Id |
Subject |
Object |
Predicate |
Lexical cue |
T18779 |
109-114 |
VBN |
denotes |
shown |
T18780 |
100-104 |
NNS |
denotes |
data |
T18781 |
105-108 |
RB |
denotes |
not |
T18782 |
114-115 |
-RRB- |
denotes |
) |
T18783 |
115-116 |
. |
denotes |
. |
T18784 |
116-324 |
sentence |
denotes |
For example, in the P20 amygdala, E2f3 colocalized with the general neuronal markers Mtap2 and Mecp2 [52], but not with Calb2, which marks a subset of neurons, or with the glial marker Gfap (data not shown). |
T18785 |
117-120 |
IN |
denotes |
For |
T18786 |
156-167 |
VBD |
denotes |
colocalized |
T18787 |
121-128 |
NN |
denotes |
example |
T18788 |
128-130 |
, |
denotes |
, |
T18789 |
130-132 |
IN |
denotes |
in |
T18790 |
133-136 |
DT |
denotes |
the |
T18791 |
141-149 |
NN |
denotes |
amygdala |
T18792 |
137-140 |
NN |
denotes |
P20 |
T18793 |
149-151 |
, |
denotes |
, |
T18794 |
151-155 |
NN |
denotes |
E2f3 |
T18795 |
168-172 |
IN |
denotes |
with |
T18796 |
173-176 |
DT |
denotes |
the |
T18797 |
194-201 |
NNS |
denotes |
markers |
T18798 |
177-184 |
JJ |
denotes |
general |
T18799 |
185-193 |
JJ |
denotes |
neuronal |
T18800 |
202-207 |
NN |
denotes |
Mtap2 |
T18801 |
208-211 |
CC |
denotes |
and |
T18802 |
212-217 |
NN |
denotes |
Mecp2 |
T18803 |
218-219 |
-LRB- |
denotes |
[ |
T18804 |
219-221 |
CD |
denotes |
52 |
T18805 |
221-222 |
-RRB- |
denotes |
] |
T18806 |
222-224 |
, |
denotes |
, |
T18807 |
224-227 |
CC |
denotes |
but |
T18808 |
228-231 |
RB |
denotes |
not |
T18809 |
232-236 |
IN |
denotes |
with |
T18810 |
237-242 |
NN |
denotes |
Calb2 |
T18811 |
242-244 |
, |
denotes |
, |
T18812 |
244-249 |
WDT |
denotes |
which |
T18813 |
250-255 |
VBZ |
denotes |
marks |
T18814 |
256-257 |
DT |
denotes |
a |
T18815 |
258-264 |
NN |
denotes |
subset |
T18816 |
265-267 |
IN |
denotes |
of |
T18817 |
268-275 |
NNS |
denotes |
neurons |
T18818 |
275-277 |
, |
denotes |
, |
T18819 |
277-279 |
CC |
denotes |
or |
T18820 |
280-284 |
IN |
denotes |
with |
T18821 |
285-288 |
DT |
denotes |
the |
T18822 |
295-301 |
NN |
denotes |
marker |
T18823 |
289-294 |
JJ |
denotes |
glial |
T18824 |
302-306 |
NN |
denotes |
Gfap |
T18825 |
307-308 |
-LRB- |
denotes |
( |
T18826 |
317-322 |
VBN |
denotes |
shown |
T18827 |
308-312 |
NNS |
denotes |
data |
T18828 |
313-316 |
RB |
denotes |
not |
T18829 |
322-323 |
-RRB- |
denotes |
) |
T18830 |
323-324 |
. |
denotes |
. |
T18831 |
324-488 |
sentence |
denotes |
Unlike in retinal SACs, E2f3 was not coexpressed in Chat+ or Slc18a3+ cholinergic neurons located in various regions of the brain and spinal cord (data not shown). |
T18832 |
325-331 |
IN |
denotes |
Unlike |
T18833 |
362-373 |
VBN |
denotes |
coexpressed |
T18834 |
332-334 |
IN |
denotes |
in |
T18835 |
335-342 |
JJ |
denotes |
retinal |
T18836 |
343-347 |
NNS |
denotes |
SACs |
T18837 |
347-349 |
, |
denotes |
, |
T18838 |
349-353 |
NN |
denotes |
E2f3 |
T18839 |
354-357 |
VBD |
denotes |
was |
T18840 |
358-361 |
RB |
denotes |
not |
T18841 |
374-376 |
IN |
denotes |
in |
T18842 |
377-381 |
