PMC:1867812 / 6094-6703 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1867812","sourcedb":"PMC","sourceid":"1867812","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1867812","text":"• Propose a contact map-based approach to analyze protein folding trajectories: Our previous work focused on identifying structural signatures in native conformation of proteins in different classes or folds. Thus, there is no temporal component involved. In contrast, a folding trajectory has both spatial and temporal components. In addition, bit-patterns in a folding trajectory will interact with each other and evolve over time. Moreover, the proposed approach also effectively integrates 3D structural information in the overall analysis. This is critical in understanding the protein folding mechanism.","tracks":[]}