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PMC:1858683 / 28512-29187 JSONTXT

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Id Subject Object Predicate Lexical cue
T27371 513-524 VB denotes demonstrate
T27370 510-512 TO denotes to
T27369 496-500 VBD denotes were
T27368 501-509 VBN denotes included
T27367 483-488 NN denotes Pygo2
T27366 479-482 CC denotes and
T27365 489-495 NNS denotes probes
T27364 473-478 NN denotes Pygo1
T27363 472-566 sentence denotes Pygo1 and Pygo2 probes were included to demonstrate significant changes in expression levels.
T27362 471-472 . denotes .
T27361 464-471 NNS denotes samples
T27360 456-461 RBS denotes least
T27359 462-463 CD denotes 3
T27358 453-455 RB denotes at
T27357 450-452 IN denotes in
T27356 446-449 CD denotes 100
T27355 445-446 SYM denotes >
T27354 442-444 VB denotes be
T27353 439-441 TO denotes to
T27352 418-428 NN denotes expression
T27351 414-417 JJ denotes raw
T27350 429-438 NN denotes intensity
T27349 410-413 DT denotes the
T27348 400-409 VBG denotes requiring
T27347 382-387 NN denotes level
T27346 371-381 NN denotes expression
T27345 388-399 NN denotes restriction
T27344 368-370 DT denotes an
T27343 362-367 VBG denotes using
T27342 356-361 NNS denotes genes
T27341 353-355 CD denotes 40
T27340 350-352 IN denotes of
T27339 344-349 NN denotes total
T27338 342-343 DT denotes a
T27337 339-341 IN denotes to
T27336 331-338 VBN denotes reduced
T27335 326-330 RB denotes then
T27334 322-325 CC denotes and
T27333 310-313 VBD denotes was
T27332 298-301 NN denotes Wnt
T27331 302-309 NNS denotes targets
T27330 295-297 CD denotes 82
T27329 292-294 IN denotes of
T27328 314-321 VBN denotes created
T27327 282-286 NN denotes gene
T27326 274-281 JJ denotes initial
T27325 287-291 NN denotes list
T27324 271-273 DT denotes An
T27323 270-472 sentence denotes An initial gene list of 82 Wnt targets was created and then reduced to a total of 40 genes using an expression level restriction requiring the raw expression intensity to be >100 in at least 3 samples.
T27322 269-270 . denotes .
T27321 268-269 -RRB- denotes ]
T27320 266-268 CD denotes 39
T27319 265-266 -LRB- denotes [
T27318 262-264 IN denotes at
T27317 253-261 VBN denotes compiled
T27316 247-252 DT denotes those
T27310 207-215 JJ denotes Possible
T27309 206-270 sentence denotes Possible Wnt targets were selected from those compiled at [39].
T27308 205-206 . denotes .
T27307 192-197 NN denotes E18.5
T27306 178-186 NN denotes compound
T27305 176-177 CD denotes 2
T27304 175-176 HYPH denotes /
T27303 187-191 JJ denotes null
T27302 170-175 NN denotes Pygo1
T27301 166-169 CC denotes and
T27300 198-205 NNS denotes kidneys
T27299 160-161 HYPH denotes -
T27298 161-165 NN denotes type
T27297 156-160 JJ denotes wild
T27296 153-155 IN denotes on
T27295 142-152 NN denotes triplicate
T27294 139-141 IN denotes in
T27293 125-128 VBD denotes was
T27292 129-138 VBN denotes performed
T27291 116-124 NN denotes analysis
T27290 105-115 NN denotes Microarray
T27289 104-206 sentence denotes Microarray analysis was performed in triplicate on wild-type and Pygo1/2 compound null E18.5 kidneys.
T27288 103-104 . denotes .
T27287 92-96 JJ denotes null
T27286 85-86 HYPH denotes /
T27285 86-91 NN denotes Pygo2
T27284 80-85 NN denotes Pygo1
T27283 74-79 NN denotes E18.5
T27282 97-103 NN denotes kidney
T27281 70-73 DT denotes the
T27280 67-69 IN denotes in
T27279 49-58 NN denotes signaling
T27278 45-48 NN denotes Wnt
T27277 59-66 NNS denotes targets
T27276 38-44 JJ denotes common
T27275 35-37 IN denotes of
T27274 27-34 NNS denotes changes
T27273 16-26 NN denotes expression
T27272 11-15 NN denotes Gene
T27315 242-246 IN denotes from
T27314 228-232 VBD denotes were
T27313 233-241 VBN denotes selected
T27312 216-219 NN denotes Wnt
T27311 220-227 NNS denotes targets
T27377 565-566 . denotes .
