PMC:1942070 / 0-281 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1942070","sourcedb":"PMC","sourceid":"1942070","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1942070","text":"Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFκB activity in vertebrate B-cells \n\nAbstract\nTo investigate the importance of protein kinase D (PKD) enzymes we generated a PKD-null DT40 B-lymphocyte cell line. Previously we hav","divisions":[{"label":"Title","span":{"begin":0,"end":136}}],"tracks":[{"project":"pmc-enju-pas","denotations":[{"id":"T49","span":{"begin":180,"end":187},"obj":"NN"},{"id":"T50","span":{"begin":188,"end":194},"obj":"NN"},{"id":"T51","span":{"begin":195,"end":196},"obj":"NN"},{"id":"T52","span":{"begin":197,"end":198},"obj":"-LRB-"},{"id":"T53","span":{"begin":198,"end":201},"obj":"NN"},{"id":"T54","span":{"begin":201,"end":202},"obj":"-RRB-"},{"id":"T55","span":{"begin":203,"end":210},"obj":"NN"},{"id":"T56","span":{"begin":211,"end":213},"obj":"PRP"},{"id":"T57","span":{"begin":214,"end":223},"obj":"VB"},{"id":"T58","span":{"begin":224,"end":225},"obj":"DT"},{"id":"T59","span":{"begin":226,"end":234},"obj":"JJ"},{"id":"T60","span":{"begin":235,"end":239},"obj":"NN"},{"id":"T61","span":{"begin":240,"end":252},"obj":"NN"},{"id":"T62","span":{"begin":253,"end":257},"obj":"NN"},{"id":"T63","span":{"begin":258,"end":262},"obj":"NN"},{"id":"T64","span":{"begin":264,"end":274},"obj":"RB"},{"id":"T65","span":{"begin":275,"end":277},"obj":"PRP"},{"id":"T26","span":{"begin":0,"end":7},"obj":"NN"},{"id":"T27","span":{"begin":8,"end":14},"obj":"NN"},{"id":"T28","span":{"begin":15,"end":16},"obj":"NN"},{"id":"T29","span":{"begin":17,"end":24},"obj":"NN"},{"id":"T30","span":{"begin":25,"end":28},"obj":"VB"},{"id":"T31","span":{"begin":29,"end":40},"obj":"JJ"},{"id":"T32","span":{"begin":41,"end":44},"obj":"IN"},{"id":"T33","span":{"begin":45,"end":58},"obj":"NN"},{"id":"T34","span":{"begin":58,"end":59},"obj":"-COMMA-"},{"id":"T35","span":{"begin":60,"end":68},"obj":"NN"},{"id":"T36","span":{"begin":69,"end":72},"obj":"CC"},{"id":"T37","span":{"begin":73,"end":80},"obj":"NN"},{"id":"T38","span":{"begin":81,"end":99},"obj":"JJ"},{"id":"T39","span":{"begin":100,"end":104},"obj":"NN"},{"id":"T40","span":{"begin":105,"end":113},"obj":"NN"},{"id":"T41","span":{"begin":114,"end":116},"obj":"IN"},{"id":"T42","span":{"begin":117,"end":127},"obj":"NN"},{"id":"T43","span":{"begin":128,"end":135},"obj":"NN"},{"id":"T44","span":{"begin":147,"end":149},"obj":"TO"},{"id":"T45","span":{"begin":150,"end":161},"obj":"VB"},{"id":"T46","span":{"begin":162,"end":165},"obj":"DT"},{"id":"T47","span":{"begin":166,"end":176},"obj":"NN"},{"id":"T48","span":{"begin":177,"end":179},"obj":"IN"}],"relations":[{"id":"R9","pred":"arg1Of","subj":"T51","obj":"T52"},{"id":"R10","pred":"arg2Of","subj":"T53","obj":"T52"},{"id":"R11","pred":"arg3Of","subj":"T54","obj":"T52"},{"id":"R15","pred":"arg1Of","subj":"T56","obj":"T57"},{"id":"R17","pred":"arg2Of","subj":"T63","obj":"T57"},{"id":"R18","pred":"arg1Of","subj":"T63","obj":"T58"},{"id":"R19","pred":"arg1Of","subj":"T63","obj":"T59"},{"id":"R20","pred":"arg1Of","subj":"T63","obj":"T60"},{"id":"R21","pred":"arg1Of","subj":"T63","obj":"T61"},{"id":"R22","pred":"arg1Of","subj":"T63","obj":"T62"},{"id":"R7","pred":"arg1Of","subj":"T51","obj":"T49"},{"id":"R8","pred":"arg1Of","subj":"T51","obj":"T50"},{"id":"R12","pred":"arg2Of","subj":"T55","obj":"T48"},{"id":"R13","pred":"arg1Of","subj":"T55","obj":"T51"},{"id":"R14","pred":"arg1Of","subj":"T56","obj":"T45"},{"id":"R16","pred":"modOf","subj":"T57","obj":"T44"},{"id":"R374","pred":"arg1Of","subj":"T29","obj":"T26"},{"id":"R375","pred":"arg1Of","subj":"T29","obj":"T27"},{"id":"R376","pred":"arg1Of","subj":"T29","obj":"T28"},{"id":"R377","pred":"arg1Of","subj":"T29","obj":"T30"},{"id":"R378","pred":"arg1Of","subj":"T29","obj":"T31"},{"id":"R379","pred":"arg2Of","subj":"T31","obj":"T30"},{"id":"R380","pred":"arg1Of","subj":"T31","obj":"T32"},{"id":"R381","pred":"arg1Of","subj":"T33