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PMC:1914394 / 7066-7892 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T4340 0-10 VBG denotes Activating
T4341 25-32 VB denotes promote
T4342 11-15 NNS denotes E2fs
T4343 16-19 MD denotes may
T4344 20-24 RB denotes also
T4345 33-42 NN denotes apoptosis
T4346 43-45 IN denotes in
T4347 46-49 DT denotes the
T4348 56-62 NN denotes retina
T4349 50-52 NN denotes Rb
T4350 53-55 NN denotes KO
T4351 63-64 -LRB- denotes (
T4352 71-73 NN denotes 1B
T4353 64-70 NN denotes Figure
T4354 73-74 -RRB- denotes )
T4355 74-75 . denotes .
T4356 75-160 sentence denotes Originally, E2f1 was considered the primary pro-apoptotic member of the family [10].
T4357 76-86 RB denotes Originally
T4358 97-107 VBN denotes considered
T4359 86-88 , denotes ,
T4360 88-92 NN denotes E2f1
T4361 93-96 VBD denotes was
T4362 108-111 DT denotes the
T4363 134-140 NN denotes member
T4364 112-119 JJ denotes primary
T4365 120-133 JJ denotes pro-apoptotic
T4366 141-143 IN denotes of
T4367 144-147 DT denotes the
T4368 148-154 NN denotes family
T4369 155-156 -LRB- denotes [
T4370 156-158 CD denotes 10
T4371 158-159 -RRB- denotes ]
T4372 159-160 . denotes .
T4373 160-337 sentence denotes However, this view was reevaluated when it was shown that either E2f1 or E2f3 deletion rescues apoptosis in the developing central nervous system (CNS) of Rb KO embryos [6,11].
T4374 161-168 RB denotes However
T4375 184-195 VBN denotes reevaluated
T4376 168-170 , denotes ,
T4377 170-174 DT denotes this
T4378 175-179 NN denotes view
T4379 180-183 VBD denotes was
T4380 196-200 WRB denotes when
T4381 208-213 VBN denotes shown
T4382 201-203 PRP denotes it
T4383 204-207 VBD denotes was
T4384 214-218 IN denotes that
T4385 248-255 VBZ denotes rescues
T4386 219-225 CC denotes either
T4387 226-230 NN denotes E2f1
T4388 239-247 NN denotes deletion
T4389 231-233 CC denotes or
T4390 234-238 NN denotes E2f3
T4391 256-265 NN denotes apoptosis
T4392 266-268 IN denotes in
T4393 269-272 DT denotes the
T4394 300-306 NN denotes system
T4395 273-283 VBG denotes developing
T4396 284-291 JJ denotes central
T4397 292-299 JJ denotes nervous
T4398 307-308 -LRB- denotes (
T4399 308-311 NN denotes CNS
T4400 311-312 -RRB- denotes )
T4401 313-315 IN denotes of
T4402 316-318 NN denotes Rb
T4403 319-321 NN denotes KO
T4404 322-329 NNS denotes embryos
T4405 330-331 -LRB- denotes [
T4406 333-335 CD denotes 11
T4407 331-332 CD denotes 6
T4408 332-333 , denotes ,
T4409 335-336 -RRB- denotes ]
T4410 336-337 . denotes .
T4411 337-451 sentence denotes Subsequently, CNS apoptosis was shown to be an indirect result of placental defects and probable hypoxia [12–14].
T4412 338-350 RB denotes Subsequently
T4413 370-375 VBN denotes shown
T4414 350-352 , denotes ,
T4415 352-355 NN denotes CNS
T4416 356-365 NN denotes apoptosis
T4417 366-369 VBD denotes was
T4418 376-378 TO denotes to
T4419 379-381 VB denotes be
T4420 382-384 DT denotes an
T4421 394-400 NN denotes result
T4422 385-393 JJ denotes indirect
T4423 401-403 IN denotes of
T4424 404-413 JJ denotes placental
T4425 414-421 NNS denotes defects
T4426 422-425 CC denotes and
T4427 426-434 JJ denotes probable
T4428 435-442 NN denotes hypoxia
T4429 443-444 -LRB- denotes [
T4430 444-446 CD denotes 12
T4431 446-447 SYM denotes –
T4432 447-449 CD denotes 14
T4433 449-450 -RRB- denotes ]
T4434 450-451 . denotes .
