Id |
Subject |
Object |
Predicate |
Lexical cue |
T6116 |
0-7 |
NN |
denotes |
Annexin |
T6117 |
8-10 |
NN |
denotes |
A7 |
T6118 |
37-42 |
NNS |
denotes |
cells |
T6119 |
11-16 |
NN |
denotes |
knock |
T6120 |
17-20 |
NN |
denotes |
out |
T6121 |
21-26 |
NN |
denotes |
mouse |
T6122 |
27-30 |
JJ |
denotes |
red |
T6123 |
31-36 |
NN |
denotes |
blood |
T6124 |
43-47 |
VBP |
denotes |
show |
T6125 |
48-49 |
DT |
denotes |
a |
T6126 |
60-65 |
NN |
denotes |
shape |
T6127 |
50-54 |
RBR |
denotes |
more |
T6128 |
55-59 |
JJ |
denotes |
flat |
T6129 |
66-69 |
CC |
denotes |
and |
T6130 |
70-74 |
VBP |
denotes |
have |
T6131 |
75-76 |
DT |
denotes |
a |
T6132 |
92-102 |
NN |
denotes |
resistance |
T6133 |
77-83 |
JJR |
denotes |
higher |
T6134 |
84-91 |
JJ |
denotes |
osmotic |
T6135 |
102-103 |
. |
denotes |
. |
T6136 |
103-271 |
sentence |
denotes |
The presence of annexin A7 may alter the membrane flexibility in that it supports the typical biconcave membrane shape and leads to a lower minimal osmotic resistance. |
T6137 |
104-107 |
DT |
denotes |
The |
T6138 |
108-116 |
NN |
denotes |
presence |
T6139 |
135-140 |
VB |
denotes |
alter |
T6140 |
117-119 |
IN |
denotes |
of |
T6141 |
120-127 |
NN |
denotes |
annexin |
T6142 |
128-130 |
NN |
denotes |
A7 |
T6143 |
131-134 |
MD |
denotes |
may |
T6144 |
141-144 |
DT |
denotes |
the |
T6145 |
154-165 |
NN |
denotes |
flexibility |
T6146 |
145-153 |
NN |
denotes |
membrane |
T6147 |
166-168 |
IN |
denotes |
in |
T6148 |
177-185 |
VBZ |
denotes |
supports |
T6149 |
169-173 |
IN |
denotes |
that |
T6150 |
174-176 |
PRP |
denotes |
it |
T6151 |
186-189 |
DT |
denotes |
the |
T6152 |
217-222 |
NN |
denotes |
shape |
T6153 |
190-197 |
JJ |
denotes |
typical |
T6154 |
198-207 |
NN |
denotes |
biconcave |
T6155 |
208-216 |
NN |
denotes |
membrane |
T6156 |
223-226 |
CC |
denotes |
and |
T6157 |
227-232 |
VBZ |
denotes |
leads |
T6158 |
233-235 |
IN |
denotes |
to |
T6159 |
236-237 |
DT |
denotes |
a |
T6160 |
260-270 |
NN |
denotes |
resistance |
T6161 |
238-243 |
JJR |
denotes |
lower |
T6162 |
244-251 |
JJ |
denotes |
minimal |
T6163 |
252-259 |
JJ |
denotes |
osmotic |
T6164 |
270-271 |
. |
denotes |
. |
T6165 |
271-411 |
sentence |
denotes |
Annexin A7 does not appear to have an influence on plasma membrane integrity itself as the maximal osmotic resistance value stays constant. |
T6166 |
272-279 |
NN |
denotes |
Annexin |
T6167 |
280-282 |
NN |
denotes |
A7 |
T6168 |
292-298 |
VB |
denotes |
appear |
T6169 |
283-287 |
VBZ |
denotes |
does |
T6170 |
288-291 |
RB |
denotes |
not |
T6171 |
299-301 |
TO |
denotes |
to |
T6172 |
302-306 |
VB |
denotes |
have |
T6173 |
307-309 |
DT |
denotes |
an |
T6174 |
310-319 |
NN |
denotes |
influence |
T6175 |
320-322 |
IN |
denotes |
on |
T6176 |
323-329 |
NN |
denotes |
plasma |
T6177 |
330-338 |
NN |
denotes |
membrane |
T6178 |
339-348 |
NN |
denotes |
integrity |
T6179 |
349-355 |
PRP |
denotes |
