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PMC:1914394 / 22738-23683 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T13766 0-4 NNS denotes ERGs
T13767 15-21 VBP denotes assess
T13768 5-14 RB denotes primarily
T13769 22-35 NN denotes photoreceptor
T13770 53-61 NN denotes function
T13771 36-39 CC denotes and
T13772 40-47 JJ denotes bipolar
T13773 48-52 NN denotes cell
T13774 61-63 , denotes ,
T13775 63-66 CC denotes but
T13776 67-70 MD denotes may
T13777 71-75 VB denotes miss
T13778 76-91 NN denotes differentiation
T13779 92-99 NNS denotes defects
T13780 100-102 IN denotes in
T13781 103-108 JJ denotes other
T13782 109-114 NNS denotes cells
T13783 114-115 . denotes .
T13784 115-208 sentence denotes To test for subtle differences we stained the Rb/E2f1 DKO retina with 43 markers (Table S1).
T13785 116-118 TO denotes To
T13786 119-123 VB denotes test
T13787 150-157 VBD denotes stained
T13788 124-127 IN denotes for
T13789 128-134 JJ denotes subtle
T13790 135-146 NNS denotes differences
T13791 147-149 PRP denotes we
T13792 158-161 DT denotes the
T13793 174-180 NN denotes retina
T13794 162-164 NN denotes Rb
T13795 165-169 NN denotes E2f1
T13796 164-165 HYPH denotes /
T13797 170-173 NN denotes DKO
T13798 181-185 IN denotes with
T13799 186-188 CD denotes 43
T13800 189-196 NNS denotes markers
T13801 197-198 -LRB- denotes (
T13802 204-206 NN denotes S1
T13803 198-203 NN denotes Table
T13804 206-207 -RRB- denotes )
T13805 207-208 . denotes .
T13806 208-308 sentence denotes Thirty-two proteins displayed identical patterns in WT, E2f1 KO, and Rb/E2f1 DKO retina (Table S1).
T13807 209-215 CD denotes Thirty
T13808 216-219 CD denotes two
T13809 215-216 HYPH denotes -
T13810 220-228 NN denotes proteins
T13811 229-238 VBD denotes displayed
T13812 239-248 JJ denotes identical
T13813 249-257 NNS denotes patterns
T13814 258-260 IN denotes in
T13815 261-263 NN denotes WT
T13816 290-296 NN denotes retina
T13817 263-265 , denotes ,
T13818 265-269 NN denotes E2f1
T13819 270-272 NN denotes KO
T13820 272-274 , denotes ,
T13821 274-277 CC denotes and
T13822 278-280 NN denotes Rb
T13823 281-285 NN denotes E2f1
T13824 280-281 HYPH denotes /
T13825 286-289 NN denotes DKO
T13826 297-298 -LRB- denotes (
T13827 304-306 NN denotes S1
T13828 298-303 NN denotes Table
T13829 306-307 -RRB- denotes )
T13830 307-308 . denotes .
T13831 308-410 sentence denotes The other 11 markers revealed a cell-cycle– and apoptosis-independent differentiation defect in SACs.
T13832 309-312 DT denotes The
T13833 322-329 NNS denotes markers
T13834 313-318 JJ denotes other
T13835 319-321 CD denotes 11
T13836 330-338 VBD denotes revealed
T13837 339-340 DT denotes a
T13838 395-401 NN denotes defect
T13839 341-345 NN denotes cell
T13840 346-351 NN denotes cycle
T13841 345-346 HYPH denotes -
T13842 367-378 JJ denotes independent
T13843 351-352 HYPH denotes –
T13844 353-356 CC denotes and
T13845 357-366 NN denotes apoptosis
T13846 366-367 HYPH denotes -
T13847 379-394 NN denotes differentiation
T13848 402-404 IN denotes in
T13849 405-409 NNS denotes SACs
T13850 409-410 . denotes .
T13851 410-586 sentence denotes We first studied Calb2 (calretinin), which marks a subset of amacrine and ganglion cell bodies as well as three tracks corresponding to their processes in the IPL (Figure 3A).
