Id |
Subject |
Object |
Predicate |
Lexical cue |
T1016 |
0-4 |
DT |
denotes |
Each |
T1017 |
5-13 |
NN |
denotes |
mutation |
T1018 |
107-115 |
VBD |
denotes |
resulted |
T1019 |
14-21 |
VBD |
denotes |
deleted |
T1020 |
22-23 |
SYM |
denotes |
> |
T1021 |
23-25 |
CD |
denotes |
80 |
T1022 |
25-26 |
NN |
denotes |
% |
T1023 |
27-29 |
IN |
denotes |
of |
T1024 |
30-33 |
DT |
denotes |
the |
T1025 |
41-49 |
NN |
denotes |
sequence |
T1026 |
34-40 |
NN |
denotes |
coding |
T1027 |
49-51 |
, |
denotes |
, |
T1028 |
51-60 |
VBG |
denotes |
including |
T1029 |
61-64 |
DT |
denotes |
the |
T1030 |
78-84 |
NN |
denotes |
domain |
T1031 |
65-73 |
JJ |
denotes |
critical |
T1032 |
74-77 |
NN |
denotes |
PHD |
T1033 |
84-86 |
, |
denotes |
, |
T1034 |
86-89 |
CC |
denotes |
and |
T1035 |
90-96 |
RB |
denotes |
almost |
T1036 |
97-106 |
RB |
denotes |
certainly |
T1037 |
116-118 |
IN |
denotes |
in |
T1038 |
119-123 |
JJ |
denotes |
null |
T1039 |
124-132 |
NN |
denotes |
function |
T1040 |
132-133 |
. |
denotes |
. |
T1041 |
133-344 |
sentence |
denotes |
Pygo2 homozygous mutants, with rare exception, died shortly after birth, with a phenotype including lens agenesis, growth retardation, altered kidney development, and in some cases exencephaly and cleft palate. |
T1042 |
134-139 |
NN |
denotes |
Pygo2 |
T1043 |
140-150 |
JJ |
denotes |
homozygous |
T1044 |
151-158 |
NNS |
denotes |
mutants |
T1045 |
181-185 |
VBD |
denotes |
died |
T1046 |
158-160 |
, |
denotes |
, |
T1047 |
160-164 |
IN |
denotes |
with |
T1048 |
165-169 |
JJ |
denotes |
rare |
T1049 |
170-179 |
NN |
denotes |
exception |
T1050 |
179-181 |
, |
denotes |
, |
T1051 |
186-193 |
RB |
denotes |
shortly |
T1052 |
194-199 |
IN |
denotes |
after |
T1053 |
200-205 |
NN |
denotes |
birth |
T1054 |
205-207 |
, |
denotes |
, |
T1055 |
207-211 |
IN |
denotes |
with |
T1056 |
212-213 |
DT |
denotes |
a |
T1057 |
214-223 |
NN |
denotes |
phenotype |
T1058 |
224-233 |
VBG |
denotes |
including |
T1059 |
234-238 |
NN |
denotes |
lens |
T1060 |
239-247 |
NN |
denotes |
agenesis |
T1061 |
247-249 |
, |
denotes |
, |
T1062 |
249-255 |
NN |
denotes |
growth |
T1063 |
256-267 |
NN |
denotes |
retardation |
T1064 |
267-269 |
, |
denotes |
, |
T1065 |
269-276 |
VBN |
denotes |
altered |
T1066 |
284-295 |
NN |
denotes |
development |
T1067 |
277-283 |
NN |
denotes |
kidney |
T1068 |
295-297 |
, |
denotes |
, |
T1069 |
297-300 |
CC |
denotes |
and |
T1070 |
301-303 |
IN |
denotes |
in |
T1071 |
315-326 |
NN |
denotes |
exencephaly |
T1072 |
304-308 |
DT |
denotes |
some |
T1073 |
309-314 |
NNS |
denotes |
cases |
T1074 |
327-330 |
CC |
denotes |
and |
T1075 |
331-336 |
VBN |
denotes |
cleft |
T1076 |
337-343 |
NN |
denotes |
palate |
T1077 |
343-344 |
. |
denotes |
. |
T1078 |
344-446 |
sentence |
denotes |
Pygo1 homozygous mutants, however, were viable and fertile, with no detectable developmental defects. |
T1079 |
345-350 |
NN |
denotes |
Pygo1 |
T1080 |
351-361 |
JJ |
