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{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T3714","span":{"begin":0,"end":9},"obj":"NCBITaxon:40674"},{"id":"T3715","span":{"begin":10,"end":17},"obj":"GO:0007126"},{"id":"T3716","span":{"begin":21,"end":30},"obj":"GO:0065007"},{"id":"T3717","span":{"begin":60,"end":73},"obj":"GO:0009790"},{"id":"T3718","span":{"begin":105,"end":115},"obj":"UBERON:0000113"},{"id":"T3719","span":{"begin":176,"end":183},"obj":"GO:0007126"},{"id":"T3720","span":{"begin":224,"end":231},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T3721","span":{"begin":233,"end":243},"obj":"CL:0000586"},{"id":"T3722","span":{"begin":238,"end":243},"obj":"CL_GO_EXT:cell"},{"id":"T3723","span":{"begin":267,"end":274},"obj":"GO:0007126"},{"id":"T3724","span":{"begin":282,"end":288},"obj":"UBERON:0000922"},{"id":"T3725","span":{"begin":307,"end":325},"obj":"GO:0007128"},{"id":"T3726","span":{"begin":342,"end":349},"obj":"CL:0000023"},{"id":"T3727","span":{"begin":366,"end":375},"obj":"GO_EXT:biological_recruitment"},{"id":"T3728","span":{"begin":380,"end":389},"obj":"GO:0030728"},{"id":"T3729","span":{"begin":412,"end":424},"obj":"GO:0007137"},{"id":"T3730","span":{"begin":443,"end":450},"obj":"GO:0007126"},{"id":"T3731","span":{"begin":457,"end":470},"obj":"GO:0009566"},{"id":"T3732","span":{"begin":496,"end":500},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T3733","span":{"begin":496,"end":508},"obj":"GO:0007140"},{"id":"T3734","span":{"begin":529,"end":536},"obj":"GO:0007567"},{"id":"T3735","span":{"begin":574,"end":581},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T3736","span":{"begin":586,"end":593},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T3737","span":{"begin":600,"end":607},"obj":"GO:0007126"},{"id":"T3738","span":{"begin":637,"end":643},"obj":"CL:0000023"},{"id":"T3739","span":{"begin":690,"end":694},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T3740","span":{"begin":690,"end":702},"obj":"GO:0007140"},{"id":"T3741","span":{"begin":728,"end":741},"obj":"CL:0000017"}],"text":"Mammalian meiosis is regulated sex-specifically starting in embryogenesis and continuing through much of adult life (reviewed in [1]). For example, the timing and synchrony of meiosis are very different in the two sexes. In females, germ cells synchronously initiate meiosis in the embryo and arrest during meiotic prophase I. After puberty, oocytes are selectively recruited for ovulation, when they proceed to metaphase II and then complete meiosis after fertilization occurs [2]. In contrast, male meiosis occurs entirely postnatally, without the arrest periods found in females. In females, each meiosis can produce a single haploid oocyte (and two extruded polar bodies), whereas each male meiosis can produce four haploid spermatocytes."}