T13852 411-413 PRP denotes We
T13853 420-427 VBD denotes studied
T13854 414-419 RB denotes first
T13855 428-433 NN denotes Calb2
T13856 434-435 -LRB- denotes (
T13857 435-445 NN denotes calretinin
T13858 445-446 -RRB- denotes )
T13859 446-448 , denotes ,
T13860 448-453 WDT denotes which
T13861 454-459 VBZ denotes marks
T13862 460-461 DT denotes a
T13863 462-468 NN denotes subset
T13864 469-471 IN denotes of
T13865 472-480 JJ denotes amacrine
T13866 499-505 NNS denotes bodies
T13867 481-484 CC denotes and
T13868 485-493 NN denotes ganglion
T13869 494-498 NN denotes cell
T13870 506-508 RB denotes as
T13871 514-516 IN denotes as
T13872 509-513 RB denotes well
T13873 517-522 CD denotes three
T13874 523-529 NNS denotes tracks
T13875 530-543 VBG denotes corresponding
T13876 544-546 IN denotes to
T13877 547-552 PRP$ denotes their
T13878 553-562 NNS denotes processes
T13879 563-565 IN denotes in
T13880 566-569 DT denotes the
T13881 570-573 NN denotes IPL
T13882 574-575 -LRB- denotes (
T13883 582-584 NN denotes 3A
T13884 575-581 NN denotes Figure
T13885 584-585 -RRB- denotes )
T13886 585-586 . denotes .
T13887 586-654 sentence denotes Normal Calb2 staining was seen in the E2f1 KO IPL (data not shown).
T13888 587-593 JJ denotes Normal
T13889 600-608 NN denotes staining
T13890 594-599 NN denotes Calb2
T13891 613-617 VBN denotes seen
T13892 609-612 VBD denotes was
T13893 618-620 IN denotes in
T13894 621-624 DT denotes the
T13895 633-636 NN denotes IPL
T13896 625-629 NN denotes E2f1
T13897 630-632 NN denotes KO
T13898 637-638 -LRB- denotes (
T13899 647-652 VBN denotes shown
T13900 638-642 NNS denotes data
T13901 643-646 RB denotes not
T13902 652-653 -RRB- denotes )
T13903 653-654 . denotes .
T13904 654-786 sentence denotes However, only one Calb2+ track was evident in the Rb KO IPL, and this defect was not rescued in the Rb/E2f1 DKO retina (Figure 3A).
T13905 655-662 RB denotes However
T13906 686-689 VBD denotes was
T13907 662-664 , denotes ,
T13908 664-668 RB denotes only
T13909 680-685 NN denotes track
T13910 669-672 CD denotes one
T13911 673-678 NN denotes Calb2
T13912 678-679 SYM denotes +
T13913 690-697 JJ denotes evident
T13914 698-700 IN denotes in
T13915 701-704 DT denotes the
T13916 711-714 NN denotes IPL
T13917 705-707 NN denotes Rb
T13918 708-710 NN denotes KO
T13919 714-716 , denotes ,
T13920 716-719 CC denotes and
T13921 720-724 DT denotes this
T13922 725-731 NN denotes defect
T13923 740-747 VBN denotes rescued
T13924 732-735 VBD denotes was
T13925 736-739 RB denotes not
T13926 748-750 IN denotes in
T13927 751-754 DT denotes the
T13928 767-773 NN denotes retina
T13929 755-757 NN denotes Rb
T13930 758-762 NN denotes E2f1
T13931 757-758 HYPH denotes /
T13932 763-766 NN denotes DKO
T13933 774-775 -LRB- denotes (
T13934 782-784 NN denotes 3A
T13935 775-781 NN denotes Figure
T13936 784-785 -RRB- denotes )
T13937 785-786 . denotes .
T13938 786-945 sentence denotes We quantified Calb2+ cell bodies in the Rb KO INL (corresponding to amacrine cell staining only) and observed a reduction from P8 onwards (Figures 3C and S6).
