> top > docs > PMC:1892049 > spans > 2122-3079 > annotations

PMC:1892049 / 2122-3079 JSONTXT

Annnotations TAB JSON ListView MergeView

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1456 32-40 OBI_SO_EXT:gene_or_genetic_investigation_or_genetic_process denotes genetics
T1457 77-82 NCBITaxon:9606 denotes human
T1458 161-172 SO_EXT:sequence_alteration_process denotes mutagenesis
T1459 280-289 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T1460 314-319 NCBITaxon:10088 denotes mouse
T1461 320-328 GO_EXT:breeding denotes breeding
T1462 508-512 NCBITaxon:10088 denotes mice
T1463 531-539 GO_EXT:biological_movement_or_translocation_process denotes movement
T1464 585-601 SO_EXT:0001644 denotes targeting vector
T1465 671-678 SO_EXT:0000704 denotes genetic
T1466 702-710 GO_EXT:biological_movement_or_translocation_process denotes movement
T1467 772-780 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T1468 784-790 NCBITaxon:9606 denotes humans
T1469 842-850 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T1470 858-863 PR_EXT:000009158 denotes ITPR1
T1471 901-905 NCBITaxon:10088 denotes mice
T1472 913-928 UBERON:0014643 denotes spinocerebellar
T1473 950-956 NCBITaxon:9606 denotes humans

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1446 77-82 NCBITaxon:9606 denotes human
T1447 314-319 NCBITaxon:10088 denotes mouse
T1448 508-512 NCBITaxon:10088 denotes mice
T1449 585-601 SO:0001644 denotes targeting vector
T1450 671-678 SO:0000704 denotes genetic
T1451 784-790 NCBITaxon:9606 denotes humans
T1452 858-863 PR:000009158 denotes ITPR1
T1453 901-905 NCBITaxon:10088 denotes mice
T1454 913-928 UBERON:0014643 denotes spinocerebellar
T1455 950-956 NCBITaxon:9606 denotes humans

