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2_test

Id Subject Object Predicate Lexical cue
17349631-16678913-30580538 205-207 16678913 denotes 20
17349631-12505989-30580539 1452-1454 12505989 denotes 32
17349631-16166634-30580539 1452-1454 16166634 denotes 32
17349631-16421204-30580539 1452-1454 16421204 denotes 32
17349631-15145937-30580539 1452-1454 15145937 denotes 32

MyTest

Id Subject Object Predicate Lexical cue
17349631-16678913-30580538 205-207 16678913 denotes 20
17349631-12505989-30580539 1452-1454 12505989 denotes 32
17349631-16166634-30580539 1452-1454 16166634 denotes 32
17349631-16421204-30580539 1452-1454 16421204 denotes 32
17349631-15145937-30580539 1452-1454 15145937 denotes 32

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T3837 14-27 NN denotes proliferation
T3838 28-31 CC denotes and
T3839 32-40 NN denotes survival
T3840 41-43 IN denotes in
T3841 44-48 NN denotes DT40
T3842 49-50 NN denotes B
T3843 51-56 NN denotes cells
T3844 57-64 VB denotes lacking
T3845 65-75 NN denotes expression
T3846 76-78 IN denotes of
T3847 79-82 NN denotes PKD
T3848 83-89 NN denotes family
T3849 90-97 NN denotes kinases
T3850 98-101 NN denotes PKD
T3851 102-109 NN denotes enzymes
T3852 110-114 VB denotes have
T3853 115-125 RB denotes previously
T3854 126-130 VB denotes been
T3855 131-137 VB denotes linked
T3856 138-140 TO denotes to
T3857 141-144 DT denotes the
T3858 145-155 NN denotes regulation
T3859 156-158 IN denotes of
T3860 159-163 NN denotes cell
T3861 164-177 NN denotes proliferation
T3862 178-181 CC denotes and
T3863 182-190 NN denotes survival
T3864 191-192 -LRB- denotes (
T3865 192-200 VB denotes reviewed
T3866 201-203 IN denotes in
T3867 204-205 -LRB- denotes [
T3868 205-207 CD denotes 20
T3869 207-208 -RRB- denotes ]
T3870 208-209 -RRB- denotes )
T3871 211-213 TO denotes To
T3872 214-225 VB denotes investigate
T3873 226-229 DT denotes the
T3874 230-236 NN denotes effect
T3875 237-241 IN denotes that
T3876 242-246 NN denotes loss
T3877 247-249 IN denotes of
T3878 250-253 NN denotes PKD
T3879 254-261 NN denotes kinases
T3880 262-265 VB denotes had
T3881 266-268 IN denotes on
T3882 269-270 NN denotes B
T3883 271-275 NN denotes cell
T3884 276-284 NN denotes survival
T3885 285-291 CC denotes and/or
T3886 292-305 NN denotes proliferation
T3887 306-308 PRP denotes we
T3888 309-317 VB denotes cultured
T3889 318-327 JJ denotes wild-type
T3890 328-331 CC denotes and
T3891 332-340 JJ denotes PKD-null
T3892 341-346 NN denotes cells
T3893 347-349 IN denotes in
T3894 350-353 DT denotes the
T3895 354-362 NN denotes presence
T3896 363-364 -LRB- denotes (
T3897 364-373 NN denotes PKD1/3−/−
T3898 373-374 -COLON- denotes :
T3899 375-387 NN denotes Flag-PKD3+ve
T3900 387-388 -RRB- denotes )
T3901 389-391 CC denotes or
T3902 392-399 NN denotes absence
T3903 400-401 -LRB- denotes (
T3904 401-410 NN denotes PKD1/3−/−
T3905 410-411 -RRB- denotes )
T3906 412-414 IN denotes of
T3907 415-426 NN denotes doxycycline
T3908 427-430 CC denotes and
T3909 431-440 VB denotes monitored
T3910 441-452 JJ denotes exponential
T3911 453-459 NN denotes growth
T3912 461-463 IN denotes As
T3913 464-469 VB denotes shown
T3914 470-472 IN denotes in
T3915 473-477 NNP denotes Fig.
T3916 478-480 NN denotes 2A
T3917 480-481 -COMMA- denotes ,
T3918 482-491 NN denotes PKD1/3−/−
T3919 492-497 NN denotes cells
T3920 498-510 VB denotes proliferated
T3921 511-524 RB denotes exponentially
T3922 525-528 CC denotes and
T3923 529-542 NN denotes re-expression
T3924 543-545 IN denotes of
T3925 546-555 NN denotes Flag-PKD3
T3926 556-558 IN denotes in
T3927 559-564 DT denotes these
T3928 565-570 NN denotes cells
T3929 571-574 VB denotes had
T3930 575-577 DT denotes no
T3931 578-584 NN denotes impact
T3932 585-587 IN denotes on
T3933 588-591 DT denotes the
T3934 592-596 NN denotes rate
T3935 597-599 IN denotes of
T3936 600-613 NN denotes proliferation
T3937 615-626 RB denotes Furthermore
T3938 626-627 -COMMA- denotes ,
T3939 628-631 DT denotes the
T3940 632-641 NN denotes viability
T3941 642-644 IN denotes of
T3942 645-654 NN denotes PKD1/3−/−
T3943 655-656 NN denotes B
T3944 657-662 NN denotes cells
T3945 663-669 IN denotes during
T3946 670-677 JJ denotes routine
T3947 678-687 NN denotes culturing
T3948 688-691 VB denotes was
T3949 692-695 RB denotes not
T3950 696-709 RB denotes significantly
T3951 710-719 JJ denotes different
T3952 720-724 IN denotes from
T3953 725-729 DT denotes that
T3954 730-732 IN denotes of
T3955 733-742 JJ denotes wild-type
T3956 743-744 NN denotes B
T3957 745-750 NN denotes cells
T3958 751-752 -LRB- denotes (
T3959 752-756 NN denotes data
T3960 757-760 RB denotes not
T3961 761-766 VB denotes shown
T3962 766-767 -RRB- denotes )
T3963 769-771 PRP denotes It
T3964 772-775 VB denotes was
T3965 776-781 VB denotes noted
T3966 782-786 IN denotes that
T3967 787-790 DT denotes the
T3968 791-801 NN denotes population
T3969 802-810 NN denotes doubling
T3970 811-815 NN denotes time
T3971 816-818 IN denotes of
T3972 819-828 NN denotes PKD1/3−/−
T3973 829-834 NN denotes cells
T3974 835-838 VB denotes was
T3975 839-847 RB denotes slightly
T3976 848-854 JJ denotes slower
T3977 855-859 IN denotes than
T3978 860-864 DT denotes that
T3979 865-867 IN denotes of
T3980 868-872 JJ denotes wild
T3981 873-877 NN denotes type
T3982 878-882 NN denotes DT40
T3983 883-888 NN denotes cells
T3984 889-890 -LRB- denotes (
T3985 890-902 CD denotes 12.7 ± 2.8 h
T3986 903-909 IN denotes versus
T3987 910-922 CD denotes 10.2 ± 0.4 h
T3988 922-923 -RRB- denotes )
T3989 924-927 CC denotes but
T3990 928-931 DT denotes the
T3991 932-939 NN denotes failure
T3992 940-942 IN denotes of
T3993 943-947 NN denotes PKD3
T3994 948-961 NN denotes re-expression
T3995 962-964 TO denotes to
T3996 965-971 VB denotes modify
T3997 972-975 DT denotes the
T3998 976-989 NN denotes proliferation
T3999 990-994 NN denotes rate
T4000 995-997 IN denotes of
T4001 998-1007 NN denotes PKD1/3−/−
T4002 1008-1013 NN denotes cells
T4003 1014-1022 VB denotes suggests
T4004 1023-1027 IN denotes that
T4005 1028-1033 DT denotes these
T4006 1034-1039 JJ denotes small
T4007 1040-1051 NN denotes differences
T4008 1052-1056 VB denotes were
T4009 1057-1061 RB denotes most
T4010 1062-1068 RB denotes likely
T4011 1069-1072 DT denotes the
T4012 1073-1079 NN denotes result
T4013 1080-1082 IN denotes of
T4014 1083-1089 JJ denotes clonal
T4015 1090-1099 NN denotes variation
T4016 1100-1103 CC denotes and
T4017 1104-1108 VB denotes were
T4018 1109-1112 RB denotes not
T4019 1113-1119 VB denotes caused
T4020 1120-1132 RB denotes specifically
T4021 1133-1135 IN denotes by
T4022 1136-1140 NN denotes loss
T4023 1141-1143 IN denotes of
T4024 1144-1147 NN denotes PKD
T4025 1148-1155 NN denotes enzymes
T4026 1157-1161 RB denotes Thus
T4027 1161-1162 -COMMA- denotes ,
T4028 1163-1166 NN denotes PKD
T4029 1167-1173 NN denotes family
T4030 1174-1181 NN denotes enzymes
T4031 1182-1185 VB denotes are
T4032 1186-1189 RB denotes not
T4033 1190-1199 JJ denotes essential
T4034 1200-1203 IN denotes for
T4035 1204-1214 VB denotes regulating
T4036 1215-1220 JJ denotes basal
T4037 1221-1229 NN denotes survival
T4038 1230-1233 CC denotes and
T4039 1234-1247 NN denotes proliferation
T4040 1248-1250 IN denotes of
T4041 1251-1255 NN denotes DT40
T4042 1256-1257 NN denotes B
T4043 1258-1263 NN denotes cells
T4044 1265-1268 NN denotes PKD
T4045 1269-1276 NN denotes enzymes
T4046 1276-1277 -COMMA- denotes ,
T4047 1278-1290 RB denotes specifically
T4048 1291-1295 NN denotes PKD1
T4049 1296-1299 CC denotes and
T4050 1300-1304 NN denotes PKD2
T4051 1304-1305 -COMMA- denotes ,
T4052 1306-1310 VB denotes have
T4053 1311-1321 RB denotes previously
T4054 1322-1326 VB denotes been
T4055 1327-1333 VB denotes linked
T4056 1334-1336 TO denotes to
T4057 1337-1338 DT denotes a
T4058 1339-1349 JJ denotes protective
T4059 1350-1354 NN denotes role
T4060 1355-1362 IN denotes against
T4061 1363-1372 JJ denotes oxidative
T4062 1373-1387 JJ denotes stress-induced
T4063 1388-1394 NN denotes injury
T4064 1395-1397 IN denotes in
T4065 1398-1401 NN denotes 3T3
T4066 1402-1412 NN denotes fibroblast
T4067 1412-1413 -COMMA- denotes ,
T4068 1414-1418 NN denotes HeLa
T4069 1419-1422 CC denotes and
T4070 1423-1433 JJ denotes epithelial
T4071 1434-1438 NN denotes cell
T4072 1439-1444 NN denotes lines
T4073 1445-1446 -LRB- denotes [
T4074 1446-1454 CD denotes 17,30–32
T4075 1454-1455 -RRB- denotes ]
T4076 1457-1459 PRP denotes We
T4077 1460-1469 RB denotes therefore
T4078 1470-1479 VB denotes addressed