NN |
denotes |
Chat |
T18843 |
407-414 |
NNS |
denotes |
neurons |
T18844 |
381-382 |
SYM |
denotes |
+ |
T18845 |
383-385 |
CC |
denotes |
or |
T18846 |
386-393 |
NN |
denotes |
Slc18a3 |
T18847 |
393-394 |
SYM |
denotes |
+ |
T18848 |
395-406 |
JJ |
denotes |
cholinergic |
T18849 |
415-422 |
VBN |
denotes |
located |
T18850 |
423-425 |
IN |
denotes |
in |
T18851 |
426-433 |
JJ |
denotes |
various |
T18852 |
434-441 |
NNS |
denotes |
regions |
T18853 |
442-444 |
IN |
denotes |
of |
T18854 |
445-448 |
DT |
denotes |
the |
T18855 |
449-454 |
NN |
denotes |
brain |
T18856 |
455-458 |
CC |
denotes |
and |
T18857 |
459-465 |
JJ |
denotes |
spinal |
T18858 |
466-470 |
NN |
denotes |
cord |
T18859 |
471-472 |
-LRB- |
denotes |
( |
T18860 |
481-486 |
VBN |
denotes |
shown |
T18861 |
472-476 |
NNS |
denotes |
data |
T18862 |
477-480 |
RB |
denotes |
not |
T18863 |
486-487 |
-RRB- |
denotes |
) |
T18864 |
487-488 |
. |
denotes |
. |
T18865 |
488-699 |
sentence |
denotes |
In agreement, we could not detect defects in cholinergic Rb KO neurons in the developing forebrain, but other Rb KO neurons in this region showed differentiation defects that were rescued by deleting E2f3 [53]. |
T18866 |
489-491 |
IN |
denotes |
In |
T18867 |
516-522 |
VB |
denotes |
detect |
T18868 |
492-501 |
NN |
denotes |
agreement |
T18869 |
501-503 |
, |
denotes |
, |
T18870 |
503-505 |
PRP |
denotes |
we |
T18871 |
506-511 |
MD |
denotes |
could |
T18872 |
512-515 |
RB |
denotes |
not |
T18873 |
523-530 |
NNS |
denotes |
defects |
T18874 |
531-533 |
IN |
denotes |
in |
T18875 |
534-545 |
JJ |
denotes |
cholinergic |
T18876 |
552-559 |
NNS |
denotes |
neurons |
T18877 |
546-548 |
NN |
denotes |
Rb |
T18878 |
549-551 |
NN |
denotes |
KO |
T18879 |
560-562 |
IN |
denotes |
in |
T18880 |
563-566 |
DT |
denotes |
the |
T18881 |
578-587 |
NN |
denotes |
forebrain |
T18882 |
567-577 |
VBG |
denotes |
developing |
T18883 |
587-589 |
, |
denotes |
, |
T18884 |
589-592 |
CC |
denotes |
but |
T18885 |
593-598 |
JJ |
denotes |
other |
T18886 |
605-612 |
NNS |
denotes |
neurons |
T18887 |
599-601 |
NN |
denotes |
Rb |
T18888 |
602-604 |
NN |
denotes |
KO |
T18889 |
628-634 |
VBD |
denotes |
showed |
T18890 |
613-615 |
IN |
denotes |
in |
T18891 |
616-620 |
DT |
denotes |
this |
T18892 |
621-627 |
NN |
denotes |
region |
T18893 |
635-650 |
NN |
denotes |
differentiation |
T18894 |
651-658 |
NNS |
denotes |
defects |
T18895 |
659-663 |
WDT |
denotes |
that |
T18896 |
669-676 |
VBN |
denotes |
rescued |
T18897 |
664-668 |
VBD |
denotes |
were |
T18898 |
677-679 |
IN |
denotes |
by |
T18899 |
680-688 |
VBG |
denotes |
deleting |
T18900 |
689-693 |
NN |
denotes |
E2f3 |
T18901 |
694-695 |
-LRB- |
denotes |
[ |
T18902 |
695-697 |
CD |
denotes |
53 |
T18903 |
697-698 |
-RRB- |
denotes |
] |
T18904 |
698-699 |
. |
denotes |
. |
T18905 |
699-829 |
sentence |
denotes |
Together, these results suggest that the common mechanism by which Rb promotes neural differentiation is through E2f3 inhibition. |
T18906 |
700-708 |
RB |