","obj":"T34"},{"id":"R382","pred":"arg1Of","subj":"T34","obj":"T36"},{"id":"R383","pred":"arg2Of","subj":"T35","obj":"T34"},{"id":"R384","pred":"arg2Of","subj":"T36","obj":"T32"},{"id":"R385","pred":"arg1Of","subj":"T36","obj":"T41"},{"id":"R386","pred":"arg2Of","subj":"T40","obj":"T36"},{"id":"R387","pred":"arg1Of","subj":"T40","obj":"T37"},{"id":"R388","pred":"arg1Of","subj":"T40","obj":"T38"},{"id":"R389","pred":"arg1Of","subj":"T40","obj":"T39"},{"id":"R390","pred":"arg2Of","subj":"T43","obj":"T41"},{"id":"R391","pred":"arg1Of","subj":"T43","obj":"T42"},{"id":"R392","pred":"arg1Of","subj":"T45","obj":"T44"},{"id":"R393","pred":"arg2Of","subj":"T47","obj":"T45"},{"id":"R394","pred":"arg1Of","subj":"T47","obj":"T46"},{"id":"R395","pred":"arg1Of","subj":"T47","obj":"T48"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"attributes":[{"subj":"T49","pred":"source","obj":"pmc-enju-pas"},{"subj":"T50","pred":"source","obj":"pmc-enju-pas"},{"subj":"T51","pred":"source","obj":"pmc-enju-pas"},{"subj":"T52","pred":"source","obj":"pmc-enju-pas"},{"subj":"T53","pred":"source","obj":"pmc-enju-pas"},{"subj":"T54","pred":"source","obj":"pmc-enju-pas"},{"subj":"T55","pred":"source","obj":"pmc-enju-pas"},{"subj":"T56","pred":"source","obj":"pmc-enju-pas"},{"subj":"T57","pred":"source","obj":"pmc-enju-pas"},{"subj":"T58","pred":"source","obj":"pmc-enju-pas"},{"subj":"T59","pred":"source","obj":"pmc-enju-pas"},{"subj":"T60","pred":"source","obj":"pmc-enju-pas"},{"subj":"T61","pred":"source","obj":"pmc-enju-pas"},{"subj":"T62","pred":"source","obj":"pmc-enju-pas"},{"subj":"T63","pred":"source","obj":"pmc-enju-pas"},{"subj":"T64","pred":"source","obj":"pmc-enju-pas"},{"subj":"T65","pred":"source","obj":"pmc-enju-pas"},{"subj":"T26","pred":"source","obj":"pmc-enju-pas"},{"subj":"T27","pred":"source","obj":"pmc-enju-pas"},{"subj":"T28","pred":"source","obj":"pmc-enju-pas"},{"subj":"T29","pred":"source","obj":"pmc-enju-pas"},{"subj":"T30","pred":"source","obj":"pmc-enju-pas"},{"subj":"T31","pred":"source","obj":"pmc-enju-pas"},{"subj":"T32","pred":"source","obj":"pmc-enju-pas"},{"subj":"T33","pred":"source","obj":"pmc-enju-pas"},{"subj":"T34","pred":"source","obj":"pmc-enju-pas"},{"subj":"T35","pred":"source","obj":"pmc-enju-pas"},{"subj":"T36","pred":"source","obj":"pmc-enju-pas"},{"subj":"T37","pred":"source","obj":"pmc-enju-pas"},{"subj":"T38","pred":"source","obj":"pmc-enju-pas"},{"subj":"T39","pred":"source","obj":"pmc-enju-pas"},{"subj":"T40","pred":"source","obj":"pmc-enju-pas"},{"subj":"T41","pred":"source","obj":"pmc-enju-pas"},{"subj":"T42","pred":"source","obj":"pmc-enju-pas"},{"subj":"T43","pred":"source","obj":"pmc-enju-pas"},{"subj":"T44","pred":"source","obj":"pmc-enju-pas"},{"subj":"T45","pred":"source","obj":"pmc-enju-pas"},{"subj":"T46","pred":"source","obj":"pmc-enju-pas"},{"subj":"T47","pred":"source","obj":"pmc-enju-pas"},{"subj":"T48","pred":"source","obj":"pmc-enju-pas"}]},{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T212","span":{"begin":0,"end":7},"obj":"NN"},{"id":"T213","span":{"begin":8,"end":14},"obj":"NN"},{"id":"T214","span":{"begin":15,"end":16},"obj":"NNP"},{"id":"T215","span":{"begin":17,"end":24},"obj":"NNS"},{"id":"T216","span":{"begin":25,"end":28},"obj":"VBP"},{"id":"T217","span":{"begin":29,"end":40},"obj":"JJ"},{"id":"T218","span":{"begin":41,"end":44},"obj":"IN"},{"id":"T219","span":{"begin":45,"end":58},"obj":"NN"},{"id":"T220","span":{"begin":58,"end":59},"obj":","},{"id":"T221","span":{"begin":60,"end":68},"obj":"NN"},{"id":"T222","span":{"begin":69,"end":72},"obj":"CC"},{"id":"T223","span":{"begin":73,"end":80},"obj":"NN"},{"id":"T224","span":{"begin":81,"end":99},"obj":"JJ"},{"id":"T225","span":{"begin":100,"end":104},"obj":"NN"},{"id":"T226","span":{"begin":105,"end":113},"obj":"NN"},{"id":"T227","span":{"begin":114,"end":116},"obj":"IN"},{"id":"T228","span":{"begin":117,"end":127},"obj":"JJ"},{"id":"T229","span":{"begin":128,"end":135},"obj":"NNPS"},{"id":"T230","span":{"begin":147,"end":149},"obj":"TO"},{"id":