T4079 1480-1483 DT denotes the
T4080 1484-1488 NN denotes role
T4081 1489-1491 IN denotes of
T4082 1492-1495 NN denotes PKD
T4083 1496-1502 NN denotes family
T4084 1503-1510 NN denotes kinases
T4085 1511-1513 IN denotes in
T4086 1514-1524 VB denotes regulating
T4087 1525-1526 NN denotes B
T4088 1527-1531 NN denotes cell
T4089 1532-1540 NN denotes survival
T4090 1541-1543 IN denotes in
T4091 1544-1552 NN denotes response
T4092 1553-1555 TO denotes to
T4093 1556-1565 JJ denotes oxidative
T4094 1566-1572 NN denotes stress
T4095 1573-1576 CC denotes and
T4096 1577-1582 JJ denotes other
T4097 1583-1589 NN denotes stress
T4098 1590-1597 NN denotes stimuli
T4099 1599-1601 IN denotes As
T4100 1602-1607 VB denotes shown
T4101 1608-1610 IN denotes in
T4102 1611-1615 NNP denotes Fig.
T4103 1616-1618 NN denotes 2B
T4104 1618-1619 -COMMA- denotes ,
T4105 1620-1624 NN denotes loss
T4106 1625-1627 IN denotes of
T4107 1628-1634 NN denotes PKD1/3
T4108 1635-1645 NN denotes expression
T4109 1646-1649 VB denotes had
T4110 1650-1652 DT denotes no
T4111 1653-1664 JJ denotes significant
T4112 1665-1671 NN denotes impact
T4113 1672-1674 IN denotes on
T4114 1675-1678 DT denotes the
T4115 1679-1687 NN denotes survival
T4116 1688-1690 IN denotes of
T4117 1691-1695 NN denotes DT40
T4118 1696-1697 NN denotes B
T4119 1698-1703 NN denotes cells
T4120 1704-1706 IN denotes in
T4121 1707-1715 NN denotes response
T4122 1716-1718 TO denotes to
T4123 1719-1732 JJ denotes mitochondrial
T4124 1733-1739 NN denotes stress
T4125 1740-1747 NN denotes stimuli
T4126 1748-1749 -LRB- denotes (
T4127 1749-1753 NN denotes H2O2
T4128 1754-1756 CC denotes or
T4129 1757-1762 NN denotes serum
T4130 1763-1774 NN denotes deprivation
T4131 1774-1775 -RRB- denotes )
T4132 1775-1776 -COLON- denotes ;
T4133 1777-1780 NN denotes DNA
T4134 1781-1789 NN denotes damaging
T4135 1790-1796 NN denotes agents
T4136 1797-1798 -LRB- denotes (
T4137 1798-1807 NN denotes etoposide
T4138 1808-1810 CC denotes or
T4139 1811-1822 NN denotes doxorubicin
T4140 1822-1823 -RRB- denotes )
T4141 1823-1824 -COLON- denotes ;
T4142 1825-1827 NN denotes ER
T4143 1828-1835 NN denotes pathway
T4144 1836-1842 NN denotes stress
T4145 1843-1846 IN denotes due
T4146 1847-1849 TO denotes to
T4147 1850-1857 NN denotes calcium
T4148 1858-1866 NN denotes overload
T4149 1867-1868 -LRB- denotes (
T4150 1868-1880 NN denotes thapsigargin
T4151 1880-1881 -RRB- denotes )
T4152 1882-1884 CC denotes or
T4153 1885-1894 VB denotes following
T4154 1895-1904 VB denotes prolonged
T4155 1905-1914 NN denotes treatment
T4156 1915-1919 IN denotes with
T4157 1920-1927 NN denotes phorbol
T4158 1928-1934 NN denotes esters
T4159 1935-1937 CC denotes or
T4160 1938-1950 NN denotes Trichostatin
T4161 1951-1952 NN denotes A
T4162 1952-1953 -COMMA- denotes ,
T4163 1954-1956 DT denotes an
T4164 1957-1966 NN denotes inhibitor
T4165 1967-1969 IN denotes of
T4166 1970-1975 NN denotes class
T4167 1976-1980 NN denotes I/II
T4168 1981-1986 NN denotes HDACs
T4169 1988-1992 RB denotes Thus
T4170 1992-1993 -COMMA- denotes ,
T4171 1994-1997 NN denotes PKD
T4172 1998-2005 NN denotes kinases
T4173 2006-2008 VB denotes do
T4174 2009-2012 RB denotes not
T4175 2013-2017 VB denotes play
T4176 2018-2020 DT denotes an
T4177 2021-2030 JJ denotes essential
T4178 2031-2035 NN denotes role
T4179 2036-2038 IN denotes in
T4180 2039-2049 VB denotes regulating
T4181 2050-2051 NN denotes B
T4182 2052-2056 NN denotes cell
T4183 2057-2065 NN denotes survival
T4184 2066-2068 IN denotes in
T4185 2069-2077 NN denotes response
T4186 2078-2080 TO denotes to
T4187 2081-2082 DT denotes a
T4188 2083-2088 NN denotes range
T4189 2089-2091 IN denotes of
T4190 2092-2101 JJ denotes different
T4191 2102-2108 NN denotes stress
T4192 2109-2116 NN denotes stimuli
R3056 T3837 T3838 arg1Of proliferation,and
R3058 T3838 T3840 arg1Of and,in
R3059 T3839 T3838 arg2Of survival,and
R3060 T3843 T3840 arg2Of cells,in
R3061 T3843 T3841 arg1Of cells,DT40
R3062 T3843 T3842 arg1Of cells,B
R3063 T3843 T3844 arg1Of cells,lacking
R3064 T3845 T3844 arg2Of expression,lacking
R3065 T3845 T3846 arg1Of expression,of
R3066 T3849 T3846 arg2Of kinases,of
R3067 T3849 T3847 arg1Of kinases,PKD
R3068 T3849 T3848 arg1Of kinases,family
R3069 T3851 T3850 arg1Of enzymes,PKD
R3070 T3851 T3852 arg1Of enzymes,have
R3071 T3851 T3854 arg1Of enzymes,been
R3072 T3851 T3855 arg2Of enzymes,linked
R3073 T3855 T3852 arg2Of linked,have
R3074 T3855 T3853 arg1Of linked,previously
R3075 T3855 T3854 arg2Of linked,been
R3076 T3855 T3856 arg1Of linked,to
R3077 T3858 T3856 arg2Of regulation,to
R3078 T3858 T3857 arg1Of regulation,the
R3079 T3858 T3859 arg1Of regulation,of
R3080 T3861 T3862 arg1Of proliferation,and
R3081 T3862 T3859 arg2Of and,of
R3082 T3862 T3860 arg1Of and,cell
R3083 T3862 T3864 arg1Of and,(
R3084 T3863 T3862 arg2Of survival,and
R3085 T3865 T3864 arg2Of reviewed,(
R3086 T3865 T3866 arg1Of reviewed,in
R3087 T3865 T3867 arg1Of reviewed,[
R3088 T3868 T3867 arg2Of 20,[
R3089 T3869 T3867 arg3Of ],[
R3090 T3870 T3864 arg3Of ),(
R3091 T3872 T3871 arg1Of investigate,To
R3092 T3874 T3872 arg2Of effect,investigate
R3093 T3874 T3873 arg1Of effect,the
R3094 T3876 T3877 arg1Of loss,of
R3095 T3876 T3880 arg1Of loss,had
R3096 T3879 T3877 arg2Of kinases,of
R3097 T3879 T3878 arg1Of kinases,PKD
R3098 T3880 T3874 arg2Of had,effect
R3099 T3880 T3875 arg1Of had,that
R3100 T3880 T3881 arg1Of had,on
R3101 T3884 T3885 arg1Of survival,and/or
R3102 T3885 T3881 arg2Of and/or,on
R3103 T3885 T3882 arg1Of and/or,B
R3104 T3885 T3883 arg1Of and/or,cell
R3105 T3886 T3885 arg2Of proliferation,and/or
R3106 T3887 T3872 arg1Of we,investigate
R3107 T3887 T3888 arg1Of we,cultured
R3108 T3888 T3871 modOf cultured,To
R3109 T3888 T3893 arg1Of cultured,in
R3110 T3889 T3890 arg1Of wild-type,and
R3111 T3891 T3890 arg2Of PKD-null,and
R3112 T3892 T3888 arg2Of cells,cultured
R3113 T3892 T3889 arg1Of cells,wild-type
R3114 T3892 T3891 arg1Of cells,PKD-null
R3115 T3895 T3893 arg2Of presence,in
R3116 T3895 T3894 arg1Of presence,the
R3117 T3895 T3896 arg1Of presence,(
R3118 T3897 T3896 arg2Of PKD1/3−/−,(
R3119 T3898 T3896 arg3Of :,(
R3120 T3899 T3900 arg1Of Flag-PKD3+ve,)
R3121 T3899 T3901 arg1Of Flag-PKD3+ve,or
R3122 T3901 T3909 arg1Of or,monitored
R3123 T3902 T3901 arg2Of absence,or
R3124 T3902 T3903 arg1Of absence,(
R3125 T3902 T3906 arg1Of absence,of
R3126 T3904 T3903 arg2Of PKD1/3−/−,(
R3127 T3905 T3903 arg3Of ),(
R3128 T3907 T3906 arg2Of doxycycline,of
R3129 T3909 T3908 arg1Of monitored,and
R3130 T3911 T3909 arg2Of growth,monitored
R3131 T3911 T3910 arg1Of growth,exponential
R3132 T3913 T3912 arg2Of shown,As
R3133 T3913 T3914 arg1Of shown,in
R3134 T3916 T3914 arg2Of 2A,in
R3135 T3916 T3915 arg1Of 2A,Fig.
R3136 T3919 T3918 arg1Of cells,PKD1/3−/−
R3137 T3919 T3920 arg1Of cells,proliferated
R3138 T3920 T3921 arg1Of proliferated,exponentially
R3139 T3920 T3922 arg1Of proliferated,and
R3140 T3922 T3912 arg1Of and,As
R3141 T3922 T3917 arg1Of and,","
R3142 T3923 T3924 arg1Of re-expression,of
R3143 T3923 T3926 arg1Of re-expression,in
R3144 T3923 T3929 arg1Of re-expression,had
R3145 T3925 T3924 arg2Of Flag-PKD3,of
R3146 T3928 T3926 arg2Of cells,in
R3147 T3928 T3927 arg1Of cells,these
R3148 T3929 T3922 arg2Of had,and
R3149 T3931 T3929 arg2Of impact,had
R3150 T3931 T3930 arg1Of impact,no
R3151 T3931 T3932 arg1Of impact,on
R3152 T3934 T3932 arg2Of rate,on
R3153 T3934 T3933 arg1Of rate,the
R3154 T3934 T3935 arg1Of rate,of
R3155 T3936 T3935 arg2Of proliferation,of
R3156 T3940 T3939 arg1Of viability,the
R3157 T3940 T3941 arg1Of viability,of
R3158 T3940 T3945 arg1Of viability,during
R3159 T3940 T3948 arg1Of viability,was
R3160 T3940 T3951 arg1Of viability,different
R3161 T3944 T3941 arg2Of cells,of
R3162 T3944 T3942 arg1Of cells,PKD1/3−/−
R3163 T3944 T3943 arg1Of cells,B
R3164 T3947 T3945 arg2Of culturing,during
R3165 T3947 T3946 arg1Of culturing,routine
R3166 T3948 T3937 arg1Of was,Furthermore
R3167 T3948 T3938 arg1Of was,","
R3168 T3948 T3949 arg1Of was,not
R3169 T3951 T3948 arg2Of different,was
R3170 T3951 T3950 arg1Of different,significantly
R3171 T3951 T3952 arg1Of different,from
R3172 T3953 T3952 arg2Of that,from
R3173 T3953 T3954 arg1Of that,of
R3174 T3957 T3954 arg2Of cells,of
R3175 T3957 T3955 arg1Of cells,wild-type
R3176 T3957 T3956 arg1Of cells,B
R3177 T3957 T3958 arg1Of cells,(
R3178 T3959 T3958 arg2Of data,(
R3179 T3959 T3961 arg2Of data,shown
R3180 T3961 T3960 arg1Of shown,not
R3181 T3962 T3958 arg3Of ),(
R3182 T3963 T3964 arg1Of It,was
R3183 T3963 T3965 arg2Of It,noted
R3184 T3965 T3964 arg2Of noted,was
