PMC:1914394 / 150-406 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1914394","sourcedb":"PMC","sourceid":"1914394","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1914394","text":"een known that loss of the retinoblastoma protein (Rb) perturbs neural differentiation, but the underlying mechanism has never been solved. Rb absence impairs cell cycle exit and triggers death of some neurons, so differentiation defects may well be indire","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T640","span":{"begin":4,"end":9},"obj":"VBN"},{"id":"T644","span":{"begin":10,"end":14},"obj":"IN"},{"id":"T645","span":{"begin":55,"end":63},"obj":"VBZ"},{"id":"T646","span":{"begin":15,"end":19},"obj":"NN"},{"id":"T647","span":{"begin":20,"end":22},"obj":"IN"},{"id":"T648","span":{"begin":23,"end":26},"obj":"DT"},{"id":"T649","span":{"begin":42,"end":49},"obj":"NN"},{"id":"T650","span":{"begin":27,"end":41},"obj":"NN"},{"id":"T651","span":{"begin":50,"end":51},"obj":"-LRB-"},{"id":"T652","span":{"begin":51,"end":53},"obj":"NN"},{"id":"T653","span":{"begin":53,"end":54},"obj":"-RRB-"},{"id":"T654","span":{"begin":64,"end":70},"obj":"JJ"},{"id":"T655","span":{"begin":71,"end":86},"obj":"NN"},{"id":"T656","span":{"begin":86,"end":88},"obj":","},{"id":"T657","span":{"begin":88,"end":91},"obj":"CC"},{"id":"T658","span":{"begin":92,"end":95},"obj":"DT"},{"id":"T659","span":{"begin":107,"end":116},"obj":"NN"},{"id":"T660","span":{"begin":96,"end":106},"obj":"JJ"},{"id":"T661","span":{"begin":132,"end":138},"obj":"VBN"},{"id":"T662","span":{"begin":117,"end":120},"obj":"VBZ"},{"id":"T663","span":{"begin":121,"end":126},"obj":"RB"},{"id":"T664","span":{"begin":127,"end":131},"obj":"VBN"},{"id":"T665","span":{"begin":138,"end":139},"obj":"."},{"id":"T667","span":{"begin":140,"end":142},"obj":"NN"},{"id":"T668","span":{"begin":143,"end":150},"obj":"NN"},{"id":"T669","span":{"begin":151,"end":158},"obj":"VBZ"},{"id":"T670","span":{"begin":247,"end":249},"obj":"VB"},{"id":"T671","span":{"begin":159,"end":163},"obj":"NN"},{"id":"T672","span":{"begin":164,"end":169},"obj":"NN"},{"id":"T673","span":{"begin":170,"end":174},"obj":"NN"},{"id":"T674","span":{"begin":175,"end":178},"obj":"CC"},{"id":"T675","span":{"begin":179,"end":187},"obj":"VBZ"},{"id":"T676","span":{"begin":188,"end":193},"obj":"NN"},{"id":"T677","span":{"begin":194,"end":196},"obj":"IN"},{"id":"T678","span":{"begin":197,"end":201},"obj":"DT"},{"id":"T679","span":{"begin":202,"end":209},"obj":"NNS"},{"id":"T680","span":{"begin":209,"end":211},"obj":","},{"id":"T681","span":{"begin":211,"end":213},"obj":"RB"},{"id":"T682","span":{"begin":214,"end":229},"obj":"NN"},{"id":"T683","span":{"begin":230,"end":237},"obj":"NNS"},{"id":"T684","span":{"begin":238,"end":241},"obj":"MD"},{"id":"T685","span":{"begin":242,"end":246},"obj":"RB"}],"relations":[{"id":"R24","pred":"mark","subj":"T644","obj":"T645"},{"id":"R25","pred":"ccomp","subj":"T645","obj":"T640"},{"id":"R26","pred":"nsubj","subj":"T646","obj":"T645"},{"id":"R27","pred":"prep","subj":"T647","obj":"T646"},{"id":"R28","pred":"det","subj":"T648","obj":"T649"},{"id":"R29","pred":"pobj","subj":"T649","obj":"T647"},{"id":"R30","pred":"compound","subj":"T650","obj":"T649"},{"id":"R31","pred":"punct","subj":"T651","obj":"T649"},{"id":"R32","pred":"appos","subj":"T652","obj":"T649"},{"id":"R33","pred":"punct","subj":