T4435 451-543 sentence denotes Indeed, E2f3-induced apoptosis in fibroblasts has recently been shown to require E2f1 [15].
T4436 452-458 RB denotes Indeed
T4437 516-521 VBN denotes shown
T4438 458-460 , denotes ,
T4439 460-464 NN denotes E2f3
T4440 465-472 VBN denotes induced
T4441 464-465 HYPH denotes -
T4442 473-482 NN denotes apoptosis
T4443 483-485 IN denotes in
T4444 486-497 NNS denotes fibroblasts
T4445 498-501 VBZ denotes has
T4446 502-510 RB denotes recently
T4447 511-515 VBN denotes been
T4448 522-524 TO denotes to
T4449 525-532 VB denotes require
T4450 533-537 NN denotes E2f1
T4451 538-539 -LRB- denotes [
T4452 539-541 CD denotes 15
T4453 541-542 -RRB- denotes ]
T4454 542-543 . denotes .
T4455 543-632 sentence denotes Thus, it is controversial whether E2f3 is required for apoptosis of any Rb KO cell type.
T4456 544-548 RB denotes Thus
T4457 553-555 VBZ denotes is
T4458 548-550 , denotes ,
T4459 550-552 PRP denotes it
T4460 556-569 JJ denotes controversial
T4461 570-577 IN denotes whether
T4462 586-594 VBN denotes required
T4463 578-582 NN denotes E2f3
T4464 583-585 VBZ denotes is
T4465 595-598 IN denotes for
T4466 599-608 NN denotes apoptosis
T4467 609-611 IN denotes of
T4468 612-615 DT denotes any
T4469 627-631 NN denotes type
T4470 616-618 NN denotes Rb
T4471 619-621 NN denotes KO
T4472 622-626 NN denotes cell
T4473 631-632 . denotes .
T4474 632-826 sentence denotes Determining which activating E2fs promote death in distinct Rb KO tissues requires conditional rather than germ line models of Rb deletion to avoid secondary indirect effects (such as hypoxia).
T4475 633-644 VBG denotes Determining
T4476 707-715 VBZ denotes requires
T4477 645-650 WDT denotes which
T4478 662-666 NNS denotes E2fs
T4479 651-661 VBG denotes activating
T4480 667-674 VBP denotes promote
T4481 675-680 NN denotes death
T4482 681-683 IN denotes in
T4483 684-692 JJ denotes distinct
T4484 699-706 NNS denotes tissues
T4485 693-695 NN denotes Rb
T4486 696-698 NN denotes KO
T4487 716-727 JJ denotes conditional
T4488 750-756 NNS denotes models
T4489 728-734 RB denotes rather
T4490 735-739 IN denotes than
T4491 740-744 NN denotes germ
T4492 745-749 NN denotes line
T4493 757-759 IN denotes of
T4494 760-762 NN denotes Rb
T4495 763-771 NN denotes deletion
T4496 772-774 TO denotes to
T4497 775-780 VB denotes avoid
T4498 781-790 JJ denotes secondary
T4499 800-807 NNS denotes effects
T4500 791-799 JJ denotes indirect
T4501 808-809 -LRB- denotes (
T4502 809-813 JJ denotes such
T4503 814-816 IN denotes as
T4504 817-824 NN denotes hypoxia
T4505 824-825 -RRB- denotes )
T4506 825-826 . denotes .