T27376 559-565 NNS denotes levels
T27375 548-558 NN denotes expression
T27374 545-547 IN denotes in
T27373 537-544 NNS denotes changes
T27372 525-536 JJ denotes significant
T12614 575-587 JJ denotes quantitative
T12613 570-574 VBD denotes used
T12612 567-569 PRP denotes We
T12611 0-675 sentence denotes Figure 8 Gene expression changes of common Wnt signaling targets in the E18.5 Pygo1/Pygo2 null kidney. Microarray analysis was performed in triplicate on wild-type and Pygo1/2 compound null E18.5 kidneys. Possible Wnt targets were selected from those compiled at [39]. An initial gene list of 82 Wnt targets was created and then reduced to a total of 40 genes using an expression level restriction requiring the raw expression intensity to be >100 in at least 3 samples. Pygo1 and Pygo2 probes were included to demonstrate significant changes in expression levels. We used quantitative real-time PCR, with independent biological samples, to validate the microarray results.
T12630 674-675 . denotes .
T12629 656-666 NN denotes microarray
T12628 667-674 NNS denotes results
T12627 652-655 DT denotes the
T12626 643-651 VB denotes validate
T12625 640-642 TO denotes to
T12624 638-640 , denotes ,
T12623 620-630 JJ denotes biological
T12622 631-638 NNS denotes samples
T12621 608-619 JJ denotes independent
T12620 603-607 IN denotes with
T12619 601-603 , denotes ,
T12618 592-593 HYPH denotes -
T12617 593-597 NN denotes time
T12616 588-592 JJ denotes real
T12615 598-601 NN denotes PCR
R7885 T27272 T27273 compound Gene,expression
R7886 T27273 T27274 compound expression,changes
R7887 T27275 T27274 prep of,changes
R7888 T27276 T27277 amod common,targets
R7889 T27277 T27275 pobj targets,of
R7890 T27278 T27277 compound Wnt,targets
R7891 T27279 T27277 compound signaling,targets
R7892 T27280 T27274 prep in,changes
R7893 T27281 T27282 det the,kidney
R7894 T27282 T27280 pobj kidney,in
R7895 T27283 T27282 nmod E18.5,kidney
R7896 T27284 T27285 compound Pygo1,Pygo2
R7897 T27285 T27287 npadvmod Pygo2,null
R7898 T27286 T27285 punct /,Pygo2
R7899 T27287 T27282 amod null,kidney
R7900 T27288 T27274 punct .,changes
R7901 T27290 T27291 compound Microarray,analysis
R7902 T27291 T27292 nsubjpass analysis,performed
R7903 T27293 T27292 auxpass was,performed
R7904 T27294 T27292 prep in,performed
R7905 T27295 T27294 pobj triplicate,in
R7906 T27296 T27292 prep on,performed
R7907 T27297 T27298 amod wild,type
R7908 T27298 T27300 nmod type,kidneys
R7909 T27299 T27298 punct -,type
R7910 T27300 T27296 pobj kidneys,on
R7911 T27301 T27298 cc and,type
R7912 T27302 T27303 npadvmod Pygo1,null
R7913 T27303 T27298 conj null,type
R7914 T27304 T27302 punct /,Pygo1
R7915 T27305 T27302 nummod 2,Pygo1
R7916 T27306 T27303 npadvmod compound,null
R7917 T27307 T27300 compound E18.5,kidneys
R7918 T27308 T27292 punct .,performed
R7919 T27310 T27311 amod Possible,targets
R7920 T27311 T27313 nsubjpass targets,selected
R7921 T27312 T27311 compound Wnt,targets
R7922 T27314 T27313 auxpass were,selected
R7923 T27315 T27313 prep from,selected
R7924 T27316 T27315 pobj those,from
R7925 T27317 T27316 acl compiled,those
R7926 T27318 T27317 prep at,compiled
R7927 T27319 T27318 punct [,at
R7928 T27320 T27318 pobj 39,at
R7929 T27321 T27313 punct ],selected
R7930 T27322 T27313 punct .,selected
R7931 T27324 T27325 det An,list
R7932 T27325 T27328 nsubjpass list,created
R7933 T27326 T27325 amod initial,list
R7934 T27327 T27325 compound gene,list
R7935 T27329 T27325 prep of,list
R7936 T27330 T27331 nummod 82,targets
R7937 T27331 T27329 pobj targets,of
R7938 T27332 T27331 compound Wnt,targets
R7939 T27333 T27328 auxpass was,created
R7940 T27334 T27328 cc and,created
R7941 T27335 T27336 advmod then,reduced
R7942 T27336 T27328 conj reduced,created
R7943 T27337 T27336 prep to,reduced
R7944 T27338 T27339 det a,total
R7945 T27339 T27337 pobj total,to