denotes |
homozygous |
T1081 |
362-369 |
NNS |
denotes |
mutants |
T1082 |
380-384 |
VBD |
denotes |
were |
T1083 |
369-371 |
, |
denotes |
, |
T1084 |
371-378 |
RB |
denotes |
however |
T1085 |
378-380 |
, |
denotes |
, |
T1086 |
385-391 |
JJ |
denotes |
viable |
T1087 |
392-395 |
CC |
denotes |
and |
T1088 |
396-403 |
JJ |
denotes |
fertile |
T1089 |
403-405 |
, |
denotes |
, |
T1090 |
405-409 |
IN |
denotes |
with |
T1091 |
410-412 |
DT |
denotes |
no |
T1092 |
438-445 |
NNS |
denotes |
defects |
T1093 |
413-423 |
JJ |
denotes |
detectable |
T1094 |
424-437 |
JJ |
denotes |
developmental |
T1095 |
445-446 |
. |
denotes |
. |
T1096 |
446-534 |
sentence |
denotes |
Double Pygo1/Pygo2 homozygous mutants showed no apparent synergy in phenotype severity. |
T1097 |
447-453 |
JJ |
denotes |
Double |
T1098 |
460-465 |
NN |
denotes |
Pygo2 |
T1099 |
454-459 |
NN |
denotes |
Pygo1 |
T1100 |
459-460 |
HYPH |
denotes |
/ |
T1101 |
466-476 |
JJ |
denotes |
homozygous |
T1102 |
477-484 |
NNS |
denotes |
mutants |
T1103 |
485-491 |
VBD |
denotes |
showed |
T1104 |
492-494 |
DT |
denotes |
no |
T1105 |
504-511 |
NN |
denotes |
synergy |
T1106 |
495-503 |
JJ |
denotes |
apparent |
T1107 |
512-514 |
IN |
denotes |
in |
T1108 |
515-524 |
NN |
denotes |
phenotype |
T1109 |
525-533 |
NN |
denotes |
severity |
T1110 |
533-534 |
. |
denotes |
. |
T1111 |
534-714 |
sentence |
denotes |
The BAT-gal transgene reporter of canonical Wnt signaling showed reduced levels of expression in Pygo1-/-/Pygo2-/- mutants, with tissue-specific variation in degree of diminution. |
T1112 |
535-538 |
DT |
denotes |
The |
T1113 |
557-565 |
NN |
denotes |
reporter |
T1114 |
539-542 |
NN |
denotes |
BAT |
T1115 |
543-546 |
NN |
denotes |
gal |
T1116 |
542-543 |
HYPH |
denotes |
- |
T1117 |
547-556 |
NN |
denotes |
transgene |
T1118 |
593-599 |
VBD |
denotes |
showed |
T1119 |
566-568 |
IN |
denotes |
of |
T1120 |
569-578 |
JJ |
denotes |
canonical |
T1121 |
583-592 |
NN |
denotes |
signaling |
T1122 |
579-582 |
NN |
denotes |
Wnt |
T1123 |
600-607 |
VBN |
denotes |
reduced |
T1124 |
608-614 |
NNS |
denotes |
levels |
T1125 |
615-617 |
IN |
denotes |
of |
T1126 |
618-628 |
NN |
denotes |
expression |
T1127 |
629-631 |
IN |
denotes |
in |
T1128 |
632-637 |
NN |
denotes |
Pygo1 |
T1129 |
650-657 |
NNS |
denotes |
mutants |
T1130 |
637-638 |
SYM |
denotes |
- |
T1131 |
638-639 |
HYPH |
denotes |
/ |
T1132 |
639-640 |
SYM |
denotes |
- |
T1133 |
640-641 |
HYPH |
denotes |
/ |
T1134 |
641-646 |
NN |
denotes |
Pygo2 |
T1135 |
646-647 |
SYM |
denotes |
- |
T1136 |
647-648 |
HYPH |
denotes |
/ |
T1137 |
648-649 |
SYM |
denotes |
- |
T1138 |
657-659 |
, |
denotes |
, |
T1139 |
659-663 |
IN |
denotes |
with |
T1140 |
664-670 |
NN |
denotes |
tissue |
T1141 |
671-679 |
JJ |
denotes |
specific |
T1142 |
670-671 |
HYPH |
denotes |
- |
T1143 |
680-689 |
NN |
denotes |
variation |
T1144 |
690-692 |
IN |
denotes |
in |
T1145 |
693-699 |
NN |
denotes |
degree |
T1146 |