R649 T4340 T4341 csubj Activating,promote
R651 T4342 T4340 dobj E2fs,Activating
R652 T4343 T4341 aux may,promote
R654 T4344 T4341 advmod also,promote
R655 T4345 T4341 dobj apoptosis,promote
R657 T4346 T4341 prep in,promote
R659 T4347 T4348 det the,retina
R660 T4348 T4346 pobj retina,in
R662 T4349 T4350 compound Rb,KO
R663 T4350 T4348 compound KO,retina
R664 T4351 T4352 punct (,1B
R665 T4352 T4341 parataxis 1B,promote
R667 T4353 T4352 compound Figure,1B
R668 T4354 T4352 punct ),1B
R669 T4355 T4341 punct .,promote
R671 T4357 T4358 advmod Originally,considered
R673 T4359 T4358 punct ", ",considered
R674 T4360 T4358 nsubjpass E2f1,considered
R676 T4361 T4358 auxpass was,considered
R677 T4362 T4363 det the,member
R678 T4363 T4358 oprd member,considered
R680 T4364 T4363 amod primary,member
R681 T4365 T4363 amod pro-apoptotic,member
R682 T4366 T4363 prep of,member
R684 T4367 T4368 det the,family
R685 T4368 T4366 pobj family,of
R686 T4369 T4370 punct [,10
R687 T4370 T4358 parataxis 10,considered
R690 T4371 T4370 punct ],10
R691 T4372 T4358 punct .,considered
R693 T4374 T4375 advmod However,reevaluated
R694 T4376 T4375 punct ", ",reevaluated
R696 T4377 T4378 det this,view
R697 T4378 T4375 nsubjpass view,reevaluated
R699 T4379 T4375 auxpass was,reevaluated
R700 T4380 T4381 advmod when,shown
R702 T4381 T4375 advcl shown,reevaluated
R703 T4382 T4381 nsubjpass it,shown
R704 T4383 T4381 auxpass was,shown
R705 T4384 T4385 mark that,rescues
R707 T4385 T4381 ccomp rescues,shown
R708 T4386 T4387 preconj either,E2f1
R709 T4387 T4388 nmod E2f1,deletion
R711 T4388 T4385 nsubj deletion,rescues
R712 T4389 T4387 cc or,E2f1
R713 T4390 T4387 conj E2f3,E2f1
R715 T4391 T4385 dobj apoptosis,rescues
R716 T4392 T4385 prep in,rescues
R717 T4393 T4394 det the,system
R719 T4394 T4392 pobj system,in
R720 T4395 T4394 amod developing,system
R721 T4396 T4394 amod central,system
R723 T4397 T4394 amod nervous,system
R724 T4398 T4394 punct (,system
R725 T4399 T4394 appos CNS,system
R726 T4400 T4394 punct ),system
R728 T4401 T4394 prep of,system
R729 T4402 T4403 compound Rb,KO
R730 T4403 T4404 compound KO,embryos
R731 T4404 T4401 pobj embryos,of
R733 T4405 T4406 punct [,11
R734 T4406 T4381 parataxis 11,shown
R735 T4407 T4406 nummod 6,11
R737 T4408 T4406 punct ",",11
R738 T4409 T4406 punct ],11
R739 T4410 T4375 punct .,reevaluated
R740 T4412 T4413 advmod Subsequently,shown
R742 T4414 T4413 punct ", ",shown
R743 T4415 T4416 compound CNS,apoptosis
R744 T4416 T4413 nsubjpass apoptosis,shown
R746 T4417 T4413 auxpass was,shown
R747 T4418 T4419 aux to,be
R748 T4419 T4413 xcomp be,shown
R750 T4420 T4421 det an,result
R751 T4421 T4419 attr result,be
R753 T4422 T4421 amod indirect,result
R754 T4423 T4421 prep of,result
R755 T4424 T4425 amod placental,defects
R757 T4425 T4423 pobj defects,of
R758 T4426 T4425 cc and,defects
R759 T4427 T4428 amod probable,hypoxia
R761 T4428 T4425 conj hypoxia,defects