denotes |
Together |
T18907 |
724-731 |
VBP |
denotes |
suggest |
T18908 |
708-710 |
, |
denotes |
, |
T18909 |
710-715 |
DT |
denotes |
these |
T18910 |
716-723 |
NNS |
denotes |
results |
T18911 |
732-736 |
IN |
denotes |
that |
T18912 |
802-804 |
VBZ |
denotes |
is |
T18913 |
737-740 |
DT |
denotes |
the |
T18914 |
748-757 |
NN |
denotes |
mechanism |
T18915 |
741-747 |
JJ |
denotes |
common |
T18916 |
758-760 |
IN |
denotes |
by |
T18917 |
770-778 |
VBZ |
denotes |
promotes |
T18918 |
761-766 |
WDT |
denotes |
which |
T18919 |
767-769 |
NN |
denotes |
Rb |
T18920 |
779-785 |
JJ |
denotes |
neural |
T18921 |
786-801 |
NN |
denotes |
differentiation |
T18922 |
805-812 |
IN |
denotes |
through |
T18923 |
813-817 |
NN |
denotes |
E2f3 |
T18924 |
818-828 |
NN |
denotes |
inhibition |
T18925 |
828-829 |
. |
denotes |
. |
T18770 |
40-48 |
JJ |
denotes |
specific |
T18771 |
56-58 |
IN |
denotes |
of |
T18772 |
59-65 |
JJ |
denotes |
mature |
T18773 |
66-73 |
NNS |
denotes |
neurons |
T18774 |
74-76 |
IN |
denotes |
in |
T18775 |
77-84 |
JJ |
denotes |
various |
T18776 |
91-98 |
NNS |
denotes |
regions |
T18777 |
85-90 |
NN |
denotes |
brain |
T18778 |
99-100 |
-LRB- |
denotes |
( |
T18760 |
0-2 |
PRP |
denotes |
We |
T18761 |
8-13 |
VBD |
denotes |
found |
T18762 |
3-7 |
RB |
denotes |
also |
T18763 |
14-18 |
IN |
denotes |
that |
T18764 |
24-26 |
VBZ |
denotes |
is |
T18765 |
19-23 |
NN |
denotes |
E2f3 |
T18766 |
27-34 |
JJ |
denotes |
present |
T18767 |
35-37 |
IN |
denotes |
in |
T18768 |
38-39 |
DT |
denotes |
a |
T18769 |
49-55 |
NN |
denotes |
subset |
R5587 |
T18785 |
T18786 |
prep |
For,colocalized |
R5588 |
T18787 |
T18785 |
pobj |
example,For |
R5589 |
T18788 |
T18786 |
punct |
", ",colocalized |
R5590 |
T18789 |
T18786 |
prep |
in,colocalized |
R5591 |
T18790 |
T18791 |
det |
the,amygdala |
R5592 |
T18791 |
T18789 |
pobj |
amygdala,in |
R5593 |
T18792 |
T18791 |
compound |
P20,amygdala |
R5594 |
T18793 |
T18786 |
punct |
", ",colocalized |
R5595 |
T18794 |
T18786 |
nsubj |
E2f3,colocalized |
R5596 |
T18795 |
T18786 |
prep |
with,colocalized |
R5597 |
T18796 |
T18797 |
det |
the,markers |
R5598 |
T18797 |
T18795 |
pobj |
markers,with |
R5599 |
T18798 |
T18797 |
amod |
general,markers |
R5600 |
T18799 |
T18797 |
amod |
neuronal,markers |
R5601 |
T18800 |
T18797 |
appos |
Mtap2,markers |
R5602 |
T18801 |
T18800 |
cc |
and,Mtap2 |
R5603 |
T18802 |
T18800 |
conj |
Mecp2,Mtap2 |
R5604 |
T18803 |
T18804 |
punct |
[,52 |
R5605 |
T18804 |
T18797 |
parataxis |
52,markers |
R5606 |
T18805 |
T18804 |
punct |
],52 |
R5607 |
T18806 |
T18795 |
punct |
", ",with |
R5608 |
T18807 |
T18795 |
cc |
but,with |
R5609 |
T18808 |
T18807 |
neg |
not,but |
R5610 |
T18809 |
T18795 |
conj |
with,with |
R5611 |
T18810 |
T18809 |
pobj |
Calb2,with |
R5612 |
T18811 |
T18810 |
punct |
", ",Calb2 |
R5613 |
T18812 |
T18813 |
dep |
which,marks |
R5614 |
T18813 |
T18810 |
relcl |
marks,Calb2 |
R5615 |
T18814 |
T18815 |
det |
a,subset |
R5616 |
T18815 |
T18813 |
dobj |
subset,marks |
R5617 |
T18816 |
