1278 | NN | denotes | locus |
T10064 | 1279-1286 | NN | denotes | control |
T10065 | 1287-1293 | NN | denotes | region |
T10066 | 1294-1295 | -LRB- | denotes | ( |
T10067 | 1295-1312 | NN | denotes | DO11.10xCD2-GATA3 |
T10068 | 1312-1313 | -RRB- | denotes | ) |
T10069 | 1315-1318 | DT | denotes | The |
T10070 | 1319-1325 | JJ | denotes | thymic |
T10071 | 1326-1335 | NN | denotes | selection |
T10072 | 1336-1340 | IN | denotes | into |
T10073 | 1341-1344 | DT | denotes | the |
T10074 | 1345-1348 | NN | denotes | CD4 |
T10075 | 1349-1356 | NN | denotes | lineage |
T10076 | 1357-1359 | VB | denotes | is |
T10077 | 1360-1367 | RB | denotes | largely |
T10078 | 1368-1374 | JJ | denotes | intact |
T10079 | 1375-1377 | IN | denotes | in |
T10080 | 1378-1395 | NN | denotes | DO11.10xCD2-GATA3 |
T10081 | 1396-1397 | -LRB- | denotes | ( |
T10082 | 1397-1399 | NNP | denotes | RW |
T10083 | 1400-1408 | NNP | denotes | Hendriks |
T10084 | 1408-1409 | -COMMA- | denotes | , |
T10085 | 1410-1421 | JJ | denotes | unpublished |
T10086 | 1422-1426 | NN | denotes | data |
T10087 | 1426-1427 | -RRB- | denotes | ) |
T10088 | 1429-1434 | DT | denotes | These |
T10089 | 1435-1439 | NN | denotes | mice |
T10090 | 1440-1447 | VB | denotes | develop |
T10091 | 1448-1457 | NN | denotes | lymphomas |
T10092 | 1458-1460 | IN | denotes | at |
T10093 | 1461-1463 | DT | denotes | an |
T10094 | 1464-1469 | JJ | denotes | older |
T10095 | 1470-1473 | NN | denotes | age |
T10096 | 1473-1474 | -COMMA- | denotes | , |
T10097 | 1475-1478 | CC | denotes | but |
T10098 | 1479-1484 | NN | denotes | signs |
T10099 | 1485-1487 | IN | denotes | of |
T10100 | 1488-1498 | JJ | denotes | autoimmune |
T10101 | 1499-1506 | NN | denotes | disease |
T10102 | 1507-1511 | VB | denotes | were |
T10103 | 1512-1515 | RB | denotes | not |
T10104 | 1516-1525 | VB | denotes | described |
T10105 | 1526-1527 | -LRB- | denotes | [ |
T10106 | 1527-1529 | CD | denotes | 22 |
T10107 | 1529-1530 | -RRB- | denotes | ] |
T10108 | 1532-1534 | TO | denotes | To |
T10109 | 1535-1546 | VB | denotes | investigate |
T10110 | 1547-1550 | DT | denotes | the |
T10111 | 1551-1557 | NN | denotes | effect |
T10112 | 1558-1560 | IN | denotes | of |
T10113 | 1561-1566 | NN | denotes | GATA3 |
T10114 | 1567-1569 | IN | denotes | on |
T10115 | 1570-1575 | NN | denotes | iTreg |
T10116 | 1575-1576 | -COMMA- | denotes | , |
T10117 | 1577-1592 | NN | denotes | CD4+CD62L+CD25– |
T10118 | 1593-1598 | NN | denotes | cells |
T10119 | 1599-1603 | VB | denotes | were |
T10120 | 1604-1612 | VB | denotes | isolated |
T10121 | 1612-1613 | -COMMA- | denotes | , |
T10122 | 1614-1623 | VB | denotes | activated |
T10123 | 1624-1628 | IN | denotes | with |
T10124 | 1629-1632 | NN | denotes | OVA |
T10125 | 1633-1635 | IN | denotes | in |
T10126 | 1636-1639 | DT | denotes | the |
T10127 | 1640-1648 | NN | denotes | presence |
T10128 | 1649-1651 | CC | denotes | or |
T10129 | 1652-1659 | NN | denotes | absence |
T10130 | 1660-1662 | IN | denotes | of |
T10131 | 1663-1668 | NN | denotes | TGF-β |
T10132 | 1668-1669 | -COMMA- | denotes | , |
T10133 | 1670-1673 | CC | denotes | and |
T10134 | 1674-1679 | NN | denotes | Foxp3 |
T10135 | 1680-1690 | NN | denotes | expression |
T10136 | 1691-1694 | VB | denotes | was |
T10137 | 1695-1703 | VB | denotes | analyzed |
T10138 | 1704-1709 | IN | denotes | after |
T10139 | 1710-1711 | CD | denotes | 4 |
T10140 | 1712-1713 | NN | denotes | d |
T10141 | 1715-1718 | DT | denotes | The |
T10142 | 1719-1724 | JJ | denotes | naive |
T10143 | 1725-1734 | NN | denotes | CD4+CD25– |
T10144 | 1735-1740 | NN | denotes | cells |
T10145 | 1741-1745 | VB | denotes | were |
T10146 | 1746-1752 | CD | denotes | Foxp3– |
T10147 | 1753-1754 | -LRB- | denotes | ( |
T10148 | 1754-1765 | JJ | denotes | unpublished |
T10149 | 1766-1770 | NN | denotes | data |
T10150 | 1770-1771 | -RRB- | denotes | ) |
T10151 | 1773-1775 | IN | denotes | As |
T10152 | 1776-1785 | VB | denotes | described |
T10153 | 1786-1789 | IN | denotes | for |
T10154 | 1790-1793 | DT | denotes | the |
T10155 | 1794-1799 | JJ | denotes | human |
T10156 | 1800-1805 | NN | denotes | cells |
T10157 | 1805-1806 | -COMMA- | denotes | , |
T10158 | 1807-1812 | NN | denotes | TGF-β |
T10159 | 1813-1825 | RB | denotes | dramatically |
T10160 | 1826-1838 | VB | denotes | up-regulated |
T10161 | 1839-1844 | NN | denotes | Foxp3 |
T10162 | 1845-1847 | IN | denotes | in |
T10163 | 1848-1851 | DT | denotes | the |
T10164 | 1852-1859 | NN | denotes | DO11.10 |
T10165 | 1860-1870 | NN | denotes | littermate |
T10166 | 1871-1878 | NN | denotes | control |
T10167 | 1879-1883 | NN | denotes | mice |
T10168 | 1885-1887 | IN | denotes | In |
T10169 | 1888-1896 | NN | denotes | contrast |
T10170 | 1896-1897 | -COMMA- | denotes | , |
T10171 | 1898-1903 | NN | denotes | cells |
T10172 | 1904-1908 | IN | denotes | from |
T10173 | 1909-1912 | DT | denotes | the |
T10174 | 1913-1930 | NN | denotes | CD2-GATA3xDO11.10 |
T10175 | 1931-1935 | NN | denotes | mice |
T10176 | 1936-1942 | VB | denotes | showed |
T10177 | 1943-1955 | RB | denotes | dramatically |
T10178 | 1956-1963 | VB | denotes | reduced |
T10179 | 1964-1969 | NN | denotes | Foxp3 |
T10180 | 1970-1980 | NN | denotes | expression |
T10181 | 1981-1985 | WRB | denotes | when |
T10182 | 1986-1995 | VB | denotes | activated |
T10183 | 1996-2000 | IN | denotes | with |
T10184 | 2001-2006 | NN | denotes | TGF-β |
T10185 | 2007-2010 | CC | denotes | and |
T10186 | 2011-2014 | NN | denotes | OVA |
T10187 | 2015-2016 | -LRB- | denotes | ( |
T10188 | 2016-2022 | NN | denotes | Figure |
T10189 | 2023-2025 | NN | denotes | 7B |
T10190 | 2025-2026 | -RRB- | denotes | ) |
T10191 | 2028-2031 | DT | denotes | All |
T10192 | 2032-2036 | NN | denotes | mice |
T10193 | 2037-2045 | VB | denotes | produced |
T10194 | 2046-2053 | JJ | denotes | similar |
T10195 | 2054-2061 | NN | denotes | amounts |
T10196 | 2062-2064 | IN | denotes | of |
T10197 | 2065-2070 | NN | denotes | TGF-β |
T10198 | 2070-2071 | -COLON- | denotes | ; |
T10199 | 2072-2074 | IN | denotes | in |
T10200 | 2075-2083 | NN | denotes | addition |
T10201 | 2083-2084 | -COMMA- | denotes | , |
T10202 | 2085-2090 | NN | denotes | Smad7 |
T10203 | 2091-2094 | VB | denotes | was |
T10204 | 2095-2102 | RB | denotes | equally |
T10205 | 2103-2112 | VB | denotes | expressed |
T10206 | 2113-2114 | -LRB- | denotes | [ |
T10207 | 2114-2116 | CD | denotes | 23 |
T10208 | 2116-2117 | -RRB- | denotes | ] |
T10209 | 2118-2120 | IN | denotes | in |
T10210 | 2121-2122 | NN | denotes | T |
T10211 | 2123-2128 | NN | denotes | cells |
T10212 | 2129-2131 | IN | denotes | of |
T10213 | 2132-2136 | DT | denotes | both |
T10214 | 2137-2141 | NN | denotes | mice |
T10215 | 2142-2149 | NN | denotes | strains |
T10216 | 2150-2151 | -LRB- | denotes | ( |
T10217 | 2151-2157 | NN | denotes | Figure |
T10218 | 2158-2160 | NN | denotes | 7C |
T10219 | 2160-2161 | -RRB- | denotes | ) |
T10220 | 2161-2162 | -COMMA- | denotes | , |
T10221 | 2163-2173 | VB | denotes | indicating |
T10222 | 2174-2180 | JJ | denotes | intact |
T10223 | 2181-2186 | NN | denotes | TGF-β |
T10224 | 2187-2196 | NN | denotes | signaling |
T10225 | 3076-3081 | VB | denotes | Taken |
T10226 | 3082-3090 | RB | denotes | together |
T10227 | 3090-3091 | -COMMA- | denotes | , |
T10228 | 3092-3097 | DT | denotes | these |
T10229 | 3098-3105 | NN | denotes | results |
T10230 | 3106-3118 | VB | denotes | demonstrated |
T10231 | 3119-3120 | DT | denotes | a |
T10232 | 3121-3131 | JJ | denotes | repressive |
T10233 | 3132-3136 | NN | denotes | role |
T10234 | 3137-3139 | IN | denotes | of |
T10235 | 3140-3152 | JJ | denotes | IL-4-induced |
T10236 | 3153-3158 | NN | denotes | GATA3 |
T10237 | 3159-3172 | NN | denotes | transcription |
T10238 | 3173-3179 | NN | denotes | factor |
T10239 | 3180-3182 | IN | denotes | in |
T10240 | 3183-3186 | DT | denotes | the |
T10241 | 3187-3197 | NN | denotes | generation |
T10242 | 3198-3200 | IN | denotes | of |
T10243 | 3201-3206 | NN | denotes | iTreg |
T10244 | 3207-3212 | NN | denotes | cells |
T26347 | 2208-2213 | NN | denotes | GATA3 |
T26348 | 2214-2218 | VB | denotes | Acts |
T26349 | 2219-2221 | IN | denotes | as |
T26350 | 2222-2223 | DT | denotes | a |
T26351 | 2224-2232 | JJ | denotes | Negative |
T26352 | 2233-2242 | NN | denotes | Regulator |
T26353 | 2243-2245 | IN | denotes | of |
T26354 | 2246-2251 | NN | denotes | FOXP3 |
T26355 | 2252-2262 | NN | denotes | Expression |
T26356 | 2263-2264 | -LRB- | denotes | ( |
T26357 | 2264-2265 | NN | denotes | A |
T26358 | 2265-2266 | -RRB- | denotes | ) |
T26359 | 2267-2272 | JJ | denotes | Human |
T26360 | 2273-2278 | JJ | denotes | naive |
T26361 | 2279-2288 | JJ | denotes | CD4+CDRA+ |
T26362 | 2289-2290 | NN | denotes | T |
T26363 | 2291-2296 | NN | denotes | cells |
T26364 | 2297-2301 | VB | denotes | were |
T26365 | 2302-2312 | VB | denotes | transduced |
T26366 | 2313-2317 | IN | denotes | with |
T26367 | 2318-2319 | CD | denotes | 0 |
T26368 | 2319-2320 | -COMMA- | denotes | , |
T26369 | 2321-2323 | CD | denotes | 20 |
T26370 | 2323-2324 | -COMMA- | denotes | , |
T26371 | 2325-2328 | CD | denotes | 100 |
T26372 | 2328-2329 | -COMMA- | denotes | , |
T26373 | 2330-2333 | CC | denotes | and |
T26374 | 2334-2337 | CD | denotes | 500 |
T26375 | 2338-2340 | NN | denotes | nM |
T26376 | 2341-2343 | IN | denotes | of |
T26377 | 2344-2353 | NN | denotes | TAT-GATA3 |
T26378 | 2354-2361 | NN | denotes | protein |
T26379 | 2361-2362 | -COMMA- | denotes | , |
T26380 | 2363-2366 | CC | denotes | and |
T26381 | 2367-2380 | JJ | denotes | intracellular |
T26382 | 2381-2389 | NN | denotes | presence |
T26383 | 2390-2392 | IN | denotes | of |
T26384 | 2393-2398 | NN | denotes | GATA3 |
T26385 | 2399-2402 | VB | denotes | was |
T26386 | 2403-2411 | VB | denotes | analyzed |
T26387 | 2412-2417 | VB | denotes | using |
T26388 | 2418-2422 | NN | denotes | FACS |
T26389 | 2423-2432 | VB | denotes | following |
T26390 | 2433-2446 | JJ | denotes | anti-CD3/CD28 |
T26391 | 2447-2457 | NN | denotes | activation |
T26392 | 2458-2460 | IN | denotes | of |
T26393 | 2461-2464 | DT | denotes | the |
T26394 | 2465-2470 | NN | denotes | cells |
T26395 | 2472-2484 | JJ | denotes | GFP-positive |
T26396 | 2485-2490 | NN | denotes | cells |
T26397 | 2491-2495 | VB | denotes | were |
T26398 | 2496-2501 | VB | denotes | gated |
T26399 | 2502-2505 | CC | denotes | and |
T26400 | 2506-2514 | VB | denotes | analyzed |
T26401 | 2515-2518 | IN | denotes | for |
T26402 | 2519-2532 | JJ | denotes | intracellular |
T26403 | 2533-2538 | NN | denotes | FOXP3 |
T26404 | 2539-2549 | NN | denotes | expression |
T26405 | 2550-2559 | VB | denotes | following |
T26406 | 2560-2561 | DT | denotes | a |
T26407 | 2562-2565 | JJ | denotes | 2-d |
T26408 | 2566-2576 | NN | denotes | incubation |
T26409 | 2577-2583 | NN | denotes | period |
T26410 | 2584-2585 | -LRB- | denotes | ( |
T26411 | 2585-2590 | JJ | denotes | lower |
T26412 | 2591-2596 | NN | denotes | panel |
T26413 | 2596-2597 | -RRB- | denotes | ) |
T26414 | 2599-2603 | NN | denotes | Data |
T26415 | 2604-2607 | VB | denotes | are |
T26416 | 2608-2622 | JJ | denotes | representative |
T26417 | 2623-2625 | IN | denotes | of |
T26418 | 2626-2630 | CD | denotes | four |
T26419 | 2631-2642 | JJ | denotes | independent |
T26420 | 2643-2654 | NN | denotes | experiments |
T26421 | 2656-2657 | -LRB- | denotes | ( |
T26422 | 2657-2658 | NN | denotes | B |
T26423 | 2658-2659 | -RRB- | denotes | ) |
T26424 | 2660-2669 | NN | denotes | CD4+CD25− |
T26425 | 2670-2671 | NN | denotes | T |
T26426 | 2672-2677 | NN | denotes | cells |
T26427 | 2678-2682 | VB | denotes | were |
T26428 | 2683-2691 | VB | denotes | isolated |
T26429 | 2692-2696 | IN | denotes | from |
T26430 | 2697-2704 | NN | denotes | D011.10 |
T26431 | 2705-2708 | CC | denotes | and |
T26432 | 2709-2726 | NN | denotes | D011.10xCD2-GATA3 |
T26433 | 2727-2731 | NN | denotes | mice |
T26434 | 2732-2735 | CC | denotes | and |
T26435 | 2736-2743 | VB | denotes | treated |
T26436 | 2744-2748 | IN | denotes | with |
T26437 | 2749-2752 | NN | denotes | OVA |
T26438 | 2753-2756 | CC | denotes | and |
T26439 | 2757-2762 | NN | denotes | TGF-β |
T26440 | 2763-2766 | IN | denotes | for |
T26441 | 2767-2769 | CD | denotes | 96 |
T26442 | 2770-2771 | NN | denotes | h |
T26443 | 2773-2780 | NN | denotes | Surface |
T26444 | 2781-2784 | NN | denotes | CD4 |
T26445 | 2785-2788 | CC | denotes | and |
T26446 | 2789-2802 | JJ | denotes | intracellular |
T26447 | 2803-2808 | NN | denotes | FOXP3 |
T26448 | 2809-2813 | VB | denotes | were |
T26449 | 2814-2822 | VB | denotes | measured |
T26450 | 2823-2825 | IN | denotes | by |
T26451 | 2826-2830 | NN | denotes | FACS |
T26452 | 2832-2837 | DT | denotes | These |
T26453 | 2838-2842 | NN | denotes | data |
T26454 | 2843-2846 | VB | denotes | are |
T26455 | 2847-2861 | JJ | denotes | representative |
T26456 | 2862-2864 | IN | denotes | of |
T26457 | 2865-2870 | CD | denotes | three |
T26458 | 2871-2882 | JJ | denotes | independent |
T26459 | 2883-2894 | NN | denotes | experiments |
T26460 | 2896-2897 | -LRB- | denotes | ( |
T26461 | 2897-2898 | NN | denotes | C |
T26462 | 2898-2899 | -RRB- | denotes | ) |
T26463 | 2900-2903 | DT | denotes | The |
T26464 | 2904-2909 | NN | denotes | cells |
T26465 | 2910-2917 | VB | denotes | treated |
T26466 | 2918-2920 | IN | denotes | as |
T26467 | 2921-2923 | IN | denotes | in |
T26468 | 2924-2925 | -LRB- | denotes | ( |
T26469 | 2925-2926 | NN | denotes | B |
T26470 | 2926-2927 | -RRB- | denotes | ) |
T26471 | 2928-2932 | VB | denotes | were |
T26472 | 2933-2942 | VB | denotes | harvested |
T26473 | 2943-2946 | CC | denotes | and |
T26474 | 2947-2951 | NN | denotes | mRNA |
T26475 | 2952-2955 | VB | denotes | was |
T26476 | 2956-2966 | VB | denotes | quantified |
T26477 | 2967-2969 | IN | denotes | by |
T26478 | 2970-2979 | JJ | denotes | real-time |
T26479 | 2980-2983 | NN | denotes | PCR |
T26480 | 2984-2987 | IN | denotes | for |
T26481 | 2988-2993 | NN | denotes | SMAD7 |
T26482 | 2994-2997 | CC | denotes | and |
T26483 | 2998-3003 | NN | denotes | TGF-β |
T26484 | 3004-3014 | NN | denotes | expression |
T26485 | 3016-3020 | NN | denotes | Bars |
T26486 | 3021-3025 | VB | denotes | show |
T26487 | 3026-3029 | DT | denotes | the |
T26488 | 3030-3034 | JJ | denotes | mean |
T26489 | 3035-3036 | JJ | denotes | ± |
T26490 | 3037-3039 | NN | denotes | SD |
T26491 | 3040-3042 | IN | denotes | of |
T26492 | 3043-3048 | CD | denotes | three |
T26493 | 3049-3060 | JJ | denotes | independent |
T26494 | 3061-3072 | NN | denotes | experiments |
R7423 | T9866 | T9867 | arg1Of | GATA3,Is |
R7424 | T9870 | T9867 | arg2Of | Regulator,Is |
R7425 | T9870 | T9868 | arg1Of | Regulator,a |
R7426 | T9870 | T9869 | arg1Of | Regulator,Negative |
R7427 | T9870 | T9871 | arg1Of | Regulator,of |
R7428 | T9873 | T9871 | arg2Of | Expression,of |
R7429 | T9873 | T9872 | arg1Of | Expression,FOXP3 |
R7430 | T9875 | T9874 | arg1Of | expression,FOXP3 |
R7431 | T9875 | T9876 | arg1Of | expression,decreased |
R7432 | T9876 | T9877 | arg1Of | decreased,once |
R7433 | T9876 | T9882 | arg1Of | decreased,; |
R7434 | T9879 | T9878 | arg1Of | expression,GATA3 |
R7435 | T9879 | T9880 | arg1Of | expression,is |
R7436 | T9879 | T9881 | arg1Of | expression,high |
R7437 | T9880 | T9877 | arg2Of | is,once |
R7438 | T9881 | T9880 | arg2Of | high,is |
R7439 | T9885 | T9886 | arg1Of | we,hypothesized |
R7440 | T9886 | T9882 | arg2Of | hypothesized,; |
R7441 | T9886 | T9883 | arg1Of | hypothesized,therefore |
R7442 | T9886 | T9884 | arg1Of | hypothesized,"," |
R7443 | T9889 | T9886 | arg2Of | role,hypothesized |
R7444 | T9889 | T9887 | arg1Of | role,a |
R7445 | T9889 | T9888 | arg1Of | role,potential |
R7446 | T9889 | T9890 | arg1Of | role,for |
R7447 | T9889 | T9892 | arg1Of | role,in |
R7448 | T9891 | T9890 | arg2Of | GATA3,for |
R7449 | T9893 | T9892 | arg2Of | repressing,in |
R7450 | T9894 | T9893 | arg2Of | FOXP3,repressing |
R7451 | T9898 | T9897 | arg1Of | positive,well-known |
R7452 | T9899 | T9895 | arg2Of | effect,Besides |
R7453 | T9899 | T9896 | arg1Of | effect,GATA3′s |
R7454 | T9899 | T9898 | arg1Of | effect,positive |
R7455 | T9899 | T9900 | arg1Of | effect,on |
R7456 | T9902 | T9900 | arg2Of | regulation,on |
R7457 | T9902 | T9901 | arg1Of | regulation,gene |
R7458 | T9906 | T9904 | arg1Of | capabilities,GATA3′s |
R7459 | T9906 | T9905 | arg1Of | capabilities,repressive |
R7460 | T9906 | T9907 | arg1Of | capabilities,were |
R7461 | T9906 | T9909 | arg2Of | capabilities,shown |
R7462 | T9906 | T9911 | arg1Of | capabilities,restrict |
R7463 | T9906 | T9915 | arg1Of | capabilities,inhibiting |
R7464 | T9909 | T9907 | arg2Of | shown,were |
R7465 | T9909 | T9908 | arg1Of | shown,previously |
R7466 | T9909 | T9922 | arg1Of | shown,and |
R7467 | T9911 | T9909 | arg3Of | restrict,shown |
R7468 | T9911 | T9910 | arg1Of | restrict,to |
R7469 | T9911 | T9914 | arg1Of | restrict,by |
R7470 | T9913 | T9911 | arg2Of | commitment,restrict |
R7471 | T9913 | T9912 | arg1Of | commitment,Th1 |
R7472 | T9915 | T9914 | arg2Of | inhibiting,by |
R7473 | T9917 | T9915 | arg2Of | expression,inhibiting |
R7474 | T9917 | T9916 | arg1Of | expression,STAT4 |
R7475 | T9917 | T9918 | arg1Of | expression,[ |
R7476 | T9919 | T9918 | arg2Of | "2,21",[ |
R7477 | T9920 | T9918 | arg3Of | ],[ |
R7478 | T9922 | T9895 | arg1Of | and,Besides |
R7479 | T9922 | T9903 | arg1Of | and,"," |
R7480 | T9922 | T9921 | arg1Of | and,"," |
R7481 | T9924 | T9923 | arg1Of | GATA3,therefore |
R7482 | T9924 | T9925 | arg1Of | GATA3,prevents |
R7483 | T9925 | T9922 | arg2Of | prevents,and |
R7484 | T9926 | T9925 | arg2Of | differentiation,prevents |
R7485 | T9926 | T9927 | arg1Of | differentiation,into |
R7486 | T9929 | T9927 | arg2Of | cells,into |
R7487 | T9929 | T9928 | arg1Of | cells,Th1 |
R7488 | T9931 | T9930 | arg1Of | investigate,To |
R7489 | T9933 | T9934 | arg1Of | GATA3,can |
R7490 | T9933 | T9936 | arg1Of | GATA3,inhibit |
R7491 | T9936 | T9931 | arg2Of | inhibit,investigate |
R7492 | T9936 | T9932 | arg1Of | inhibit,whether |
