Id |
Subject |
Object |
Predicate |
Lexical cue |
T6543 |
289-295 |
NN |
denotes |
genome |
T6544 |
283-288 |
NN |
denotes |
mouse |
T6494 |
0-8 |
NN |
denotes |
Breeding |
T6495 |
9-20 |
NNS |
denotes |
experiments |
T6496 |
21-30 |
VBD |
denotes |
suggested |
T6497 |
31-35 |
IN |
denotes |
that |
T6498 |
62-71 |
VBN |
denotes |
inherited |
T6499 |
36-39 |
DT |
denotes |
the |
T6500 |
49-57 |
NN |
denotes |
disorder |
T6501 |
40-48 |
VBN |
denotes |
observed |
T6502 |
58-61 |
VBD |
denotes |
was |
T6503 |
72-74 |
IN |
denotes |
in |
T6504 |
75-77 |
DT |
denotes |
an |
T6505 |
98-104 |
NN |
denotes |
manner |
T6506 |
78-87 |
JJ |
denotes |
autosomal |
T6507 |
88-97 |
JJ |
denotes |
recessive |
T6508 |
104-105 |
. |
denotes |
. |
T6509 |
105-296 |
sentence |
denotes |
To map the location of the disease-causing lesion, we performed genome-wide linkage analysis using strain-specific single nucleotide polymorphisms (SNPs) at 120 loci across the mouse genome. |
T6510 |
106-108 |
TO |
denotes |
To |
T6511 |
109-112 |
VB |
denotes |
map |
T6512 |
160-169 |
VBD |
denotes |
performed |
T6513 |
113-116 |
DT |
denotes |
the |
T6514 |
117-125 |
NN |
denotes |
location |
T6515 |
126-128 |
IN |
denotes |
of |
T6516 |
129-132 |
DT |
denotes |
the |
T6517 |
149-155 |
NN |
denotes |
lesion |
T6518 |
133-140 |
NN |
denotes |
disease |
T6519 |
141-148 |
VBG |
denotes |
causing |
T6520 |
140-141 |
HYPH |
denotes |
- |
T6521 |
155-157 |
, |
denotes |
, |
T6522 |
157-159 |
PRP |
denotes |
we |
T6523 |
170-176 |
NN |
denotes |
genome |
T6524 |
177-181 |
JJ |
denotes |
wide |
T6525 |
176-177 |
HYPH |
denotes |
- |
T6526 |
190-198 |
NN |
denotes |
analysis |
T6527 |
182-189 |
NN |
denotes |
linkage |
T6528 |
199-204 |
VBG |
denotes |
using |
T6529 |
205-211 |
NN |
denotes |
strain |
T6530 |
212-220 |
JJ |
denotes |
specific |
T6531 |
211-212 |
HYPH |
denotes |
- |
T6532 |
239-252 |
NNS |
denotes |
polymorphisms |
T6533 |
221-227 |
JJ |
denotes |
single |
T6534 |
228-238 |
NN |
denotes |
nucleotide |
T6535 |
253-254 |
-LRB- |
denotes |
( |
T6536 |
254-258 |
NNS |
denotes |
SNPs |
T6537 |
258-259 |
-RRB- |
denotes |
) |
T6538 |
260-262 |
IN |
denotes |
at |
T6539 |
263-266 |
CD |
denotes |
120 |
T6540 |
267-271 |
NNS |
denotes |
loci |
T6541 |
272-278 |
IN |
denotes |
across |
T6542 |
279-282 |
DT |
denotes |
the |
T6545 |
295-296 |
. |
denotes |
. |
T6546 |
296-472 |
sentence |
denotes |
Analysis of these data showed a single genomic region with significant linkage to disease, providing a two-point LOD score of 5.13 at marker 20.MMHAP85FLG2 on Chromosome 6qE1. |
T6547 |
297-305 |
NN |
denotes |
Analysis |
T6548 |
320-326 |
VBD |
denotes |
showed |
T6549 |
306-308 |
IN |
denotes |
of |
T6550 |
309-314 |
DT |
denotes |
these |
T6551 |
315-319 |
NNS |
denotes |
data |
T6552 |
327-328 |
DT |
denotes |
a |
T6553 |
344-350 |
NN |
denotes |
region |
T6554 |
329-335 |
JJ |
denotes |
single |
T6555 |
336-343 |
JJ |
denotes |
genomic |
T6556 |
351-355 |
IN |
denotes |
with |
T6557 |
356-367 |
JJ |
denotes |
significant |
T6558 |
368-375 |
NN |
denotes |
linkage |
T6559 |
