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PMC:1892049 / 15829-16631 JSONTXT

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craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6278 578-583 PR_EXT:000009158 denotes Itpr1
T6279 599-606 SO_EXT:0000417 denotes domains
T6280 611-621 CHEBI_SO_EXT:N_terminus_or_N_terminal_region denotes N-terminal
T6281 622-643 CHEBI:25450 denotes inositol triphosphate
T6282 644-651 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T6283 644-658 SO_EXT:0100018 denotes binding domain
T6284 671-677 SO_EXT:0000417 denotes domain
T6285 685-695 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T6286 701-709 GO:0016020 denotes membrane
T6287 739-746 CHEBI_PR_EXT:protein denotes protein
T6288 739-755 GO_EXT:0004691 denotes protein kinase A
T6289 756-771 GO_PATO_EXT:phosphorylation_process denotes phosphorylation
T6290 785-788 CHEBI_EXT:ATP denotes ATP
T6291 789-796 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T6292 789-801 SO_EXT:0000409 denotes binding site
T16231 36-41 PR_EXT:000009158 denotes ITPR1
T16232 42-49 CHEBI_PR_EXT:protein denotes Protein
T16233 60-63 NCBITaxon:10376 denotes EBV
T16234 149-154 PR_EXT:000009158 denotes ITPR1
T16235 165-168 NCBITaxon:10376 denotes EBV
T16236 182-193 CL:0000542 denotes lymphocytes
T16237 241-246 PR_EXT:000009158 denotes ITPR1
T16238 247-255 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T16239 336-344 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T16240 385-390 PR_EXT:000009158 denotes ITPR1
T16241 391-399 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T16242 428-433 PR_EXT:000009158 denotes ITPR1
T16243 555-563 GO:0042571 denotes antibody
T16244 572-576 PR_EXT:000003676 denotes ACTB

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T5964 578-583 PR:000009158 denotes Itpr1
T5965 599-606 SO:0000417 denotes domains
T5966 622-643 CHEBI:25450 denotes inositol triphosphate
T5967 644-658 SO:0100018 denotes binding domain
T5968 671-677 SO:0000417 denotes domain
T5969 701-709 GO:0016020 denotes membrane
T5970 789-801 SO:0000409 denotes binding site
T16221 36-41 PR:000009158 denotes ITPR1
T16222 60-63 NCBITaxon:10376 denotes EBV
T16223 149-154 PR:000009158 denotes ITPR1
T16224 165-168 NCBITaxon:10376 denotes EBV
T16225 182-193 CL:0000542 denotes lymphocytes
T16226 241-246 PR:000009158 denotes ITPR1
T16227 385-390 PR:000009158 denotes ITPR1
T16228 428-433 PR:000009158 denotes ITPR1
T16229 555-563 GO:0042571 denotes antibody
T16230 572-576 PR:000003676 denotes ACTB

craft-sa-dev

Id Subject Object Predicate Lexical cue
T8122 0-802 sentence denotes Figure 4 Western Blot Analysis of ITPR1 Protein Levels in EBV Immortalized Lymphoblasts from AUS1 Family Members Western blot performed to examine ITPR1 levels in EBV immortalized lymphocytes from AUS1 affected family members carrying the ITPR1 deletion and from an AUS1 family member of unknown disease status who does not carry the deletion. Notably the samples from patients with ITPR1 deletion show a dramatic decrease in ITPR1 levels. To demonstrate equal loading, these samples were diluted one in five, and the Western blot was repeated using an antibody against ACTB. Itpr1 contains three domains, an N-terminal inositol triphosphate binding domain, a coupling domain, and a C-terminal transmembrane domain; it also contains two protein kinase A phosphorylation sites and an ATP-binding site.