R7493 | T9936 | T9934 | arg2Of | inhibit,can |
R7494 | T9936 | T9935 | arg1Of | inhibit,directly |
R7495 | T9938 | T9936 | arg2Of | induction,inhibit |
R7496 | T9938 | T9937 | arg1Of | induction,FOXP3 |
R7497 | T9940 | T9931 | arg1Of | we,investigate |
R7498 | T9940 | T9941 | arg1Of | we,transduced |
R7499 | T9941 | T9930 | modOf | transduced,To |
R7500 | T9941 | T9939 | arg1Of | transduced,"," |
R7501 | T9941 | T9951 | arg1Of | transduced,in |
R7502 | T9942 | T9943 | arg1Of | GATA3,or |
R7503 | T9943 | T9941 | arg2Of | or,transduced |
R7504 | T9946 | T9943 | arg2Of | GATA3,or |
R7505 | T9946 | T9944 | arg1Of | GATA3,a |
R7506 | T9946 | T9945 | arg2Of | GATA3,truncated |
R7507 | T9946 | T9947 | arg1Of | GATA3,lacking |
R7508 | T9950 | T9947 | arg2Of | domain,lacking |
R7509 | T9950 | T9948 | arg1Of | domain,the |
R7510 | T9950 | T9949 | arg1Of | domain,DNA-binding |
R7511 | T9956 | T9951 | arg2Of | cells,in |
R7512 | T9956 | T9952 | arg1Of | cells,human |
R7513 | T9956 | T9953 | arg1Of | cells,primary |
R7514 | T9956 | T9954 | arg1Of | cells,CD4+CD45RA+ |
R7515 | T9956 | T9955 | arg1Of | cells,T |
R7516 | T9956 | T9957 | arg1Of | cells,using |
R7517 | T9959 | T9960 | arg1Of | TAT-fused,"," |
R7518 | T9962 | T9960 | arg2Of | expressed,"," |
R7519 | T9962 | T9961 | arg1Of | expressed,recombinantly |
R7520 | T9963 | T9957 | arg2Of | GATA3,using |
R7521 | T9963 | T9958 | arg1Of | GATA3,a |
R7522 | T9963 | T9959 | arg1Of | GATA3,TAT-fused |
R7523 | T9963 | T9962 | arg1Of | GATA3,expressed |
R7524 | T9965 | T9964 | arg2Of | transduction,After |
R7525 | T9968 | T9967 | arg1Of | cells,the |
R7526 | T9968 | T9969 | arg1Of | cells,were |
R7527 | T9968 | T9970 | arg2Of | cells,activated |
R7528 | T9970 | T9964 | arg1Of | activated,After |
R7529 | T9970 | T9966 | arg1Of | activated,"," |
R7530 | T9970 | T9969 | arg2Of | activated,were |
R7531 | T9970 | T9971 | arg1Of | activated,with |
R7532 | T9970 | T9974 | arg1Of | activated,in |
R7533 | T9973 | T9971 | arg2Of | anti-CD3/CD28,with |
R7534 | T9973 | T9972 | arg1Of | anti-CD3/CD28,soluble |
R7535 | T9976 | T9977 | arg1Of | presence,or |
R7536 | T9977 | T9974 | arg2Of | or,in |
R7537 | T9977 | T9975 | arg1Of | or,the |
R7538 | T9977 | T9979 | arg1Of | or,of |
R7539 | T9978 | T9977 | arg2Of | absence,or |
R7540 | T9980 | T9979 | arg2Of | TGF-β,of |
R7541 | T9981 | T9982 | arg1Of | TAT-GATA3,was |
R7542 | T9981 | T9984 | arg2Of | TAT-GATA3,transduced |
R7543 | T9984 | T9982 | arg2Of | transduced,was |
R7544 | T9984 | T9983 | arg1Of | transduced,successfully |
R7545 | T9984 | T9985 | arg1Of | transduced,in |
R7546 | T9984 | T9991 | arg1Of | transduced,into |
R7547 | T9987 | T9988 | arg1Of | homogeneous,and |
R7548 | T9989 | T9988 | arg2Of | dose-dependent,and |
R7549 | T9990 | T9985 | arg2Of | manner,in |
R7550 | T9990 | T9986 | arg1Of | manner,a |
R7551 | T9990 | T9987 | arg1Of | manner,homogeneous |
R7552 | T9990 | T9989 | arg1Of | manner,dose-dependent |
R7553 | T9995 | T9991 | arg2Of | cells,into |
R7554 | T9995 | T9992 | arg1Of | cells,human |
R7555 | T9995 | T9993 | arg1Of | cells,CD4+ |
R7556 | T9995 | T9994 | arg1Of | cells,T |
R7557 | T9995 | T9996 | arg1Of | cells,( |
R7558 | T9998 | T9996 | arg2Of | 7A,( |
R7559 | T9998 | T9997 | arg1Of | 7A,Figure |
R7560 | T9998 | T9999 | arg1Of | 7A,"," |
R7561 | T10001 | T9999 | arg2Of | panel,"," |
R7562 | T10001 | T10000 | arg1Of | panel,upper |
R7563 | T10002 | T9996 | arg3Of | ),( |
R7564 | T10003 | T10004 | arg1Of | TAT-GATA3,reduced |
R7565 | T10004 | T10007 | arg1Of | reduced,in |
R7566 | T10004 | T10011 | arg1Of | reduced,"," |
R7567 | T10004 | T10012 | arg1Of | reduced,whereas |
R7568 | T10006 | T10004 | arg2Of | expression,reduced |
R7569 | T10006 | T10005 | arg1Of | expression,FOXP3 |
R7570 | T10010 | T10007 | arg2Of | manner,in |
R7571 | T10010 | T10008 | arg1Of | manner,a |
R7572 | T10010 | T10009 | arg1Of | manner,dose-dependent |
R7573 | T10017 | T10013 | arg1Of | version,a |
R7574 | T10017 | T10014 | arg1Of | version,DNA-binding |
R7575 | T10017 | T10015 | arg1Of | version,domain |
R7576 | T10017 | T10016 | arg2Of | version,truncated |
R7577 | T10017 | T10018 | arg1Of | version,( |
R7578 | T10017 | T10021 | arg1Of | version,did |
R7579 | T10017 | T10023 | arg1Of | version,affect |
R7580 | T10019 | T10018 | arg2Of | TAT-ΔDBD-GATA3,( |
R7581 | T10020 | T10018 | arg3Of | ),( |
R7582 | T10023 | T10012 | arg2Of | affect,whereas |
R7583 | T10023 | T10021 | arg2Of | affect,did |
R7584 | T10023 | T10022 | arg1Of | affect,not |
R7585 | T10023 | T10026 | arg1Of | affect,as |
R7586 | T10025 | T10023 | arg2Of | expression,affect |
R7587 | T10025 | T10024 | arg1Of | expression,FOXP3 |
R7588 | T10027 | T10026 | arg2Of | compared,as |
R7589 | T10027 | T10028 | arg1Of | compared,with |
R7590 | T10029 | T10028 | arg2Of | expression,with |
R7591 | T10029 | T10030 | arg1Of | expression,in |
R7592 | T10032 | T10030 | arg2Of | cells,in |
R7593 | T10032 | T10031 | arg1Of | cells,untransduced |
R7594 | T10032 | T10033 | arg1Of | cells,( |
R7595 | T10035 | T10033 | arg2Of | 7A,( |
R7596 | T10035 | T10034 | arg1Of | 7A,Figure |
R7597 | T10036 | T10033 | arg3Of | ),( |
R7598 | T10038 | T10037 | arg2Of | addition,In |
R7599 | T10040 | T10041 | arg1Of | we,analyzed |
R7600 | T10040 | T10055 | arg1Of | we,overexpressing |
R7601 | T10041 | T10037 | arg1Of | analyzed,In |
R7602 | T10041 | T10039 | arg1Of | analyzed,"," |
R7603 | T10041 | T10053 | arg1Of | analyzed,"," |
R7604 | T10041 | T10055 | modOf | analyzed,overexpressing |
R7605 | T10044 | T10041 | arg2Of | effect,analyzed |
R7606 | T10044 | T10042 | arg1Of | effect,the |
R7607 | T10044 | T10043 | arg1Of | effect,inhibitory |
R7608 | T10044 | T10045 | arg1Of | effect,of |
R7609 | T10044 | T10047 | arg1Of | effect,on |
R7610 | T10046 | T10045 | arg2Of | GATA3,of |
R7611 | T10048 | T10047 | arg2Of | FOXP3,on |
R7612 | T10048 | T10049 | arg1Of | FOXP3,in |
R7613 | T10052 | T10049 | arg2Of | mice,in |
R7614 | T10052 | T10050 | arg1Of | mice,transgenic |
R7615 | T10052 | T10051 | arg1Of | mice,DO11.10 |
R7616 | T10055 | T10054 | arg1Of | overexpressing,constitutively |
R7617 | T10055 | T10057 | arg1Of | overexpressing,under |
R7618 | T10056 | T10055 | arg2Of | GATA3,overexpressing |
R7619 | T10059 | T10057 | arg2Of | control,under |
R7620 | T10059 | T10058 | arg1Of | control,the |
R7621 | T10059 | T10060 | arg1Of | control,of |
R7622 | T10065 | T10060 | arg2Of | region,of |
R7623 | T10065 | T10061 | arg1Of | region,the |
R7624 | T10065 | T10062 | arg1Of | region,CD2 |
R7625 | T10065 | T10063 | arg1Of | region,locus |
R7626 | T10065 | T10064 | arg1Of | region,control |
R7627 | T10065 | T10066 | arg1Of | region,( |
R7628 | T10067 | T10066 | arg2Of | DO11.10xCD2-GATA3,( |
R7629 | T10068 | T10066 | arg3Of | ),( |
R7630 | T10071 | T10069 | arg1Of | selection,The |
R7631 | T10071 | T10070 | arg1Of | selection,thymic |
R7632 | T10071 | T10072 | arg1Of | selection,into |
R7633 | T10071 | T10076 | arg1Of | selection,is |
R7634 | T10071 | T10078 | arg1Of | selection,intact |
R7635 | T10075 | T10072 | arg2Of | lineage,into |
R7636 | T10075 | T10073 | arg1Of | lineage,the |
R7637 | T10075 | T10074 | arg1Of | lineage,CD4 |
R7638 | T10076 | T10081 | arg1Of | is,( |
R7639 | T10078 | T10076 | arg2Of | intact,is |
R7640 | T10078 | T10077 | arg1Of | intact,largely |
R7641 | T10078 | T10079 | arg1Of | intact,in |
R7642 | T10080 | T10079 | arg2Of | DO11.10xCD2-GATA3,in |
R7643 | T10083 | T10081 | arg2Of | Hendriks,( |
R7644 | T10083 | T10082 | arg1Of | Hendriks,RW |
R7645 | T10083 | T10084 | arg1Of | Hendriks,"," |
R7646 | T10086 | T10084 | arg2Of | data,"," |
R7647 | T10086 | T10085 | arg1Of | data,unpublished |
R7648 | T10087 | T10081 | arg3Of | ),( |
R7649 | T10089 | T10088 | arg1Of | mice,These |
R7650 | T10089 | T10090 | arg1Of | mice,develop |
R7651 | T10090 | T10092 | arg1Of | develop,at |
R7652 | T10090 | T10097 | arg1Of | develop,but |
R7653 | T10091 | T10090 | arg2Of | lymphomas,develop |
R7654 | T10095 | T10092 | arg2Of | age,at |
R7655 | T10095 | T10093 | arg1Of | age,an |
R7656 | T10095 | T10094 | arg1Of | age,older |
R7657 | T10097 | T10096 | arg1Of | but,"," |
R7658 | T10098 | T10099 | arg1Of | signs,of |
R7659 | T10098 | T10102 | arg1Of | signs,were |
R7660 | T10098 | T10104 | arg2Of | signs,described |
R7661 | T10101 | T10099 | arg2Of | disease,of |
R7662 | T10101 | T10100 | arg1Of | disease,autoimmune |
R7663 | T10104 | T10097 | arg2Of | described,but |
R7664 | T10104 | T10102 | arg2Of | described,were |
R7665 | T10104 | T10103 | arg1Of | described,not |
R7666 | T10104 | T10105 | arg1Of | described,[ |
R7667 | T10106 | T10105 | arg2Of | 22,[ |
R7668 | T10107 | T10105 | arg3Of | ],[ |
R7669 | T10109 | T10108 | arg1Of | investigate,To |
R7670 | T10111 | T10109 | arg2Of | effect,investigate |
R7671 | T10111 | T10110 | arg1Of | effect,the |
R7672 | T10111 | T10112 | arg1Of | effect,of |
R7673 | T10111 | T10114 | arg1Of | effect,on |
R7674 | T10113 | T10112 | arg2Of | GATA3,of |
R7675 | T10115 | T10114 | arg2Of | iTreg,on |
R7676 | T10118 | T10109 | arg1Of | cells,investigate |
R7677 | T10118 | T10117 | arg1Of | cells,CD4+CD62L+CD25– |
R7678 | T10118 | T10119 | arg1Of | cells,were |
R7679 | T10118 | T10120 | arg2Of | cells,isolated |
R7680 | T10118 | T10122 | arg2Of | cells,activated |
R7681 | T10120 | T10121 | arg1Of | isolated,"," |
R7682 | T10121 | T10119 | arg2Of | ",",were |
R7683 | T10121 | T10133 | arg1Of | ",",and |
R7684 | T10122 | T10121 | arg2Of | activated,"," |
R7685 | T10122 | T10123 | arg1Of | activated,with |
R7686 | T10122 | T10125 | arg1Of | activated,in |
R7687 | T10124 | T10123 | arg2Of | OVA,with |
R7688 | T10127 | T10128 | arg1Of | presence,or |
R7689 | T10128 | T10125 | arg2Of | or,in |
R7690 | T10128 | T10126 | arg1Of | or,the |
R7691 | T10128 | T10130 | arg1Of | or,of |
R7692 | T10129 | T10128 | arg2Of | absence,or |
R7693 | T10131 | T10130 | arg2Of | TGF-β,of |
R7694 | T10133 | T10108 | modOf | and,To |
R7695 | T10133 | T10116 | arg1Of | and,"," |
R7696 | T10133 | T10132 | arg1Of | and,"," |
R7697 | T10135 | T10134 | arg1Of | expression,Foxp3 |
R7698 | T10135 | T10136 | arg1Of | expression,was |
R7699 | T10135 | T10137 | arg2Of | expression,analyzed |
R7700 | T10137 | T10133 | arg2Of | analyzed,and |
R7701 | T10137 | T10136 | arg2Of | analyzed,was |
R7702 | T10137 | T10138 | arg1Of | analyzed,after |
R7703 | T10140 | T10138 | arg2Of | d,after |
R7704 | T10140 | T10139 | arg1Of | d,4 |
R7705 | T10144 | T10141 | arg1Of | cells,The |
R7706 | T10144 | T10142 | arg1Of | cells,naive |
R7707 | T10144 | T10143 | arg1Of | cells,CD4+CD25– |
R7708 | T10144 | T10145 | arg1Of | cells,were |
R7709 | T10146 | T10145 | arg2Of | Foxp3–,were |
R7710 | T10146 | T10147 | arg1Of | Foxp3–,( |
R7711 | T10149 | T10147 | arg2Of | data,( |
R7712 | T10149 | T10148 | arg1Of | data,unpublished |
R7713 | T10150 | T10147 | arg3Of | ),( |
R7714 | T10152 | T10151 | arg2Of | described,As |
R7715 | T10152 | T10153 | arg1Of | described,for |
R7716 | T10156 | T10153 | arg2Of | cells,for |
R7717 | T10156 | T10154 | arg1Of | cells,the |
R7718 | T10156 | T10155 | arg1Of | cells,human |
R7719 | T10158 | T10160 | arg1Of | TGF-β,up-regulated |
R7720 | T10160 | T10151 | arg1Of | up-regulated,As |
R7721 | T10160 | T10157 | arg1Of | up-regulated,"," |
R7722 | T10160 | T10159 | arg1Of | up-regulated,dramatically |
R7723 | T10160 | T10162 | arg1Of | up-regulated,in |
R7724 | T10161 | T10160 | arg2Of | Foxp3,up-regulated |
R7725 | T10167 | T10162 | arg2Of | mice,in |
R7726 | T10167 | T10163 | arg1Of | mice,the |
R7727 | T10167 | T10164 | arg1Of | mice,DO11.10 |
R7728 | T10167 | T10165 | arg1Of | mice,littermate |
R7729 | T10167 | T10166 | arg1Of | mice,control |
R7730 | T10169 | T10168 | arg2Of | contrast,In |
R7731 | T10171 | T10172 | arg1Of | cells,from |
R7732 | T10171 | T10176 | arg1Of | cells,showed |
R7733 | T10175 | T10172 | arg2Of | mice,from |
R7734 | T10175 | T10173 | arg1Of | mice,the |
R7735 | T10175 | T10174 | arg1Of | mice,CD2-GATA3xDO11.10 |
R7736 | T10176 | T10168 | arg1Of | showed,In |
R7737 | T10176 | T10170 | arg1Of | showed,"," |
R7738 | T10176 | T10181 | arg1Of | showed,when |
R7739 | T10178 | T10177 | arg1Of | reduced,dramatically |
R7740 | T10180 | T10176 | arg2Of | expression,showed |
R7741 | T10180 | T10178 | arg1Of | expression,reduced |
R7742 | T10180 | T10179 | arg1Of | expression,Foxp3 |
R7743 | T10182 | T10181 | arg2Of | activated,when |
R7744 | T10182 | T10183 | arg1Of | activated,with |
R7745 | T10184 | T10185 | arg1Of | TGF-β,and |
R7746 | T10185 | T10183 | arg2Of | and,with |
R7747 | T10185 | T10187 | arg1Of | and,( |
R7748 | T10186 | T10185 | arg2Of | OVA,and |
R7749 | T10189 | T10187 | arg2Of | 7B,( |
R7750 | T10189 | T10188 | arg1Of | 7B,Figure |
R7751 | T10190 | T10187 | arg3Of | ),( |
R7752 | T10192 | T10191 | arg1Of | mice,All |
R7753 | T10192 | T10193 | arg1Of | mice,produced |
R7754 | T10193 | T10198 | arg1Of | produced,; |
R7755 | T10195 | T10193 | arg2Of | amounts,produced |
R7756 | T10195 | T10194 | arg1Of | amounts,similar |
R7757 | T10195 | T10196 | arg1Of | amounts,of |
R7758 | T10197 | T10196 | arg2Of | TGF-β,of |
R7759 | T10200 | T10199 | arg2Of | addition,in |
R7760 | T10202 | T10203 | arg1Of | Smad7,was |
R7761 | T10202 | T10205 | arg2Of | Smad7,expressed |
R7762 | T10205 | T10198 | arg2Of | expressed,; |
R7763 | T10205 | T10199 | arg1Of | expressed,in |
R7764 | T10205 | T10201 | arg1Of | expressed,"," |
R7765 | T10205 | T10203 | arg2Of | expressed,was |
R7766 | T10205 | T10204 | arg1Of | expressed,equally |
R7767 | T10205 | T10206 | arg1Of | expressed,[ |
R7768 | T10205 | T10209 | arg1Of | expressed,in |
R7769 | T10205 | T10220 | arg1Of | expressed,"," |
R7770 | T10205 | T10221 | modOf | expressed,indicating |
R7771 | T10207 | T10206 | arg2Of | 23,[ |
R7772 | T10208 | T10206 | arg3Of | ],[ |
R7773 | T10211 | T10209 | arg2Of | cells,in |
R7774 | T10211 | T10210 | arg1Of | cells,T |
R7775 | T10211 | T10212 | arg1Of | cells,of |
R7776 | T10215 | T10212 | arg2Of | strains,of |
R7777 | T10215 | T10213 | arg1Of | strains,both |
R7778 | T10215 | T10214 | arg1Of | strains,mice |
R7779 | T10215 | T10216 | arg1Of | strains,( |
R7780 | T10218 | T10216 | arg2Of | 7C,( |
R7781 | T10218 | T10217 | arg1Of | 7C,Figure |
R7782 | T10219 | T10216 | arg3Of | ),( |
R7783 | T10224 | T10221 | arg2Of | signaling,indicating |
R7784 | T10224 | T10222 | arg1Of | signaling,intact |
R7785 | T10224 | T10223 | arg1Of | signaling,TGF-β |
R7786 | T10225 | T10226 | arg1Of | Taken,together |
R7787 | T10229 | T10228 | arg1Of | results,these |
R7788 | T10229 | T10230 | arg1Of | results,demonstrated |
R7789 | T10230 | T10225 | modOf | demonstrated,Taken |
R7790 | T10230 | T10227 | arg1Of | demonstrated,"," |
R7791 | T10233 | T10230 | arg2Of | role,demonstrated |
R7792 | T10233 | T10231 | arg1Of | role,a |
R7793 | T10233 | T10232 | arg1Of | role,repressive |
R7794 | T10233 | T10234 | arg1Of | role,of |
R7795 | T10233 | T10239 | arg1Of | role,in |
R7796 | T10238 | T10234 | arg2Of | factor,of |
R7797 | T10238 | T10235 | arg1Of | factor,IL-4-induced |
R7798 | T10238 | T10236 | arg1Of | factor,GATA3 |
R7799 | T10238 | T10237 | arg1Of | factor,transcription |
R7800 | T10241 | T10239 | arg2Of | generation,in |
R7801 | T10241 | T10240 | arg1Of | generation,the |
R7802 | T10241 | T10242 | arg1Of | generation,of |
R7803 | T10244 | T10242 | arg2Of | cells,of |
R7804 | T10244 | T10243 | arg1Of | cells,iTreg |
R19451 | T26347 | T26348 | arg1Of | GATA3,Acts |
R19452 | T26348 | T26349 | arg1Of | Acts,as |
R19453 | T26352 | T26349 | arg2Of | Regulator,as |
R19454 | T26352 | T26350 | arg1Of | Regulator,a |
R19455 | T26352 | T26351 | arg1Of | Regulator,Negative |
R19456 | T26352 | T26353 | arg1Of | Regulator,of |
R19457 | T26355 | T26353 | arg2Of | Expression,of |
R19458 | T26355 | T26354 | arg1Of | Expression,FOXP3 |
R19459 | T26357 | T26356 | arg2Of | A,( |
R19460 | T26358 | T26356 | arg3Of | ),( |
R19461 | T26363 | T26356 | arg1Of | cells,( |
R19462 | T26363 | T26359 | arg1Of | cells,Human |
R19463 | T26363 | T26360 | arg1Of | cells,naive |
R19464 | T26363 | T26361 | arg1Of | cells,CD4+CDRA+ |
R19465 | T26363 | T26362 | arg1Of | cells,T |
R19466 | T26363 | T26364 | arg1Of | cells,were |
R19467 | T26363 | T26365 | arg2Of | cells,transduced |
R19468 | T26365 | T26364 | arg2Of | transduced,were |
R19469 | T26365 | T26366 | arg1Of | transduced,with |
R19470 | T26365 | T26380 | arg1Of | transduced,and |
R19471 | T26367 | T26368 | arg1Of | 0,"," |
R19472 | T26368 | T26370 | arg1Of | ",","," |
R19473 | T26369 | T26368 | arg2Of | 20,"," |
R19474 | T26370 | T26373 | arg1Of | ",",and |
R19475 | T26371 | T26370 | arg2Of | 100,"," |
R19476 | T26373 | T26366 | arg2Of | and,with |
R19477 | T26373 | T26372 | arg1Of | and,"," |
R19478 | T26375 | T26373 | arg2Of | nM,and |
R19479 | T26375 | T26374 | arg1Of | nM,500 |
R19480 | T26375 | T26376 | arg1Of | nM,of |
R19481 | T26378 | T26376 | arg2Of | protein,of |
R19482 | T26378 | T26377 | arg1Of | protein,TAT-GATA3 |
R19483 | T26380 | T26379 | arg1Of | and,"," |
R19484 | T26382 | T26381 | arg1Of | presence,intracellular |
R19485 | T26382 | T26383 | arg1Of | presence,of |
R19486 | T26382 | T26385 | arg1Of | presence,was |
R19487 | T26382 | T26386 | arg2Of | presence,analyzed |
R19488 | T26384 | T26383 | arg2Of | GATA3,of |
R19489 | T26386 | T26380 | arg2Of | analyzed,and |
R19490 | T26386 | T26385 | arg2Of | analyzed,was |
R19491 | T26387 | T26386 | arg3Of | using,analyzed |
R19492 | T26387 | T26389 | arg1Of | using,following |
R19493 | T26388 | T26387 | arg2Of | FACS,using |
R19494 | T26391 | T26389 | arg2Of | activation,following |
R19495 | T26391 | T26390 | arg1Of | activation,anti-CD3/CD28 |
R19496 | T26391 | T26392 | arg1Of | activation,of |
R19497 | T26394 | T26392 | arg2Of | cells,of |
R19498 | T26394 | T26393 | arg1Of | cells,the |
R19499 | T26396 | T26395 | arg1Of | cells,GFP-positive |
R19500 | T26396 | T26397 | arg1Of | cells,were |
R19501 | T26396 | T26398 | arg2Of | cells,gated |
R19502 | T26396 | T26400 | arg2Of | cells,analyzed |
R19503 | T26398 | T26399 | arg1Of | gated,and |
R19504 | T26399 | T26397 | arg2Of | and,were |
