PMC:1867812 / 42729-43770 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1867812","sourcedb":"PMC","sourceid":"1867812","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1867812","text":"Protein PDB Identifier: BBA5; Primary sequence: 23 residues; Designed protein;Native fold: N-terminal 1–10 β hairpin, C-terminal 11–23 α-helix\nTrajectory Two trajectories: T23 and T24;T23: 192 conformations; T24: 150 conformations\nContact map Based on contacts between α-carbons.Two α-carbons are in contact if their Euclidian distance is ≤ 8.5 Å\nBit-patterns A total of 352 unique maximally connected bit-patterns were identified from all conformations;Average number of bit-patterns per conformation is 6;Bit-patterns are further classified into 10 approximately equivalent types\nInteracting bit-patterns If at least one pair of α-carbons, one from each bit-pattern, is of Euclidian distance ≤ 10 Å\nFrequent SOAPs A SOAP is frequent if it appears in ≥ 5 conformations;A total of 444 frequent SOAPs identified in trajectory T23, and 258 in T24\nConsensus partial folding pathway We identified a consensus partial folding pathway across the two trajectories.It is composed of 71 pairs of similar conformations, one from each trajectory","divisions":[{"label":"tr","span":{"begin":0,"end":143}},{"label":"td","span":{"begin":0,"end":7}},{"label":"td","span":{"begin":9,"end":143}},{"label":"tr","span":{"begin":144,"end":232}},{"label":"td","span":{"begin":144,"end":154}},{"label":"td","span":{"begin":156,"end":232}},{"label":"tr","span":{"begin":233,"end":349}},{"label":"td","span":{"begin":233,"end":244}},{"label":"td","span":{"begin":246,"end":349}},{"label":"tr","span":{"begin":350,"end":585}},{"label":"td","span":{"begin":350,"end":362}},{"label":"td","span":{"begin":364,"end":585}},{"label":"tr","span":{"begin":586,"end":705}},{"label":"td","span":{"begin":586,"end":610}},{"label":"td","span":{"begin":612,"end":705}},{"label":"tr","span":{"begin":706,"end":850}},{"label":"td","span":{"begin":706,"end":720}},{"label":"td","span":{"begin":722,"end":850}},{"label":"td","span":{"begin":851,"end":884}}],"tracks":[]}