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PMC:2065877 / 1040-1734 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T11 0-157 Sentence denotes Epstein-Barr virus (EBV) is linked to the development of multiple cancers, including post-transplant lymphoma, Hodgkin disease, and nasopharyngeal carcinoma.
T12 158-339 Sentence denotes Latent membrane protein 1 (LMP1) is expressed in many EBV-associated cancers and is responsible for most of the altered cellular growth properties that are induced by EBV infection.
T13 340-471 Sentence denotes This study reveals that LMP1 induces lymphomas in B-1a lymphocytes, a cell type that is susceptible to transformation in aged mice.
T14 472-558 Sentence denotes The lymphomas require Akt, NFκB, and Stat3 signaling for enhanced growth and survival.
T15 559-694 Sentence denotes The activation of the Stat3, Akt, and NFκB signaling pathways likely underlies the ability of LMP1 to promote malignant transformation.