R19505 | T26400 | T26399 | arg2Of | analyzed,and |
R19506 | T26400 | T26401 | arg1Of | analyzed,for |
R19507 | T26400 | T26405 | arg1Of | analyzed,following |
R19508 | T26404 | T26401 | arg2Of | expression,for |
R19509 | T26404 | T26402 | arg1Of | expression,intracellular |
R19510 | T26404 | T26403 | arg1Of | expression,FOXP3 |
R19511 | T26409 | T26405 | arg2Of | period,following |
R19512 | T26409 | T26406 | arg1Of | period,a |
R19513 | T26409 | T26407 | arg1Of | period,2-d |
R19514 | T26409 | T26408 | arg1Of | period,incubation |
R19515 | T26409 | T26410 | arg1Of | period,( |
R19516 | T26412 | T26410 | arg2Of | panel,( |
R19517 | T26412 | T26411 | arg1Of | panel,lower |
R19518 | T26413 | T26410 | arg3Of | ),( |
R19519 | T26414 | T26415 | arg1Of | Data,are |
R19520 | T26414 | T26416 | arg1Of | Data,representative |
R19521 | T26416 | T26415 | arg2Of | representative,are |
R19522 | T26416 | T26417 | arg1Of | representative,of |
R19523 | T26420 | T26417 | arg2Of | experiments,of |
R19524 | T26420 | T26418 | arg1Of | experiments,four |
R19525 | T26420 | T26419 | arg1Of | experiments,independent |
R19526 | T26422 | T26421 | arg2Of | B,( |
R19527 | T26423 | T26421 | arg3Of | ),( |
R19528 | T26426 | T26421 | arg1Of | cells,( |
R19529 | T26426 | T26424 | arg1Of | cells,CD4+CD25− |
R19530 | T26426 | T26425 | arg1Of | cells,T |
R19531 | T26426 | T26427 | arg1Of | cells,were |
R19532 | T26426 | T26428 | arg2Of | cells,isolated |
R19533 | T26426 | T26435 | arg2Of | cells,treated |
R19534 | T26428 | T26429 | arg1Of | isolated,from |
R19535 | T26428 | T26434 | arg1Of | isolated,and |
R19536 | T26430 | T26431 | arg1Of | D011.10,and |
R19537 | T26432 | T26431 | arg2Of | D011.10xCD2-GATA3,and |
R19538 | T26433 | T26429 | arg2Of | mice,from |
R19539 | T26433 | T26430 | arg1Of | mice,D011.10 |
R19540 | T26433 | T26432 | arg1Of | mice,D011.10xCD2-GATA3 |
R19541 | T26434 | T26427 | arg2Of | and,were |
R19542 | T26435 | T26434 | arg2Of | treated,and |
R19543 | T26435 | T26436 | arg1Of | treated,with |
R19544 | T26435 | T26440 | arg1Of | treated,for |
R19545 | T26437 | T26438 | arg1Of | OVA,and |
R19546 | T26438 | T26436 | arg2Of | and,with |
R19547 | T26439 | T26438 | arg2Of | TGF-β,and |
R19548 | T26442 | T26440 | arg2Of | h,for |
R19549 | T26442 | T26441 | arg1Of | h,96 |
R19550 | T26444 | T26443 | arg1Of | CD4,Surface |
R19551 | T26444 | T26445 | arg1Of | CD4,and |
R19552 | T26445 | T26448 | arg1Of | and,were |
R19553 | T26445 | T26449 | arg2Of | and,measured |
R19554 | T26447 | T26445 | arg2Of | FOXP3,and |
R19555 | T26447 | T26446 | arg1Of | FOXP3,intracellular |
R19556 | T26449 | T26448 | arg2Of | measured,were |
R19557 | T26451 | T26449 | arg1Of | FACS,measured |
R19558 | T26451 | T26450 | arg2Of | FACS,by |
R19559 | T26453 | T26452 | arg1Of | data,These |
R19560 | T26453 | T26454 | arg1Of | data,are |
R19561 | T26453 | T26455 | arg1Of | data,representative |
R19562 | T26455 | T26454 | arg2Of | representative,are |
R19563 | T26455 | T26456 | arg1Of | representative,of |
R19564 | T26459 | T26456 | arg2Of | experiments,of |
R19565 | T26459 | T26457 | arg1Of | experiments,three |
R19566 | T26459 | T26458 | arg1Of | experiments,independent |
R19567 | T26461 | T26462 | arg1Of | C,) |
R19568 | T26464 | T26461 | arg1Of | cells,C |
R19569 | T26464 | T26463 | arg1Of | cells,The |
R19570 | T26464 | T26465 | arg2Of | cells,treated |
R19571 | T26464 | T26471 | arg1Of | cells,were |
R19572 | T26464 | T26472 | arg2Of | cells,harvested |
R19573 | T26465 | T26467 | arg1Of | treated,in |
R19574 | T26467 | T26466 | arg1Of | in,as |
R19575 | T26469 | T26467 | arg2Of | B,in |
R19576 | T26469 | T26468 | arg2Of | B,( |
R19577 | T26470 | T26468 | arg3Of | ),( |
R19578 | T26472 | T26471 | arg2Of | harvested,were |
R19579 | T26472 | T26473 | arg1Of | harvested,and |
R19580 | T26473 | T26460 | arg1Of | and,( |
R19581 | T26474 | T26475 | arg1Of | mRNA,was |
R19582 | T26474 | T26476 | arg2Of | mRNA,quantified |
R19583 | T26476 | T26473 | arg2Of | quantified,and |
R19584 | T26476 | T26475 | arg2Of | quantified,was |
R19585 | T26479 | T26476 | arg1Of | PCR,quantified |
R19586 | T26479 | T26477 | arg2Of | PCR,by |
R19587 | T26479 | T26478 | arg1Of | PCR,real-time |
R19588 | T26479 | T26480 | arg1Of | PCR,for |
R19589 | T26481 | T26482 | arg1Of | SMAD7,and |
R19590 | T26483 | T26482 | arg2Of | TGF-β,and |
R19591 | T26484 | T26480 | arg2Of | expression,for |
R19592 | T26484 | T26481 | arg1Of | expression,SMAD7 |
R19593 | T26484 | T26483 | arg1Of | expression,TGF-β |
R19594 | T26485 | T26486 | arg1Of | Bars,show |
R19595 | T26490 | T26486 | arg2Of | SD,show |
R19596 | T26490 | T26487 | arg1Of | SD,the |
R19597 | T26490 | T26488 | arg1Of | SD,mean |
R19598 | T26490 | T26489 | arg1Of | SD,± |
R19599 | T26490 | T26491 | arg1Of | SD,of |
R19600 | T26494 | T26491 | arg2Of | experiments,of |
R19601 | T26494 | T26492 | arg1Of | experiments,three |
R19602 | T26494 | T26493 | arg1Of | experiments,independent |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10333 | 0-5 | CD | denotes | GATA3 |
T10334 | 6-8 | VBZ | denotes | Is |
T10335 | 9-10 | DT | denotes | a |
T10336 | 11-19 | JJ | denotes | Negative |
T10337 | 20-29 | NNP | denotes | Regulator |
T10338 | 30-32 | IN | denotes | of |
T10339 | 33-38 | NNP | denotes | FOXP3 |
T10340 | 39-49 | NNP | denotes | Expression |
T10341 | 50-55 | NNP | denotes | FOXP3 |
T10342 | 56-66 | NN | denotes | expression |
T10343 | 67-76 | VBD | denotes | decreased |
T10344 | 77-81 | RB | denotes | once |
T10345 | 82-87 | JJ | denotes | GATA3 |
T10346 | 88-98 | NN | denotes | expression |
T10347 | 99-101 | VBZ | denotes | is |
T10348 | 102-106 | JJ | denotes | high |
T10349 | 106-107 | : | denotes | ; |
T10350 | 108-117 | RB | denotes | therefore |
T10351 | 117-118 | , | denotes | , |
T10352 | 119-121 | PRP | denotes | we |
T10353 | 122-134 | VBD | denotes | hypothesized |
T10354 | 135-136 | DT | denotes | a |
T10355 | 137-146 | JJ | denotes | potential |
T10356 | 147-151 | NN | denotes | role |
T10357 | 152-155 | IN | denotes | for |
T10358 | 156-161 | NNP | denotes | GATA3 |
T10359 | 162-164 | IN | denotes | in |
T10360 | 165-175 | VBG | denotes | repressing |
T10361 | 176-181 | NNP | denotes | FOXP3 |
T10362 | 181-182 | . | denotes | . |
T10363 | 183-190 | IN | denotes | Besides |
T10364 | 191-196 | NNP | denotes | GATA3 |
T10365 | 196-197 | NNP | denotes | ′ |
T10366 | 197-198 | VBZ | denotes | s |
T10367 | 199-209 | JJ | denotes | well-known |
T10368 | 210-218 | JJ | denotes | positive |
T10369 | 219-225 | NN | denotes | effect |
T10370 | 226-228 | IN | denotes | on |
T10371 | 229-233 | NN | denotes | gene |
T10372 | 234-244 | NN | denotes | regulation |
T10373 | 244-245 | , | denotes | , |
T10374 | 246-251 | NNP | denotes | GATA3 |
T10375 | 251-252 | NNP | denotes | ′ |
T10376 | 252-253 | VBZ | denotes | s |
T10377 | 254-264 | JJ | denotes | repressive |
T10378 | 265-277 | NNS | denotes | capabilities |
T10379 | 278-282 | VBD | denotes | were |
T10380 | 283-293 | RB | denotes | previously |
T10381 | 294-299 | VBN | denotes | shown |
T10382 | 300-302 | TO | denotes | to |
T10383 | 303-311 | VB | denotes | restrict |
T10384 | 312-315 | JJ | denotes | Th1 |
T10385 | 316-326 | NN | denotes | commitment |
T10386 | 327-329 | IN | denotes | by |
T10387 | 330-340 | VBG | denotes | inhibiting |
T10388 | 341-346 | NNP | denotes | STAT4 |
T10389 | 347-357 | NN | denotes | expression |
T10390 | 358-359 | NNP | denotes | [ |
T10391 | 359-363 | CD | denotes | 2,21 |
T10392 | 363-364 | NNP | denotes | ] |
T10393 | 364-365 | , | denotes | , |
T10394 | 366-369 | CC | denotes | and |
T10395 | 370-379 | RB | denotes | therefore |
T10396 | 380-385 | JJ | denotes | GATA3 |
T10397 | 386-394 | VBZ | denotes | prevents |
T10398 | 395-410 | NN | denotes | differentiation |
T10399 | 411-415 | IN | denotes | into |
T10400 | 416-419 | JJ | denotes | Th1 |
T10401 | 420-425 | NNS | denotes | cells |
T10402 | 425-426 | . | denotes | . |
T10403 | 427-429 | TO | denotes | To |
T10404 | 430-441 | VB | denotes | investigate |
T10405 | 442-449 | IN | denotes | whether |
T10406 | 450-455 | NNP | denotes | GATA3 |
T10407 | 456-459 | MD | denotes | can |
T10408 | 460-468 | RB | denotes | directly |
T10409 | 469-476 | VB | denotes | inhibit |
T10410 | 477-482 | CD | denotes | FOXP3 |
T10411 | 483-492 | NN | denotes | induction |
T10412 | 492-493 | , | denotes | , |
T10413 | 494-496 | PRP | denotes | we |
T10414 | 497-507 | VBD | denotes | transduced |
T10415 | 508-513 | NNP | denotes | GATA3 |
T10416 | 514-516 | CC | denotes | or |
T10417 | 517-518 | DT | denotes | a |
T10418 | 519-528 | VBN | denotes | truncated |
T10419 | 529-534 | NNP | denotes | GATA3 |
T10420 | 535-542 | VBG | denotes | lacking |
T10421 | 543-546 | DT | denotes | the |
T10422 | 547-558 | JJ | denotes | DNA-binding |
T10423 | 559-565 | NN | denotes | domain |
T10424 | 566-568 | IN | denotes | in |
T10425 | 569-574 | JJ | denotes | human |
T10426 | 575-582 | JJ | denotes | primary |
T10427 | 583-586 | NNP | denotes | CD4 |
T10428 | 586-587 | NNP | denotes | + |
T10429 | 587-593 | NNP | denotes | CD45RA |
T10430 | 593-594 | VBD | denotes | + |
T10431 | 595-596 | NNP | denotes | T |
T10432 | 597-602 | NNS | denotes | cells |
T10433 | 603-608 | VBG | denotes | using |
T10434 | 609-610 | DT | denotes | a |
T10435 | 611-620 | JJ | denotes | TAT-fused |
T10436 | 620-621 | , | denotes | , |
T10437 | 622-635 | RB | denotes | recombinantly |
T10438 | 636-645 | VBN | denotes | expressed |
T10439 | 646-651 | NNP | denotes | GATA3 |
T10440 | 651-652 | . | denotes | . |
T10441 | 653-658 | IN | denotes | After |
T10442 | 659-671 | NN | denotes | transduction |
T10443 | 671-672 | , | denotes | , |
T10444 | 673-676 | DT | denotes | the |
T10445 | 677-682 | NNS | denotes | cells |
T10446 | 683-687 | VBD | denotes | were |
T10447 | 688-697 | VBN | denotes | activated |
T10448 | 698-702 | IN | denotes | with |
T10449 | 703-710 | JJ | denotes | soluble |
T10450 | 711-719 | JJ | denotes | anti-CD3 |
T10451 | 719-720 | NN | denotes | / |
T10452 | 720-724 | CD | denotes | CD28 |
T10453 | 725-727 | IN | denotes | in |
T10454 | 728-731 | DT | denotes | the |
T10455 | 732-740 | NN | denotes | presence |
T10456 | 741-743 | CC | denotes | or |
T10457 | 744-751 | NN | denotes | absence |
T10458 | 752-754 | IN | denotes | of |
T10459 | 755-760 | NNP | denotes | TGF-β |
T10460 | 760-761 | . | denotes | . |
T10461 | 762-771 | CD | denotes | TAT-GATA3 |
T10462 | 772-775 | VBD | denotes | was |
T10463 | 776-788 | RB | denotes | successfully |
T10464 | 789-799 | VBN | denotes | transduced |
T10465 | 800-802 | IN | denotes | in |
T10466 | 803-804 | DT | denotes | a |
T10467 | 805-816 | JJ | denotes | homogeneous |
T10468 | 817-820 | CC | denotes | and |
T10469 | 821-835 | JJ | denotes | dose-dependent |
T10470 | 836-842 | NN | denotes | manner |
T10471 | 843-847 | IN | denotes | into |
T10472 | 848-853 | JJ | denotes | human |
T10473 | 854-857 | NNP | denotes | CD4 |
T10474 | 857-858 | CD | denotes | + |
T10475 | 859-860 | NNP | denotes | T |
T10476 | 861-866 | NNS | denotes | cells |
T10477 | 867-868 | -LRB- | denotes | ( |
T10478 | 868-874 | NN | denotes | Figure |
T10479 | 875-877 | NN | denotes | 7A |
T10480 | 877-878 | , | denotes | , |
T10481 | 879-884 | JJ | denotes | upper |
T10482 | 885-890 | NN | denotes | panel |
T10483 | 890-891 | -RRB- | denotes | ) |
T10484 | 891-892 | . | denotes | . |
T10485 | 893-902 | CD | denotes | TAT-GATA3 |
T10486 | 903-910 | VBN | denotes | reduced |
T10487 | 911-916 | CD | denotes | FOXP3 |
T10488 | 917-927 | NN | denotes | expression |
T10489 | 928-930 | IN | denotes | in |
T10490 | 931-932 | DT | denotes | a |
T10491 | 933-947 | JJ | denotes | dose-dependent |
T10492 | 948-954 | NN | denotes | manner |
T10493 | 954-955 | , | denotes | , |
T10494 | 956-963 | IN | denotes | whereas |
T10495 | 964-965 | DT | denotes | a |
T10496 | 966-977 | JJ | denotes | DNA-binding |
T10497 | 978-984 | NN | denotes | domain |
T10498 | 985-994 | VBN | denotes | truncated |
T10499 | 995-1002 | NN | denotes | version |
T10500 | 1003-1004 | -LRB- | denotes | ( |
T10501 | 1004-1018 | CD | denotes | TAT-ΔDBD-GATA3 |
T10502 | 1018-1019 | -RRB- | denotes | ) |
T10503 | 1020-1023 | VBD | denotes | did |
T10504 | 1024-1027 | RB | denotes | not |
T10505 | 1028-1034 | VB | denotes | affect |
T10506 | 1035-1040 | CD | denotes | FOXP3 |
T10507 | 1041-1051 | NN | denotes | expression |
T10508 | 1052-1054 | IN | denotes | as |
T10509 | 1055-1063 | VBN | denotes | compared |
T10510 | 1064-1068 | IN | denotes | with |
T10511 | 1069-1079 | NN | denotes | expression |
T10512 | 1080-1082 | IN | denotes | in |
T10513 | 1083-1095 | JJ | denotes | untransduced |
T10514 | 1096-1101 | NNS | denotes | cells |
T10515 | 1102-1103 | -LRB- | denotes | ( |
T10516 | 1103-1109 | NN | denotes | Figure |
T10517 | 1110-1112 | NN | denotes | 7A |
T10518 | 1112-1113 | -RRB- | denotes | ) |
T10519 | 1113-1114 | . | denotes | . |
T10520 | 1115-1117 | IN | denotes | In |
T10521 | 1118-1126 | NN | denotes | addition |
T10522 | 1126-1127 | , | denotes | , |
T10523 | 1128-1130 | PRP | denotes | we |
T10524 | 1131-1139 | VBD | denotes | analyzed |
T10525 | 1140-1143 | DT | denotes | the |
T10526 | 1144-1154 | JJ | denotes | inhibitory |
T10527 | 1155-1161 | NN | denotes | effect |
T10528 | 1162-1164 | IN | denotes | of |
T10529 | 1165-1170 | CD | denotes | GATA3 |
T10530 | 1171-1173 | IN | denotes | on |
T10531 | 1174-1179 | CD | denotes | FOXP3 |
T10532 | 1180-1182 | IN | denotes | in |
T10533 | 1183-1193 | JJ | denotes | transgenic |
T10534 | 1194-1198 | NNP | denotes | DO11 |
T10535 | 1198-1201 | CD | denotes | .10 |
T10536 | 1202-1206 | NNS | denotes | mice |
T10537 | 1206-1207 | , | denotes | , |
T10538 | 1208-1222 | RB | denotes | constitutively |
T10539 | 1223-1237 | VBG | denotes | overexpressing |
T10540 | 1238-1243 | NNP | denotes | GATA3 |
T10541 | 1244-1249 | IN | denotes | under |
T10542 | 1250-1253 | DT | denotes | the |
T10543 | 1254-1261 | NN | denotes | control |
T10544 | 1262-1264 | IN | denotes | of |
T10545 | 1265-1268 | DT | denotes | the |
T10546 | 1269-1272 | NNP | denotes | CD2 |
T10547 | 1273-1278 | NN | denotes | locus |
T10548 | 1279-1286 | NN | denotes | control |
T10549 | 1287-1293 | NN | denotes | region |
T10550 | 1294-1295 | -LRB- | denotes | ( |
T10551 | 1295-1312 | JJ | denotes | DO11.10xCD2-GATA3 |
T10552 | 1312-1313 | -RRB- | denotes | ) |
T10553 | 1313-1314 | . | denotes | . |
T10554 | 1315-1318 | DT | denotes | The |
T10555 | 1319-1325 | JJ | denotes | thymic |
T10556 | 1326-1335 | NN | denotes | selection |
T10557 | 1336-1340 | IN | denotes | into |
T10558 | 1341-1344 | DT | denotes | the |
T10559 | 1345-1348 | NNP | denotes | CD4 |
T10560 | 1349-1356 | NN | denotes | lineage |
T10561 | 1357-1359 | VBZ | denotes | is |
T10562 | 1360-1367 | RB | denotes | largely |
T10563 | 1368-1374 | JJ | denotes | intact |
T10564 | 1375-1377 | IN | denotes | in |
T10565 | 1378-1395 | NNP | denotes | DO11.10xCD2-GATA3 |
T10566 | 1396-1397 | -LRB- | denotes | ( |
T10567 | 1397-1399 | NNP | denotes | RW |
T10568 | 1400-1408 | NNPS | denotes | Hendriks |
T10569 | 1408-1409 | , | denotes | , |
T10570 | 1410-1421 | JJ | denotes | unpublished |
T10571 | 1422-1426 | NNS | denotes | data |
T10572 | 1426-1427 | -RRB- | denotes | ) |
T10573 | 1427-1428 | . | denotes | . |
T10574 | 1429-1434 | DT | denotes | These |
T10575 | 1435-1439 | NNS | denotes | mice |
T10576 | 1440-1447 | VBP | denotes | develop |
T10577 | 1448-1457 | NNS | denotes | lymphomas |
T10578 | 1458-1460 | IN | denotes | at |
T10579 | 1461-1463 | DT | denotes | an |
T10580 | 1464-1469 | JJR | denotes | older |
T10581 | 1470-1473 | NN | denotes | age |
T10582 | 1473-1474 | , | denotes | , |
T10583 | 1475-1478 | CC | denotes | but |
T10584 | 1479-1484 | NNS | denotes | signs |
T10585 | 1485-1487 | IN | denotes | of |
T10586 | 1488-1498 | JJ | denotes | autoimmune |
T10587 | 1499-1506 | NN | denotes | disease |
T10588 | 1507-1511 | VBD | denotes | were |
T10589 | 1512-1515 | RB | denotes | not |
T10590 | 1516-1525 | VBN | denotes | described |
T10591 | 1526-1527 | NNP | denotes | [ |
T10592 | 1527-1529 | CD | denotes | 22 |
T10593 | 1529-1530 | NNP | denotes | ] |
T10594 | 1530-1531 | . | denotes | . |
T10595 | 1532-1534 | TO | denotes | To |
T10596 | 1535-1546 | VB | denotes | investigate |
T10597 | 1547-1550 | DT | denotes | the |
T10598 | 1551-1557 | NN | denotes | effect |
T10599 | 1558-1560 | IN | denotes | of |
T10600 | 1561-1566 | NNP | denotes | GATA3 |
T10601 | 1567-1569 | IN | denotes | on |
T10602 | 1570-1575 | NNP | denotes | iTreg |
T10603 | 1575-1576 | , | denotes | , |
T10604 | 1577-1580 | NNP | denotes | CD4 |
T10605 | 1580-1581 | NNP | denotes | + |
T10606 | 1581-1586 | NNP | denotes | CD62L |
T10607 | 1586-1587 | NNP | denotes | + |
T10608 | 1587-1591 | NNP | denotes | CD25 |
T10609 | 1593-1598 | NNS | denotes | cells |
T10610 | 1599-1603 | VBD | denotes | were |
T10611 | 1604-1612 | VBN | denotes | isolated |
T10612 | 1612-1613 | , | denotes | , |
T10613 | 1614-1623 | VBN | denotes | activated |
T10614 | 1624-1628 | IN | denotes | with |
T10615 | 1629-1632 | NNP | denotes | OVA |
T10616 | 1633-1635 | IN | denotes | in |
T10617 | 1636-1639 | DT | denotes | the |
T10618 | 1640-1648 | NN | denotes | presence |
T10619 | 1649-1651 | CC | denotes | or |
T10620 | 1652-1659 | NN | denotes | absence |
T10621 | 1660-1662 | IN | denotes | of |
T10622 | 1663-1668 | NNP | denotes | TGF-β |
T10623 | 1668-1669 | , | denotes | , |
T10624 | 1670-1673 | CC | denotes | and |
T10625 | 1674-1679 | JJ | denotes | Foxp3 |
T10626 | 1680-1690 | NN | denotes | expression |
T10627 | 1691-1694 | VBD | denotes | was |
T10628 | 1695-1703 | VBN | denotes | analyzed |
T10629 | 1704-1709 | IN | denotes | after |
T10630 | 1710-1711 | CD | denotes | 4 |
T10631 | 1712-1713 | LS | denotes | d |
T10632 | 1713-1714 | . | denotes | . |
T10633 | 1715-1718 | DT | denotes | The |
T10634 | 1719-1724 | JJ | denotes | naive |
T10635 | 1725-1728 | NNP | denotes | CD4 |
T10636 | 1728-1729 | NNP | denotes | + |
T10637 | 1729-1733 | NNP | denotes | CD25 |
