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PMC:1858683 / 0-675 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T944 6-9 CC denotes and
T945 10-15 NN denotes Pygo2
T946 22-24 IN denotes in
T947 25-28 NN denotes Wnt
T948 29-38 NN denotes signaling
T949 39-41 IN denotes in
T950 42-51 JJ denotes mammalian
T951 52-58 NN denotes kidney
T952 59-70 NN denotes development
T953 70-71 sentence denotes
T954 81-91 sentence denotes Background
T955 81-91 NN denotes Background
T956 91-239 sentence denotes The pygopus gene of Drosophila encodes an essential component of the Armadillo (β-catenin) transcription factor complex of canonical Wnt signaling.
T957 92-95 DT denotes The
T958 104-108 NN denotes gene
T959 96-103 NN denotes pygopus
T960 123-130 VBZ denotes encodes
T961 109-111 IN denotes of
T962 112-122 NNP denotes Drosophila
T963 131-133 DT denotes an
T964 144-153 NN denotes component
T965 134-143 JJ denotes essential
T966 154-156 IN denotes of
T967 157-160 DT denotes the
T968 204-211 NN denotes complex
T969 161-170 NN denotes Armadillo
T970 197-203 NN denotes factor
T971 171-172 -LRB- denotes (
T972 174-181 NN denotes catenin
T973 172-173 NN denotes β
T974 173-174 HYPH denotes -
T975 181-182 -RRB- denotes )
T976 183-196 NN denotes transcription
T977 212-214 IN denotes of
T978 215-224 JJ denotes canonical
T979 229-238 NN denotes signaling
T980 225-228 NN denotes Wnt
T981 238-239 . denotes .
T982 239-419 sentence denotes To better understand the functions of Pygopus-mediated canonical Wnt signaling in kidney development, targeted mutations were made in the two mammalian orthologs, Pygo1 and Pygo2.
T983 240-242 TO denotes To
T984 250-260 VB denotes understand
T985 243-249 RBR denotes better
T986 366-370 VBN denotes made
T987 261-264 DT denotes the
T988 265-274 NNS denotes functions
T989 275-277 IN denotes of
T990 278-285 NN denotes Pygopus
T991 286-294 VBN denotes mediated
T992 285-286 HYPH denotes -
T993 309-318 NN denotes signaling
T994 295-304 JJ denotes canonical
T995 305-308 NN denotes Wnt
T996 319-321 IN denotes in
T997 322-328 NN denotes kidney
T998 329-340 NN denotes development
T999 340-342 , denotes ,
T1000 342-350 VBN denotes targeted
T1001 351-360 NNS denotes mutations
T1002 361-365 VBD denotes were
T1003 371-373 IN denotes in
T1004 374-377 DT denotes the
T1005 392-401 NNS denotes orthologs
T1006 378-381 CD denotes two
T1007 382-391 JJ denotes mammalian
T1008 401-403 , denotes ,
T1009 403-408 NN denotes Pygo1
T1010 409-412 CC denotes and
T1011 413-418 NN denotes Pygo2
T1012 418-419 . denotes .
T1013 419-428 sentence denotes Results
T1014 421-428 NNS denotes Results
T1015 428-562 sentence denotes Each mutation deleted >80% of the coding sequence, including the critical PHD domain, and almost certainly resulted in null function.
T1016 429-433 DT denotes Each
T1017 434-442 NN denotes mutation
T1018 536-544 VBD denotes resulted
T1019 443-450 VBD denotes deleted
T1020 451-452 SYM denotes >
T1021 452-454 CD denotes 80
T1022 454-455 NN denotes %
T1023 456-458 IN denotes of
T1024 459-462 DT denotes the
T1025 470-478 NN denotes sequence
T1026 463-469 NN denotes coding
T1027 478-480 , denotes ,
T1028 480-489 VBG denotes including
T1029 490-493 DT denotes the
T1030 507-513 NN denotes domain
T1031 494-502 JJ denotes critical
T1032 503-506 NN denotes PHD
T1033 513-515 , denotes ,
T1034 515-518 CC denotes and
T1035 519-525 RB denotes almost
T1036 526-535 RB denotes certainly
T1037 545-547 IN denotes in
T1038 548-552 JJ denotes null
T1039 553-561 NN denotes function
T1040 561-562 . denotes .