"T231","span":{"begin":150,"end":161},"obj":"VB"},{"id":"T232","span":{"begin":162,"end":165},"obj":"DT"},{"id":"T233","span":{"begin":166,"end":176},"obj":"NN"},{"id":"T234","span":{"begin":177,"end":179},"obj":"IN"},{"id":"T235","span":{"begin":180,"end":187},"obj":"NN"},{"id":"T236","span":{"begin":188,"end":194},"obj":"NN"},{"id":"T237","span":{"begin":195,"end":196},"obj":"NNP"},{"id":"T238","span":{"begin":197,"end":198},"obj":"-LRB-"},{"id":"T239","span":{"begin":198,"end":201},"obj":"NNP"},{"id":"T240","span":{"begin":201,"end":202},"obj":"-RRB-"},{"id":"T241","span":{"begin":203,"end":210},"obj":"VBZ"},{"id":"T242","span":{"begin":211,"end":213},"obj":"PRP"},{"id":"T243","span":{"begin":214,"end":223},"obj":"VBD"},{"id":"T244","span":{"begin":224,"end":225},"obj":"DT"},{"id":"T245","span":{"begin":226,"end":234},"obj":"NNP"},{"id":"T246","span":{"begin":235,"end":239},"obj":"NNP"},{"id":"T247","span":{"begin":240,"end":252},"obj":"NNP"},{"id":"T248","span":{"begin":253,"end":257},"obj":"NN"},{"id":"T249","span":{"begin":258,"end":262},"obj":"NN"},{"id":"T250","span":{"begin":262,"end":263},"obj":"."},{"id":"T251","span":{"begin":264,"end":274},"obj":"RB"},{"id":"T252","span":{"begin":275,"end":277},"obj":"PRP"}],"relations":[{"id":"R204","pred":"dobj","subj":"T241","obj":"T231"},{"id":"R205","pred":"nsubj","subj":"T242","obj":"T243"},{"id":"R206","pred":"relcl","subj":"T243","obj":"T241"},{"id":"R207","pred":"det","subj":"T244","obj":"T249"},{"id":"R208","pred":"compound","subj":"T245","obj":"T249"},{"id":"R209","pred":"compound","subj":"T246","obj":"T247"},{"id":"R210","pred":"compound","subj":"T247","obj":"T249"},{"id":"R211","pred":"compound","subj":"T248","obj":"T249"},{"id":"R212","pred":"dobj","subj":"T249","obj":"T243"},{"id":"R213","pred":"punct","subj":"T250","obj":"T216"},{"id":"R175","pred":"compound","subj":"T212","obj":"T215"},{"id":"R176","pred":"compound","subj":"T213","obj":"T215"},{"id":"R177","pred":"compound","subj":"T214","obj":"T215"},{"id":"R178","pred":"nsubj","subj":"T215","obj":"T216"},{"id":"R179","pred":"ROOT","subj":"T216","obj":"T216"},{"id":"R180","pred":"acomp","subj":"T217","obj":"T216"},{"id":"R181","pred":"prep","subj":"T218","obj":"T217"},{"id":"R182","pred":"nmod","subj":"T219","obj":"T226"},{"id":"R183","pred":"punct","subj":"T220","obj":"T219"},{"id":"R184","pred":"conj","subj":"T221","obj":"T219"},{"id":"R185","pred":"cc","subj":"T222","obj":"T221"},{"id":"R186","pred":"conj","subj":"T223","obj":"T221"},{"id":"R187","pred":"amod","subj":"T224","obj":"T226"},{"id":"R188","pred":"compound","subj":"T225","obj":"T226"},{"id":"R189","pred":"pobj","subj":"T226","obj":"T218"},{"id":"R190","pred":"prep","subj":"T227","obj":"T226"},{"id":"R191","pred":"amod","subj":"T228","obj":"T229"},{"id":"R192","pred":"pobj","subj":"T229","obj":"T227"},{"id":"R193","pred":"aux","subj":"T230","obj":"T231"},{"id":"R194","pred":"advcl","subj":"T231","obj":"T216"},{"id":"R195","pred":"det","subj":"T232","obj":"T233"},{"id":"R196","pred":"dobj","subj":"T233","obj":"T231"},{"id":"R197","pred":"prep","subj":"T234","obj":"T233"},{"id":"R198","pred":"pobj","subj":"T235","obj":"T234"},{"id":"R199","pred":"compound","subj":"T236","obj":"T237"},{"id":"R200","pred":"appos","subj":"T237","obj":"T235"},{"id":"R201","pred":"punct","subj":"T238","obj":"T237"},{"id":"R202","pred":"appos","subj":"T239","obj":"T237"},{"id":"R203","pred":"punct","subj":"T240","obj":"T237"}],"attributes":[{"subj":"T212","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T213","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T214","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T215","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T216","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T217","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T218","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T219","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T220","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T221","