| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T10 |
0-14 |
Sentence |
denotes |
Author Summary |
| T11 |
16-173 |
Sentence |
denotes |
Epstein-Barr virus (EBV) is linked to the development of multiple cancers, including post-transplant lymphoma, Hodgkin disease, and nasopharyngeal carcinoma. |
| T12 |
174-355 |
Sentence |
denotes |
Latent membrane protein 1 (LMP1) is expressed in many EBV-associated cancers and is responsible for most of the altered cellular growth properties that are induced by EBV infection. |
| T13 |
356-487 |
Sentence |
denotes |
This study reveals that LMP1 induces lymphomas in B-1a lymphocytes, a cell type that is susceptible to transformation in aged mice. |
| T14 |
488-574 |
Sentence |
denotes |
The lymphomas require Akt, NFκB, and Stat3 signaling for enhanced growth and survival. |
| T15 |
575-710 |
Sentence |
denotes |
The activation of the Stat3, Akt, and NFκB signaling pathways likely underlies the ability of LMP1 to promote malignant transformation. |
