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PMC:1920263 / 79-1423 JSONTXT

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test2

Id Subject Object Predicate Lexical cue Negation
T27 0-8 Protein denotes APOBEC3G true
T28 10-13 Protein denotes A3G
T29 92-101 Gene_expression denotes expressed
T30 340-343 Protein denotes A3G
T31 438-448 Protein denotes Luciferase
T32 641-644 Protein denotes A3G
T33 645-653 Entity denotes promoter
T34 662-671 Positive_regulation denotes inducible
T35 722-732 Gene_expression denotes expression
T36 805-815 Protein denotes luciferase
T37 981-984 Entity denotes GC-
T38 1233-1239 Entity denotes GC-box
T39 1254-1261 Binding denotes binding
T40 1308-1334 Protein denotes specificity protein (Sp) 1
T41 1339-1342 Protein denotes Sp3
R20 T27 T29 themeOf APOBEC3G,expressed
R21 T28 T27 equivalentTo A3G,APOBEC3G
R22 T33 T34 themeOf promoter,inducible
R23 T33 T32 partOf promoter,A3G
R24 T38 T39 themeOf GC-box,binding
R25 T40 T39 themeOf specificity protein (Sp) 1,binding
R26 T41 T39 themeOf Sp3,binding

GO-CC

Id Subject Object Predicate Lexical cue
T555 630-635 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T556 948-952 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T557 1163-1172 http://purl.obolibrary.org/obo/GO_0000785 denotes chromatin

GO-MF

Id Subject Object Predicate Lexical cue
T554 1254-1261 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

GO-BP

Id Subject Object Predicate Lexical cue
T74 1286-1299 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T75 250-260 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation

UBERON-AE

Id Subject Object Predicate Lexical cue
T42 116-121 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T329 0-8 NNP denotes APOBEC3G
T330 9-10 -LRB- denotes (
T331 10-13 NNP denotes A3G
T332 13-14 -RRB- denotes )
T333 14-15 , denotes ,
T334 16-17 DT denotes a
T335 18-24 NN denotes member
T336 25-27 IN denotes of
T337 28-31 DT denotes the
T338 32-40 RB denotes recently
T339 41-51 VBN denotes discovered
T340 52-58 NN denotes family
T341 59-61 IN denotes of
T342 62-67 JJ denotes human
T343 68-76 NN denotes cytidine
T344 77-87 NNS denotes deaminases
T345 87-88 , denotes ,
T346 89-91 VBZ denotes is
T347 92-101 VBN denotes expressed
T348 102-104 IN denotes in
T349 105-115 JJ denotes peripheral
T350 116-121 NN denotes blood
T351 122-133 NNS denotes lymphocytes
T352 134-137 CC denotes and
T353 138-141 VBZ denotes has
T354 142-146 VBN denotes been
T355 147-152 VBN denotes shown
T356 153-155 TO denotes to
T357 156-158 VB denotes be
T358 159-165 JJ denotes active
T359 166-173 IN denotes against
T360 174-179 NNP denotes HIV-1
T361 180-183 CC denotes and
T362 184-189 JJ denotes other
T363 190-202 NNS denotes retroviruses
T364 202-203 . denotes .
T365 204-206 TO denotes To
T366 207-211 VB denotes gain
T367 212-215 JJ denotes new
T368 216-224 NNS denotes insights
T369 225-229 IN denotes into
T370 230-233 DT denotes the
T371 234-249 JJ denotes transcriptional
T372 250-260 NN denotes regulation
T373 261-263 IN denotes of
T374 264-268 DT denotes this
T375 269-280 NN denotes restriction
T376 281-287 NN denotes factor
T377 287-288 , denotes ,
T378 289-291 PRP denotes we
T379 292-298 VBD denotes cloned
T380 299-302 CC denotes and
T381 303-316 VBD denotes characterized
T382 317-320 DT denotes the
T383 321-329 NN denotes promoter
T384 330-336 NN denotes region
T385 337-339 IN denotes of
T386 340-343 NNP denotes A3G
T387 343-344 . denotes .
T388 345-360 JJ denotes Transcriptional
T389 361-366 NN denotes start
T390 367-372 NNS denotes sites
T391 373-377 VBD denotes were
T392 378-388 VBN denotes identified
T393 389-391 IN denotes by
T394 392-393 CD denotes 5
T395 393-394 SYM denotes ′
T396 394-395 : denotes -
T397 395-400 JJ denotes rapid
T398 401-414 NN denotes amplification
T399 415-417 IN denotes of
T400 418-422 NNP denotes cDNA
T401 423-427 VBZ denotes ends
T402 428-436 NN denotes analysis
T403 436-437 . denotes .
T404 438-448 NNP denotes Luciferase
T405 449-457 NN denotes reporter
T406 458-464 NNS denotes assays
T407 465-477 VBD denotes demonstrated
T408 478-482 IN denotes that
T409 483-484 DT denotes a
T410 485-489 CD denotes 1025
T411 490-492 NN denotes bp
T412 493-496 CD denotes A3G
T413 497-505 NN denotes promoter
T414 506-514 NN denotes sequence
T415 515-516 -LRB- denotes (
T416 516-520 IN denotes from
T417 521-522 CD denotes −
T418 522-525 CD denotes 959
T419 526-528 TO denotes to
T420 529-532 CD denotes +66
T421 533-541 JJ denotes relative
T422 542-544 TO denotes to
T423 545-548 DT denotes the
T424 549-554 JJ denotes major
T425 555-570 JJ denotes transcriptional
T426 571-576 NN denotes start
T427 577-581 NN denotes site
T428 581-582 -RRB- denotes )
T429 583-592 VBD denotes displayed
T430 593-605 JJ denotes constitutive
T431 606-614 NN denotes promoter
T432 615-623 NN denotes activity
T433 623-624 . denotes .
T434 625-627 IN denotes In
T435 628-629 NNP denotes T
T436 630-635 NNS denotes cells
T437 635-636 , denotes ,
T438 637-640 DT denotes the
T439 641-644 NNP denotes A3G
T440 645-653 NN denotes promoter
T441 654-657 VBD denotes was
T442 658-661 RB denotes not
T443 662-671 JJ denotes inducible
T444 672-674 IN denotes by
T445 675-684 JJ denotes mitogenic
T446 685-696 NN denotes stimulation
T447 696-697 , denotes ,
T448 698-708 NN denotes interferon
T449 709-718 NN denotes treatment
T450 719-721 CC denotes or
T451 722-732 NN denotes expression
T452 733-735 IN denotes of
T453 736-741 JJ denotes HIV-1
T454 742-750 NNS denotes proteins
T455 750-751 . denotes .
T456 752-757 VBG denotes Using
T457 758-759 DT denotes a
T458 760-766 NN denotes series
T459 767-769 IN denotes of
T460 770-771 CD denotes 5
T461 771-772 CD denotes ′
T462 773-781 NN denotes deletion
T463 782-790 NN denotes promoter
T464 791-801 NNS denotes constructs
T465 802-804 IN denotes in
T466 805-815 NN denotes luciferase
T467 816-824 NN denotes reporter
T468 825-831 NNS denotes assays
T469 831-832 , denotes ,
T470 833-835 PRP denotes we
T471 836-846 VBD denotes identified
T472 847-848 DT denotes a
T473 849-852 CD denotes 180
T474 853-855 NN denotes bp
T475 856-862 NN denotes region
T476 863-867 WDT denotes that
T477 868-871 VBD denotes was
T478 872-882 JJ denotes sufficient
T479 883-886 IN denotes for
T480 887-891 JJ denotes full
T481 892-900 NN denotes promoter
T482 901-909 NN denotes activity
T483 909-910 . denotes .
T484 911-926 JJ denotes Transcriptional
T485 927-935 NN denotes activity
T486 936-938 IN denotes of
T487 939-943 DT denotes this
T488 944-947 CD denotes A3G
T489 948-952 NN denotes core
T490 953-961 NN denotes promoter
T491 962-965 VBD denotes was
T492 966-975 JJ denotes dependent
T493 976-978 IN denotes on
T494 979-980 DT denotes a
T495 981-987 NNP denotes GC-box
T496 988-989 -LRB- denotes (
T497 989-996 VBN denotes located
T498 997-999 IN denotes at
T499 1000-1008 NN denotes position
T500 1009-1010 CD denotes −
T501 1010-1012 CD denotes 87
T502 1012-1013 NN denotes /
T503 1013-1014 CD denotes −
T504 1014-1016 CD denotes 78
T505 1017-1025 JJ denotes relative
T506 1026-1028 TO denotes to
T507 1029-1032 DT denotes the
T508 1033-1038 JJ denotes major
T509 1039-1054 JJ denotes transcriptional
T510 1055-1060 NN denotes start
T511 1061-1065 NN denotes site
T512 1065-1066 -RRB- denotes )
T513 1067-1070 CC denotes and
T514 1071-1074 VBD denotes was
T515 1075-1084 VBN denotes abolished
T516 1085-1090 IN denotes after
T517 1091-1099 NN denotes mutation
T518 1100-1102 IN denotes of
T519 1103-1107 DT denotes this
T520 1108-1111 NN denotes DNA
T521 1112-1119 NN denotes element
T522 1119-1120 . denotes .
T523 1121-1136 JJ denotes Electrophoretic
T524 1137-1145 NN denotes mobility
T525 1146-1151 NN denotes shift
T526 1152-1158 NNS denotes assays
T527 1159-1162 CC denotes and
T528 1163-1172 NN denotes chromatin
T529 1173-1192 NN denotes immunoprecipitation
T530 1193-1199 NNS denotes assays
T531 1200-1212 VBD denotes demonstrated
T532 1213-1217 IN denotes that
T533 1218-1221 DT denotes the
T534 1222-1232 VBN denotes identified
T535 1233-1239 NNP denotes GC-box
T536 1240-1251 VBD denotes represented
T537 1252-1253 DT denotes a
T538 1254-1261 JJ denotes binding
T539 1262-1266 NN denotes site
T540 1267-1270 IN denotes for
T541 1271-1274 DT denotes the
T542 1275-1285 JJ denotes ubiquitous
T543 1286-1299 NN denotes transcription
T544 1300-1307 NNS denotes factors
T545 1308-1319 NN denotes specificity
T546 1320-1327 NN denotes protein
T547 1328-1329 -LRB- denotes (
T548 1329-1331 NNP denotes Sp
T549 1331-1332 -RRB- denotes )
T550 1333-1334 CD denotes 1
T551 1335-1338 CC denotes and
T552 1339-1342 NNP denotes Sp3
T553 1342-1343 . denotes .
T11945 1300-1307 NNS denotes factors
R278 T330 T331 punct (,A3G
R279 T331 T329 appos A3G,APOBEC3G
R280 T332 T329 punct ),APOBEC3G
R282 T334 T335 det a,member
R284 T336 T335 prep of,member
R285 T337 T340 det the,family
R286 T338 T339 advmod recently,discovered
R287 T339 T340 amod discovered,family
R288 T340 T336 pobj family,of