T13939 787-789 PRP denotes We
T13940 790-800 VBD denotes quantified
T13941 801-806 NN denotes Calb2
T13942 813-819 NNS denotes bodies
T13943 806-807 SYM denotes +
T13944 808-812 NN denotes cell
T13945 820-822 IN denotes in
T13946 823-826 DT denotes the
T13947 833-836 NN denotes INL
T13948 827-829 NN denotes Rb
T13949 830-832 NN denotes KO
T13950 837-838 -LRB- denotes (
T13951 838-851 VBG denotes corresponding
T13952 852-854 IN denotes to
T13953 855-863 JJ denotes amacrine
T13954 864-868 NN denotes cell
T13955 869-877 NN denotes staining
T13956 878-882 RB denotes only
T13957 882-883 -RRB- denotes )
T13958 884-887 CC denotes and
T13959 888-896 VBD denotes observed
T13960 897-898 DT denotes a
T13961 899-908 NN denotes reduction
T13962 909-913 IN denotes from
T13963 914-916 NN denotes P8
T13964 917-924 RB denotes onwards
T13965 925-926 -LRB- denotes (
T13966 934-936 NN denotes 3C
T13967 926-933 NNS denotes Figures
T13968 937-940 CC denotes and
T13969 941-943 NN denotes S6
T13970 943-944 -RRB- denotes )
T13971 944-945 . denotes .
R3534 T13766 T13767 nsubj ERGs,assess
R3535 T13768 T13767 advmod primarily,assess
R3536 T13769 T13770 nmod photoreceptor,function
R3537 T13770 T13767 dobj function,assess
R3538 T13771 T13769 cc and,photoreceptor
R3539 T13772 T13773 amod bipolar,cell
R3540 T13773 T13769 conj cell,photoreceptor
R3541 T13774 T13767 punct ", ",assess
R3542 T13775 T13767 cc but,assess
R3543 T13776 T13777 aux may,miss
R3544 T13777 T13767 conj miss,assess
R3545 T13778 T13779 compound differentiation,defects
R3546 T13779 T13777 dobj defects,miss
R3547 T13780 T13777 prep in,miss
R3548 T13781 T13782 amod other,cells
R3549 T13782 T13780 pobj cells,in
R3550 T13783 T13767 punct .,assess
R3551 T13785 T13786 aux To,test
R3552 T13786 T13787 advcl test,stained
R3553 T13788 T13786 prep for,test
R3554 T13789 T13790 amod subtle,differences
R3555 T13790 T13788 pobj differences,for
R3556 T13791 T13787 nsubj we,stained
R3557 T13792 T13793 det the,retina
R3558 T13793 T13787 dobj retina,stained
R3559 T13794 T13795 compound Rb,E2f1
R3560 T13795 T13797 compound E2f1,DKO
R3561 T13796 T13795 punct /,E2f1
R3562 T13797 T13793 compound DKO,retina
R3563 T13798 T13787 prep with,stained
R3564 T13799 T13800 nummod 43,markers
R3565 T13800 T13798 pobj markers,with
R3566 T13801 T13802 punct (,S1
R3567 T13802 T13787 parataxis S1,stained
R3568 T13803 T13802 compound Table,S1
R3569 T13804 T13802 punct ),S1
R3570 T13805 T13787 punct .,stained
R3571 T13807 T13808 compound Thirty,two
R3572 T13808 T13810 nummod two,proteins
R3573 T13809 T13808 punct -,two
R3574 T13810 T13811 nsubj proteins,displayed
R3575 T13812 T13813 amod identical,patterns
R3576 T13813 T13811 dobj patterns,displayed
R3577 T13814 T13811 prep in,displayed
R3578 T13815 T13816 nmod WT,retina
R3579 T13816 T13814 pobj retina,in
R3580 T13817 T13815 punct ", ",WT
R3581 T13818 T13819 compound E2f1,KO
R3582 T13819 T13815 conj KO,WT
R3583 T13820 T13819 punct ", ",KO
R3584 T13821 T13819 cc and,KO
