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PMC:1942070 / 635-1057 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T138 0-9 CD denotes 1569–1577
T139 9-10 -RRB- denotes ]
T140 12-14 PRP denotes We
T141 15-18 RB denotes now
T142 19-23 VB denotes show
T143 24-28 IN denotes that
T144 29-33 NN denotes PKDs
T145 34-37 VB denotes are
T146 38-42 RB denotes also
T147 43-51 VB denotes required
T148 52-54 TO denotes to
T149 55-63 VB denotes regulate
T150 64-69 NN denotes HSP27
T151 70-85 NN denotes phosphorylation
T152 86-88 IN denotes in
T153 89-93 NN denotes DT40
T154 94-101 NN denotes B-cells
T155 103-110 RB denotes However
T156 110-111 -COMMA- denotes ,
T157 112-114 IN denotes in
T158 115-123 NN denotes contrast
T159 124-126 TO denotes to
T160 127-135 JJ denotes previous
T161 136-148 NN denotes observations
T162 149-151 IN denotes in
T163 152-157 JJ denotes other
T164 158-162 NN denotes cell
T165 163-168 NN denotes types
T166 168-169 -COMMA- denotes ,
T167 170-173 NN denotes PKD
T168 174-181 NN denotes enzymes
T169 182-184 VB denotes do
T170 185-188 RB denotes not
T171 189-197 VB denotes regulate
T172 198-203 JJ denotes basic
T173 204-212 JJ denotes cellular
T174 213-222 NN denotes processes
T175 223-227 JJ denotes such
T176 228-230 IN denotes as
T177 231-244 NN denotes proliferation
T178 245-247 CC denotes or
T179 248-256 NN denotes survival
T180 257-266 NN denotes responses
T181 266-267 -COMMA- denotes ,
T182 268-271 CC denotes nor
T183 272-276 NN denotes NFκB
T184 277-292 JJ denotes transcriptional
T185 293-301 NN denotes activity
T186 302-312 RB denotes downstream
T187 313-315 IN denotes of
T188 316-319 DT denotes the
T189 320-321 NN denotes B
T190 322-326 NN denotes cell
T191 327-334 NN denotes antigen
T192 335-343 NN denotes receptor
T193 345-349 RB denotes Thus
T194 349-350 -COMMA- denotes ,
T195 351-355 NN denotes PKDs
T196 356-360 VB denotes have
T197 361-362 DT denotes a
T198 363-372 JJ denotes selective
T199 373-377 NN denotes role
T200 378-380 IN denotes in
T201 381-385 NN denotes DT40
T202 386-392 NN denotes B-cell
T203 393-400 NN denotes biology
T532 0-422 NN denotes 1569–1577]. We now show that PKDs are also required to regulate HSP27 phosphorylation in DT40 B-cells. However, in contrast to previous observations in other cell types, PKD enzymes do not regulate basic cellular processes such as proliferation or survival responses, nor NFκB transcriptional activity downstream of the B cell antigen receptor. Thus, PKDs have a selective role in DT40 B-cell biology. 1 Introduction The