R289 T341 T340 prep of,family
R290 T342 T344 amod human,deaminases
R291 T343 T344 compound cytidine,deaminases
R292 T344 T341 pobj deaminases,of
R293 T345 T347 punct ",",expressed
R294 T346 T347 auxpass is,expressed
R295 T347 T347 ROOT expressed,expressed
R296 T348 T347 prep in,expressed
R297 T349 T351 amod peripheral,lymphocytes
R298 T350 T351 compound blood,lymphocytes
R299 T351 T348 pobj lymphocytes,in
R300 T352 T347 cc and,expressed
R301 T353 T355 aux has,shown
R302 T354 T355 auxpass been,shown
R303 T355 T347 conj shown,expressed
R304 T356 T357 aux to,be
R305 T357 T355 xcomp be,shown
R306 T358 T357 acomp active,be
R307 T359 T358 prep against,active
R308 T360 T359 pobj HIV-1,against
R309 T361 T360 cc and,HIV-1
R310 T362 T363 amod other,retroviruses
R311 T363 T360 conj retroviruses,HIV-1
R312 T364 T347 punct .,expressed
R313 T365 T366 aux To,gain
R314 T366 T379 advcl gain,cloned
R315 T367 T368 amod new,insights
R316 T368 T366 dobj insights,gain
R317 T369 T368 prep into,insights
R318 T370 T372 det the,regulation
R319 T371 T372 amod transcriptional,regulation
R320 T372 T369 pobj regulation,into
R321 T373 T372 prep of,regulation
R322 T374 T376 det this,factor
R323 T375 T376 compound restriction,factor
R324 T376 T373 pobj factor,of
R325 T377 T379 punct ",",cloned
R326 T378 T379 nsubj we,cloned
R327 T379 T379 ROOT cloned,cloned
R328 T380 T379 cc and,cloned
R329 T381 T379 conj characterized,cloned
R330 T382 T384 det the,region
R331 T383 T384 compound promoter,region
R332 T384 T381 dobj region,characterized
R333 T385 T384 prep of,region
R334 T386 T385 pobj A3G,of
R335 T387 T379 punct .,cloned
R336 T388 T390 amod Transcriptional,sites
R337 T389 T390 compound start,sites
R338 T390 T392 nsubjpass sites,identified
R339 T391 T392 auxpass were,identified
R340 T392 T392 ROOT identified,identified
R341 T393 T392 prep by,identified
R342 T394 T398 nummod 5,amplification
R343 T395 T397 punct ′,rapid
R344 T396 T397 punct -,rapid
R345 T397 T398 amod rapid,amplification
R346 T398 T393 pobj amplification,by
R347 T399 T398 prep of,amplification
R348 T400 T399 pobj cDNA,of
R349 T401 T392 conj ends,identified
R350 T402 T401 dobj analysis,ends
R351 T403 T392 punct .,identified
R352 T404 T406 compound Luciferase,assays
R353 T405 T406 compound reporter,assays
R354 T406 T407 nsubj assays,demonstrated
R355 T407 T407 ROOT demonstrated,demonstrated
R356 T408 T429 mark that,displayed
R357 T409 T414 det a,sequence
R358 T410 T414 nummod 1025,sequence
R359 T411 T414 nmod bp,sequence
R360 T412 T414 nummod A3G,sequence
R361 T413 T414 compound promoter,sequence
R362 T414 T429 nsubj sequence,displayed
R363 T415 T414 punct (,sequence
R364 T416 T414 prep from,sequence
R365 T417 T420 quantmod −,+66
R366 T418 T420 quantmod 959,+66
R367 T419 T420 quantmod to,+66
R368 T420 T416 pobj +66,from
R369 T421 T414 amod relative,sequence
R370 T422 T421 prep to,relative
R371 T423 T427 det the,site
R372 T424 T427 amod major,site
R373 T425 T427 amod transcriptional,site
R374 T426 T427 compound start,site
R375 T427 T422 pobj site,to
R376 T428 T414 punct ),sequence
R377 T429 T407 ccomp displayed,demonstrated
R378 T430 T432 amod constitutive,activity
R379 T431 T432 compound promoter,activity
R380 T432 T429 dobj activity,displayed
R381 T433 T407 punct .,demonstrated
R382 T434 T441 prep In,was
R383 T435 T436 compound T,cells
R384 T436 T434 pobj cells,In
R385 T437 T441 punct ",",was
R386 T438 T440 det the,promoter
R387 T439 T440 compound A3G,promoter
R388 T440 T441 nsubj promoter,was
R389 T441 T441 ROOT was,was
R390 T442 T441 neg not,was
R391 T443 T441 attr inducible,was
R392 T444 T443 prep by,inducible
R393 T445 T446 amod mitogenic,stimulation
R394 T446 T444 pobj stimulation,by
R395 T447 T446 punct ",",stimulation
R396 T448 T449 compound interferon,treatment
R397 T449 T446 conj treatment,stimulation
R398 T450 T449 cc or,treatment
R399 T451 T449 conj expression,treatment
R400 T452 T451 prep of,expression
R403 T455 T441 punct .,was
R404 T456 T471 advcl Using,identified
R405 T457 T458 det a,series
R406 T458 T456 dobj series,Using
R407 T459 T458 prep of,series
R408 T460 T464 nummod 5,constructs
R409 T461 T464 nummod ′,constructs
R410 T462 T464 compound deletion,constructs
R411 T463 T464 compound promoter,constructs
R412 T464 T459 pobj constructs,of
R413 T465 T464 prep in,constructs
R414 T466 T468 compound luciferase,assays
R415 T467 T468 compound reporter,assays
R416 T468 T465 pobj assays,in
R417 T469 T471 punct ",",identified
R418 T470 T471 nsubj we,identified
R419 T471 T471 ROOT identified,identified
R420 T472 T475 det a,region
R421 T473 T475 nummod 180,region
R422 T474 T475 compound bp,region
R423 T475 T471 dobj region,identified
R424 T476 T477 nsubj that,was
R425 T477 T475 relcl was,region
R426 T478 T477 acomp sufficient,was
R427 T479 T478 prep for,sufficient
R428 T480 T482 amod full,activity
R429 T481 T482 compound promoter,activity
R430 T482 T479 pobj activity,for
R431 T483 T471 punct .,identified
R432 T484 T485 amod Transcriptional,activity
R433 T485 T491 nsubj activity,was
R434 T486 T485 prep of,activity
R435 T487 T490 det this,promoter
R436 T488 T490 nummod A3G,promoter
R437 T489 T490 compound core,promoter
R438 T490 T486 pobj promoter,of
R439 T491 T491 ROOT was,was
R440 T492 T491 acomp dependent,was
R441 T493 T492 prep on,dependent
R442 T494 T495 det a,GC-box
R443 T495 T493 pobj GC-box,on
R444 T496 T495 punct (,GC-box
R445 T497 T495 acl located,GC-box
R446 T498 T497 prep at,located
R447 T499 T498 pobj position,at
R448 T500 T499 nummod −,position
R449 T501 T504 quantmod 87,78
R450 T502 T504 quantmod /,78
R451 T503 T502 nummod −,/
R452 T504 T495 appos 78,GC-box
R453 T505 T504 quantmod relative,78
R454 T506 T505 prep to,relative
R455 T507 T511 det the,site
R456 T508 T511 amod major,site
R457 T509 T511 amod transcriptional,site
R458 T510 T511 compound start,site
R459 T511 T506 pobj site,to
R460 T512 T504 punct ),78
R461 T513 T491 cc and,was
R462 T514 T515 auxpass was,abolished
R463 T515 T491 conj abolished,was
R464 T516 T515 prep after,abolished
R465 T517 T516 pobj mutation,after
R466 T518 T517 prep of,mutation
R467 T519 T521 det this,element
R468 T520 T521 compound DNA,element
R469 T521 T518 pobj element,of
R470 T522 T491 punct .,was
R471 T523 T526 amod Electrophoretic,assays
R472 T524 T525 compound mobility,shift
R473 T525 T526 compound shift,assays
R474 T526 T531 nsubj assays,demonstrated
R475 T527 T526 cc and,assays
R476 T528 T530 nmod chromatin,assays
R477 T529 T530 compound immunoprecipitation,assays
R478 T530 T526 conj assays,assays
R479 T531 T531 ROOT demonstrated,demonstrated
R480 T532 T536 mark that,represented
R483 T535 T536 nsubj GC-box,represented
R484 T536 T531 ccomp represented,demonstrated
R485 T537 T539 det a,site
R486 T538 T539 amod binding,site
R487 T539 T536 dobj site,represented
R488 T540 T539 prep for,site
R489 T541 T546 det the,protein
R490 T542 T544 amod ubiquitous,factors
R491 T543 T544 compound transcription,factors
R492 T544 T546 compound factors,protein
R493 T545 T546 compound specificity,protein
R494 T546 T540 pobj protein,for
R495 T547 T548 punct (,Sp
R496 T548 T546 appos Sp,protein
R497 T549 T531 punct ),demonstrated
R498 T550 T549 nummod 1,)
R499 T551 T550 cc and,1
R500 T552 T550 conj Sp3,1
R501 T553 T531 punct .,demonstrated
R401 T453 T454 amod HIV-1,proteins
R402 T454 T452 pobj proteins,of
R481 T533 T535 det the,GC-box
R482 T534 T535 amod identified,GC-box

