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PMC:1853120 / 8659-9520 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T5050 0-4 RB denotes Here
T5051 14-26 VBN denotes investigated
T5052 4-6 , denotes ,
T5053 6-8 PRP denotes we
T5054 9-13 VBP denotes have
T5055 27-30 DT denotes the
T5056 31-41 NN denotes expression
T5057 42-45 CC denotes and
T5058 46-54 NN denotes function
T5059 55-57 IN denotes of
T5060 58-61 DT denotes the
T5061 68-72 NN denotes gene
T5062 62-67 NN denotes Dmrt7
T5063 73-75 IN denotes in
T5064 76-79 DT denotes the
T5065 80-85 NN denotes mouse
T5066 85-86 . denotes .
T5067 86-248 sentence denotes Dmrt7 is expressed only in the gonad, and, unlike the other Dmrt genes, appears to be present exclusively in mammals and not in nonmammalian vertebrates [23,36].
T5068 87-92 NN denotes Dmrt7
T5069 96-105 VBN denotes expressed
T5070 93-95 VBZ denotes is
T5071 106-110 RB denotes only
T5072 111-113 IN denotes in
T5073 114-117 DT denotes the
T5074 118-123 NN denotes gonad
T5075 123-125 , denotes ,
T5076 125-128 CC denotes and
T5077 128-130 , denotes ,
T5078 130-136 IN denotes unlike
T5079 159-166 VBZ denotes appears
T5080 137-140 DT denotes the
T5081 152-157 NNS denotes genes
T5082 141-146 JJ denotes other
T5083 147-151 NN denotes Dmrt
T5084 157-159 , denotes ,
T5085 167-169 TO denotes to
T5086 170-172 VB denotes be
T5087 173-180 JJ denotes present
T5088 181-192 RB denotes exclusively
T5089 193-195 IN denotes in
T5090 196-203 NNS denotes mammals
T5091 204-207 CC denotes and
T5092 208-211 RB denotes not
T5093 212-214 IN denotes in
T5094 215-227 JJ denotes nonmammalian
T5095 228-239 NNS denotes vertebrates
T5096 240-241 -LRB- denotes [
T5097 244-246 CD denotes 36
T5098 241-243 CD denotes 23
T5099 243-244 , denotes ,
T5100 246-247 -RRB- denotes ]
T5101 247-248 . denotes .
T5102 248-381 sentence denotes We find that DMRT7 protein is expressed only in germ cells and is selectively localized to the XY body of male pachytene germ cells.
T5103 249-251 PRP denotes We
T5104 252-256 VBP denotes find
T5105 257-261 IN denotes that
T5106 279-288 VBN denotes expressed
T5107 262-267 NN denotes DMRT7
T5108 268-275 NN denotes protein
T5109 276-278 VBZ denotes is
T5110 289-293 RB denotes only
T5111 294-296 IN denotes in
T5112 297-301 NN denotes germ
T5113 302-307 NNS denotes cells
T5114 308-311 CC denotes and
T5115 312-314 VBZ denotes is
T5116 327-336 VBN denotes localized
T5117 315-326 RB denotes selectively
T5118 337-339 IN denotes to
T5119 340-343 DT denotes the
T5120 347-351 NN denotes body
T5121 344-346 NN denotes XY
T5122 352-354 IN denotes of
T5123 355-359 JJ denotes male
T5124 375-380 NNS denotes cells
T5125 360-369 NN denotes pachytene
T5126 370-374 NN denotes germ
T5127 380-381 . denotes .
T5128 381-467 sentence denotes To test its function, we generated a conditional null mutation of Dmrt7 in the mouse.
T5129 382-384 TO denotes To
T5130 385-389 VB denotes test
T5131 407-416 VBD denotes generated
T5132 390-393 PRP$ denotes its
T5133 394-402 NN denotes function
T5134 402-404 , denotes ,
T5135 404-406 PRP denotes we
T5136 417-418 DT denotes a
T5137 436-444 NN denotes mutation
T5138 419-430 JJ denotes conditional
T5139 431-435 JJ denotes null
T5140 445-447 IN denotes of
T5141 448-453 NN denotes Dmrt7
T5142 454-456 IN denotes in
T5143 457-460 DT denotes the
T5144 461-466 NN denotes mouse
T5145 466-467 . denotes .