376-378 |
IN |
denotes |
to |
T6560 |
379-386 |
NN |
denotes |
disease |
T6561 |
386-388 |
, |
denotes |
, |
T6562 |
388-397 |
VBG |
denotes |
providing |
T6563 |
398-399 |
DT |
denotes |
a |
T6564 |
414-419 |
NN |
denotes |
score |
T6565 |
400-403 |
CD |
denotes |
two |
T6566 |
404-409 |
NN |
denotes |
point |
T6567 |
403-404 |
HYPH |
denotes |
- |
T6568 |
410-413 |
NN |
denotes |
LOD |
T6569 |
420-422 |
IN |
denotes |
of |
T6570 |
423-427 |
CD |
denotes |
5.13 |
T6571 |
428-430 |
IN |
denotes |
at |
T6572 |
431-437 |
NN |
denotes |
marker |
T6573 |
438-452 |
NN |
denotes |
20.MMHAP85FLG2 |
T6574 |
453-455 |
IN |
denotes |
on |
T6575 |
456-466 |
NN |
denotes |
Chromosome |
T6576 |
467-471 |
NN |
denotes |
6qE1 |
T6577 |
471-472 |
. |
denotes |
. |
T6578 |
472-570 |
sentence |
denotes |
The linked haplotype suggested the mutation had occurred on the 129x1/SvJ background (Figure S1). |
T6579 |
473-476 |
DT |
denotes |
The |
T6580 |
484-493 |
NN |
denotes |
haplotype |
T6581 |
477-483 |
VBN |
denotes |
linked |
T6582 |
494-503 |
VBD |
denotes |
suggested |
T6583 |
504-507 |
DT |
denotes |
the |
T6584 |
508-516 |
NN |
denotes |
mutation |
T6585 |
521-529 |
VBN |
denotes |
occurred |
T6586 |
517-520 |
VBD |
denotes |
had |
T6587 |
530-532 |
IN |
denotes |
on |
T6588 |
533-536 |
DT |
denotes |
the |
T6589 |
547-557 |
NN |
denotes |
background |
T6590 |
537-542 |
NN |
denotes |
129x1 |
T6591 |
543-546 |
NN |
denotes |
SvJ |
T6592 |
542-543 |
HYPH |
denotes |
/ |
T6593 |
558-559 |
-LRB- |
denotes |
( |
T6594 |
566-568 |
NN |
denotes |
S1 |
T6595 |
559-565 |
NN |
denotes |
Figure |
T6596 |
568-569 |
-RRB- |
denotes |
) |
T6597 |
569-570 |
. |
denotes |
. |
R476 |
T6494 |
T6495 |
compound |
Breeding,experiments |
R480 |
T6495 |
T6496 |
nsubj |
experiments,suggested |
R484 |
T6497 |
T6498 |
mark |
that,inherited |
R488 |
T6498 |
T6496 |
ccomp |
inherited,suggested |
R492 |
T6499 |
T6500 |
det |
the,disorder |
R494 |
T6500 |
T6498 |
nsubjpass |
disorder,inherited |
R498 |
T6501 |
T6500 |
amod |
observed,disorder |
R504 |
T6502 |
T6498 |
auxpass |
was,inherited |
R509 |
T6503 |
T6498 |
prep |
in,inherited |
R513 |
T6504 |
T6505 |
det |
an,manner |
R517 |
T6505 |
T6503 |
pobj |
manner,in |
R521 |
T6506 |
T6505 |
amod |
autosomal,manner |
R525 |
T6507 |
T6505 |
amod |
recessive,manner |
R529 |
T6508 |
T6496 |
punct |
.,suggested |
R532 |
T6510 |
T6511 |
aux |
To,map |
R538 |
T6511 |
T6512 |
advcl |
map,performed |
R541 |
T6513 |
T6514 |
det |
the,location |
R545 |
T6514 |
T6511 |
dobj |
location,map |
R546 |
T6515 |
T6514 |
prep |
of,location |
R547 |
T6516 |
T6517 |
det |
the,lesion |
R548 |
T6517 |
T6515 |
pobj |
lesion,of |
R549 |
T6518 |
T6519 |
npadvmod |
disease,causing |
R550 |
T6579 |
T6580 |
det |
The,haplotype |
R551 |
T6519 |
T6517 |
amod |
causing,lesion |
R552 |
T6580 |
T6582 |
nsubj |
haplotype,suggested |
R553 |
T6581 |
T6580 |
amod |
linked,haplotype |
R554 |
T6583 |
T6584 |
det |
the,mutation |
R555 |
T6584 |
T6585 |
nsubj |
mutation,occurred |
R556 |
T6520 |
T6519 |
punct |
-,causing |
R557 |
T6585 |
T6582 |
advcl |