itself |
T6180 |
356-358 |
IN |
denotes |
as |
T6181 |
396-401 |
VBZ |
denotes |
stays |
T6182 |
359-362 |
DT |
denotes |
the |
T6183 |
390-395 |
NN |
denotes |
value |
T6184 |
363-370 |
JJ |
denotes |
maximal |
T6185 |
371-378 |
JJ |
denotes |
osmotic |
T6186 |
379-389 |
NN |
denotes |
resistance |
T6187 |
402-410 |
JJ |
denotes |
constant |
T6188 |
410-411 |
. |
denotes |
. |
T6189 |
411-532 |
sentence |
denotes |
Ca2+ and membrane skeletal proteins are known to play key roles on the red blood cell membrane shape and stability [47]. |
T6190 |
412-416 |
NN |
denotes |
Ca2+ |
T6191 |
439-447 |
NN |
denotes |
proteins |
T6192 |
417-420 |
CC |
denotes |
and |
T6193 |
421-429 |
NN |
denotes |
membrane |
T6194 |
430-438 |
JJ |
denotes |
skeletal |
T6195 |
452-457 |
VBN |
denotes |
known |
T6196 |
448-451 |
VBP |
denotes |
are |
T6197 |
458-460 |
TO |
denotes |
to |
T6198 |
461-465 |
VB |
denotes |
play |
T6199 |
466-469 |
JJ |
denotes |
key |
T6200 |
470-475 |
NNS |
denotes |
roles |
T6201 |
476-478 |
IN |
denotes |
on |
T6202 |
479-482 |
DT |
denotes |
the |
T6203 |
507-512 |
NN |
denotes |
shape |
T6204 |
483-486 |
JJ |
denotes |
red |
T6205 |
493-497 |
NN |
denotes |
cell |
T6206 |
487-492 |
NN |
denotes |
blood |
T6207 |
498-506 |
NN |
denotes |
membrane |
T6208 |
513-516 |
CC |
denotes |
and |
T6209 |
517-526 |
NN |
denotes |
stability |
T6210 |
527-528 |
-LRB- |
denotes |
[ |
T6211 |
528-530 |
CD |
denotes |
47 |
T6212 |
530-531 |
-RRB- |
denotes |
] |
T6213 |
531-532 |
. |
denotes |
. |
T6214 |
532-647 |
sentence |
denotes |
Annexins have been reported to bind directly to F-actin, we could however exclude such an activity for annexin A7. |
T6215 |
533-541 |
NNS |
denotes |
Annexins |
T6216 |
552-560 |
VBN |
denotes |
reported |
T6217 |
542-546 |
VBP |
denotes |
have |
T6218 |
547-551 |
VBN |
denotes |
been |
T6219 |
607-614 |
VB |
denotes |
exclude |
T6220 |
561-563 |
TO |
denotes |
to |
T6221 |
564-568 |
VB |
denotes |
bind |
T6222 |
569-577 |
RB |
denotes |
directly |
T6223 |
578-580 |
IN |
denotes |
to |
T6224 |
581-582 |
NN |
denotes |
F |
T6225 |
583-588 |
NN |
denotes |
actin |
T6226 |
582-583 |
HYPH |
denotes |
- |
T6227 |
588-590 |
, |
denotes |
, |
T6228 |
590-592 |
PRP |
denotes |
we |
T6229 |
593-598 |
MD |
denotes |
could |
T6230 |
599-606 |
RB |
denotes |
however |
T6231 |
615-619 |
JJ |
denotes |
such |
T6232 |
623-631 |
NN |
denotes |
activity |
T6233 |
620-622 |
DT |
denotes |
an |
T6234 |
632-635 |
IN |
denotes |
for |
T6235 |
636-643 |
NN |
denotes |
annexin |
T6236 |
644-646 |
NN |
denotes |
A7 |
T6237 |
646-647 |
. |
denotes |
. |
T6238 |
647-908 |
sentence |
denotes |
Nevertheless it might interact with other components and have a role in organizing the membrane cytoskeleton, controlling raft protein associations or influencing the ionic strength of red blood cells on its own or by interfering with other signaling pathways. |
T6239 |
648-660 |
RB |
denotes |