T5146 467-602 sentence denotes We find that Dmrt7 is required in males for progression beyond the pachytene stage of meiotic prophase but is not required in females.
T5147 468-470 PRP denotes We
T5148 471-475 VBP denotes find
T5149 476-480 IN denotes that
T5150 490-498 VBN denotes required
T5151 481-486 NN denotes Dmrt7
T5152 487-489 VBZ denotes is
T5153 499-501 IN denotes in
T5154 502-507 NNS denotes males
T5155 508-511 IN denotes for
T5156 512-523 NN denotes progression
T5157 524-530 IN denotes beyond
T5158 531-534 DT denotes the
T5159 545-550 NN denotes stage
T5160 535-544 NN denotes pachytene
T5161 551-553 IN denotes of
T5162 554-561 JJ denotes meiotic
T5163 562-570 NN denotes prophase
T5164 571-574 CC denotes but
T5165 575-577 VBZ denotes is
T5166 582-590 VBN denotes required
T5167 578-581 RB denotes not
T5168 591-593 IN denotes in
T5169 594-601 NNS denotes females
T5170 601-602 . denotes .
T5171 602-691 sentence denotes In rare mutant cells that survive to diplonema, we observed sex chromatin abnormalities.
T5172 603-605 IN denotes In
T5173 654-662 VBD denotes observed
T5174 606-610 JJ denotes rare
T5175 618-623 NNS denotes cells
T5176 611-617 NN denotes mutant
T5177 624-628 WDT denotes that
T5178 629-636 VBP denotes survive
T5179 637-639 IN denotes to
T5180 640-649 NN denotes diplonema
T5181 649-651 , denotes ,
T5182 651-653 PRP denotes we
T5183 663-666 NN denotes sex
T5184 667-676 NN denotes chromatin
T5185 677-690 NNS denotes abnormalities
T5186 690-691 . denotes .
T5187 691-861 sentence denotes Based on these observations, we suggest that Dmrt7 plays a critical role in a male-specific chromatin transition between pachynema and diplonema during meiotic prophase.
T5188 692-697 VBN denotes Based
T5189 724-731 VBP denotes suggest
T5190 698-700 IN denotes on
T5191 701-706 DT denotes these
T5192 707-719 NNS denotes observations
T5193 719-721 , denotes ,
T5194 721-723 PRP denotes we
T5195 732-736 IN denotes that
T5196 743-748 VBZ denotes plays
T5197 737-742 NN denotes Dmrt7
T5198 749-750 DT denotes a
T5199 760-764 NN denotes role
T5200 751-759 JJ denotes critical
T5201 765-767 IN denotes in
T5202 768-769 DT denotes a
T5203 794-804 NN denotes transition
T5204 770-774 JJ denotes male
T5205 775-783 JJ denotes specific
T5206 774-775 HYPH denotes -
T5207 784-793 NN denotes chromatin
T5208 805-812 IN denotes between
T5209 813-822 NN denotes pachynema
T5210 823-826 CC denotes and
T5211 827-836 NN denotes diplonema
T5212 837-843 IN denotes during
T5213 844-851 JJ denotes meiotic
T5214 852-860 NN denotes prophase
T5215 860-861 . denotes .
