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PMC:1941754 / 4751-5677 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T988 0-3 DT denotes The
T989 14-24 NN denotes checkpoint
T990 4-13 NN denotes pachytene
T991 28-33 VBN denotes known
T992 25-27 VBZ denotes is
T993 34-36 TO denotes to
T994 37-44 VB denotes monitor
T995 45-48 CD denotes two
T996 49-56 NNS denotes aspects
T997 57-59 IN denotes of
T998 60-67 JJ denotes meiotic
T999 79-89 NN denotes metabolism
T1000 68-78 NN denotes chromosome
T1001 90-92 IN denotes in
T1002 93-95 NNP denotes S.
T1003 96-106 NNP denotes cerevisiae
T1004 107-110 CC denotes and
T1005 111-113 NNP denotes C.
T1006 114-121 NNP denotes elegans
T1007 121-123 : denotes :
T1008 123-124 -LRB- denotes (
T1009 124-125 LS denotes 1
T1010 131-137 NN denotes repair
T1011 125-126 -RRB- denotes )
T1012 127-130 NN denotes DSB
T1013 138-141 CC denotes and
T1014 142-143 -LRB- denotes (
T1015 143-144 LS denotes 2
T1016 157-165 NN denotes synapsis
T1017 144-145 -RRB- denotes )
T1018 146-156 NN denotes chromosome
T1019 166-167 -LRB- denotes [
T1020 169-171 CD denotes 12
T1021 167-168 CD denotes 2
T1022 168-169 , denotes ,
T1023 171-172 -RRB- denotes ]
T1024 172-173 . denotes .
T1025 173-435 sentence denotes In mice, both spermatocytes and oocytes harboring mutations that disrupt DSB repair (such as Dmc1, Msh5, and Atm) are efficiently eliminated in pachynema, but spermatocytes are much more sensitive to DSB repair–independent synapsis defects than oocytes [13–15].
T1026 174-176 IN denotes In
T1027 304-314 VBN denotes eliminated
T1028 177-181 NNS denotes mice
T1029 181-183 , denotes ,
T1030 183-187 CC denotes both
T1031 188-201 NNS denotes spermatocytes
T1032 202-205 CC denotes and
T1033 206-213 NNS denotes oocytes
T1034 214-223 VBG denotes harboring
T1035 224-233 NNS denotes mutations
T1036 234-238 WDT denotes that
T1037 239-246 VBP denotes disrupt
T1038 247-250 NN denotes DSB
T1039 251-257 NN denotes repair
T1040 258-259 -LRB- denotes (
T1041 259-263 JJ denotes such
T1042 264-266 IN denotes as
T1043 267-271 NN denotes Dmc1
T1044 271-273 , denotes ,
T1045 273-277 NN denotes Msh5
T1046 277-279 , denotes ,
T1047 279-282 CC denotes and
T1048 283-286 NN denotes Atm
T1049 286-287 -RRB- denotes )
T1050 288-291 VBP denotes are
T1051 292-303 RB denotes efficiently
T1052 315-317 IN denotes in
T1053 318-327 NN denotes pachynema
T1054 327-329 , denotes ,
T1055 329-332 CC denotes but
T1056 333-346 NNS denotes spermatocytes
T1057 347-350 VBP denotes are
T1058 351-355 RB denotes much
T1059 356-360 RBR denotes more
T1060 361-370 JJ denotes sensitive
T1061 371-373 IN denotes to
T1062 374-377 NN denotes DSB
T1063 406-413 NNS denotes defects
T1064 378-384 NN denotes repair
T1065 385-396 JJ denotes independent
T1066 384-385 HYPH denotes –
T1067 397-405 NN denotes synapsis
T1068 414-418 IN denotes than
T1069 419-426 NNS denotes oocytes
T1070 427-428 -LRB- denotes [
T1071 428-430 CD denotes 13
T1072 430-431 SYM denotes –
T1073 431-433 CD denotes 15
T1074 433-434 -RRB- denotes ]
T1075 434-435 . denotes .
T1076 435-786 sentence denotes However, because recombination is required for synapsis in mice (mutations in recombination genes such as Dmc1 cause extensive asynapsis [16]), it has remained formally uncertain whether there is a distinct pachytene checkpoint that responds to defects in meiotic recombination, and if so, whether it would be identical to that used in somatic cells.