sentences

Id Subject Object Predicate Lexical cue
T65 0-203 Sentence denotes APOBEC3G (A3G), a member of the recently discovered family of human cytidine deaminases, is expressed in peripheral blood lymphocytes and has been shown to be active against HIV-1 and other retroviruses.
T66 204-344 Sentence denotes To gain new insights into the transcriptional regulation of this restriction factor, we cloned and characterized the promoter region of A3G.
T67 345-437 Sentence denotes Transcriptional start sites were identified by 5′-rapid amplification of cDNA ends analysis.
T68 438-624 Sentence denotes Luciferase reporter assays demonstrated that a 1025 bp A3G promoter sequence (from −959 to +66 relative to the major transcriptional start site) displayed constitutive promoter activity.
T69 625-751 Sentence denotes In T cells, the A3G promoter was not inducible by mitogenic stimulation, interferon treatment or expression of HIV-1 proteins.
T70 752-910 Sentence denotes Using a series of 5′ deletion promoter constructs in luciferase reporter assays, we identified a 180 bp region that was sufficient for full promoter activity.
T71 911-1120 Sentence denotes Transcriptional activity of this A3G core promoter was dependent on a GC-box (located at position −87/−78 relative to the major transcriptional start site) and was abolished after mutation of this DNA element.
T72 1121-1343 Sentence denotes Electrophoretic mobility shift assays and chromatin immunoprecipitation assays demonstrated that the identified GC-box represented a binding site for the ubiquitous transcription factors specificity protein (Sp) 1 and Sp3.
T3 0-203 Sentence denotes APOBEC3G (A3G), a member of the recently discovered family of human cytidine deaminases, is expressed in peripheral blood lymphocytes and has been shown to be active against HIV-1 and other retroviruses.
T4 204-344 Sentence denotes To gain new insights into the transcriptional regulation of this restriction factor, we cloned and characterized the promoter region of A3G.
T5 345-437 Sentence denotes Transcriptional start sites were identified by 5′-rapid amplification of cDNA ends analysis.
T6 438-624 Sentence denotes Luciferase reporter assays demonstrated that a 1025 bp A3G promoter sequence (from −959 to +66 relative to the major transcriptional start site) displayed constitutive promoter activity.
T7 625-751 Sentence denotes In T cells, the A3G promoter was not inducible by mitogenic stimulation, interferon treatment or expression of HIV-1 proteins.
T8 752-910 Sentence denotes Using a series of 5′ deletion promoter constructs in luciferase reporter assays, we identified a 180 bp region that was sufficient for full promoter activity.
T9 911-1120 Sentence denotes Transcriptional activity of this A3G core promoter was dependent on a GC-box (located at position −87/−78 relative to the major transcriptional start site) and was abolished after mutation of this DNA element.
T10 1121-1343 Sentence denotes Electrophoretic mobility shift assays and chromatin immunoprecipitation assays demonstrated that the identified GC-box represented a binding site for the ubiquitous transcription factors specificity protein (Sp) 1 and Sp3.

