PMC:1892782 / 5481-5910 JSONTXT

{"project":"2_test","denotations":[{"id":"17540014-15665081-1690048","span":{"begin":199,"end":201},"obj":"15665081"},{"id":"17540014-15860779-1690049","span":{"begin":393,"end":395},"obj":"15860779"}],"text":"4) Structure conservation index (sci), which is defined as the ratio of the consensus folding energy and the average of the folding energies of the individual sequences, i.e. sci = consmfe/meanmfe, [15]. An sci close to 1 indicates perfect structure conservation, while alignments without structural conservation yield values close to 0. A more detailed discussion of the sci can be found in [16] in the context of RNA alignment."}