PMC:1794230 / 42105-42679 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1794230","sourcedb":"PMC","sourceid":"1794230","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1794230","text":"Like the MONKEY method [12], PhyloScan uses the phylogenetic model of Neyman [38] and the efficient algorithm of Felsenstein [39] to evaluate the probability that a site in observed multiply-aligned sequence data is consistent with a transcription factor's motif model. With either MONKEY or PhyloScan, each position of the motif is evaluated, and the computed probabilities for the motif positions are then multiplied together to give the strength of the site. Via the approach of Staden [10], the probability that such strength would arise by chance is precisely computed.","tracks":[{"project":"2_test","denotations":[{"id":"17244358-15575972-1689322","span":{"begin":24,"end":26},"obj":"15575972"},{"id":"17244358-7288891-1689323","span":{"begin":126,"end":128},"obj":"7288891"},{"id":"17244358-2720468-1689324","span":{"begin":490,"end":492},"obj":"2720468"}],"attributes":[{"subj":"17244358-15575972-1689322","pred":"source","obj":"2_test"},{"subj":"17244358-7288891-1689323","pred":"source","obj":"2_test"},{"subj":"17244358-2720468-1689324","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ecd193","default":true}]}]}}