700-702 |
IN |
denotes |
of |
T1147 |
703-713 |
NN |
denotes |
diminution |
T1148 |
713-714 |
. |
denotes |
. |
T1149 |
714-852 |
sentence |
denotes |
The Pygo1 and Pygo2 genes both showed widespread expression in the developing kidney, with raised levels in the stromal cell compartment. |
T1150 |
715-718 |
DT |
denotes |
The |
T1151 |
735-740 |
NNS |
denotes |
genes |
T1152 |
719-724 |
NN |
denotes |
Pygo1 |
T1153 |
725-728 |
CC |
denotes |
and |
T1154 |
729-734 |
NN |
denotes |
Pygo2 |
T1155 |
746-752 |
VBD |
denotes |
showed |
T1156 |
741-745 |
RB |
denotes |
both |
T1157 |
753-763 |
JJ |
denotes |
widespread |
T1158 |
764-774 |
NN |
denotes |
expression |
T1159 |
775-777 |
IN |
denotes |
in |
T1160 |
778-781 |
DT |
denotes |
the |
T1161 |
793-799 |
NN |
denotes |
kidney |
T1162 |
782-792 |
VBG |
denotes |
developing |
T1163 |
799-801 |
, |
denotes |
, |
T1164 |
801-805 |
IN |
denotes |
with |
T1165 |
806-812 |
VBN |
denotes |
raised |
T1166 |
813-819 |
NNS |
denotes |
levels |
T1167 |
820-822 |
IN |
denotes |
in |
T1168 |
823-826 |
DT |
denotes |
the |
T1169 |
840-851 |
NN |
denotes |
compartment |
T1170 |
827-834 |
JJ |
denotes |
stromal |
T1171 |
835-839 |
NN |
denotes |
cell |
T1172 |
851-852 |
. |
denotes |
. |
T1173 |
852-992 |
sentence |
denotes |
Confocal analysis of the double mutant kidneys showed disturbance of both the ureteric bud and metanephric mesenchyme-derived compartments. |
T1174 |
853-861 |
JJ |
denotes |
Confocal |
T1175 |
862-870 |
NN |
denotes |
analysis |
T1176 |
900-906 |
VBD |
denotes |
showed |
T1177 |
871-873 |
IN |
denotes |
of |
T1178 |
874-877 |
DT |
denotes |
the |
T1179 |
892-899 |
NNS |
denotes |
kidneys |
T1180 |
878-884 |
JJ |
denotes |
double |
T1181 |
885-891 |
NN |
denotes |
mutant |
T1182 |
907-918 |
NN |
denotes |
disturbance |
T1183 |
919-921 |
IN |
denotes |
of |
T1184 |
922-926 |
CC |
denotes |
both |
T1185 |
979-991 |
NNS |
denotes |
compartments |
T1186 |
927-930 |
DT |
denotes |
the |
T1187 |
931-939 |
JJ |
denotes |
ureteric |
T1188 |
940-943 |
NN |
denotes |
bud |
T1189 |
971-978 |
VBN |
denotes |
derived |
T1190 |
944-947 |
CC |
denotes |
and |
T1191 |
948-959 |
JJ |
denotes |
metanephric |
T1192 |
960-970 |
NN |
denotes |
mesenchyme |
T1193 |
970-971 |
HYPH |
denotes |
- |
T1194 |
991-992 |
. |
denotes |
. |
T1195 |
992-1157 |
sentence |
denotes |
Branching morphogenesis of the ureteric bud was altered, with expanded tips and reduced tip density, probably contributing to the smaller size of the mutant kidney. |
T1196 |
993-1002 |
VBG |
denotes |
Branching |
T1197 |
1003-1016 |
NN |
denotes |
morphogenesis |
T1198 |
1041-1048 |
VBN |
denotes |
altered |
T1199 |
1017-1019 |
IN |
denotes |
of |
T1200 |
1020-1023 |
DT |
denotes |
the |
T1201 |
1033-1036 |
NN |
denotes |
bud |
T1202 |
1024-1032 |
JJ |
denotes |
ureteric |
T1203 |
1037-1040 |
VBD |
denotes |
was |
T1204 |
1048-1050 |
, |
denotes |
, |
T1205 |
1050-1054 |
IN |
denotes |
with |
T1206 |
1055-1063 |
VBN |