T1042 563-568 NN denotes Pygo2
T1043 569-579 JJ denotes homozygous
T1044 580-587 NNS denotes mutants
T1045 610-614 VBD denotes died
T1046 587-589 , denotes ,
T1047 589-593 IN denotes with
T1048 594-598 JJ denotes rare
T1049 599-608 NN denotes exception
T1050 608-610 , denotes ,
T1051 615-622 RB denotes shortly
T1052 623-628 IN denotes after
T1053 629-634 NN denotes birth
T1054 634-636 , denotes ,
T1055 636-640 IN denotes with
T1056 641-642 DT denotes a
T1057 643-652 NN denotes phenotype
T1058 653-662 VBG denotes including
T1059 663-667 NN denotes lens
T943 16-21 NNS denotes roles
R7 T946 T943 prep in,roles
R8 T947 T948 compound Wnt,signaling
R9 T948 T946 pobj signaling,in
R10 T949 T943 prep in,roles
R11 T950 T951 amod mammalian,kidney
R12 T951 T952 compound kidney,development
R13 T952 T949 pobj development,in
R14 T957 T958 det The,gene
R15 T958 T960 nsubj gene,encodes
R16 T959 T958 compound pygopus,gene
R17 T961 T958 prep of,gene
R18 T962 T961 pobj Drosophila,of
R19 T963 T964 det an,component
R20 T964 T960 dobj component,encodes
R21 T965 T964 amod essential,component
R22 T966 T964 prep of,component
R23 T967 T968 det the,complex
R24 T968 T966 pobj complex,of
R25 T969 T970 nmod Armadillo,factor
R26 T970 T968 compound factor,complex
R27 T971 T972 punct (,catenin
R28 T972 T969 parataxis catenin,Armadillo
R29 T973 T972 compound β,catenin
R30 T974 T972 punct -,catenin
R31 T975 T972 punct ),catenin
R32 T976 T970 compound transcription,factor
R33 T977 T968 prep of,complex
R34 T978 T979 amod canonical,signaling
R35 T979 T977 pobj signaling,of
R36 T980 T979 compound Wnt,signaling
R37 T981 T960 punct .,encodes
R38 T983 T984 aux To,understand
R39 T984 T986 advcl understand,made
R40 T985 T984 advmod better,understand
R41 T987 T988 det the,functions
R42 T988 T984 dobj functions,understand
R43 T989 T988 prep of,functions
R44 T990 T991 npadvmod Pygopus,mediated
R45 T991 T993 amod mediated,signaling
R46 T992 T991 punct -,mediated
R47 T993 T989 pobj signaling,of
R48 T994 T993 amod canonical,signaling
R49 T995 T993 compound Wnt,signaling
R50 T996 T988 prep in,functions
R51 T997 T998 compound kidney,development
R52 T998 T996 pobj development,in
R53 T999 T986 punct ", ",made
R54 T1000 T1001 amod targeted,mutations
R55 T1001 T986 nsubjpass mutations,made
R56 T1002 T986 auxpass were,made
R57 T1003 T986 prep in,made
R58 T1004 T1005 det the,orthologs
R59 T1005 T1003 pobj orthologs,in
R60 T1006 T1005 nummod two,orthologs
R61 T1007 T1005 amod mammalian,orthologs
R62 T1008 T1005 punct ", ",orthologs
R63 T1009 T1005 appos Pygo1,orthologs
R64 T1010 T1009 cc and,Pygo1
R65 T1011 T1009 conj Pygo2,Pygo1
R66 T1012 T986 punct .,made
R67 T1016 T1017 det Each,mutation
R68 T1017 T1018 nsubj mutation,resulted
R69 T1019 T1018 aux deleted,resulted
R70 T1020 T1021 punct >,80
R71 T1021 T1022 nummod 80,%
R72 T1022 T1018 dobj %,resulted
R73 T1023 T1022 prep of,%
R74 T1024 T1025 det the,sequence
R75 T1025 T1023 pobj sequence,of
R76 T1026 T1025 compound coding,sequence
R77 T1027 T1022 punct ", ",%
R78 T1028 T1022 prep including,%
R79 T1029 T1030 det the,domain
R80 T1030 T1028 pobj domain,including
R81 T1031 T1030 amod critical,domain
R82 T1032 T1030 compound PHD,domain
R83 T1033 T1018 punct ", ",resulted
R84 T1034 T1018 cc and,resulted
R85 T1035 T1036 advmod almost,certainly
R86 T1036 T1018 advmod certainly,resulted
R87 T1037 T1018 prep in,resulted
R88 T1038 T1039 amod null,function
R89 T1039 T1037 pobj function,in