Nevertheless |
T6240 |
670-678 |
VB |
denotes |
interact |
T6241 |
661-663 |
PRP |
denotes |
it |
T6242 |
664-669 |
MD |
denotes |
might |
T6243 |
679-683 |
IN |
denotes |
with |
T6244 |
684-689 |
JJ |
denotes |
other |
T6245 |
690-700 |
NNS |
denotes |
components |
T6246 |
701-704 |
CC |
denotes |
and |
T6247 |
705-709 |
VBP |
denotes |
have |
T6248 |
710-711 |
DT |
denotes |
a |
T6249 |
712-716 |
NN |
denotes |
role |
T6250 |
717-719 |
IN |
denotes |
in |
T6251 |
720-730 |
VBG |
denotes |
organizing |
T6252 |
731-734 |
DT |
denotes |
the |
T6253 |
744-756 |
NN |
denotes |
cytoskeleton |
T6254 |
735-743 |
NN |
denotes |
membrane |
T6255 |
756-758 |
, |
denotes |
, |
T6256 |
758-769 |
VBG |
denotes |
controlling |
T6257 |
770-774 |
NN |
denotes |
raft |
T6258 |
775-782 |
NN |
denotes |
protein |
T6259 |
783-795 |
NNS |
denotes |
associations |
T6260 |
796-798 |
CC |
denotes |
or |
T6261 |
799-810 |
VBG |
denotes |
influencing |
T6262 |
811-814 |
DT |
denotes |
the |
T6263 |
821-829 |
NN |
denotes |
strength |
T6264 |
815-820 |
JJ |
denotes |
ionic |
T6265 |
830-832 |
IN |
denotes |
of |
T6266 |
833-836 |
JJ |
denotes |
red |
T6267 |
843-848 |
NNS |
denotes |
cells |
T6268 |
837-842 |
NN |
denotes |
blood |
T6269 |
849-851 |
IN |
denotes |
on |
T6270 |
852-855 |
PRP$ |
denotes |
its |
T6271 |
856-859 |
JJ |
denotes |
own |
T6272 |
860-862 |
CC |
denotes |
or |
T6273 |
863-865 |
IN |
denotes |
by |
T6274 |
866-877 |
VBG |
denotes |
interfering |
T6275 |
878-882 |
IN |
denotes |
with |
T6276 |
883-888 |
JJ |
denotes |
other |
T6277 |
899-907 |
NNS |
denotes |
pathways |
T6278 |
889-898 |
NN |
denotes |
signaling |
T6279 |
907-908 |
. |
denotes |
. |
R3592 |
T6132 |
T6130 |
dobj |
resistance,have |
R3596 |
T6133 |
T6132 |
amod |
higher,resistance |
R3598 |
T6134 |
T6132 |
amod |
osmotic,resistance |
R3599 |
T6135 |
T6124 |
punct |
.,show |
R3601 |
T6137 |
T6138 |
det |
The,presence |
R3603 |
T6138 |
T6139 |
nsubj |
presence,alter |
R3604 |
T6140 |
T6138 |
prep |
of,presence |
R3606 |
T6141 |
T6142 |
compound |
annexin,A7 |
R3607 |
T6142 |
T6140 |
pobj |
A7,of |
R3608 |
T6143 |
T6139 |
aux |
may,alter |
R3610 |
T6144 |
T6145 |
det |
the,flexibility |
R3611 |
T6145 |
T6139 |
dobj |
flexibility,alter |
R3613 |
T6146 |
T6145 |
compound |
membrane,flexibility |
R3614 |
T6147 |
T6148 |
mark |
in,supports |
R3615 |
T6148 |
T6139 |
advcl |
supports,alter |
R3617 |
T6149 |
T6148 |
mark |
that,supports |
R3618 |
T6150 |
T6148 |
nsubj |
it,supports |
R3620 |
T6151 |
T6152 |
det |
the,shape |
R3621 |
T6152 |
T6148 |
dobj |
shape,supports |
R3622 |
T6153 |
T6152 |
amod |
typical,shape |
R3624 |
T6154 |
T6152 |
compound |
biconcave,shape |
R3625 |
T6155 |
T6152 |
compound |
membrane,shape |
R3627 |
T6156 |
T6148 |
cc |
and,supports |
R3628 |
T6157 |
T6148 |
conj |
leads,supports |
R3629 |
T6158 |
T6157 |
prep |
to,leads |
R3630 |
T6159 |
T6160 |
det |
a,resistance |
R3632 |
T6160 |
T6158 |
pobj |