T8123 578-583 NN denotes Itpr1
T8124 584-592 VBZ denotes contains
T8125 726-734 VBZ denotes contains
T8126 593-598 CD denotes three
T8127 599-606 NNS denotes domains
T8128 606-608 , denotes ,
T8129 608-610 DT denotes an
T8130 652-658 NN denotes domain
T8131 611-612 NN denotes N
T8132 613-621 JJ denotes terminal
T8133 612-613 HYPH denotes -
T8134 622-630 NN denotes inositol
T8135 631-643 NN denotes triphosphate
T8136 644-651 NN denotes binding
T8137 658-660 , denotes ,
T8138 660-661 DT denotes a
T8139 671-677 NN denotes domain
T8140 662-670 VBG denotes coupling
T8141 677-679 , denotes ,
T8142 679-682 CC denotes and
T8143 683-684 DT denotes a
T8144 710-716 NN denotes domain
T8145 685-686 NN denotes C
T8146 687-695 JJ denotes terminal
T8147 686-687 HYPH denotes -
T8148 696-709 NN denotes transmembrane
T8149 716-717 : denotes ;
T8150 718-720 PRP denotes it
T8151 721-725 RB denotes also
T8152 735-738 CD denotes two
T8153 772-777 NNS denotes sites
T8154 739-746 NN denotes protein
T8155 754-755 NN denotes A
T8156 747-753 NN denotes kinase
T8157 756-771 NN denotes phosphorylation
T8158 778-781 CC denotes and
T8159 782-784 DT denotes an
T8160 797-801 NN denotes site
T8161 785-788 NN denotes ATP
T8162 789-796 VBG denotes binding
T8163 788-789 HYPH denotes -
T8164 801-802 . denotes .
T16337 555-563 NN denotes antibody
T16338 564-571 IN denotes against
T16245 11-18 NNP denotes Western
T16246 19-23 NN denotes Blot
T16247 24-32 NN denotes Analysis
T16248 33-35 IN denotes of
T16249 36-41 NN denotes ITPR1
T16250 50-56 NNS denotes Levels
T16251 42-49 NN denotes Protein
T16252 57-59 IN denotes in
T16253 60-63 NN denotes EBV
T16254 77-89 NNS denotes Lymphoblasts
T16255 64-76 VBN denotes Immortalized
T16256 90-94 IN denotes from
T16257 95-99 NN denotes AUS1
T16258 107-114 NNS denotes Members
T16259 100-106 NN denotes Family
T16260 114-345 sentence denotes Western blot performed to examine ITPR1 levels in EBV immortalized lymphocytes from AUS1 affected family members carrying the ITPR1 deletion and from an AUS1 family member of unknown disease status who does not carry the deletion.
T16261 115-122 NNP denotes Western
T16262 123-127 NN denotes blot
T16263 128-137 VBN denotes performed
T16264 138-140 TO denotes to
T16265 141-148 VB denotes examine
T16266 149-154 NN denotes ITPR1
T16267 155-161 NNS denotes levels
T16268 162-164 IN denotes in
T16269 165-168 NN denotes EBV
T16270 182-193 NNS denotes lymphocytes
T16271 169-181 VBN denotes immortalized
T16272 194-198 IN denotes from
T16273 199-203 NN denotes AUS1
T16274 204-212 VBN denotes affected
T16275 220-227 NNS denotes members
T16276 213-219 NN denotes family
T16277 228-236 VBG denotes carrying
T16278 237-240 DT denotes the
T16279 247-255 NN denotes deletion
T16280 241-246 NN denotes ITPR1
T16281 256-259 CC denotes and
T16282 260-264 IN denotes from
T16283 265-267 DT denotes an
T16284 280-286 NN denotes member
T16285 268-272 NN denotes AUS1
T16286 273-279 NN denotes family
T16287 287-289 IN denotes of
T16288 290-297 JJ denotes unknown
T16289 306-312 NN denotes status
T16290 298-305 NN denotes disease
T16291 313-316 WP denotes who
T16292 326-331 VB denotes carry
T16293 317-321 VBZ denotes does
T16294 322-325 RB denotes not
T16295 332-335 DT denotes the
T16296 336-344 NN denotes deletion
T16297 344-345 . denotes .
T16298 345-441 sentence denotes Notably the samples from patients with ITPR1 deletion show a dramatic decrease in ITPR1 levels.