denotes |
expanded |
T1207 |
1064-1068 |
NNS |
denotes |
tips |
T1208 |
1069-1072 |
CC |
denotes |
and |
T1209 |
1073-1080 |
VBN |
denotes |
reduced |
T1210 |
1085-1092 |
NN |
denotes |
density |
T1211 |
1081-1084 |
NN |
denotes |
tip |
T1212 |
1092-1094 |
, |
denotes |
, |
T1213 |
1094-1102 |
RB |
denotes |
probably |
T1214 |
1103-1115 |
VBG |
denotes |
contributing |
T1215 |
1116-1118 |
IN |
denotes |
to |
T1216 |
1119-1122 |
DT |
denotes |
the |
T1217 |
1131-1135 |
NN |
denotes |
size |
T1218 |
1123-1130 |
JJR |
denotes |
smaller |
T1219 |
1136-1138 |
IN |
denotes |
of |
T1220 |
1139-1142 |
DT |
denotes |
the |
T1221 |
1150-1156 |
NN |
denotes |
kidney |
T1222 |
1143-1149 |
NN |
denotes |
mutant |
T1223 |
1156-1157 |
. |
denotes |
. |
T1224 |
1157-1255 |
sentence |
denotes |
In addition, there was an expansion of the zone of condensed mesenchyme capping the ureteric bud. |
T1225 |
1158-1160 |
IN |
denotes |
In |
T1226 |
1177-1180 |
VBD |
denotes |
was |
T1227 |
1161-1169 |
NN |
denotes |
addition |
T1228 |
1169-1171 |
, |
denotes |
, |
T1229 |
1171-1176 |
EX |
denotes |
there |
T1230 |
1181-1183 |
DT |
denotes |
an |
T1231 |
1184-1193 |
NN |
denotes |
expansion |
T1232 |
1194-1196 |
IN |
denotes |
of |
T1233 |
1197-1200 |
DT |
denotes |
the |
T1234 |
1201-1205 |
NN |
denotes |
zone |
T1235 |
1206-1208 |
IN |
denotes |
of |
T1236 |
1209-1218 |
VBN |
denotes |
condensed |
T1237 |
1219-1229 |
NN |
denotes |
mesenchyme |
T1238 |
1230-1237 |
VBG |
denotes |
capping |
T1239 |
1238-1241 |
DT |
denotes |
the |
T1240 |
1251-1254 |
NN |
denotes |
bud |
T1241 |
1242-1250 |
JJ |
denotes |
ureteric |
T1242 |
1254-1255 |
. |
denotes |
. |
T1243 |
1255-1303 |
sentence |
denotes |
Nephron formation, however, proceeded normally. |
T1244 |
1256-1263 |
NN |
denotes |
Nephron |
T1245 |
1264-1273 |
NN |
denotes |
formation |
T1246 |
1284-1293 |
VBD |
denotes |
proceeded |
T1247 |
1273-1275 |
, |
denotes |
, |
T1248 |
1275-1282 |
RB |
denotes |
however |
T1249 |
1282-1284 |
, |
denotes |
, |
T1250 |
1294-1302 |
RB |
denotes |
normally |
T1251 |
1302-1303 |
. |
denotes |
. |
T1252 |
1303-1479 |
sentence |
denotes |
Microarray analysis showed changed expression of several genes, including Cxcl13, Slc5a2, Klk5, Ren2 and Timeless, which represent candidate Wnt targets in kidney development. |
T1253 |
1304-1314 |
NN |
denotes |
Microarray |
T1254 |
1315-1323 |
NN |
denotes |
analysis |
T1255 |
1324-1330 |
VBD |
denotes |
showed |
T1256 |
1331-1338 |
VBN |
denotes |
changed |
T1257 |
1339-1349 |
NN |
denotes |
expression |
T1258 |
1350-1352 |
IN |
denotes |
of |
T1259 |
1353-1360 |
JJ |
denotes |
several |
T1260 |
1361-1366 |
NNS |
denotes |
genes |
T1261 |
1366-1368 |
, |
denotes |
, |
T1262 |
1368-1377 |
VBG |
denotes |
including |
T1263 |
1378-1384 |
NN |
denotes |
Cxcl13 |
T1264 |
1384-1386 |
, |
denotes |
, |
T1265 |
1386-1392 |
NN |
denotes |
Slc5a2 |
T1266 |
1392-1394 |
, |
denotes |
, |
T1267 |
1394-1398 |
NN |
denotes |