R3585 T13822 T13823 compound Rb,E2f1
R3586 T13823 T13825 compound E2f1,DKO
R3587 T13824 T13823 punct /,E2f1
R3588 T13825 T13819 conj DKO,KO
R3589 T13826 T13827 punct (,S1
R3590 T13827 T13811 parataxis S1,displayed
R3591 T13828 T13827 compound Table,S1
R3592 T13829 T13827 punct ),S1
R3593 T13830 T13811 punct .,displayed
R3594 T13832 T13833 det The,markers
R3595 T13833 T13836 nsubj markers,revealed
R3596 T13834 T13833 amod other,markers
R3597 T13835 T13833 nummod 11,markers
R3598 T13837 T13838 det a,defect
R3599 T13838 T13836 dobj defect,revealed
R3600 T13839 T13840 compound cell,cycle
R3601 T13840 T13842 npadvmod cycle,independent
R3602 T13841 T13840 punct -,cycle
R3603 T13842 T13838 amod independent,defect
R3604 T13843 T13840 punct –,cycle
R3605 T13844 T13840 cc and,cycle
R3606 T13845 T13840 conj apoptosis,cycle
R3607 T13846 T13842 punct -,independent
R3608 T13847 T13838 compound differentiation,defect
R3609 T13848 T13836 prep in,revealed
R3610 T13849 T13848 pobj SACs,in
R3611 T13850 T13836 punct .,revealed
R3612 T13852 T13853 nsubj We,studied
R3613 T13854 T13853 advmod first,studied
R3614 T13855 T13853 dobj Calb2,studied
R3615 T13856 T13855 punct (,Calb2
R3616 T13857 T13855 appos calretinin,Calb2
R3617 T13858 T13855 punct ),Calb2
R3618 T13859 T13855 punct ", ",Calb2
R3619 T13860 T13861 dep which,marks
R3620 T13861 T13855 relcl marks,Calb2
R3621 T13862 T13863 det a,subset
R3622 T13863 T13861 dobj subset,marks
R3623 T13864 T13863 prep of,subset
R3624 T13865 T13866 amod amacrine,bodies
R3625 T13866 T13864 pobj bodies,of
R3626 T13867 T13865 cc and,amacrine
R3627 T13868 T13869 compound ganglion,cell
R3628 T13869 T13865 conj cell,amacrine
R3629 T13870 T13871 advmod as,as
R3630 T13871 T13863 cc as,subset
R3631 T13872 T13871 advmod well,as
R3632 T13873 T13874 nummod three,tracks
R3633 T13874 T13863 conj tracks,subset
R3634 T13875 T13874 acl corresponding,tracks
R3635 T13876 T13875 prep to,corresponding
R3636 T13877 T13878 poss their,processes
R3637 T13878 T13876 pobj processes,to
R3638 T13879 T13878 prep in,processes
R3639 T13880 T13881 det the,IPL
R3640 T13881 T13879 pobj IPL,in
R3641 T13882 T13883 punct (,3A
R3642 T13883 T13861 parataxis 3A,marks
R3643 T13884 T13883 compound Figure,3A
R3644 T13885 T13883 punct ),3A
R3645 T13886 T13853 punct .,studied
R3646 T13888 T13889 amod Normal,staining
R3647 T13889 T13891 nsubjpass staining,seen
R3648 T13890 T13889 compound Calb2,staining
R3649 T13892 T13891 auxpass was,seen
R3650 T13893 T13891 prep in,seen
R3651 T13894 T13895 det the,IPL
R3652 T13895 T13893 pobj IPL,in
R3653 T13896 T13897 compound E2f1,KO
R3654 T13897 T13895 compound KO,IPL
R3655 T13898 T13899 punct (,shown
R3656 T13899 T13891 parataxis shown,seen
R3657 T13900 T13899 nsubj data,shown
R3658 T13901 T13899 neg not,shown
R3659 T13902 T13899 punct ),shown
R3660 T13903 T13891 punct .,seen
R3661 T13905 T13906 advmod However,was
R3662 T13907 T13906 punct ", ",was
R3663 T13908 T13909 advmod only,track