T10638 | 1735-1740 | NNS | denotes | cells |
T10639 | 1741-1745 | VBD | denotes | were |
T10640 | 1746-1751 | JJ | denotes | Foxp3 |
T10641 | 1753-1754 | -LRB- | denotes | ( |
T10642 | 1754-1765 | JJ | denotes | unpublished |
T10643 | 1766-1770 | NNS | denotes | data |
T10644 | 1770-1771 | -RRB- | denotes | ) |
T10645 | 1771-1772 | . | denotes | . |
T10646 | 1773-1775 | IN | denotes | As |
T10647 | 1776-1785 | VBN | denotes | described |
T10648 | 1786-1789 | IN | denotes | for |
T10649 | 1790-1793 | DT | denotes | the |
T10650 | 1794-1799 | JJ | denotes | human |
T10651 | 1800-1805 | NNS | denotes | cells |
T10652 | 1805-1806 | , | denotes | , |
T10653 | 1807-1812 | JJ | denotes | TGF-β |
T10654 | 1813-1825 | RB | denotes | dramatically |
T10655 | 1826-1838 | JJ | denotes | up-regulated |
T10656 | 1839-1844 | NN | denotes | Foxp3 |
T10657 | 1845-1847 | IN | denotes | in |
T10658 | 1848-1851 | DT | denotes | the |
T10659 | 1852-1856 | NNP | denotes | DO11 |
T10660 | 1856-1859 | CD | denotes | .10 |
T10661 | 1860-1870 | NN | denotes | littermate |
T10662 | 1871-1878 | NN | denotes | control |
T10663 | 1879-1883 | NNS | denotes | mice |
T10664 | 1883-1884 | . | denotes | . |
T10665 | 1885-1887 | IN | denotes | In |
T10666 | 1888-1896 | NN | denotes | contrast |
T10667 | 1896-1897 | , | denotes | , |
T10668 | 1898-1903 | NNS | denotes | cells |
T10669 | 1904-1908 | IN | denotes | from |
T10670 | 1909-1912 | DT | denotes | the |
T10671 | 1913-1927 | NNP | denotes | CD2-GATA3xDO11 |
T10672 | 1927-1930 | CD | denotes | .10 |
T10673 | 1931-1935 | NNS | denotes | mice |
T10674 | 1936-1942 | VBD | denotes | showed |
T10675 | 1943-1955 | RB | denotes | dramatically |
T10676 | 1956-1963 | VBN | denotes | reduced |
T10677 | 1964-1969 | JJ | denotes | Foxp3 |
T10678 | 1970-1980 | NN | denotes | expression |
T10679 | 1981-1985 | WRB | denotes | when |
T10680 | 1986-1995 | VBN | denotes | activated |
T10681 | 1996-2000 | IN | denotes | with |
T10682 | 2001-2006 | NNP | denotes | TGF-β |
T10683 | 2007-2010 | CC | denotes | and |
T10684 | 2011-2014 | NNP | denotes | OVA |
T10685 | 2015-2016 | -LRB- | denotes | ( |
T10686 | 2016-2022 | NNP | denotes | Figure |
T10687 | 2023-2025 | NN | denotes | 7B |
T10688 | 2025-2026 | -RRB- | denotes | ) |
T10689 | 2026-2027 | . | denotes | . |
T10690 | 2028-2031 | DT | denotes | All |
T10691 | 2032-2036 | NNS | denotes | mice |
T10692 | 2037-2045 | VBD | denotes | produced |
T10693 | 2046-2053 | JJ | denotes | similar |
T10694 | 2054-2061 | NNS | denotes | amounts |
T10695 | 2062-2064 | IN | denotes | of |
T10696 | 2065-2070 | NNP | denotes | TGF-β |
T10697 | 2070-2071 | : | denotes | ; |
T10698 | 2072-2074 | IN | denotes | in |
T10699 | 2075-2083 | NN | denotes | addition |
T10700 | 2083-2084 | , | denotes | , |
T10701 | 2085-2090 | NNP | denotes | Smad7 |
T10702 | 2091-2094 | VBD | denotes | was |
T10703 | 2095-2102 | RB | denotes | equally |
T10704 | 2103-2112 | VBN | denotes | expressed |
T10705 | 2113-2114 | NNP | denotes | [ |
T10706 | 2114-2116 | CD | denotes | 23 |
T10707 | 2116-2117 | NNP | denotes | ] |
T10708 | 2118-2120 | IN | denotes | in |
T10709 | 2121-2122 | NNP | denotes | T |
T10710 | 2123-2128 | NNS | denotes | cells |
T10711 | 2129-2131 | IN | denotes | of |
T10712 | 2132-2136 | DT | denotes | both |
T10713 | 2137-2141 | NNS | denotes | mice |
T10714 | 2142-2149 | NNS | denotes | strains |
T10715 | 2150-2151 | -LRB- | denotes | ( |
T10716 | 2151-2157 | NN | denotes | Figure |
T10717 | 2158-2160 | NN | denotes | 7C |
T10718 | 2160-2161 | -RRB- | denotes | ) |
T10719 | 2161-2162 | , | denotes | , |
T10720 | 2163-2173 | VBG | denotes | indicating |
T10721 | 2174-2180 | JJ | denotes | intact |
T10722 | 2181-2186 | JJ | denotes | TGF-β |
T10723 | 2187-2196 | VBG | denotes | signaling |
T10724 | 2196-2197 | . | denotes | . |
T10725 | 3076-3081 | VBN | denotes | Taken |
T10726 | 3082-3090 | RB | denotes | together |
T10727 | 3090-3091 | , | denotes | , |
T10728 | 3092-3097 | DT | denotes | these |
T10729 | 3098-3105 | NNS | denotes | results |
T10730 | 3106-3118 | VBD | denotes | demonstrated |
T10731 | 3119-3120 | DT | denotes | a |
T10732 | 3121-3131 | JJ | denotes | repressive |
T10733 | 3132-3136 | NN | denotes | role |
T10734 | 3137-3139 | IN | denotes | of |
T10735 | 3140-3152 | JJ | denotes | IL-4-induced |
T10736 | 3153-3158 | NNP | denotes | GATA3 |
T10737 | 3159-3172 | NN | denotes | transcription |
T10738 | 3173-3179 | NN | denotes | factor |
T10739 | 3180-3182 | IN | denotes | in |
T10740 | 3183-3186 | DT | denotes | the |
T10741 | 3187-3197 | NN | denotes | generation |
T10742 | 3198-3200 | IN | denotes | of |
T10743 | 3201-3206 | NNP | denotes | iTreg |
T10744 | 3207-3212 | NNS | denotes | cells |
T10745 | 3212-3213 | . | denotes | . |
T26528 | 2208-2213 | CD | denotes | GATA3 |
T26529 | 2214-2218 | NNS | denotes | Acts |
T26530 | 2219-2221 | IN | denotes | as |
T26531 | 2222-2223 | DT | denotes | a |
T26532 | 2224-2232 | JJ | denotes | Negative |
T26533 | 2233-2242 | NNP | denotes | Regulator |
T26534 | 2243-2245 | IN | denotes | of |
T26535 | 2246-2251 | NNP | denotes | FOXP3 |
T26536 | 2252-2262 | NNP | denotes | Expression |
T26537 | 2263-2264 | -LRB- | denotes | ( |
T26538 | 2264-2265 | NNP | denotes | A |
T26539 | 2265-2266 | -RRB- | denotes | ) |
T26540 | 2267-2272 | NNP | denotes | Human |
T26541 | 2273-2278 | JJ | denotes | naive |
T26542 | 2279-2282 | NNP | denotes | CD4 |
T26543 | 2282-2283 | CD | denotes | + |
T26544 | 2283-2287 | NNP | denotes | CDRA |
T26545 | 2287-2288 | CD | denotes | + |
T26546 | 2289-2290 | NNP | denotes | T |
T26547 | 2291-2296 | NNS | denotes | cells |
T26548 | 2297-2301 | VBD | denotes | were |
T26549 | 2302-2312 | VBN | denotes | transduced |
T26550 | 2313-2317 | IN | denotes | with |
T26551 | 2318-2319 | CD | denotes | 0 |
T26552 | 2319-2320 | , | denotes | , |
T26553 | 2321-2323 | CD | denotes | 20 |
T26554 | 2323-2324 | , | denotes | , |
T26555 | 2325-2328 | CD | denotes | 100 |
T26556 | 2328-2329 | , | denotes | , |
T26557 | 2330-2333 | CC | denotes | and |
T26558 | 2334-2337 | CD | denotes | 500 |
T26559 | 2338-2340 | NN | denotes | nM |
T26560 | 2341-2343 | IN | denotes | of |
T26561 | 2344-2353 | CD | denotes | TAT-GATA3 |
T26562 | 2354-2361 | NN | denotes | protein |
T26563 | 2361-2362 | , | denotes | , |
T26564 | 2363-2366 | CC | denotes | and |
T26565 | 2367-2380 | JJ | denotes | intracellular |
T26566 | 2381-2389 | NN | denotes | presence |
T26567 | 2390-2392 | IN | denotes | of |
T26568 | 2393-2398 | NNP | denotes | GATA3 |
T26569 | 2399-2402 | VBD | denotes | was |
T26570 | 2403-2411 | VBN | denotes | analyzed |
T26571 | 2412-2417 | VBG | denotes | using |
T26572 | 2418-2422 | NNP | denotes | FACS |
T26573 | 2423-2432 | VBG | denotes | following |
T26574 | 2433-2441 | JJ | denotes | anti-CD3 |
T26575 | 2441-2442 | NN | denotes | / |
T26576 | 2442-2446 | CD | denotes | CD28 |
T26577 | 2447-2457 | NN | denotes | activation |
T26578 | 2458-2460 | IN | denotes | of |
T26579 | 2461-2464 | DT | denotes | the |
T26580 | 2465-2470 | NNS | denotes | cells |
T26581 | 2470-2471 | . | denotes | . |
T26582 | 2472-2484 | JJ | denotes | GFP-positive |
T26583 | 2485-2490 | NNS | denotes | cells |
T26584 | 2491-2495 | VBD | denotes | were |
T26585 | 2496-2501 | VBN | denotes | gated |
T26586 | 2502-2505 | CC | denotes | and |
T26587 | 2506-2514 | VBN | denotes | analyzed |
T26588 | 2515-2518 | IN | denotes | for |
T26589 | 2519-2532 | JJ | denotes | intracellular |
T26590 | 2533-2538 | CD | denotes | FOXP3 |
T26591 | 2539-2549 | NN | denotes | expression |
T26592 | 2550-2559 | VBG | denotes | following |
T26593 | 2560-2561 | DT | denotes | a |
T26594 | 2562-2565 | JJ | denotes | 2-d |
T26595 | 2566-2576 | NN | denotes | incubation |
T26596 | 2577-2583 | NN | denotes | period |
T26597 | 2584-2585 | -LRB- | denotes | ( |
T26598 | 2585-2590 | JJR | denotes | lower |
T26599 | 2591-2596 | NN | denotes | panel |
T26600 | 2596-2597 | -RRB- | denotes | ) |
T26601 | 2597-2598 | . | denotes | . |
T26602 | 2599-2603 | NNS | denotes | Data |
T26603 | 2604-2607 | VBP | denotes | are |
T26604 | 2608-2622 | NN | denotes | representative |
T26605 | 2623-2625 | IN | denotes | of |
T26606 | 2626-2630 | CD | denotes | four |
T26607 | 2631-2642 | JJ | denotes | independent |
T26608 | 2643-2654 | NNS | denotes | experiments |
T26609 | 2654-2655 | . | denotes | . |
T26610 | 2656-2657 | -LRB- | denotes | ( |
T26611 | 2657-2658 | NNP | denotes | B |
T26612 | 2658-2659 | -RRB- | denotes | ) |
T26613 | 2660-2663 | NNP | denotes | CD4 |
T26614 | 2663-2664 | NNP | denotes | + |
T26615 | 2664-2668 | NNP | denotes | CD25 |
T26616 | 2668-2669 | VBD | denotes | − |
T26617 | 2670-2671 | NNP | denotes | T |
T26618 | 2672-2677 | NNS | denotes | cells |
T26619 | 2678-2682 | VBD | denotes | were |
T26620 | 2683-2691 | VBN | denotes | isolated |
T26621 | 2692-2696 | IN | denotes | from |
T26622 | 2697-2701 | CD | denotes | D011 |
T26623 | 2701-2704 | CD | denotes | .10 |
T26624 | 2705-2708 | CC | denotes | and |
T26625 | 2709-2726 | JJ | denotes | D011.10xCD2-GATA3 |
T26626 | 2727-2731 | NNS | denotes | mice |
T26627 | 2732-2735 | CC | denotes | and |
T26628 | 2736-2743 | VBN | denotes | treated |
T26629 | 2744-2748 | IN | denotes | with |
T26630 | 2749-2752 | NNP | denotes | OVA |
T26631 | 2753-2756 | CC | denotes | and |
T26632 | 2757-2762 | NNP | denotes | TGF-β |
T26633 | 2763-2766 | IN | denotes | for |
T26634 | 2767-2769 | CD | denotes | 96 |
T26635 | 2770-2772 | NN | denotes | h. |
T26636 | 2773-2780 | NNP | denotes | Surface |
T26637 | 2781-2784 | NNP | denotes | CD4 |
T26638 | 2785-2788 | CC | denotes | and |
T26639 | 2789-2802 | JJ | denotes | intracellular |
T26640 | 2803-2808 | CD | denotes | FOXP3 |
T26641 | 2809-2813 | VBD | denotes | were |
T26642 | 2814-2822 | VBN | denotes | measured |
T26643 | 2823-2825 | IN | denotes | by |
T26644 | 2826-2830 | NNP | denotes | FACS |
T26645 | 2830-2831 | . | denotes | . |
T26646 | 2832-2837 | DT | denotes | These |
T26647 | 2838-2842 | NNS | denotes | data |
T26648 | 2843-2846 | VBP | denotes | are |
T26649 | 2847-2861 | NN | denotes | representative |
T26650 | 2862-2864 | IN | denotes | of |
T26651 | 2865-2870 | CD | denotes | three |
T26652 | 2871-2882 | JJ | denotes | independent |
T26653 | 2883-2894 | NNS | denotes | experiments |
T26654 | 2894-2895 | . | denotes | . |
T26655 | 2896-2897 | -LRB- | denotes | ( |
T26656 | 2897-2898 | $ | denotes | C |
T26657 | 2898-2899 | -RRB- | denotes | ) |
T26658 | 2900-2903 | DT | denotes | The |
T26659 | 2904-2909 | NNS | denotes | cells |
T26660 | 2910-2917 | VBN | denotes | treated |
T26661 | 2918-2920 | IN | denotes | as |
T26662 | 2921-2923 | IN | denotes | in |
T26663 | 2924-2925 | -LRB- | denotes | ( |
T26664 | 2925-2926 | NNP | denotes | B |
T26665 | 2926-2927 | -RRB- | denotes | ) |
T26666 | 2928-2932 | VBD | denotes | were |
T26667 | 2933-2942 | VBN | denotes | harvested |
T26668 | 2943-2946 | CC | denotes | and |
T26669 | 2947-2951 | NNP | denotes | mRNA |
T26670 | 2952-2955 | VBD | denotes | was |
T26671 | 2956-2966 | VBN | denotes | quantified |
T26672 | 2967-2969 | IN | denotes | by |
T26673 | 2970-2979 | JJ | denotes | real-time |
T26674 | 2980-2983 | NNP | denotes | PCR |
T26675 | 2984-2987 | IN | denotes | for |
T26676 | 2988-2993 | NNP | denotes | SMAD7 |
T26677 | 2994-2997 | CC | denotes | and |
T26678 | 2998-3003 | NNP | denotes | TGF-β |
T26679 | 3004-3014 | NN | denotes | expression |
T26680 | 3014-3015 | . | denotes | . |
T26681 | 3016-3020 | NNS | denotes | Bars |
T26682 | 3021-3025 | VBP | denotes | show |
T26683 | 3026-3029 | DT | denotes | the |
T26684 | 3030-3034 | JJ | denotes | mean |
T26685 | 3035-3036 | NN | denotes | ± |
T26686 | 3037-3039 | NNP | denotes | SD |
T26687 | 3040-3042 | IN | denotes | of |
T26688 | 3043-3048 | CD | denotes | three |
T26689 | 3049-3060 | JJ | denotes | independent |
T26690 | 3061-3072 | NNS | denotes | experiments |
T26691 | 3072-3073 | . | denotes | . |
R7826 | T10354 | T10356 | det | a,role |
R7827 | T10355 | T10356 | amod | potential,role |
R7828 | T10356 | T10353 | dobj | role,hypothesized |
R7829 | T10357 | T10356 | prep | for,role |
R7830 | T10358 | T10357 | pobj | GATA3,for |
R7831 | T10359 | T10356 | prep | in,role |
R7832 | T10360 | T10359 | pcomp | repressing,in |
R7833 | T10361 | T10360 | dobj | FOXP3,repressing |
R7834 | T10362 | T10353 | punct | .,hypothesized |
R7835 | T10363 | T10366 | advmod | Besides,s |
R7836 | T10364 | T10365 | compound | GATA3,′ |
R7837 | T10365 | T10366 | nsubj | ′,s |
R7838 | T10366 | T10376 | advcl | s,s |
R7839 | T10367 | T10369 | amod | well-known,effect |
R7840 | T10368 | T10369 | amod | positive,effect |
R7841 | T10369 | T10366 | dobj | effect,s |
R7842 | T10370 | T10369 | prep | on,effect |
R7843 | T10371 | T10372 | compound | gene,regulation |
R7844 | T10372 | T10370 | pobj | regulation,on |
R7845 | T10373 | T10372 | punct | ",",regulation |
R7846 | T10374 | T10375 | compound | GATA3,′ |
R7847 | T10375 | T10376 | nsubj | ′,s |
R7848 | T10376 | T10376 | ROOT | s,s |
R7849 | T10377 | T10378 | amod | repressive,capabilities |
R7850 | T10378 | T10381 | nsubjpass | capabilities,shown |
R7851 | T10379 | T10381 | auxpass | were,shown |
R7852 | T10380 | T10381 | advmod | previously,shown |
R7853 | T10381 | T10376 | ccomp | shown,s |
R7854 | T10382 | T10383 | aux | to,restrict |
R7855 | T10383 | T10381 | xcomp | restrict,shown |
R7856 | T10384 | T10385 | amod | Th1,commitment |
R7857 | T10385 | T10383 | dobj | commitment,restrict |
R7858 | T10386 | T10383 | prep | by,restrict |
R7859 | T10387 | T10386 | pcomp | inhibiting,by |
R7860 | T10388 | T10389 | compound | STAT4,expression |
R7861 | T10389 | T10387 | dobj | expression,inhibiting |
R7862 | T10390 | T10392 | compound | [,] |
R7863 | T10391 | T10392 | compound | "2,21",] |
R7874 | T10402 | T10376 | punct | .,s |
R7875 | T10403 | T10404 | aux | To,investigate |
R7876 | T10404 | T10414 | advcl | investigate,transduced |
R7877 | T10405 | T10409 | mark | whether,inhibit |
R7878 | T10406 | T10409 | nsubj | GATA3,inhibit |
R7879 | T10407 | T10409 | aux | can,inhibit |
R7880 | T10408 | T10409 | advmod | directly,inhibit |
R7881 | T10409 | T10404 | ccomp | inhibit,investigate |
R7882 | T10410 | T10411 | nummod | FOXP3,induction |
R7883 | T10411 | T10409 | dobj | induction,inhibit |
R7884 | T10412 | T10414 | punct | ",",transduced |
R7885 | T10413 | T10414 | nsubj | we,transduced |
R7886 | T10414 | T10414 | ROOT | transduced,transduced |
R7887 | T10415 | T10414 | dobj | GATA3,transduced |
R7888 | T10416 | T10415 | cc | or,GATA3 |
R7889 | T10417 | T10419 | det | a,GATA3 |
R7890 | T10418 | T10419 | amod | truncated,GATA3 |
R7891 | T10419 | T10415 | conj | GATA3,GATA3 |
R7892 | T10420 | T10419 | acl | lacking,GATA3 |
R7893 | T10421 | T10423 | det | the,domain |
R7894 | T10422 | T10423 | amod | DNA-binding,domain |
R7895 | T10423 | T10420 | dobj | domain,lacking |
R7896 | T10424 | T10423 | prep | in,domain |
R7897 | T10425 | T10429 | amod | human,CD45RA |
R7898 | T10426 | T10429 | amod | primary,CD45RA |
R7899 | T10427 | T10429 | compound | CD4,CD45RA |
R7900 | T10428 | T10429 | compound | +,CD45RA |
R7901 | T10429 | T10424 | pobj | CD45RA,in |
R7902 | T10430 | T10414 | conj | +,transduced |
R7903 | T10431 | T10432 | compound | T,cells |
R7904 | T10432 | T10430 | dobj | cells,+ |
R7905 | T10433 | T10430 | advcl | using,+ |
R7906 | T10434 | T10439 | det | a,GATA3 |
R7907 | T10435 | T10438 | amod | TAT-fused,expressed |
R7908 | T10436 | T10438 | punct | ",",expressed |
R7909 | T10437 | T10438 | advmod | recombinantly,expressed |
R7910 | T10438 | T10439 | amod | expressed,GATA3 |
R7911 | T10439 | T10433 | dobj | GATA3,using |
R7912 | T10440 | T10430 | punct | .,+ |
R7913 | T10441 | T10447 | prep | After,activated |
R7914 | T10442 | T10441 | pobj | transduction,After |
R7915 | T10443 | T10447 | punct | ",",activated |
R7916 | T10444 | T10445 | det | the,cells |
R7917 | T10445 | T10447 | nsubjpass | cells,activated |
R7918 | T10446 | T10447 | auxpass | were,activated |
R7919 | T10447 | T10447 | ROOT | activated,activated |
R7920 | T10448 | T10447 | prep | with,activated |
R7921 | T10449 | T10451 | amod | soluble,/ |
R7922 | T10450 | T10451 | amod | anti-CD3,/ |
R7923 | T10451 | T10448 | pobj | /,with |
R7924 | T10452 | T10451 | nummod | CD28,/ |
R7925 | T10453 | T10451 | prep | in,/ |
R7926 | T10454 | T10455 | det | the,presence |
R7927 | T10455 | T10453 | pobj | presence,in |
R7928 | T10456 | T10455 | cc | or,presence |
R7929 | T10457 | T10455 | conj | absence,presence |
R7930 | T10458 | T10457 | prep | of,absence |
R7931 | T10459 | T10458 | pobj | TGF-β,of |
R7932 | T10460 | T10447 | punct | .,activated |
R7933 | T10461 | T10464 | nsubjpass | TAT-GATA3,transduced |
R7934 | T10462 | T10464 | auxpass | was,transduced |
R7935 | T10463 | T10464 | advmod | successfully,transduced |
R7936 | T10464 | T10464 | ROOT | transduced,transduced |
R7937 | T10465 | T10464 | prep | in,transduced |
R7938 | T10466 | T10470 | det | a,manner |
R7939 | T10467 | T10470 | amod | homogeneous,manner |
R7940 | T10468 | T10467 | cc | and,homogeneous |
R7941 | T10469 | T10467 | conj | dose-dependent,homogeneous |
R7942 | T10470 | T10465 | pobj | manner,in |
R7943 | T10471 | T10470 | prep | into,manner |
R7944 | T10472 | T10476 | amod | human,cells |
R7945 | T10473 | T10476 | nmod | CD4,cells |
R7946 | T10474 | T10476 | nummod | +,cells |
R7947 | T10475 | T10476 | compound | T,cells |
R7948 | T10476 | T10471 | pobj | cells,into |
R7949 | T10477 | T10479 | punct | (,7A |
R7950 | T10478 | T10479 | compound | Figure,7A |
R7951 | T10479 | T10464 | npadvmod | 7A,transduced |
R7952 | T10480 | T10482 | punct | ",",panel |
R7953 | T10481 | T10482 | amod | upper,panel |
R7954 | T10482 | T10479 | appos | panel,7A |
R7955 | T10483 | T10479 | punct | ),7A |
R7956 | T10484 | T10464 | punct | .,transduced |
R7957 | T10485 | T10488 | nummod | TAT-GATA3,expression |
R7958 | T10486 | T10488 | amod | reduced,expression |
R7959 | T10487 | T10488 | nummod | FOXP3,expression |
R7960 | T10488 | T10488 | ROOT | expression,expression |
R7961 | T10489 | T10488 | prep | in,expression |
