PMC:194730 / 1495-1830
Annnotations
craft-sa-dev
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have demonstrated the presence of both annexin A7 isoforms in red blood cells and the presence of the small isoform in platelets. In both cell types the loss of annexin A7 impairs cellular functions. The defects observed are however not compatible with a crucial role for annexin A7 in membrane fusion processes in these cell types."}
craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T118","span":{"begin":42,"end":52},"obj":"PR:000004080"},{"id":"T119","span":{"begin":53,"end":61},"obj":"SO:0001060"},{"id":"T120","span":{"begin":65,"end":80},"obj":"CL:0000232"},{"id":"T121","span":{"begin":69,"end":74},"obj":"UBERON:0000178"},{"id":"T122","span":{"begin":111,"end":118},"obj":"SO:0001060"},{"id":"T123","span":{"begin":122,"end":131},"obj":"CL:0000233"},{"id":"T124","span":{"begin":164,"end":174},"obj":"PR:000004080"},{"id":"T125","span":{"begin":275,"end":285},"obj":"PR:000004080"},{"id":"T126","span":{"begin":289,"end":297},"obj":"GO:0016020"},{"id":"T127","span":{"begin":289,"end":304},"obj":"GO:0061025"}],"text":"We have demonstrated the presence of both annexin A7 isoforms in red blood cells and the presence of the small isoform in platelets. In both cell types the loss of annexin A7 impairs cellular functions. The defects observed are however not compatible with a crucial role for annexin A7 in membrane fusion processes in these cell types."}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T191","span":{"begin":42,"end":52},"obj":"PR_EXT:000004080"},{"id":"T192","span":{"begin":53,"end":61},"obj":"SO_EXT:0001060"},{"id":"T193","span":{"begin":65,"end":80},"obj":"CL:0000232"},{"id":"T194","span":{"begin":69,"end":74},"obj":"UBERON:0000178"},{"id":"T195","span":{"begin":75,"end":80},"obj":"CL_GO_EXT:cell"},{"id":"T196","span":{"begin":111,"end":118},"obj":"SO_EXT:0001060"},{"id":"T197","span":{"begin":122,"end":131},"obj":"CL:0000233"},{"id":"T198","span":{"begin":141,"end":145},"obj":"CL_GO_EXT:cell"},{"id":"T199","span":{"begin":164,"end":174},"obj":"PR_EXT:000004080"},{"id":"T200","span":{"begin":183,"end":191},"obj":"CL_GO_EXT:cell"},{"id":"T201","span":{"begin":275,"end":285},"obj":"PR_EXT:000004080"},{"id":"T202","span":{"begin":289,"end":297},"obj":"GO:0016020"},{"id":"T203","span":{"begin":289,"end":304},"obj":"GO:0061025"},{"id":"T204","span":{"begin":324,"end":328},"obj":"CL_GO_EXT:cell"}],"text":"We have demonstrated the presence of both annexin A7 isoforms in red blood cells and the presence of the small isoform in platelets. In both cell types the loss of annexin A7 impairs cellular functions. The defects observed are however not compatible with a crucial role for annexin A7 in membrane fusion processes in these cell types."}