resistance,to |
R3633 |
T6161 |
T6160 |
amod |
lower,resistance |
R3634 |
T6162 |
T6160 |
amod |
minimal,resistance |
R3635 |
T6163 |
T6160 |
amod |
osmotic,resistance |
R3637 |
T6164 |
T6139 |
punct |
.,alter |
R3638 |
T6166 |
T6167 |
compound |
Annexin,A7 |
R3639 |
T6167 |
T6168 |
nsubj |
A7,appear |
R3641 |
T6169 |
T6168 |
aux |
does,appear |
R3642 |
T6170 |
T6168 |
neg |
not,appear |
R3644 |
T6171 |
T6172 |
aux |
to,have |
R3645 |
T6172 |
T6168 |
xcomp |
have,appear |
R3646 |
T6173 |
T6174 |
det |
an,influence |
R3648 |
T6174 |
T6172 |
dobj |
influence,have |
R3649 |
T6175 |
T6174 |
prep |
on,influence |
R3651 |
T6176 |
T6177 |
compound |
plasma,membrane |
R3652 |
T6177 |
T6178 |
compound |
membrane,integrity |
R3653 |
T6178 |
T6175 |
pobj |
integrity,on |
R3654 |
T6116 |
T6117 |
nmod |
Annexin,A7 |
R3655 |
T6179 |
T6178 |
appos |
itself,integrity |
R3656 |
T6180 |
T6181 |
mark |
as,stays |
R3657 |
T6181 |
T6172 |
advcl |
stays,have |
R3658 |
T6182 |
T6183 |
det |
the,value |
R3659 |
T6117 |
T6118 |
nmod |
A7,cells |
R3660 |
T6183 |
T6181 |
nsubj |
value,stays |
R3661 |
T6184 |
T6183 |
amod |
maximal,value |
R3662 |
T6185 |
T6186 |
amod |
osmotic,resistance |
R3663 |
T6118 |
T6124 |
nsubj |
cells,show |
R3664 |
T6186 |
T6183 |
compound |
resistance,value |
R3665 |
T6187 |
T6181 |
acomp |
constant,stays |
R3666 |
T6188 |
T6168 |
punct |
.,appear |
R3667 |
T6119 |
T6120 |
nmod |
knock,out |
R3668 |
T6190 |
T6191 |
nmod |
Ca2+,proteins |
R3669 |
T6120 |
T6121 |
nmod |
out,mouse |
R3670 |
T6191 |
T6195 |
nsubjpass |
proteins,known |
R3671 |
T6192 |
T6190 |
cc |
and,Ca2+ |
R3672 |
T6193 |
T6194 |
npadvmod |
membrane,skeletal |
R3673 |
T6121 |
T6118 |
nmod |
mouse,cells |
R3674 |
T6194 |
T6190 |
conj |
skeletal,Ca2+ |
R3675 |
T6122 |
T6118 |
amod |
red,cells |
R3676 |
T6196 |
T6195 |
auxpass |
are,known |
R3677 |
T6197 |
T6198 |
aux |
to,play |
R3678 |
T6198 |
T6195 |
xcomp |
play,known |
R3679 |
T6123 |
T6118 |
compound |
blood,cells |
R3680 |
T6199 |
T6200 |
amod |
key,roles |
R3681 |
T6200 |
T6198 |
dobj |
roles,play |
R3682 |
T6125 |
T6126 |
det |
a,shape |
R3683 |
T6201 |
T6198 |
prep |
on,play |
R3684 |
T6202 |
T6203 |
det |
the,shape |
R3685 |
T6203 |
T6201 |
pobj |
shape,on |
R3686 |
T6204 |
T6205 |
amod |
red,cell |
R3687 |
T6205 |
T6203 |
compound |
cell,shape |
R3688 |
T6206 |
T6205 |
compound |
blood,cell |
R3689 |
T6126 |
T6124 |
dobj |
shape,show |
R3690 |
T6127 |
T6128 |
advmod |
more,flat |
R3691 |
T6207 |
T6203 |
compound |
membrane,shape |
R3692 |
T6208 |
T6203 |
cc |
and,shape |
R3693 |
T6209 |
T6203 |
conj |
stability,shape |
R3694 |
T6128 |
T6126 |
amod |
flat,shape |
R3695 |
T6210 |
T6211 |
punct |
[,47 |
R3696 |
T6211 |
T6195 |
parataxis |
47,known |
R3697 |
T6129 |
T6124 |
cc |
and,show |
R3698 |
T6212 |
T6211 |
punct |
],47 |
R3699 |
T6213 |
T6195 |
punct |
.,known |
R3700 |
T6215 |
T6216 |
nsubjpass |
Annexins,reported |
R3701 |
T6130 |
T6124 |
conj |