R3185 T3970 T3967 arg1Of time,the
R3186 T3970 T3968 arg1Of time,population
R3187 T3970 T3969 arg1Of time,doubling
R3188 T3970 T3971 arg1Of time,of
R3189 T3970 T3974 arg1Of time,was
R3190 T3970 T3976 arg1Of time,slower
R3191 T3973 T3971 arg2Of cells,of
R3192 T3973 T3972 arg1Of cells,PKD1/3−/−
R3193 T3974 T3989 arg1Of was,but
R3194 T3976 T3974 arg2Of slower,was
R3195 T3976 T3975 arg1Of slower,slightly
R3196 T3976 T3977 arg1Of slower,than
R3197 T3978 T3977 arg2Of that,than
R3198 T3978 T3979 arg1Of that,of
R3199 T3983 T3979 arg2Of cells,of
R3200 T3983 T3980 arg1Of cells,wild
R3201 T3983 T3981 arg1Of cells,type
R3202 T3983 T3982 arg1Of cells,DT40
R3203 T3983 T3984 arg1Of cells,(
R3204 T3985 T3984 arg2Of 12.7 ± 2.8 h,(
R3205 T3985 T3986 arg1Of 12.7 ± 2.8 h,versus
R3206 T3987 T3986 arg2Of 10.2 ± 0.4 h,versus
R3207 T3988 T3984 arg3Of ),(
R3208 T3989 T3965 arg3Of but,noted
R3209 T3989 T3966 arg1Of but,that
R3210 T3991 T3990 arg1Of failure,the
R3211 T3991 T3992 arg1Of failure,of
R3212 T3991 T3995 modOf failure,to
R3213 T3991 T4003 arg1Of failure,suggests
R3214 T3994 T3992 arg2Of re-expression,of
R3215 T3994 T3993 arg1Of re-expression,PKD3
R3216 T3996 T3995 arg1Of modify,to
R3217 T3999 T3996 arg2Of rate,modify
R3218 T3999 T3997 arg1Of rate,the
R3219 T3999 T3998 arg1Of rate,proliferation
R3220 T3999 T4000 arg1Of rate,of
R3221 T4002 T4000 arg2Of cells,of
R3222 T4002 T4001 arg1Of cells,PKD1/3−/−
R3223 T4003 T3989 arg2Of suggests,but
R3224 T4007 T4005 arg1Of differences,these
R3225 T4007 T4006 arg1Of differences,small
R3226 T4007 T4008 arg1Of differences,were
R3227 T4007 T4017 arg1Of differences,were
R3228 T4007 T4019 arg2Of differences,caused
R3229 T4008 T4010 arg1Of were,likely
R3230 T4008 T4016 arg1Of were,and
R3231 T4010 T4009 arg1Of likely,most
R3232 T4012 T4008 arg2Of result,were
R3233 T4012 T4011 arg1Of result,the
R3234 T4012 T4013 arg1Of result,of
R3235 T4015 T4013 arg2Of variation,of
R3236 T4015 T4014 arg1Of variation,clonal
R3237 T4016 T4003 arg2Of and,suggests
R3238 T4016 T4004 arg1Of and,that
R3239 T4019 T4016 arg2Of caused,and
R3240 T4019 T4017 arg2Of caused,were
R3241 T4019 T4018 arg1Of caused,not
R3242 T4019 T4020 arg1Of caused,specifically
R3243 T4022 T4019 arg1Of loss,caused
R3244 T4022 T4021 arg2Of loss,by
R3245 T4022 T4023 arg1Of loss,of
R3246 T4025 T4023 arg2Of enzymes,of
R3247 T4025 T4024 arg1Of enzymes,PKD
R3248 T4030 T4028 arg1Of enzymes,PKD
R3249 T4030 T4029 arg1Of enzymes,family
R3250 T4030 T4031 arg1Of enzymes,are
R3251 T4030 T4033 arg1Of enzymes,essential
R3252 T4031 T4026 arg1Of are,Thus
R3253 T4031 T4027 arg1Of are,","
R3254 T4031 T4032 arg1Of are,not
R3255 T4033 T4031 arg2Of essential,are
R3256 T4033 T4034 arg1Of essential,for
R3257 T4035 T4034 arg2Of regulating,for
R3258 T4037 T4036 arg1Of survival,basal
R3259 T4037 T4038 arg1Of survival,and
R3260 T4038 T4035 arg2Of and,regulating
R3261 T4039 T4038 arg2Of proliferation,and
R3262 T4039 T4040 arg1Of proliferation,of
R3263 T4043 T4040 arg2Of cells,of
R3264 T4043 T4041 arg1Of cells,DT40
R3265 T4043 T4042 arg1Of cells,B
R3266 T4045 T4044 arg1Of enzymes,PKD
R3267 T4045 T4046 arg1Of enzymes,","
R3268 T4045 T4052 arg1Of enzymes,have
R3269 T4045 T4054 arg1Of enzymes,been
R3270 T4045 T4055 arg2Of enzymes,linked
R3271 T4048 T4049 arg1Of PKD1,and
R3272 T4049 T4046 arg2Of and,","
R3273 T4049 T4047 arg1Of and,specifically
R3274 T4050 T4049 arg2Of PKD2,and
R3275 T4055 T4051 arg1Of linked,","
R3276 T4055 T4052 arg2Of linked,have
R3277 T4055 T4053 arg1Of linked,previously
R3278 T4055 T4054 arg2Of linked,been
R3279 T4055 T4056 arg1Of linked,to
R3280 T4059 T4056 arg2Of role,to
R3281 T4059 T4057 arg1Of role,a
R3282 T4059 T4058 arg1Of role,protective
R3283 T4059 T4060 arg1Of role,against
R3284 T4062 T4061 arg1Of stress-induced,oxidative
R3285 T4063 T4060 arg2Of injury,against
R3286 T4063 T4062 arg1Of injury,stress-induced
R3287 T4063 T4064 arg1Of injury,in
R3288 T4066 T4067 arg1Of fibroblast,","
R3289 T4068 T4067 arg2Of HeLa,","
R3290 T4072 T4064 arg2Of lines,in
R3291 T4072 T4065 arg1Of lines,3T3
R3292 T4072 T4066 arg1Of lines,fibroblast
R3293 T4072 T4068 arg1Of lines,HeLa
R3294 T4072 T4069 arg1Of lines,and
R3295 T4072 T4070 arg1Of lines,epithelial
R3296 T4072 T4071 arg1Of lines,cell
R3297 T4072 T4073 arg1Of lines,[
R3298 T4074 T4073 arg2Of "17,30–32",[
R3299 T4075 T4073 arg3Of ],[
R3300 T4076 T4078 arg1Of We,addressed
R3301 T4078 T4077 arg1Of addressed,therefore
R3302 T4080 T4078 arg2Of role,addressed
R3303 T4080 T4079 arg1Of role,the
R3304 T4080 T4081 arg1Of role,of
R3305 T4080 T4085 arg1Of role,in
R3306 T4084 T4081 arg2Of kinases,of
R3307 T4084 T4082 arg1Of kinases,PKD
R3308 T4084 T4083 arg1Of kinases,family
R3309 T4086 T4085 arg2Of regulating,in
R3310 T4086 T4090 arg1Of regulating,in
R3311 T4089 T4086 arg2Of survival,regulating
R3312 T4089 T4087 arg1Of survival,B
R3313 T4089 T4088 arg1Of survival,cell
R3314 T4090 T4092 arg1Of in,to
R3315 T4091 T4090 arg2Of response,in
R3316 T4094 T4093 arg1Of stress,oxidative
R3317 T4094 T4095 arg1Of stress,and
R3318 T4095 T4090 arg3Of and,in
R3319 T4098 T4095 arg2Of stimuli,and
R3320 T4098 T4096 arg1Of stimuli,other
R3321 T4098 T4097 arg1Of stimuli,stress
R3322 T4100 T4099 arg2Of shown,As
R3323 T4100 T4101 arg1Of shown,in
R3324 T4103 T4101 arg2Of 2B,in
R3325 T4103 T4102 arg1Of 2B,Fig.
R3326 T4105 T4106 arg1Of loss,of
R3327 T4105 T4109 arg1Of loss,had
R3328 T4108 T4106 arg2Of expression,of
R3329 T4108 T4107 arg1Of expression,PKD1/3
R3330 T4109 T4099 arg1Of had,As
R3331 T4109 T4104 arg1Of had,","
R3332 T4109 T4113 arg1Of had,on
R3333 T4109 T4120 arg1Of had,in
R3334 T4109 T4153 arg1Of had,following
R3335 T4112 T4109 arg2Of impact,had
R3336 T4112 T4110 arg1Of impact,no
R3337 T4112 T4111 arg1Of impact,significant
R3338 T4115 T4113 arg2Of survival,on
R3339 T4115 T4114 arg1Of survival,the
R3340 T4115 T4116 arg1Of survival,of
R3341 T4119 T4116 arg2Of cells,of
R3342 T4119 T4117 arg1Of cells,DT40
R3343 T4119 T4118 arg1Of cells,B
R3344 T4120 T4122 arg1Of in,to
R3345 T4120 T4152 arg1Of in,or
R3346 T4121 T4120 arg2Of response,in
R3347 T4125 T4123 arg1Of stimuli,mitochondrial
R3348 T4125 T4124 arg1Of stimuli,stress
R3349 T4125 T4126 arg1Of stimuli,(
R3350 T4125 T4132 arg1Of stimuli,;
R3351 T4127 T4128 arg1Of H2O2,or
R3352 T4128 T4126 arg2Of or,(
R3353 T4130 T4128 arg2Of deprivation,or
R3354 T4130 T4129 arg1Of deprivation,serum
R3355 T4131 T4126 arg3Of ),(
R3356 T4132 T4141 arg1Of ;,;
R3357 T4135 T4132 arg2Of agents,;
R3358 T4135 T4133 arg1Of agents,DNA
R3359 T4135 T4134 arg1Of agents,damaging
R3360 T4135 T4136 arg1Of agents,(
R3361 T4137 T4138 arg1Of etoposide,or
R3362 T4138 T4136 arg2Of or,(
R3363 T4139 T4138 arg2Of doxorubicin,or
R3364 T4140 T4136 arg3Of ),(
R3365 T4141 T4120 arg3Of ;,in
R3366 T4144 T4141 arg2Of stress,;
R3367 T4144 T4142 arg1Of stress,ER
R3368 T4144 T4143 arg1Of stress,pathway
R3369 T4144 T4145 arg1Of stress,due
R3370 T4145 T4146 arg1Of due,to
R3371 T4148 T4145 arg2Of overload,due
R3372 T4148 T4147 arg1Of overload,calcium
R3373 T4148 T4149 arg1Of overload,(
R3374 T4150 T4149 arg2Of thapsigargin,(
R3375 T4151 T4149 arg3Of ),(
R3376 T4153 T4152 arg2Of following,or
R3377 T4155 T4153 arg2Of treatment,following
R3378 T4155 T4154 arg2Of treatment,prolonged
R3379 T4155 T4156 arg1Of treatment,with
R3380 T4158 T4157 arg1Of esters,phorbol
R3381 T4158 T4159 arg1Of esters,or
R3382 T4159 T4156 arg2Of or,with
R3383 T4159 T4162 arg1Of or,","
R3384 T4161 T4159 arg2Of A,or
R3385 T4161 T4160 arg1Of A,Trichostatin
R3386 T4164 T4162 arg2Of inhibitor,","
R3387 T4164 T4163 arg1Of inhibitor,an
R3388 T4164 T4165 arg1Of inhibitor,of
R3389 T4168 T4165 arg2Of HDACs,of
R3390 T4168 T4166 arg1Of HDACs,class
R3391 T4168 T4167 arg1Of HDACs,I/II
R3392 T4172 T4171 arg1Of kinases,PKD
R3393 T4172 T4173 arg1Of kinases,do
R3394 T4172 T4175 arg1Of kinases,play
R3395 T4175 T4169 arg1Of play,Thus
R3396 T4175 T4170 arg1Of play,","
R3397 T4175 T4173 arg2Of play,do
R3398 T4175 T4174 arg1Of play,not
R3399 T4175 T4179 arg1Of play,in
R3400 T4178 T4175 arg2Of role,play
R3401 T4178 T4176 arg1Of role,an
R3402 T4178 T4177 arg1Of role,essential
R3403 T4180 T4179 arg2Of regulating,in
R3404 T4180 T4184 arg1Of regulating,in
R3405 T4183 T4180 arg2Of survival,regulating
R3406 T4183 T4181 arg1Of survival,B
R3407 T4183 T4182 arg1Of survival,cell
R3408 T4184 T4186 arg1Of in,to
R3409 T4185 T4184 arg2Of response,in
R3410 T4188 T4184 arg3Of range,in
R3411 T4188 T4187 arg1Of range,a
R3412 T4188 T4189 arg1Of range,of
R3413 T4192 T4189 arg2Of stimuli,of
R3414 T4192 T4190 arg1Of stimuli,different
R3415 T4192 T4191 arg1Of stimuli,stress