craft-sa-dev

Id Subject Object Predicate Lexical cue
T1474 13-16 DT denotes The
T1475 17-20 NN denotes use
T1476 95-101 VBN denotes become
T1477 21-23 IN denotes of
T1478 24-31 JJ denotes forward
T1479 32-40 NN denotes genetics
T1480 41-43 TO denotes to
T1481 44-50 VB denotes define
T1482 51-56 JJ denotes novel
T1483 57-61 NNS denotes loci
T1484 62-64 IN denotes of
T1485 65-73 NN denotes interest
T1486 74-76 IN denotes in
T1487 77-82 JJ denotes human
T1488 83-90 NN denotes disease
T1489 91-94 VBZ denotes has
T1490 102-114 RB denotes increasingly
T1491 115-121 JJ denotes viable
T1492 122-126 IN denotes with
T1493 127-130 DT denotes the
T1494 131-145 NN denotes implementation
T1495 146-148 IN denotes of
T1496 149-154 JJ denotes large
T1497 155-160 NN denotes scale
T1498 154-155 HYPH denotes -
T1499 173-181 NNS denotes programs
T1500 161-172 NN denotes mutagenesis
T1501 181-182 . denotes .
T1502 182-338 sentence denotes Prior to these initiatives this work was carried out in part by the investigation of spontaneous mutations that cause disorders in mouse breeding colonies.
T1503 183-188 RB denotes Prior
T1504 189-191 IN denotes to
T1505 224-231 VBN denotes carried
T1506 192-197 DT denotes these
T1507 198-209 NNS denotes initiatives
T1508 210-214 DT denotes this
T1509 215-219 NN denotes work
T1510 220-223 VBD denotes was
T1511 232-235 RP denotes out
T1512 236-238 IN denotes in
T1513 239-243 JJ denotes part
T1514 244-246 IN denotes by
T1515 247-250 DT denotes the
T1516 251-264 NN denotes investigation
T1517 265-267 IN denotes of
T1518 268-279 JJ denotes spontaneous
T1519 280-289 NNS denotes mutations
T1520 290-294 WDT denotes that
T1521 295-300 VBP denotes cause
T1522 301-310 NNS denotes disorders
T1523 311-313 IN denotes in
T1524 314-319 NN denotes mouse
T1525 329-337 NNS denotes colonies
T1526 320-328 NN denotes breeding
T1527 337-338 . denotes .
T1528 338-463 sentence denotes Careful observation of these serendipitous events has led to the establishment and study of many in vivo disease models [3].
T1529 339-346 JJ denotes Careful
T1530 347-358 NN denotes observation
T1531 393-396 VBN denotes led
T1532 359-361 IN denotes of
T1533 362-367 DT denotes these
T1534 382-388 NNS denotes events
T1535 368-381 JJ denotes serendipitous
T1536 389-392 VBZ denotes has
T1537 397-399 IN denotes to
T1538 400-403 DT denotes the
T1539 404-417 NN denotes establishment
T1540 418-421 CC denotes and
T1541 422-427 NN denotes study
T1542 428-430 IN denotes of
T1543 431-435 JJ denotes many
T1544 452-458 NNS denotes models
T1545 436-438 FW denotes in
T1546 439-443 FW denotes vivo
T1547 444-451 NN denotes disease
T1548 459-460 -LRB- denotes [
T1549 460-461 CD denotes 3
T1550 461-462 -RRB- denotes ]
T1551 462-463 . denotes .
T1552 463-615 sentence denotes During the generation of a knockout line of mice we noted an early movement disorder that was inherited independently of targeting vector transmission.
T1553 464-470 IN denotes During
T1554 516-521 VBD denotes noted
T1555 471-474 DT denotes the
T1556 475-485 NN denotes generation
T1557 486-488 IN denotes of
T1558 489-490 DT denotes a
T1559 500-504 NN denotes line
T1560 491-499 NN denotes knockout
T1561 505-507 IN denotes of
T1562 508-512 NNS denotes mice
T1563 513-515 PRP denotes we
T1564 522-524 DT denotes an
T1565 540-548 NN denotes disorder
T1566 525-530 JJ denotes early
T1567 531-539 NN denotes movement
T1568 549-553 WDT denotes that
T1569 558-567 VBN denotes inherited
T1570 554-557 VBD denotes was
T1571 568-581 RB denotes independently
T1572 582-584 IN denotes of
T1573 585-594 VBG denotes targeting
T1574 595-601 NN denotes vector
T1575 602-614 NN denotes transmission
T1576 614-615 . denotes .
T1577 615-791 sentence denotes We embarked on a series of experiments to identify the genetic lesion underlying this movement disorder and to identify a cognate disease and corresponding mutation in humans.