T1077 436-443 RB denotes However
T1078 587-595 VBN denotes remained
T1079 443-445 , denotes ,
T1080 445-452 IN denotes because
T1081 470-478 VBN denotes required
T1082 453-466 NN denotes recombination
T1083 467-469 VBZ denotes is
T1084 479-482 IN denotes for
T1085 483-491 NN denotes synapsis
T1086 492-494 IN denotes in
T1087 495-499 NNS denotes mice
T1088 500-501 -LRB- denotes (
T1089 547-552 VBP denotes cause
T1090 501-510 NNS denotes mutations
T1091 511-513 IN denotes in
T1092 514-527 NN denotes recombination
T1093 528-533 NNS denotes genes
T1094 534-538 JJ denotes such
T1095 539-541 IN denotes as
T1096 542-546 NN denotes Dmc1
T1097 553-562 JJ denotes extensive
T1098 563-572 NN denotes asynapsis
T1099 573-574 -LRB- denotes [
T1100 574-576 CD denotes 16
T1101 576-577 -RRB- denotes ]
T1102 577-578 -RRB- denotes )
T1103 578-580 , denotes ,
T1104 580-582 PRP denotes it
T1105 583-586 VBZ denotes has
T1106 596-604 RB denotes formally
T1107 605-614 JJ denotes uncertain
T1108 615-622 IN denotes whether
T1109 629-631 VBZ denotes is
T1110 623-628 EX denotes there
T1111 632-633 DT denotes a
T1112 653-663 NN denotes checkpoint
T1113 634-642 JJ denotes distinct
T1114 643-652 NN denotes pachytene
T1115 664-668 WDT denotes that
T1116 669-677 VBZ denotes responds
T1117 678-680 IN denotes to
T1118 681-688 NNS denotes defects
T1119 689-691 IN denotes in
T1120 692-699 JJ denotes meiotic
T1121 700-713 NN denotes recombination
T1122 713-715 , denotes ,
T1123 715-718 CC denotes and
T1124 719-721 IN denotes if
T1125 722-724 RB denotes so
T1126 743-745 VB denotes be
T1127 724-726 , denotes ,
T1128 726-733 IN denotes whether
T1129 734-736 PRP denotes it
T1130 737-742 MD denotes would
T1131 746-755 JJ denotes identical
T1132 756-758 IN denotes to
T1133 759-763 DT denotes that
T1134 764-768 VBN denotes used
T1135 769-771 IN denotes in
T1136 772-779 JJ denotes somatic
T1137 780-785 NNS denotes cells
T1138 785-786 . denotes .
T1139 786-926 sentence denotes The mechanisms of putative pachytene checkpoint control remain unknown in mammals, since no mutations have been identified that abolish it.
T1140 787-790 DT denotes The
T1141 791-801 NNS denotes mechanisms
T1142 843-849 VBP denotes remain
T1143 802-804 IN denotes of
T1144 805-813 JJ denotes putative
T1145 835-842 NN denotes control
T1146 814-823 NN denotes pachytene
T1147 824-834 NN denotes checkpoint
T1148 850-857 JJ denotes unknown
T1149 858-860 IN denotes in
T1150 861-868 NNS denotes mammals
T1151 868-870 , denotes ,
T1152 870-875 IN denotes since
T1153 899-909 VBN denotes identified
T1154 876-878 DT denotes no
T1155 879-888 NNS denotes mutations
T1156 889-893 VBP denotes have
T1157 894-898 VBN denotes been
T1158 910-914 WDT denotes that
T1159 915-922 VBP denotes abolish
T1160 923-925 PRP denotes it
T1161 925-926 . denotes .