R110 T138 T139 arg1Of 1569–1577,]
R111 T140 T142 arg1Of We,show
R112 T142 T141 arg1Of show,now
R113 T144 T145 arg1Of PKDs,are
R114 T144 T147 arg2Of PKDs,required
R115 T144 T149 arg1Of PKDs,regulate
R116 T147 T142 arg2Of required,show
R117 T147 T143 arg1Of required,that
R118 T147 T145 arg2Of required,are
R119 T147 T146 arg1Of required,also
R120 T149 T147 arg3Of regulate,required
R121 T149 T148 arg1Of regulate,to
R122 T149 T152 arg1Of regulate,in
R123 T151 T149 arg2Of phosphorylation,regulate
R124 T151 T150 arg1Of phosphorylation,HSP27
R125 T154 T152 arg2Of B-cells,in
R126 T154 T153 arg1Of B-cells,DT40
R127 T158 T157 arg2Of contrast,in
R128 T158 T159 arg1Of contrast,to
R129 T161 T159 arg2Of observations,to
R130 T161 T160 arg1Of observations,previous
R131 T161 T162 arg1Of observations,in
R132 T165 T162 arg2Of types,in
R133 T165 T163 arg1Of types,other
R134 T165 T164 arg1Of types,cell
R135 T168 T167 arg1Of enzymes,PKD
R136 T168 T169 arg1Of enzymes,do
R137 T168 T171 arg1Of enzymes,regulate
R138 T171 T155 arg1Of regulate,However
R139 T171 T156 arg1Of regulate,","
R140 T171 T157 arg1Of regulate,in
R141 T171 T166 arg1Of regulate,","
R142 T171 T169 arg2Of regulate,do
R143 T171 T170 arg1Of regulate,not
R144 T174 T171 arg2Of processes,regulate
R145 T174 T172 arg1Of processes,basic
R146 T174 T173 arg1Of processes,cellular
R147 T174 T176 arg1Of processes,as
R148 T176 T175 arg1Of as,such
R149 T177 T178 arg1Of proliferation,or
R150 T178 T182 arg1Of or,nor
R151 T180 T178 arg2Of responses,or
R152 T180 T179 arg1Of responses,survival
R153 T182 T176 arg2Of nor,as
R154 T182 T181 arg1Of nor,","
R155 T185 T182 arg2Of activity,nor
R156 T185 T183 arg1Of activity,NFκB
R157 T185 T184 arg1Of activity,transcriptional
R158 T185 T186 arg1Of activity,downstream
R159 T186 T187 arg1Of downstream,of
R160 T192 T187 arg2Of receptor,of
R161 T192 T188 arg1Of receptor,the
R162 T192 T189 arg1Of receptor,B
R163 T192 T190 arg1Of receptor,cell
R164 T192 T191 arg1Of receptor,antigen
R165 T195 T196 arg1Of PKDs,have
R166 T196 T193 arg1Of have,Thus
R167 T196 T194 arg1Of have,","
R168 T196 T200 arg1Of have,in
R169 T199 T196 arg2Of role,have
R170 T199 T197 arg1Of role,a
R171 T199 T198 arg1Of role,selective
R172 T203 T200 arg2Of biology,in
R173 T203 T201 arg1Of biology,DT40
R174 T203 T202 arg1Of biology,B-cell