Klk5 |
T1268 |
1398-1400 |
, |
denotes |
, |
T1269 |
1400-1404 |
NN |
denotes |
Ren2 |
T1270 |
1405-1408 |
CC |
denotes |
and |
T1271 |
1409-1417 |
NN |
denotes |
Timeless |
T1272 |
1417-1419 |
, |
denotes |
, |
T1273 |
1419-1424 |
WDT |
denotes |
which |
T1274 |
1425-1434 |
VBP |
denotes |
represent |
T1275 |
1435-1444 |
NN |
denotes |
candidate |
T1276 |
1449-1456 |
NNS |
denotes |
targets |
T1277 |
1445-1448 |
NN |
denotes |
Wnt |
T1278 |
1457-1459 |
IN |
denotes |
in |
T1279 |
1460-1466 |
NN |
denotes |
kidney |
T1280 |
1467-1478 |
NN |
denotes |
development |
T1281 |
1478-1479 |
. |
denotes |
. |
R67 |
T1016 |
T1017 |
det |
Each,mutation |
R68 |
T1017 |
T1018 |
nsubj |
mutation,resulted |
R69 |
T1019 |
T1018 |
aux |
deleted,resulted |
R70 |
T1020 |
T1021 |
punct |
>,80 |
R71 |
T1021 |
T1022 |
nummod |
80,% |
R72 |
T1022 |
T1018 |
dobj |
%,resulted |
R73 |
T1023 |
T1022 |
prep |
of,% |
R74 |
T1024 |
T1025 |
det |
the,sequence |
R75 |
T1025 |
T1023 |
pobj |
sequence,of |
R76 |
T1026 |
T1025 |
compound |
coding,sequence |
R77 |
T1027 |
T1022 |
punct |
", ",% |
R78 |
T1028 |
T1022 |
prep |
including,% |
R79 |
T1029 |
T1030 |
det |
the,domain |
R80 |
T1030 |
T1028 |
pobj |
domain,including |
R81 |
T1031 |
T1030 |
amod |
critical,domain |
R82 |
T1032 |
T1030 |
compound |
PHD,domain |
R83 |
T1033 |
T1018 |
punct |
", ",resulted |
R84 |
T1034 |
T1018 |
cc |
and,resulted |
R85 |
T1035 |
T1036 |
advmod |
almost,certainly |
R86 |
T1036 |
T1018 |
advmod |
certainly,resulted |
R87 |
T1037 |
T1018 |
prep |
in,resulted |
R88 |
T1038 |
T1039 |
amod |
null,function |
R89 |
T1039 |
T1037 |
pobj |
function,in |
R90 |
T1040 |
T1018 |
punct |
.,resulted |
R91 |
T1042 |
T1043 |
npadvmod |
Pygo2,homozygous |
R92 |
T1043 |
T1044 |
amod |
homozygous,mutants |
R93 |
T1044 |
T1045 |
nsubj |
mutants,died |
R94 |
T1046 |
T1045 |
punct |
", ",died |
R95 |
T1047 |
T1045 |
prep |
with,died |
R96 |
T1048 |
T1049 |
amod |
rare,exception |
R97 |
T1049 |
T1047 |
pobj |
exception,with |
R98 |
T1050 |
T1045 |
punct |
", ",died |
R99 |
T1051 |
T1052 |
advmod |
shortly,after |
R100 |
T1052 |
T1045 |
prep |
after,died |
R101 |
T1053 |
T1052 |
pobj |
birth,after |
R102 |
T1054 |
T1045 |
punct |
", ",died |
R103 |
T1055 |
T1045 |
prep |
with,died |
R104 |
T1056 |
T1057 |
det |
a,phenotype |
R105 |
T1057 |
T1055 |
pobj |
phenotype,with |
R106 |
T1058 |
T1057 |
prep |
including,phenotype |
R107 |
T1059 |
T1060 |
compound |
lens,agenesis |
R108 |
T1060 |
T1058 |
pobj |
agenesis,including |
R109 |
T1061 |
T1060 |
punct |
", ",agenesis |
R110 |
T1062 |
T1063 |
compound |
growth,retardation |
R111 |
T1063 |
T1060 |
conj |
retardation,agenesis |
R112 |
T1064 |
T1063 |
punct |
", ",retardation |
R113 |
T1065 |
T1066 |
amod |
altered,development |
R114 |
T1066 |
T1063 |
conj |
development,retardation |
R115 |
T1067 |
T1066 |
compound |
kidney,development |
R116 |
T1068 |
T1066 |
punct |
", ",development |
R117 |
T1069 |
T1066 |
cc |
and,development |
R118 |