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T87 0-8 NN denotes APOBEC3G
T88 9-10 -LRB- denotes (
T89 10-13 NN denotes A3G
T90 13-14 -RRB- denotes )
T91 14-15 -COMMA- denotes ,
T92 16-17 DT denotes a
T93 18-24 NN denotes member
T94 25-27 IN denotes of
T95 28-31 DT denotes the
T96 32-40 RB denotes recently
T97 41-51 VB denotes discovered
T98 52-58 NN denotes family
T99 59-61 IN denotes of
T100 62-67 JJ denotes human
T101 68-76 NN denotes cytidine
T102 77-87 NN denotes deaminases
T103 87-88 -COMMA- denotes ,
T104 89-91 VB denotes is
T105 92-101 VB denotes expressed
T106 102-104 IN denotes in
T107 105-115 JJ denotes peripheral
T108 116-121 NN denotes blood
T109 122-133 NN denotes lymphocytes
T110 134-137 CC denotes and
T111 138-141 VB denotes has
T112 142-146 VB denotes been
T113 147-152 VB denotes shown
T114 153-155 TO denotes to
T115 156-158 VB denotes be
T116 159-165 JJ denotes active
T117 166-173 IN denotes against
T118 174-179 NN denotes HIV-1
T119 180-183 CC denotes and
T120 184-189 JJ denotes other
T121 190-202 NN denotes retroviruses
T122 204-206 TO denotes To
T123 207-211 VB denotes gain
T124 212-215 JJ denotes new
T125 216-224 NN denotes insights
T126 225-229 IN denotes into
T127 230-233 DT denotes the
T128 234-249 JJ denotes transcriptional
T129 250-260 NN denotes regulation
T130 261-263 IN denotes of
T131 264-268 DT denotes this
T132 269-280 NN denotes restriction
T133 281-287 NN denotes factor
T134 287-288 -COMMA- denotes ,
T135 289-291 PRP denotes we
T136 292-298 VB denotes cloned
T137 299-302 CC denotes and
T138 303-316 VB denotes characterized
T139 317-320 DT denotes the
T140 321-329 NN denotes promoter
T141 330-336 NN denotes region
T142 337-339 IN denotes of
T143 340-343 NN denotes A3G
T144 345-360 JJ denotes Transcriptional
T145 361-366 NN denotes start
T146 367-372 NN denotes sites
T147 373-377 VB denotes were
T148 378-388 VB denotes identified
T149 389-391 IN denotes by
T150 392-400 JJ denotes 5′-rapid
T151 401-414 NN denotes amplification
T152 415-417 IN denotes of
T153 418-422 NN denotes cDNA
T154 423-427 VB denotes ends
T155 428-436 NN denotes analysis
T156 438-448 NN denotes Luciferase
T157 449-457 NN denotes reporter
T158 458-464 NN denotes assays
T159 465-477 VB denotes demonstrated
T160 478-482 IN denotes that
T161 483-484 DT denotes a
T162 485-492 NN denotes 1025 bp
T163 493-496 NN denotes A3G
T164 497-505 NN denotes promoter
T165 506-514 NN denotes sequence
T166 515-516 -LRB- denotes (
T167 516-520 IN denotes from
T168 521-525 CD denotes −959
T169 526-528 TO denotes to
T170 529-532 CD denotes +66
T171 533-541 JJ denotes relative
T172 542-544 TO denotes to
T173 545-548 DT denotes the
T174 549-554 JJ denotes major
T175 555-570 JJ denotes transcriptional
T176 571-576 NN denotes start
T177 577-581 NN denotes site
T178 581-582 -RRB- denotes )
T179 583-592 VB denotes displayed
T180 593-605 JJ denotes constitutive
T181 606-614 NN denotes promoter
T182 615-623 NN denotes activity
T183 625-627 IN denotes In
T184 628-629 NN denotes T
T185 630-635 NN denotes cells
T186 635-636 -COMMA- denotes ,
T187 637-640 DT denotes the
T188 641-644 NN denotes A3G
T189 645-653 NN denotes promoter
T190 654-657 VB denotes was
T191 658-661 RB denotes not
T192 662-671 JJ denotes inducible
T193 672-674 IN denotes by
T194 675-684 JJ denotes mitogenic
T195 685-696 NN denotes stimulation
T196 696-697 -COMMA- denotes ,
T197 698-708 NN denotes interferon
T198 709-718 NN denotes treatment
T199 719-721 CC denotes or
T200 722-732 NN denotes expression
T201 733-735 IN denotes of
T202 736-741 NN denotes HIV-1
T203 742-750 NN denotes proteins
T204 752-757 VB denotes Using
T205 758-759 DT denotes a
T206 760-766 NN denotes series
T207 767-769 IN denotes of
T208 770-772 NN denotes 5′
T209 773-781 NN denotes deletion
T210 782-790 NN denotes promoter
T211 791-801 NN denotes constructs
T212 802-804 IN denotes in
T213 805-815 NN denotes luciferase
T214 816-824 NN denotes reporter
T215 825-831 NN denotes assays
T216 831-832 -COMMA- denotes ,
T217 833-835 PRP denotes we
T218 836-846 VB denotes identified
T219 847-848 DT denotes a
T220 849-855 NN denotes 180 bp
T221 856-862 NN denotes region
T222 863-867 WDT denotes that
T223 868-871 VB denotes was
T224 872-882 JJ denotes sufficient
T225 883-886 IN denotes for
T226 887-891 JJ denotes full
T227 892-900 NN denotes promoter
T228 901-909 NN denotes activity
T229 911-926 JJ denotes Transcriptional
T230 927-935 NN denotes activity
T231 936-938 IN denotes of
T232 939-943 DT denotes this
T233 944-947 NN denotes A3G
T234 948-952 NN denotes core
T235 953-961 NN denotes promoter
T236 962-965 VB denotes was
T237 966-975 JJ denotes dependent
T238 976-978 IN denotes on