T18815 |
prep |
of,subset |
R5618 |
T18817 |
T18816 |
pobj |
neurons,of |
R5619 |
T18818 |
T18809 |
punct |
", ",with |
R5620 |
T18819 |
T18809 |
cc |
or,with |
R5621 |
T18820 |
T18809 |
conj |
with,with |
R5622 |
T18821 |
T18822 |
det |
the,marker |
R5623 |
T18822 |
T18820 |
pobj |
marker,with |
R5624 |
T18823 |
T18822 |
amod |
glial,marker |
R5625 |
T18824 |
T18822 |
appos |
Gfap,marker |
R5626 |
T18825 |
T18826 |
punct |
(,shown |
R5627 |
T18826 |
T18786 |
parataxis |
shown,colocalized |
R5628 |
T18827 |
T18826 |
nsubj |
data,shown |
R5629 |
T18828 |
T18826 |
neg |
not,shown |
R5630 |
T18829 |
T18826 |
punct |
),shown |
R5631 |
T18830 |
T18786 |
punct |
.,colocalized |
R5632 |
T18832 |
T18833 |
prep |
Unlike,coexpressed |
R5633 |
T18834 |
T18832 |
prep |
in,Unlike |
R5634 |
T18835 |
T18836 |
amod |
retinal,SACs |
R5635 |
T18836 |
T18834 |
pobj |
SACs,in |
R5636 |
T18837 |
T18833 |
punct |
", ",coexpressed |
R5637 |
T18838 |
T18833 |
nsubjpass |
E2f3,coexpressed |
R5638 |
T18839 |
T18833 |
auxpass |
was,coexpressed |
R5639 |
T18840 |
T18833 |
neg |
not,coexpressed |
R5640 |
T18841 |
T18833 |
prep |
in,coexpressed |
R5641 |
T18842 |
T18843 |
nmod |
Chat,neurons |
R5642 |
T18843 |
T18841 |
pobj |
neurons,in |
R5643 |
T18844 |
T18842 |
punct |
+,Chat |
R5644 |
T18845 |
T18842 |
cc |
or,Chat |
R5645 |
T18846 |
T18842 |
conj |
Slc18a3,Chat |
R5646 |
T18847 |
T18846 |
punct |
+,Slc18a3 |
R5647 |
T18848 |
T18843 |
amod |
cholinergic,neurons |
R5648 |
T18849 |
T18843 |
acl |
located,neurons |
R5649 |
T18850 |
T18849 |
prep |
in,located |
R5650 |
T18851 |
T18852 |
amod |
various,regions |
R5651 |
T18852 |
T18850 |
pobj |
regions,in |
R5652 |
T18853 |
T18852 |
prep |
of,regions |
R5653 |
T18854 |
T18855 |
det |
the,brain |
R5654 |
T18855 |
T18853 |
pobj |
brain,of |
R5655 |
T18856 |
T18855 |
cc |
and,brain |
R5656 |
T18857 |
T18858 |
amod |
spinal,cord |
R5657 |
T18858 |
T18855 |
conj |
cord,brain |
R5658 |
T18859 |
T18860 |
punct |
(,shown |
R5659 |
T18860 |
T18833 |
parataxis |
shown,coexpressed |
R5660 |
T18861 |
T18860 |
nsubj |
data,shown |
R5661 |
T18862 |
T18860 |
neg |
not,shown |
R5662 |
T18863 |
T18860 |
punct |
),shown |
R5663 |
T18864 |
T18833 |
punct |
.,coexpressed |
R5664 |
T18866 |
T18867 |
prep |
In,detect |
R5665 |
T18868 |
T18866 |
pobj |
agreement,In |
R5666 |
T18869 |
T18867 |
punct |
", ",detect |
R5667 |
T18870 |
T18867 |
nsubj |
we,detect |
R5668 |
T18871 |
T18867 |
aux |
could,detect |
R5669 |
T18872 |
T18867 |
neg |
not,detect |
R5670 |
T18873 |
T18867 |
dobj |
defects,detect |
R5671 |
T18874 |
T18873 |
prep |
in,defects |
R5672 |
T18875 |
T18876 |
amod |
cholinergic,neurons |
R5673 |
T18876 |
T18874 |
pobj |
neurons,in |
R5674 |
T18877 |
T18878 |
compound |
Rb,KO |
R5675 |
T18878 |
T18876 |
compound |
KO,neurons |
R5676 |
T18879 |
T18876 |
prep |
in,neurons |
R5677 |
T18880 |
T18881 |
det |
the,forebrain |
R5678 |
T18881 |
T18879 |
pobj |
forebrain,in |
R5679 |
T18882 |
T18881 |
amod |
developing,forebrain |
R5680 |
T18883 |
T18867 |
punct |
", ",detect |