T1070 |
T1071 |
prep |
in,exencephaly |
R119 |
T1071 |
T1066 |
conj |
exencephaly,development |
R120 |
T1072 |
T1073 |
det |
some,cases |
R121 |
T1073 |
T1070 |
pobj |
cases,in |
R122 |
T1074 |
T1071 |
cc |
and,exencephaly |
R123 |
T1075 |
T1076 |
amod |
cleft,palate |
R124 |
T1076 |
T1071 |
conj |
palate,exencephaly |
R125 |
T1077 |
T1045 |
punct |
.,died |
R126 |
T1079 |
T1080 |
npadvmod |
Pygo1,homozygous |
R127 |
T1080 |
T1081 |
amod |
homozygous,mutants |
R128 |
T1081 |
T1082 |
nsubj |
mutants,were |
R129 |
T1083 |
T1082 |
punct |
", ",were |
R130 |
T1084 |
T1082 |
advmod |
however,were |
R131 |
T1085 |
T1082 |
punct |
", ",were |
R132 |
T1086 |
T1082 |
acomp |
viable,were |
R133 |
T1087 |
T1086 |
cc |
and,viable |
R134 |
T1088 |
T1086 |
conj |
fertile,viable |
R135 |
T1089 |
T1082 |
punct |
", ",were |
R136 |
T1090 |
T1082 |
prep |
with,were |
R137 |
T1091 |
T1092 |
det |
no,defects |
R138 |
T1092 |
T1090 |
pobj |
defects,with |
R139 |
T1093 |
T1092 |
amod |
detectable,defects |
R140 |
T1094 |
T1092 |
amod |
developmental,defects |
R141 |
T1095 |
T1082 |
punct |
.,were |
R142 |
T1097 |
T1098 |
amod |
Double,Pygo2 |
R143 |
T1098 |
T1101 |
npadvmod |
Pygo2,homozygous |
R144 |
T1099 |
T1098 |
compound |
Pygo1,Pygo2 |
R145 |
T1100 |
T1098 |
punct |
/,Pygo2 |
R146 |
T1101 |
T1102 |
amod |
homozygous,mutants |
R147 |
T1102 |
T1103 |
nsubj |
mutants,showed |
R148 |
T1104 |
T1105 |
det |
no,synergy |
R149 |
T1105 |
T1103 |
dobj |
synergy,showed |
R150 |
T1106 |
T1105 |
amod |
apparent,synergy |
R151 |
T1107 |
T1105 |
prep |
in,synergy |
R152 |
T1108 |
T1109 |
compound |
phenotype,severity |
R153 |
T1109 |
T1107 |
pobj |
severity,in |
R154 |
T1110 |
T1103 |
punct |
.,showed |
R155 |
T1112 |
T1113 |
det |
The,reporter |
R156 |
T1113 |
T1118 |
nsubj |
reporter,showed |
R157 |
T1114 |
T1115 |
compound |
BAT,gal |
R158 |
T1115 |
T1117 |
compound |
gal,transgene |
R159 |
T1116 |
T1115 |
punct |
-,gal |
R160 |
T1117 |
T1113 |
compound |
transgene,reporter |
R161 |
T1119 |
T1113 |
prep |
of,reporter |
R162 |
T1120 |
T1121 |
amod |
canonical,signaling |
R163 |
T1121 |
T1119 |
pobj |
signaling,of |
R164 |
T1122 |
T1121 |
compound |
Wnt,signaling |
R165 |
T1123 |
T1124 |
amod |
reduced,levels |
R166 |
T1124 |
T1118 |
dobj |
levels,showed |
R167 |
T1125 |
T1124 |
prep |
of,levels |
R168 |
T1126 |
T1125 |
pobj |
expression,of |
R169 |
T1127 |
T1124 |
prep |
in,levels |
R170 |
T1128 |
T1129 |
nmod |
Pygo1,mutants |
R171 |
T1129 |
T1127 |
pobj |
mutants,in |
R172 |
T1130 |
T1128 |
punct |
-,Pygo1 |
R173 |
T1131 |
T1128 |
punct |
/,Pygo1 |
R174 |
T1132 |
T1128 |
punct |
-,Pygo1 |
R175 |
T1133 |
T1128 |
punct |
/,Pygo1 |
R176 |
T1134 |
T1128 |
appos |
Pygo2,Pygo1 |
R177 |
T1135 |
T1134 |
punct |
-,Pygo2 |
R178 |
T1136 |
T1134 |
punct |
/,Pygo2 |
R179 |
T1137 |
T1134 |
punct |
-,Pygo2 |
R180 |
T1138 |
T1118 |
punct |
", ",showed |
R181 |
T1139 |
T1118 |
prep |
with,showed |
R182 |
T1140 |
T1141 |
npadvmod |
tissue,specific |
R183 |