R3664 T13909 T13906 nsubj track,was
R3665 T13910 T13909 nummod one,track
R3666 T13911 T13909 nmod Calb2,track
R3667 T13912 T13911 punct +,Calb2
R3668 T13913 T13906 acomp evident,was
R3669 T13914 T13906 prep in,was
R3670 T13915 T13916 det the,IPL
R3672 T13917 T13918 compound Rb,KO
R3697 T13944 T13942 compound cell,bodies
R3698 T13945 T13940 prep in,quantified
R3699 T13946 T13947 det the,INL
R3700 T13947 T13945 pobj INL,in
R3701 T13948 T13949 compound Rb,KO
R3702 T13949 T13947 compound KO,INL
R3703 T13950 T13947 punct (,INL
R3704 T13951 T13947 acl corresponding,INL
R3705 T13952 T13951 prep to,corresponding
R3706 T13953 T13954 amod amacrine,cell
R3707 T13954 T13955 compound cell,staining
R3708 T13955 T13952 pobj staining,to
R3709 T13956 T13955 advmod only,staining
R3710 T13957 T13940 punct ),quantified
R3711 T13958 T13940 cc and,quantified
R3712 T13959 T13940 conj observed,quantified
R3713 T13960 T13961 det a,reduction
R3714 T13961 T13959 dobj reduction,observed
R3715 T13962 T13959 prep from,observed
R3716 T13963 T13962 pobj P8,from
R3717 T13964 T13963 advmod onwards,P8
R3718 T13965 T13966 punct (,3C
R3719 T13966 T13959 parataxis 3C,observed
R3720 T13967 T13966 compound Figures,3C
R3721 T13968 T13966 cc and,3C
R3722 T13969 T13966 conj S6,3C
R3723 T13970 T13966 punct ),3C
R3724 T13971 T13940 punct .,quantified
R3671 T13916 T13914 pobj IPL,in
R3673 T13918 T13916 compound KO,IPL
R3674 T13919 T13906 punct ", ",was
R3675 T13920 T13906 cc and,was
R3676 T13921 T13922 det this,defect
R3677 T13922 T13923 nsubjpass defect,rescued
R3678 T13923 T13906 conj rescued,was
R3679 T13924 T13923 auxpass was,rescued
R3680 T13925 T13923 neg not,rescued
R3681 T13926 T13923 prep in,rescued
R3682 T13927 T13928 det the,retina
R3683 T13928 T13926 pobj retina,in
R3684 T13929 T13930 compound Rb,E2f1
R3685 T13930 T13932 compound E2f1,DKO
R3686 T13931 T13930 punct /,E2f1
R3687 T13932 T13928 compound DKO,retina
R3688 T13933 T13934 punct (,3A
R3689 T13934 T13923 parataxis 3A,rescued
R3690 T13935 T13934 compound Figure,3A
R3691 T13936 T13934 punct ),3A
R3692 T13937 T13923 punct .,rescued
R3693 T13939 T13940 nsubj We,quantified
R3694 T13941 T13942 nmod Calb2,bodies
R3695 T13942 T13940 dobj bodies,quantified
R3696 T13943 T13941 punct +,Calb2

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T13557 40-52 CL:0000103 denotes bipolar cell
T13558 48-52 CL_GO_EXT:cell denotes cell
T13559 76-91 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T13560 109-114 CL_GO_EXT:cell denotes cells
T13561 162-164 PR_EXT:000013773 denotes Rb
T13562 165-169 PR_EXT:000006852 denotes E2f1
T13563 174-180 UBERON:0000966 denotes retina
T13564 189-196 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes markers
T13565 220-228 CHEBI_PR_EXT:protein denotes proteins
T13566 261-263 SO_EXT:wild_type_entity_or_quality denotes WT
T13567 265-269 PR_EXT:000006852 denotes E2f1
T13556 22-35 CL:0000210 denotes photoreceptor
T13568 278-280 PR_EXT:000013773 denotes Rb
T13569 281-285 PR_EXT:000006852 denotes E2f1
