PMC:1794230 / 24011-24856 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1794230","sourcedb":"PMC","sourceid":"1794230","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1794230","text":"Furthermore, in each of the tests described above (using the baseline, the reduced-database, or the aligned sequence data) we can incorporate non-alignable orthologous sequence data to measure the impact of these additional data on sensitivity. Thus, to determine the extent to which additional, more distantly related, species could provide evidence to support a particular candidate transcription factor binding site upstream of a particular gene in the target species, we used PhyloScan to scan the orthologous intergenic regions for that candidate gene from the additional species (clades), assuming phylogenetic independence between clades. The p-value representing the combined evidence supporting a transcription factor binding site prediction was then calculated using the method of Bailey and Gribskov [32], as described in the Methods.","tracks":[{"project":"2_test","denotations":[{"id":"17244358-9672829-1689314","span":{"begin":812,"end":814},"obj":"9672829"}],"attributes":[{"subj":"17244358-9672829-1689314","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93eca8","default":true}]}]}}