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T328 0-4 CD denotes 1569
T329 5-9 CD denotes 1577
T330 9-10 NNP denotes ]
T331 10-11 . denotes .
T332 12-14 PRP denotes We
T333 15-18 RB denotes now
T334 19-23 VBP denotes show
T335 24-28 IN denotes that
T336 29-33 NNS denotes PKDs
T337 34-37 VBP denotes are
T338 38-42 RB denotes also
T339 43-51 VBN denotes required
T340 52-54 TO denotes to
T341 55-63 VB denotes regulate
T342 64-69 NNP denotes HSP27
T343 70-85 NN denotes phosphorylation
T344 86-88 IN denotes in
T345 89-93 NNP denotes DT40
T346 94-101 NNPS denotes B-cells
T347 101-102 . denotes .
T348 103-110 RB denotes However
T349 110-111 , denotes ,
T350 112-114 IN denotes in
T351 115-123 NN denotes contrast
T352 124-126 TO denotes to
T353 127-135 JJ denotes previous
T354 136-148 NNS denotes observations
T355 149-151 IN denotes in
T356 152-157 JJ denotes other
T357 158-162 NN denotes cell
T358 163-168 NNS denotes types
T359 168-169 , denotes ,
T360 170-173 NNP denotes PKD
T361 174-181 VBZ denotes enzymes
T362 182-184 VB denotes do
T363 185-188 RB denotes not
T364 189-197 VB denotes regulate
T365 198-203 JJ denotes basic
T366 204-212 JJ denotes cellular
T367 213-222 NNS denotes processes
T368 223-227 JJ denotes such
T369 228-230 IN denotes as
T370 231-244 NN denotes proliferation
T371 245-247 CC denotes or
T372 248-256 NN denotes survival
T373 257-266 NNS denotes responses
T374 266-267 , denotes ,
T375 268-271 CC denotes nor
T376 272-276 NNP denotes NFκB
T377 277-292 JJ denotes transcriptional
T378 293-301 NN denotes activity
T379 302-312 JJ denotes downstream
T380 313-315 IN denotes of
T381 316-319 DT denotes the
T382 320-321 NNP denotes B
T383 322-326 NN denotes cell
T384 327-334 NN denotes antigen
T385 335-343 NN denotes receptor
T386 343-344 . denotes .
T387 345-349 RB denotes Thus
T388 349-350 , denotes ,
T389 351-355 NNS denotes PKDs
T390 356-360 VBP denotes have
T391 361-362 DT denotes a
T392 363-372 JJ denotes selective
T393 373-377 NN denotes role
T394 378-380 IN denotes in
T395 381-385 NNP denotes DT40
T396 386-392 NNP denotes B-cell
T397 393-400 NN denotes biology
T398 400-401 . denotes .
T1008 0-422 JJ denotes 1569–1577]. We now show that PKDs are also required to regulate HSP27 phosphorylation in DT40 B-cells. However, in contrast to previous observations in other cell types, PKD enzymes do not regulate basic cellular processes such as proliferation or survival responses, nor NFκB transcriptional activity downstream of the B cell antigen receptor. Thus, PKDs have a selective role in DT40 B-cell biology. 1 Introduction The
R293 T330 T330 ROOT ],]
R295 T332 T334 nsubj We,show
R296 T333 T334 advmod now,show
R297 T334 T334 ROOT show,show
R298 T335 T339 mark that,required
R299 T336 T339 nsubjpass PKDs,required
R300 T337 T339 auxpass are,required
R301 T338 T339 advmod also,required
R302 T339 T334 ccomp required,show
R303 T340 T341 aux to,regulate
R304 T341 T339 xcomp regulate,required
R305 T342 T343 compound HSP27,phosphorylation
R306 T343 T341 dobj phosphorylation,regulate
R307 T344 T343 prep in,phosphorylation
R308 T345 T346 compound DT40,B-cells
R309 T346 T344 pobj B-cells,in
R310 T347 T334 punct .,show
R311 T348 T364 advmod However,regulate
R312 T349 T364 punct ",",regulate
R313 T350 T364 prep in,regulate
R314 T351 T350 pobj contrast,in
R315 T352 T351 prep to,contrast
R316 T353 T354 amod previous,observations
R317 T354 T352 pobj observations,to
R318 T355 T354 prep in,observations
R319 T356 T358 amod other,types
R320 T357 T358 compound cell,types
R321 T358 T355 pobj types,in
R322 T359 T364 punct ",",regulate
R323 T360 T364 nsubj PKD,regulate
R324 T361 T364 nsubj enzymes,regulate
R325 T362 T364 aux do,regulate
R326 T363 T364 neg not,regulate
R327 T364 T364 ROOT regulate,regulate
R328 T365 T367 amod basic,processes
R329 T366 T367 amod cellular,processes
R330 T367 T364 dobj processes,regulate
R331 T368 T369 amod such,as
R332 T369 T367 prep as,processes
R333 T370 T369 pobj proliferation,as
R334 T371 T370 cc or,proliferation
R335 T372 T370 conj survival,proliferation
R336 T373 T370 conj responses,proliferation
R337 T374 T373 punct ",",responses
R338 T375 T364 cc nor,regulate
R339 T376 T378 nmod NFκB,activity
R340 T377 T378 amod transcriptional,activity
R341 T378 T364 conj activity,regulate
R342 T379 T378 amod downstream,activity
R343 T380 T379 prep of,downstream
R344 T381 T385 det the,receptor
R345 T382 T384 compound B,antigen
R346 T383 T384 compound cell,antigen
R347 T384 T385 compound antigen,receptor
R348 T385 T380 pobj receptor,of
R349 T386 T364 punct .,regulate
R350 T387 T390 advmod Thus,have
R351 T388 T390 punct ",",have
R352 T389 T390 nsubj PKDs,have
R353 T390 T390 ROOT have,have
R354 T391 T393 det a,role
R355 T392 T393 amod selective,role
R356 T393 T390 dobj role,have
R357 T394 T393 prep in,role
R358 T395 T396 compound DT40,B-cell
R359 T396 T397 compound B-cell,biology
R360 T397 T394 pobj biology,in
R361 T398 T390 punct .,have