R680 T1124 T1125 mark if,so
R681 T1125 T1126 advcl so,be
R682 T1126 T1109 conj be,is
R683 T1127 T1126 punct ", ",be
R684 T1128 T1126 mark whether,be
R685 T1129 T1126 nsubj it,be
R686 T1130 T1126 aux would,be
R687 T1131 T1126 acomp identical,be
R688 T1132 T1131 prep to,identical
R689 T1133 T1132 pobj that,to
R690 T1134 T1133 acl used,that
R691 T1135 T1134 prep in,used
R692 T1136 T1137 amod somatic,cells
R693 T1137 T1135 pobj cells,in
R694 T1138 T1078 punct .,remained
R695 T1140 T1141 det The,mechanisms
R696 T1141 T1142 nsubj mechanisms,remain
R697 T1143 T1141 prep of,mechanisms
R698 T1144 T1145 amod putative,control
R699 T1145 T1143 pobj control,of
R700 T1146 T1147 compound pachytene,checkpoint
R701 T1147 T1145 compound checkpoint,control
R702 T1148 T1142 acomp unknown,remain
R703 T1149 T1142 prep in,remain
R704 T1150 T1149 pobj mammals,in
R705 T1151 T1142 punct ", ",remain
R706 T1152 T1153 mark since,identified
R707 T1153 T1142 advcl identified,remain
R708 T1154 T1155 det no,mutations
R709 T1155 T1153 nsubjpass mutations,identified
R710 T1156 T1153 aux have,identified
R711 T1157 T1153 auxpass been,identified
R712 T1158 T1159 dep that,abolish
R549 T988 T989 det The,checkpoint
R550 T989 T991 nsubjpass checkpoint,known
R551 T990 T989 compound pachytene,checkpoint
R552 T992 T991 auxpass is,known
R553 T993 T994 aux to,monitor
R554 T994 T991 xcomp monitor,known
R555 T995 T996 nummod two,aspects
R556 T996 T994 dobj aspects,monitor
R557 T997 T996 prep of,aspects
R558 T998 T999 amod meiotic,metabolism
R559 T999 T997 pobj metabolism,of
R560 T1000 T999 compound chromosome,metabolism
R561 T1001 T999 prep in,metabolism
R562 T1002 T1003 compound S.,cerevisiae
R563 T1003 T1001 pobj cerevisiae,in
R564 T1004 T1003 cc and,cerevisiae
R565 T1005 T1006 compound C.,elegans
R566 T1006 T1003 conj elegans,cerevisiae
R567 T1007 T996 punct : ,aspects
R568 T1008 T1009 punct (,1
R569 T1009 T1010 meta 1,repair
R570 T1010 T996 appos repair,aspects
R571 T1011 T1009 punct ),1
R572 T1012 T1010 compound DSB,repair
R573 T1013 T1010 cc and,repair
R574 T1014 T1015 punct (,2
R575 T1015 T1016 meta 2,synapsis
R576 T1016 T1010 conj synapsis,repair
R577 T1017 T1015 punct ),2
R578 T1018 T1016 compound chromosome,synapsis
R579 T1019 T1020 punct [,12
R580 T1020 T991 parataxis 12,known
R581 T1021 T1020 nummod 2,12
R582 T1022 T1020 punct ",",12
R583 T1023 T1020 punct ],12
R584 T1024 T991 punct .,known
R585 T1026 T1027 prep In,eliminated
R586 T1028 T1026 pobj mice,In
R587 T1029 T1027 punct ", ",eliminated
R588 T1030 T1031 preconj both,spermatocytes
R589 T1031 T1027 nsubjpass spermatocytes,eliminated
R590 T1032 T1031 cc and,spermatocytes
R591 T1033 T1031 conj oocytes,spermatocytes
R592 T1034 T1031 acl harboring,spermatocytes
R593 T1035 T1034 dobj mutations,harboring
R594 T1036 T1037 dep that,disrupt
R595 T1037 T1035 relcl disrupt,mutations
R596 T1038 T1039 compound DSB,repair
R597 T1039 T1037 dobj repair,disrupt
R598 T1040 T1035 punct (,mutations
R599 T1041 T1042 amod such,as
R600 T1042 T1035 prep as,mutations
R601 T1043 T1042 pobj Dmc1,as
R602 T1044 T1043 punct ", ",Dmc1
R603 T1045 T1043 conj Msh5,Dmc1
R604 T1046 T1045 punct ", ",Msh5
R605 T1047 T1045 cc and,Msh5
R606 T1048 T1045 conj Atm,Msh5
R607 T1049 T1027 punct ),eliminated
R608 T1050 T1027 auxpass are,eliminated
R609 T1051 T1027 advmod efficiently,eliminated