R90 T1040 T1018 punct .,resulted
R91 T1042 T1043 npadvmod Pygo2,homozygous
R92 T1043 T1044 amod homozygous,mutants
R93 T1044 T1045 nsubj mutants,died
R94 T1046 T1045 punct ", ",died
R95 T1047 T1045 prep with,died
R96 T1048 T1049 amod rare,exception
R97 T1049 T1047 pobj exception,with
R98 T1050 T1045 punct ", ",died
R99 T1051 T1052 advmod shortly,after
R100 T1052 T1045 prep after,died
R101 T1053 T1052 pobj birth,after
R102 T1054 T1045 punct ", ",died
R103 T1055 T1045 prep with,died
R104 T1056 T1057 det a,phenotype
R105 T1057 T1055 pobj phenotype,with
R106 T1058 T1057 prep including,phenotype

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T837 25-38 GO:0016055 denotes Wnt signaling
T838 42-51 NCBITaxon:40674 denotes mammalian
T839 52-58 UBERON:0002113 denotes kidney
T840 52-70 GO:0001822 denotes kidney development
T841 96-103 PR_EXT:Q9V9W8 denotes pygopus
T842 104-108 SO_EXT:0000704 denotes gene
T843 112-122 NCBITaxon:7215 denotes Drosophila
T844 123-130 SO_EXT:sequence_coding_function denotes encodes
T845 161-170 PR_EXT:P18824 denotes Armadillo
T846 172-181 PR_EXT:000002198 denotes β-catenin
T847 183-196 GO_EXT:transcription denotes transcription
T848 183-203 GO_EXT:transcription_factor denotes transcription factor
T849 183-211 GO:0005667 denotes transcription factor complex
T850 215-238 GO:0060070 denotes canonical Wnt signaling
T851 278-285 PR_EXT:Q9V9W8 denotes Pygopus
T852 295-318 GO:0060070 denotes canonical Wnt signaling
T853 322-328 UBERON:0002113 denotes kidney
T854 322-340 GO:0001822 denotes kidney development
T855 351-360 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T856 382-391 NCBITaxon:40674 denotes mammalian
T857 392-401 SO_EXT:0000855 denotes orthologs
T858 403-408 PR_EXT:000013523 denotes Pygo1
T859 413-418 PR_EXT:000013524 denotes Pygo2
T860 434-442 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T861 443-450 SO_EXT:sequence_deletion_process denotes deleted
T862 463-478 SO_EXT:coding_sequence denotes coding sequence
T863 507-513 SO_EXT:0000417 denotes domain
T864 548-552 SO_EXT:sequence_nullness denotes null
T865 563-568 PR_EXT:000013524 denotes Pygo2
T866 580-587 SO_EXT:sequence_altered_entity denotes mutants
T868 629-634 GO:0007567 denotes birth
T869 663-667 UBERON_EXT:lens denotes lens
T836 10-15 PR_EXT:000013524 denotes Pygo2
T867 610-614 GO:0016265 denotes died

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T757 42-51 NCBITaxon:40674 denotes mammalian
T758 52-58 UBERON:0002113 denotes kidney
T759 52-70 GO:0001822 denotes kidney development
T760 96-103 PR:Q9V9W8 denotes pygopus
T761 104-108 SO:0000704 denotes gene
T762 112-122 NCBITaxon:7215 denotes Drosophila
T763 161-170 PR:P18824 denotes Armadillo
T764 172-181 PR:000002198 denotes β-catenin
T765 183-211 GO:0005667 denotes transcription factor complex
T766 215-238 GO:0060070 denotes canonical Wnt signaling
T767 278-285 PR:Q9V9W8 denotes Pygopus
T768 295-318 GO:0060070 denotes canonical Wnt signaling
T769 322-328 UBERON:0002113 denotes kidney
T770 322-340 GO:0001822 denotes kidney development
T771 382-391 NCBITaxon:40674 denotes mammalian
T772 392-401 SO:0000855 denotes orthologs
T773 403-408 PR:000013523 denotes Pygo1
T774 413-418 PR:000013524 denotes Pygo2
T775 507-513 SO:0000417 denotes domain
T776 563-568 PR:000013524 denotes Pygo2
T777 610-614 GO:0016265 denotes died
T778 629-634 GO:0007567 denotes birth
T755 10-15 PR:000013524 denotes Pygo2
T756 25-38 GO:0016055 denotes Wnt signaling