R7946 T27340 T27339 prep of,total
R7947 T27341 T27342 nummod 40,genes
R7948 T27342 T27340 pobj genes,of
R7949 T27343 T27336 advcl using,reduced
R7950 T27344 T27345 det an,restriction
R7951 T27345 T27343 dobj restriction,using
R7952 T27346 T27347 compound expression,level
R7953 T27347 T27345 compound level,restriction
R7954 T27348 T27345 acl requiring,restriction
R7955 T27349 T27350 det the,intensity
R7956 T27350 T27348 dobj intensity,requiring
R7957 T27351 T27350 amod raw,intensity
R7958 T27352 T27350 compound expression,intensity
R7959 T27353 T27354 aux to,be
R7960 T27354 T27348 xcomp be,requiring
R7961 T27355 T27356 punct >,100
R7962 T27356 T27354 attr 100,be
R7963 T27357 T27354 prep in,be
R7964 T27358 T27359 advmod at,3
R7965 T27359 T27361 nummod 3,samples
R7966 T27360 T27359 advmod least,3
R7967 T27361 T27357 pobj samples,in
R7968 T27362 T27328 punct .,created
R7969 T27364 T27365 nmod Pygo1,probes
R7970 T27365 T27368 nsubjpass probes,included
R7971 T27366 T27364 cc and,Pygo1
R7972 T27367 T27364 conj Pygo2,Pygo1
R7973 T27369 T27368 auxpass were,included
R7974 T27370 T27371 aux to,demonstrate
R7975 T27371 T27368 advcl demonstrate,included
R7976 T27372 T27373 amod significant,changes
R7977 T27373 T27371 dobj changes,demonstrate
R7978 T27374 T27373 prep in,changes
R7979 T27375 T27376 compound expression,levels
R7980 T27376 T27374 pobj levels,in
R7981 T27377 T27368 punct .,included
R3545 T12612 T12613 nsubj We,used
R3546 T12614 T12615 amod quantitative,PCR
R3547 T12615 T12613 dobj PCR,used
R3548 T12616 T12617 amod real,time
R3549 T12617 T12615 compound time,PCR
R3550 T12618 T12617 punct -,time
R3551 T12619 T12615 punct ", ",PCR
R3552 T12620 T12615 prep with,PCR
R3553 T12621 T12622 amod independent,samples
R3554 T12622 T12620 pobj samples,with
R3555 T12623 T12622 amod biological,samples
R3556 T12624 T12613 punct ", ",used
R3557 T12625 T12626 aux to,validate
R3558 T12626 T12613 advcl validate,used
R3559 T12627 T12628 det the,results
R3560 T12628 T12626 dobj results,validate
R3561 T12629 T12628 compound microarray,results
R3562 T12630 T12613 punct .,used

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T27271 548-558 GO:0010467 denotes expression
T27270 489-495 CHEBI_SO_EXT:molecular_probe denotes probes
T27269 483-488 PR_EXT:000013524 denotes Pygo2
T27268 473-478 PR_EXT:000013523 denotes Pygo1
T27267 418-428 GO:0010467 denotes expression
T27266 356-361 SO_EXT:0000704 denotes genes
T27265 282-286 SO_EXT:0000704 denotes gene
T27264 198-205 UBERON:0002113 denotes kidneys
T27263 187-191 SO_EXT:sequence_nullness denotes null
T27262 170-175 PR_EXT:000013523 denotes Pygo1
T27261 156-165 SO_EXT:wild_type_entity_or_quality denotes wild-type
T27260 97-103 UBERON:0002113 denotes kidney
T27259 92-96 SO_EXT:sequence_nullness denotes null
T27258 86-91 PR_EXT:000013524 denotes Pygo2
T27257 80-85 PR_EXT:000013523 denotes Pygo1
T27256 45-58 GO:0016055 denotes Wnt signaling
T27255 11-26 GO:0010467 denotes Gene expression
T27254 11-15 SO_EXT:0000704 denotes Gene
T27253 371-381 GO:0010467 denotes expression
T12036 620-630 CHEBI_GO_EXT:biological_process_or_quality_or_role denotes biological

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T27241 80-85 PR:000013523 denotes Pygo1
T27240 45-58 GO:0016055 denotes Wnt signaling
T27239 11-26 GO:0010467 denotes Gene expression
T27238 11-15 SO:0000704 denotes Gene
T27252 548-558 GO:0010467 denotes expression
T27251 483-488 PR:000013524 denotes Pygo2
T27250 473-478 PR:000013523 denotes Pygo1
T27249 418-428 GO:0010467 denotes expression
T27248 371-381 GO:0010467 denotes expression
T27247 356-361 SO:0000704 denotes genes
T27246 282-286 SO:0000704 denotes gene
T27245 198-205 UBERON:0002113 denotes kidneys
T27244 170-175 PR:000013523 denotes Pygo1
T27243 97-103 UBERON:0002113 denotes kidney
T27242 86-91 PR:000013524 denotes Pygo2