R7962 | T10490 | T10492 | det | a,manner |
R7963 | T10491 | T10492 | amod | dose-dependent,manner |
R7964 | T10492 | T10489 | pobj | manner,in |
R7965 | T10493 | T10488 | punct | ",",expression |
R7966 | T10494 | T10505 | mark | whereas,affect |
R7967 | T10495 | T10497 | det | a,domain |
R7968 | T10496 | T10497 | amod | DNA-binding,domain |
R7969 | T10497 | T10505 | nsubj | domain,affect |
R7970 | T10498 | T10499 | amod | truncated,version |
R7971 | T10499 | T10497 | appos | version,domain |
R7972 | T10500 | T10499 | punct | (,version |
R7973 | T10501 | T10499 | appos | TAT-ΔDBD-GATA3,version |
R7974 | T10502 | T10499 | punct | ),version |
R7975 | T10503 | T10505 | aux | did,affect |
R7976 | T10504 | T10505 | neg | not,affect |
R7977 | T10505 | T10488 | advcl | affect,expression |
R7978 | T10506 | T10507 | nummod | FOXP3,expression |
R7979 | T10507 | T10505 | dobj | expression,affect |
R7980 | T10508 | T10505 | prep | as,affect |
R7981 | T10509 | T10508 | prep | compared,as |
R7982 | T10510 | T10509 | prep | with,compared |
R7983 | T10511 | T10510 | pobj | expression,with |
R7984 | T10512 | T10511 | prep | in,expression |
R7985 | T10513 | T10514 | amod | untransduced,cells |
R7986 | T10514 | T10512 | pobj | cells,in |
R7987 | T10515 | T10517 | punct | (,7A |
R7988 | T10516 | T10517 | compound | Figure,7A |
R7989 | T10517 | T10511 | appos | 7A,expression |
R7990 | T10518 | T10505 | punct | ),affect |
R7991 | T10519 | T10488 | punct | .,expression |
R7992 | T10520 | T10524 | prep | In,analyzed |
R7993 | T10521 | T10520 | pobj | addition,In |
R7994 | T10522 | T10524 | punct | ",",analyzed |
R7995 | T10523 | T10524 | nsubj | we,analyzed |
R7996 | T10524 | T10524 | ROOT | analyzed,analyzed |
R7997 | T10525 | T10527 | det | the,effect |
R7998 | T10526 | T10527 | amod | inhibitory,effect |
R7999 | T10527 | T10524 | dobj | effect,analyzed |
R8000 | T10528 | T10527 | prep | of,effect |
R8001 | T10529 | T10528 | pobj | GATA3,of |
R8002 | T10530 | T10527 | prep | on,effect |
R8003 | T10531 | T10530 | pobj | FOXP3,on |
R8004 | T10532 | T10531 | prep | in,FOXP3 |
R8005 | T10533 | T10536 | amod | transgenic,mice |
R8006 | T10534 | T10536 | nmod | DO11,mice |
R8007 | T10535 | T10534 | nummod | .10,DO11 |
R8008 | T10536 | T10532 | pobj | mice,in |
R8009 | T10537 | T10524 | punct | ",",analyzed |
R8010 | T10538 | T10539 | advmod | constitutively,overexpressing |
R8011 | T10539 | T10524 | advcl | overexpressing,analyzed |
R8012 | T10540 | T10539 | dobj | GATA3,overexpressing |
R8013 | T10541 | T10539 | prep | under,overexpressing |
R8014 | T10542 | T10543 | det | the,control |
R8015 | T10543 | T10541 | pobj | control,under |
R8016 | T10544 | T10543 | prep | of,control |
R8017 | T10545 | T10549 | det | the,region |
R8018 | T10546 | T10549 | compound | CD2,region |
R8019 | T10547 | T10548 | compound | locus,control |
R8020 | T10548 | T10549 | compound | control,region |
R8021 | T10549 | T10544 | pobj | region,of |
R8022 | T10550 | T10551 | punct | (,DO11.10xCD2-GATA3 |
R8023 | T10551 | T10549 | appos | DO11.10xCD2-GATA3,region |
R8024 | T10552 | T10551 | punct | ),DO11.10xCD2-GATA3 |
R8025 | T10553 | T10524 | punct | .,analyzed |
R8026 | T10554 | T10556 | det | The,selection |
R8027 | T10555 | T10556 | amod | thymic,selection |
R8028 | T10556 | T10561 | nsubj | selection,is |
R8029 | T10557 | T10556 | prep | into,selection |
R8030 | T10558 | T10560 | det | the,lineage |
R8031 | T10559 | T10560 | compound | CD4,lineage |
R8032 | T10560 | T10557 | pobj | lineage,into |
R8033 | T10561 | T10561 | ROOT | is,is |
R8034 | T10562 | T10563 | advmod | largely,intact |
R8035 | T10563 | T10561 | acomp | intact,is |
R8036 | T10564 | T10563 | prep | in,intact |
R8037 | T10565 | T10564 | pobj | DO11.10xCD2-GATA3,in |
R8038 | T10566 | T10568 | punct | (,Hendriks |
R8039 | T10567 | T10568 | compound | RW,Hendriks |
R8040 | T10568 | T10565 | appos | Hendriks,DO11.10xCD2-GATA3 |
R8041 | T10569 | T10571 | punct | ",",data |
R8042 | T10570 | T10571 | amod | unpublished,data |
R8043 | T10571 | T10568 | appos | data,Hendriks |
R8044 | T10572 | T10568 | punct | ),Hendriks |
R8045 | T10573 | T10561 | punct | .,is |
R8046 | T10574 | T10575 | det | These,mice |
R8047 | T10575 | T10576 | nsubj | mice,develop |
R8048 | T10576 | T10576 | ROOT | develop,develop |
R8049 | T10577 | T10576 | dobj | lymphomas,develop |
R8050 | T10578 | T10576 | prep | at,develop |
R8051 | T10579 | T10581 | det | an,age |
R8052 | T10580 | T10581 | amod | older,age |
R8053 | T10581 | T10578 | pobj | age,at |
R8054 | T10582 | T10576 | punct | ",",develop |
R8055 | T10583 | T10576 | cc | but,develop |
R8056 | T10584 | T10590 | nsubjpass | signs,described |
R8057 | T10585 | T10584 | prep | of,signs |
R8058 | T10586 | T10587 | amod | autoimmune,disease |
R8059 | T10587 | T10585 | pobj | disease,of |
R8060 | T10588 | T10590 | auxpass | were,described |
R8061 | T10589 | T10590 | neg | not,described |
R8062 | T10590 | T10576 | conj | described,develop |
R8063 | T10591 | T10593 | nmod | [,] |
R8064 | T10592 | T10593 | nummod | 22,] |
R8065 | T10593 | T10590 | dobj | ],described |
R8066 | T10594 | T10576 | punct | .,develop |
R8067 | T10595 | T10596 | aux | To,investigate |
R8068 | T10596 | T10610 | advcl | investigate,were |
R8069 | T10597 | T10598 | det | the,effect |
R8070 | T10598 | T10596 | dobj | effect,investigate |
R8071 | T10599 | T10598 | prep | of,effect |
R8072 | T10600 | T10599 | pobj | GATA3,of |
R8073 | T10601 | T10598 | prep | on,effect |
R8074 | T10602 | T10601 | pobj | iTreg,on |
R8075 | T10603 | T10602 | punct | ",",iTreg |
R8076 | T10604 | T10608 | compound | CD4,CD25 |
R8077 | T10605 | T10608 | compound | +,CD25 |
R8078 | T10606 | T10608 | compound | CD62L,CD25 |
R8079 | T10607 | T10608 | compound | +,CD25 |
R8080 | T10608 | T10602 | conj | CD25,iTreg |
R8081 | T10609 | T10610 | nsubj | cells,were |
R8082 | T10610 | T10610 | ROOT | were,were |
R8083 | T10611 | T10610 | acomp | isolated,were |
R8084 | T10612 | T10611 | punct | ",",isolated |
R8085 | T10613 | T10611 | conj | activated,isolated |
R8086 | T10614 | T10613 | prep | with,activated |
R8087 | T10615 | T10614 | pobj | OVA,with |
R8088 | T10616 | T10613 | prep | in,activated |
R8089 | T10617 | T10618 | det | the,presence |
R8090 | T10618 | T10616 | pobj | presence,in |
R8091 | T10619 | T10618 | cc | or,presence |
R8092 | T10620 | T10618 | conj | absence,presence |
R8093 | T10621 | T10620 | prep | of,absence |
R8094 | T10622 | T10621 | pobj | TGF-β,of |
R8095 | T10623 | T10620 | punct | ",",absence |
R8096 | T10624 | T10620 | cc | and,absence |
R8097 | T10625 | T10626 | amod | Foxp3,expression |
R8098 | T10626 | T10620 | conj | expression,absence |
R8099 | T10627 | T10628 | auxpass | was,analyzed |
R8100 | T10628 | T10610 | conj | analyzed,were |
R8101 | T10629 | T10628 | prep | after,analyzed |
R8102 | T10630 | T10631 | nummod | 4,d |
R8103 | T10631 | T10629 | pobj | d,after |
R8104 | T10632 | T10610 | punct | .,were |
R8105 | T10633 | T10637 | det | The,CD25 |
R8106 | T10634 | T10637 | amod | naive,CD25 |
R8107 | T10635 | T10637 | compound | CD4,CD25 |
R8108 | T10636 | T10637 | compound | +,CD25 |
R8109 | T10637 | T10637 | ROOT | CD25,CD25 |
R8110 | T10638 | T10639 | nsubj | cells,were |
R8111 | T10639 | T10639 | ROOT | were,were |
R8112 | T10640 | T10639 | acomp | Foxp3,were |
R8113 | T10641 | T10643 | punct | (,data |
R8114 | T10642 | T10643 | amod | unpublished,data |
R8115 | T10643 | T10640 | appos | data,Foxp3 |
R8116 | T10644 | T10640 | punct | ),Foxp3 |
R8117 | T10645 | T10639 | punct | .,were |
R8118 | T10646 | T10647 | mark | As,described |
R8119 | T10647 | T10656 | advcl | described,Foxp3 |
R8120 | T10648 | T10647 | prep | for,described |
R8121 | T10649 | T10651 | det | the,cells |
R8122 | T10650 | T10651 | amod | human,cells |
R8123 | T10651 | T10648 | pobj | cells,for |
R8124 | T10652 | T10656 | punct | ",",Foxp3 |
R8125 | T10653 | T10656 | nmod | TGF-β,Foxp3 |
R8126 | T10654 | T10655 | advmod | dramatically,up-regulated |
R8127 | T10655 | T10656 | amod | up-regulated,Foxp3 |
R8128 | T10656 | T10656 | ROOT | Foxp3,Foxp3 |
R8129 | T10657 | T10656 | prep | in,Foxp3 |
R8130 | T10658 | T10663 | det | the,mice |
R8131 | T10659 | T10663 | compound | DO11,mice |
R8132 | T10660 | T10661 | nummod | .10,littermate |
R8133 | T10661 | T10662 | compound | littermate,control |
R8134 | T10662 | T10663 | compound | control,mice |
R8135 | T10663 | T10657 | pobj | mice,in |
R8136 | T10664 | T10656 | punct | .,Foxp3 |
R8137 | T10665 | T10674 | prep | In,showed |
R8138 | T10666 | T10665 | pobj | contrast,In |
R8139 | T10667 | T10674 | punct | ",",showed |
R8140 | T10668 | T10674 | nsubj | cells,showed |
R8141 | T10669 | T10668 | prep | from,cells |
R8142 | T10670 | T10673 | det | the,mice |
R8143 | T10671 | T10673 | nmod | CD2-GATA3xDO11,mice |
R8144 | T10672 | T10671 | nummod | .10,CD2-GATA3xDO11 |
R8145 | T10673 | T10669 | pobj | mice,from |
R8146 | T10674 | T10674 | ROOT | showed,showed |
R8147 | T10675 | T10676 | advmod | dramatically,reduced |
R8148 | T10676 | T10678 | amod | reduced,expression |
R8149 | T10677 | T10678 | amod | Foxp3,expression |
R8150 | T10678 | T10674 | dobj | expression,showed |
R8151 | T10679 | T10680 | advmod | when,activated |
R8152 | T10680 | T10674 | advcl | activated,showed |
R8153 | T10681 | T10680 | prep | with,activated |
R8154 | T10682 | T10681 | pobj | TGF-β,with |
R8155 | T10683 | T10682 | cc | and,TGF-β |
R8156 | T10684 | T10682 | conj | OVA,TGF-β |
R8157 | T10685 | T10687 | punct | (,7B |
R8158 | T10686 | T10687 | compound | Figure,7B |
R8159 | T10687 | T10684 | appos | 7B,OVA |
R8160 | T10688 | T10687 | punct | ),7B |
R8161 | T10689 | T10674 | punct | .,showed |
R8162 | T10690 | T10691 | det | All,mice |
R8163 | T10691 | T10692 | nsubj | mice,produced |
R8164 | T10692 | T10704 | ccomp | produced,expressed |
R8165 | T10693 | T10694 | amod | similar,amounts |
R8166 | T10694 | T10692 | dobj | amounts,produced |
R8167 | T10695 | T10694 | prep | of,amounts |
R8168 | T10696 | T10695 | pobj | TGF-β,of |
R8169 | T10697 | T10704 | punct | ;,expressed |
R8170 | T10698 | T10704 | prep | in,expressed |
R8171 | T10699 | T10698 | pobj | addition,in |
R8172 | T10700 | T10704 | punct | ",",expressed |
R8173 | T10701 | T10704 | nsubjpass | Smad7,expressed |
R8174 | T10702 | T10704 | auxpass | was,expressed |
R8175 | T10703 | T10704 | advmod | equally,expressed |
R8176 | T10704 | T10704 | ROOT | expressed,expressed |
R8177 | T10705 | T10707 | nmod | [,] |
R8178 | T10706 | T10707 | nummod | 23,] |
R8179 | T10707 | T10704 | dobj | ],expressed |
R8180 | T10708 | T10707 | prep | in,] |
R8181 | T10709 | T10710 | compound | T,cells |
R8182 | T10710 | T10708 | pobj | cells,in |
R8183 | T10711 | T10710 | prep | of,cells |
R8184 | T10712 | T10713 | preconj | both,mice |
R8185 | T10713 | T10711 | pobj | mice,of |
R8186 | T10714 | T10713 | conj | strains,mice |
R8187 | T10715 | T10717 | punct | (,7C |
R8188 | T10716 | T10717 | compound | Figure,7C |
R8189 | T10717 | T10714 | appos | 7C,strains |
R8190 | T10718 | T10717 | punct | ),7C |
R8191 | T10719 | T10704 | punct | ",",expressed |
R8192 | T10720 | T10704 | advcl | indicating,expressed |
R8193 | T10721 | T10723 | amod | intact,signaling |
R8194 | T10722 | T10723 | amod | TGF-β,signaling |
R8195 | T10723 | T10720 | dobj | signaling,indicating |
R8196 | T10724 | T10704 | punct | .,expressed |
R8197 | T10725 | T10730 | advcl | Taken,demonstrated |
R8198 | T10726 | T10725 | advmod | together,Taken |
R8199 | T10727 | T10730 | punct | ",",demonstrated |
R8200 | T10728 | T10729 | det | these,results |
R8201 | T10729 | T10730 | nsubj | results,demonstrated |
R8202 | T10730 | T10730 | ROOT | demonstrated,demonstrated |
R8203 | T10731 | T10733 | det | a,role |
R8204 | T10732 | T10733 | amod | repressive,role |
R8205 | T10733 | T10730 | dobj | role,demonstrated |
R8206 | T10734 | T10733 | prep | of,role |
R8207 | T10735 | T10738 | amod | IL-4-induced,factor |
R8208 | T10736 | T10738 | compound | GATA3,factor |
R8209 | T10737 | T10738 | compound | transcription,factor |
R8210 | T10738 | T10734 | pobj | factor,of |
R8211 | T10739 | T10730 | prep | in,demonstrated |
R8212 | T10740 | T10741 | det | the,generation |
R8213 | T10741 | T10739 | pobj | generation,in |
R8214 | T10742 | T10741 | prep | of,generation |
R8215 | T10743 | T10744 | compound | iTreg,cells |
R8216 | T10744 | T10742 | pobj | cells,of |
R8217 | T10745 | T10730 | punct | .,demonstrated |
R19603 | T26528 | T26529 | nummod | GATA3,Acts |
R19604 | T26529 | T26549 | nsubjpass | Acts,transduced |
R19605 | T26530 | T26529 | prep | as,Acts |
R19606 | T26531 | T26533 | det | a,Regulator |
R19607 | T26532 | T26533 | amod | Negative,Regulator |
R19608 | T26533 | T26530 | pobj | Regulator,as |
R19609 | T26534 | T26533 | prep | of,Regulator |
R19610 | T26535 | T26536 | compound | FOXP3,Expression |
R19611 | T26536 | T26534 | pobj | Expression,of |
R19612 | T26537 | T26536 | punct | (,Expression |
R19613 | T26538 | T26536 | appos | A,Expression |
R19614 | T26539 | T26536 | punct | ),Expression |
R19615 | T26540 | T26547 | amod | Human,cells |
R19616 | T26541 | T26547 | amod | naive,cells |
R19617 | T26542 | T26547 | nmod | CD4,cells |
R19618 | T26543 | T26547 | nummod | +,cells |
R19619 | T26544 | T26547 | nmod | CDRA,cells |
R19620 | T26545 | T26547 | nummod | +,cells |
R19621 | T26546 | T26547 | compound | T,cells |
R19622 | T26547 | T26549 | nsubjpass | cells,transduced |
R19623 | T26548 | T26549 | auxpass | were,transduced |
R19624 | T26549 | T26549 | ROOT | transduced,transduced |
R19625 | T26550 | T26549 | prep | with,transduced |
R19626 | T26551 | T26550 | pobj | 0,with |
R19627 | T26552 | T26551 | punct | ",",0 |
R19628 | T26553 | T26551 | conj | 20,0 |
R19629 | T26554 | T26551 | punct | ",",0 |
R19630 | T26555 | T26551 | conj | 100,0 |
R19631 | T26556 | T26549 | punct | ",",transduced |
R19632 | T26557 | T26549 | cc | and,transduced |
R19633 | T26558 | T26559 | nummod | 500,nM |
R19634 | T26559 | T26570 | nsubjpass | nM,analyzed |
R19635 | T26560 | T26559 | prep | of,nM |
R19636 | T26561 | T26562 | nummod | TAT-GATA3,protein |
R19637 | T26562 | T26560 | pobj | protein,of |
R19638 | T26563 | T26559 | punct | ",",nM |
R19639 | T26564 | T26559 | cc | and,nM |
R19640 | T26565 | T26566 | amod | intracellular,presence |
R19641 | T26566 | T26559 | conj | presence,nM |
R19642 | T26567 | T26559 | prep | of,nM |
R19643 | T26568 | T26567 | pobj | GATA3,of |
R19644 | T26569 | T26570 | auxpass | was,analyzed |
R19645 | T26570 | T26549 | conj | analyzed,transduced |
R19646 | T26571 | T26570 | advcl | using,analyzed |
R19647 | T26572 | T26571 | dobj | FACS,using |
R19648 | T26573 | T26571 | prep | following,using |
R19649 | T26574 | T26577 | amod | anti-CD3,activation |
R19650 | T26575 | T26577 | nmod | /,activation |
R19651 | T26576 | T26577 | nummod | CD28,activation |
R19652 | T26577 | T26573 | dobj | activation,following |
R19653 | T26578 | T26577 | prep | of,activation |
R19654 | T26579 | T26580 | det | the,cells |
R19655 | T26580 | T26578 | pobj | cells,of |
R19656 | T26581 | T26570 | punct | .,analyzed |
R19657 | T26582 | T26583 | amod | GFP-positive,cells |
R19658 | T26583 | T26584 | nsubj | cells,were |
R19659 | T26584 | T26584 | ROOT | were,were |
R19660 | T26585 | T26584 | acomp | gated,were |
R19661 | T26586 | T26585 | cc | and,gated |
R19662 | T26587 | T26585 | conj | analyzed,gated |
R19663 | T26588 | T26587 | prep | for,analyzed |
R19664 | T26589 | T26591 | amod | intracellular,expression |
R19665 | T26590 | T26591 | nummod | FOXP3,expression |
R19666 | T26591 | T26588 | pobj | expression,for |
R19667 | T26592 | T26591 | acl | following,expression |
R19668 | T26593 | T26596 | det | a,period |
R19669 | T26594 | T26596 | amod | 2-d,period |
R19670 | T26595 | T26596 | amod | incubation,period |
R19671 | T26596 | T26592 | dobj | period,following |
R19672 | T26597 | T26596 | punct | (,period |
R19673 | T26598 | T26599 | amod | lower,panel |
R19674 | T26599 | T26596 | appos | panel,period |
R19675 | T26600 | T26596 | punct | ),period |
R19676 | T26601 | T26584 | punct | .,were |
R19677 | T26602 | T26603 | nsubj | Data,are |
R19678 | T26603 | T26603 | ROOT | are,are |
R19679 | T26604 | T26603 | attr | representative,are |
R19680 | T26605 | T26604 | prep | of,representative |
R19681 | T26606 | T26608 | nummod | four,experiments |
R19682 | T26607 | T26608 | amod | independent,experiments |
R19683 | T26608 | T26605 | pobj | experiments,of |
R19684 | T26609 | T26603 | punct | .,are |
R19685 | T26610 | T26616 | punct | (,− |
R19686 | T26611 | T26616 | dep | B,− |
R19687 | T26612 | T26611 | punct | ),B |
R19688 | T26613 | T26615 | compound | CD4,CD25 |
R19689 | T26614 | T26615 | compound | +,CD25 |
R19690 | T26615 | T26616 | nsubj | CD25,− |
R19691 | T26616 | T26618 | amod | −,cells |
R19692 | T26617 | T26618 | compound | T,cells |
R19693 | T26618 | T26620 | nsubjpass | cells,isolated |
R19694 | T26619 | T26620 | auxpass | were,isolated |
R19695 | T26620 | T26620 | ROOT | isolated,isolated |
R19696 | T26621 | T26620 | prep | from,isolated |
R19697 | T26622 | T26623 | nummod | D011,.10 |
R19698 | T26623 | T26626 | nummod | .10,mice |
R19699 | T26624 | T26623 | cc | and,.10 |
R19700 | T26625 | T26626 | amod | D011.10xCD2-GATA3,mice |
R19701 | T26626 | T26621 | pobj | mice,from |
R19702 | T26627 | T26620 | cc | and,isolated |
R19703 | T26628 | T26620 | conj | treated,isolated |
R19704 | T26629 | T26628 | prep | with,treated |
R19705 | T26630 | T26629 | pobj | OVA,with |
R19706 | T26631 | T26630 | cc | and,OVA |
R19707 | T26632 | T26630 | conj | TGF-β,OVA |
R19708 | T26633 | T26628 | prep | for,treated |
R19709 | T26634 | T26637 | nummod | 96,CD4 |
R19710 | T26635 | T26637 | compound | h.,CD4 |
R19711 | T26636 | T26637 | compound | Surface,CD4 |
R19712 | T26637 | T26633 | pobj | CD4,for |
R19713 | T26638 | T26637 | cc | and,CD4 |
R19714 | T26639 | T26640 | amod | intracellular,FOXP3 |
R19715 | T26640 | T26637 | conj | FOXP3,CD4 |
R19716 | T26641 | T26642 | auxpass | were,measured |
R19717 | T26642 | T26620 | conj | measured,isolated |