R1277 T5050 T5051 advmod Here,investigated
R1279 T5052 T5051 punct ", ",investigated
R1280 T5053 T5051 nsubj we,investigated
R1282 T5054 T5051 aux have,investigated
R1283 T5055 T5056 det the,expression
R1284 T5056 T5051 dobj expression,investigated
R1286 T5057 T5056 cc and,expression
R1287 T5058 T5056 conj function,expression
R1289 T5059 T5056 prep of,expression
R1290 T5060 T5061 det the,gene
R1291 T5061 T5059 pobj gene,of
R1293 T5062 T5061 compound Dmrt7,gene
R1294 T5063 T5056 prep in,expression
R1296 T5064 T5065 det the,mouse
R1297 T5065 T5063 pobj mouse,in
R1298 T5066 T5051 punct .,investigated
R1300 T5068 T5069 nsubjpass Dmrt7,expressed
R1302 T5070 T5069 auxpass is,expressed
R1303 T5071 T5069 advmod only,expressed
R1304 T5072 T5069 prep in,expressed
R1306 T5073 T5074 det the,gonad
R1307 T5074 T5072 pobj gonad,in
R1309 T5075 T5069 punct ", ",expressed
R1310 T5076 T5069 cc and,expressed
R1311 T5077 T5069 punct ", ",expressed
R1312 T5078 T5079 prep unlike,appears
R1314 T5079 T5069 conj appears,expressed
R1315 T5080 T5081 det the,genes
R1316 T5081 T5078 pobj genes,unlike
R1317 T5082 T5081 amod other,genes
R1318 T5083 T5081 compound Dmrt,genes
R1320 T5084 T5079 punct ", ",appears
R1321 T5085 T5086 aux to,be
R1322 T5086 T5079 xcomp be,appears
R1324 T5087 T5086 acomp present,be
R1325 T5088 T5089 advmod exclusively,in
R1327 T5089 T5086 prep in,be
R1328 T5090 T5089 pobj mammals,in
R1329 T5091 T5089 cc and,in
R1331 T5092 T5091 neg not,and
R1332 T5093 T5089 conj in,in
R1334 T5094 T5095 amod nonmammalian,vertebrates
R1337 T5095 T5093 pobj vertebrates,in
R1338 T5096 T5097 punct [,36
R1340 T5097 T5079 parataxis 36,appears
R1341 T5098 T5097 nummod 23,36
R1342 T5099 T5097 punct ",",36
R1344 T5100 T5097 punct ],36
R1345 T5101 T5069 punct .,expressed
R1347 T5103 T5104 nsubj We,find
R1349 T5105 T5106 mark that,expressed
R1350 T5106 T5104 ccomp expressed,find
R1352 T5107 T5108 compound DMRT7,protein
R1353 T5108 T5106 nsubjpass protein,expressed
R1354 T5109 T5106 auxpass is,expressed
R1356 T5110 T5106 advmod only,expressed
R1357 T5111 T5106 prep in,expressed
R1358 T5112 T5113 compound germ,cells
R1360 T5113 T5111 pobj cells,in
R1361 T5114 T5106 cc and,expressed
R1362 T5115 T5116 auxpass is,localized
R1364 T5116 T5106 conj localized,expressed
R1365 T5117 T5116 advmod selectively,localized
R1366 T5118 T5116 prep to,localized
R1367 T5119 T5120 det the,body
R1368 T5120 T5118 pobj body,to
R1369 T5121 T5120 compound XY,body
R1371 T5122 T5120 prep of,body
R1372 T5123 T5124 amod male,cells
R1373 T5124 T5122 pobj cells,of
R1375 T5125 T5124 compound pachytene,cells
R1376 T5126 T5124 compound germ,cells
R1378 T5127 T5104 punct .,find
R1379 T5129 T5130 aux To,test
R1380 T5201 T5196 prep in,plays
R1381 T5130 T5131 advcl test,generated
R1382 T5132 T5133 poss its,function
R1383 T5133 T5130 dobj function,test
R1384 T5202 T5203 det a,transition
R1385 T5203 T5201 pobj transition,in
R1386 T5134 T5131 punct ", ",generated
R1387 T5135 T5131 nsubj we,generated
R1388 T5204 T5205 amod male,specific
R1389 T5136 T5137 det a,mutation
R1390 T5137 T5131 dobj mutation,generated
R1391 T5205 T5203 amod specific,transition
R1392 T5206 T5205 punct -,specific
R1393 T5138 T5137 amod conditional,mutation