T16299 346-353 RB denotes Notably
T16300 400-404 VBP denotes show
T16301 354-357 DT denotes the
T16302 358-365 NNS denotes samples
T16303 366-370 IN denotes from
T16304 371-379 NNS denotes patients
T16305 380-384 IN denotes with
T16306 385-390 NN denotes ITPR1
T16307 391-399 NN denotes deletion
T16308 405-406 DT denotes a
T16309 416-424 NN denotes decrease
T16310 407-415 JJ denotes dramatic
T16311 425-427 IN denotes in
T16312 428-433 NN denotes ITPR1
T16313 434-440 NNS denotes levels
T16314 440-441 . denotes .
T16315 441-577 sentence denotes To demonstrate equal loading, these samples were diluted one in five, and the Western blot was repeated using an antibody against ACTB.
T16316 442-444 TO denotes To
T16317 445-456 VB denotes demonstrate
T16318 491-498 VBN denotes diluted
T16319 457-462 JJ denotes equal
T16320 463-470 NN denotes loading
T16321 470-472 , denotes ,
T16322 472-477 DT denotes these
T16323 478-485 NNS denotes samples
T16324 486-490 VBD denotes were
T16325 499-502 CD denotes one
T16326 503-505 IN denotes in
T16327 506-510 CD denotes five
T16328 510-512 , denotes ,
T16329 512-515 CC denotes and
T16330 516-519 DT denotes the
T16331 528-532 NN denotes blot
T16332 520-527 NNP denotes Western
T16333 537-545 VBN denotes repeated
T16334 533-536 VBD denotes was
T16335 546-551 VBG denotes using
T16336 552-554 DT denotes an
T16339 572-576 NN denotes ACTB
T16340 576-577 . denotes .
R2029 T8123 T8124 nsubj Itpr1,contains
R2030 T8124 T8125 ccomp contains,contains
R2032 T8126 T8127 nummod three,domains
R2033 T8127 T8124 dobj domains,contains
R2035 T8128 T8127 punct ", ",domains
R2037 T8129 T8130 det an,domain
R2039 T8130 T8127 appos domain,domains
R2040 T8131 T8132 npadvmod N,terminal
R2041 T8132 T8130 amod terminal,domain
R2043 T8133 T8132 punct -,terminal
R2044 T8134 T8130 compound inositol,domain
R2045 T8135 T8130 compound triphosphate,domain
R2047 T8136 T8130 compound binding,domain
R2048 T8137 T8130 punct ", ",domain
R2050 T8138 T8139 det a,domain
R2051 T8139 T8130 conj domain,domain
R2052 T8140 T8139 amod coupling,domain
R2054 T8141 T8139 punct ", ",domain
R2055 T8142 T8139 cc and,domain
R2057 T8143 T8144 det a,domain
R2058 T8144 T8139 conj domain,domain
R2059 T8145 T8146 npadvmod C,terminal
R2061 T8146 T8144 amod terminal,domain
R2062 T8147 T8146 punct -,terminal
R2063 T8148 T8144 compound transmembrane,domain
R2064 T8149 T8125 punct ;,contains
R2065 T8150 T8125 nsubj it,contains
R2067 T8151 T8125 advmod also,contains
R2068 T8152 T8153 nummod two,sites
R2069 T8153 T8125 dobj sites,contains
R2071 T8154 T8155 compound protein,A
R2072 T8155 T8153 compound A,sites
R2073 T8156 T8155 compound kinase,A
R2075 T8157 T8153 compound phosphorylation,sites
R2076 T8158 T8153 cc and,sites
R2077 T8159 T8160 det an,site
R2079 T8160 T8153 conj site,sites
R2080 T8161 T8162 npadvmod ATP,binding
R2081 T8162 T8160 amod binding,site
R2083 T8163 T8162 punct -,binding
R2084 T8164 T8125 punct .,contains
R4848 T16245 T16246 compound Western,Blot
R4849 T16246 T16247 compound Blot,Analysis
R4850 T16248 T16247 prep of,Analysis
R4851 T16249 T16250 compound ITPR1,Levels
R4852 T16250 T16248 pobj Levels,of
R4853 T16251 T16250 compound Protein,Levels
R4854 T16252 T16247 prep in,Analysis