R5681 |
T18884 |
T18867 |
cc |
but,detect |
R5682 |
T18885 |
T18886 |
amod |
other,neurons |
R5683 |
T18886 |
T18889 |
nsubj |
neurons,showed |
R5684 |
T18887 |
T18888 |
compound |
Rb,KO |
R5685 |
T18888 |
T18886 |
compound |
KO,neurons |
R5686 |
T18889 |
T18867 |
conj |
showed,detect |
R5687 |
T18890 |
T18886 |
prep |
in,neurons |
R5688 |
T18891 |
T18892 |
det |
this,region |
R5689 |
T18892 |
T18890 |
pobj |
region,in |
R5690 |
T18893 |
T18894 |
compound |
differentiation,defects |
R5691 |
T18894 |
T18889 |
dobj |
defects,showed |
R5692 |
T18895 |
T18896 |
dep |
that,rescued |
R5693 |
T18896 |
T18894 |
relcl |
rescued,defects |
R5694 |
T18897 |
T18896 |
auxpass |
were,rescued |
R5695 |
T18898 |
T18896 |
prep |
by,rescued |
R5696 |
T18899 |
T18898 |
pcomp |
deleting,by |
R5697 |
T18900 |
T18899 |
dobj |
E2f3,deleting |
R5698 |
T18901 |
T18902 |
punct |
[,53 |
R5699 |
T18902 |
T18889 |
parataxis |
53,showed |
R5700 |
T18903 |
T18902 |
punct |
],53 |
R5701 |
T18904 |
T18889 |
punct |
.,showed |
R5702 |
T18906 |
T18907 |
advmod |
Together,suggest |
R5703 |
T18908 |
T18907 |
punct |
", ",suggest |
R5704 |
T18909 |
T18910 |
det |
these,results |
R5705 |
T18910 |
T18907 |
nsubj |
results,suggest |
R5706 |
T18911 |
T18912 |
mark |
that,is |
R5707 |
T18912 |
T18907 |
ccomp |
is,suggest |
R5708 |
T18913 |
T18914 |
det |
the,mechanism |
R5709 |
T18914 |
T18912 |
nsubj |
mechanism,is |
R5710 |
T18915 |
T18914 |
amod |
common,mechanism |
R5711 |
T18916 |
T18917 |
prep |
by,promotes |
R5712 |
T18917 |
T18914 |
relcl |
promotes,mechanism |
R5713 |
T18918 |
T18916 |
pobj |
which,by |
R5714 |
T18919 |
T18917 |
nsubj |
Rb,promotes |
R5715 |
T18920 |
T18921 |
amod |
neural,differentiation |
R5716 |
T18921 |
T18917 |
dobj |
differentiation,promotes |
R5717 |
T18922 |
T18912 |
prep |
through,is |
R5718 |
T18923 |
T18924 |
compound |
E2f3,inhibition |
R5719 |
T18924 |
T18922 |
pobj |
inhibition,through |
R5720 |
T18925 |
T18907 |
punct |
.,suggest |
R5564 |
T18760 |
T18761 |
nsubj |
We,found |
R5565 |
T18762 |
T18761 |
advmod |
also,found |
R5566 |
T18763 |
T18764 |
mark |
that,is |
R5567 |
T18764 |
T18761 |
ccomp |
is,found |
R5568 |
T18765 |
T18764 |
nsubj |
E2f3,is |
R5569 |
T18766 |
T18764 |
acomp |
present,is |
R5570 |
T18767 |
T18764 |
prep |
in,is |
R5571 |
T18768 |
T18769 |
det |
a,subset |
R5572 |
T18769 |
T18767 |
pobj |
subset,in |
R5573 |
T18770 |
T18769 |
amod |
specific,subset |
R5574 |
T18771 |
T18769 |
prep |
of,subset |
R5575 |
T18772 |
T18773 |
amod |
mature,neurons |
R5576 |
T18773 |
T18771 |
pobj |
neurons,of |
R5577 |
T18774 |
T18769 |
prep |
in,subset |
R5578 |
T18775 |
T18776 |
amod |
various,regions |
R5579 |
T18776 |
T18774 |
pobj |
regions,in |
R5580 |
T18777 |
T18776 |
compound |
brain,regions |
R5581 |
T18778 |
T18779 |
punct |
(,shown |
R5582 |
T18779 |
T18764 |
parataxis |
shown,is |
R5583 |
T18780 |
T18779 |
nsubj |
data,shown |
R5584 |
T18781 |
T18779 |
neg |
not,shown |
R5585 |
T18782 |
T18779 |
punct |
),shown |
R5586 |
T18783 |
T18761 |
punct |
.,found |