have,show |
R3702 |
T6216 |
T6219 |
ccomp |
reported,exclude |
R3703 |
T6217 |
T6216 |
aux |
have,reported |
R3704 |
T6131 |
T6132 |
det |
a,resistance |
R3705 |
T6218 |
T6216 |
auxpass |
been,reported |
R3706 |
T6220 |
T6221 |
aux |
to,bind |
R3707 |
T6239 |
T6240 |
advmod |
Nevertheless,interact |
R3708 |
T6221 |
T6216 |
xcomp |
bind,reported |
R3709 |
T6222 |
T6221 |
advmod |
directly,bind |
R3710 |
T6223 |
T6221 |
prep |
to,bind |
R3711 |
T6224 |
T6225 |
compound |
F,actin |
R3712 |
T6225 |
T6223 |
pobj |
actin,to |
R3713 |
T6226 |
T6225 |
punct |
-,actin |
R3714 |
T6241 |
T6240 |
nsubj |
it,interact |
R3715 |
T6227 |
T6219 |
punct |
", ",exclude |
R3716 |
T6228 |
T6219 |
nsubj |
we,exclude |
R3717 |
T6229 |
T6219 |
aux |
could,exclude |
R3718 |
T6230 |
T6219 |
advmod |
however,exclude |
R3719 |
T6242 |
T6240 |
aux |
might,interact |
R3720 |
T6231 |
T6232 |
amod |
such,activity |
R3721 |
T6232 |
T6219 |
dobj |
activity,exclude |
R3722 |
T6243 |
T6240 |
prep |
with,interact |
R3723 |
T6233 |
T6232 |
det |
an,activity |
R3724 |
T6234 |
T6219 |
prep |
for,exclude |
R3725 |
T6244 |
T6245 |
amod |
other,components |
R3726 |
T6235 |
T6236 |
compound |
annexin,A7 |
R3727 |
T6236 |
T6234 |
pobj |
A7,for |
R3728 |
T6237 |
T6219 |
punct |
.,exclude |
R3729 |
T6245 |
T6243 |
pobj |
components,with |
R3730 |
T6246 |
T6240 |
cc |
and,interact |
R3731 |
T6247 |
T6240 |
conj |
have,interact |
R3732 |
T6248 |
T6249 |
det |
a,role |
R3733 |
T6249 |
T6247 |
dobj |
role,have |
R3735 |
T6250 |
T6247 |
prep |
in,have |
R3742 |
T6251 |
T6250 |
pcomp |
organizing,in |
R3744 |
T6252 |
T6253 |
det |
the,cytoskeleton |
R3748 |
T6253 |
T6251 |
dobj |
cytoskeleton,organizing |
R3751 |
T6254 |
T6253 |
compound |
membrane,cytoskeleton |
R3755 |
T6255 |
T6240 |
punct |
", ",interact |
R3758 |
T6256 |
T6240 |
advcl |
controlling,interact |
R3762 |
T6257 |
T6258 |
compound |
raft,protein |
R3766 |
T6258 |
T6259 |
compound |
protein,associations |
R3769 |
T6259 |
T6256 |
dobj |
associations,controlling |
R3771 |
T6260 |
T6256 |
cc |
or,controlling |
R3775 |
T6261 |
T6256 |
conj |
influencing,controlling |
R3780 |
T6262 |
T6263 |
det |
the,strength |
R3783 |
T6263 |
T6261 |
dobj |
strength,influencing |
R3787 |
T6264 |
T6263 |
amod |
ionic,strength |
R3793 |
T6265 |
T6263 |
prep |
of,strength |
R3795 |
T6266 |
T6267 |
amod |
red,cells |
R3799 |
T6267 |
T6265 |
pobj |
cells,of |
R3800 |
T6268 |
T6267 |
compound |
blood,cells |
R3802 |
T6269 |
T6256 |
prep |
on,controlling |
R3804 |
T6270 |
T6271 |
poss |
its,own |
R3809 |
T6271 |
T6269 |
pobj |
own,on |
R3813 |
T6272 |
T6269 |
cc |
or,on |
R3815 |
T6273 |
T6269 |
conj |
by,on |
R3818 |
T6274 |
T6273 |
pcomp |
interfering,by |
R3822 |
T6275 |
T6274 |
prep |
with,interfering |
R3826 |
T6276 |
T6277 |
amod |
other,pathways |
R3829 |
T6277 |
T6275 |
pobj |
pathways,with |
R3834 |
T6278 |
T6277 |
compound |
signaling,pathways |
R3837 |
T6279 |
T6240 |
punct |
.,interact |