T239 979-980 DT denotes a
T240 981-987 NN denotes GC-box
T241 988-989 -LRB- denotes (
T242 989-996 JJ denotes located
T243 997-999 IN denotes at
T244 1000-1008 NN denotes position
T245 1009-1016 NN denotes −87/−78
T246 1017-1025 JJ denotes relative
T247 1026-1028 TO denotes to
T248 1029-1032 DT denotes the
T249 1033-1038 JJ denotes major
T250 1039-1054 JJ denotes transcriptional
T251 1055-1060 NN denotes start
T252 1061-1065 NN denotes site
T253 1065-1066 -RRB- denotes )
T254 1067-1070 CC denotes and
T255 1071-1074 VB denotes was
T256 1075-1084 VB denotes abolished
T257 1085-1090 IN denotes after
T258 1091-1099 NN denotes mutation
T259 1100-1102 IN denotes of
T260 1103-1107 DT denotes this
T261 1108-1111 NN denotes DNA
T262 1112-1119 NN denotes element
T263 1121-1136 JJ denotes Electrophoretic
T264 1137-1145 NN denotes mobility
T265 1146-1151 NN denotes shift
T266 1152-1158 NN denotes assays
T267 1159-1162 CC denotes and
T268 1163-1172 NN denotes chromatin
T269 1173-1192 NN denotes immunoprecipitation
T270 1193-1199 NN denotes assays
T271 1200-1212 VB denotes demonstrated
T272 1213-1217 IN denotes that
T273 1218-1221 DT denotes the
T274 1222-1232 VB denotes identified
T275 1233-1239 NN denotes GC-box
T276 1240-1251 VB denotes represented
T277 1252-1253 DT denotes a
T278 1254-1261 VB denotes binding
T279 1262-1266 NN denotes site
T280 1267-1270 IN denotes for
T281 1271-1274 DT denotes the
T282 1275-1285 JJ denotes ubiquitous
T283 1286-1299 NN denotes transcription
T284 1300-1307 NN denotes factors
T285 1308-1319 NN denotes specificity
T286 1320-1327 NN denotes protein
T287 1328-1329 -LRB- denotes (
T288 1329-1331 NN denotes Sp
T289 1331-1332 -RRB- denotes )
T290 1333-1334 CD denotes 1
T291 1335-1338 CC denotes and
T292 1339-1342 NN denotes Sp3
T11430 1300-1307 NN denotes factors
R52 T87 T88 arg1Of APOBEC3G,(
R53 T87 T91 arg1Of APOBEC3G,","
R54 T87 T104 arg1Of APOBEC3G,is
R55 T87 T105 arg2Of APOBEC3G,expressed
R56 T87 T111 arg1Of APOBEC3G,has
R57 T87 T112 arg1Of APOBEC3G,been
R58 T87 T113 arg2Of APOBEC3G,shown
R59 T87 T115 arg1Of APOBEC3G,be
R60 T87 T116 arg1Of APOBEC3G,active
R61 T89 T88 arg2Of A3G,(
R62 T90 T88 arg3Of ),(
R63 T93 T91 arg2Of member,","
R64 T93 T92 arg1Of member,a
R65 T93 T94 arg1Of member,of
R66 T97 T96 arg1Of discovered,recently
R67 T98 T94 arg2Of family,of
R68 T98 T95 arg1Of family,the
R69 T98 T97 arg1Of family,discovered
R70 T98 T99 arg1Of family,of
R71 T102 T99 arg2Of deaminases,of
R72 T102 T100 arg1Of deaminases,human
R73 T102 T101 arg1Of deaminases,cytidine
R74 T105 T104 arg2Of expressed,is
R75 T105 T106 arg1Of expressed,in
R76 T105 T110 arg1Of expressed,and
R77 T109 T106 arg2Of lymphocytes,in
R78 T109 T107 arg1Of lymphocytes,peripheral
R79 T109 T108 arg1Of lymphocytes,blood
R80 T110 T103 arg1Of and,","
R81 T113 T110 arg2Of shown,and
R82 T113 T111 arg2Of shown,has
R83 T113 T112 arg2Of shown,been
R84 T115 T113 arg3Of be,shown
R85 T115 T114 arg1Of be,to
R86 T116 T115 arg2Of active,be
R87 T116 T117 arg1Of active,against
R88 T118 T119 arg1Of HIV-1,and
R89 T119 T117 arg2Of and,against
R90 T121 T119 arg2Of retroviruses,and
R91 T121 T120 arg1Of retroviruses,other
R92 T123 T122 arg1Of gain,To
R93 T125 T123 arg2Of insights,gain
R94 T125 T124 arg1Of insights,new
R95 T125 T126 arg1Of insights,into
R96 T129 T126 arg2Of regulation,into
R97 T129 T127 arg1Of regulation,the
R98 T129 T128 arg1Of regulation,transcriptional
R99 T129 T130 arg1Of regulation,of
R100 T133 T130 arg2Of factor,of
R101 T133 T131 arg1Of factor,this
R102 T133 T132 arg1Of factor,restriction
R103 T135 T123 arg1Of we,gain
R104 T135 T136 arg1Of we,cloned
R105 T135 T138 arg1Of we,characterized
R106 T136 T137 arg1Of cloned,and
R107 T137 T122 modOf and,To
R108 T137 T134 arg1Of and,","
R109 T138 T137 arg2Of characterized,and
R110 T141 T136 arg2Of region,cloned
R111 T141 T138 arg2Of region,characterized
R112 T141 T139 arg1Of region,the
R113 T141 T140 arg1Of region,promoter
R114 T141 T142 arg1Of region,of
R115 T143 T142 arg2Of A3G,of
R116 T146 T144 arg1Of sites,Transcriptional
R117 T146 T145 arg1Of sites,start
R118 T146 T147 arg1Of sites,were
R119 T146 T148 arg2Of sites,identified
R120 T148 T147 arg2Of identified,were
R121 T151 T148 arg1Of amplification,identified
R122 T151 T149 arg2Of amplification,by
R123 T151 T150 arg1Of amplification,5′-rapid
R124 T153 T152 arg1Of cDNA,of
R125 T153 T154 arg1Of cDNA,ends
R126 T154 T147 modOf ends,were
R127 T155 T154 arg2Of analysis,ends
R128 T158 T156 arg1Of assays,Luciferase
R129 T158 T157 arg1Of assays,reporter
R130 T158 T159 arg1Of assays,demonstrated
R131 T165 T161 arg1Of sequence,a
R132 T165 T162 arg1Of sequence,1025 bp
R133 T165 T163 arg1Of sequence,A3G