occurred,suggested |
R558 |
T6586 |
T6585 |
aux |
had,occurred |
R559 |
T6521 |
T6512 |
punct |
", ",performed |
R560 |
T6587 |
T6585 |
prep |
on,occurred |
R561 |
T6588 |
T6589 |
det |
the,background |
R562 |
T6522 |
T6512 |
nsubj |
we,performed |
R563 |
T6589 |
T6587 |
pobj |
background,on |
R564 |
T6523 |
T6524 |
npadvmod |
genome,wide |
R565 |
T6590 |
T6591 |
compound |
129x1,SvJ |
R566 |
T6591 |
T6589 |
compound |
SvJ,background |
R567 |
T6524 |
T6526 |
amod |
wide,analysis |
R568 |
T6592 |
T6591 |
punct |
/,SvJ |
R569 |
T6593 |
T6594 |
punct |
(,S1 |
R570 |
T6594 |
T6582 |
parataxis |
S1,suggested |
R571 |
T6525 |
T6524 |
punct |
-,wide |
R572 |
T6595 |
T6594 |
compound |
Figure,S1 |
R573 |
T6596 |
T6594 |
punct |
),S1 |
R574 |
T6597 |
T6582 |
punct |
.,suggested |
R575 |
T6526 |
T6512 |
dobj |
analysis,performed |
R578 |
T6527 |
T6526 |
compound |
linkage,analysis |
R580 |
T6528 |
T6512 |
advcl |
using,performed |
R584 |
T6529 |
T6530 |
npadvmod |
strain,specific |
R588 |
T6530 |
T6532 |
amod |
specific,polymorphisms |
R591 |
T6531 |
T6530 |
punct |
-,specific |
R595 |
T6532 |
T6528 |
dobj |
polymorphisms,using |
R600 |
T6533 |
T6534 |
amod |
single,nucleotide |
R603 |
T6534 |
T6532 |
compound |
nucleotide,polymorphisms |
R608 |
T6535 |
T6532 |
punct |
(,polymorphisms |
R613 |
T6536 |
T6532 |
appos |
SNPs,polymorphisms |
R614 |
T6537 |
T6528 |
punct |
),using |
R619 |
T6538 |
T6528 |
prep |
at,using |
R621 |
T6539 |
T6540 |
nummod |
120,loci |
R625 |
T6540 |
T6538 |
pobj |
loci,at |
R630 |
T6541 |
T6528 |
prep |
across,using |
R633 |
T6542 |
T6543 |
det |
the,genome |
R637 |
T6543 |
T6541 |
pobj |
genome,across |
R641 |
T6544 |
T6543 |
compound |
mouse,genome |
R645 |
T6545 |
T6512 |
punct |
.,performed |
R649 |
T6547 |
T6548 |
nsubj |
Analysis,showed |
R654 |
T6549 |
T6547 |
prep |
of,Analysis |
R664 |
T6550 |
T6551 |
det |
these,data |
R668 |
T6551 |
T6549 |
pobj |
data,of |
R671 |
T6552 |
T6553 |
det |
a,region |
R673 |
T6553 |
T6548 |
dobj |
region,showed |
R675 |
T6554 |
T6553 |
amod |
single,region |
R678 |
T6555 |
T6553 |
amod |
genomic,region |
R682 |
T6556 |
T6553 |
prep |
with,region |
R684 |
T6557 |
T6558 |
amod |
significant,linkage |
R685 |
T6558 |
T6556 |
pobj |
linkage,with |
R687 |
T6559 |
T6558 |
prep |
to,linkage |
R690 |
T6560 |
T6559 |
pobj |
disease,to |
R693 |
T6561 |
T6548 |
punct |
", ",showed |
R696 |
T6562 |
T6548 |
advcl |
providing,showed |
R700 |
T6563 |
T6564 |
det |
a,score |
R704 |
T6564 |
T6562 |
dobj |
score,providing |
R708 |
T6565 |
T6566 |
nummod |
two,point |
R715 |
T6566 |
T6564 |
compound |
point,score |
R719 |
T6567 |
T6566 |
punct |
-,point |
R721 |
T6568 |
T6564 |
compound |
LOD,score |
R726 |
T6569 |
T6564 |
prep |
of,score |
R730 |
T6570 |
T6569 |
pobj |
5.13,of |
R733 |
T6571 |
T6564 |
prep |
at,score |
R736 |
T6572 |
T6573 |
compound |
marker,20.MMHAP85FLG2 |
R740 |
T6573 |
T6571 |
pobj |
20.MMHAP85FLG2,at |
R743 |
T6574 |
T6573 |
prep |
on,20.MMHAP85FLG2 |
R748 |
T6575 |
T6576 |
compound |
Chromosome,6qE1 |
R751 |
T6576 |
T6574 |
pobj |
6qE1,on |
R756 |
T6577 |
T6548 |
punct |
.,showed |