R762 T4429 T4430 punct [,12
R763 T4430 T4419 parataxis 12,be
R765 T4431 T4432 punct –,14
R766 T4432 T4430 prep 14,12
R767 T4433 T4430 punct ],12
R770 T4434 T4413 punct .,shown
R772 T4436 T4437 advmod Indeed,shown
R774 T4438 T4437 punct ", ",shown
R775 T4439 T4440 npadvmod E2f3,induced
R777 T4440 T4442 amod induced,apoptosis
R778 T4441 T4440 punct -,induced
R779 T4442 T4437 nsubjpass apoptosis,shown
R781 T4443 T4442 prep in,apoptosis
R782 T4444 T4443 pobj fibroblasts,in
R784 T4445 T4437 aux has,shown
R785 T4446 T4437 advmod recently,shown
R786 T4447 T4437 auxpass been,shown
R788 T4448 T4449 aux to,require
R789 T4449 T4437 xcomp require,shown
R790 T4450 T4449 dobj E2f1,require
R791 T4451 T4452 punct [,15
R792 T4452 T4449 parataxis 15,require
R793 T4453 T4452 punct ],15
R795 T4454 T4437 punct .,shown
R796 T4456 T4457 advmod Thus,is
R798 T4458 T4457 punct ", ",is
R800 T4459 T4457 nsubj it,is
R801 T4460 T4457 acomp controversial,is
R802 T4461 T4462 mark whether,required
R804 T4462 T4457 ccomp required,is
R805 T4463 T4462 nsubjpass E2f3,required
R806 T4464 T4462 auxpass is,required
R808 T4465 T4462 prep for,required
R809 T4466 T4465 pobj apoptosis,for
R811 T4467 T4466 prep of,apoptosis
R812 T4468 T4469 det any,type
R813 T4469 T4467 pobj type,of
R815 T4470 T4471 compound Rb,KO
R816 T4471 T4469 compound KO,type
R817 T4472 T4469 compound cell,type
R818 T4473 T4457 punct .,is
R820 T4475 T4476 csubj Determining,requires
R824 T4477 T4478 det which,E2fs
R825 T4478 T4480 dep E2fs,promote
R826 T4479 T4478 amod activating,E2fs
R828 T4480 T4475 ccomp promote,Determining
R829 T4481 T4480 dobj death,promote
R830 T4482 T4480 prep in,promote
R832 T4483 T4484 amod distinct,tissues
R833 T4484 T4482 pobj tissues,in
R834 T4485 T4486 compound Rb,KO
R836 T4486 T4484 compound KO,tissues
R837 T4487 T4488 amod conditional,models
R839 T4488 T4476 dobj models,requires
R840 T4489 T4490 advmod rather,than
R841 T4490 T4487 cc than,conditional
R842 T4491 T4492 compound germ,line
R843 T4492 T4487 conj line,conditional
R844 T4493 T4488 prep of,models
R846 T4494 T4495 compound Rb,deletion
R847 T4495 T4493 pobj deletion,of
R848 T4496 T4497 aux to,avoid
R850 T4497 T4476 advcl avoid,requires
R851 T4498 T4499 amod secondary,effects
R852 T4499 T4497 dobj effects,avoid
R853 T4500 T4499 amod indirect,effects
R854 T4501 T4499 punct (,effects
R856 T4502 T4503 amod such,as
R857 T4503 T4499 prep as,effects
R858 T4504 T4503 pobj hypoxia,as
R860 T4505 T4476 punct ),requires
R861 T4506 T4476 punct .,requires

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3690 11-15 PR_EXT:E2F denotes E2fs
T3691 33-42 GO:0006915 denotes apoptosis
T3692 50-52 PR_EXT:000013773 denotes Rb
T3693 56-62 UBERON:0000966 denotes retina
T3694 88-92 PR_EXT:000006852 denotes E2f1
T3695 124-133 GO_PATO_EXT:apoptotic_process_or_quality denotes apoptotic
T3696 226-230 PR_EXT:000006852 denotes E2f1
T3697 234-238 PR_EXT:000006854 denotes E2f3