R134 T165 T164 arg1Of sequence,promoter
R135 T165 T166 arg1Of sequence,(
R136 T165 T179 arg1Of sequence,displayed
R137 T167 T166 arg2Of from,(
R138 T170 T167 arg2Of +66,from
R139 T170 T168 arg1Of +66,−959
R140 T170 T169 arg1Of +66,to
R141 T170 T172 arg1Of +66,to
R142 T172 T171 arg1Of to,relative
R143 T177 T172 arg2Of site,to
R144 T177 T173 arg1Of site,the
R145 T177 T174 arg1Of site,major
R146 T177 T175 arg1Of site,transcriptional
R147 T177 T176 arg1Of site,start
R148 T178 T166 arg3Of ),(
R149 T179 T159 arg2Of displayed,demonstrated
R150 T179 T160 arg1Of displayed,that
R151 T182 T179 arg2Of activity,displayed
R152 T182 T180 arg1Of activity,constitutive
R153 T182 T181 arg1Of activity,promoter
R154 T185 T183 arg2Of cells,In
R155 T185 T184 arg1Of cells,T
R156 T189 T187 arg1Of promoter,the
R157 T189 T188 arg1Of promoter,A3G
R158 T189 T190 arg1Of promoter,was
R159 T189 T192 arg1Of promoter,inducible
R160 T190 T183 arg1Of was,In
R161 T190 T186 arg1Of was,","
R162 T190 T191 arg1Of was,not
R163 T192 T190 arg2Of inducible,was
R164 T192 T193 arg1Of inducible,by
R165 T195 T194 arg1Of stimulation,mitogenic
R166 T195 T196 arg1Of stimulation,","
R167 T196 T199 arg1Of ",",or
R168 T198 T196 arg2Of treatment,","
R169 T198 T197 arg1Of treatment,interferon
R170 T199 T193 arg2Of or,by
R171 T199 T201 arg1Of or,of
R172 T200 T199 arg2Of expression,or
R173 T203 T201 arg2Of proteins,of
R174 T203 T202 arg1Of proteins,HIV-1
R175 T206 T204 arg2Of series,Using
R176 T206 T205 arg1Of series,a
R177 T206 T207 arg1Of series,of
R178 T206 T212 arg1Of series,in
R179 T211 T207 arg2Of constructs,of
R180 T211 T208 arg1Of constructs,5′
R181 T211 T209 arg1Of constructs,deletion
R182 T211 T210 arg1Of constructs,promoter
R183 T215 T212 arg2Of assays,in
R184 T215 T213 arg1Of assays,luciferase
R185 T215 T214 arg1Of assays,reporter
R186 T217 T204 arg1Of we,Using
R187 T217 T218 arg1Of we,identified
R188 T218 T204 modOf identified,Using
R189 T218 T216 arg1Of identified,","
R190 T221 T218 arg2Of region,identified
R191 T221 T219 arg1Of region,a
R192 T221 T220 arg1Of region,180 bp
R193 T221 T222 arg1Of region,that
R194 T221 T223 arg1Of region,was
R195 T221 T224 arg1Of region,sufficient
R196 T224 T223 arg2Of sufficient,was
R197 T224 T225 arg1Of sufficient,for
R198 T228 T225 arg2Of activity,for
R199 T228 T226 arg1Of activity,full
R200 T228 T227 arg1Of activity,promoter
R201 T230 T229 arg1Of activity,Transcriptional
R202 T230 T231 arg1Of activity,of
R203 T230 T236 arg1Of activity,was
R204 T230 T237 arg1Of activity,dependent
R205 T230 T255 arg1Of activity,was
R206 T230 T256 arg2Of activity,abolished
R207 T235 T231 arg2Of promoter,of
R208 T235 T232 arg1Of promoter,this
R209 T235 T233 arg1Of promoter,A3G
R210 T235 T234 arg1Of promoter,core
R211 T236 T254 arg1Of was,and
R212 T237 T236 arg2Of dependent,was
R213 T237 T238 arg1Of dependent,on
R214 T240 T238 arg2Of GC-box,on
R215 T240 T239 arg1Of GC-box,a
R216 T240 T241 arg1Of GC-box,(
R217 T242 T241 arg2Of located,(
R218 T242 T243 arg1Of located,at
R219 T242 T247 arg1Of located,to
R220 T245 T243 arg2Of −87/−78,at
R221 T245 T244 arg1Of −87/−78,position
R222 T247 T246 arg1Of to,relative
R223 T252 T247 arg2Of site,to
R224 T252 T248 arg1Of site,the
R225 T252 T249 arg1Of site,major
R226 T252 T250 arg1Of site,transcriptional
R227 T252 T251 arg1Of site,start
R228 T253 T241 arg3Of ),(
R229 T256 T254 arg2Of abolished,and
R230 T256 T255 arg2Of abolished,was
R231 T256 T257 arg1Of abolished,after
R232 T258 T257 arg2Of mutation,after
R233 T258 T259 arg1Of mutation,of
R234 T262 T259 arg2Of element,of
R235 T262 T260 arg1Of element,this
R236 T262 T261 arg1Of element,DNA
R237 T266 T263 arg1Of assays,Electrophoretic
R238 T266 T264 arg1Of assays,mobility
R239 T266 T265 arg1Of assays,shift
R240 T266 T267 arg1Of assays,and
R241 T267 T271 arg1Of and,demonstrated
R242 T270 T267 arg2Of assays,and
R243 T270 T268 arg1Of assays,chromatin
R244 T270 T269 arg1Of assays,immunoprecipitation
R245 T275 T273 arg1Of GC-box,the
R246 T275 T274 arg2Of GC-box,identified
R247 T275 T276 arg1Of GC-box,represented
R248 T276 T271 arg2Of represented,demonstrated
R249 T276 T272 arg1Of represented,that
R250 T279 T276 arg2Of site,represented
R251 T279 T277 arg1Of site,a
R252 T279 T278 arg1Of site,binding
R253 T279 T280 arg1Of site,for
R254 T286 T281 arg1Of protein,the
R255 T286 T282 arg1Of protein,ubiquitous
R256 T286 T283 arg1Of protein,transcription
R257 T286 T284 arg1Of protein,factors
R258 T286 T285 arg1Of protein,specificity
R259 T286 T287 arg1Of protein,(
R260 T286 T290 arg1Of protein,1
R261 T286 T291 arg1Of protein,and
R262 T288 T287 arg2Of Sp,(
R263 T289 T287 arg3Of ),(
R264 T291 T280 arg2Of and,for
R265 T292 T291 arg2Of Sp3,and