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T4218 5-13 NNP denotes Cellular
T4219 14-27 NN denotes proliferation
T4220 28-31 CC denotes and
T4221 32-40 NN denotes survival
T4222 41-43 IN denotes in
T4223 44-48 NNP denotes DT40
T4224 49-50 NNP denotes B
T4225 51-56 NNS denotes cells
T4226 57-64 VBG denotes lacking
T4227 65-75 NN denotes expression
T4228 76-78 IN denotes of
T4229 79-82 NNP denotes PKD
T4230 83-89 NN denotes family
T4231 90-97 VBZ denotes kinases
T4232 98-101 NNP denotes PKD
T4233 102-109 NNS denotes enzymes
T4234 110-114 VBP denotes have
T4235 115-125 RB denotes previously
T4236 126-130 VBN denotes been
T4237 131-137 VBN denotes linked
T4238 138-140 TO denotes to
T4239 141-144 DT denotes the
T4240 145-155 NN denotes regulation
T4241 156-158 IN denotes of
T4242 159-163 NN denotes cell
T4243 164-177 NN denotes proliferation
T4244 178-181 CC denotes and
T4245 182-190 NN denotes survival
T4246 191-192 -LRB- denotes (
T4247 192-200 VBN denotes reviewed
T4276 347-349 IN denotes in
T4277 350-353 DT denotes the
T4278 354-362 NN denotes presence
T4279 363-364 -LRB- denotes (
T4280 364-370 CD denotes PKD1/3
T4281 370-371 CD denotes −
T4282 371-372 NN denotes /
T4283 372-373 NN denotes −
T4284 373-374 : denotes :
T4285 375-384 NN denotes Flag-PKD3
T4286 384-385 NN denotes +
T4287 385-387 NN denotes ve
T4288 387-388 -RRB- denotes )
T4289 389-391 CC denotes or
T4290 392-399 NN denotes absence
T4291 400-401 -LRB- denotes (
T4292 401-407 CD denotes PKD1/3
T4293 407-408 CD denotes −
T4294 408-409 NN denotes /
T4295 409-410 NN denotes −
T4296 410-411 -RRB- denotes )
T4297 412-414 IN denotes of
T4298 415-426 NN denotes doxycycline
T4299 427-430 CC denotes and
T4300 431-440 VBD denotes monitored
T4301 441-452 JJ denotes exponential
T4302 453-459 NN denotes growth
T4303 459-460 . denotes .
T4304 461-463 IN denotes As
T4305 464-469 VBN denotes shown
T4306 470-472 IN denotes in
T4307 473-477 NNP denotes Fig.
T4308 478-480 NNP denotes 2A
T4309 480-481 , denotes ,
T4310 482-488 NNP denotes PKD1/3
T4311 488-489 VBD denotes −
T4312 489-490 CD denotes /
T4313 490-491 NN denotes −
T4314 492-497 NNS denotes cells
T4315 498-510 VBD denotes proliferated
T4316 511-524 RB denotes exponentially
T4317 525-528 CC denotes and
T4318 529-542 NN denotes re-expression
T4319 543-545 IN denotes of
T4320 546-555 NN denotes Flag-PKD3
T4321 556-558 IN denotes in
T4322 559-564 DT denotes these
T4323 565-570 NNS denotes cells
T4324 571-574 VBD denotes had
T4325 575-577 DT denotes no
T4326 578-584 NN denotes impact
T4327 585-587 IN denotes on
T4328 588-591 DT denotes the
T4329 592-596 NN denotes rate
T4330 597-599 IN denotes of
T4331 600-613 NN denotes proliferation
T4332 613-614 . denotes .
T4333 615-626 RB denotes Furthermore
T4334 626-627 , denotes ,
T4335 628-631 DT denotes the
T4336 632-641 NN denotes viability
T4337 642-644 IN denotes of
T4338 645-651 CD denotes PKD1/3
T4339 651-652 CD denotes −
T4340 652-653 NN denotes /
T4341 653-654 NN denotes −
T4342 655-656 NNP denotes B
T4343 657-662 NNS denotes cells
T4344 663-669 IN denotes during
T4345 670-677 JJ denotes routine
T4346 678-687 NN denotes culturing
T4347 688-691 VBD denotes was
T4348 692-695 RB denotes not
T4349 696-709 RB denotes significantly
T4350 710-719 JJ denotes different
T4351 720-724 IN denotes from
T4352 725-729 DT denotes that
T4353 730-732 IN denotes of
T4354 733-742 JJ denotes wild-type
T4355 743-744 NNP denotes B
T4356 745-750 NNS denotes cells
T4357 751-752 -LRB- denotes (
T4358 752-756 NNS denotes data
T4359 757-760 RB denotes not
T4360 761-766 VBN denotes shown
T4361 766-767 -RRB- denotes )
T4362 767-768 . denotes .
T4363 769-771 PRP denotes It
T4364 772-775 VBD denotes was
T4365 776-781 VBN denotes noted
T4366 782-786 IN denotes that
T4367 787-790 DT denotes the
T4368 791-801 NN denotes population
T4369 802-810 VBG denotes doubling
T4370 811-815 NN denotes time
T4371 816-818 IN denotes of
T4372 819-825 CD denotes PKD1/3
T4373 825-826 CD denotes −
T4374 826-827 NN denotes /
T4375 827-828 NN denotes −
T4376 829-834 NNS denotes cells
T4377 835-838 VBD denotes was
T4378 839-847 RB denotes slightly
T4379 848-854 JJR denotes slower
T4380 855-859 IN denotes than
T4381 860-864 DT denotes that
T4382 865-867 IN denotes of
T4383 868-872 JJ denotes wild
T4384 873-877 NN denotes type
T4385 878-882 CD denotes DT40
T4386 883-888 NNS denotes cells
T4387 889-890 -LRB- denotes (
T4388 890-894 CD denotes 12.7
T4389 895-896 CD denotes ±
T4390 897-900 CD denotes 2.8
T4391 901-902 NN denotes h
T4392 903-909 IN denotes versus
T4393 910-914 CD denotes 10.2
T4394 915-916 CD denotes ±
T4395 917-920 CD denotes 0.4
T4396 921-922 NN denotes h
T4397 922-923 -RRB- denotes )
T4398 924-927 CC denotes but
T4399 928-931 DT denotes the
T4400 932-939 NN denotes failure
T4401 940-942 IN denotes of
T4402 943-947 CD denotes PKD3
T4403 948-961 NN denotes re-expression
T4404 962-964 TO denotes to
T4405 965-971 VB denotes modify
T4406 972-975 DT denotes the
T4407 976-989 NN denotes proliferation
T4408 990-994 NN denotes rate
T4409 995-997 IN denotes of
T4410 998-1004 CD denotes PKD1/3
T4411 1004-1005 CD denotes −
T4412 1005-1006 NN denotes /
T4413 1006-1007 NN denotes −
T4414 1008-1013 NNS denotes cells
T4415 1014-1022 VBZ denotes suggests
T4416 1023-1027 IN denotes that
T4417 1028-1033 DT denotes these
T4418 1034-1039 JJ denotes small
T4419 1040-1051 NNS denotes differences
T4420 1052-1056 VBD denotes were
T4421 1057-1061 RBS denotes most
T4422 1062-1068 JJ denotes likely
T4423 1069-1072 DT denotes the
T4424 1073-1079 NN denotes result
T4425 1080-1082 IN denotes of
T4426 1083-1089 JJ denotes clonal
T4427 1090-1099 NN denotes variation
T4428 1100-1103 CC denotes and
T4429 1104-1108 VBD denotes were
T4430 1109-1112 RB denotes not
T4431 1113-1119 VBN denotes caused
T4432 1120-1132 RB denotes specifically
T4433 1133-1135 IN denotes by
T4434 1136-1140 NN denotes loss
T4435 1141-1143 IN denotes of
T4436 1144-1147 NNP denotes PKD
T4437 1148-1155 VBZ denotes enzymes
T4438 1155-1156 . denotes .
T4439 1157-1161 RB denotes Thus
T4440 1161-1162 , denotes ,
T4441 1163-1166 NNP denotes PKD
T4442 1167-1173 NN denotes family
T4443 1174-1181 NNS denotes enzymes
T4444 1182-1185 VBP denotes are
T4445 1186-1189 RB denotes not
T4446 1190-1199 JJ denotes essential
T4447 1200-1203 IN denotes for
T4448 1204-1214 VBG denotes regulating
T4449 1215-1220 JJ denotes basal
T4450 1221-1229 NN denotes survival
T4451 1230-1233 CC denotes and
T4452 1234-1247 NN denotes proliferation
T4453 1248-1250 IN denotes of
T4454 1251-1255 NNP denotes DT40
T4455 1256-1257 NNP denotes B
T4456 1258-1263 NNS denotes cells
T4457 1263-1264 . denotes .
T4458 1265-1268 NNP denotes PKD
T4459 1269-1276 VBZ denotes enzymes
T4460 1276-1277 , denotes ,
T4461 1278-1290 RB denotes specifically
T4462 1291-1295 CD denotes PKD1
T4463 1296-1299 CC denotes and
T4464 1300-1304 NNP denotes PKD2
T4465 1304-1305 , denotes ,
T4466 1306-1310 VBP denotes have
T4467 1311-1321 RB denotes previously
T4468 1322-1326 VBN denotes been
T4469 1327-1333 VBN denotes linked
T4470 1334-1336 TO denotes to
T4471 1337-1338 DT denotes a
T4472 1339-1349 JJ denotes protective
T4473 1350-1354 NN denotes role
T4474 1355-1362 IN denotes against
T4475 1363-1372 JJ denotes oxidative
T4476 1373-1387 JJ denotes stress-induced
T4477 1388-1394 NN denotes injury
T4478 1395-1397 IN denotes in
T4479 1398-1401 NNP denotes 3T3
T4480 1402-1412 NN denotes fibroblast
T4481 1412-1413 , denotes ,
T4482 1414-1418 NNP denotes HeLa
T4483 1419-1422 CC denotes and
T4484 1423-1433 JJ denotes epithelial
T4485 1434-1438 NN denotes cell
T4486 1439-1444 NNS denotes lines
T4487 1445-1446 NNP denotes [
T4488 1446-1451 CD denotes 17,30
T4489 1452-1454 CD denotes 32
T4490 1454-1455 NN denotes ]
T4491 1455-1456 . denotes .
T4492 1457-1459 PRP denotes We
T4493 1460-1469 RB denotes therefore
T4494 1470-1479 VBD denotes addressed
T4495 1480-1483 DT denotes the
T4496 1484-1488 NN denotes role
T4497 1489-1491 IN denotes of
T4498 1492-1495 NNP denotes PKD
T4499 1496-1502 NN denotes family
T4500 1503-1510 NNS denotes kinases
T4501 1511-1513 IN denotes in
T4502 1514-1524 VBG denotes regulating
T4503 1525-1526 NNP denotes B
T4504 1527-1531 NN denotes cell
T4505 1532-1540 NN denotes survival
T4506 1541-1543 IN denotes in
T4507 1544-1552 NN denotes response
T4508 1553-1555 TO denotes to
T4509 1556-1565 JJ denotes oxidative
T4510 1566-1572 NN denotes stress
T4511 1573-1576 CC denotes and
T4512 1577-1582 JJ denotes other
T4513 1583-1589 NN denotes stress
T4514 1590-1597 NNS denotes stimuli
T4515 1597-1598 . denotes .
T4516 1599-1601 IN denotes As
T4517 1602-1607 VBN denotes shown
T4518 1608-1610 IN denotes in
T4519 1611-1615 NNP denotes Fig.
T4520 1616-1618 NNP denotes 2B
T4521 1618-1619 , denotes ,
T4522 1620-1624 NN denotes loss
T4523 1625-1627 IN denotes of
T4524 1628-1634 CD denotes PKD1/3
T4525 1635-1645 NN denotes expression