T1578 616-618 PRP denotes We
T1579 619-627 VBD denotes embarked
T1580 628-630 IN denotes on
T1581 631-632 DT denotes a
T1582 633-639 NN denotes series
T1583 640-642 IN denotes of
T1584 643-654 NNS denotes experiments
T1585 655-657 TO denotes to
T1586 658-666 VB denotes identify
T1587 667-670 DT denotes the
T1588 679-685 NN denotes lesion
T1589 671-678 JJ denotes genetic
T1590 686-696 VBG denotes underlying
T1591 697-701 DT denotes this
T1592 711-719 NN denotes disorder
T1593 702-710 NN denotes movement
T1594 720-723 CC denotes and
T1595 724-726 TO denotes to
T1596 727-735 VB denotes identify
T1597 736-737 DT denotes a
T1598 746-753 NN denotes disease
T1599 738-745 JJ denotes cognate
T1600 754-757 CC denotes and
T1601 758-771 VBG denotes corresponding
T1602 772-780 NN denotes mutation
T1603 781-783 IN denotes in
T1604 784-790 NNS denotes humans
T1605 790-791 . denotes .
T1606 791-957 sentence denotes Here we describe this effort and the discovery of deletion at the ITPR1 locus as a cause of this disorder in mice and of spinocerebellar ataxia 15 (SCA15) in humans.
T1607 792-796 RB denotes Here
T1608 800-808 VBP denotes describe
T1609 797-799 PRP denotes we
T1610 809-813 DT denotes this
T1611 814-820 NN denotes effort
T1612 821-824 CC denotes and
T1613 825-828 DT denotes the
T1614 829-838 NN denotes discovery
T1615 839-841 IN denotes of
T1616 842-850 NN denotes deletion
T1617 851-853 IN denotes at
T1618 854-857 DT denotes the
T1619 864-869 NN denotes locus
T1620 858-863 NN denotes ITPR1
T1621 870-872 IN denotes as
T1622 873-874 DT denotes a
T1623 875-880 NN denotes cause
T1624 881-883 IN denotes of
T1625 884-888 DT denotes this
T1626 889-897 NN denotes disorder
T1627 898-900 IN denotes in
T1628 901-905 NNS denotes mice
T1629 906-909 CC denotes and
T1630 910-912 IN denotes of
T1631 913-928 JJ denotes spinocerebellar
T1632 929-935 NN denotes ataxia
T1633 936-938 CD denotes 15
T1634 939-940 -LRB- denotes (
T1635 940-945 NN denotes SCA15
T1636 945-946 -RRB- denotes )
T1637 947-949 IN denotes in
T1638 950-956 NNS denotes humans
T1639 956-957 . denotes .
R242 T1474 T1475 det The,use
R243 T1475 T1476 nsubj use,become
R244 T1477 T1475 prep of,use
R245 T1478 T1479 amod forward,genetics
R246 T1479 T1477 pobj genetics,of
R247 T1480 T1481 aux to,define
R248 T1481 T1475 acl define,use
R249 T1482 T1483 amod novel,loci
R250 T1483 T1481 dobj loci,define
R251 T1484 T1483 prep of,loci
R252 T1485 T1484 pobj interest,of
R253 T1486 T1483 prep in,loci
R254 T1487 T1488 amod human,disease
R255 T1488 T1486 pobj disease,in
R256 T1489 T1476 aux has,become
R257 T1490 T1491 advmod increasingly,viable
R258 T1491 T1476 acomp viable,become
R259 T1492 T1476 prep with,become
R260 T1493 T1494 det the,implementation
R261 T1494 T1492 pobj implementation,with
R262 T1495 T1494 prep of,implementation
R263 T1496 T1497 amod large,scale
R264 T1497 T1499 compound scale,programs
R265 T1498 T1497 punct -,scale
R266 T1499 T1495 pobj programs,of
R267 T1500 T1499 compound mutagenesis,programs
R268 T1501 T1476 punct .,become
R269 T1503 T1504 advmod Prior,to
R270 T1504 T1505 prep to,carried
R271 T1506 T1507 det these,initiatives
R272 T1507 T1504 pobj initiatives,to
R273 T1508 T1509 det this,work
R274 T1509 T1505 nsubjpass work,carried
R275 T1510 T1505 auxpass was,carried
R276 T1511 T1505 prt out,carried
R277 T1512 T1505 prep in,carried
R278 T1513 T1512 amod part,in
R279 T1514 T1505 prep by,carried
R280 T1515 T1516 det the,investigation
R281 T1516 T1514 pobj investigation,by
R282 T1517 T1516 prep of,investigation
R283 T1518 T1519 amod spontaneous,mutations
R284 T1519 T1517 pobj mutations,of
R285 T1520 T1521 dep that,cause
R286 T1521 T1519 relcl cause,mutations
R287 T1522 T1521 dobj disorders,cause
R288 T1523 T1521 prep in,cause
R289 T1524 T1525 compound mouse,colonies
R290 T1525 T1523 pobj colonies,in