R1394 T5139 T5137 amod null,mutation
R1395 T5207 T5203 compound chromatin,transition
R1396 T5140 T5137 prep of,mutation
R1397 T5141 T5140 pobj Dmrt7,of
R1398 T5208 T5203 prep between,transition
R1399 T5142 T5131 prep in,generated
R1400 T5143 T5144 det the,mouse
R1401 T5144 T5142 pobj mouse,in
R1402 T5209 T5208 pobj pachynema,between
R1403 T5145 T5131 punct .,generated
R1404 T5210 T5209 cc and,pachynema
R1405 T5147 T5148 nsubj We,find
R1406 T5211 T5209 conj diplonema,pachynema
R1407 T5149 T5150 mark that,required
R1408 T5150 T5148 ccomp required,find
R1409 T5151 T5150 nsubjpass Dmrt7,required
R1410 T5212 T5196 prep during,plays
R1411 T5152 T5150 auxpass is,required
R1412 T5153 T5150 prep in,required
R1413 T5154 T5153 pobj males,in
R1414 T5213 T5214 amod meiotic,prophase
R1415 T5155 T5150 prep for,required
R1416 T5156 T5155 pobj progression,for
R1417 T5157 T5156 prep beyond,progression
R1418 T5214 T5212 pobj prophase,during
R1419 T5158 T5159 det the,stage
R1420 T5159 T5157 pobj stage,beyond
R1421 T5160 T5159 compound pachytene,stage
R1422 T5161 T5159 prep of,stage
R1423 T5162 T5163 amod meiotic,prophase
R1424 T5163 T5161 pobj prophase,of
R1425 T5215 T5189 punct .,suggest
R1426 T5164 T5150 cc but,required
R1427 T5165 T5166 auxpass is,required
R1428 T5166 T5150 conj required,required
R1429 T5167 T5166 neg not,required
R1430 T5168 T5166 prep in,required
R1431 T5169 T5168 pobj females,in
R1432 T5170 T5148 punct .,find
R1433 T5172 T5173 prep In,observed
R1434 T5174 T5175 amod rare,cells
R1435 T5175 T5172 pobj cells,In
R1436 T5176 T5175 compound mutant,cells
R1437 T5177 T5178 dep that,survive
R1438 T5178 T5175 relcl survive,cells
R1439 T5179 T5178 prep to,survive
R1440 T5180 T5179 pobj diplonema,to
R1441 T5181 T5173 punct ", ",observed
R1442 T5182 T5173 nsubj we,observed
R1443 T5183 T5184 compound sex,chromatin
R1444 T5184 T5185 compound chromatin,abnormalities
R1445 T5185 T5173 dobj abnormalities,observed
R1446 T5186 T5173 punct .,observed
R1447 T5188 T5189 prep Based,suggest
R1448 T5190 T5188 prep on,Based
R1449 T5191 T5192 det these,observations
R1450 T5192 T5190 pobj observations,on
R1451 T5193 T5189 punct ", ",suggest
R1452 T5194 T5189 nsubj we,suggest
R1453 T5195 T5196 mark that,plays
R1454 T5196 T5189 ccomp plays,suggest
R1455 T5197 T5196 nsubj Dmrt7,plays
R1456 T5198 T5199 det a,role
R1457 T5199 T5196 dobj role,plays
R1458 T5200 T5199 amod critical,role

2_test

Id Subject Object Predicate Lexical cue
17447844-12609607-85805820 241-243 12609607 denotes 23
17447844-16488114-85805821 244-246 16488114 denotes 36
T7909 241-243 12609607 denotes 23
T28012 244-246 16488114 denotes 36

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3665 31-41 GO:0010467 denotes expression
T3666 62-67 PR:000006549 denotes Dmrt7
T3667 68-72 SO:0000704 denotes gene
T3668 80-85 NCBITaxon:10088 denotes mouse
T3669 87-92 PR:000006549 denotes Dmrt7
T3670 96-105 GO:0010467 denotes expressed
T3671 118-123 UBERON:0000991 denotes gonad
T3672 152-157 SO:0000704 denotes genes
T3673 196-203 NCBITaxon:40674 denotes mammals
T3674 218-227 NCBITaxon:40674 denotes mammalian
T3675 228-239 NCBITaxon:7742 denotes vertebrates
T3676 262-267 PR:000006549 denotes DMRT7
T3677 279-288 GO:0010467 denotes expressed