T4526 1646-1649 VBD denotes had
T4527 1650-1652 DT denotes no
T4528 1653-1664 JJ denotes significant
T4529 1665-1671 NN denotes impact
T4530 1672-1674 IN denotes on
T4531 1675-1678 DT denotes the
T4532 1679-1687 NN denotes survival
T4533 1688-1690 IN denotes of
T4534 1691-1695 NNP denotes DT40
T4535 1696-1697 NNP denotes B
T4536 1698-1703 NNS denotes cells
T4537 1704-1706 IN denotes in
T4538 1707-1715 NN denotes response
T4539 1716-1718 TO denotes to
T4540 1719-1732 JJ denotes mitochondrial
T4541 1733-1739 NN denotes stress
T4542 1740-1747 NNS denotes stimuli
T4543 1748-1749 -LRB- denotes (
T4544 1749-1753 CD denotes H2O2
T4545 1754-1756 CC denotes or
T4546 1757-1762 NN denotes serum
T4547 1763-1774 NN denotes deprivation
T4548 1774-1775 -RRB- denotes )
T4549 1775-1776 : denotes ;
T4550 1777-1780 NNP denotes DNA
T4551 1781-1789 VBG denotes damaging
T4552 1790-1796 NNS denotes agents
T4553 1797-1798 -LRB- denotes (
T4554 1798-1807 NN denotes etoposide
T4555 1808-1810 CC denotes or
T4556 1811-1822 NN denotes doxorubicin
T4557 1822-1823 -RRB- denotes )
T4558 1823-1824 : denotes ;
T4559 1825-1827 NNP denotes ER
T4560 1828-1835 NN denotes pathway
T4561 1836-1842 NN denotes stress
T4562 1843-1846 JJ denotes due
T4563 1847-1849 TO denotes to
T4564 1850-1857 NN denotes calcium
T4565 1858-1866 NN denotes overload
T4566 1867-1868 -LRB- denotes (
T4567 1868-1880 NN denotes thapsigargin
T4568 1880-1881 -RRB- denotes )
T4569 1882-1884 CC denotes or
T4570 1885-1894 VBG denotes following
T4571 1895-1904 JJ denotes prolonged
T4572 1905-1914 NN denotes treatment
T4573 1915-1919 IN denotes with
T4574 1920-1927 NN denotes phorbol
T4575 1928-1934 NNS denotes esters
T4576 1935-1937 CC denotes or
T4577 1938-1950 NNP denotes Trichostatin
T4578 1951-1952 NNP denotes A
T4579 1952-1953 , denotes ,
T4580 1954-1956 DT denotes an
T4581 1957-1966 NN denotes inhibitor
T4582 1967-1969 IN denotes of
T4583 1970-1975 NN denotes class
T4584 1976-1980 NNP denotes I/II
T4585 1981-1986 NNP denotes HDACs
T4586 1986-1987 . denotes .
T4587 1988-1992 RB denotes Thus
T4588 1992-1993 , denotes ,
T4589 1994-1997 NNP denotes PKD
T4590 1998-2005 NNS denotes kinases
T4591 2006-2008 VBP denotes do
T4592 2009-2012 RB denotes not
T4593 2013-2017 VB denotes play
T4594 2018-2020 DT denotes an
T4595 2021-2030 JJ denotes essential
T4596 2031-2035 NN denotes role
T4597 2036-2038 IN denotes in
T4598 2039-2049 VBG denotes regulating
T4599 2050-2051 NNP denotes B
T4600 2052-2056 NN denotes cell
T4601 2057-2065 NN denotes survival
T4602 2066-2068 IN denotes in
T4603 2069-2077 NN denotes response
T4604 2078-2080 TO denotes to
T4605 2081-2082 DT denotes a
T4606 2083-2088 NN denotes range
T4607 2089-2091 IN denotes of
T4608 2092-2101 JJ denotes different
T4609 2102-2108 NN denotes stress
T4610 2109-2116 NNS denotes stimuli
T4611 2116-2117 . denotes .
T4248 201-203 IN denotes in
T4249 204-205 NNP denotes [
T4250 205-207 CD denotes 20
T4251 207-208 NNP denotes ]
T4252 208-209 -RRB- denotes )
T4253 209-210 . denotes .
T4254 211-213 TO denotes To
T4255 214-225 VB denotes investigate
T4256 226-229 DT denotes the
T4257 230-236 NN denotes effect
T4258 237-241 WDT denotes that
T4259 242-246 NN denotes loss
T4260 247-249 IN denotes of
T4261 250-253 NNP denotes PKD
T4262 254-261 NNS denotes kinases
T4263 262-265 VBD denotes had
T4264 266-268 IN denotes on
T4265 269-270 NNP denotes B
T4266 271-275 NN denotes cell
T4267 276-284 NN denotes survival
T4268 285-291 CC denotes and/or
T4269 292-305 NN denotes proliferation
T4270 306-308 PRP denotes we
T4271 309-317 VBD denotes cultured
T4272 318-327 JJ denotes wild-type
T4273 328-331 CC denotes and
T4274 332-340 JJ denotes PKD-null
T4275 341-346 NNS denotes cells
R3417 T4218 T4219 compound Cellular,proliferation
R3418 T4219 T4231 nsubj proliferation,kinases
R3419 T4220 T4219 cc and,proliferation
R3420 T4221 T4219 conj survival,proliferation
R3421 T4222 T4219 prep in,proliferation
R3422 T4223 T4224 compound DT40,B
R3423 T4224 T4225 compound B,cells
R3424 T4225 T4222 pobj cells,in
R3425 T4226 T4231 advcl lacking,kinases
R3426 T4227 T4226 dobj expression,lacking
R3427 T4228 T4227 prep of,expression
R3428 T4229 T4230 compound PKD,family
R3429 T4230 T4228 pobj family,of
R3430 T4231 T4231 ROOT kinases,kinases
R3431 T4232 T4233 compound PKD,enzymes
R3432 T4233 T4237 nsubjpass enzymes,linked
R3433 T4234 T4237 aux have,linked
R3434 T4235 T4237 advmod previously,linked
R3435 T4236 T4237 auxpass been,linked
R3436 T4237 T4231 ccomp linked,kinases
R3437 T4238 T4237 prep to,linked
R3438 T4239 T4240 det the,regulation
R3439 T4240 T4238 pobj regulation,to
R3440 T4241 T4240 prep of,regulation
R3441 T4242 T4243 compound cell,proliferation
R3442 T4243 T4241 pobj proliferation,of
R3443 T4244 T4243 cc and,proliferation
R3444 T4245 T4243 conj survival,proliferation
R3445 T4246 T4243 punct (,proliferation
R3446 T4247 T4240 acl reviewed,regulation
R3447 T4248 T4247 prep in,reviewed
R3448 T4249 T4248 pobj [,in
R3449 T4250 T4251 nummod 20,]
R3450 T4251 T4249 appos ],[
R3451 T4252 T4249 punct ),[
R3452 T4253 T4231 punct .,kinases
R3453 T4254 T4255 aux To,investigate
R3454 T4255 T4271 advcl investigate,cultured
R3455 T4256 T4257 det the,effect
R3456 T4257 T4255 dobj effect,investigate
R3457 T4258 T4263 dobj that,had
R3458 T4259 T4263 nsubj loss,had
R3459 T4260 T4259 prep of,loss
R3460 T4261 T4262 compound PKD,kinases
R3461 T4262 T4260 pobj kinases,of
R3462 T4263 T4257 relcl had,effect
R3463 T4264 T4263 prep on,had
R3464 T4265 T4267 compound B,survival
R3465 T4266 T4267 compound cell,survival
R3466 T4267 T4264 pobj survival,on
R3467 T4268 T4263 cc and/or,had
R3468 T4269 T4271 dobj proliferation,cultured
R3469 T4270 T4271 nsubj we,cultured
R3470 T4271 T4271 ROOT cultured,cultured
R3471 T4272 T4275 amod wild-type,cells
R3472 T4273 T4272 cc and,wild-type
R3473 T4274 T4272 conj PKD-null,wild-type
R3474 T4275 T4271 dobj cells,cultured
R3475 T4276 T4271 prep in,cultured
R3476 T4277 T4278 det the,presence
R3477 T4278 T4276 pobj presence,in
R3478 T4279 T4278 punct (,presence
R3479 T4280 T4300 nsubj PKD1/3,monitored
R3480 T4281 T4283 nummod −,−
R3481 T4282 T4283 compound /,−
R3482 T4283 T4300 dep −,monitored
R3483 T4284 T4283 punct :,−
R3484 T4285 T4287 nmod Flag-PKD3,ve
R3485 T4286 T4287 compound +,ve
R3486 T4287 T4283 appos ve,−
R3487 T4288 T4287 punct ),ve
R3488 T4289 T4287 cc or,ve
R3489 T4290 T4287 conj absence,ve
R3490 T4291 T4290 punct (,absence
R3491 T4292 T4295 nummod PKD1/3,−
R3492 T4293 T4295 nummod −,−
R3493 T4294 T4295 compound /,−
R3494 T4295 T4290 appos −,absence
R3495 T4296 T4295 punct ),−
R3496 T4297 T4290 prep of,absence
R3497 T4298 T4297 pobj doxycycline,of
R3498 T4299 T4290 cc and,absence
R3499 T4300 T4271 advcl monitored,cultured
R3500 T4301 T4302 amod exponential,growth
R3501 T4302 T4300 dobj growth,monitored
R3502 T4303 T4271 punct .,cultured
R3503 T4304 T4305 mark As,shown
R3504 T4305 T4311 advcl shown,−
R3505 T4306 T4305 prep in,shown
R3506 T4307 T4308 compound Fig.,2A
R3507 T4308 T4306 pobj 2A,in
R3508 T4309 T4311 punct ",",−
R3509 T4310 T4311 nsubj PKD1/3,−
R3510 T4311 T4311 ROOT −,−
R3511 T4312 T4314 nummod /,cells
R3512 T4313 T4314 compound −,cells
R3513 T4314 T4315 nsubj cells,proliferated
R3514 T4315 T4311 ccomp proliferated,−
R3515 T4316 T4315 advmod exponentially,proliferated
R3516 T4317 T4315 cc and,proliferated
R3517 T4318 T4324 nsubj re-expression,had
R3518 T4319 T4318 prep of,re-expression
R3519 T4320 T4319 pobj Flag-PKD3,of
R3520 T4321 T4318 prep in,re-expression
R3521 T4322 T4323 det these,cells
R3522 T4323 T4321 pobj cells,in
R3523 T4324 T4315 conj had,proliferated
R3524 T4325 T4326 det no,impact
R3525 T4326 T4324 dobj impact,had
R3526 T4327 T4326 prep on,impact
R3527 T4328 T4329 det the,rate
R3528 T4329 T4327 pobj rate,on
R3529 T4330 T4329 prep of,rate
R3530 T4331 T4330 pobj proliferation,of
R3531 T4332 T4311 punct .,−
R3532 T4333 T4347 advmod Furthermore,was
R3533 T4334 T4347 punct ",",was
R3534 T4335 T4336 det the,viability
R3535 T4336 T4347 nsubj viability,was
R3536 T4337 T4336 prep of,viability
R3537 T4338 T4343 nummod PKD1/3,cells
R3538 T4339 T4343 nummod −,cells
R3539 T4340 T4343 compound /,cells
R3540 T4341 T4343 compound −,cells
R3541 T4342 T4343 compound B,cells
R3542 T4343 T4337 pobj cells,of
R3543 T4344 T4336 prep during,viability
R3544 T4345 T4346 amod routine,culturing
R3545 T4346 T4344 pobj culturing,during
R3546 T4347 T4347 ROOT was,was
R3547 T4348 T4347 neg not,was
R3548 T4349 T4350 advmod significantly,different
R3549 T4350 T4347 acomp different,was
R3550 T4351 T4350 prep from,different
R3551 T4352 T4351 pobj that,from
R3552 T4353 T4352 prep of,that
R3553 T4354 T4356 amod wild-type,cells
R3554 T4355 T4356 compound B,cells
R3555 T4356 T4353 pobj cells,of
R3556 T4357 T4360 punct (,shown
R3557 T4358 T4360 nsubjpass data,shown
R3558 T4359 T4360 neg not,shown
R3559 T4360 T4347 conj shown,was
R3560 T4361 T4360 punct ),shown
R3561 T4362 T4347 punct .,was