R291 T1526 T1525 compound breeding,colonies
R292 T1527 T1505 punct .,carried
R293 T1529 T1530 amod Careful,observation
R294 T1530 T1531 nsubj observation,led
R295 T1532 T1530 prep of,observation
R296 T1533 T1534 det these,events
R297 T1534 T1532 pobj events,of
R298 T1535 T1534 amod serendipitous,events
R299 T1536 T1531 aux has,led
R300 T1537 T1531 prep to,led
R301 T1538 T1539 det the,establishment
R302 T1539 T1537 pobj establishment,to
R303 T1540 T1539 cc and,establishment
R304 T1541 T1539 conj study,establishment
R305 T1542 T1539 prep of,establishment
R306 T1543 T1544 amod many,models
R307 T1544 T1542 pobj models,of
R308 T1545 T1546 advmod in,vivo
R309 T1546 T1544 amod vivo,models
R310 T1547 T1544 compound disease,models
R311 T1548 T1549 punct [,3
R312 T1549 T1531 parataxis 3,led
R313 T1550 T1549 punct ],3
R314 T1551 T1531 punct .,led
R315 T1553 T1554 prep During,noted
R316 T1555 T1556 det the,generation
R317 T1556 T1553 pobj generation,During
R318 T1557 T1556 prep of,generation
R319 T1558 T1559 det a,line
R320 T1559 T1557 pobj line,of
R321 T1560 T1559 compound knockout,line
R322 T1561 T1559 prep of,line
R323 T1562 T1561 pobj mice,of
R324 T1563 T1554 nsubj we,noted
R325 T1564 T1565 det an,disorder
R326 T1565 T1554 dobj disorder,noted
R327 T1566 T1565 amod early,disorder
R328 T1567 T1565 compound movement,disorder
R329 T1568 T1569 dep that,inherited
R330 T1569 T1565 relcl inherited,disorder
R331 T1570 T1569 auxpass was,inherited
R332 T1571 T1569 advmod independently,inherited
R333 T1572 T1571 prep of,independently
R334 T1573 T1574 amod targeting,vector
R335 T1574 T1575 compound vector,transmission
R336 T1575 T1572 pobj transmission,of
R337 T1576 T1554 punct .,noted
R338 T1578 T1579 nsubj We,embarked
R339 T1580 T1579 prep on,embarked
R340 T1581 T1582 det a,series
R341 T1582 T1580 pobj series,on
R342 T1583 T1582 prep of,series
R343 T1584 T1583 pobj experiments,of
R344 T1585 T1586 aux to,identify
R345 T1586 T1579 advcl identify,embarked
R346 T1587 T1588 det the,lesion
R347 T1588 T1586 dobj lesion,identify
R348 T1589 T1588 amod genetic,lesion
R349 T1590 T1588 acl underlying,lesion
R350 T1591 T1592 det this,disorder
R351 T1592 T1590 dobj disorder,underlying
R352 T1593 T1592 compound movement,disorder
R353 T1594 T1586 cc and,identify
R354 T1595 T1596 aux to,identify
R355 T1596 T1586 conj identify,identify
R356 T1597 T1598 det a,disease
R357 T1598 T1596 dobj disease,identify
R358 T1599 T1598 amod cognate,disease
R359 T1600 T1598 cc and,disease
R360 T1601 T1602 amod corresponding,mutation
R361 T1602 T1598 conj mutation,disease
R362 T1603 T1596 prep in,identify
R363 T1604 T1603 pobj humans,in
R364 T1605 T1579 punct .,embarked
R365 T1607 T1608 advmod Here,describe
R366 T1609 T1608 nsubj we,describe
R367 T1610 T1611 det this,effort
R368 T1611 T1608 dobj effort,describe
R369 T1612 T1611 cc and,effort
R370 T1613 T1614 det the,discovery
R371 T1614 T1611 conj discovery,effort
R372 T1615 T1614 prep of,discovery
R373 T1616 T1615 pobj deletion,of
R374 T1617 T1616 prep at,deletion
R375 T1618 T1619 det the,locus
R376 T1619 T1617 pobj locus,at
R377 T1620 T1619 compound ITPR1,locus
R378 T1621 T1608 prep as,describe
R379 T1622 T1623 det a,cause
R380 T1623 T1621 pobj cause,as
R381 T1624 T1623 prep of,cause
R382 T1625 T1626 det this,disorder
R383 T1626 T1624 pobj disorder,of
R384 T1627 T1626 prep in,disorder
R385 T1628 T1627 pobj mice,in
R386 T1629 T1624 cc and,of
R387 T1630 T1624 conj of,of
R388 T1631 T1632 amod spinocerebellar,ataxia
R389 T1632 T1630 pobj ataxia,of
R390 T1633 T1632 nummod 15,ataxia
R391 T1634 T1632 punct (,ataxia
R392 T1635 T1632 appos SCA15,ataxia
R393 T1636 T1632 punct ),ataxia
R394 T1637 T1632 prep in,ataxia
R395 T1638 T1637 pobj humans,in
R396 T1639 T1608 punct .,describe

2_test

Id Subject Object Predicate Lexical cue
17590087-16179741-85657842 460-461 16179741 denotes 3
T23894 460-461 16179741 denotes 3