R610 T1052 T1027 prep in,eliminated
R611 T1053 T1052 pobj pachynema,in
R612 T1054 T1027 punct ", ",eliminated
R613 T1055 T1027 cc but,eliminated
R614 T1056 T1057 nsubj spermatocytes,are
R615 T1057 T1027 conj are,eliminated
R616 T1058 T1059 advmod much,more
R617 T1059 T1060 advmod more,sensitive
R618 T1060 T1057 acomp sensitive,are
R619 T1061 T1060 prep to,sensitive
R620 T1062 T1063 nmod DSB,defects
R621 T1063 T1061 pobj defects,to
R622 T1064 T1065 npadvmod repair,independent
R623 T1065 T1067 amod independent,synapsis
R624 T1066 T1065 punct –,independent
R625 T1067 T1063 compound synapsis,defects
R626 T1068 T1060 prep than,sensitive
R627 T1069 T1068 pobj oocytes,than
R628 T1070 T1071 punct [,13
R629 T1071 T1027 parataxis 13,eliminated
R630 T1072 T1073 punct –,15
R631 T1073 T1071 prep 15,13
R632 T1074 T1071 punct ],13
R633 T1075 T1027 punct .,eliminated
R634 T1077 T1078 advmod However,remained
R635 T1079 T1078 punct ", ",remained
R636 T1080 T1081 mark because,required
R637 T1081 T1078 advcl required,remained
R638 T1082 T1081 nsubjpass recombination,required
R639 T1083 T1081 auxpass is,required
R640 T1084 T1081 prep for,required
R641 T1085 T1084 pobj synapsis,for
R642 T1086 T1085 prep in,synapsis
R643 T1087 T1086 pobj mice,in
R644 T1088 T1089 punct (,cause
R645 T1089 T1081 parataxis cause,required
R646 T1090 T1089 nsubj mutations,cause
R647 T1091 T1090 prep in,mutations
R648 T1092 T1093 compound recombination,genes
R649 T1093 T1091 pobj genes,in
R650 T1094 T1095 amod such,as
R651 T1095 T1093 prep as,genes
R652 T1096 T1095 pobj Dmc1,as
R653 T1097 T1098 amod extensive,asynapsis
R654 T1098 T1089 dobj asynapsis,cause
R655 T1099 T1100 punct [,16
R656 T1100 T1089 parataxis 16,cause
R657 T1101 T1100 punct ],16
R658 T1102 T1089 punct ),cause
R659 T1103 T1078 punct ", ",remained
R660 T1104 T1078 nsubj it,remained
R661 T1105 T1078 aux has,remained
R662 T1106 T1107 advmod formally,uncertain
R663 T1107 T1078 acomp uncertain,remained
R664 T1108 T1109 mark whether,is
R665 T1109 T1078 advcl is,remained
R666 T1110 T1109 expl there,is
R667 T1111 T1112 det a,checkpoint
R668 T1112 T1109 attr checkpoint,is
R669 T1113 T1112 amod distinct,checkpoint
R670 T1114 T1112 compound pachytene,checkpoint
R671 T1115 T1116 dep that,responds
R672 T1116 T1112 relcl responds,checkpoint
R673 T1117 T1116 prep to,responds
R674 T1118 T1117 pobj defects,to
R675 T1119 T1118 prep in,defects
R676 T1120 T1121 amod meiotic,recombination
R677 T1121 T1119 pobj recombination,in
R678 T1122 T1109 punct ", ",is
R679 T1123 T1109 cc and,is
R713 T1159 T1153 ccomp abolish,identified
R714 T1160 T1159 dobj it,abolish
R715 T1161 T1142 punct .,remain

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T448 4-24 GO:0051598 denotes pachytene checkpoint
T449 37-44 GO:0065007 denotes monitor
T450 60-67 GO:0007126 denotes meiotic
T451 79-89 GO:0008152 denotes metabolism
T452 93-106 NCBITaxon:4932 denotes S. cerevisiae
T453 111-121 NCBITaxon:6239 denotes C. elegans
T454 127-137 GO:0006302 denotes DSB repair
T455 146-165 GO:0007129 denotes chromosome synapsis
T456 177-181 NCBITaxon:10088 denotes mice
T457 188-201 CL:0000017 denotes spermatocytes
T458 206-213 CL:0000023 denotes oocytes
T459 247-257 GO:0006302 denotes DSB repair
T460 267-271 PR:000006536 denotes Dmc1
T461 273-277 PR:000010669 denotes Msh5
T462 283-286 PR:000004427 denotes Atm
