PMC:1852721 / 66735-67013 JSONTXT

{"project":"2_test","denotations":[{"id":"17357067-6185846-2054089","span":{"begin":276,"end":278},"obj":"6185846"}],"text":"The converse situation, activation of oncogenes through hypomethylation, also leads to the development of cancers. Indeed, hypomethylation was the first indication of the role of anomalous promoter methylation in carcinogenesis, as reported by Feinberg and Vogelstein in 1983.73"}