"T653","obj":"T645"},{"id":"R34","pred":"amod","subj":"T654","obj":"T655"},{"id":"R35","pred":"dobj","subj":"T655","obj":"T645"},{"id":"R36","pred":"punct","subj":"T656","obj":"T640"},{"id":"R37","pred":"cc","subj":"T657","obj":"T640"},{"id":"R38","pred":"det","subj":"T658","obj":"T659"},{"id":"R39","pred":"nsubjpass","subj":"T659","obj":"T661"},{"id":"R40","pred":"amod","subj":"T660","obj":"T659"},{"id":"R41","pred":"conj","subj":"T661","obj":"T640"},{"id":"R42","pred":"aux","subj":"T662","obj":"T661"},{"id":"R43","pred":"neg","subj":"T663","obj":"T661"},{"id":"R44","pred":"auxpass","subj":"T664","obj":"T661"},{"id":"R45","pred":"punct","subj":"T665","obj":"T661"},{"id":"R46","pred":"compound","subj":"T667","obj":"T668"},{"id":"R47","pred":"nsubj","subj":"T668","obj":"T669"},{"id":"R48","pred":"ccomp","subj":"T669","obj":"T670"},{"id":"R49","pred":"compound","subj":"T671","obj":"T672"},{"id":"R50","pred":"compound","subj":"T672","obj":"T673"},{"id":"R51","pred":"dobj","subj":"T673","obj":"T669"},{"id":"R52","pred":"cc","subj":"T674","obj":"T669"},{"id":"R53","pred":"conj","subj":"T675","obj":"T669"},{"id":"R54","pred":"dobj","subj":"T676","obj":"T675"},{"id":"R55","pred":"prep","subj":"T677","obj":"T676"},{"id":"R56","pred":"det","subj":"T678","obj":"T679"},{"id":"R57","pred":"pobj","subj":"T679","obj":"T677"},{"id":"R58","pred":"punct","subj":"T680","obj":"T670"},{"id":"R59","pred":"advmod","subj":"T681","obj":"T670"},{"id":"R60","pred":"compound","subj":"T682","obj":"T683"},{"id":"R61","pred":"nsubj","subj":"T683","obj":"T670"},{"id":"R62","pred":"aux","subj":"T684","obj":"T670"},{"id":"R63","pred":"advmod","subj":"T685","obj":"T670"}],"attributes":[{"subj":"T640","pred":"source","obj":"craft-sa-dev"},{"subj":"T644","pred":"source","obj":"craft-sa-dev"},{"subj":"T645","pred":"source","obj":"craft-sa-dev"},{"subj":"T646","pred":"source","obj":"craft-sa-dev"},{"subj":"T647","pred":"source","obj":"craft-sa-dev"},{"subj":"T648","pred":"source","obj":"craft-sa-dev"},{"subj":"T649","pred":"source","obj":"craft-sa-dev"},{"subj":"T650","pred":"source","obj":"craft-sa-dev"},{"subj":"T651","pred":"source","obj":"craft-sa-dev"},{"subj":"T652","pred":"source","obj":"craft-sa-dev"},{"subj":"T653","pred":"source","obj":"craft-sa-dev"},{"subj":"T654","pred":"source","obj":"craft-sa-dev"},{"subj":"T655","pred":"source","obj":"craft-sa-dev"},{"subj":"T656","pred":"source","obj":"craft-sa-dev"},{"subj":"T657","pred":"source","obj":"craft-sa-dev"},{"subj":"T658","pred":"source","obj":"craft-sa-dev"},{"subj":"T659","pred":"source","obj":"craft-sa-dev"},{"subj":"T660","pred":"source","obj":"craft-sa-dev"},{"subj":"T661","pred":"source","obj":"craft-sa-dev"},{"subj":"T662","pred":"source","obj":"craft-sa-dev"},{"subj":"T663","pred":"source","obj":"craft-sa-dev"},{"subj":"T664","pred":"source","obj":"craft-sa-dev"},{"subj":"T665","pred":"source","obj":"craft-sa-dev"},{"subj":"T667","pred":"source","obj":"craft-sa-dev"},{"subj":"T668","pred":"source","obj":"craft-sa-dev"},{"subj":"T669","pred":"source","obj":"craft-sa-dev"},{"subj":"T670","pred":"source","obj":"craft-sa-dev"},{"subj":"T671","pred":"source","obj":"craft-sa-dev"},{"subj":"T672","pred":"source","obj":"craft-sa-dev"},{"subj":"T673","pred":"source","obj":"craft-sa-dev"},{"subj":"T674","pred":"source","obj":"craft-sa-dev"},{"subj":"T675","pred":"source","obj":"craft-