T463 318-327 GO:0000239 denotes pachynema
T464 333-346 CL:0000017 denotes spermatocytes
T465 374-384 GO:0006302 denotes DSB repair
T466 397-405 GO:0007129 denotes synapsis
T467 419-426 CL:0000023 denotes oocytes
T468 483-491 GO:0007129 denotes synapsis
T469 495-499 NCBITaxon:10088 denotes mice
T470 528-533 SO:0000704 denotes genes
T471 542-546 PR:000006536 denotes Dmc1
T472 564-572 GO:0007129 denotes synapsis
T473 643-663 GO:0051598 denotes pachytene checkpoint
T474 692-699 GO:0007126 denotes meiotic
T475 772-785 CL:0002371 denotes somatic cells
T476 814-834 GO:0051598 denotes pachytene checkpoint
T477 835-842 GO:0065007 denotes control
T478 861-868 NCBITaxon:40674 denotes mammals

2_test

Id Subject Object Predicate Lexical cue
17696610-16339446-85497886 167-168 16339446 denotes 2
17696610-17174924-85497887 169-171 17174924 denotes 12
17696610-15640358-85497888 428-430 15640358 denotes 13
17696610-12004129-85497888 428-430 12004129 denotes 13
17696610-12077403-85497888 428-430 12077403 denotes 13
17696610-9660953-85497889 574-576 9660953 denotes 16
T92324 167-168 16339446 denotes 2
T88899 169-171 17174924 denotes 12
T6852 428-430 15640358 denotes 13
T86139 428-430 12004129 denotes 13
T6109 428-430 12077403 denotes 13
T38110 574-576 9660953 denotes 16

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T583 4-24 GO:0051598 denotes pachytene checkpoint
T584 37-44 GO:0065007 denotes monitor
T585 60-67 GO:0007126 denotes meiotic
T586 68-78 GO_SO_EXT:chromosome denotes chromosome
T587 79-89 GO:0008152 denotes metabolism
T588 93-106 NCBITaxon:4932 denotes S. cerevisiae
T589 111-121 NCBITaxon:6239 denotes C. elegans
T590 127-137 GO:0006302 denotes DSB repair
T591 146-156 GO_SO_EXT:chromosome denotes chromosome
T592 146-165 GO:0007129 denotes chromosome synapsis
T593 177-181 NCBITaxon:10088 denotes mice
T594 188-201 CL:0000017 denotes spermatocytes
T595 206-213 CL:0000023 denotes oocytes
T596 224-233 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T597 247-257 GO:0006302 denotes DSB repair
T598 267-271 PR_EXT:000006536 denotes Dmc1
T599 273-277 PR_EXT:000010669 denotes Msh5
T600 283-286 PR_EXT:000004427 denotes Atm
T601 304-314 GO_EXT:killing denotes eliminated
T602 318-327 GO:0000239 denotes pachynema
T603 333-346 CL:0000017 denotes spermatocytes
T604 374-384 GO:0006302 denotes DSB repair
T605 397-405 GO:0007129 denotes synapsis
T606 419-426 CL:0000023 denotes oocytes
T607 453-466 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T608 483-491 GO:0007129 denotes synapsis
T609 495-499 NCBITaxon:10088 denotes mice
T610 501-510 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T611 514-527 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T612 528-533 SO_EXT:0000704 denotes genes
T613 542-546 PR_EXT:000006536 denotes Dmc1
T614 564-572 GO:0007129 denotes synapsis
T615 643-663 GO:0051598 denotes pachytene checkpoint
T616 669-677 GO_EXT:reaction_or_response denotes responds
T617 692-699 GO:0007126 denotes meiotic
T618 700-713 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T619 772-785 CL:0002371 denotes somatic cells
T620 780-785 CL_GO_EXT:cell denotes cells
T621 814-834 GO:0051598 denotes pachytene checkpoint
T622 835-842 GO:0065007 denotes control
T623 861-868 NCBITaxon:40674 denotes mammals
T624 879-888 SO_EXT:sequence_alteration_entity_or_process denotes mutations