PMC:1764415 / 10717-11377 JSONTXT

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where c > 0 is the shape parameter, b > 0 is the scale parameter, x ≥ 0 is the independent variable, usually time. The Erlang distribution has several characteristics, which are appropriate for describing the protein-protein interaction network, including its positive range and its important reproductive property [18]. The Erlang distribution with x/b = 1 is used and the value of c is set to the number of edges between source protein node and the target protein node. Setting the value of x/b to unity assesses the perturbation at the target protein when the perturbation reaches 1/e of its initial value at the nearest neighbor of the source protein node.