T13570 290-296 UBERON:0000966 denotes retina
T13571 322-329 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes markers
T13572 341-345 CL_GO_EXT:cell denotes cell
T13573 341-351 GO:0007049 denotes cell-cycle
T13574 357-366 GO:0006915 denotes apoptosis
T13575 379-394 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T13576 428-433 PR_EXT:000004968 denotes Calb2
T13577 435-445 PR_EXT:000004968 denotes calretinin
T13578 454-459 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes marks
T13579 472-480 _FRAGMENT denotes amacrine
T13580 494-498 CL:0000561 denotes cell
T13581 485-493 UBERON:0000045 denotes ganglion
T13582 485-498 CL:0000740 denotes ganglion cell
T13583 494-505 GO:0044297 denotes cell bodies
T13584 553-562 GO:0042995 denotes processes
T13585 594-599 PR_EXT:000004968 denotes Calb2
T13586 625-629 PR_EXT:000006852 denotes E2f1
T13587 673-678 PR_EXT:000004968 denotes Calb2
T13588 705-707 PR_EXT:000013773 denotes Rb
T13589 740-747 SO_EXT:sequence_rescue_process denotes rescued
T13590 755-757 PR_EXT:000013773 denotes Rb
T13591 758-762 PR_EXT:000006852 denotes E2f1
T13592 767-773 UBERON:0000966 denotes retina
T13593 801-806 PR_EXT:000004968 denotes Calb2
T13594 808-812 CL_GO_EXT:cell denotes cell
T13595 808-819 GO:0044297 denotes cell bodies
T13596 827-829 PR_EXT:000013773 denotes Rb
T13597 833-836 UBERON:0001791 denotes INL
T13598 855-868 CL:0000561 denotes amacrine cell
T13599 864-868 CL_GO_EXT:cell denotes cell
R3522 T13580 T13579 _lexicallyChainedTo cell,amacrine

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T13413 174-180 UBERON:0000966 denotes retina
T13414 265-269 PR:000006852 denotes E2f1
T13415 278-280 PR:000013773 denotes Rb
T13416 281-285 PR:000006852 denotes E2f1
T13417 290-296 UBERON:0000966 denotes retina
T13418 341-351 GO:0007049 denotes cell-cycle
T13419 357-366 GO:0006915 denotes apoptosis
T13420 428-433 PR:000004968 denotes Calb2
T13421 435-445 PR:000004968 denotes calretinin
T13422 472-480 _FRAGMENT denotes amacrine
T13423 494-498 CL:0000561 denotes cell
T13424 485-493 UBERON:0000045 denotes ganglion
T13425 485-498 CL:0000740 denotes ganglion cell
T13426 494-505 GO:0044297 denotes cell bodies
T13427 553-562 GO:0042995 denotes processes
T13428 594-599 PR:000004968 denotes Calb2
T13429 625-629 PR:000006852 denotes E2f1
T13430 673-678 PR:000004968 denotes Calb2
T13431 705-707 PR:000013773 denotes Rb
T13432 755-757 PR:000013773 denotes Rb
T13433 758-762 PR:000006852 denotes E2f1
T13434 767-773 UBERON:0000966 denotes retina
T13435 801-806 PR:000004968 denotes Calb2
T13436 808-819 GO:0044297 denotes cell bodies
T13437 827-829 PR:000013773 denotes Rb
T13438 833-836 UBERON:0001791 denotes INL
T13439 855-868 CL:0000561 denotes amacrine cell
T13409 22-35 CL:0000210 denotes photoreceptor
T13410 40-52 CL:0000103 denotes bipolar cell
T13411 162-164 PR:000013773 denotes Rb
T13412 165-169 PR:000006852 denotes E2f1
R3519 T13423 T13422 _lexicallyChainedTo cell,amacrine