T1141 |
T1143 |
amod |
specific,variation |
R184 |
T1142 |
T1141 |
punct |
-,specific |
R185 |
T1143 |
T1139 |
pobj |
variation,with |
R186 |
T1144 |
T1143 |
prep |
in,variation |
R187 |
T1145 |
T1144 |
pobj |
degree,in |
R188 |
T1146 |
T1145 |
prep |
of,degree |
R189 |
T1147 |
T1146 |
pobj |
diminution,of |
R190 |
T1148 |
T1118 |
punct |
.,showed |
R191 |
T1150 |
T1151 |
det |
The,genes |
R193 |
T1152 |
T1151 |
nmod |
Pygo1,genes |
R194 |
T1153 |
T1152 |
cc |
and,Pygo1 |
R195 |
T1154 |
T1152 |
conj |
Pygo2,Pygo1 |
R196 |
T1156 |
T1151 |
appos |
both,genes |
R197 |
T1157 |
T1158 |
amod |
widespread,expression |
R198 |
T1158 |
T1155 |
dobj |
expression,showed |
R199 |
T1159 |
T1158 |
prep |
in,expression |
R200 |
T1160 |
T1161 |
det |
the,kidney |
R201 |
T1161 |
T1159 |
pobj |
kidney,in |
R202 |
T1162 |
T1161 |
amod |
developing,kidney |
R203 |
T1163 |
T1155 |
punct |
", ",showed |
R204 |
T1164 |
T1155 |
prep |
with,showed |
R205 |
T1165 |
T1166 |
amod |
raised,levels |
R206 |
T1166 |
T1164 |
pobj |
levels,with |
R207 |
T1167 |
T1166 |
prep |
in,levels |
R208 |
T1168 |
T1169 |
det |
the,compartment |
R209 |
T1169 |
T1167 |
pobj |
compartment,in |
R210 |
T1170 |
T1171 |
amod |
stromal,cell |
R211 |
T1171 |
T1169 |
compound |
cell,compartment |
R212 |
T1172 |
T1155 |
punct |
.,showed |
R213 |
T1174 |
T1175 |
amod |
Confocal,analysis |
R214 |
T1175 |
T1176 |
nsubj |
analysis,showed |
R215 |
T1177 |
T1175 |
prep |
of,analysis |
R216 |
T1178 |
T1179 |
det |
the,kidneys |
R217 |
T1179 |
T1177 |
pobj |
kidneys,of |
R218 |
T1180 |
T1181 |
amod |
double,mutant |
R219 |
T1181 |
T1179 |
compound |
mutant,kidneys |
R220 |
T1182 |
T1176 |
dobj |
disturbance,showed |
R221 |
T1183 |
T1182 |
prep |
of,disturbance |
R222 |
T1184 |
T1185 |
preconj |
both,compartments |
R223 |
T1185 |
T1183 |
pobj |
compartments,of |
R224 |
T1186 |
T1185 |
det |
the,compartments |
R225 |
T1187 |
T1188 |
amod |
ureteric,bud |
R226 |
T1188 |
T1189 |
npadvmod |
bud,derived |
R228 |
T1190 |
T1188 |
cc |
and,bud |
R229 |
T1191 |
T1192 |
amod |
metanephric,mesenchyme |
R230 |
T1192 |
T1188 |
conj |
mesenchyme,bud |
R231 |
T1193 |
T1189 |
punct |
-,derived |
R232 |
T1194 |
T1176 |
punct |
.,showed |
R233 |
T1196 |
T1197 |
amod |
Branching,morphogenesis |
R234 |
T1197 |
T1198 |
nsubjpass |
morphogenesis,altered |
R235 |
T1199 |
T1197 |
prep |
of,morphogenesis |
R236 |
T1200 |
T1201 |
det |
the,bud |
R237 |
T1201 |
T1199 |
pobj |
bud,of |
R238 |
T1202 |
T1201 |
amod |
ureteric,bud |
R239 |
T1203 |
T1198 |
auxpass |
was,altered |
R240 |
T1204 |
T1198 |
punct |
", ",altered |
R241 |
T1205 |
T1198 |
prep |
with,altered |
R242 |
T1206 |
T1207 |
amod |
expanded,tips |
R243 |
T1207 |
T1205 |
pobj |
tips,with |
R244 |
T1208 |
T1207 |
cc |
and,tips |
R245 |
T1209 |
T1210 |
amod |
reduced,density |
R246 |
T1210 |
T1207 |
conj |
density,tips |
R247 |
T1211 |
T1210 |
compound |
tip,density |
R248 |
T1212 |
T1198 |
punct |
", ",altered |
R249 |
T1213 |
T1214 |
advmod |
