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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1914394","sourcedb":"PMC","sourceid":"1914394","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1914394","text":", an important tumor suppressor, blocks division and death by inhibiting the E2f transcription factor family. In contrast, Rb is thought to promote differentiation by potentiating tissue-specific transcription factors, although differentiation defects in Rb null cells could be an indirect consequence of E2f-driven ","tracks":[]}