R3562 T4363 T4365 nsubjpass It,noted
R3563 T4364 T4365 auxpass was,noted
R3564 T4365 T4365 ROOT noted,noted
R3565 T4366 T4377 mark that,was
R3566 T4367 T4370 det the,time
R3567 T4368 T4369 compound population,doubling
R3568 T4369 T4370 amod doubling,time
R3569 T4370 T4377 nsubj time,was
R3570 T4371 T4370 prep of,time
R3571 T4372 T4376 nummod PKD1/3,cells
R3572 T4373 T4376 nummod −,cells
R3573 T4374 T4376 compound /,cells
R3574 T4375 T4376 compound −,cells
R3575 T4376 T4371 pobj cells,of
R3576 T4377 T4365 ccomp was,noted
R3577 T4378 T4379 advmod slightly,slower
R3578 T4379 T4377 acomp slower,was
R3579 T4380 T4379 prep than,slower
R3580 T4381 T4380 pobj that,than
R3581 T4382 T4381 prep of,that
R3582 T4383 T4384 amod wild,type
R3583 T4384 T4382 pobj type,of
R3584 T4385 T4386 nummod DT40,cells
R3585 T4386 T4384 appos cells,type
R3586 T4387 T4386 punct (,cells
R3587 T4388 T4391 nummod 12.7,h
R3588 T4389 T4391 nmod ±,h
R3589 T4390 T4391 nummod 2.8,h
R3590 T4391 T4386 appos h,cells
R3591 T4392 T4391 prep versus,h
R3592 T4393 T4396 nummod 10.2,h
R3593 T4394 T4396 nmod ±,h
R3594 T4395 T4396 nummod 0.4,h
R3595 T4396 T4392 pobj h,versus
R3596 T4397 T4386 punct ),cells
R3597 T4398 T4365 cc but,noted
R3598 T4399 T4400 det the,failure
R3599 T4400 T4415 nsubj failure,suggests
R3600 T4401 T4400 prep of,failure
R3601 T4402 T4403 nummod PKD3,re-expression
R3602 T4403 T4401 pobj re-expression,of
R3603 T4404 T4405 aux to,modify
R3604 T4405 T4400 acl modify,failure
R3605 T4406 T4408 det the,rate
R3606 T4407 T4408 compound proliferation,rate
R3607 T4408 T4405 dobj rate,modify
R3608 T4409 T4408 prep of,rate
R3609 T4410 T4414 nummod PKD1/3,cells
R3610 T4411 T4414 nummod −,cells
R3611 T4412 T4414 compound /,cells
R3612 T4413 T4414 compound −,cells
R3613 T4414 T4409 pobj cells,of
R3614 T4415 T4365 conj suggests,noted
R3615 T4416 T4420 mark that,were
R3616 T4417 T4419 det these,differences
R3617 T4418 T4419 amod small,differences
R3618 T4419 T4420 nsubj differences,were
R3619 T4420 T4415 ccomp were,suggests
R3620 T4421 T4422 advmod most,likely
R3621 T4422 T4420 acomp likely,were
R3622 T4423 T4424 det the,result
R3623 T4424 T4420 attr result,were
R3624 T4425 T4424 prep of,result
R3625 T4426 T4427 amod clonal,variation
R3626 T4427 T4425 pobj variation,of
R3627 T4428 T4420 cc and,were
R3628 T4429 T4431 auxpass were,caused
R3629 T4430 T4431 neg not,caused
R3630 T4431 T4420 conj caused,were
R3631 T4432 T4431 advmod specifically,caused
R3632 T4433 T4431 agent by,caused
R3633 T4434 T4433 pobj loss,by
R3634 T4435 T4434 prep of,loss
R3635 T4436 T4437 compound PKD,enzymes
R3636 T4437 T4435 pobj enzymes,of
R3637 T4438 T4415 punct .,suggests
R3638 T4439 T4444 advmod Thus,are
R3639 T4440 T4444 punct ",",are
R3640 T4441 T4443 compound PKD,enzymes
R3641 T4442 T4443 compound family,enzymes
R3642 T4443 T4444 nsubj enzymes,are
R3643 T4444 T4444 ROOT are,are
R3644 T4445 T4444 neg not,are
R3645 T4446 T4444 acomp essential,are
R3646 T4447 T4446 prep for,essential
R3647 T4448 T4447 pcomp regulating,for
R3648 T4449 T4450 amod basal,survival
R3649 T4450 T4448 dobj survival,regulating
R3650 T4451 T4450 cc and,survival
R3658 T4459 T4469 nsubj enzymes,linked
R3659 T4460 T4459 punct ",",enzymes
R3660 T4461 T4462 advmod specifically,PKD1
R3661 T4462 T4459 appos PKD1,enzymes
R3662 T4463 T4462 cc and,PKD1
R3663 T4464 T4462 conj PKD2,PKD1
R3664 T4465 T4469 punct ",",linked
R3665 T4466 T4469 aux have,linked
R3666 T4467 T4469 advmod previously,linked
R3667 T4468 T4469 auxpass been,linked
R3668 T4469 T4469 ROOT linked,linked
R3669 T4470 T4469 prep to,linked
R3670 T4471 T4473 det a,role
R3671 T4472 T4473 amod protective,role
R3672 T4473 T4470 pobj role,to
R3673 T4474 T4473 prep against,role
R3674 T4475 T4477 amod oxidative,injury
R3675 T4476 T4477 amod stress-induced,injury
R3676 T4477 T4486 nmod injury,lines
R3677 T4478 T4477 prep in,injury
R3678 T4479 T4480 compound 3T3,fibroblast
R3679 T4480 T4478 pobj fibroblast,in
R3680 T4481 T4480 punct ",",fibroblast
R3681 T4482 T4480 conj HeLa,fibroblast
R3682 T4483 T4482 cc and,HeLa
R3683 T4484 T4486 amod epithelial,lines
R3684 T4485 T4486 compound cell,lines
R3685 T4486 T4474 pobj lines,against
R3686 T4487 T4488 compound [,"17,30"
R3687 T4488 T4486 appos "17,30",lines
R3688 T4489 T4490 nummod 32,]
R3689 T4490 T4486 appos ],lines
R3690 T4491 T4469 punct .,linked
R3691 T4492 T4494 nsubj We,addressed
R3692 T4493 T4494 advmod therefore,addressed
R3693 T4494 T4494 ROOT addressed,addressed
R3694 T4495 T4496 det the,role
R3695 T4496 T4494 dobj role,addressed
R3696 T4497 T4496 prep of,role
R3697 T4498 T4499 compound PKD,family
R3698 T4499 T4500 compound family,kinases
R3699 T4500 T4497 pobj kinases,of
R3700 T4501 T4496 prep in,role
R3701 T4502 T4501 pcomp regulating,in
R3702 T4503 T4504 compound B,cell
R3703 T4504 T4505 compound cell,survival
R3704 T4505 T4502 dobj survival,regulating
R3705 T4506 T4502 prep in,regulating
R3706 T4507 T4506 pobj response,in
R3707 T4508 T4507 prep to,response
R3708 T4509 T4510 amod oxidative,stress
R3709 T4510 T4508 pobj stress,to
R3710 T4511 T4510 cc and,stress
R3711 T4512 T4514 amod other,stimuli
R3712 T4513 T4514 compound stress,stimuli
R3713 T4514 T4510 conj stimuli,stress
R3714 T4515 T4494 punct .,addressed
R3715 T4516 T4517 mark As,shown
R3716 T4517 T4526 advcl shown,had
R3717 T4518 T4517 prep in,shown
R3718 T4519 T4520 compound Fig.,2B
R3719 T4520 T4518 pobj 2B,in
R3720 T4521 T4520 punct ",",2B
R3721 T4522 T4520 appos loss,2B
R3722 T4523 T4522 prep of,loss
R3723 T4524 T4525 nummod PKD1/3,expression
R3724 T4525 T4523 pobj expression,of
R3725 T4526 T4526 ROOT had,had
R3726 T4527 T4529 det no,impact
R3727 T4528 T4529 amod significant,impact
R3728 T4529 T4526 dobj impact,had
R3729 T4530 T4529 prep on,impact
R3730 T4531 T4532 det the,survival
R3731 T4532 T4530 pobj survival,on
R3732 T4533 T4532 prep of,survival
R3733 T4534 T4535 compound DT40,B
R3734 T4535 T4536 compound B,cells
R3735 T4536 T4533 pobj cells,of
R3736 T4537 T4526 prep in,had
R3737 T4538 T4537 pobj response,in
R3738 T4539 T4538 prep to,response
R3739 T4540 T4542 amod mitochondrial,stimuli
R3740 T4541 T4542 compound stress,stimuli
R3741 T4542 T4539 pobj stimuli,to
R3742 T4543 T4542 punct (,stimuli
R3743 T4544 T4542 appos H2O2,stimuli
R3744 T4545 T4544 cc or,H2O2
R3745 T4546 T4547 compound serum,deprivation
R3746 T4547 T4544 conj deprivation,H2O2
R3747 T4548 T4542 punct ),stimuli
R3748 T4549 T4542 punct ;,stimuli
R3749 T4550 T4552 amod DNA,agents
R3750 T4551 T4552 amod damaging,agents
R3751 T4552 T4542 conj agents,stimuli
R3752 T4553 T4552 punct (,agents
R3753 T4554 T4552 appos etoposide,agents
R3754 T4555 T4554 cc or,etoposide
R3755 T4556 T4554 conj doxorubicin,etoposide
R3756 T4557 T4552 punct ),agents
R3757 T4558 T4526 punct ;,had
R3758 T4559 T4561 compound ER,stress
R3759 T4560 T4561 compound pathway,stress
R3760 T4561 T4570 nsubj stress,following
R3761 T4562 T4561 amod due,stress
R3762 T4563 T4562 pcomp to,due
R3763 T4564 T4565 compound calcium,overload
R3764 T4565 T4562 pobj overload,due
R3765 T4566 T4567 punct (,thapsigargin
R3766 T4567 T4565 appos thapsigargin,overload
R3767 T4568 T4567 punct ),thapsigargin
R3768 T4569 T4565 cc or,overload
R3769 T4570 T4526 advcl following,had
R3770 T4571 T4572 amod prolonged,treatment
R3771 T4572 T4570 dobj treatment,following
R3772 T4573 T4572 prep with,treatment
R3773 T4574 T4575 compound phorbol,esters
R3774 T4575 T4573 pobj esters,with
R3775 T4576 T4575 cc or,esters
R3776 T4577 T4578 compound Trichostatin,A
R3777 T4578 T4575 conj A,esters
R3778 T4579 T4578 punct ",",A
R3779 T4580 T4581 det an,inhibitor
R3780 T4581 T4578 appos inhibitor,A
R3781 T4582 T4581 prep of,inhibitor
R3782 T4583 T4585 compound class,HDACs
R3783 T4584 T4585 compound I/II,HDACs
R3784 T4585 T4582 pobj HDACs,of
R3785 T4586 T4526 punct .,had
R3786 T4587 T4593 advmod Thus,play
R3787 T4588 T4593 punct ",",play
R3788 T4589 T4590 compound PKD,kinases
R3789 T4590 T4593 nsubj kinases,play
R3790 T4591 T4593 aux do,play
R3791 T4592 T4593 neg not,play
R3792 T4593 T4593 ROOT play,play
R3793 T4594 T4596 det an,role
R3794 T4595 T4596 amod essential,role
R3795 T4596 T4593 dobj role,play
R3796 T4597 T4593 prep in,play
R3797 T4598 T4597 pcomp regulating,in
R3798 T4599 T4600 compound B,cell
R3799 T4600 T4601 compound cell,survival
R3800 T4601 T4598 dobj survival,regulating
R3801 T4602 T4598 prep in,regulating
R3802 T4603 T4602 pobj response,in
R3803 T4604 T4603 prep to,response
R3804 T4605 T4606 det a,range
R3805 T4606 T4604 pobj range,to
R3806 T4607 T4606 prep of,range
R3807 T4608 T4610 amod different,stimuli
R3808 T4609 T4610 compound stress,stimuli
R3809 T4610 T4607 pobj stimuli,of
R3810 T4611 T4593 punct .,play
R3651 T4452 T4450 conj proliferation,survival
R3652 T4453 T4452 prep of,proliferation
R3653 T4454 T4455 compound DT40,B
R3654 T4455 T4456 compound B,cells
R3655 T4456 T4453 pobj cells,of
R3656 T4457 T4444 punct .,are
R3657 T4458 T4459 compound PKD,enzymes