R4855 T16253 T16254 nmod EBV,Lymphoblasts
R4856 T16254 T16252 pobj Lymphoblasts,in
R4857 T16255 T16254 amod Immortalized,Lymphoblasts
R4858 T16256 T16254 prep from,Lymphoblasts
R4859 T16257 T16258 compound AUS1,Members
R4860 T16258 T16256 pobj Members,from
R4861 T16259 T16258 compound Family,Members
R4862 T16261 T16262 compound Western,blot
R4863 T16263 T16262 acl performed,blot
R4864 T16264 T16265 aux to,examine
R4865 T16265 T16263 advcl examine,performed
R4866 T16266 T16267 compound ITPR1,levels
R4867 T16267 T16265 dobj levels,examine
R4868 T16268 T16267 prep in,levels
R4869 T16269 T16270 nmod EBV,lymphocytes
R4870 T16270 T16268 pobj lymphocytes,in
R4871 T16271 T16270 amod immortalized,lymphocytes
R4872 T16272 T16270 prep from,lymphocytes
R4873 T16273 T16274 npadvmod AUS1,affected
R4874 T16274 T16275 amod affected,members
R4875 T16275 T16272 pobj members,from
R4876 T16276 T16275 compound family,members
R4877 T16277 T16275 acl carrying,members
R4878 T16278 T16279 det the,deletion
R4879 T16279 T16277 dobj deletion,carrying
R4880 T16280 T16279 compound ITPR1,deletion
R4881 T16281 T16272 cc and,from
R4882 T16282 T16272 conj from,from
R4883 T16283 T16284 det an,member
R4884 T16284 T16282 pobj member,from
R4885 T16285 T16284 compound AUS1,member
R4886 T16286 T16284 compound family,member
R4887 T16287 T16284 prep of,member
R4888 T16288 T16289 amod unknown,status
R4889 T16289 T16287 pobj status,of
R4890 T16290 T16289 compound disease,status
R4891 T16291 T16292 dep who,carry
R4892 T16292 T16284 relcl carry,member
R4893 T16293 T16292 aux does,carry
R4894 T16294 T16292 neg not,carry
R4895 T16295 T16296 det the,deletion
R4896 T16296 T16292 dobj deletion,carry
R4897 T16297 T16262 punct .,blot
R4898 T16299 T16300 advmod Notably,show
R4899 T16301 T16302 det the,samples
R4900 T16302 T16300 nsubj samples,show
R4901 T16303 T16302 prep from,samples
R4902 T16304 T16303 pobj patients,from
R4903 T16305 T16304 prep with,patients
R4904 T16306 T16307 compound ITPR1,deletion
R4905 T16307 T16305 pobj deletion,with
R4906 T16308 T16309 det a,decrease
R4907 T16309 T16300 dobj decrease,show
R4908 T16310 T16309 amod dramatic,decrease
R4909 T16311 T16309 prep in,decrease
R4910 T16312 T16313 compound ITPR1,levels
R4911 T16313 T16311 pobj levels,in
R4912 T16314 T16300 punct .,show
R4913 T16316 T16317 aux To,demonstrate
R4914 T16317 T16318 advcl demonstrate,diluted
R4915 T16319 T16320 amod equal,loading
R4916 T16320 T16317 dobj loading,demonstrate
R4917 T16321 T16318 punct ", ",diluted
R4918 T16322 T16323 det these,samples
R4919 T16323 T16318 nsubjpass samples,diluted
R4920 T16324 T16318 auxpass were,diluted
R4921 T16325 T16318 npadvmod one,diluted
R4922 T16326 T16325 prep in,one
R4923 T16327 T16326 pobj five,in
R4924 T16328 T16318 punct ", ",diluted
R4925 T16329 T16318 cc and,diluted
R4926 T16330 T16331 det the,blot
R4927 T16331 T16333 nsubjpass blot,repeated
R4928 T16332 T16331 compound Western,blot
R4929 T16333 T16318 conj repeated,diluted
R4930 T16334 T16333 auxpass was,repeated
R4931 T16335 T16333 advcl using,repeated
R4932 T16336 T16337 det an,antibody
R4933 T16337 T16335 dobj antibody,using
R4934 T16338 T16337 prep against,antibody
R4935 T16339 T16338 pobj ACTB,against
R4936 T16340 T16318 punct .,diluted