R19718 | T26643 | T26642 | agent | by,measured |
R19719 | T26644 | T26643 | pobj | FACS,by |
R19720 | T26645 | T26620 | punct | .,isolated |
R19721 | T26646 | T26647 | det | These,data |
R19722 | T26647 | T26648 | nsubj | data,are |
R19723 | T26648 | T26648 | ROOT | are,are |
R19724 | T26649 | T26648 | attr | representative,are |
R19725 | T26650 | T26649 | prep | of,representative |
R19726 | T26651 | T26653 | nummod | three,experiments |
R19727 | T26652 | T26653 | amod | independent,experiments |
R19728 | T26653 | T26650 | pobj | experiments,of |
R19729 | T26654 | T26648 | punct | .,are |
R19730 | T26655 | T26656 | punct | (,C |
R19731 | T26656 | T26667 | meta | C,harvested |
R19732 | T26657 | T26656 | punct | ),C |
R19733 | T26658 | T26659 | det | The,cells |
R19734 | T26659 | T26667 | nsubjpass | cells,harvested |
R19735 | T26660 | T26659 | acl | treated,cells |
R19736 | T26661 | T26660 | prep | as,treated |
R19737 | T26662 | T26661 | prep | in,as |
R19738 | T26663 | T26664 | punct | (,B |
R19739 | T26664 | T26662 | pobj | B,in |
R19740 | T26665 | T26659 | punct | ),cells |
R19741 | T26666 | T26667 | auxpass | were,harvested |
R19742 | T26667 | T26667 | ROOT | harvested,harvested |
R19743 | T26668 | T26667 | cc | and,harvested |
R19744 | T26669 | T26671 | nsubjpass | mRNA,quantified |
R19745 | T26670 | T26671 | auxpass | was,quantified |
R19746 | T26671 | T26667 | conj | quantified,harvested |
R19747 | T26672 | T26671 | agent | by,quantified |
R19748 | T26673 | T26674 | amod | real-time,PCR |
R19749 | T26674 | T26672 | pobj | PCR,by |
R19750 | T26675 | T26671 | prep | for,quantified |
R19751 | T26676 | T26675 | pobj | SMAD7,for |
R19752 | T26677 | T26676 | cc | and,SMAD7 |
R19753 | T26678 | T26679 | compound | TGF-β,expression |
R19754 | T26679 | T26676 | conj | expression,SMAD7 |
R19755 | T26680 | T26671 | punct | .,quantified |
R19756 | T26681 | T26682 | nsubj | Bars,show |
R19757 | T26682 | T26682 | ROOT | show,show |
R19758 | T26683 | T26686 | det | the,SD |
R19759 | T26684 | T26686 | amod | mean,SD |
R19760 | T26685 | T26686 | compound | ±,SD |
R19761 | T26686 | T26682 | dobj | SD,show |
R19762 | T26687 | T26686 | prep | of,SD |
R19763 | T26688 | T26690 | nummod | three,experiments |
R19764 | T26689 | T26690 | amod | independent,experiments |
R19765 | T26690 | T26687 | pobj | experiments,of |
R19766 | T26691 | T26682 | punct | .,show |
R7805 | T10333 | T10334 | nsubj | GATA3,Is |
R7806 | T10334 | T10353 | ccomp | Is,hypothesized |
R7807 | T10335 | T10337 | det | a,Regulator |
R7808 | T10336 | T10337 | amod | Negative,Regulator |
R7809 | T10337 | T10334 | attr | Regulator,Is |
R7810 | T10338 | T10337 | prep | of,Regulator |
R7811 | T10339 | T10341 | compound | FOXP3,FOXP3 |
R7812 | T10340 | T10341 | compound | Expression,FOXP3 |
R7813 | T10341 | T10342 | compound | FOXP3,expression |
R7814 | T10342 | T10338 | pobj | expression,of |
R7815 | T10343 | T10346 | amod | decreased,expression |
R7816 | T10344 | T10343 | advmod | once,decreased |
R7817 | T10345 | T10346 | amod | GATA3,expression |
R7818 | T10346 | T10347 | nsubj | expression,is |
R7819 | T10347 | T10334 | conj | is,Is |
R7820 | T10348 | T10347 | acomp | high,is |
R7821 | T10349 | T10353 | punct | ;,hypothesized |
R7822 | T10350 | T10353 | advmod | therefore,hypothesized |
R7823 | T10351 | T10353 | punct | ",",hypothesized |
R7824 | T10352 | T10353 | nsubj | we,hypothesized |
R7825 | T10353 | T10353 | ROOT | hypothesized,hypothesized |
R7864 | T10392 | T10389 | appos | ],expression |
R7865 | T10393 | T10392 | punct | ",",] |
R7866 | T10394 | T10392 | cc | and,] |
R7867 | T10395 | T10396 | advmod | therefore,GATA3 |
R7868 | T10396 | T10397 | nsubj | GATA3,prevents |
R7869 | T10397 | T10389 | relcl | prevents,expression |
R7870 | T10398 | T10397 | dobj | differentiation,prevents |
R7871 | T10399 | T10397 | prep | into,prevents |
R7872 | T10400 | T10401 | amod | Th1,cells |
R7873 | T10401 | T10399 | pobj | cells,into |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9855 | 234-244 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
T9856 | 659-671 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
T9857 | 1470-1473 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | age |
T9858 | 1986-2006 | http://purl.obolibrary.org/obo/GO_0036365 | denotes | activated with TGF-β |
T9859 | 1986-2006 | http://purl.obolibrary.org/obo/GO_0036366 | denotes | activated with TGF-β |
T9860 | 1986-2006 | http://purl.obolibrary.org/obo/GO_1901389 | denotes | activated with TGF-β |
T9861 | 1986-2006 | http://purl.obolibrary.org/obo/GO_1901390 | denotes | activated with TGF-β |
T9862 | 1986-2006 | http://purl.obolibrary.org/obo/GO_0036363 | denotes | activated with TGF-β |
T9863 | 1986-2006 | http://purl.obolibrary.org/obo/GO_0036364 | denotes | activated with TGF-β |
T9864 | 2187-2196 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T9865 | 3159-3172 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T26346 | 2447-2470 | http://purl.obolibrary.org/obo/GO_0001775 | denotes | activation of the cells |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10832 | 547-558 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA-binding |
T10833 | 966-977 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA-binding |
T10834 | 547-565 | http://purl.obolibrary.org/obo/GO_0050692 | denotes | DNA-binding domain |
T10835 | 966-984 | http://purl.obolibrary.org/obo/GO_0050692 | denotes | DNA-binding domain |
T10836 | 551-558 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T10837 | 970-977 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T10838 | 3140-3144 | http://purl.obolibrary.org/obo/GO_0005136 | denotes | IL-4 |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10839 | 420-425 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10840 | 597-602 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10841 | 677-682 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10842 | 861-866 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10843 | 1096-1101 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10844 | 1593-1598 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10845 | 1735-1740 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10846 | 1800-1805 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10847 | 1898-1903 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10848 | 2123-2128 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10849 | 3207-3212 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T26715 | 2291-2296 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T26716 | 2465-2470 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T26717 | 2485-2490 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T26718 | 2672-2677 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T26719 | 2904-2909 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T26720 | 2367-2380 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
T26721 | 2519-2532 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
T26722 | 2789-2802 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9839 | 0-49 | Sentence | denotes | GATA3 Is a Negative Regulator of FOXP3 Expression |
T9840 | 50-182 | Sentence | denotes | FOXP3 expression decreased once GATA3 expression is high; therefore, we hypothesized a potential role for GATA3 in repressing FOXP3. |
T9841 | 183-426 | Sentence | denotes | Besides GATA3′s well-known positive effect on gene regulation, GATA3′s repressive capabilities were previously shown to restrict Th1 commitment by inhibiting STAT4 expression [2,21], and therefore GATA3 prevents differentiation into Th1 cells. |
T9842 | 427-652 | Sentence | denotes | To investigate whether GATA3 can directly inhibit FOXP3 induction, we transduced GATA3 or a truncated GATA3 lacking the DNA-binding domain in human primary CD4+CD45RA+ T cells using a TAT-fused, recombinantly expressed GATA3. |
T9843 | 653-761 | Sentence | denotes | After transduction, the cells were activated with soluble anti-CD3/CD28 in the presence or absence of TGF-β. |
T9844 | 762-892 | Sentence | denotes | TAT-GATA3 was successfully transduced in a homogeneous and dose-dependent manner into human CD4+ T cells (Figure 7A, upper panel). |
T9845 | 893-1114 | Sentence | denotes | TAT-GATA3 reduced FOXP3 expression in a dose-dependent manner, whereas a DNA-binding domain truncated version (TAT-ΔDBD-GATA3) did not affect FOXP3 expression as compared with expression in untransduced cells (Figure 7A). |
T9846 | 1115-1314 | Sentence | denotes | In addition, we analyzed the inhibitory effect of GATA3 on FOXP3 in transgenic DO11.10 mice, constitutively overexpressing GATA3 under the control of the CD2 locus control region (DO11.10xCD2-GATA3). |
T9847 | 1315-1428 | Sentence | denotes | The thymic selection into the CD4 lineage is largely intact in DO11.10xCD2-GATA3 (RW Hendriks, unpublished data). |
T9848 | 1429-1531 | Sentence | denotes | These mice develop lymphomas at an older age, but signs of autoimmune disease were not described [22]. |
T9849 | 1532-1714 | Sentence | denotes | To investigate the effect of GATA3 on iTreg, CD4+CD62L+CD25– cells were isolated, activated with OVA in the presence or absence of TGF-β, and Foxp3 expression was analyzed after 4 d. |
T9850 | 1715-1772 | Sentence | denotes | The naive CD4+CD25– cells were Foxp3– (unpublished data). |
T9851 | 1773-1884 | Sentence | denotes | As described for the human cells, TGF-β dramatically up-regulated Foxp3 in the DO11.10 littermate control mice. |
T9852 | 1885-2027 | Sentence | denotes | In contrast, cells from the CD2-GATA3xDO11.10 mice showed dramatically reduced Foxp3 expression when activated with TGF-β and OVA (Figure 7B). |
T9853 | 2028-2197 | Sentence | denotes | All mice produced similar amounts of TGF-β; in addition, Smad7 was equally expressed [23] in T cells of both mice strains (Figure 7C), indicating intact TGF-β signaling. |
T9854 | 3076-3213 | Sentence | denotes | Taken together, these results demonstrated a repressive role of IL-4-induced GATA3 transcription factor in the generation of iTreg cells. |
T26337 | 2208-2262 | Sentence | denotes | GATA3 Acts as a Negative Regulator of FOXP3 Expression |
T26338 | 2263-2471 | Sentence | denotes | (A) Human naive CD4+CDRA+ T cells were transduced with 0, 20, 100, and 500 nM of TAT-GATA3 protein, and intracellular presence of GATA3 was analyzed using FACS following anti-CD3/CD28 activation of the cells. |
T26339 | 2472-2598 | Sentence | denotes | GFP-positive cells were gated and analyzed for intracellular FOXP3 expression following a 2-d incubation period (lower panel). |
T26340 | 2599-2655 | Sentence | denotes | Data are representative of four independent experiments. |
T26341 | 2656-2772 | Sentence | denotes | (B) CD4+CD25− T cells were isolated from D011.10 and D011.10xCD2-GATA3 mice and treated with OVA and TGF-β for 96 h. |
T26342 | 2773-2831 | Sentence | denotes | Surface CD4 and intracellular FOXP3 were measured by FACS. |
T26343 | 2832-2895 | Sentence | denotes | These data are representative of three independent experiments. |
T26344 | 2896-3015 | Sentence | denotes | (C) The cells treated as in (B) were harvested and mRNA was quantified by real-time PCR for SMAD7 and TGF-β expression. |
T26345 | 3016-3073 | Sentence | denotes | Bars show the mean ± SD of three independent experiments. |
T151 | 0-49 | Sentence | denotes | GATA3 Is a Negative Regulator of FOXP3 Expression |
T152 | 50-182 | Sentence | denotes | FOXP3 expression decreased once GATA3 expression is high; therefore, we hypothesized a potential role for GATA3 in repressing FOXP3. |
T153 | 183-426 | Sentence | denotes | Besides GATA3′s well-known positive effect on gene regulation, GATA3′s repressive capabilities were previously shown to restrict Th1 commitment by inhibiting STAT4 expression [2,21], and therefore GATA3 prevents differentiation into Th1 cells. |
T154 | 427-652 | Sentence | denotes | To investigate whether GATA3 can directly inhibit FOXP3 induction, we transduced GATA3 or a truncated GATA3 lacking the DNA-binding domain in human primary CD4+CD45RA+ T cells using a TAT-fused, recombinantly expressed GATA3. |
T155 | 653-761 | Sentence | denotes | After transduction, the cells were activated with soluble anti-CD3/CD28 in the presence or absence of TGF-β. |
T156 | 762-892 | Sentence | denotes | TAT-GATA3 was successfully transduced in a homogeneous and dose-dependent manner into human CD4+ T cells (Figure 7A, upper panel). |
T157 | 893-1114 | Sentence | denotes | TAT-GATA3 reduced FOXP3 expression in a dose-dependent manner, whereas a DNA-binding domain truncated version (TAT-ΔDBD-GATA3) did not affect FOXP3 expression as compared with expression in untransduced cells (Figure 7A). |
T158 | 1115-1314 | Sentence | denotes | In addition, we analyzed the inhibitory effect of GATA3 on FOXP3 in transgenic DO11.10 mice, constitutively overexpressing GATA3 under the control of the CD2 locus control region (DO11.10xCD2-GATA3). |
T159 | 1315-1428 | Sentence | denotes | The thymic selection into the CD4 lineage is largely intact in DO11.10xCD2-GATA3 (RW Hendriks, unpublished data). |
T160 | 1429-1531 | Sentence | denotes | These mice develop lymphomas at an older age, but signs of autoimmune disease were not described [22]. |
T161 | 1532-1714 | Sentence | denotes | To investigate the effect of GATA3 on iTreg, CD4+CD62L+CD25– cells were isolated, activated with OVA in the presence or absence of TGF-β, and Foxp3 expression was analyzed after 4 d. |
T162 | 1715-1772 | Sentence | denotes | The naive CD4+CD25– cells were Foxp3– (unpublished data). |
T163 | 1773-1884 | Sentence | denotes | As described for the human cells, TGF-β dramatically up-regulated Foxp3 in the DO11.10 littermate control mice. |
T164 | 1885-2027 | Sentence | denotes | In contrast, cells from the CD2-GATA3xDO11.10 mice showed dramatically reduced Foxp3 expression when activated with TGF-β and OVA (Figure 7B). |
T165 | 2028-2197 | Sentence | denotes | All mice produced similar amounts of TGF-β; in addition, Smad7 was equally expressed [23] in T cells of both mice strains (Figure 7C), indicating intact TGF-β signaling. |
T166 | 2198-2262 | Sentence | denotes | Figure 7 GATA3 Acts as a Negative Regulator of FOXP3 Expression |
T167 | 2263-2471 | Sentence | denotes | (A) Human naive CD4+CDRA+ T cells were transduced with 0, 20, 100, and 500 nM of TAT-GATA3 protein, and intracellular presence of GATA3 was analyzed using FACS following anti-CD3/CD28 activation of the cells. |
T168 | 2472-2598 | Sentence | denotes | GFP-positive cells were gated and analyzed for intracellular FOXP3 expression following a 2-d incubation period (lower panel). |
T169 | 2599-2655 | Sentence | denotes | Data are representative of four independent experiments. |
T170 | 2656-2772 | Sentence | denotes | (B) CD4+CD25− T cells were isolated from D011.10 and D011.10xCD2-GATA3 mice and treated with OVA and TGF-β for 96 h. |
T171 | 2773-2831 | Sentence | denotes | Surface CD4 and intracellular FOXP3 were measured by FACS. |
T172 | 2832-2895 | Sentence | denotes | These data are representative of three independent experiments. |
T173 | 2896-3015 | Sentence | denotes | (C) The cells treated as in (B) were harvested and mRNA was quantified by real-time PCR for SMAD7 and TGF-β expression. |
T174 | 3016-3073 | Sentence | denotes | Bars show the mean ± SD of three independent experiments. |
T175 | 3076-3213 | Sentence | denotes | Taken together, these results demonstrated a repressive role of IL-4-induced GATA3 transcription factor in the generation of iTreg cells. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T11187 | 0-5 | Protein | denotes | GATA3 | ||
T11188 | 11-29 | Negative_regulation | denotes | Negative Regulator | ||
T11189 | 33-38 | Protein | denotes | FOXP3 | ||
T11190 | 39-49 | Gene_expression | denotes | Expression | ||
T11191 | 50-55 | Protein | denotes | FOXP3 | ||
T11192 | 56-66 | Gene_expression | denotes | expression | ||
T11193 | 67-76 | Negative_regulation | denotes | decreased | ||
T11194 | 82-87 | Protein | denotes | GATA3 | ||
T11195 | 88-98 | Gene_expression | denotes | expression | ||
T11196 | 102-106 | Positive_regulation | denotes | high | ||
T11197 | 147-151 | Regulation | denotes | role | true | |
T11198 | 156-161 | Protein | denotes | GATA3 | ||
T11199 | 165-175 | Negative_regulation | denotes | repressing | ||
T11200 | 176-181 | Protein | denotes | FOXP3 | ||
T11201 | 191-196 | Protein | denotes | GATA3 | ||
T11202 | 246-251 | Protein | denotes | GATA3 | ||
T11203 | 330-340 | Negative_regulation | denotes | inhibiting | ||
T11204 | 341-346 | Protein | denotes | STAT4 | ||
T11205 | 347-357 | Gene_expression | denotes | expression | ||
T11206 | 380-385 | Protein | denotes | GATA3 | ||
T11207 | 450-455 | Protein | denotes | GATA3 | ||
T11208 | 469-476 | Negative_regulation | denotes | inhibit | true | |
T11209 | 477-482 | Protein | denotes | FOXP3 | ||
T11210 | 483-492 | Positive_regulation | denotes | induction | ||
T11211 | 508-513 | Protein | denotes | GATA3 | ||
T11212 | 529-534 | Protein | denotes | GATA3 | ||
T11213 | 535-542 | Negative_regulation | denotes | lacking | ||
T11214 | 547-565 | Entity | denotes | DNA-binding domain | ||
T11215 | 583-586 | Protein | denotes | CD4 | ||
T11216 | 587-593 | Protein | denotes | CD45RA | ||
T11217 | 611-651 | Protein | denotes | TAT-fused, recombinantly expressed GATA3 | ||
T11218 | 716-719 | Protein | denotes | CD3 | ||
T11219 | 720-724 | Protein | denotes | CD28 | ||
T11220 | 755-760 | Protein | denotes | TGF-β | ||
T11221 | 762-771 | Protein | denotes | TAT-GATA3 | ||
T11222 | 854-857 | Protein | denotes | CD4 | ||
T11223 | 893-902 | Protein | denotes | TAT-GATA3 | ||
T11224 | 903-910 | Negative_regulation | denotes | reduced | ||
T11225 | 911-916 | Protein | denotes | FOXP3 | ||
T11226 | 917-927 | Gene_expression | denotes | expression | ||
T11227 | 966-984 | Entity | denotes | DNA-binding domain | ||
T11228 | 985-994 | Negative_regulation | denotes | truncated | ||
T11229 | 1013-1018 | Protein | denotes | GATA3 | ||
T11230 | 1028-1034 | Regulation | denotes | affect | true | |