sa-dev"},{"subj":"T676","pred":"source","obj":"craft-sa-dev"},{"subj":"T677","pred":"source","obj":"craft-sa-dev"},{"subj":"T678","pred":"source","obj":"craft-sa-dev"},{"subj":"T679","pred":"source","obj":"craft-sa-dev"},{"subj":"T680","pred":"source","obj":"craft-sa-dev"},{"subj":"T681","pred":"source","obj":"craft-sa-dev"},{"subj":"T682","pred":"source","obj":"craft-sa-dev"},{"subj":"T683","pred":"source","obj":"craft-sa-dev"},{"subj":"T684","pred":"source","obj":"craft-sa-dev"},{"subj":"T685","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T559","span":{"begin":27,"end":49},"obj":"PR_EXT:000013773"},{"id":"T560","span":{"begin":42,"end":49},"obj":"CHEBI_PR_EXT:protein"},{"id":"T561","span":{"begin":51,"end":53},"obj":"PR_EXT:000013773"},{"id":"T562","span":{"begin":64,"end":70},"obj":"UBERON_EXT:neural_tissue_or_nerve_or_nervous_system"},{"id":"T563","span":{"begin":71,"end":86},"obj":"GO_RO_EXT:developmental_differentiation_process"},{"id":"T564","span":{"begin":140,"end":142},"obj":"PR_EXT:000013773"},{"id":"T565","span":{"begin":159,"end":163},"obj":"CL_GO_EXT:cell"},{"id":"T566","span":{"begin":159,"end":169},"obj":"GO:0007049"},{"id":"T567","span":{"begin":188,"end":196},"obj":"_FRAGMENT"},{"id":"T568","span":{"begin":202,"end":209},"obj":"GO:0070997"},{"id":"T569","span":{"begin":202,"end":209},"obj":"CL:0000540"},{"id":"T570","span":{"begin":214,"end":229},"obj":"GO_RO_EXT:developmental_differentiation_process"}],"relations":[{"id":"R5","pred":"_lexicallyChainedTo","subj":"T568","obj":"T567"}],"attributes":[{"subj":"T559","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T560","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T561","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T562","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T563","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T564","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T565","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T566","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T567","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T568","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T569","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T570","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T515","span":{"begin":27,"end":49},"obj":"PR:000013773"},{"id":"T516","span":{"begin":51,"end":53},"obj":"PR:000013773"},{"id":"T517","span":{"begin":140,"end":142},"obj":"PR:000013773"},{"id":"T518","span":{"begin":159,"end":169},"obj":"GO:0007049"},{"id":"T519","span":{"begin":188,"end":196},"obj":"_FRAGMENT"},{"id":"T520","span":{"begin":202,"end":209},"obj":"GO:0070997"},{"id":"T521","span":{"begin":202,"end":209},"obj":"CL:0000540"}],"relations":[{"id":"R1","pred":"_lexicallyChainedTo","subj":"T520","obj":"T519"}],"attributes":[{"subj":"T515","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T516","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T517","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T518","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T519","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T520","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T521","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#ec93ac","default":true},{"id":"craft-ca-core-ex-dev","color":"#93c6ec"},{"id":"craft-ca-core-dev","color":"#e0ec93"}]}]}}