T3698 239-247 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T3699 248-255 SO_EXT:sequence_rescue_process denotes rescues
T3700 256-265 GO:0006915 denotes apoptosis
T3701 284-306 UBERON:0001017 denotes central nervous system
T3702 308-311 UBERON:0001017 denotes CNS
T3703 316-318 PR_EXT:000013773 denotes Rb
T3704 322-329 UBERON:0000922 denotes embryos
T3705 352-355 UBERON:0001017 denotes CNS
T3706 356-365 GO:0006915 denotes apoptosis
T3707 404-413 UBERON:0001987 denotes placental
T3708 460-464 PR_EXT:000006854 denotes E2f3
T3709 473-482 GO:0006915 denotes apoptosis
T3710 486-497 CL:0000057 denotes fibroblasts
T3711 533-537 PR_EXT:000006852 denotes E2f1
T3712 578-582 PR_EXT:000006854 denotes E2f3
T3713 599-608 GO:0006915 denotes apoptosis
T3714 616-618 PR_EXT:000013773 denotes Rb
T3715 622-626 CL_GO_EXT:cell denotes cell
T3716 662-666 PR_EXT:E2F denotes E2fs
T3717 675-680 GO:0016265 denotes death
T3718 693-695 PR_EXT:000013773 denotes Rb
T3719 699-706 UBERON:0000479 denotes tissues
T3720 760-762 PR_EXT:000013773 denotes Rb
T3721 763-771 SO_EXT:sequence_deletion_entity_or_process denotes deletion

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3436 33-42 GO:0006915 denotes apoptosis
T3437 50-52 PR:000013773 denotes Rb
T3438 56-62 UBERON:0000966 denotes retina
T3439 88-92 PR:000006852 denotes E2f1
T3440 226-230 PR:000006852 denotes E2f1
T3441 234-238 PR:000006854 denotes E2f3
T3442 256-265 GO:0006915 denotes apoptosis
T3443 284-306 UBERON:0001017 denotes central nervous system
T3444 308-311 UBERON:0001017 denotes CNS
T3445 316-318 PR:000013773 denotes Rb
T3446 322-329 UBERON:0000922 denotes embryos
T3447 352-355 UBERON:0001017 denotes CNS
T3448 356-365 GO:0006915 denotes apoptosis
T3449 404-413 UBERON:0001987 denotes placental
T3450 460-464 PR:000006854 denotes E2f3
T3451 473-482 GO:0006915 denotes apoptosis
T3452 486-497 CL:0000057 denotes fibroblasts
T3453 533-537 PR:000006852 denotes E2f1
T3454 578-582 PR:000006854 denotes E2f3
T3455 599-608 GO:0006915 denotes apoptosis
T3456 616-618 PR:000013773 denotes Rb
T3457 675-680 GO:0016265 denotes death
T3458 693-695 PR:000013773 denotes Rb
T3459 699-706 UBERON:0000479 denotes tissues
T3460 760-762 PR:000013773 denotes Rb

2_test

Id Subject Object Predicate Lexical cue
17608565-9207076-84868950 156-158 9207076 denotes 10
17608565-9774968-84868951 331-332 9774968 denotes 6
17608565-12944480-84868952 333-335 12944480 denotes 11
17608565-12607001-84868953 444-446 12607001 denotes 12
17608565-12093735-84868953 444-446 12093735 denotes 12
17608565-12529408-84868953 444-446 12529408 denotes 12
17608565-15976820-84868954 539-541 15976820 denotes 15
T38996 156-158 9207076 denotes 10
T39364 331-332 9774968 denotes 6
T81130 333-335 12944480 denotes 11
T45376 444-446 12607001 denotes 12
T63014 444-446 12093735 denotes 12
T12410 444-446 12529408 denotes 12
T63844 539-541 15976820 denotes 15