T11231 | 1035-1040 | Protein | denotes | FOXP3 | ||
T11232 | 1041-1051 | Gene_expression | denotes | expression | ||
T11233 | 1144-1161 | Negative_regulation | denotes | inhibitory effect | true | |
T11234 | 1165-1170 | Protein | denotes | GATA3 | ||
T11235 | 1174-1179 | Protein | denotes | FOXP3 | ||
T11236 | 1223-1237 | Positive_regulation | denotes | overexpressing | ||
T11237 | 1238-1243 | Protein | denotes | GATA3 | ||
T11238 | 1269-1272 | Protein | denotes | CD2 | ||
T11239 | 1303-1306 | Protein | denotes | CD2 | ||
T11240 | 1307-1312 | Protein | denotes | GATA3 | ||
T11241 | 1345-1348 | Protein | denotes | CD4 | ||
T11242 | 1386-1389 | Protein | denotes | CD2 | ||
T11243 | 1390-1395 | Protein | denotes | GATA3 | ||
T11244 | 1551-1557 | Regulation | denotes | effect | true | |
T11245 | 1561-1566 | Protein | denotes | GATA3 | ||
T11246 | 1577-1580 | Protein | denotes | CD4 | ||
T11247 | 1581-1586 | Protein | denotes | CD62L | ||
T11248 | 1587-1591 | Protein | denotes | CD25 | ||
T11249 | 1663-1668 | Protein | denotes | TGF-β | ||
T11250 | 1674-1679 | Protein | denotes | Foxp3 | ||
T11251 | 1680-1690 | Gene_expression | denotes | expression | true | |
T11252 | 1725-1728 | Protein | denotes | CD4 | ||
T11253 | 1729-1733 | Protein | denotes | CD25 | ||
T11254 | 1746-1751 | Protein | denotes | Foxp3 | ||
T11255 | 1807-1812 | Protein | denotes | TGF-β | ||
T11256 | 1826-1838 | Positive_regulation | denotes | up-regulated | ||
T11257 | 1839-1844 | Protein | denotes | Foxp3 | ||
T11258 | 1913-1916 | Protein | denotes | CD2 | ||
T11259 | 1917-1922 | Protein | denotes | GATA3 | ||
T11260 | 1956-1963 | Negative_regulation | denotes | reduced | ||
T11261 | 1964-1969 | Protein | denotes | Foxp3 | ||
T11262 | 1970-1980 | Gene_expression | denotes | expression | ||
T11263 | 1986-1995 | Positive_regulation | denotes | activated | ||
T11264 | 2001-2006 | Protein | denotes | TGF-β | ||
T11265 | 2037-2045 | Gene_expression | denotes | produced | ||
T11266 | 2065-2070 | Protein | denotes | TGF-β | ||
T11267 | 2085-2090 | Protein | denotes | Smad7 | ||
T11268 | 2103-2112 | Gene_expression | denotes | expressed | ||
T11269 | 2181-2186 | Protein | denotes | TGF-β | ||
T11270 | 3140-3144 | Protein | denotes | IL-4 | ||
T11271 | 3145-3152 | Positive_regulation | denotes | induced | ||
T11272 | 3153-3158 | Protein | denotes | GATA3 | ||
T26810 | 2208-2213 | Protein | denotes | GATA3 | ||
T26811 | 2246-2251 | Protein | denotes | FOXP3 | ||
T26812 | 2279-2282 | Protein | denotes | CD4 | ||
T26813 | 2283-2287 | Protein | denotes | CDRA | ||
T26814 | 2344-2353 | Protein | denotes | TAT-GATA3 | ||
T26815 | 2381-2389 | Gene_expression | denotes | presence | true | |
T26816 | 2393-2398 | Protein | denotes | GATA3 | ||
T26817 | 2438-2441 | Protein | denotes | CD3 | ||
T26818 | 2442-2446 | Protein | denotes | CD28 | ||
T26819 | 2472-2475 | Protein | denotes | GFP | ||
T26820 | 2533-2538 | Protein | denotes | FOXP3 | ||
T26821 | 2539-2549 | Gene_expression | denotes | expression | true | |
T26822 | 2660-2663 | Protein | denotes | CD4 | ||
T26823 | 2664-2668 | Protein | denotes | CD25 | ||
T26824 | 2717-2720 | Protein | denotes | CD2 | ||
T26825 | 2721-2726 | Protein | denotes | GATA3 | ||
T26826 | 2757-2762 | Protein | denotes | TGF-β | ||
T26827 | 2781-2784 | Protein | denotes | CD4 | ||
T26828 | 2803-2808 | Protein | denotes | FOXP3 | ||
T26829 | 2988-2993 | Protein | denotes | SMAD7 | ||
T26830 | 2998-3003 | Protein | denotes | TGF-β | ||
T26831 | 3004-3014 | Gene_expression | denotes | expression | true | |
T26832 | 3004-3014 | Gene_expression | denotes | expression | true | |
R8417 | T11187 | T11188 | causeOf | GATA3,Negative Regulator | ||
R8418 | T11189 | T11190 | themeOf | FOXP3,Expression | ||
R8419 | T11190 | T11188 | themeOf | Expression,Negative Regulator | ||
R8420 | T11191 | T11192 | themeOf | FOXP3,expression | ||
R8421 | T11192 | T11193 | themeOf | expression,decreased | ||
R8422 | T11194 | T11195 | themeOf | GATA3,expression | ||
R8423 | T11195 | T11193 | causeOf | expression,decreased | ||
R8424 | T11195 | T11196 | themeOf | expression,high | ||
R8425 | T11198 | T11197 | causeOf | GATA3,role | ||
R8426 | T11199 | T11197 | themeOf | repressing,role | ||
R8427 | T11200 | T11199 | themeOf | FOXP3,repressing | ||
R8428 | T11202 | T11203 | causeOf | GATA3,inhibiting | ||
R8429 | T11204 | T11205 | themeOf | STAT4,expression | ||
R8430 | T11205 | T11203 | themeOf | expression,inhibiting | ||
R8431 | T11207 | T11208 | causeOf | GATA3,inhibit | ||
R8432 | T11209 | T11210 | themeOf | FOXP3,induction | ||
R8433 | T11210 | T11208 | themeOf | induction,inhibit | ||
R8434 | T11214 | T11213 | themeOf | DNA-binding domain,lacking | ||
R8435 | T11214 | T11212 | partOf | DNA-binding domain,GATA3 | ||
R8436 | T11223 | T11224 | causeOf | TAT-GATA3,reduced | ||
R8437 | T11225 | T11226 | themeOf | FOXP3,expression | ||
R8438 | T11226 | T11224 | themeOf | expression,reduced | ||
R8439 | T11227 | T11228 | themeOf | DNA-binding domain,truncated | ||
R8440 | T11227 | T11229 | partOf | DNA-binding domain,GATA3 | ||
R8441 | T11228 | T11230 | causeOf | truncated,affect | ||
R8442 | T11231 | T11232 | themeOf | FOXP3,expression | ||
R8443 | T11232 | T11230 | themeOf | expression,affect | ||
R8444 | T11234 | T11233 | causeOf | GATA3,inhibitory effect | ||
R8445 | T11235 | T11233 | themeOf | FOXP3,inhibitory effect | ||
R8446 | T11237 | T11236 | themeOf | GATA3,overexpressing | ||
R8447 | T11245 | T11244 | causeOf | GATA3,effect | ||
R8448 | T11250 | T11251 | themeOf | Foxp3,expression | ||
R8449 | T11251 | T11244 | themeOf | expression,effect | ||
R8450 | T11255 | T11256 | causeOf | TGF-β,up-regulated | ||
R8451 | T11257 | T11256 | themeOf | Foxp3,up-regulated | ||
R8452 | T11259 | T11260 | causeOf | GATA3,reduced | ||
R8453 | T11261 | T11262 | themeOf | Foxp3,expression | ||
R8454 | T11262 | T11260 | themeOf | expression,reduced | ||
R8455 | T11262 | T11263 | themeOf | expression,activated | ||
R8456 | T11264 | T11263 | causeOf | TGF-β,activated | ||
R8457 | T11266 | T11265 | themeOf | TGF-β,produced | ||
R8458 | T11267 | T11268 | themeOf | Smad7,expressed | ||
R8459 | T11270 | T11271 | causeOf | IL-4,induced | ||
R8460 | T11272 | T11271 | themeOf | GATA3,induced | ||
R19787 | T26816 | T26815 | themeOf | GATA3,presence | ||
R19788 | T26820 | T26821 | themeOf | FOXP3,expression | ||
R19789 | T26829 | T26831 | themeOf | SMAD7,expression | ||
R19790 | T26830 | T26832 | themeOf | TGF-β,expression |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10850 | 0-5 | Protein | denotes | GATA3 |
T10851 | 33-38 | Protein | denotes | FOXP3 |
T10852 | 39-49 | Gene_expression | denotes | Expression |
T10853 | 20-29 | Negative_regulation | denotes | Regulator |
T10854 | 50-55 | Protein | denotes | FOXP3 |
T10855 | 82-87 | Protein | denotes | GATA3 |
T10856 | 156-161 | Protein | denotes | GATA3 |
T10857 | 176-181 | Protein | denotes | FOXP3 |
T10858 | 56-66 | Gene_expression | denotes | expression |
T10859 | 67-76 | Negative_regulation | denotes | decreased |
T10860 | 88-98 | Gene_expression | denotes | expression |
T10861 | 102-106 | Positive_regulation | denotes | high |
T10862 | 165-175 | Negative_regulation | denotes | repressing |
T10863 | 191-196 | Protein | denotes | GATA3 |
T10864 | 246-251 | Protein | denotes | GATA3 |
T10865 | 341-346 | Protein | denotes | STAT4 |
T10866 | 380-385 | Protein | denotes | GATA3 |
T10867 | 347-357 | Gene_expression | denotes | expression |
T10868 | 330-340 | Negative_regulation | denotes | inhibiting |
T10869 | 450-455 | Protein | denotes | GATA3 |
T10870 | 477-482 | Protein | denotes | FOXP3 |
T10871 | 508-513 | Protein | denotes | GATA3 |
T10872 | 529-534 | Protein | denotes | GATA3 |
T10873 | 583-587 | Protein | denotes | CD4+ |
T10874 | 646-651 | Protein | denotes | GATA3 |
T10875 | 483-492 | Positive_regulation | denotes | induction |
T10876 | 559-565 | Entity | denotes | domain |
T10877 | 636-645 | Gene_expression | denotes | expressed |
T10878 | 469-476 | Negative_regulation | denotes | inhibit |
T10879 | 535-542 | Negative_regulation | denotes | lacking |
T10880 | 716-719 | Protein | denotes | CD3 |
T10881 | 720-724 | Protein | denotes | CD28 |
T10882 | 755-760 | Protein | denotes | TGF-β |
T10883 | 762-765 | Protein | denotes | TAT |
T10884 | 766-771 | Protein | denotes | GATA3 |
T10885 | 893-896 | Protein | denotes | TAT |
T10886 | 897-902 | Protein | denotes | GATA3 |
T10887 | 911-916 | Protein | denotes | FOXP3 |
T10888 | 1004-1007 | Protein | denotes | TAT |
T10889 | 1008-1012 | Protein | denotes | ΔDBD |
T10890 | 1013-1018 | Protein | denotes | GATA3 |
T10891 | 1035-1040 | Protein | denotes | FOXP3 |
T10892 | 917-927 | Gene_expression | denotes | expression |
T10893 | 1041-1051 | Gene_expression | denotes | expression |
T10894 | 903-910 | Negative_regulation | denotes | reduced |
T10895 | 903-910 | Negative_regulation | denotes | reduced |
T10896 | 1028-1034 | Regulation | denotes | affect |
T10897 | 1165-1170 | Protein | denotes | GATA3 |
T10898 | 1174-1179 | Protein | denotes | FOXP3 |
T10899 | 1238-1243 | Protein | denotes | GATA3 |
T10900 | 1269-1278 | Protein | denotes | CD2 locus |
T10901 | 1223-1237 | Positive_regulation | denotes | overexpressing |
T10902 | 1345-1348 | Protein | denotes | CD4 |
T10903 | 1378-1382 | Protein | denotes | DO11 |
T10904 | 1383-1389 | Protein | denotes | 10xCD2 |
T10905 | 1390-1395 | Protein | denotes | GATA3 |
T10906 | 1561-1566 | Protein | denotes | GATA3 |
T10907 | 1570-1575 | Protein | denotes | iTreg |
T10908 | 1577-1580 | Protein | denotes | CD4 |
T10909 | 1581-1586 | Protein | denotes | CD62L |
T10910 | 1587-1591 | Protein | denotes | CD25 |
T10911 | 1663-1668 | Protein | denotes | TGF-β |
T10912 | 1674-1679 | Protein | denotes | Foxp3 |
T10913 | 1680-1690 | Gene_expression | denotes | expression |
T10914 | 1725-1728 | Protein | denotes | CD4 |
T10915 | 1729-1733 | Protein | denotes | CD25 |
T10916 | 1746-1751 | Protein | denotes | Foxp3 |
T10917 | 1807-1812 | Protein | denotes | TGF-β |
T10918 | 1839-1844 | Protein | denotes | Foxp3 |
T10919 | 1826-1838 | Positive_regulation | denotes | up-regulated |
T10920 | 1913-1916 | Protein | denotes | CD2 |
T10921 | 1917-1927 | Protein | denotes | GATA3xDO11 |
T10922 | 1964-1969 | Protein | denotes | Foxp3 |
T10923 | 2001-2006 | Protein | denotes | TGF-β |
T10924 | 1970-1980 | Gene_expression | denotes | expression |
T10925 | 1956-1963 | Negative_regulation | denotes | reduced |
T10926 | 2065-2070 | Protein | denotes | TGF-β |
T10927 | 2085-2090 | Protein | denotes | Smad7 |
T10928 | 2181-2186 | Protein | denotes | TGF-β |
T10929 | 2037-2045 | Gene_expression | denotes | produced |
T10930 | 2103-2112 | Gene_expression | denotes | expressed |
T10931 | 3140-3144 | Protein | denotes | IL-4 |
T10932 | 3153-3179 | Protein | denotes | GATA3 transcription factor |
T10933 | 3145-3152 | Positive_regulation | denotes | induced |
T26723 | 2208-2213 | Protein | denotes | GATA3 |
T26724 | 2246-2251 | Protein | denotes | FOXP3 |
T26725 | 2252-2262 | Gene_expression | denotes | Expression |
T26726 | 2279-2283 | Protein | denotes | CD4+ |
T26727 | 2344-2347 | Protein | denotes | TAT |
T26728 | 2348-2353 | Protein | denotes | GATA3 |
T26729 | 2393-2398 | Protein | denotes | GATA3 |
T26730 | 2438-2441 | Protein | denotes | CD3 |
T26731 | 2442-2446 | Protein | denotes | CD28 |
T26732 | 2381-2389 | Negative_regulation | denotes | presence |
T26733 | 2533-2538 | Protein | denotes | FOXP3 |
T26734 | 2539-2549 | Gene_expression | denotes | expression |
T26735 | 2660-2663 | Protein | denotes | CD4 |
T26736 | 2664-2668 | Protein | denotes | CD25 |
T26737 | 2757-2762 | Protein | denotes | TGF-β |
T26738 | 2781-2784 | Protein | denotes | CD4 |
T26739 | 2988-2993 | Protein | denotes | SMAD7 |
T26740 | 2998-3003 | Protein | denotes | TGF-β |
T26741 | 3004-3014 | Gene_expression | denotes | expression |
T26742 | 3004-3014 | Gene_expression | denotes | expression |
R8262 | T10850 | T10853 | causeOf | GATA3,Regulator |
R8263 | T10851 | T10852 | themeOf | FOXP3,Expression |
R8264 | T10852 | T10853 | themeOf | Expression,Regulator |
R8265 | T10854 | T10858 | themeOf | FOXP3,expression |
R8266 | T10855 | T10860 | themeOf | GATA3,expression |
R8267 | T10857 | T10862 | themeOf | FOXP3,repressing |
R8268 | T10858 | T10859 | themeOf | expression,decreased |
R8269 | T10860 | T10861 | themeOf | expression,high |
R8270 | T10865 | T10867 | themeOf | STAT4,expression |
R8271 | T10867 | T10868 | themeOf | expression,inhibiting |
R8272 | T10869 | T10878 | causeOf | GATA3,inhibit |
R8273 | T10870 | T10875 | themeOf | FOXP3,induction |
R8274 | T10872 | T10879 | themeOf | GATA3,lacking |
R8275 | T10874 | T10877 | themeOf | GATA3,expressed |
R8276 | T10875 | T10878 | themeOf | induction,inhibit |
R8277 | T10876 | T10879 | Site | domain,lacking |
R8278 | T10885 | T10894 | causeOf | TAT,reduced |
R8279 | T10886 | T10895 | causeOf | GATA3,reduced |
R8280 | T10887 | T10892 | themeOf | FOXP3,expression |
R8281 | T10891 | T10893 | themeOf | FOXP3,expression |
R8282 | T10892 | T10894 | themeOf | expression,reduced |
R8283 | T10892 | T10895 | themeOf | expression,reduced |
R8284 | T10893 | T10896 | themeOf | expression,affect |
R8285 | T10899 | T10901 | themeOf | GATA3,overexpressing |
R8286 | T10912 | T10913 | themeOf | Foxp3,expression |
R8287 | T10917 | T10919 | causeOf | TGF-β,up-regulated |
R8288 | T10918 | T10919 | themeOf | Foxp3,up-regulated |
R8289 | T10922 | T10924 | themeOf | Foxp3,expression |
R8290 | T10924 | T10925 | themeOf | expression,reduced |
R8291 | T10926 | T10929 | themeOf | TGF-β,produced |
R8292 | T10927 | T10930 | themeOf | Smad7,expressed |
R8293 | T10931 | T10933 | causeOf | IL-4,induced |
R8294 | T10932 | T10933 | themeOf | GATA3 transcription factor,induced |
R19771 | T26724 | T26725 | themeOf | FOXP3,Expression |
R19772 | T26729 | T26732 | themeOf | GATA3,presence |
R19773 | T26733 | T26734 | themeOf | FOXP3,expression |
R19774 | T26739 | T26741 | themeOf | SMAD7,expression |
R19775 | T26740 | T26742 | themeOf | TGF-β,expression |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T9761 | 88-98 | Gene_expression | denotes | expression | ||
T9762 | 102-106 | Positive_regulation | denotes | high | ||
T9763 | 147-151 | Regulation | denotes | role | true | |
T9764 | 156-161 | Protein | denotes | GATA3 | ||
T9765 | 165-175 | Negative_regulation | denotes | repressing | ||
T9766 | 176-181 | Protein | denotes | FOXP3 | ||
T9767 | 191-196 | Protein | denotes | GATA3 | ||
T9768 | 246-251 | Protein | denotes | GATA3 | ||
T9769 | 330-340 | Negative_regulation | denotes | inhibiting | ||
T9770 | 341-346 | Protein | denotes | STAT4 | ||
T9771 | 347-357 | Gene_expression | denotes | expression | ||
T9772 | 380-385 | Protein | denotes | GATA3 | ||
T9773 | 450-455 | Protein | denotes | GATA3 | ||
T9774 | 469-476 | Negative_regulation | denotes | inhibit | true | |
T9775 | 477-482 | Protein | denotes | FOXP3 | ||
T9776 | 483-492 | Positive_regulation | denotes | induction | ||
T9777 | 508-513 | Protein | denotes | GATA3 | ||
T9778 | 529-534 | Protein | denotes | GATA3 | ||
T9779 | 535-542 | Negative_regulation | denotes | lacking | ||
T9780 | 547-565 | Entity | denotes | DNA-binding domain | ||
T9781 | 583-586 | Protein | denotes | CD4 | ||
T9782 | 587-593 | Protein | denotes | CD45RA | ||
T9783 | 611-651 | Protein | denotes | TAT-fused, recombinantly expressed GATA3 | ||
T9784 | 716-719 | Protein | denotes | CD3 | ||
T9785 | 720-724 | Protein | denotes | CD28 | ||
T9786 | 755-760 | Protein | denotes | TGF-β | ||
T9787 | 762-771 | Protein | denotes | TAT-GATA3 | ||
T9788 | 854-857 | Protein | denotes | CD4 | ||
T9789 | 893-902 | Protein | denotes | TAT-GATA3 | ||
T9790 | 903-910 | Negative_regulation | denotes | reduced | ||
T9791 | 911-916 | Protein | denotes | FOXP3 | ||
T9792 | 917-927 | Gene_expression | denotes | expression | ||
T9793 | 966-984 | Entity | denotes | DNA-binding domain | ||
T9794 | 985-994 | Negative_regulation | denotes | truncated | ||
T9795 | 1013-1018 | Protein | denotes | GATA3 | ||
T9796 | 1028-1034 | Regulation | denotes | affect | true | |
T9797 | 1035-1040 | Protein | denotes | FOXP3 | ||
T9798 | 1041-1051 | Gene_expression | denotes | expression | ||
T9799 | 1144-1161 | Negative_regulation | denotes | inhibitory effect | true | |
T9800 | 1165-1170 | Protein | denotes | GATA3 | ||
T9801 | 1174-1179 | Protein | denotes | FOXP3 | ||
T9802 | 1223-1237 | Positive_regulation | denotes | overexpressing | ||
T9803 | 1238-1243 | Protein | denotes | GATA3 | ||
T9804 | 1269-1272 | Protein | denotes | CD2 | ||
T9805 | 1303-1306 | Protein | denotes | CD2 | ||
T9806 | 1307-1312 | Protein | denotes | GATA3 | ||
T9807 | 1345-1348 | Protein | denotes | CD4 | ||
T9808 | 1386-1389 | Protein | denotes | CD2 | ||
T9809 | 1390-1395 | Protein | denotes | GATA3 | ||
T9810 | 1551-1557 | Regulation | denotes | effect | true | |
T9811 | 1561-1566 | Protein | denotes | GATA3 | ||
T9812 | 1577-1580 | Protein | denotes | CD4 | ||
T9813 | 1581-1586 | Protein | denotes | CD62L | ||
T9814 | 1587-1591 | Protein | denotes | CD25 | ||
T9815 | 1663-1668 | Protein | denotes | TGF-β | ||
T9816 | 1674-1679 | Protein | denotes | Foxp3 | ||
T9817 | 1680-1690 | Gene_expression | denotes | expression | true | |
T9818 | 1725-1728 | Protein | denotes | CD4 | ||
T9819 | 1729-1733 | Protein | denotes | CD25 | ||
T9820 | 1746-1751 | Protein | denotes | Foxp3 | ||
T9821 | 1807-1812 | Protein | denotes | TGF-β | ||
T9822 | 1826-1838 | Positive_regulation | denotes | up-regulated | ||
T9823 | 1839-1844 | Protein | denotes | Foxp3 | ||
T9824 | 1913-1916 | Protein | denotes | CD2 | ||
T9825 | 1917-1922 | Protein | denotes | GATA3 | ||
T9826 | 1956-1963 | Negative_regulation | denotes | reduced | ||
T9827 | 1964-1969 | Protein | denotes | Foxp3 | ||
T9828 | 1970-1980 | Gene_expression | denotes | expression | ||
T9829 | 1986-1995 | Positive_regulation | denotes | activated | ||
T9830 | 2001-2006 | Protein | denotes | TGF-β | ||
T9831 | 2037-2045 | Gene_expression | denotes | produced | ||
T9832 | 2065-2070 | Protein | denotes | TGF-β | ||
