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old FVB/N and DBA/1J mice were used for the detection of gene expression. They were divided into four experimental groups according to the different phases of CIA, namely naive control (NC), post-immunisation (PI), onset of arthritis (OA) and chronic arthritis (CA) (Table 1). The NC group contained non-immunised mice that were sacrificed at the age of 8 weeks. The mice in the PI group were sacrificed on day 10 after immunisation. The mice in the OA group were sacrificed on day 35 after immunisation. Three FVB/N non-arthritic mice and three DBA/1 mice that showed signs of arthritis on day 33 or 34 after immunisation were sacrificed on day 35 after immunisation. The mice in the CA group were sacrificed on day 95 after immunisation. Three non-arthritic FVB/N mice and three DBA/1 mice that had developed arthritis for at least two months were sacrificed on day 95 after immunisation."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T4027","span":{"begin":32,"end":36},"obj":"NCBITaxon:10088"},{"id":"T4028","span":{"begin":68,"end":72},"obj":"SO_EXT:0000704"},{"id":"T4029","span":{"begin":68,"end":83},"obj":"GO:0010467"},{"id":"T4030","span":{"begin":325,"end":329},"obj":"NCBITaxon:10088"},{"id":"T4031","span":{"begin":340,"end":350},"obj":"GO_EXT:killing"},{"id":"T4032","span":{"begin":378,"end":382},"obj":"NCBITaxon:10088"},{"id":"T4033","span":{"begin":404,"end":414},"obj":"GO_EXT:killing"},{"id":"T4034","span":{"begin":449,"end":453},"obj":"NCBITaxon:10088"},{"id":"T4035","span":{"begin":475,"end":485},"obj":"GO_EXT:killing"},{"id":"T4036","span":{"begin":542,"end":546},"obj":"NCBITaxon:10088"},{"id":"T4037","span":{"begin":563,"end":567},"obj":"NCBITaxon:10088"},{"id":"T4038","span":{"begin":639,"end":649},"obj":"GO_EXT:killing"},{"id":"T4039","span":{"begin":684,"end":688},"obj":"NCBITaxon:10088"},{"id":"T4040","span":{"begin":710,"end":720},"obj":"GO_EXT:killing"},{"id":"T4041","span":{"begin":777,"end":781},"obj":"NCBITaxon:10088"},{"id":"T4042","span":{"begin":798,"end":802},"obj":"NCBITaxon:10088"},{"id":"T4043","span":{"begin":861,"end":871},"obj":"GO_EXT:killing"}],"text":"Eight-week old FVB/N and DBA/1J mice were used for the detection of gene expression. They were divided into four experimental groups according to the different phases of CIA, namely naive control (NC), post-immunisation (PI), onset of arthritis (OA) and chronic arthritis (CA) (Table 1). The NC group contained non-immunised mice that were sacrificed at the age of 8 weeks. The mice in the PI group were sacrificed on day 10 after immunisation. The mice in the OA group were sacrificed on day 35 after immunisation. Three FVB/N non-arthritic mice and three DBA/1 mice that showed signs of arthritis on day 33 or 34 after immunisation were sacrificed on day 35 after immunisation. The mice in the CA group were sacrificed on day 95 after immunisation. Three non-arthritic FVB/N mice and three DBA/1 mice that had developed arthritis for at least two months were sacrificed on day 95 after immunisation."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T4003","span":{"begin":32,"end":36},"obj":"NCBITaxon:10088"},{"id":"T4004","span":{"begin":68,"end":72},"obj":"SO:0000704"},{"id":"T4005","span":{"begin":68,"end":83},"obj":"GO:0010467"},{"id":"T4006","span":{"begin":325,"end":329},"obj":"NCBITaxon:10088"},{"id":"T4007","span":{"begin":378,"end":382},"obj":"NCBITaxon:10088"},{"id":"T4008","span":{"begin":449,"end":453},"obj":"NCBITaxon:10088"},{"id":"T4009","span":{"begin":542,"end":546},"obj":"NCBITaxon:10088"},{"id":"T4010","span":{"begin":563,"end":567},"obj":"NCBITaxon:10088"},{"id":"T4011","span":{"begin":684,"end":688},"obj":"NCBITaxon:10088"},{"id":"T4012","span":{"begin":777,"end":781},"obj":"NCBITaxon:10088"},{"id":"T4013","span":{"begin":798,"end":802},"obj":"NCBITaxon:10088"}],"text":"Eight-week old FVB/N and DBA/1J mice were used for the detection of gene expression. They were divided into four experimental groups according to the different phases of CIA, namely naive control (NC), post-immunisation (PI), onset of arthritis (OA) and chronic arthritis (CA) (Table 1). The NC group contained non-immunised mice that were sacrificed at the age of 8 weeks. The mice in the PI group were sacrificed on day 10 after immunisation. The mice in the OA group were sacrificed on day 35 after immunisation. Three FVB/N non-arthritic mice and three DBA/1 mice that showed signs of arthritis on day 33 or 34 after immunisation were sacrificed on day 35 after immunisation. The mice in the CA group were sacrificed on day 95 after immunisation. Three non-arthritic FVB/N mice and three DBA/1 mice that had developed arthritis for at least two months were sacrificed on day 95 after immunisation."}