probably,contributing |
R250 |
T1214 |
T1198 |
advcl |
contributing,altered |
R251 |
T1215 |
T1214 |
prep |
to,contributing |
R252 |
T1216 |
T1217 |
det |
the,size |
R253 |
T1217 |
T1215 |
pobj |
size,to |
R254 |
T1218 |
T1217 |
amod |
smaller,size |
R255 |
T1219 |
T1217 |
prep |
of,size |
R256 |
T1220 |
T1221 |
det |
the,kidney |
R257 |
T1221 |
T1219 |
pobj |
kidney,of |
R258 |
T1222 |
T1221 |
compound |
mutant,kidney |
R259 |
T1223 |
T1198 |
punct |
.,altered |
R260 |
T1225 |
T1226 |
prep |
In,was |
R261 |
T1227 |
T1225 |
pobj |
addition,In |
R262 |
T1228 |
T1226 |
punct |
", ",was |
R263 |
T1229 |
T1226 |
expl |
there,was |
R264 |
T1230 |
T1231 |
det |
an,expansion |
R265 |
T1231 |
T1226 |
attr |
expansion,was |
R266 |
T1232 |
T1231 |
prep |
of,expansion |
R267 |
T1233 |
T1234 |
det |
the,zone |
R268 |
T1234 |
T1232 |
pobj |
zone,of |
R269 |
T1235 |
T1234 |
prep |
of,zone |
R270 |
T1236 |
T1237 |
amod |
condensed,mesenchyme |
R271 |
T1237 |
T1235 |
pobj |
mesenchyme,of |
R272 |
T1238 |
T1234 |
acl |
capping,zone |
R273 |
T1239 |
T1240 |
det |
the,bud |
R274 |
T1240 |
T1238 |
dobj |
bud,capping |
R275 |
T1241 |
T1240 |
amod |
ureteric,bud |
R276 |
T1242 |
T1226 |
punct |
.,was |
R277 |
T1244 |
T1245 |
compound |
Nephron,formation |
R278 |
T1245 |
T1246 |
nsubj |
formation,proceeded |
R279 |
T1247 |
T1246 |
punct |
", ",proceeded |
R280 |
T1248 |
T1246 |
advmod |
however,proceeded |
R281 |
T1249 |
T1246 |
punct |
", ",proceeded |
R282 |
T1250 |
T1246 |
advmod |
normally,proceeded |
R283 |
T1251 |
T1246 |
punct |
.,proceeded |
R284 |
T1253 |
T1254 |
compound |
Microarray,analysis |
R285 |
T1254 |
T1255 |
nsubj |
analysis,showed |
R286 |
T1256 |
T1257 |
amod |
changed,expression |
R287 |
T1257 |
T1255 |
dobj |
expression,showed |
R288 |
T1258 |
T1257 |
prep |
of,expression |
R289 |
T1259 |
T1260 |
amod |
several,genes |
R290 |
T1260 |
T1258 |
pobj |
genes,of |
R291 |
T1261 |
T1260 |
punct |
", ",genes |
R292 |
T1262 |
T1260 |
prep |
including,genes |
R293 |
T1263 |
T1262 |
pobj |
Cxcl13,including |
R294 |
T1264 |
T1263 |
punct |
", ",Cxcl13 |
R295 |
T1265 |
T1263 |
conj |
Slc5a2,Cxcl13 |
R296 |
T1266 |
T1265 |
punct |
", ",Slc5a2 |
R297 |
T1267 |
T1265 |
conj |
Klk5,Slc5a2 |
R298 |
T1268 |
T1267 |
punct |
", ",Klk5 |
R299 |
T1269 |
T1267 |
conj |
Ren2,Klk5 |
R300 |
T1270 |
T1269 |
cc |
and,Ren2 |
R301 |
T1271 |
T1269 |
conj |
Timeless,Ren2 |
R302 |
T1272 |
T1260 |
punct |
", ",genes |
R303 |
T1273 |
T1274 |
dep |
which,represent |
R304 |
T1274 |
T1260 |
relcl |
represent,genes |
R305 |
T1275 |
T1276 |
compound |
candidate,targets |
R306 |
T1276 |
T1274 |
dobj |
targets,represent |
R307 |
T1277 |
T1276 |
compound |
Wnt,targets |
R308 |
T1278 |
T1276 |
prep |
in,targets |
R309 |
T1279 |
T1280 |
compound |
kidney,development |
R310 |
T1280 |
T1278 |
pobj |
development,in |
R311 |
T1281 |
T1255 |
punct |
.,showed |
R192 |
T1151 |
T1155 |
nsubj |
genes,showed |
R227 |
T1189 |
T1185 |
amod |
derived,compartments |