T9833 | 2085-2090 | Protein | denotes | Smad7 | ||
T9834 | 2103-2112 | Gene_expression | denotes | expressed | ||
T9835 | 2181-2186 | Protein | denotes | TGF-β | ||
T9836 | 3140-3144 | Protein | denotes | IL-4 | ||
T9837 | 3145-3152 | Positive_regulation | denotes | induced | ||
T9838 | 3153-3158 | Protein | denotes | GATA3 | ||
T9753 | 0-5 | Protein | denotes | GATA3 | ||
T9754 | 11-29 | Negative_regulation | denotes | Negative Regulator | ||
T9755 | 33-38 | Protein | denotes | FOXP3 | ||
T9756 | 39-49 | Gene_expression | denotes | Expression | ||
T9757 | 50-55 | Protein | denotes | FOXP3 | ||
T9758 | 56-66 | Gene_expression | denotes | expression | ||
T9759 | 67-76 | Negative_regulation | denotes | decreased | ||
T9760 | 82-87 | Protein | denotes | GATA3 | ||
T26314 | 2208-2213 | Protein | denotes | GATA3 | ||
T26315 | 2246-2251 | Protein | denotes | FOXP3 | ||
T26316 | 2279-2282 | Protein | denotes | CD4 | ||
T26317 | 2283-2287 | Protein | denotes | CDRA | ||
T26318 | 2344-2353 | Protein | denotes | TAT-GATA3 | ||
T26319 | 2381-2389 | Gene_expression | denotes | presence | true | |
T26320 | 2393-2398 | Protein | denotes | GATA3 | ||
T26321 | 2438-2441 | Protein | denotes | CD3 | ||
T26322 | 2442-2446 | Protein | denotes | CD28 | ||
T26323 | 2472-2475 | Protein | denotes | GFP | ||
T26324 | 2533-2538 | Protein | denotes | FOXP3 | ||
T26325 | 2539-2549 | Gene_expression | denotes | expression | true | |
T26326 | 2660-2663 | Protein | denotes | CD4 | ||
T26327 | 2664-2668 | Protein | denotes | CD25 | ||
T26328 | 2717-2720 | Protein | denotes | CD2 | ||
T26329 | 2721-2726 | Protein | denotes | GATA3 | ||
T26330 | 2757-2762 | Protein | denotes | TGF-β | ||
T26331 | 2781-2784 | Protein | denotes | CD4 | ||
T26332 | 2803-2808 | Protein | denotes | FOXP3 | ||
T26333 | 2988-2993 | Protein | denotes | SMAD7 | ||
T26334 | 2998-3003 | Protein | denotes | TGF-β | ||
T26335 | 3004-3014 | Gene_expression | denotes | expression | true | |
T26336 | 3004-3014 | Gene_expression | denotes | expression | true | |
R7379 | T9753 | T9754 | causeOf | GATA3,Negative Regulator | ||
R7380 | T9755 | T9756 | themeOf | FOXP3,Expression | ||
R7381 | T9756 | T9754 | themeOf | Expression,Negative Regulator | ||
R7387 | T9764 | T9763 | causeOf | GATA3,role | ||
R7389 | T9766 | T9765 | themeOf | FOXP3,repressing | ||
R7390 | T9768 | T9769 | causeOf | GATA3,inhibiting | ||
R7391 | T9770 | T9771 | themeOf | STAT4,expression | ||
R7392 | T9771 | T9769 | themeOf | expression,inhibiting | ||
R7393 | T9773 | T9774 | causeOf | GATA3,inhibit | ||
R7394 | T9775 | T9776 | themeOf | FOXP3,induction | ||
R7395 | T9776 | T9774 | themeOf | induction,inhibit | ||
R7396 | T9780 | T9779 | themeOf | DNA-binding domain,lacking | ||
R7397 | T9780 | T9778 | partOf | DNA-binding domain,GATA3 | ||
R7398 | T9789 | T9790 | causeOf | TAT-GATA3,reduced | ||
R7399 | T9791 | T9792 | themeOf | FOXP3,expression | ||
R7400 | T9792 | T9790 | themeOf | expression,reduced | ||
R7401 | T9793 | T9794 | themeOf | DNA-binding domain,truncated | ||
R7402 | T9793 | T9795 | partOf | DNA-binding domain,GATA3 | ||
R7403 | T9794 | T9796 | causeOf | truncated,affect | ||
R7404 | T9797 | T9798 | themeOf | FOXP3,expression | ||
R7405 | T9798 | T9796 | themeOf | expression,affect | ||
R7406 | T9800 | T9799 | causeOf | GATA3,inhibitory effect | ||
R7407 | T9801 | T9799 | themeOf | FOXP3,inhibitory effect | ||
R7408 | T9803 | T9802 | themeOf | GATA3,overexpressing | ||
R7382 | T9757 | T9758 | themeOf | FOXP3,expression | ||
R7383 | T9758 | T9759 | themeOf | expression,decreased | ||
R7384 | T9760 | T9761 | themeOf | GATA3,expression | ||
R7385 | T9761 | T9759 | causeOf | expression,decreased | ||
R7386 | T9761 | T9762 | themeOf | expression,high | ||
R7388 | T9765 | T9763 | themeOf | repressing,role | ||
R7409 | T9811 | T9810 | causeOf | GATA3,effect | ||
R7410 | T9816 | T9817 | themeOf | Foxp3,expression | ||
R7411 | T9817 | T9810 | themeOf | expression,effect | ||
R7412 | T9821 | T9822 | causeOf | TGF-β,up-regulated | ||
R7413 | T9823 | T9822 | themeOf | Foxp3,up-regulated | ||
R7414 | T9825 | T9826 | causeOf | GATA3,reduced | ||
R7415 | T9827 | T9828 | themeOf | Foxp3,expression | ||
R7416 | T9828 | T9826 | themeOf | expression,reduced | ||
R7417 | T9828 | T9829 | themeOf | expression,activated | ||
R7418 | T9830 | T9829 | causeOf | TGF-β,activated | ||
R7419 | T9832 | T9831 | themeOf | TGF-β,produced | ||
R7420 | T9833 | T9834 | themeOf | Smad7,expressed | ||
R7421 | T9836 | T9837 | causeOf | IL-4,induced | ||
R7422 | T9838 | T9837 | themeOf | GATA3,induced | ||
R19447 | T26320 | T26319 | themeOf | GATA3,presence | ||
R19448 | T26324 | T26325 | themeOf | FOXP3,expression | ||
R19449 | T26333 | T26335 | themeOf | SMAD7,expression | ||
R19450 | T26334 | T26336 | themeOf | TGF-β,expression |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10245 | 0-5 | P23771 | denotes | GATA3 |
T10246 | 33-38 | Q9BZS1 | denotes | FOXP3 |
T10247 | 50-55 | Q9BZS1 | denotes | FOXP3 |
T10248 | 82-87 | P23771 | denotes | GATA3 |
T10249 | 156-161 | P23771 | denotes | GATA3 |
T10250 | 176-181 | Q9BZS1 | denotes | FOXP3 |
T10251 | 191-196 | P23771 | denotes | GATA3 |
T10252 | 246-251 | P23771 | denotes | GATA3 |
T10253 | 341-346 | Q14765 | denotes | STAT4 |
T10254 | 380-385 | P23771 | denotes | GATA3 |
T10255 | 450-455 | P23771 | denotes | GATA3 |
T10256 | 477-482 | Q9BZS1 | denotes | FOXP3 |
T10257 | 508-513 | P23771 | denotes | GATA3 |
T10258 | 529-534 | P23771 | denotes | GATA3 |
T10259 | 583-586 | P01730 | denotes | CD4 |
T10260 | 587-593 | P08575 | denotes | CD45RA |
T10261 | 611-614 | P04608 | denotes | TAT |
T10262 | 611-614 | Q8UMQ1 | denotes | TAT |
T10263 | 611-614 | P04610 | denotes | TAT |
T10264 | 611-614 | P04605 | denotes | TAT |
T10265 | 646-651 | P23771 | denotes | GATA3 |
T10266 | 716-719 | P09693 | denotes | CD3 |
T10267 | 716-719 | P04234 | denotes | CD3 |
T10268 | 716-719 | P07766 | denotes | CD3 |
T10269 | 716-719 | P20963 | denotes | CD3 |
T10270 | 720-724 | P10747 | denotes | CD28 |
T10271 | 755-760 | P01137 | denotes | TGF-β |
T10272 | 762-765 | P04608 | denotes | TAT |
T10273 | 762-765 | P04605 | denotes | TAT |
T10274 | 762-765 | Q8UMQ1 | denotes | TAT |
T10275 | 762-765 | P04610 | denotes | TAT |
T10276 | 766-771 | P23771 | denotes | GATA3 |
T10277 | 854-857 | P01730 | denotes | CD4 |
T10278 | 893-896 | P04605 | denotes | TAT |
T10279 | 893-896 | P04608 | denotes | TAT |
T10280 | 893-896 | P04610 | denotes | TAT |
T10281 | 893-896 | Q8UMQ1 | denotes | TAT |
T10282 | 897-902 | P23771 | denotes | GATA3 |
T10283 | 911-916 | Q9BZS1 | denotes | FOXP3 |
T10284 | 1004-1007 | P04605 | denotes | TAT |
T10285 | 1004-1007 | P04608 | denotes | TAT |
T10286 | 1004-1007 | P04610 | denotes | TAT |
T10287 | 1004-1007 | Q8UMQ1 | denotes | TAT |
T10288 | 1013-1018 | P23771 | denotes | GATA3 |
T10289 | 1035-1040 | Q9BZS1 | denotes | FOXP3 |
T10290 | 1165-1170 | P23771 | denotes | GATA3 |
T10291 | 1174-1179 | Q9BZS1 | denotes | FOXP3 |
T10292 | 1238-1243 | P23771 | denotes | GATA3 |
T10293 | 1269-1272 | P06729 | denotes | CD2 |
T10294 | 1307-1312 | P23771 | denotes | GATA3 |
T10295 | 1345-1348 | P01730 | denotes | CD4 |
T10296 | 1390-1395 | P23771 | denotes | GATA3 |
T10297 | 1561-1566 | P23771 | denotes | GATA3 |
T10298 | 1577-1580 | P01730 | denotes | CD4 |
T10299 | 1581-1586 | P14151 | denotes | CD62L |
T10300 | 1587-1591 | P01589 | denotes | CD25 |
T10301 | 1629-1632 | E2RVI8 | denotes | OVA |
T10302 | 1663-1668 | P01137 | denotes | TGF-β |
T10303 | 1674-1679 | Q9BZS1 | denotes | Foxp3 |
T10304 | 1725-1728 | P01730 | denotes | CD4 |
T10305 | 1729-1733 | P01589 | denotes | CD25 |
T10306 | 1746-1751 | Q9BZS1 | denotes | Foxp3 |
T10307 | 1807-1812 | P01137 | denotes | TGF-β |
T10308 | 1839-1844 | Q9BZS1 | denotes | Foxp3 |
T10309 | 1913-1916 | P06729 | denotes | CD2 |
T10310 | 1964-1969 | Q9BZS1 | denotes | Foxp3 |
T10311 | 2001-2006 | P01137 | denotes | TGF-β |
T10312 | 2011-2014 | E2RVI8 | denotes | OVA |
T10313 | 2065-2070 | P01137 | denotes | TGF-β |
T10314 | 2181-2186 | P01137 | denotes | TGF-β |
T10315 | 3140-3144 | P05112 | denotes | IL-4 |
T10316 | 3153-3158 | P23771 | denotes | GATA3 |
T26495 | 2208-2213 | P23771 | denotes | GATA3 |
T26496 | 2246-2251 | Q9BZS1 | denotes | FOXP3 |
T26497 | 2279-2282 | P01730 | denotes | CD4 |
T26498 | 2344-2347 | P04608 | denotes | TAT |
T26499 | 2344-2347 | P04610 | denotes | TAT |
T26500 | 2344-2347 | P04605 | denotes | TAT |
T26501 | 2344-2347 | Q8UMQ1 | denotes | TAT |
T26502 | 2348-2353 | P23771 | denotes | GATA3 |
T26503 | 2393-2398 | P23771 | denotes | GATA3 |
T26504 | 2438-2441 | P04234 | denotes | CD3 |
T26505 | 2438-2441 | P07766 | denotes | CD3 |
T26506 | 2438-2441 | P20963 | denotes | CD3 |
T26507 | 2438-2441 | P09693 | denotes | CD3 |
T26508 | 2442-2446 | P10747 | denotes | CD28 |
T26509 | 2472-2475 | Q9U6Y4 | denotes | GFP |
T26510 | 2533-2538 | Q9BZS1 | denotes | FOXP3 |
T26511 | 2660-2663 | P01730 | denotes | CD4 |
T26512 | 2664-2668 | P01589 | denotes | CD25 |
T26513 | 2721-2726 | P23771 | denotes | GATA3 |
T26514 | 2749-2752 | E2RVI8 | denotes | OVA |
T26515 | 2757-2762 | P01137 | denotes | TGF-β |
T26516 | 2781-2784 | P01730 | denotes | CD4 |
T26517 | 2803-2808 | Q9BZS1 | denotes | FOXP3 |
T26518 | 2998-3003 | P01137 | denotes | TGF-β |
test2
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T9665 | 0-5 | Protein | denotes | GATA3 | ||
T9666 | 20-29 | Regulation | denotes | Regulator | ||
T9667 | 33-38 | Protein | denotes | FOXP3 | ||
T9668 | 39-49 | Gene_expression | denotes | Expression | ||
T9669 | 50-55 | Protein | denotes | FOXP3 | ||
T9670 | 56-66 | Gene_expression | denotes | expression | ||
T9671 | 67-76 | Negative_regulation | denotes | decreased | true | |
T9672 | 82-87 | Protein | denotes | GATA3 | ||
T9673 | 88-98 | Gene_expression | denotes | expression | ||
T9674 | 147-151 | Regulation | denotes | role | ||
T9675 | 156-161 | Protein | denotes | GATA3 | true | |
T9676 | 165-175 | Negative_regulation | denotes | repressing | ||
T9677 | 176-181 | Protein | denotes | FOXP3 | ||
T9678 | 191-196 | Protein | denotes | GATA3 | ||
T9679 | 246-251 | Protein | denotes | GATA3 | ||
T9680 | 330-340 | Negative_regulation | denotes | inhibiting | ||
T9681 | 341-346 | Protein | denotes | STAT4 | true | |
T9682 | 347-357 | Gene_expression | denotes | expression | ||
T9683 | 380-385 | Protein | denotes | GATA3 | true | |
T9684 | 450-455 | Protein | denotes | GATA3 | ||
T9685 | 469-476 | Negative_regulation | denotes | inhibit | true | |
T9686 | 477-482 | Protein | denotes | FOXP3 | true | |
T9687 | 483-492 | Positive_regulation | denotes | induction | ||
T9688 | 497-507 | Positive_regulation | denotes | transduced | ||
T9689 | 508-513 | Protein | denotes | GATA3 | ||
T9690 | 519-528 | Negative_regulation | denotes | truncated | ||
T9691 | 529-534 | Protein | denotes | GATA3 | ||
T9692 | 535-542 | Negative_regulation | denotes | lacking | ||
T9693 | 547-565 | Entity | denotes | DNA-binding domain | ||
T9694 | 583-586 | Protein | denotes | CD4 | ||
T9695 | 587-593 | Protein | denotes | CD45RA | ||
T9696 | 611-651 | Protein | denotes | TAT-fused, recombinantly expressed GATA3 | ||
T9697 | 716-719 | Protein | denotes | CD3 | ||
T9698 | 720-724 | Protein | denotes | CD28 | ||
T9699 | 744-751 | Negative_regulation | denotes | absence | ||
T9700 | 755-760 | Protein | denotes | TGF-β | ||
T9701 | 762-771 | Protein | denotes | TAT-GATA3 | ||
T9702 | 854-857 | Protein | denotes | CD4 | ||
T9703 | 893-902 | Protein | denotes | TAT-GATA3 | ||
T9704 | 903-910 | Negative_regulation | denotes | reduced | ||
T9705 | 911-916 | Protein | denotes | FOXP3 | ||
T9706 | 917-927 | Gene_expression | denotes | expression | ||
T9707 | 938-947 | Regulation | denotes | dependent | ||
T9708 | 966-984 | Entity | denotes | DNA-binding domain | ||
T9709 | 1013-1018 | Protein | denotes | GATA3 | ||
T9710 | 1028-1034 | Regulation | denotes | affect | ||
T9711 | 1035-1040 | Protein | denotes | FOXP3 | ||
T9712 | 1041-1051 | Gene_expression | denotes | expression | ||
T9713 | 1069-1079 | Gene_expression | denotes | expression | ||
T9714 | 1155-1161 | Regulation | denotes | effect | ||
T9715 | 1165-1170 | Protein | denotes | GATA3 | ||
T9716 | 1174-1179 | Protein | denotes | FOXP3 | ||
T9717 | 1223-1237 | Positive_regulation | denotes | overexpressing | ||
T9718 | 1238-1243 | Protein | denotes | GATA3 | ||
T9719 | 1269-1272 | Protein | denotes | CD2 | ||
T9720 | 1300-1306 | Protein | denotes | 10xCD2 | ||
T9721 | 1307-1312 | Protein | denotes | GATA3 | ||
T9722 | 1345-1348 | Protein | denotes | CD4 | ||
T9723 | 1383-1389 | Protein | denotes | 10xCD2 | ||
T9724 | 1390-1395 | Protein | denotes | GATA3 | ||
T9725 | 1561-1566 | Protein | denotes | GATA3 | ||
T9726 | 1577-1580 | Protein | denotes | CD4 | ||
T9727 | 1581-1586 | Protein | denotes | CD62L | ||
T9728 | 1587-1591 | Protein | denotes | CD25 | ||
T9729 | 1663-1668 | Protein | denotes | TGF-β | ||
T9730 | 1674-1679 | Protein | denotes | Foxp3 | ||
T9731 | 1680-1690 | Gene_expression | denotes | expression | ||
T9732 | 1725-1728 | Protein | denotes | CD4 | ||
T9733 | 1729-1733 | Protein | denotes | CD25 | ||
T9734 | 1746-1751 | Protein | denotes | Foxp3 | ||
T9735 | 1807-1812 | Protein | denotes | TGF-β | ||
T9736 | 1826-1838 | Positive_regulation | denotes | up-regulated | ||
T9737 | 1839-1844 | Protein | denotes | Foxp3 | ||
T9738 | 1913-1916 | Protein | denotes | CD2 | ||
T9739 | 1917-1927 | Protein | denotes | GATA3xDO11 | ||
T9740 | 1956-1963 | Negative_regulation | denotes | reduced | ||
T9741 | 1964-1969 | Protein | denotes | Foxp3 | ||
T9742 | 1970-1980 | Gene_expression | denotes | expression | ||
T9743 | 1986-1995 | Positive_regulation | denotes | activated | ||
T9744 | 2001-2006 | Protein | denotes | TGF-β | ||
T9745 | 2037-2045 | Gene_expression | denotes | produced | ||
T9746 | 2065-2070 | Protein | denotes | TGF-β | ||
T9747 | 2085-2090 | Protein | denotes | Smad7 | ||
T9748 | 2103-2112 | Gene_expression | denotes | expressed | ||
T9749 | 2181-2186 | Protein | denotes | TGF-β | ||
T9750 | 3140-3144 | Protein | denotes | IL-4 | ||
T9751 | 3145-3152 | Positive_regulation | denotes | induced | ||
T9752 | 3153-3158 | Protein | denotes | GATA3 | ||
T26290 | 2208-2213 | Protein | denotes | GATA3 | true | |
T26291 | 2224-2242 | Negative_regulation | denotes | Negative Regulator | true | |
T26292 | 2246-2251 | Protein | denotes | FOXP3 | true | |
T26293 | 2252-2262 | Gene_expression | denotes | Expression | true | |
T26294 | 2279-2282 | Protein | denotes | CD4 | ||
T26295 | 2283-2287 | Protein | denotes | CDRA | ||
T26296 | 2344-2353 | Protein | denotes | TAT-GATA3 | ||
T26297 | 2393-2398 | Protein | denotes | GATA3 | ||
T26298 | 2438-2441 | Protein | denotes | CD3 | ||
T26299 | 2442-2446 | Protein | denotes | CD28 | ||
T26300 | 2472-2475 | Protein | denotes | GFP | ||
T26301 | 2533-2538 | Protein | denotes | FOXP3 | ||
T26302 | 2539-2549 | Gene_expression | denotes | expression | ||
T26303 | 2550-2559 | Positive_regulation | denotes | following | ||
T26304 | 2660-2663 | Protein | denotes | CD4 | ||
T26305 | 2664-2668 | Protein | denotes | CD25 | ||
T26306 | 2714-2720 | Protein | denotes | 10xCD2 | ||
T26307 | 2721-2726 | Protein | denotes | GATA3 | ||
T26308 | 2757-2762 | Protein | denotes | TGF-β | ||
T26309 | 2781-2784 | Protein | denotes | CD4 | ||
T26310 | 2803-2808 | Protein | denotes | FOXP3 | ||
T26311 | 2988-2993 | Protein | denotes | SMAD7 | ||
T26312 | 2998-3003 | Protein | denotes | TGF-β | ||
T26313 | 3004-3014 | Gene_expression | denotes | expression | ||
R7339 | T9667 | T9668 | themeOf | FOXP3,Expression | ||
R7340 | T9669 | T9670 | themeOf | FOXP3,expression | ||
R7341 | T9670 | T9671 | themeOf | expression,decreased | ||
R7342 | T9672 | T9673 | themeOf | GATA3,expression | ||
R7343 | T9673 | T9671 | causeOf | expression,decreased | ||
R7344 | T9675 | T9674 | causeOf | GATA3,role | ||
R7345 | T9677 | T9676 | themeOf | FOXP3,repressing | ||
R7346 | T9678 | T9680 | causeOf | GATA3,inhibiting | ||
R7347 | T9679 | T9680 | causeOf | GATA3,inhibiting | ||
R7348 | T9681 | T9682 | themeOf | STAT4,expression | ||
R7349 | T9682 | T9680 | themeOf | expression,inhibiting | ||
R7350 | T9684 | T9685 | causeOf | GATA3,inhibit | ||
R7351 | T9686 | T9687 | themeOf | FOXP3,induction | ||
R7352 | T9687 | T9685 | themeOf | induction,inhibit | ||
R7353 | T9689 | T9688 | themeOf | GATA3,transduced | ||
R7354 | T9693 | T9691 | partOf | DNA-binding domain,GATA3 | ||
R7355 | T9693 | T9692 | themeOf | DNA-binding domain,lacking | ||
R7356 | T9700 | T9699 | themeOf | TGF-β,absence | ||
R7357 | T9703 | T9704 | causeOf | TAT-GATA3,reduced | ||
R7358 | T9704 | T9707 | themeOf | reduced,dependent | ||
R7359 | T9705 | T9706 | themeOf | FOXP3,expression | ||
R7360 | T9706 | T9704 | themeOf | expression,reduced | ||
R7361 | T9708 | T9709 | partOf | DNA-binding domain,GATA3 | ||
R7362 | T9711 | T9712 | themeOf | FOXP3,expression | ||
R7363 | T9712 | T9710 | themeOf | expression,affect | ||
R7364 | T9718 | T9717 | themeOf | GATA3,overexpressing | ||
R7365 | T9729 | T9731 | themeOf | TGF-β,expression | ||
R7366 | T9730 | T9731 | themeOf | Foxp3,expression | ||
R7367 | T9735 | T9736 | causeOf | TGF-β,up-regulated | ||
R7368 | T9737 | T9736 | themeOf | Foxp3,up-regulated | ||
R7369 | T9739 | T9740 | causeOf | GATA3xDO11,reduced | ||
R7370 | T9741 | T9742 | themeOf | Foxp3,expression | ||
R7371 | T9742 | T9740 | themeOf | expression,reduced | ||
R7372 | T9742 | T9743 | themeOf | expression,activated | ||
R7373 | T9744 | T9743 | causeOf | TGF-β,activated | ||
R7374 | T9746 | T9745 | themeOf | TGF-β,produced | ||
R7375 | T9747 | T9745 | themeOf | Smad7,produced | ||
R7376 | T9747 | T9748 | themeOf | Smad7,expressed | ||
R7377 | T9750 | T9751 | causeOf | IL-4,induced | ||
R7378 | T9752 | T9751 | themeOf | GATA3,induced | ||
R19442 | T26292 | T26293 | themeOf | FOXP3,Expression | ||
R19443 | T26293 | T26291 | themeOf | Expression,Negative Regulator | ||
R19444 | T26301 | T26302 | themeOf | FOXP3,expression | ||
R19445 | T26311 | T26313 | themeOf | SMAD7,expression | ||
R19446 | T26312 | T26313 | themeOf | TGF-β,expression |