UBERON-AE

Id Subject Object Predicate Lexical cue
T3782 1757-1762 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

GO-BP

Id Subject Object Predicate Lexical cue
T3833 1544-1572 http://purl.obolibrary.org/obo/GO_1902884 denotes response to oxidative stress
T3834 1544-1572 http://purl.obolibrary.org/obo/GO_0034599 denotes response to oxidative stress
T3835 1707-1739 http://purl.obolibrary.org/obo/GO_1990046 denotes response to mitochondrial stress
T3820 145-155 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T3821 145-177 http://purl.obolibrary.org/obo/GO_0030888 denotes regulation of cell proliferation
T3822 145-177 http://purl.obolibrary.org/obo/GO_0051140 denotes regulation of cell proliferation
T3823 145-177 http://purl.obolibrary.org/obo/GO_0060251 denotes regulation of cell proliferation
T3824 145-177 http://purl.obolibrary.org/obo/GO_0070666 denotes regulation of cell proliferation
T3825 145-177 http://purl.obolibrary.org/obo/GO_1904073 denotes regulation of cell proliferation
T3826 145-177 http://purl.obolibrary.org/obo/GO_1904697 denotes regulation of cell proliferation
T3827 145-177 http://purl.obolibrary.org/obo/GO_1904441 denotes regulation of cell proliferation
T3828 159-177 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T3829 453-459 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T3830 1544-1572 http://purl.obolibrary.org/obo/GO_1902883 denotes response to oxidative stress
T3831 1544-1572 http://purl.obolibrary.org/obo/GO_0006979 denotes response to oxidative stress
T3832 1544-1572 http://purl.obolibrary.org/obo/GO_0097468 denotes response to oxidative stress

GO-CC

Id Subject Object Predicate Lexical cue
T4613 51-56 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4614 341-346 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4615 492-497 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4616 565-570 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4617 657-662 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4618 745-750 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4619 829-834 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4620 883-888 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4621 1008-1013 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4622 1258-1263 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4623 1698-1703 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4624 2052-2056 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4625 1825-1827 http://purl.obolibrary.org/obo/GO_0005783 denotes ER