GO-BP

Id Subject Object Predicate Lexical cue
T22 70-85 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T23 204-212 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T24 204-222 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T25 277-292 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional

GO-CC

Id Subject Object Predicate Lexical cue
T401 96-101 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T402 158-162 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T403 322-326 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T404 388-392 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T405 204-222 http://purl.obolibrary.org/obo/GO_0042995 denotes cellular processes

sentences

Id Subject Object Predicate Lexical cue
T18 12-102 Sentence denotes We now show that PKDs are also required to regulate HSP27 phosphorylation in DT40 B-cells.
T19 103-344 Sentence denotes However, in contrast to previous observations in other cell types, PKD enzymes do not regulate basic cellular processes such as proliferation or survival responses, nor NFκB transcriptional activity downstream of the B cell antigen receptor.
T20 345-401 Sentence denotes Thus, PKDs have a selective role in DT40 B-cell biology.
T8 12-102 Sentence denotes We now show that PKDs are also required to regulate HSP27 phosphorylation in DT40 B-cells.
T9 103-344 Sentence denotes However, in contrast to previous observations in other cell types, PKD enzymes do not regulate basic cellular processes such as proliferation or survival responses, nor NFκB transcriptional activity downstream of the B cell antigen receptor.
T10 345-401 Sentence denotes Thus, PKDs have a selective role in DT40 B-cell biology.
T11 403-418 Sentence denotes 1 Introduction

events-check-again

Id Subject Object Predicate Lexical cue
T425 43-51 Positive_regulation denotes required
T426 55-63 Regulation denotes regulate
T427 64-69 Protein denotes HSP27
T428 70-85 Phosphorylation denotes phosphorylation
R410 T426 T425 themeOf regulate,required
R411 T427 T428 themeOf HSP27,phosphorylation
R412 T428 T426 themeOf phosphorylation,regulate

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T440 29-33 Protein denotes PKDs
T441 64-69 Protein denotes HSP27
T442 70-85 Phosphorylation denotes phosphorylation
T443 55-63 Regulation denotes regulate
T444 43-51 Positive_regulation denotes required
T445 170-181 Protein denotes PKD enzymes
T446 272-276 Protein denotes NFκB
T447 320-343 Protein denotes B cell antigen receptor
T448 189-197 Regulation denotes regulate
T449 351-355 Protein denotes PKDs
R364 T440 T443 causeOf PKDs,regulate
R365 T440 T444 causeOf PKDs,required
R366 T441 T442 themeOf HSP27,phosphorylation
R367 T442 T443 themeOf phosphorylation,regulate
R368 T443 T444 themeOf regulate,required
R369 T445 T448 causeOf PKD enzymes,regulate
R370 T447 T448 themeOf B cell antigen receptor,regulate

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue
T10 43-51 Positive_regulation denotes required
T11 55-63 Regulation denotes regulate
T12 64-69 Protein denotes HSP27
T13 70-85 Phosphorylation denotes phosphorylation
R371 T11 T10 themeOf regulate,required
R372 T12 T13 themeOf HSP27,phosphorylation
R373 T13 T11 themeOf phosphorylation,regulate

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T204 64-69 P04792 denotes HSP27

test2

Id Subject Object Predicate Lexical cue
T5 43-51 Positive_regulation denotes required
T6 55-63 Regulation denotes regulate
T7 64-69 Protein denotes HSP27
T8 70-85 Phosphorylation denotes phosphorylation
R4 T6 T5 themeOf regulate,required
R5 T7 T8 themeOf HSP27,phosphorylation
R6 T8 T6 themeOf phosphorylation,regulate