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T222","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T223","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T224","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T225","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T226","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T227","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T228","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T229","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T230","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T231","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T232","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T233","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T234","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T235","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T236","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T237","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T238","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T239","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T240","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T241","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T242","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T243","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T244","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T245","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T246","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T247","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T248","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T249","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T250","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T251","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T252","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"}]},{"project":"UBERON-AE","denotations":[{"id":"T9","span":{"begin":117,"end":127},"obj":"http://purl.obolibrary.org/obo/UBERON_3010224"}],"attributes":[{"subj":"T9","pred":"source","obj":"UBERON-AE"}]},{"project":"GO-CC","denotations":[{"id":"T399","span":{"begin":130,"end":135},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T399","pred":"source","obj":"GO-CC"}]},{"project":"sentences","denotations":[{"id":"T14","span":{"begin":0,"end":135},"obj":"Sentence"},{"id":"T15","span":{"begin":147,"end":263},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":135},"obj":"Sentence"},{"id":"T2","span":{"begin":138,"end":146},"obj":"Sentence"},{"id":"T3","span":{"begin":147,"end":263},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T14","pred":"source","obj":"sentences"},{"subj":"T15","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"}]},{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T429","span":{"begin":0,"end":24},"obj":"Protein"},{"id":"T430","span":{"begin":100,"end":104},"obj":"Protein"},{"id":"T431","span":{"begin":81,"end":99},"obj":"Regulation"},{"id":"T432","span":{"begin":180,"end":196},"obj":"Protein"},{"id":"T433","span":{"begin":198,"end":201},"obj":"Protein"},{"id":"T434","span":{"begin":226,"end":229},"obj":"Protein"}],"relations":[{"id":"R362","pred":"themeOf","subj":"T430","obj":"T431"}],"attributes":[{"subj":"T429","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"},{"subj":"T430","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"},{"subj":"T431","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"},{"subj":"T432","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"},{"subj":"T433","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"},{"subj":"T434","pred":"source","obj":"bionlp-st-ge-2016-reference-tees"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"pmc-enju-pas","color":"#adec93","default":true},{"id":"bionlp-st-ge-2016-spacy-parsed","color":"#ec93c7"},{"id":"UBERON-AE","color":"#93e1ec"},{"id":"GO-CC","color":"#ecdd93"},{"id":"sentences","color":"#c393ec"},{"id":"bionlp-st-ge-2016-reference-tees","color":"#93eca9"}]}]}}