sentences

Id Subject Object Predicate Lexical cue
T3809 98-210 Sentence denotes PKD enzymes have previously been linked to the regulation of cell proliferation and survival (reviewed in [20]).
T3810 211-374 Sentence denotes To investigate the effect that loss of PKD kinases had on B cell survival and/or proliferation we cultured wild-type and PKD-null cells in the presence (PKD1/3−/−:
T3811 375-460 Sentence denotes Flag-PKD3+ve) or absence (PKD1/3−/−) of doxycycline and monitored exponential growth.
T3812 461-614 Sentence denotes As shown in Fig. 2A, PKD1/3−/− cells proliferated exponentially and re-expression of Flag-PKD3 in these cells had no impact on the rate of proliferation.
T3813 615-768 Sentence denotes Furthermore, the viability of PKD1/3−/− B cells during routine culturing was not significantly different from that of wild-type B cells (data not shown).
T3814 769-1156 Sentence denotes It was noted that the population doubling time of PKD1/3−/− cells was slightly slower than that of wild type DT40 cells (12.7 ± 2.8 h versus 10.2 ± 0.4 h) but the failure of PKD3 re-expression to modify the proliferation rate of PKD1/3−/− cells suggests that these small differences were most likely the result of clonal variation and were not caused specifically by loss of PKD enzymes.
T3815 1157-1264 Sentence denotes Thus, PKD family enzymes are not essential for regulating basal survival and proliferation of DT40 B cells.
T3816 1265-1456 Sentence denotes PKD enzymes, specifically PKD1 and PKD2, have previously been linked to a protective role against oxidative stress-induced injury in 3T3 fibroblast, HeLa and epithelial cell lines [17,30–32].
T3817 1457-1598 Sentence denotes We therefore addressed the role of PKD family kinases in regulating B cell survival in response to oxidative stress and other stress stimuli.
T3818 1599-1987 Sentence denotes As shown in Fig. 2B, loss of PKD1/3 expression had no significant impact on the survival of DT40 B cells in response to mitochondrial stress stimuli (H2O2 or serum deprivation); DNA damaging agents (etoposide or doxorubicin); ER pathway stress due to calcium overload (thapsigargin) or following prolonged treatment with phorbol esters or Trichostatin A, an inhibitor of class I/II HDACs.
T3819 1988-2117 Sentence denotes Thus, PKD kinases do not play an essential role in regulating B cell survival in response to a range of different stress stimuli.
T50 0-97 Sentence denotes 3.2 Cellular proliferation and survival in DT40 B cells lacking expression of PKD family kinases
T51 98-210 Sentence denotes PKD enzymes have previously been linked to the regulation of cell proliferation and survival (reviewed in [20]).
T52 211-374 Sentence denotes To investigate the effect that loss of PKD kinases had on B cell survival and/or proliferation we cultured wild-type and PKD-null cells in the presence (PKD1/3−/−:
T53 375-460 Sentence denotes Flag-PKD3+ve) or absence (PKD1/3−/−) of doxycycline and monitored exponential growth.
T54 461-614 Sentence denotes As shown in Fig. 2A, PKD1/3−/− cells proliferated exponentially and re-expression of Flag-PKD3 in these cells had no impact on the rate of proliferation.
T55 615-768 Sentence denotes Furthermore, the viability of PKD1/3−/− B cells during routine culturing was not significantly different from that of wild-type B cells (data not shown).
T56 769-1156 Sentence denotes It was noted that the population doubling time of PKD1/3−/− cells was slightly slower than that of wild type DT40 cells (12.7 ± 2.8 h versus 10.2 ± 0.4 h) but the failure of PKD3 re-expression to modify the proliferation rate of PKD1/3−/− cells suggests that these small differences were most likely the result of clonal variation and were not caused specifically by loss of PKD enzymes.
T57 1157-1264 Sentence denotes Thus, PKD family enzymes are not essential for regulating basal survival and proliferation of DT40 B cells.
T58 1265-1456 Sentence denotes PKD enzymes, specifically PKD1 and PKD2, have previously been linked to a protective role against oxidative stress-induced injury in 3T3 fibroblast, HeLa and epithelial cell lines [17,30–32].
T59 1457-1598 Sentence denotes We therefore addressed the role of PKD family kinases in regulating B cell survival in response to oxidative stress and other stress stimuli.
T60 1599-1987 Sentence denotes As shown in Fig. 2B, loss of PKD1/3 expression had no significant impact on the survival of DT40 B cells in response to mitochondrial stress stimuli (H2O2 or serum deprivation); DNA damaging agents (etoposide or doxorubicin); ER pathway stress due to calcium overload (thapsigargin) or following prolonged treatment with phorbol esters or Trichostatin A, an inhibitor of class I/II HDACs.
T61 1988-2117 Sentence denotes Thus, PKD kinases do not play an essential role in regulating B cell survival in response to a range of different stress stimuli.

ICD10

Id Subject Object Predicate Lexical cue
T4612 1388-1394 http://purl.bioontology.org/ontology/ICD10/T14.9 denotes injury

events-check-again

Id Subject Object Predicate Lexical cue
T4751 364-368 Protein denotes PKD1
T4752 369-370 Protein denotes 3
T4753 380-384 Protein denotes PKD3
T4754 401-405 Protein denotes PKD1
T4755 406-407 Protein denotes 3
T4756 482-486 Protein denotes PKD1
T4757 487-488 Protein denotes 3
T4758 529-542 Gene_expression denotes re-expression
T4759 551-555 Protein denotes PKD3
T4760 645-649 Protein denotes PKD1
T4761 650-651 Protein denotes 3
T4762 819-823 Protein denotes PKD1
T4763 824-825 Protein denotes 3
T4764 943-947 Protein denotes PKD3
T4765 948-961 Gene_expression denotes re-expression
T4766 998-1002 Protein denotes PKD1
T4767 1003-1004 Protein denotes 3
T4768 1291-1295 Protein denotes PKD1
T4769 1300-1304 Protein denotes PKD2
T4770 1620-1624 Negative_regulation denotes loss
T4771 1620-1624 Negative_regulation denotes loss
T4772 1628-1632 Protein denotes PKD1
T4773 1633-1634 Protein denotes 3
T4774 1635-1645 Gene_expression denotes expression
T4775 1635-1645 Gene_expression denotes expression
R3843 T4759 T4758 themeOf PKD3,re-expression
R3844 T4764 T4765 themeOf PKD3,re-expression
R3845 T4772 T4774 themeOf PKD1,expression
R3846 T4773 T4775 themeOf 3,expression
R3847 T4774 T4771 themeOf expression,loss
R3848 T4775 T4770 themeOf expression,loss

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T4793 645-649 Protein denotes PKD1
T4794 819-823 Protein denotes PKD1
T4795 943-947 Protein denotes PKD3
T4796 998-1002 Protein denotes PKD1
T4797 1144-1155 Protein denotes PKD enzymes
T4798 948-961 Gene_expression denotes re-expression
T4799 1136-1140 Negative_regulation denotes loss
T4800 1163-1181 Protein denotes PKD family enzymes
T4801 1251-1257 Protein denotes DT40 B
T4802 1265-1276 Protein denotes PKD enzymes
T4803 1291-1295 Protein denotes PKD1
T4804 1300-1304 Protein denotes PKD2
T4805 1492-1510 Protein denotes PKD family kinases
T4806 1611-1614 Protein denotes Fig
T4807 1628-1632 Protein denotes PKD1
T4808 1633-1634 Protein denotes 3
T4809 1691-1697 Protein denotes DT40 B
T4810 1976-1986 Protein denotes I/II HDACs
T4811 1635-1645 Gene_expression denotes expression
T4812 1635-1645 Gene_expression denotes expression
T4813 1957-1966 Negative_regulation denotes inhibitor
T4814 1620-1624 Negative_regulation denotes loss
T4815 1620-1624 Negative_regulation denotes loss
T4816 1994-2005 Protein denotes PKD kinases
T4776 79-89 Protein denotes PKD family
T4777 65-75 Gene_expression denotes expression
T4778 57-64 Negative_regulation denotes lacking
T4779 98-101 Protein denotes PKD
T4780 250-261 Protein denotes PKD kinases
T4781 332-335 Protein denotes PKD
T4782 364-368 Protein denotes PKD1
T4783 375-379 Protein denotes Flag
T4784 380-384 Protein denotes PKD3
T4785 401-405 Protein denotes PKD1
T4786 242-246 Negative_regulation denotes loss
T4787 473-476 Protein denotes Fig
T4788 482-486 Protein denotes PKD1
T4789 546-550 Protein denotes Flag
T4790 551-555 Protein denotes PKD3
T4791 529-542 Gene_expression denotes re-expression
T4792 529-542 Gene_expression denotes re-expression
R3849 T4776 T4777 themeOf PKD family,expression
R3850 T4777 T4778 themeOf expression,lacking
R3851 T4780 T4786 themeOf PKD kinases,loss
R3852 T4789 T4791 themeOf Flag,re-expression
R3853 T4790 T4792 themeOf PKD3,re-expression
R3854 T4795 T4798 themeOf PKD3,re-expression
R3855 T4797 T4799 themeOf PKD enzymes,loss
R3856 T4807 T4811 themeOf PKD1,expression
R3857 T4808 T4812 themeOf 3,expression
R3858 T4810 T4813 themeOf I/II HDACs,inhibitor
R3859 T4811 T4814 themeOf expression,loss
R3860 T4812 T4815 themeOf expression,loss

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue
T3783 364-368 Protein denotes PKD1
T3784 369-370 Protein denotes 3
T3785 380-384 Protein denotes PKD3
T3786 401-405 Protein denotes PKD1
T3787 406-407 Protein denotes 3
T3788 482-486 Protein denotes PKD1
T3789 487-488 Protein denotes 3
T3790 529-542 Gene_expression denotes re-expression
T3791 551-555 Protein denotes PKD3
T3792 645-649 Protein denotes PKD1
T3793 650-651 Protein denotes 3
T3794 819-823 Protein denotes PKD1
T3795 824-825 Protein denotes 3
T3796 943-947 Protein denotes PKD3
T3797 948-961 Gene_expression denotes re-expression
T3798 998-1002 Protein denotes PKD1
T3799 1003-1004 Protein denotes 3
T3800 1291-1295 Protein denotes PKD1
T3801 1300-1304 Protein denotes PKD2
T3802 1620-1624 Negative_regulation denotes loss
T3803 1620-1624 Negative_regulation denotes loss
T3804 1628-1632 Protein denotes PKD1
T3805 1633-1634 Protein denotes 3
T3806 1635-1645 Gene_expression denotes expression
T3807 1635-1645 Gene_expression denotes expression
R3050 T3791 T3790 themeOf PKD3,re-expression
R3051 T3796 T3797 themeOf PKD3,re-expression
R3052 T3804 T3806 themeOf PKD1,expression
R3053 T3805 T3807 themeOf 3,expression
R3054 T3806 T3803 themeOf expression,loss
R3055 T3807 T3802 themeOf expression,loss

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T4193 364-368 P98161 denotes PKD1
T4194 380-384 Q99853 denotes PKD3
T4195 401-405 P98161 denotes PKD1
T4196 482-486 P98161 denotes PKD1
T4197 551-555 Q99853 denotes PKD3
T4198 645-649 P98161 denotes PKD1
T4199 819-823 P98161 denotes PKD1
T4200 943-947 Q99853 denotes PKD3
T4201 998-1002 P98161 denotes PKD1
T4202 1291-1295 P98161 denotes PKD1
T4203 1628-1632 P98161 denotes PKD1
T4204 1825-1827 P03372 denotes ER

test2

Id Subject Object Predicate Lexical cue
T3755 364-368 Protein denotes PKD1
T3756 369-370 Protein denotes 3
T3757 380-384 Protein denotes PKD3
T3758 401-405 Protein denotes PKD1
T3759 406-407 Protein denotes 3
T3760 482-486 Protein denotes PKD1
T3761 487-488 Protein denotes 3
T3762 529-531 Positive_regulation denotes re
T3763 531-532 Gene_expression denotes -
T3764 532-542 Gene_expression denotes expression
T3765 551-555 Protein denotes PKD3
T3766 645-649 Protein denotes PKD1
T3767 650-651 Protein denotes 3
T3768 819-823 Protein denotes PKD1
T3769 824-825 Protein denotes 3
T3770 943-947 Protein denotes PKD3
T3771 948-951 Gene_expression denotes re-
T3772 951-961 Gene_expression denotes expression
T3773 998-1002 Protein denotes PKD1
T3774 1003-1004 Protein denotes 3
T3775 1291-1295 Protein denotes PKD1
T3776 1300-1304 Protein denotes PKD2
T3777 1620-1624 Negative_regulation denotes loss
T3778 1628-1632 Protein denotes PKD1
T3779 1633-1634 Protein denotes 3
T3780 1635-1645 Gene_expression denotes expression
T3781 1957-1966 Negative_regulation denotes inhibitor
R3047 T3778 T3780 themeOf PKD1,expression
R3048 T3779 T3780 themeOf 3,expression
R3049 T3780 T3777 themeOf expression,loss