T3678 297-307 CL:0000586 denotes germ cells
T3679 344-351 GO:0001741 denotes XY body
T3680 355-359 _FRAGMENT denotes male
T3681 370-380 CL:0000015 denotes germ cells
T3682 360-369 GO:0000239 denotes pachytene
T3683 448-453 PR:000006549 denotes Dmrt7
T3684 461-466 NCBITaxon:10088 denotes mouse
T3685 481-486 PR:000006549 denotes Dmrt7
T3686 535-544 GO:0000239 denotes pachytene
T3687 554-561 GO:0007126 denotes meiotic
T3688 562-570 GO:0051324 denotes prophase
T3689 640-649 GO:0000240 denotes diplonema
T3690 663-676 GO:0001739 denotes sex chromatin
T3691 737-742 PR:000006549 denotes Dmrt7
T3692 784-793 GO:0000785 denotes chromatin
T3693 784-804 GO:0016568 denotes chromatin transition
T3694 813-822 GO:0000239 denotes pachynema
T3695 827-836 GO:0000240 denotes diplonema
T3696 844-851 GO:0007126 denotes meiotic
T3697 852-860 GO:0051324 denotes prophase
R308 T3681 T3680 _lexicallyChainedTo germ cells,male

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3942 31-41 GO:0010467 denotes expression
T3943 62-67 PR_EXT:000006549 denotes Dmrt7
T3944 68-72 SO_EXT:0000704 denotes gene
T3945 80-85 NCBITaxon:10088 denotes mouse
T3946 87-92 PR_EXT:000006549 denotes Dmrt7
T3947 96-105 GO:0010467 denotes expressed
T3948 118-123 UBERON:0000991 denotes gonad
T3949 152-157 SO_EXT:0000704 denotes genes
T3950 196-203 NCBITaxon:40674 denotes mammals
T3951 218-227 NCBITaxon:40674 denotes mammalian
T3952 228-239 NCBITaxon:7742 denotes vertebrates
T3953 262-267 PR_EXT:000006549 denotes DMRT7
T3954 268-275 CHEBI_PR_EXT:protein denotes protein
T3955 279-288 GO:0010467 denotes expressed
T3956 297-307 CL:0000586 denotes germ cells
T3957 302-307 CL_GO_EXT:cell denotes cells
T3958 327-336 GO_PATO_EXT:biological_localization_process_or_quality denotes localized
T3959 344-351 GO:0001741 denotes XY body
T3960 355-359 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes male
T3961 355-359 _FRAGMENT denotes male
T3962 370-380 CL:0000015 denotes germ cells
T3963 360-369 GO:0000239 denotes pachytene
T3964 375-380 CL_GO_EXT:cell denotes cells
T3965 431-435 SO_EXT:sequence_nullness denotes null
T3966 436-444 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T3967 448-453 PR_EXT:000006549 denotes Dmrt7
T3968 461-466 NCBITaxon:10088 denotes mouse
T3969 481-486 PR_EXT:000006549 denotes Dmrt7
T3970 502-507 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3971 535-544 GO:0000239 denotes pachytene
T3972 554-561 GO:0007126 denotes meiotic
T3973 562-570 GO:0051324 denotes prophase
T3974 594-601 PATO_UBERON_EXT:female_or_bearer_of_femaleness denotes females
T3975 611-617 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T3976 618-623 CL_GO_EXT:cell denotes cells
T3977 640-649 GO:0000240 denotes diplonema
T3978 663-676 GO:0001739 denotes sex chromatin
T3979 737-742 PR_EXT:000006549 denotes Dmrt7
T3980 770-774 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes male
T3981 784-793 GO:0000785 denotes chromatin
T3982 784-804 GO:0016568 denotes chromatin transition
T3983 813-822 GO:0000239 denotes pachynema
T3984 827-836 GO:0000240 denotes diplonema
T3985 844-851 GO:0007126 denotes meiotic
T3986 852-860 GO:0051324 denotes prophase
R312 T3962 T3961 _lexicallyChainedTo germ cells,male