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T293 264-287 Anaphor denotes this restriction factor
T294 0-8 Antecedent denotes APOBEC3G
R572 T293 T294 boundBy this restriction factor,APOBEC3G

events-check-again

Id Subject Object Predicate Lexical cue Negation
T663 0-8 Protein denotes APOBEC3G
T664 10-13 Protein denotes A3G
T665 92-101 Gene_expression denotes expressed
T666 250-260 Regulation denotes regulation
T667 340-343 Protein denotes A3G
T668 438-448 Protein denotes Luciferase
T669 641-644 Protein denotes A3G
T670 645-653 Entity denotes promoter
T671 662-671 Positive_regulation denotes inducible true
T672 805-815 Protein denotes luciferase
T673 1233-1239 Entity denotes GC-box
T674 1254-1261 Binding denotes binding
T675 1254-1261 Binding denotes binding
T676 1308-1334 Protein denotes specificity protein (Sp) 1
T677 1339-1342 Protein denotes Sp3
R550 T663 T666 themeOf APOBEC3G,regulation
R551 T663 T665 themeOf APOBEC3G,expressed
R552 T664 T663 equivalentTo A3G,APOBEC3G
R553 T670 T671 themeOf promoter,inducible
R554 T670 T669 partOf promoter,A3G
R555 T673 T674 themeOf GC-box,binding
R556 T673 T669 partOf GC-box,A3G
R557 T673 T675 themeOf GC-box,binding
R558 T676 T674 themeOf specificity protein (Sp) 1,binding
R559 T677 T675 themeOf Sp3,binding

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T684 0-8 Protein denotes APOBEC3G
T685 10-13 Protein denotes A3G
T686 52-87 Protein denotes family of human cytidine deaminases
T687 92-101 Gene_expression denotes expressed
T688 92-101 Gene_expression denotes expressed
T689 340-343 Protein denotes A3G
T690 438-448 Protein denotes Luciferase
T691 641-653 Protein denotes A3G promoter
T692 698-708 Protein denotes interferon
T693 805-815 Protein denotes luciferase
T694 944-961 Protein denotes A3G core promoter
T695 1075-1084 Negative_regulation denotes abolished
T696 1286-1334 Protein denotes transcription factors specificity protein (Sp) 1
T697 1339-1342 Protein denotes Sp3
T698 1233-1239 Entity denotes GC-box
T699 1254-1261 Binding denotes binding
T700 1254-1261 Binding denotes binding
R565 T684 T687 themeOf APOBEC3G,expressed
R566 T685 T688 themeOf A3G,expressed
R567 T694 T695 themeOf A3G core promoter,abolished
R568 T696 T699 themeOf transcription factors specificity protein (Sp) 1,binding
R569 T697 T700 themeOf Sp3,binding
R570 T698 T699 Site GC-box,binding
R571 T698 T700 Site GC-box,binding

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation
T49 0-8 Protein denotes APOBEC3G
T50 10-13 Protein denotes A3G
T51 92-101 Gene_expression denotes expressed
T52 250-260 Regulation denotes regulation
T53 340-343 Protein denotes A3G
T54 438-448 Protein denotes Luciferase
T55 641-644 Protein denotes A3G
T56 645-653 Entity denotes promoter
T57 662-671 Positive_regulation denotes inducible true
T58 805-815 Protein denotes luciferase
T59 1233-1239 Entity denotes GC-box
T60 1254-1261 Binding denotes binding
T61 1254-1261 Binding denotes binding
T62 1308-1334 Protein denotes specificity protein (Sp) 1
T63 1339-1342 Protein denotes Sp3
R32 T49 T52 themeOf APOBEC3G,regulation
R33 T49 T51 themeOf APOBEC3G,expressed
R34 T50 T49 equivalentTo A3G,APOBEC3G
R35 T56 T57 themeOf promoter,inducible
R36 T56 T55 partOf promoter,A3G
R37 T59 T60 themeOf GC-box,binding
R38 T59 T55 partOf GC-box,A3G
R39 T59 T61 themeOf GC-box,binding
R40 T62 T60 themeOf specificity protein (Sp) 1,binding
R41 T63 T61 themeOf Sp3,binding

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T298 0-8 Q9HC16 denotes APOBEC3G
T299 10-13 Q9HC16 denotes A3G
T300 340-343 Q9HC16 denotes A3G
T301 438-448 P08659 denotes Luciferase
T302 493-496 Q9HC16 denotes A3G
T303 533-541 Q04864 denotes relative
T304 641-644 Q9HC16 denotes A3G
T305 805-815 P08659 denotes luciferase
T306 944-947 Q9HC16 denotes A3G
T307 1017-1025 Q04864 denotes relative
T308 1339-1342 Q02447 denotes Sp3